BMI-1
January 24, 2020KETONE BODIES
January 24, 2020
- … -activated protein kinase kinase kinase 3 (MEKK3) is required for lysophosphatidic acid (LPA)-mediated optimal i [kappa] B kinase [beta](IKK [beta])/nuclear factor …
- … -induced expression of iNOS and COX-2 in BV2 murine microglial cells: possible involvement of reactive oxygen species, p38 MAPK, and IKK/NF-κB signaling …
- … -insufficiency improves cardiac function in early-stages of myocardial infarction by protecting myocardium and increasing angiogenesis by promoting IKK …
- … ) stimulates matrix mentalloproteinase-9 (MMP-9) production in cultured human chorion trophoblast cells through TNF alpha receptor 1 signalling to IKK beta, ERK1/2 …
- … 8 acute infection of endothelial cells induces monocyte chemoattractant protein 1–dependent capillary-like structure formation: role of the IKK/NF-κB pathway
- … acid-induced iNOS gene expression in macrophages possibly through downregulation of toll-like receptor 2-mediated activation of Raf-MEK1/2-ERK1/2-IKK-NFκB
- … and chemosensitizes leukemic cells through inhibition of gene expression regulated by TNF-TNFR1-TRADD-TRAF2-NIK-TAK1-IKK pathway”[Biochem. Pharmacol …
- … and the beautiful: A small dibromotyrosine derivative from Pseudoceratina sp. sponge exhibits potent apoptotic effect through targeting IKK/NFκB signaling pathway
- … antagonist blocks histamine-induced proinflammatory cytokine production through inhibition of Ca2+-dependent protein kinase C, Raf/MEK/ERK and IKK/IκB/NF-κB …
- … as a target to increase apoptosis in primary mediastinal B-cell lymphoma (PMBL): Results of studies with rituximab (RTX), bortezomib (BTZ) and small molecule IKK …
- … attenuates TNF-α-induced iNOS expression in human endothelial cells: Involvement of Syk-mediated activation of PI3K-IKK-IκB signaling pathways
- … between apoptosis in primary mediastinal B-cell lymphoma (PMBL) and NF-\# 954; B Pathway Blockade: Bortezomib (BTZ), small molecule IKK inhibitor ML120B and …
- … cascade leading to apoptosis.) The anti-inflammatory phenolic curcumin from Curcuma species (turmeric)(Zingiberaceae) inhibits the IB kinase (IKK) and thus inhibits …
- … Conditioning and Ventilation held in Hanover for the first time: Air conditioning systems made in the Far East challenge traditional systems; IKK 2001-22. Internationale …
- … deacetylase inhibitors SAHA and NVP-LAQ824 is enhanced by interrupting NF-kappaB activation through a mechanism involving inhibition of IKK-mediated RelA/p65 …
- … disrupts tyrosine-phosphorylated phosphatidylinositol 3-kinase and myeloid differentiation factor-88 association, and inhibits MAPK/AP-1 and IKK/NF-κB-induced …
- … from the Chinese medicinal plant Caesalpinia sappan L., protects neurons from microglia-mediated inflammatory injuries via inhibition of IκB kinase (IKK)-NF-κB and …
- … growth factor-2 15-LOX, 15-lipoxygenase receptor tyrosine kinase LPS, lipopolysaccharide iGlu-R, inhibitory glutamate receptor LT, leukotriene IKK, inhibitor B kinase …
- … Impaired migration and proliferation of bone marrow-derived mesenchymal stem cells from patients with systemic lupus erythematosus were mediated by IKK-β
- … in this paper: ApoE, apolipoprotein E; BAE, bovine aortic endothelial; Coll, collagen; FG, fibrinogen; FN, fibronectin; IHC, immunohistochemistry; IKK, IκB kinase; LN …
- … Increases in Apoptosis in Primary Mediastinal B-Cell Lymphoma (PMBL) and NF-κB Pathway Blockade: Bortezomib (BTZ), Small Molecule IKK Inhibitor ML120B and …
- … inhibitor, suppresses growth and chemosensitizes leukemic cells through inhibition of gene expression regulated by TNF-TNFR1-TRADD-TRAF2-NIK-TAK1-IKK …
- … low-density lipoprotein-induced inflammation in human mesangial cells through upregulation of XBP1 and suppression of the IRE1α/IKK/NF‑κB pathway
- … mortality and district characteristics (IKK) of the TUeV Rheinland; Das Informationssystem ueber Krebsmortalitaet und Kreischarakteristika (IKK) des TUeV Rheinland
- … of Ethanolic Extract of Pericarps of Mangosteen (Garcinia mangostana Linn.) on WiDr Cells and Interaction Study of Alpha-mangosteen to IKK and VEGF Based on …
- … of LPS-induced NO and PGE2 production by asiatic acid via NF-κB inactivation in RAW 264.7 macrophages: possible involvement of the IKK and MAPK pathways
- … of the NF-κ B pathway by the leukemogenic TEL-Jak2 and TEL-Abl fusion proteins leads to the accumulation of antiapoptotic IAP proteins and involves IKK α
- … oxide level in tomato regulated by a mammalian IKK/NF-κB like signaling pathway? Is nitric oxide level in tomato regulated by a mammalian IKK/NFκB-like signaling …
- … Pathways Regulating Hepatic Apolipoprotein B100 Production: Roles of Mitogen-activated Protein Kinases (MAPKs) and Inhibitor of NFkappaB Kinase (IKK) …
- … pylori Induction in Gastric Mucosal Prostaglandin and Nitric Oxide Generation Is Dependent on MAPK/ERK-Mediated Activation of IKK-β and cPLA2 …
- … the DKV planner’s forum at the IKK 2000; Integration lufttechnischer Systemloesungen in die Gebaeudeautomation. Beitrag vom DKV-Planerforum waehrend der IKK …
- … the solution structure of IκB kinase (IKK) subunit γ and its interaction with kaposi sarcoma-associated herpes virus flice-interacting protein and IKK subunit β by EPR …
- 129. OVARIAN PHENOTYPE OF THE IKK CONDITIONAL KNOCKOUT MOUSE
- 147: Inhibitory kappa B kinase (IKK) inhibition attenuates infarct size in a murine model of myocardial ischemia-reperfusion
- 15‐Deoxy‐Δ12,14‐prostaglandin J2 inhibits IL‐1β‐induced IKK enzymatic activity and IκBα degradation in rat chondrocytes through a PPARγ‐independent pathway
- 20-HETE Activates Endothelial ACE via an IKK/NF-kB Dependent Pathway
- 20-SOLA, a Novel Water Soluble 20-HETE Antagonist, Reduces Blood Pressure Through Regulation of Vascular ACE Expression via an IKK Dependent Pathway
- 241 Tnf-α Induction of Infant Murine Brain Inflammation Via IKK/Nf Kappa B Signalling: A Potential Model for Paediatric Neuroinflammation
- 3, 5-Disubstituted-indole-7-carboxamides: The discovery of a novel series of potent, selective inhibitors of IKK-β
- 3D‐QSAR Studies on a Class of IKK‐2 Inhibitors with GALAHAD Used to Develop Molecular Alignment Models
- 3D‐QSAR Study of Pyridine Derivates as IKK‐2 Inhibitors
- 4-Hydroxyestradiol induces neoplastic transformation of human breast epithelial cells by activating IKK-NF-κB signaling: possible involvement of reactive oxygen …
- 5-(1H-Benzimidazol-1-yl)-3-alkoxy-2-thiophenecarbonitriles as potent, selective, inhibitors of IKK-ε kinase
- 57: Pivotal role of the IKK-related kinase IKK epsilon to modulate IL29 or type I IFN induction during hepatitis C virus infection
- A dominant function of IKK/NF-κB signaling in global lipopolysaccharide-induced gene expression
- A feedforward loop of NLRC5 (de) ubiquitination keeps IKK–NF-κB in check
- A key mediator, PTX3, of IKK/IκB/NF-κB exacerbates human umbilical vein endothelial cell injury and dysfunction
- A Kinase Upstream of IKK
- A negative feedback loop between miR‐200b and the nuclear factor‐κB pathway via IKBKB/IKK‐β in breast cancer cells
- A new role for IKK-α in hepatitis C virus-induced lipogenesis.
- A Novel IKK Inhibitor IMD-0560: Suppresses Chronic Remodeling after Myocardial Ischemia
- A Novel IKK Inhibitor Prevents Progression of Neointimal Formation After Arterial Injury in Mice
- A novel IKK inhibitor prevents progression of restenosis after arterial injury in mice
- A novel IKK inhibitor suppresses heart failure and chronic remodeling after myocardial ischemia via MMP alteration
- A novel role for IκB kinase (IKK) α and IKKβ in ERK-dependent up-regulation of MUC5AC mucin transcription by Streptococcus pneumoniae
- A novel X-linked disorder of immune deficiency and hypohidrotic ectodermal dysplasia is allelic to incontinentia pigmenti and due to mutations in IKK-gamma …
- A novel, highly selective, tight binding IκB kinase-2 (IKK-2) inhibitor: a tool to correlate IKK-2 activity to the fate and functions of the components of the nuclear factor-κB …
- A positive feedback loop involving EGFR/Akt/mTORC1 and IKK/NF-κB regulates head and neck squamous cell carcinoma proliferation
- A recurrent deletion in the ubiquitously expressed NEMO (IKK-γ) gene accounts for the vast majority of incontinentia pigmenti mutations
- A selective IKK-2 inhibitor blocks NF-κB-dependent gene expression in interleukin-1β-stimulated synovial fibroblasts
- A selective novel low‐molecular‐weight inhibitor of IκB kinase‐β (IKK‐β) prevents pulmonary inflammation and shows broad anti‐inflammatory activity
- A Specific IKK Inhibitor Suppresses Experimental Autoimmune Myocarditis in Rats
- A TNF &alphaA-responsive kinase activity may play a key role in IKK activation.
- A Truncated Form of IKKa Is Responsible for Specific Nuclear IKK Activity in Colorectal Cancer
- A truncated form of IKKα is responsible for specific nuclear IKK activity in colorectal cancer
- A truncated form of IKKα is responsible for specific nuclear IKK activity in colorectal cancer
- A ubiquitin replacement strategy in human cells reveals distinct mechanisms of IKK activation by TNFα and IL-1β
- A20-binding inhibitor of nuclear factor-B (NF-B)-2 (ABIN-2) is an activator of inhibitor of NF-B (IB) kinase (IKK)-mediated NF-B transcriptional activity
- AB0601 Anti-arthritis effects of (E)-2, 4-bis (P-hydroxyphenyl)-2-butenal through inhibition of IKK-beta activity
- Abnormal morphogenesis but intact IKK activation in mice lacking the IKKα subunit of IκB kinase
- Abstract A41: The ASK1/IKK signaling axis mediates crosstalk between inflammation and apoptosis
- Abstract B59: IKK-mediated phosphorylation of the androgen receptor: A mechanism to modulate AR-cofactor interaction
- Abstract B71: Chemosensitization to bleomycin conferred by a constitutive activation of IKK pathway in viral FLIP expressing cells
- Abstract LB-144: I-kappa-B kinase (IKK) ε expression in pancreatic ductal adenocarcinoma
- Abstract LB-206: A novel scaffold that targets the IKK complex
- Abstract P1-01-11: Nuclear immunohistochemical IKK-εexpression in flat epithelial atypia (FEA) of the breast: A predictor of ipsilateral ADH, in-situ or invasive …
- Abstract P5-05-10: EIA-Induced PP2A Expression Prevents β-Trcp Mediated FOXO3a Degradation and Enhances Chemosensitization by Inhibiting TAK1/IKK …
- Abstract# 1196: Pro-inflammatory cytokine RANKL promotes tumor metastasis through the RANK-IKK\# 945; pathway
- Abstract# 1486: E1A-induced PP2A expression prevents\# 946; TrCP-mediated FOXO3a degradation and enhances chemosensitization by inhibiting TAK1/IKK …
- Abstract# 1790: Different roles of IKK alpha and IKK beta on NF-kB pathway in mantle cell lymphoma and diffuse large B-cell ympoma
- Abstract# 441: TRAF2 phosphorylation at Ser-55 inhibits stress-induced cell death by promoting prolonged IKK activation
- Abstract# 4700: p65 activity and ZAP-70 status predict the sensitivity of chronic lymphocytic leukemia cells to the selective IKK inhibitor BMS-345541
- Abstract# 4958: Pro-inflammatory cytokine RANKL promotes tumor metastasis through the RANK-IKK\# 945; pathway
- Abstract# 5050: 4-Hydroxyestradiol induces anchorage-independent growth of human mammary epithelial cells through ROS-mediated activation of IKK
- Abstract# 5269: TRAF2 suppresses IKK activity and inhibits TNFa-induced cell death independent of NF-kB activation
- Abstract# 5271: PKC-iota associates and phosphorylates IKK-\# 945;/\# 946; in breast cancer cell
- Abstract# 5488: IKK inhibitor Bay 11-7082 induces necrotic cell death in pre-B ALL cells
- Abstract# 5672: The role of IKK\# 946;/TSC1 regulation in tumorigenesis and insulin resistance
- Accumulation of phosphorylated IκBα and activated IKK in nodes of Ranvier
- Acetylation of MEK2 and IκB kinase (IKK) activation loop residues by YopJ inhibits signaling
- Activation mechanisms of endothelial NF-κB, IKK, and MAP kinase by tert-butyl hydroperoxide
- Activation of a Subset of Genes by IFN-γ Requires IKKβ but Not Interferon-Dependent Activation of NF-κB
- Activation of G-protein-coupled estrogen receptor inhibits the migration of human nonsmall cell lung cancer cells via IKK-β/NF-κB signals
- Activation of IKK by thymosin α1 requires the TRAF6 signalling pathway
- Activation of IKK by TNFα requires site-specific ubiquitination of RIP1 and polyubiquitin binding by NEMO
- Activation of IKK/NF-κB provokes renal inflammatory responses in guanylyl cyclase/natriuretic peptide receptor-A gene-knockout mice
- Activation of nuclear factor κB through the IKK complex by the topoisomerase poisons SN38 and doxorubicin: a brake to apoptosis in HeLa human carcinoma cells
- Activation of PI3K/Akt/IKK-α/NF-κB signaling pathway is required for the apoptosis-evasion in human salivary adenoid cystic carcinoma: its inhibition by quercetin
- Activation of the canonical IKK complex by K63/M1-linked hybrid ubiquitin chains
- Activation of the IκBα kinase (IKK) complex by double-stranded RNA-binding defective and catalytic inactive mutants of the interferon-inducible protein kinase …
- Activation of the virus-induced IKK/NF-kB signaling axis is critical for the replication of HCMV in quiescent cells
- Activation of the virus‐induced IKK/NF‐κB signalling axis is critical for the replication of human cytomegalovirus in quiescent cells
- Active nuclear IKK correlates with metastatic risk in cutaneous squamous cell carcinoma
- Activity of bortezomib, a proteasome inhibitor, in breast cancer cells: Association with negative estrogen receptor and IKK/NF-κB expression
- Adenovirus mediated gene transfer of mutated IKK and IκBα reveal NF-κB dependent as well as independent pathway of HAS1 activation
- Adenovirus-mediated IKK β KA expression sensitizes prostate carcinoma cells to TRAIL-induced apoptosis
- Adiponectin blocks interleukin-18-mediated endothelial cell death via APPL1-dependent AMP-activated protein kinase (AMPK) activation and IKK/NF-κB/PTEN …
- Advances in targeting IKK and IKK-related kinases for cancer therapy
- Akt-dependent regulation of NF-κB is controlled by mTOR and Raptor in association with IKK
- Akt/IKK [alpha]/Vav1 Signaling in Endothelial Cell Survival and Angiogenesis
- Alpha-lipoic acid inhibits TNF-α induced NF-κB activation through blocking of MEKK1–MKK4–IKK signaling cascades
- Altered TAB1: IKK Interaction Promotes TGF-β-Mediated NF-κB Activation During Breast Cancer Progression
- Amelioration of Arthritis by Intraarticular Dominant Negative IKKβ Gene Therapy Using Adeno-Associated Virus Type 5
- Aminopyridinecarboxamide-based inhaled IKK-2 inhibitors for asthma and COPD: Structure–activity relationship
- An inhibitor of the protein kinases TBK1 and IKK-ɛ improves obesity-related metabolic dysfunctions in mice
- Angiogenin mediates immune modulation and antiinflammatory reaction attenuating protein kinase IKK-ε in human corneal fibroblast cells
- Annexin-1 interacts with NEMO and RIP1 to constitutively activate IKK complex and NF-κB: implication in breast cancer metastasis
- Anthrax lethal toxin enhances I kappa B kinase (IKK) activation and differentially regulates pro-inflammatory genes in human endothelium (135.3)
- Anti-inflammatory effects of IKK inhibitor XII, thymulin, and fat-soluble antioxidants in LPS-treated mice
- Anticancer agent CHS 828 suppresses nuclear factor‐κB activity in cancer cells through downregulation of IKK activity
- Apigenin potentiates the growth inhibitory effects by IKK-β-mediated NF-κB activation in pancreatic cancer cells
- Apigenin suppresses IKK activation and downstream signaling leading to prostate cancer inhibition.
- Apoptotic role of IKK in T-ALL therapeutic response
- Are the IKKs and IKK-related kinases TBK1 and IKK-ɛ similarly activated?
- Aspirin inhibits IKK-β-mediated prostate cancer cell invasion by targeting matrix metalloproteinase-9 and urokinase-type plasminogen activator
- Association of a Network of Interferon-Stimulated Genes with a Locus Encoding a Negative Regulator of Non-conventional IKK Kinases and IFNB1
- Association of the adaptor TANK with the IκB kinase (IKK) regulator NEMO connects IKK complexes with IKKε and TBK1 kinases
- Astragaloside IV facilitates glucose transport in C2C12 myotubes through the IRS1/AKT pathway and suppresses the palmitate-induced activation of the IKK …
- ATM is required for IκB kinase (IKK) activation in response to DNA double strand breaks
- ATM-and NEMO-dependent ELKS ubiquitination coordinates TAK1-mediated IKK activation in response to genotoxic stress
- ATM-dependent nuclear accumulation of IKK-α plays an important role in the regulation of p73-mediated apoptosis in response to cisplatin
- ATP alters IKK-2 inhibitor affinity for IKK2 enzyme and reveals non-equivalent inhibitor binding sites
- ATS Abstract: IKK-ß Is Required For Rhinovirus Induced IFN-ß, IFN-» And Pro-inflammatory Cytokine Production In Vitro And In Vivo
- Atypical forms of incontinentia pigmenti in male individuals result from mutations of a cytosine tract in exon 10 of NEMO (IKK-γ)
- Aurora and IKK kinases cooperatively interact to protect multiple myeloma cells from Apo2L/TRAIL
- Autophagy protects intestinal epithelial cells against deoxynivalenol toxicity by alleviating oxidative stress via IKK signaling pathway
- BAG3 is required for IKK α nuclear translocation and emergence of castration resistant prostate cancer
- Bcl3 phosphorylation by Akt, Erk2, and IKK is required for its transcriptional activity
- Benznidazole blocks NF-κB activation but not AP-1 through inhibition of IKK
- Benzoxathiolone LYR-64 inhibits NF-kB activation via IKK complexin LPS-stimuated macrophages RAW 264. 7
- Berberine suppresses in vitro migration and invasion of human SCC-4 tongue squamous cancer cells through the inhibitions of FAK, IKK, NF-κB, u-PA and MMP-2 and …
- Betafectin immunomodulator increases the activities of JNK and IKK kinases and increases the nuclear translocation of AP-1 in macrophage cells.
- BIOCHEMICAL CHARACTERIZATION OF SUPPRESSOR OF IKK-ε AND NAK-ASSOCIATED PROTEIN 1
- Biochemical Properties of IKK and Bcl3
- Bioinformatics Predictions of IKK Related Proteins Binding Long Non-Coding RNAs
- Biologic sequelae of IκB kinase (IKK) inhibition in multiple myeloma: therapeutic implications
- Biomechanical signals inhibit IKK activity to attenuate NF‐κB transcription activity in inflamed chondrocytes
- Bortezomib Increases IL-8 Expression in Ovarian Cancer Cells Through IKK and EGR-1 Pathways
- Brazilin selectively disrupts proximal IL-1 receptor signaling complex formation by targeting an IKK-upstream signaling components
- Breaking resistance of pancreatic cancer cells to an attenuated vesicular stomatitis virus through a novel activity of IKK inhibitor TPCA-1
- C-Terminal Serine Rich Region of IKK– Interacts with Bfl-1, a Homologue of Bcl-2
- C70 THE NEXT NEW THERAPEUTIC TARGET? TRANSLATIONAL STUDIES OF COPD THERAPIES: The Effect Of An Ikgr; b-Kinase-[Beta](IKK [Beta]) Inhibitor On …
- Ca2+/calmodulin-dependent protein phosphatase calcineurin mediates the expression of iNOS through IKK and NF-κB activity in LPS-stimulated mouse peritoneal …
- Caffeic acid regulates LPS-induced NF-κB activation through NIK/IKK and c-Src/ERK signaling pathways in endothelial cells
- Cardiomyocyte-specific IκB kinase (IKK)/NF-κB activation induces reversible inflammatory cardiomyopathy and heart failure
- Carnosic acid modulates Akt/IKK/NF-κB signaling by PP2A and induces intrinsic and extrinsic pathway mediated apoptosis in human prostate carcinoma PC-3 cells
- CD147 promotes IKK/IκB/NF-κB pathway to resist TNF-induced apoptosis in rheumatoid arthritis synovial fibroblasts
- CFC replacement in the focus of attention at the IKK’91 in Essen. IKK 91 in Essen im Zeichen der FCKW-Substitution
- Characterization of the bovine IκB kinases (IKK) α and IKKβ, the regulatory subunit NEMO and their substrate IκBα
- Characterization of the IKK Signaling Complex
- Characterization of the inhibitor of kappaB kinase (IKK) complex in granulosa cell tumors of the ovary and granulosa cell tumor-derived cell lines
- Chemosensitization in non‐small cell lung cancer cells by IKK inhibitor occurs via NF‐κB and mitochondrial cytochrome c cascade
- Chlamydia pneumoniae activates IKK/IκB-mediated signaling, which is inhibited by 4-HNE and following primary exposure
- Chronic alcohol exposure exacerbates inflammation and triggers pancreatic acinar-to-ductal metaplasia through PI3K/Akt/IKK
- cIAP2 negatively regulates proliferation and tumourigenesis by repressing IKK activity and maintaining p53 function
- Ciglitazone ameliorates lung inflammation by modulating the IKK/NF-κB pathway following hemorrhagic shock
- CIGLITAZONE REDUCES NF-κB ACTIVITY BY INHIBITING IKK IN HEMORRHAGIC SHOCK.: 58
- Cis-guggulsterone inhibits the IKK/NF-κB pathway, whereas trans-guggulsterone inhibits MAPK/AP-1 in MCF‑7 breast cancer cells: Guggulsterone regulates …
- CITED2 modulates metastatic ability through effects on IKK-alpha in breast cancer cells
- Classical NF-κB activation impairs skeletal muscle oxidative phenotype by reducing IKK-α expression
- Clinical study on the relationship between the activation of the IKK-IκB-NFκB pathway and insulin resistance
- Cloning and characterization of an IKK homologue from pearl oyster, Pinctada fucata
- Clostridium difficile toxin A promotes dendritic cell maturation and chemokine CXCL2 expression through p38, IKK, and the NF-κB signaling pathway
- Coexpression of proangiogenic factors IL-8 and VEGF by human head and neck squamous cell carcinoma involves coactivation by MEK-MAPK and IKK-NF-κB signal …
- Coincident enrichment of phosphorylated IκBα, activated IKK, and phosphorylated p65 in the axon initial segment of neurons
- Collagen and prostaglandin E2 regulate aromatase expression through the PI3K/AKT/IKK and the MAP kinase pathways in adipose stromal cells
- Combined use of pharmacokinetic modeling and a steady-state delivery approach allows early assessment of IκB kinase-2 (IKK-2) target safety and efficacy
- Complete Reconstitution of Human IκB Kinase (IKK) Complex in Yeast ASSESSMENT OF ITS STOICHIOMETRY AND THE ROLE OF IKKγ ON THE COMPLEX …
- Compound FLZ inhibits lipopolysaccharide-induced inflammatory effects via down-regulation of the TAK-IKK and TAK-JNK/p38MAPK pathways in RAW264. 7 …
- Comprehending the complex connection between PKCβ, TAK1, and IKK in BCR signaling
- Compressive mechanical stress may activate IKK-NF-κB through proinflammatory cytokines in MC3T3-E1 cells
- Conjugated linoleic acids produced by Lactobacillus dissociates IKK-γ and Hsp90 complex in Helicobacter pylori-infected gastric epithelial cells
- Connecting inflammation and cancer through the IKK-NF-κB nexus
- Constitutive Activation of NF-kappaB in Prostate Carcinoma Cells Through a Positive Feedback Loop: Implication of Inducible IKK-Related Kinase (IKKi)
- Constitutive Activation of NF-Kb in Prostate Carcinoma Cells through a Positive Feedback Loop: Implication of Inducible IKK-Related Kinase (IKKi)
- Constitutive activation of TAK1 by HTLV-1 tax-dependent overexpression of TAB2 induces activation of JNK-ATF2 but not IKK-NF-κB
- Constitutive and interleukin-1-inducible phosphorylation of p65 NF-κB at serine 536 is mediated by multiple protein kinases including IκB kinase (IKK)-α, IKKβ, IKKϵ …
- Context-dependent regulation of autophagy by IKK-NF-κB signaling: Impact on the aging process
- Control of canonical NF-κB activation through the NIK–IKK complex pathway
- Control of osteoclast activity and bone loss by IKK subunits: new targets for therapy
- Coordination of the canonical and noncanonical IKK/NF-κB signaling pathways in HTLV-I tax-mediated tumorigenesis
- Correlation between the signal pathway IKK/NF-? B and the anti-oxidant activity in asthma rats and the modulation of Ginkgo biloba extract
- Counter-regulation in the IKK family
- Crosstalk between the NF‐κB activating IKK‐complex and the CSN signalosome
- Crystal structure of a vFlip-IKKγ complex: insights into viral activation of the IKK signalosome
- Curcumin dually inhibits both mTOR and NF-κB pathways through a crossed PI3K/Akt/IKK signaling axis in adenoid cystic carcinoma
- Curcumin Treatment Suppresses IKK Kinase Activity of Salivary Cells of Patients with Head and Neck Cancer: A Pilot Study
- Cutting edge: the IκB kinase (IKK) inhibitor, NEMO-binding domain peptide, blocks inflammatory injury in murine colitis
- Cytokine receptor signaling activates an IKK-dependent phosphorylation of PUMA to prevent cell death
- Cytosolic Hsp60 is involved in the NF-κB-dependent survival of cancer cells via IKK regulation
- Cytotoxic Necrotizing Factor 1 Prevents Apoptosis via the AKT/IKK pathway: Role of NF-κB and Bcl-2
- Daphnetin inhibits TNF‐α and VEGF‐induced angiogenesis through inhibition of the IKK s/IκBα/NF‐κB, Src/FAK/ERK 1/2 and Akt signalling pathways
- Davallia bilabiata Inhibits TNF-α-Induced Adhesion Molecules and Chemokines by Suppressing IKK/NF-kappa B Pathway in Vascular Endothelial Cells
- Dbl and the Rho GTPases activate NFκB by IκB kinase (IKK)-dependent and IKK-independent pathways
- De-ubiquitylation is the most critical step in the ubiquitin-mediated homeostatic control of the NF-jB/IKK basal activity
- De-ubiquitylation is the most critical step in the ubiquitin-mediated homeostatic control of the NF-κB/IKK basal activity
- Deactivation of the kinase IKK by CUEDC2 through recruitment of the phosphatase PP1
- Decreased IKK Signaling in Skeletal Muscle of Patients with Hyperglycemic Crisis.
- Deficient natural killer cell cytotoxicity in patients with IKK-γ/NEMO mutations
- Design and preparation of 2-benzamido-pyrimidines as inhibitors of IKK
- determine distinct IKK α Pleiotropic functions of TNF
- Dextran-g-lauric acid as IKK complex inhibitor carrier
- Differential IKK/NF-kB Activity Is Mediated by TSC2 through mTORC1 in PTEN-Null Prostate Cancer and Tuberous Sclerosis Complex Tumor Cells
- Differential IKK/NF-κB activity is mediated by TSC2 through mTORC1 in PTEN-null prostate cancer and tuberous sclerosis complex tumor cells
- Differential Requirement for the IKK
- Direct Phosphorylation of I kappa B by IKK [small alpha, Greek] and IKK [small beta, Greek]: Discrimination Between Free and NF-kappa B-Bound Substrate
- Direct, noncatalytic mechanism of IKK inhibition by A20
- Discovery of 6-Aryl-7-alkoxyisoquinoline Inhibitors of IκB Kinase-β (IKK-β)
- Discovery of 6-aryl-azabenzimidaoles that inhibit the TBK1/IKK-ε kinases
- Discovery of a novel IKK-β inhibitor by ligand-based virtual screening techniques
- Discovery of novel and selective IKK-β serine-threonine protein kinase inhibitors. Part 1
- DISCOVERY OF NOVEL IKK-Β INHIBITOR BY STRUCTURAL MODIFICATIONS OF CHLORPROPAMIDE AND NATEGLINIDE
- Discovery of novel potent nuclear factor kappa‐B inhibitors (IKK‐β) via extensive ligand‐based modeling and virtual screening
- Discovery of piperidinyl aminopyrimidine derivatives as IKK-2 inhibitors
- Disrupting the inhibitory Kappa B kinase (IKK)-Aurora A axis in cancer
- Disruption of IκB kinase (IKK)-mediated RelA serine 536 phosphorylation sensitizes human multiple myeloma cells to histone deacetylase (HDAC) inhibitors
- Distinct activation mechanisms of NF-κB regulator inhibitor of NF-κB kinase (IKK) by isoforms of the cell death regulator cellular FLICE-like inhibitory protein (cFLIP)
- Distinct B subunits of PP 2A regulate the NF‐κB signalling pathway through dephosphorylation of IKK β, IκBα and RelA
- Distinct roles for JNK and IKK activation in agouti-related peptide neurons in the development of obesity and insulin resistance
- Diversity oriented synthesis and IKK inhibition of aminobenzimidazole tethered quinazoline-2, 4-diones, thioxoquinazolin-4-ones, benzodiazepine-2, 3, 5-triones …
- DMA, a Bisbenzimidazole, Offers Radioprotection by Promoting NFκB Transactivation through NIK/IKK in Human Glioma Cells
- Docosahexaenoic acid inhibition of inflammation is partially via cross-talk between Nrf2/heme oxygenase 1 and IKK/NF-κB pathways
- Domain-specific interaction with the IκB kinase (IKK) regulatory subunit IKKγ is an essential step in Tax-mediated activation of IKK
- Drosophila IKK-related kinase Ik2 and Katanin p60-like 1 regulate dendrite pruning of sensory neuron during metamorphosis
- Drosophila IKK-related kinase regulates nonapoptotic function of caspases via degradation of IAPs
- Dynamic Characterization of the IKK: κBα: NFκB Negative Feedback Loop Using Real-Time Bioluminescence Imaging
- Dynamic interaction of stress granules, DDX3X, and IKK-α mediates multiple functions in hepatitis C virus infection
- E1A inhibition of radiation-induced NF-κB activity through suppression of IKK activity and IκB degradation, independent of Akt activation
- Effect and mechanism of IKK-2 receptor blocker on corneal stromal fibroblasts
- Effect and significance of anisodamine on I-kappaB kinase (IKK) in traumatic lung injury
- Effect of Collaterals-smoothing Drugs on Expressions of IκB-a and IKK-a in Sciatic Nerve of Diabetic Rats
- Effect of FK506 and Cyclosporin A on IκBα Degradation and IKK Pathway in Bronchial Epithelial Cells, Monocytes, Lymphocytes and Alveolar Macrophages
- Effect of IKK-2 Inhibitor on Local Th1 and Th2 Type Inflammation
- Effect of IKK-beta specific inhibitor PS1145 on NF-kappaB activity and apoptosis in prostate carcinoma cell lines
- Effect of Kuijieling decoction on proteins expression of IKK-alpha in colonic mucosa of ulcerative colitis model rats
- Effect of Rosiglitazone on Insulin Resistance and ROS. IKK Signaling Pathway in Vascular Endothelial Cells
- Effect of rosiglitazone on phosphorylation IKK and IκBα in the Heart of STZ Diabetic Rats [J]
- Effective suppression of pro‐inflammatory molecules by DHCA via IKK‐NF‐κB pathway, in vitro and in vivo
- Effects of a brief high-fat diet and acute exercise on the mTORC1 and IKK/NF-κB pathways in rat skeletal muscle
- Effects of IKK inhibitor PS1145 on NF-κ B function, proliferation, apoptosis and invasion activity in prostate carcinoma cells
- Effects of P-MAPA immunomodulator on Toll-like receptor 2, ROS, nitric oxide, MAPKp38 and IKK in PBMC and macrophages from dogs with visceral leishmaniasis
- Effects of Soothing Liver and Invigorating Spleen Recipes on the IKK-NF-B Signaling Pathway in Kupffer Cells of Nonalcoholic Steatohepatitis Rats
- Effects of TCDD upon IκB and IKK subunits localized in microsomes by proteomics
- El BUSINESS If IKK
- Embryonic lethality, liver degeneration, and impaired NF-κB activation in IKK-β-deficient mice
- EMMPRIN activates multiple transcription factors in cardiomyocytes, and induces interleukin-18 expression via Rac1-dependent PI3K/Akt/IKK/NF-κB andMKK7/JNK …
- Endothelial cell injury and dysfunction induced by silver nanoparticles through oxidative stress via IKK/NF-κB pathways
- Endothelial IKK β Signaling is Required for Monocyte Adhesion under Laminar Flow Conditions
- Endothelial-specific Deletion of Inhibitor of Kappa-B Kinase-β (IKK-β)
- Energy calibration of the IKK fast chopper with 238U standards
- Epithelial-cell-intrinsic IKK-β expression regulates intestinal immune homeostasis
- Epstein-Barr virus-encoded EBNA1 inhibits the canonical NF-κB pathway in carcinoma cells by inhibiting IKK phosphorylation
- Epstein–Barr virus-encoded latent infection membrane protein 1 regulates the processing of p100 NF-κ B2 to p52 via an IKK γ/NEMO-independent signalling …
- ER stress activates NF-κB by integrating functions of basal IKK activity, IRE1 and PERK
- ERK is an anti-inflammatory signal that suppresses expression of NF-κB-dependent inflammatory genes by inhibiting IKK activity in endothelial cells
- Erratum to” Discovery of novel and selective IKK-b serine-threonine protein kinase inhibitors. Part 1″-(Bioorg. Med. Chem. Lett. 13 (2003) 913)
- Etanercept Reverses Downregulation of Inhibitor of Nuclear Factor Kappa-B Kinase Subunit Alpha (IKK [alpha]) in Psoriasis
- Evidence that TNF-TNFR1-TRADD-TRAF2-RIP-TAK1-IKK pathway mediates constitutive NF-κ B activation and proliferation in human head and neck …
- Exclusion from the Golgi and very low levels of HTLV-2 Tax ubiquitination do not prevent IKK-gamma/NEMO relocalization and NF-B activation
- Exclusion from the Golgi and very low levels of HTLV-2 Tax ubiquitination do not prevent IKK-gamma/NEMO relocalization and NF-κB activation
- Exploring Suppressor of IKK Epsilon’s Interaction with Cytoskeletal Proteins
- Expression and function of NIK‐and IKK 2‐binding protein (NIBP) in mouse enteric nervous system
- Expression and regulation of inducible IκB kinase (IKK-i) in human fibroblast-like synoviocytes
- Expression, purification and functional characterization of IκB kinase-2 (IKK-2) mutants
- Faculty, IKK
- FAF1 suppresses IκB kinase (IKK) activation by disrupting the IKK complex assembly
- Falcarindiol impairs the expression of inducible nitric oxide synthase by abrogating the activation of IKK and JAK in rat primary astrocytes
- Fanconi anemia protein complex is a novel target of the IKK signalsome
- Feed-forward signaling of TNF-α and NF-κB via IKK-β pathway contributes to insulin resistance and coronary arteriolar dysfunction in type 2 diabetic mice
- Fentanyl Suppresses the Survival of CD4+ T Cells Isolated from Human Umbilical Cord Blood through Inhibition of IKKs‐mediated NF‐κB Activation
- fibrosis) at 28-days post reperfusion, which was markedly reduced by the late administration of IKK16. Conclusion: The late inhibition of IKK may, therefore, have …
- Flavokawain B, the hepatotoxic constituent from kava root, induces GSH-sensitive oxidative stress through modulation of IKK/NF-κB and MAPK signaling pathways
- Fluticasone reduces IL-6 and IL-8 production of cystic fibrosis bronchial epithelial cells via IKK-β kinase pathway
- FOXO 3 as a new IKK‐ε‐controlled check‐point of regulation of IFN‐β expression
- FoxO transcription factor is delocalized in CML patients by Bcr-Abl induced PI3K/AKT activation and IKK pathway and can be reactivated by Imatinib treatment
- FoxO Transcription Factor Is Delocalized in CML Patients by Bcr-Abl Induced PI3K/AKT Activation and IKK Pathway and Can Be Reactivated by Imatinib Treatment.
- Functional analysis of astroglial IKK/NF-KappaB signaling in brain development and homeostasis
- Functional Role of c-Src in IL-1–Induced NF-κB Activation: c-Src Is a Component of the IKK Complex
- GD2+ breast cancer stem cell growth is dependent on NFκB signaling and suppressed by the IKK inhibitor BMS345541 in vitro and in vivo
- Genistein sensitizes bladder cancer cells to HCPT treatment in vitro and in vivo via ATM/NF-κB/IKK pathway-induced apoptosis
- Ghrelin Suppression of Helicobacter pylori-Induced Gastric Mucosal Expression of iNOS is Mediated through the Inhibition of IKK-β Activation by cNOS …
- Gold compound auranofin inhibits IκB kinase (IKK) by modifying Cys-179 of IKKβ subunit
- GPx-1 Gene Delivery Modulates NFκB Activation Following Diverse Environmental Injuries Through a Specific Subunit of the IKK Complex
- GW26-e1432 Effect of Rosiglitazone on Insulin Resistance and ROS/IKK Signaling Pathway in Vascular Endothelial Cells
- GW26-e2212 Effect of Atorvastatin on IKK/NF-кB Pathway of Insulin Resistance in Vascular Endothelial Cells
- GW27-e0848 Effect of Celastrol on Insulin Resistance and ROS/IKK Signaling Pathway in Vascular Endothelial Cells
- H-RN, a novel antiangiogenic peptide derived from hepatocyte growth factor inhibits inflammation in vitro and in vivo through PI3K/AKT/IKK/NF-κB signal pathway
- hCINAP negatively regulates NF-κB signaling by recruiting the phosphatase PP1 to deactivate IKK complex
- HDAC/IKK inhibition therapies in solid tumors.
- Heat shock treatment suppresses angiotensin II-induced activation of NF-κB pathway and heart inflammation: a role for IKK depletion by heat shock?
- Hematopoietic progenitor kinase-1 (HPK1) stress response signaling pathway activates IκB kinases (IKK-α/β) and IKK-β is a developmentally regulated …
- Hepatic activation of IKK/NFκB signaling induces liver fibrosis via macrophage‐mediated chronic inflammation
- Hepatitis C virus infection activates an innate pathway involving IKK-α in lipogenesis and viral assembly
- Hepatocyte-specific IKK-β activation enhances VLDL-triglyceride production in APOE* 3-Leiden mice
- Hepatoprotective effect of quercetin against LPS/d-GalN induced acute liver injury in mice by inhibiting the IKK/NF-κB and MAPK signal pathways
- High glucose-induced IKK-Hsp-90 interaction contributes to endothelial dysfunction
- Hijacking of host cell IKK signalosomes by the transforming parasite Theileria
- Histone deacetylase (HDAC) inhibition induces IκB kinase (IKK)-dependent interleukin-8/CXCL8 expression in ovarian cancer cells
- Histone H3 phosphorylation by IKK-α is critical for cytokine-induced gene expression
- Hit Identification of IKK-beta Natural Product Inhibitor
- Hit-to-lead studies: the discovery of potent, orally active, thiophenecarboxamide IKK-2 inhibitors
- Honokiol ameliorates endothelial dysfunction through suppression of PTX3 expression, a key mediator of IKK/IκB/NF-κB, in atherosclerotic cell model
- Honokiol inhibits TNF-α-stimulated NF-κB activation and NF-κB-regulated gene expression through suppression of IKK activation
- Host and parasite-derived IKK activities direct distinct temporal phases of NF-κB activation and target gene expression following Toxoplasma gondii infection
- How NF-κB is activated: the role of the IκB kinase (IKK) complex
- HSP27 regulates IL-1 stimulated IKK activation through interacting with TRAF6 and affecting its ubiquitination
- Hsp90 inhibition results in autophagy-mediated proteasome-independent degradation of IκB kinase (IKK)
- HTLV-1 tax functions as a ubiquitin E3 ligase for direct IKK activation via synthesis of mixed-linkage polyubiquitin chains
- HTLV-1 tax induces formation of the active macromolecular IKK complex by generating Lys63-and Met1-linked hybrid polyubiquitin chains
- HTLV-1 Tax protein induces autophagy via IKK in human astroglioma cells: a protective mechanism against death receptor-mediated apoptosis (610.1)
- HTLV-1 Tax stimulates ubiquitin E3 ligase, ring finger protein 8, to assemble lysine 63-linked polyubiquitin chains for TAK1 and IKK activation
- Hyaluronan induces MMP-9 secretion through FAK-IKK/IκBα pathways and 17-AAG down-regulates these pathways in human glioma cells
- Hydrogen peroxide has opposing effects on IKK activity and I κ B α breakdown in airway epithelial cells
- Hyper activation of β‐catenin signalling induced by IKK ε inhibition thwarts colorectal cancer cell proliferation
- Hypothalamic programming of systemic ageing involving IKK-β, NF-κB and GnRH
- Hypoxia activates IKK–NF-κB and the immune response in Drosophila melanogaster
- I-kappa-kinase-2 (IKK-2) inhibition potentiates vincristine cytotoxicity in non-Hodgkin’s lymphoma
- Icariin attenuates lipopolysaccharide-induced microglial activation and resultant death of neurons by inhibiting TAK1/IKK/NF-κB and JNK/p38 MAPK pathways
- Identification of Human IKK-2 Inhibitors of Natural Origin (Part I): Modeling of the
- Identification of human IKK-2 inhibitors of natural origin (part I): modeling of the IKK-2 kinase domain, virtual screening and activity assays
- Identification of human IKK-2 inhibitors of natural origin (Part II): in Silico prediction of IKK-2 inhibitors in natural extracts with known anti-inflammatory activity
- Identification of mutations in TRAPPC9, which encodes the NIK-and IKK-β-binding protein, in nonsyndromic autosomal-recessive mental retardation
- IDENTIFICATION OF NOVEL SUBSTRATE I-TRAF OF IKK-i KINASE
- Identification of plumericin from Himatanthus Sucuuba as a novel potent inhibitor of the NF-κB pathway directly targeting IKK-β
- IFIT5 positively regulates NF-κB signaling through synergizing the recruitment of IκB kinase (IKK) to TGF-β-activated kinase 1 (TAK1)
- IKK Alfred, Crosby-house, 95, Bishopsgate-street
- IKK alpha coordinates with RAS to switch well-differentiated papillomas to poorly differentiated malignant carcinomas in skin
- IKK alpha induces angiogenesis
- IKK alpha play an inhibitory role in malignant skin tumor progression
- IKK and (Beta)-Catenin in Breast Cancer
- IKK and Caspases in Regulating Cell Shape
- IKK and Diabetic Nephropathy [J]
- IKK and NF‐κB‐mediated regulation of Claspin impacts on ATR checkpoint function
- IKK antagonizes activation-induced cell death of CD4+ T cells in aged mice via inhibition of JNK activation
- IKK antagonizes CD95 ligation-mediated apoptosis by regulating NF-κB activity
- IKK at the 580 revolutions the “down” run was made
- IKK biology
- IKK Capt. Gabriel J., 6, Belsize-park, Hampstead
- IKK Charles Henry, 51, King’s-road, Camden-town
- IKK connects autophagy to major stress pathways
- IKK cuts both ways in Huntington’s disease
- IKK Electric F40LW-RS-WMII at approximately 1000
- IKK epsilon Deficiency Exacerbates Inflammation in the Absence of an Interferon Response in Murine Arthritis by Delaying Neutrophil Apoptosis
- IKK epsilon kinase is crucial for viral G protein-coupled receptor tumorigenesis
- IKK epsilon, STAT1, and IFIT2 define a novel innate immune effector pathway against West Nile virus infection
- IKK exceptional, viz. the temperature high and the air
- IKK expression as an immunohistochemical marker for diagnosis of high risk flat epithelial atypia (FEA) of the breast
- IKK Goes BAD
- IKK have not saved, and to bury them when
- IKK Henry Charles, 86, South-hill-park, Hampstead
- IKK inhibition by BMS-345541 suppresses breast tumorigenesis and metastases by targeting GD2+ cancer stem cells
- IKK inhibition increases bortezomib effectiveness in ovarian cancer
- IKK inhibition prevents PM2. 5-exacerbated cardiac injury in mice with type 2 diabetes
- IKK inhibitor PS1145 increases sensitivity of pancreatic cancer cells to TRAIL-induced apoptosis.
- IKK inhibitor suppresses epithelial-mesenchymal transition and induces cell death in prostate cancer
- IKK inhibitory activities of imidazo [1, 2-a] pyrazine, imidazo [1, 2-a] quinoxaline, imidazo [1, 5-a] quinoxaline and pyrazolo [1, 5-a] quinoxaline derivatives.
- IKK interacts with rictor and regulates mTORC2
- IKK is a therapeutic target in KRAS-induced lung cancer with disrupted p53 activity
- IKK jar of the previous dayforgiven, if not for
- IKK kinase assay for assessment of canonical NF-κB activation in neurons
- IKK Links the Steroid Receptor Coactivator to Immune Responses
- IKK low much or how little it surprised
- IKK M.-What is memory aging the aging of? Developmental Psychology. 1978, 14
- IKK mediates ischemia-induced neuronal death
- IKK my passage-money is more than I can
- IKK NBD peptide inhibits LPS induced pulmonary inflammation and alters sphingolipid metabolism in a murine model
- IKK of ease, and little alle
- IKK phosphorylates Huntingtin and targets it for degradation by the proteasome and lysosome
- IKK phosphorylates RelB to modulate its promoter specificity and promote fibroblast migration downstream of TNF receptors
- IKK phosphorylation of NF-κB at serine 536 contributes to acquired cisplatin resistance in head and neck squamous cell cancer
- IKK Phosphorylation, ICAM–1, and CD11a/LFA–1 Increases Are Correlated With VEGF–Induced Blood–Retinal Barrier Breakdown and Are Blocked by Triamcinolone …
- IKK Proverb,” that he who i
- IKK regulates the deubiquitinase CYLD at the postsynaptic density
- IKK regulation and human genetics
- IKK results are included AAAAA
- IKK SCienCe
- IKK Targets PI3K
- IKK that the fact was not suspected in his life
- IKK the night and the morrow in that disa
- IKK The North Central High School, Spökano
- IKK to British subjects, residing at Zan
- IKK to us, nor could it have influenced our
- IKK were entitled to protection against this system of
- IKK with ebonite is shown in the following
- IKK with Mr. E, Jones, Hibernian Schools, Liver.
- IKK yearly by government auditor, and pub
- IKK α represses a network of inflammation and proliferation pathways and elevates c-Myc antagonists and differentiation in a dose-dependent manner in the …
- IKK β in postnatal perichondrium remotely controls endochondral ossification of the growth plate through downregulation of MCP-5
- IKK β inhibitor identification: a multi-filter driven novel scaffold
- IKK β programs to turn on the GADD45α/MKK4/JNKs apoptotic cascade specifically via p50 NF-κB in arsenite response
- IKK β regulates endothelial thrombomodulin in a Klf2‐dependent manner
- IKK β-targeted anti-inflammatory activities of a butanol fraction of artificially cultivated Cordyceps pruinosa fruit bodies
- IKK-±: An Alternative Player In Inflammation-Induced Loss Of Muscle Oxidative Phenotype In COPD?
- IKK-1 and IKK-2: cytokine-activated IκB kinases essential for NF-κB activation
- IKK-2
- IKK-2 inhibitor TPCA-1 represses nasal epithelial inflammation in vitro.
- IKK-2 is required for TNF-α-induced invasion and proliferation of human mesenchymal stem cells
- IKK-2/NF-κB-DEPENDENT TRANSCRIPTION
- IKK-alpha PROTEIN, NUCLEIC ACID ENCODING THE SAME AND METHOD
- IKK-and NF-κB-mediated functions in carcinogenesis
- IKK-Beta Deletion Alleviates the Atherogenetic Effect of Intermittent Hypoxia Induced Macrophage Foam Cell Formation
- IKK-dependent activation of NF-κB contributes to myeloid and lymphoid leukemogenesis by BCR-ABL1
- IKK-dependent, NF-κB-independent control of autophagic gene expression
- IKK-epsilon contributes to the malignant progression of ovarian cancer
- IKK-Epsilon, a novel factor identified by proteomics, contributes to prostate cancer cell-induced osteoclast activity in vitro.
- IKK-i and TBK-1 are Enzymatically Distinct from the Homologous Enzyme IKK-2 COMPARATIVE ANALYSIS OF RECOMBINANT HUMAN IKK-i, TBK-1, AND IKK-2
- IKK-i signals through IRF3 and NFκB to mediate the production of inflammatory cytokines
- IKK-i, a novel lipopolysaccharide-inducible kinase that is related to IκB kinases
- IKK-i/IKKϵ controls constitutive, cancer cell-associated NF-κB activity via regulation of Ser-536 p65/RelA phosphorylation
- IKK-IKB-NF-kB gene manipulations and polymorphisms in relation to susceptibility to different diseases
- IKK-induced NF-κB1 p105 proteolysis is critical for B cell antibody responses to T cell–dependent antigen
- IKK-mediated signaling controls prostate tumor initiating cells
- IKK-NBD peptides exert anti-inflammation effect in rats after focal cerebral cortex ischemia/reperfusion via regulating c-rel [J]
- IKK-related genetic diseases: probing NF-κB functions in humans and other matters
- IKK-β inhibitors: An analysis of drug–receptor interaction by using Molecular Docking and Pharmacophore 3D-QSAR approaches
- IKK-β links inflammation to obesity-induced insulin resistance
- IKK-β mediates chemoresistance by sequestering FOXO3; a critical factor for cell survival and death
- IKK-β mediates hydrogen peroxide induced cell death through p85 S6K1
- IKK-β Recombinant Adenovirus
- IKK-β/NF-κB p65 mediates p27Kip1 protein degradation in arsenite response
- IKK-γ is an essential regulatory subunit of the IκB kinase complex
- IKK-γ, GST-tagged, human recombinant, expressed in Sf9 cells
- IKK-ε coordinates invasion and metastasis of ovarian cancer
- IKK‐β‐mediated myeloid cell activation exacerbates inflammation and inhibits recovery after spinal cord injury
- IKK? and synovial inflammation
- IKK? is key to induction of insulin resistance in the hypothalamus, and its inhibition reverses obesity
- IKK/NF-kappaB serving as essential components of the MAP kinase signal transduction pathway.
- IKK/NF-κB activation is essential for Helicobacter pylori-induced chronic gastritis in Mongolian gerbils
- IKK/NF-κB regulates skeletal myogenesis via a signaling switch to inhibit differentiation and promote mitochondrial biogenesis
- IKK/NF-κB regulates skeletal myogenesis via a signaling switch to inhibit differentiation and promote mitochondrial biogenesis
- IKK/NF-κB signaling contributes to glioblastoma stem cell maintenance
- IKK/NF-κB signaling in intestinal epithelial cells controls immune homeostasis in the gut
- IKK/NF-κB signaling pathway inhibits cell-cycle progression by a novel Rb-independent suppression system for E2F transcription factors
- IKK/NF-κB signaling: balancing life and death–a new approach to cancer therapy
- IKK/NF-κB system protects from Hepatitis B surface antigen-induced hepatocarcinogenesis
- IKK/NF-κB/Rel in Acute Pancreatitis and Pancreatic Cancer: Torments of Tantalus
- IKK/NF‐κB and STAT3 pathways: central signalling hubs in inflammation‐mediated tumour promotion and metastasis
- IKK/nuclear factor-kappaB and oncogenesis: roles in tumor-initiating cells and in the tumor microenvironment
- IKKα is required for the homeostasis of regulatory T cells and for the expansion of both regulatory and effector CD4 T cells
- IKKγ serves as a docking subunit of the IκB kinase (IKK) and mediates interaction of IKK with the human T-cell leukemia virus Tax protein
- Improved Intraportal Islet Transplantation Outcome by Systemic IKK‐beta Inhibition: NF‐κB Activity in Pancreatic Islets Depends on Oxygen Availability
- in vivo Cardiac Gene Transfer of Dominant Negative IKK-beta Reduces Myocardial Inflammation, Apoptosis, and Infarction after Ischemia-Reperfusion Injury
- In Vivo Cardioprotection by Pitavastatin From Ischemic-reperfusion Injury Through Suppression of IKK/NF-κB and Upregulation of pAkt–e-NOS
- In Vivoandin VitroRecruitment of an IκBα-Ubiquitin Ligase to IκBα Phosphorylated by IKK, Leading to Ubiquitination
- Inactivation of BAD by IKK inhibits TNFα-induced apoptosis independently of NF-κB activation
- Inactivation of Bcl‐2 through IκB kinase (IKK)‐dependent phosphorylation mediates apoptosis upon exposure to 4‐hydroxynonenal (HNE)
- Indacaterol inhibits tumor cell invasiveness and MMP-9 expression by suppressing IKK/NF-κB activation
- Induction in gastric mucosal prostaglandin and nitric oxide by Helicobacter pylori is dependent on MAPK/ERK-mediated activation of IKK-β and cPLA2: modulatory …
- Induction of proinflammatory mediators requires activation of the TRAF, NIK, IKK and NF‐κB signal transduction pathway in astrocytes infected with Escherichia coli
- Inflammation and the IKK β/I κ B/NF-κ B axis in obesity-and diet-induced insulin resistance
- Influence of low level and long-term arsenic exposure to the phosphorylated protein kinase B as well as its downstream signal factor IKK, I-ΚB and NF-κB in HaCat …
- Influence of oleanolic acid pretreatment to the IKK/I-κB/NF-κB signaling pathway during rat’s HIRI [J]
- Influence of rosuvastatin calcium and telmisartan on the expressions of IKK, ROS of insulin resistance rat liver
- Influenza A virus‐encoded NS 1 virulence factor protein inhibits innate immune response by targeting IKK
- Information and communication platform for crisis management (IKK)
- Inhibition of canonical IKK/NF-kB signaling in Hepatitis B Virus surface antigen transgenic mice drastically increases HCC development due to dysregulated Unfolded …
- Inhibition of choriodecidual cytokine production and inflammatory gene expression by selective I‐κB kinase (IKK) inhibitors
- Inhibition of cyclo-oxygenase 2 expression in colon cells by the chemopreventive agent curcumin involves inhibition of NF-κB activation via the NIK/IKK …
- Inhibition of herpesvirus-induced HIV-1 replication by cyclopentenone prostaglandins: role of IκB kinase (IKK)
- Inhibition of ICAM-1 gene expression, monocyte adhesion and cancer cell invasion by targeting IKK complex: molecular and functional study of novel α-methylene-γ …
- Inhibition of IKK [Beta] ReversesInsulin Resistance’in Cultured Cells
- Inhibition of IKK activation, through sequestering NEMO, blocks PMMA‐induced osteoclastogenesis and calvarial inflammatory osteolysis
- Inhibition of IKK activity enhances cell cycle arrest through p53-dependent p21Cip/WAF1 activation.
- Inhibition of IKK down‐regulates antigen+ IgE‐induced TNF production by mast cells: a role for the IKK‐IκB‐NF‐κB pathway in IgE‐dependent mast cell activation
- Inhibition of IKK-2 by 2-[(aminocarbonyl) amino]-5-acetylenyl-3-thiophenecarboxamides
- Inhibition of IKK-NFκB pathway sensitizes lung cancer cell lines to radiation
- Inhibition of IKK-β by epidioxysterols from the flowers of Calotropis gigantea (Niu jiao gua)
- Inhibition of IKK-β: A new development in the mechanism of the anti-obesity effects of PTP1B inhibitors SA18 and SA32
- Inhibition of IKK/NF-κB impairs glioma stem cell function
- Inhibition of IKK/NF-κB signaling enhances differentiation of mesenchymal stromal cells from human embryonic stem cells
- Inhibition of IL-6 Release in Vitro by in Vivo Administration of an IKK Inhibitor in Mice with Lung Fibrosis Induced by Poly I: C
- Inhibition of IκB kinase (IKK) protects against peripheral nerve dysfunction of experimental diabetes
- Inhibition of IκB phosphorylation by a novel IKK inhibitor IMD-1041 attenuates myocardial dysfunction after infarction
- Inhibition of IκB Phosphorylation by a Novel IKK Inhibitor IMD-1041 Attenuates Myocardial Dysfunction After Infarction
- Inhibition of NEMO, the regulatory subunit of the IKK complex, induces apoptosis in high-risk myelodysplastic syndrome and acute myeloid leukemia
- Inhibition of NF-κB activation by a novel IKK inhibitor reduces the severity of experimental autoimmune myocarditis via suppression of T-cell activation
- Inhibition of osteoblast functions by IKK/NF-κB in osteoporosis
- Inhibition of rosiglitazone on the expression of IKK-# beta# in the livers of rats with nonalcoholic steatohepatitis
- Inhibition of the canonical IKK/NFκB pathway sensitizes human cancer cells to doxorubicin
- Inhibition of the IKK pathway restores PI3-K activity in high-fat fed rodent skeletal muscles
- Inhibition of the IKK/NF-κB pathway by AAV gene transfer improves muscle regeneration in older mdx mice
- Inhibition of the IKK/NF-κB pathway impairs glioma stem cell function
- Inhibition of the NF-κ B survival pathway via caspase-dependent cleavage of the IKK complex scaffold protein and NF-κ B essential modulator NEMO
- Inhibition of type I interferon production via suppressing IKK-gamma expression: a new strategy for counteracting host antiviral defense by influenza A viruses?
- Inhibition of type I interferon-mediated antiviral action in human glioma cells by the IKK inhibitors BMS-345541 and TPCA-1
- Inhibitor-κB Kinase (IKK) β Regulates LPS-induced TNF-α Production in Cardiac Myocytes Through Modulation of NF-κB p65 Subunit Phosphorylation
- Innate immunity meets with cellular stress at the IKK complex: regulation of the IKK complex by HSP70 and HSP90
- Insulin exerts anti-inflammatory effects through reduction of IKK/IκB/NF-κB pathway activation in septic rats
- Insulin Receptor and IRS-1 Co-immunoprecipitation with SOCS-3, and IKK?/? Phosphorylation are Increased in Obese Zucker Rat Skeletal Muscle
- Insulin resistance, inflammation, and the IKK/IκB/NF-κB pathway
- Insulin/IGF-1 paradox of aging: regulation via AKT/IKK/NF-κB signaling
- Integrating cell-signalling pathways with NF-κB and IKK function
- Integration of TNF-a Signaling: Crosstalk between IKK, JNK, and Caspases
- Interaction of the TNFR-receptor associated factor TRAF1 with I-kappa B kinase 2 (IKK2, IKK-beta, IKBKB) and TRAF2 indicating a dose dependent regulatory …
- Interaction of vehicle and terrain results from 10 years research at IKK
- Interferon Regulatory Factors and the Atypical IKK-Related Kinases TBK1 and IKK-ε: Essential Players in the Innate Immune Response to RNA Virus Infection
- Interleukin-18 is a Potent Inducer of EMMPRIN Expression Both in vitro and in vivo, and Their Crosstalk Induces MMP9 Expression via PI3K-Akt-IKK-NF-κB …
- Intermittent hypoxia induces murine macrophage foam cell formation by IKK-β-dependent NF-κB pathway activation
- Interplay of IKK/NF-κB signaling in macrophages and myofibers promotes muscle degeneration in Duchenne muscular dystrophy
- Intestinal carcinogenesis: IKK can go all the way
- Intestinal epithelial cells release CXCL-2 in response to lipopolysaccharide via NF-KB and IKK activation
- Investigating IKK dynamics in the NF-κB signalling pathway using X-machines
- Investigation on constitutive IKK activity in the axon initial segment
- Involvement of cAMP-and IKK-2-Dependent Signal Pathways in the Growth Capacity of Mesenchymal Progenitor Cells under the Influence of Basic Fibroblast Growth …
- Involvement of the IκB kinase (IKK)-related kinases tank-binding kinase 1/IKKi and cullin-based ubiquitin ligases in IFN regulatory factor-3 degradation
- Involvement of the ubiquitin‐like domain of TBK1/IKK‐i kinases in regulation of IFN‐inducible genes
- Iron causes interactions of TAK1, p21ras and PI3K in caveolae to activate IKK in hepatic macrophages
- IκB kinase (IKK) β, but not IKKα, is a critical mediator of osteoclast survival and is required for inflammation-induced bone loss
- IκB kinase (IKK)-associated protein 1, a common component of the heterogeneous IKK complex
- IκB kinase complex (IKK) triggers detachment-induced autophagy in mammary epithelial cells independently of the PI3K-AKT-MTORC1 pathway
- IκB kinase-2-independent and-dependent inflammation in airway disease models: relevance of IKK-2 inhibition to the clinic
- IκB Kinases (IKK) and Diabetic Retinopathy
- JNK or IKK, AP-1 or NF-κB, which are the targets for MEK kinase 1 action?
- Juncture of the cytoskeleton and innate immune signaling pathways: the role of Suppressor of IKK epsilon (SIKE)
- Kaempferol alleviates insulin resistance via hepatic IKK/NF-κB signal in type 2 diabetic rats
- Kenny mediates selective autophagic degradation of the IKK complex to control innate immune responses
- Kinetic mechanisms of IκB-related kinases (IKK) inducible IKK and TBK-1 differ from IKK-1/IKK-2 heterodimer
- kk IKK the Flatheads. TC Elliott (Oregon Historical Quarterly
- kkkk kkk tO 豎 in the IKK and protection of public health
- KSHV vFLIP binds to IKK-γ to activate IKK
- KSK5104, IKK-β Inhibitor for Treating Reumatoid Arthrotis
- LEVELS OF IL-10 ALTER NF-KAPPA B ACTIVATION THROUGH REGULATION OF I KAPPA KINASE (IKK) IN BOTH HUMAN AND MOUSE CELL TYPES: 273
- LF15‐0195 generates tolerogenic dendritic cells by suppression of NF‐κB signaling through inhibition of IKK activity
- Lin28B mediated IKK-β sustains the stemness of breast cancer stem cell via regulating Wnt/TCF4 and miR-34a/LEF1 signaling pathway
- Linoleic Acid Induces Expression of Monocyte Chemoattractant Protein 1 via PI3K, PKC, IKK, and NF-b Pathway in Retinal Pigment Epihelial Cells
- Lipopolysaccharide induces Rac1-dependent reactive oxygen species formation and coordinates tumor necrosis factor-α secretion through IKK regulation of NF-κB
- Lipopolysaccharide-mediated Interferon Regulatory Factor Activation Involves TBK1-IKK-dependent Lys 63-linked Polyubiquitination and Phosphorylation of …
- Local administration of IKK small molecule inhibitor may enhance fracture healing in osteoporosis patient
- Local and Systemic IKK and NF-B Signaling Associated with Sjögren’s Syndrome Immunopathogenesis
- Local and systemic insulin resistance resulting from hepatic activation of IKK-ßand NF-? B.
- Local and systemic insulin resistance resulting from hepatic activation of IKK-β and NF-κB
- Long-term incubation with proteasome inhibitors (PIs) induces IκBα degradation via the lysosomal pathway in an IκB kinase (IKK)-dependent and IKK-independent …
- Low shear stress preferentially enhances IKK activity through selective sources of ROS for persistent activation of NF-κB in endothelial cells
- LPS induces Rac1-dependent reactive oxygen species (ROS) formation and coordinates TNF-α secretion through IKK regulation of NF-kappa B
- LPS-mediated endothelial activation in pulmonary endothelial cells: role of Nox2-dependent IKK-β phosphorylation
- LRRC14 attenuates Toll-like receptor-mediated NF-κB signaling through disruption of IKK complex
- Lyn kinase controls TLR4-dependent IKK and MAPK activation modulating the activity of TRAF-6/TAK-1 protein complex in mast cells
- Lysine 63-linked polyubiquitination of TAK1 at lysine 158 is required for tumor necrosis factor α-and interleukin-1β-induced IKK/NF-κB and JNK/AP-1 activation
- Maintenance of constitutive NF-κB activity by glycogen synthase kinase-3 and IKK in pancreatic cancer
- Malabaricone C suppresses lipopolysaccharide-induced inflammatory responses via inhibiting ROS-mediated Akt/IKK/NF-κB signaling in murine macrophages
- MALT1 and the API2-MALT1 fusion act between CD40 and IKK and confer NF-κB-dependent proliferative advantage and resistance against FAS-induced cell death in …
- MALT1-ubiquitination triggers non-genomic NF-κB/IKK signaling upon platelet activation
- Marasmius oreades substances block NF-κB activity through interference with IKK activation pathway
- Mature T cells depend on signaling through the IKK complex
- Measurement of IKK activity in primary rat T cells: rapid activation and inactivation
- MECHANIMS OF GENE ACTIVATION BY PATHOGENIC AND INFLAMMATORY STIMULI THROUGH IKK AND NF-KB PATHWAYS: 177
- Mechanism of IKK activation by the Kaposi’s sarcoma-associated herpesvirus protein vFLIP and its cellular homologues
- Mechanism underlying IKK activation mediated by the linear ubiquitin chain assembly complex (LUBAC)
- Mechanisms by which the IKK-related Kinases Affect Energy Expenditure.
- Mechanisms of IKK/NF-κB dependent diabetes development
- Mechanisms of liver injury. I. TNF-α-induced liver injury: role of IKK, JNK, and ROS pathways
- MEKK3 and TAK1 synergize to activate IKK complex in Helicobacter pylori infection
- Melatonin protects from hepatic reperfusion injury through inhibition of IKK and JNK pathways and modification of cell proliferation
- Metformin Improves Insulin Signaling in Obese Rats via Reduced IKK 𝛽 Action in a Fiber-Type Specific Manner
- Metformin inhibits the senescence‐associated secretory phenotype by interfering with IKK/NF‐κ B activation
- Methods for identifying and using IKK inhibitors
- Micrococci and peptidoglycan activate TLR2→ MyD88→ IRAK→ TRAF→ NIK→ IKK→ NF-κB signal transduction pathway that induces transcription of interleukin-8
- Migration and proliferation of human mesenchymai stem cells from patients with systemic lupus erythematosus mediated by IKK-β
- miR-218 inhibits the invasive ability of glioma cells by direct downregulation of IKK-β
- miR-451 inhibits cell proliferation in human hepatocellular carcinoma through direct suppression of IKK-β
- miR‐429 is involved in regulation of NF‐κBactivity by targeting IKK β and suppresses oncogenic activity in cervical cancer cells
- MiR‐503 targets PI3K p85 and IKK‐β and suppresses progression of non‐small cell lung cancer
- Mixed lineage kinase 3 negatively regulates IKK activity and enhances etoposide-induced cell death
- Miyabenol A inhibits LPS-induced NO production via IKK/IκB inactivation in RAW 264.7 macrophages: possible involvement of the p38 and PI3K pathways
- MMP9 reinforces radiation-induced delayed invasion and metastasis of neuroblastoma through second-signaling positive feedback with NFκB via both ERK and IKK …
- Modulation of cellular IKK complexes by human Adenovirus Type 5
- Modulation of gastric mucosal inflammatory responses to Helicobacter pylori by ghrelin: Role of cNOS-dependent IKK-β S-nitrosylation in the regulation of COX-2 …
- Modulation of IKK/NF-B signaling iin pancreatic ß-cells induces diabetes
- Modulation of NF‐κB activation in Theileria annulata‐infected cloned cell lines is associated with detection of parasite‐dependent IKK signalosomes and disruption of …
- Modulation of nuclear factor-kb (NF-kb), IkB kinase (IKK) and inducible nitric oxide synthase (iNOS) via proinflammatory cytokines with adjuvant selenomethionine (Se …
- Modulation of the SMRT co-repressor by IKK: Requirement for NF-κB transcription and cell survival
- Molecular cloning and characterization of an IKK homologue from amphioxus (Branchiostoma belcheri)
- MOLECULAR CLONING, EXPRESSION ANALYSIS AND CHARACTERIZATION OF GRASS CARP IKK-BETA
- Molecular exploration of age-related NF-κB/IKK downregulation by calorie restriction in rat kidney
- Molecular mechanism of inhibitor of κ B kinase (IKK) complex activation by inducible phosphorylation and ubiquitination upon T cell receptor (TCR) …
- Multiple functions of the IKK-related kinase IKKε in interferon-mediated antiviral immunity
- Mutation of an IKK phosphorylation site within the transactivation domain of REL in two patients with B-cell lymphoma enhances REL’s in vitro transforming …
- Mutation of cysteine 46 in IKK-beta increases inflammatory responses
- Myosin motor Myo1c and its receptor NEMO/IKK-γ promote TNF-α–induced serine307 phosphorylation of IRS-1
- Myricetin attenuates lipopolysaccharide‐stimulated activation of mouse bone marrow‐derived dendritic cells through suppression of IKK/NF‐κB and MAPK signalling …
- Myricetin attenuates lipopolysaccharideâ stimulated activation of mouse bone marrowâ derived dendritic cells through suppression of IKK/NFâ κB and MAPK …
- Natural Molecules as IKK α/β Inhibitors useful in the Treatment of Inflammation
- Negative feedback loops: nutrient starvation employs a new tr (IKK) to inhibit PI3K
- NEMO (IKK [gamma]) Mutation Can Be Associated With Opportunistic Infection Without Impairing TLR Function
- NEMO binding domain of IKK‐2 encompasses amino acids 735–745
- NEMO/IKK γ regulates an early NF-κ B-independent cell-death checkpoint during TNF signaling
- Neuroprotective potential of the NF-κB inhibitor peptide IKK-NBD in cerebral ischemia-reperfusion injury
- New functions of NEMO, the regulatory subunit of IKK
- New IKK inhibitors: Synthesis of new imidazo [1, 2-a] quinoxaline derivatives using microwave assistance and biological evaluation as IKK inhibitors
- NF-kappaB targeting by way of IKK inhibition sensitizes lung cancer cells
- NF-kappaB/IKK-2 Signalling Is Not Required For Cigarette Smoke-Induced Airway Inflammation
- NF-κB and IKK as Key Mediators of Inflammation and Oncogenic Progression
- NF-κB and IKK as therapeutic targets in cancer
- NF-κB Induction by Bisperoxovanadium Compounds Requires CD45, p36LAT, PKC, and IKK Activity and Exhibits Kinetics of Activation Comparable to Those of TCR …
- NF-κB Signal Transduction by IKK Complexes
- NF-κB targeting by way of IKK inhibition sensitizes lung cancer cells to adenovirus delivery of TRAIL
- NF-κB-inducing kinase activates IKK-α by phosphorylation of Ser-176
- NF‐κB activation by a signaling complex containing TRAF2, TANK and TBK1, a novel IKK‐related kinase
- NF‐κB activation mechanism of 4‐hydroxyhexenal via NIK/IKK and p38 MAPK pathway
- NF‐κB activation through IKK‐i‐dependent I‐TRAF/TANK phosphorylation
- NFκB inhibition and more: A side-by-side comparison of the inhibitors of IKK and proteasome
- Nitric oxide suppresses LPS-induced inflammation in a mouse asthma model by attenuating the interaction of IKK and Hsp90
- NLRX1 negatively regulates TLR-induced NF-κB signaling by targeting TRAF6 and IKK
- NOffl~-IKK/AND
- Noise-induced oscillatory shuttling of NF-{\kappa} B in a two compartment IKK-NF-{\kappa} BI {\kappa} B-A20 signaling model
- Notch-1 activates estrogen receptor alpha-dependent transcription via IKK alpha
- Notch-1 associates with IKKα and regulates IKK activity in cervical cancer cells
- Novel components of the IKK complex
- Novel cross-talk within the IKK family controls innate immunity
- Novel IKK inhibitors: β-carbolines
- Novel splicing mutation in the NEMO (IKK‐gamma) gene with severe immunodeficiency and heterogeneity of X‐chromosome inactivation
- Novel tight-binding inhibitory factor-κB kinase (IKK-2) inhibitors demonstrate target-specific anti-inflammatory activities in cellular assays and following oral and local …
- Nuclear IKK activity leads to dysregulated notch-dependent gene expression in colorectal cancer
- O019 TLR4-mediated IKK and MAPK activation is regulated by differential post-translational modification of TAK1
- Oncoprotein Bmi-1 renders apoptotic resistance to glioma cells through activation of the IKK-nuclear factor-κB pathway
- Osteopontin induces nuclear factor κB-mediated promatrix metalloproteinase-2 activation through IκBα/IKK signaling pathways, and curcumin (diferulolylmethane) …
- Overcoming adaptive resistance in mucoepidermoid carcinoma through inhibition of the IKK-β/IκBα/NFκB axis
- Overexpression of the tumor suppressor IKK alpha prevents development of malignant carcinomas and metastases in skin
- OXIDANT-INDUCED PRIMING OF THE MACROPHAGE INVOLVES TYROSINE PHOSPHORYLATION OF IKK VIA A SRC KINASE PATHWAY: 164
- Oxidative stress transiently decreases the IKK complex (IKKα, β, and γ), an upstream component of NF-κB signaling, after transient focal cerebral ischemia in mice
- Oyster IKK‐like protein shares structural and functional properties with its mammalian homologues
- P132 The human dead-box helicase 3 couples IKK-epsilon to IRF3 activation
- p27 Kip1 Attenuates Endotoxin-Induced Cardiac Dysfunction Through Inhibition of the IKK-NF-kB Pathway
- p38 MAPK, IKK-2 and Oxidative Stress Regulate Histone 3 Serine 10 Phosphorylation in Blood Monocytes and Alveolar Macrophages.
- p47 negatively regulates IKK activation by inducing the lysosomal degradation of polyubiquitinated NEMO
- P52. The IKK inhibitors celastrol and parthenolide inhibit breast cancer cell proliferation and migration in vitro and osteolytic bone metastasis in vivo
- p53 regulates glucose metabolism through an IKK-NF-κB pathway and inhibits cell transformation
- p62 is required for stem cell/progenitor retention through inhibition of IKK/NF-κB/Ccl4 signaling at the bone marrow macrophage-osteoblast niche
- p85α SH2 domain phosphorylation by IKK promotes feedback inhibition of PI3K and Akt in response to cellular starvation
- PATZ1 induces PP4R2 to form a negative feedback loop on IKK/NF-κB signaling in lung cancer
- Peptides Corresponding to the N and C Termini of IκB-α,-β, and-ε as Probes of the Two Catalytic Subunits of IκB Kinase, IKK-1 and IKK-2
- Periodontitis modulates insulin signaling, c-Jun N-terminal kinase activity, IKK activity, and insulin receptor substrate-1 ser 307 phosphorylation in muscle and …
- Pharmacologic IKK/NF-κB inhibition causes antigen presenting cells to undergo TNFα dependent ROS-mediated programmed cell death
- Pharmacological inhibition and silencing of classical IKK-NF-κB pathway by siRNA sensitizes cancer cells to doxorubicin
- Phosphorylation of H3 serine 10 by IKK α governs cyclical production of ROS in estrogen-induced transcription and ensures DNA wholeness
- Phosphorylation of serine 68 in the IκB kinase (IKK)-binding domain of NEMO interferes with the structure of the IKK complex and tumor necrosis factor-α-induced NF …
- Phosphorylation of TRAF2 within its RING domain inhibits stress-induced cell death by promoting IKK and suppressing JNK activation
- PHYSIOLOGICAL AND PATHOLOGICAL ACTIVATION OF IKK AND IKK-RELATED KINASES
- Piceatannol prevents lipopolysaccharide (LPS)‐induced nitric oxide (NO) production and nuclear factor (NF)‐κB activation by inhibiting IκB kinase (IKK)
- PKA-dependent activation of PKC, p38 MAPK and IKK in macrophage: implication in the induction of inducible nitric oxide synthase and interleukin-6 by dibutyryl …
- PKC-zeta associates and phosphorylates IKK-α/β in breast cancer cells
- PKCβ regulates BCR-mediated IKK activation by facilitating the interaction between TAK1 and CARMA1
- POPX2 phosphatase regulates apoptosis through the TAK1-IKK-NF-κ B pathway
- Potential biomarkers involving IKK/RelA signal in early stage non‐small cell lung cancer
- Pregnancy weight gain limitation by a supervised nutritional program influences placental NF-κB/IKK complex expression and oxidative stress
- Preliminary study of inhibition of human Tenon’s capsule fibroblasts in vitro by RNA interference targeting IKK-beta
- Probing the effect of IKK on FOXO3: a regulatory mechanism of apoptosis and autophagy in chemoresistance
- Profilin–PTEN interaction suppresses NF-κB activation via inhibition of IKK phosphorylation
- Profiling expression of NF-κB signaling target genes in IKK-2 inhibitor treated pterygium and conjunctiva fibroblast cells
- Programming cellular gene expression by IKK mediated NF-κB activation
- Protection from experimental colitis by theaflavin‐3,3′‐digallate correlates with inhibition of IKK and NF‐κB activation
- Protective effect of Aplysin on IKK/NF-kB signaling pathway and related cytokines in rats exposed to ethanol
- Protective effect of Ginkgolids (A+ B) is associated with inhibition of NIK/IKK/IκB/NF-κB signaling pathway in a rat model of permanent focal cerebral ischemia
- Protective effects of organic acid component from Taraxacum mongolicum Hand.-Mazz. against LPS-induced inflammation: regulating the TLR4/IKK/NF-κB signal …
- Protein kinase C-associated kinase regulates NF-κB activation through inducing IKK activation
- Pseudoginsenoside-F11 (PF11) exerts anti-neuroinflammatory effects on LPS-activated microglial cells by inhibiting TLR4-mediated TAK1/IKK/NF-κB, MAPKs and Akt …
- Psoralidin inhibits LPS-induced iNOS expression via repressing Syk-mediated activation of PI3K-IKK-IκB signaling pathways
- PTP1B inhibitor Ertiprotafib is also a potent inhibitor of IκB kinase β (IKK-β)
- QSAR studies on imidazothienopyrazines as IKK‐β inhibitors: from 2D to 3D
- R‐roscovitine sensitizes anaplastic thyroid carcinoma cells to TRAIL‐induced apoptosis via regulation of IKK/NF‐κB pathway
- Rac1 and PAK1 are upstream of IKK‐ε and TBK‐1 in the viral activation of interferon regulatory factor‐3
- RACK1 modulates NF-κB activation by interfering with the interaction between TRAF2 and the IKK complex
- RC3H1 post-transcriptionally regulates A20 mRNA and modulates the activity of the IKK/NF-κB pathway
- Real-time imaging of differential ligand-induced IKK activation and impact on the IκBα: NF-κB negative feedback loop within living cells and mice
- Real-time imaging of ligand-induced IKK activation in intact cells and in living mice
- Recruitment of the IKK signalosome to the p55 TNF receptor: RIP and A20 bind to NEMO (IKKγ) upon receptor stimulation
- Recursion formulae for IKK system with two hierarchies
- Refrigerants-in the focus of attention at the IKK. Kaeltemittel-Messethema Nummer eins
- Regional susceptibility to TNF-α induction of murine brain inflammation via classical IKK/NF-κB signalling
- Regulation and function of IKK and IKK-related kinases
- Regulation of BH3-only proteins by IKK, downstream of beta-common receptor signalling
- Regulation of bone metastasis by the IKK [beta]/FoxO3a axis
- Regulation of cell death and autophagy by IKK and NF‐κB: critical mechanisms in immune function and cancer
- Regulation of expression of Bcl-3 proto-oncogene by IKK ϵ
- Regulation of I-kappa-B kinase (IKK) Pathway by CARMA 1• Bcl-10• MALT-1 (CBM) Complex Promotes SNARE Complex Formation and Secretion in Platelets
- Regulation of IKK
- Regulation of IL-8 expression by IKK and histone deacetylases in ovarian cancer
- Regulation of IκB kinase (IKK) complex by IKKγ-dependent phosphorylation of the T-loop and C terminus of IKKβ
- Regulation of IκB kinase (IKK) γ/NEMO function by IKKβ-mediated phosphorylation
- Regulation of Survival by IKK (epsilon) in Inflammatory Breast Cancer Involves EpCAM
- Regulation of tumor necrosis factor receptor-1 and the IKK-NF-κB pathway by LDL receptor–related protein explains the antiinflammatory activity of this receptor
- Relationship of Inhibitory Effects of Dichroa febrifuga and on the Activation of
- Requirement of Hsp90 activity for I κ B kinase (IKK) biosynthesis and for constitutive and inducible IKK and NF-κ B activation
- Resistin up-regulates COX-2 expression via TAK1-IKK-NF-κB signaling pathway
- Retroviral oncoprotein Tax deregulates NF‐κB by activating Tak1 and mediating the physical association of Tak1–IKK
- RhoA regulation of NF-κB activation is mediated by Cox-2-dependent feedback inhibition of IKK in kidney epithelial cells
- Rituximab-Mediated Inhibition of the Constitutive NIK/IKK/IκB/NF-κB Signaling Pathway in Non-Hodgkin’s Lymphoma (NHL) B-Cell Lines: Role in Chemo-Sensitization …
- Role of cAMP and IKK-2-dependent signaling in the realization of growth potential of mesenchymal progenitor cells
- Role of cAMP-and IKK-2-Dependent Signaling Pathways in Functional Stimulation of Mesenchymal Progenitor Cells with Alkaloid Songorine.
- Role of IKK and ERK pathways in intrinsic inflammation of cystic fibrosis airways
- Role of IKK and oscillatory NFκB kinetics in MMP‐9 gene expression and chemoresistance to 5‐fluorouracil in RKO colorectal cancer cells
- Role of IKK-alpha in the EGFR Signaling Regulation
- Role of IKK/NF-κB signaling in extinction of conditioned place aversion memory in rats
- Role of PI3K/AKT/IKK pathway in NFκB-and β-catenin-dependent transcription in colorectal cancer
- Role of the adaptor protein CIKS in the activation of the IKK complex
- Role of the COP9 Signalosome and IKK Complexes in Atherosclerosis
- Role of the IKK complex during liver regeneration
- Roles of Akt/PKB and IKK complex in constitutive induction of NF-κB in hepatocellular carcinomas of transforming growth factor α/c-myc transgenic mice
- Roles of IKK kinases and protein kinase CK2 in activation of nuclear factor-κB in breast cancer
- Roles of IKK-β, IRF1, and p65 in the activation of chemokine genes by interferon-γ
- Rosiglitazone inhibits hepatic insulin resistance induced by chronic pancreatitis and IKK-β/NF-κB expression in liver
- Rosmarinic acid as a downstream inhibitor of IKK‐β in TNF‐α‐induced upregulation of CCL11 and CCR3
- S 2-38: Activation and homeostatic control of IKK and NF-kB in oncogenesis and innate immunity
- Salicylate Inhibition of IKK [Beta](I [Kappa] B Kinase) Reverses Insulin Resistance in Zucker (fa/fa) Rats
- Saturated FFA Induced NF-κB Activation Is Independent of IKK/IκBα in Aortic Endothelial Cells
- Schisandrin B exerts anti-neuroinflammatory activity by inhibiting the Toll-like receptor 4-dependent MyD88/IKK/NF-κB signaling pathway in lipopolysaccharide …
- Screening of specific SiRNA targeting IKKβ in human keloid fibroblasts and construction of IKK β-siRNA expression vector☆
- Segregation of NF-κ B activation through NEMO/IKK γ by Tax and TNF α: implications for stimulus-specific interruption of oncogenic signaling
- Selective degradation of the IκB kinase (IKK) by autophagy
- Selective Retinoids That Inhibit IKK as Chemotherapeutic Agents Against Estrogen-Independent Breast Cancer Cells
- Selenium Compounds Inhibit IB Kinase (IKK) and Nuclear Factor-B (NF-B) in Prostate Cancer Cells1
- Selenium Compounds Inhibit IκB Kinase (IKK) and Nuclear Factor-κB (NF-κB) in Prostate Cancer Cells 1 Supported by Department of Defense Prostate Cancer …
- Sensitivity analysis of a computational model of the IKK-NF-{\kappa} BI {\kappa} B {\alpha}-A20 signal transduction network
- Sensitivity analysis of parameters controlling oscillatory signalling in the NF-κB pathway: the roles of IKK and IκBα
- Ser484 and Ser494 in REL are the major sites of IKK phosphorylation in vitro: evidence that IKK does not directly enhance GAL4-REL transactivation
- Sesquiterpene lactones inhibit advanced oxidation protein product-induced MCP-1 expression in podocytes via an IKK/NF-κB-dependent mechanism
- Shear stress and VEGF activate IKK via the Flk-1/Cbl/Akt signaling pathway
- Signal Processing by the Control Cycle of the IKK Kinase in the NFκB Signaling Axis
- Signaling by proinflammatory cytokines: oligomerization of TRAF2 and TRAF6 is sufficient for JNK and IKK activation and target gene induction via an amino-terminal …
- Signaling by the Mpl receptor involves IKK and NF‐κB
- Signaling pathways leading to the activation of IKK and MAPK by thymosin α1
- Silencing of the cell cycle checkpoint gene 14‐3‐3σ in basal cell carcinomas correlates with reduced expression of IKK‐α
- Simultaneous inhibition of Rac1 and IKK pathways sensitizes lung cancer cells to TNFα-mediated apoptosis
- Small molecule inhibitors of IKK kinase activity
- Small-molecule inhibitors of IκB kinase (IKK) and IKK-related kinases
- Stable reconstitution of IKK-deficient mouse embryonic fibroblasts
- Statins prevent NF-κB transactivation independently of the IKK-pathway in human endothelial cells
- StIKKing together: do multiple IKK pathways cooperate in the DNA-damage response?
- Stimulation of IKK-γ oligomerization by the human T-cell leukemia virus oncoprotein Tax
- Stimulus specificity of gene expression programs determined by temporal control of IKK activity
- Structure and dynamics of the kinase IKK-β–A key regulator of the NF-kappa B transcription factor
- Structure of a NEMO/IKK-associating domain reveals architecture of the interaction site
- SUBSTITUTED THIOPHENECARBOXAMIDES AS IKK-BETA SERINE-, THREONINE-PROTEIN KINASE INHIBITORS.
- Subthreshold IKK activation modulates the effector functions of primary mast cells and allows specific targeting of transformed mast cells
- Sulforaphane inhibits phorbol ester-stimulated IKK-NF-κB signaling and COX-2 expression in human mammary epithelial cells by targeting NF-κB activating kinase …
- SUMOyla ted CPAP is required for IKK-med iated NF-jB activa tion and enhances HBx-induce d NF-jB signal ing in HCC
- SUMOylated CPAP is required for IKK-mediated NF-κB activation and enhances HBx-induced NF-κB signaling in HCC
- Suppression by IKK-2 Inhibitor of IL-1-Induced Collagen Degradation by Corneal Fibroblasts
- Suppression of cyclooxygenase-2 and inducible nitric oxide synthase expression by epimuqubilin A via IKK/IκB/NF-κB pathways in lipopolysaccharide-stimulated …
- Suppression of NF-κ B and NF-κ B-regulated gene expression by sulforaphane and PEITC through I κ B α, IKK pathway in human prostate cancer PC-3 cells
- Suppression of NF-κB and NF-κB-regulated gene expression by apigenin through IκBα and IKK pathway in TRAMP mice
- Suppression of TNFα‐mediated NFκb activity by myricetin and other flavonoids through downregulating the activity of IKK in ECV304 cells
- Suppressor of IKK epsilon (SIKE) acts as a bridge between innate immune signalling pathway and cytoskeletal rearrangements
- Survivin-2B promotes autophagy by accumulating IKK alpha in the nucleus of selenite-treated NB4 cells
- Sustained activation of protein kinase C downregulates nuclear factor-κB signaling by dissociation of IKK-γ and Hsp90 complex in human colonic epithelial cells
- Sustained, neuron-specific IKK/NF-κB activation generates a selective neuroinflammatory response promoting local neurodegeneration with aging
- Synergistic benefit in inflammatory arthritis by targeting IKK∊ and IFNβ
- Synergy between rhBMP-2 and IKK-inhibitor PS-1145 delivered via a porous biodegradable polymer implant
- Synthesis and biological evaluation of 4-amino derivatives of benzimidazoquinoxaline, benzimidazoquinoline, and benzopyrazoloquinazoline as potent IKK inhibitors
- Synthesis and structure–activity relationship of imidazo (1, 2-a) thieno (3, 2-e) pyrazines as IKK-β inhibitors
- Synthesis and structure–activity relationships of novel IKK-β inhibitors. Part 2: improvement of in vitro activity
- Synthesis and structure–activity relationships of novel IKK-β inhibitors. Part 3: Orally active anti-inflammatory agents
- Synthesis of C‐14 and C‐13, H‐2‐labeled IKK inhibitor: [14C] and [13C4,D3]‐N‐(6‐chloro‐7‐methoxy‐9H‐pyrido[3,4‐b]indol‐8‐yl)‐2‐methyl‐3 …
- Synthesis of C‐14‐labeled novel IKK inhibitor: 2‐[14C]‐N‐(6‐chloro‐9H‐pyrido [3,4‐b]indol‐8‐yl)‐3‐pyridinecarboxamide
- Synthesis of inhibitors of the IKK-complex for the treatment of prostate cancer
- Systematic characterization by mass spectrometric analysis of phosphorylation sites in IRF-3 regulatory domain activated by IKK-i
- T cell receptor signals to NF-κB are transmitted by a cytosolic p62-Bcl10-Malt1-IKK signalosome
- TAK 1 adaptor proteins, TAB 2 and TAB 3, link the signalosome to B‐cell receptor‐induced IKK activation
- TAK-ling IKK activation:“Ub” the judge
- TAK1 is a ubiquitin-dependent kinase of MKK and IKK
- TAK1 Lys-158 but not Lys-209 is required for IL-1β-induced Lys63-linked TAK1 polyubiquitination and IKK/NF-κB activation
- TAK1 lysine 158 is required for TGF-β-induced TRAF6-mediated Smad-independent IKK/NF-κB and JNK/AP-1 activation
- TAK1‐binding protein 2 facilitates ubiquitination of TRAF6 and assembly of TRAF6 with IKK in the IL‐1 signaling pathway
- Tamoxifen reduces infiltration of inflammatory cells, apoptosis and inhibits IKK/NF-kB pathway after spinal cord injury in rats
- Tanshinone IIA inhibits LPS-induced NF-κB activation in RAW 264.7 cells: Possible involvement of the NIK–IKK, ERK1/2, p38 and JNK pathways
- Targeting IKK and NF-κB for therapy
- Targeting IKK in Basal-Like Breast Tumors as a Therapeutic Approach
- Targeting IKK Inhibits Multiple Myeloma (MM) Cell Growth in the Bone Marrow Microenvironment.
- Targeting IKK/NF-κB pathway reduces infiltration of inflammatory cells and apoptosis after spinal cord injury in rats
- Targeting transcription factor NFκB: comparative analysis of proteasome and IKK inhibitors
- Tautomycetin suppresses the TNFα/NF-κB pathway via inhibition of IKK activation
- Tectorigenin regulates adipogenic differentiation and adipocytokines secretion via PPAR γ and IKK/NF-κ B signaling
- Telomere-independent Rap1 is an IKK adaptor and regulates NF-κB-dependent gene expression
- Temporal encoding and homeostatic control in the IKK-kappaNF-kappaB signaling system
- Tendon Healing In Vitro: Activation of NIK, IKK α, IKK β, and NF-κB Genes in Signal Pathway and Proliferation of Tenocytes
- Tetrachlorobenzoquinone exhibits neurotoxicity by inducing inflammatory responses through ROS-mediated IKK/IκB/NF-κB signaling
- Tetrameric oligomerization of IκB kinase γ (IKKγ) is obligatory for IKK complex activity and NF-κB activation
- TfR1 interacts with the IKK complex and is involved in IKK–NF-κB signalling
- TGF-β promotes cancer progression through the xIAP: TAB1: TAK1: IKK axis in mammary epithelial cells
- The adipocyte IKK/NFkappaB pathway: a therapeutic target for insulin resistance.
- The anti-death machinery in IKK/NF-κB signaling
- The anti-inflammatory role for IkappaB kinase (IKK) beta through inhibition of ‘classical’macrophage activation
- The beginning of the end: IκB kinase (IKK) and NF-κB activation
- The carboxyl-terminal region of IκB kinase γ (IKKγ) is required for full IKK activation
- The catalytic subunits of IκB kinase, IKK-1 and IKK-2, contain non-equivalent active sites when expressed as homodimers
- The discovery of 2-amino-3, 5-diarylbenzamide inhibitors of IKK-α and IKK-β kinases
- The distinct roles of TRAF2 and RIP in IKK activation by TNF-R1: TRAF2 recruits IKK to TNF-R1 while RIP mediates IKK activation
- The Drosophila IKK-related kinase (Ik2) and Spindle-F proteins are part of a complex that regulates cytoskeleton organization during oogenesis
- The effect of smoking and smoking cessation on the phosphorylation of IKK-ß in type 2 diabetic rats
- The HSP 90 inhibitor NVP‐AUY 922‐AG inhibits the PI 3K and IKK signalling pathways and synergizes with cytarabine in acute myeloid leukaemia cells
- The IkB kinase complex (IKK) contains two kinase subunits, IKKa and IKKb, necessary for IkB phosphorylation and NF-kB activation
- The IKK complex & TNFR1 signaling to NF-κB
- The IKK complex contributes to the induction of autophagy
- The IKK complex contributes to the induction of autophagy
- The IKK Complex, a Central Regulator of NF-kB Activation
- The IKK complex, a central regulator of NF-κB activation
- The IKK complex: an integrator of all signals that activate NF-κB?
- The IKK inhibitor Bay 11-7082 induces cell death independent from inhibition of activation of NFκB transcription factors
- The IKK inhibitor BMS-345541 affects multiple mitotic cell cycle transitions
- The IKK inhibitor BMS345541 affects aurora kinase expression in human melanoma
- The IKK Inhibitor PS1145 Allows to Overcome Imatinib Resistance.
- The IKK kinases: operators of antiviral signaling
- The IKK NF-κB system: a treasure trove for drug development
- The IKK subunit of I B kinase (IKK) is essential for nuclear factor B activation and prevention of apoptosis
- The IKK-2/IκBα/NF-κB Pathway Plays a Key Role in the Regulation of CCR3 and eotaxin-1 in Fibroblasts A CRITICAL LINK TO DERMATITIS IN IκBα-DEFICIENT MICE
- The IKK-NF-κB pathway: a source for novel molecular drug targets in pain therapy?
- The IKK-related kinases: from innate immunity to oncogenesis
- The IKK‐neutralizing compound Bay11 kills supereffector CD8 T cells by altering caspase‐dependent activation‐induced cell death
- The IKK/NF-κB activation pathway—a target for prevention and treatment of cancer
- The IKK/nf-κb pathway
- The IKK/NF-κB signaling pathway requires Morgana to drive breast cancer metastasis
- The IKK/NFkB & B-catenin pathway is critical for migration, invasion and metastasis in colorectal cancer
- The IKKβ subunit of IκB kinase (IKK) is essential for nuclear factor κB activation and prevention of apoptosis
- The influence of the signal dynamics of activated form of IKK on NF‐κB and anti‐apoptotic gene expressions: A systems biology approach
- The information system on cancer mortality and district characteristics (IKK) of the TUeV Rheinland
- The interplay of IKK, NF‐κB and RIPK 1 signaling in the regulation of cell death, tissue homeostasis and inflammation
- The IκB kinase (IKK) and NF-κB: key elements of proinflammatory signalling
- The IκB Kinase (IKK) and the Control of Immunity, Inflammation and Cancer
- The IκB kinase (IKK) complex as a critical regulator of immune responses
- The IκB kinase (IKK) complex is tripartite and contains IKKγ but not IKAP as a regular component
- The IκB kinase (IKK) inhibitor, NEMO-binding domain peptide, blocks osteoclastogenesis and bone erosion in inflammatory arthritis
- The IκB kinase complex (IKK) contains two kinase subunits, IKKα and IKKβ, necessary for IκB phosphorylation and NF-κB activation
- The IкB Kinase (IKK) Complex
- The microRNA miR-23b suppresses IL-17-associated autoimmune inflammation by targeting TAB2, TAB3 and IKK-α
- The N-terminus of PKR is responsible for the activation of the NF-κB signaling pathway by interacting with the IKK complex
- The NF-κ B pathway blockade by the IKK inhibitor PS1145 can overcome Imatinib resistance
- The NF-κB-independent functions of IKK subunits in immunity and cancer
- The physical association of protein kinase Cθ with a lipid raft-associated inhibitor of κB factor kinase (IKK) complex plays a role in the activation of the NF-κB cascade …
- The primary cilium influences interleukin-1β-induced NFκB signalling by regulating IKK activity
- The prosurvival IKK-related kinase IKKε integrates LPS and IL17A signaling cascades to promote Wnt-dependent tumor development in the intestine
- The role of IKK in constitutive activation of NF-κB transcription factor in prostate carcinoma cells
- The Role of IKK in Interferon–Dependent Signaling
- The role of IKK-induced NF-kB1 p105 proteolysis in T lymphocytes
- The role of the IKK complex in viral infections
- The role of the IKK-2/NF-kB signaling in cigarette smoke-induced airway inflammation
- The role of the IKK/NF-kappa B signaling pathways in the extinction of auditory fear condition
- The role of the non-canonical IKK complex in glioblastoma multiforme
- THE ROLE OF TRAF6 PHOSPHORYLATION IN Src/TRAF6-MEDIATED IKK, JNK, Akt ACTIVATION AND TUMORIGENESIS
- The roles of APC2 and IKK in the regulation of beta-catenin signaling.
- The shrimp IKK–NF-κB signaling pathway regulates antimicrobial peptide expression and may be subverted by white spot syndrome virus to facilitate viral …
- The small-molecule inhibitor selectivity between IKKα and IKKβ kinases in NF-κB signaling pathway
- The TRAF6 ubiquitin ligase and TAK1 kinase mediate IKK activation by BCL10 and MALT1 in T lymphocytes
- The two faces of IKK and NF-κB inhibition: prevention of systemic inflammation but increased local injury following intestinal ischemia-reperfusion
- The UPR inducer DPP23 inhibits the metastatic potential of MDA-MB-231 human breast cancer cells by targeting the Akt–IKK–NF-κB–MMP-9 axis
- The use of IKK inhibitor as a lymphocyte depleting agent (47.4)
- The zinc transporter SLC39A8 is a negative feedback regulator of NF-κB through zinc-mediated inhibition of IKK
- The α and β subunits of IκB kinase (IKK) mediate TRAF2-dependent IKK recruitment to tumor necrosis factor (TNF) receptor 1 in response to TNF
- Theileria-induced constitutive IKK activation is independent of functional Hsp90
- Therapeutic potential of compound K as an IKK inhibitor with implications for osteoarthritis prevention: an in silico and in vitro study
- Therapeutic potential of compound K as an IKK inhibitor with implications for osteoarthritis prevention: an in silico and in vitro study Animal
- THIENOPYRIDAZINES AS IKK INHIBITORS
- Thiophene carboxamides as inhibitors of the enzyme IKK-2
- THU0024 Anti-Inflammatory Inhibitors Targeting Jak and IKK Have An Anabolic Effect on Type II Collagen Turnover ex Vivo
- TIFA activates IκB kinase (IKK) by promoting oligomerization and ubiquitination of TRAF6
- Timosaponin B-II Ameliorates Palmitate-Induced Insulin Resistance and Inflammation via IRS-1/PI3K/Akt and IKK/NF-B Pathways
- TLR7 agonist induced repression of hepatocellular carcinoma via the TLR7-IKK-NF-κB-IL6 signaling pathway
- TNF and IL-1 exhibit distinct ubiquitin requirements for inducing NEMO–IKK supramolecular structures
- TNF-induced recruitment and activation of the IKK complex require Cdc37 and Hsp90
- TNF-α modulation of intestinal tight junction permeability is mediated by NIK/IKK-α axis activation of the canonical NF-κB pathway
- TNF-α-induced loss of IKK-α in skeletal muscle: implications for skeletal muscle oxidative phenotype
- TNFR1 determines progression of chronic liver injury in the IKK γ/Nemo genetic model
- TNFR1 signaling kinetics: spatiotemporal control of three phases of IKK activation by posttranslational modification
- TNFα induces chromosomal abnormalities independent of ROS through IKK, JNK, p38 and caspase pathways
- Tracking the road from inflammation to cancer: the critical role of IkappaB kinase (IKK)
- TRAF2 exerts opposing effects on basal and TNFα-induced activation of the classic IKK complex in hematopoietic cells in mice
- TRAF2 plays a critical role in maintaining lymphocyte homeostasis by regulating the basal activities of IKK and caspase-8
- TRAF2 suppresses basal IKK activity in resting cells and TNFα can activate IKK in TRAF2 and TRAF5 double knockout cells
- TRAF5-mediated Tax ubiquitination modulates IKK phosphorylation but not binding to NEMO
- Transient activation of NF-κ B through a TAK1/IKK kinase pathway by TGF-β 1 inhibits AP-1/SMAD signaling and apoptosis: implications in liver tumor …
- Triggering the interferon antiviral response through an IKK-related pathway
- Triggering the Interferon Antiviral Response Through an IKK-Related Pathway
- TRIM22 can activate the noncanonical NF-κ B pathway by affecting IKK α
- Tumor necrosis factor α stimulates endothelin-1 synthesis in rat hepatic stellate cells in hepatic wound healing through a novel IKK/JNK pathway
- Tumor necrosis factor α triggers proliferation of adult neural stem cells via IKK/NF-κB signaling
- Tumor necrosis factor α-dependent drug resistance to purine and pyrimidine analogues in human colon tumor cells mediated through IKK
- Tumor necrosis factor-α-induced IKK phosphorylation of NF-κB p65 on serine 536 is mediated through the TRAF2, TRAF5, and TAK1 signaling pathway
- Tunable signal processing through a kinase control cycle: the IKK signaling node
- Two coordinated mechanisms underlie TNFα-induced immediate and delayed IKK activation
- Two roles for the Drosophila IKK complex in the activation of Relish and the induction of antimicrobial peptide genes
- Ubiquitin-mediated activation of TAK1 and IKK
- Ubiquitin, TAK1 and IKK: is there a connection?
- Ubiquitination in signaling to and activation of IKK
- Ubiquitination-Dependent Activation of IKK
- Ubiquitylated Tax targets and binds the IKK signalosome at the centrosome
- Uncoupling the mechanisms of obesity and hypertension by targeting hypothalamic IKK-β and NF-κB
- Upregulation of IKK α/IKK β by integrin-linked kinase is required for HER2/neu-induced NF-κ B antiapoptotic pathway
- Use of molecular imaging to quantify response to IKK‐2 inhibitor treatment in murine arthritis
- Using RNA interference in lung cancer cells to target the IKK-NF-κB pathway
- Using structural analysis to investigate the function of Suppressor of IKK-epsilon (SIKE)
- Vaccinia virus E3L protein inhibits type I IFN induction throughthe RLH pathway and associates with MDA-5 and IKK-ϵ
- Validation of the anti-inflammatory properties of small-molecule IκB kinase (IKK)-2 inhibitors by comparison with adenoviral-mediated delivery of dominant-negative …
- Vinpocetine inhibits NF-κB–dependent inflammation via an IKK-dependent but PDE-independent mechanism
- Water extract of Cynanchi atrati Radix regulates inflammation and apoptotic cell death through suppression of IKK-mediated NF-κB signaling
- Wedelolactone suppresses LPS-induced caspase-11 expression by directly inhibiting the IKK complex
- WNT5A regulates chondrocyte differentiation through differential use of the CaN/NFAT and IKK/NF-κB pathways
- α-Catulin, a Rho signalling component, can regulate NF-κB through binding to IKK-β, and confers resistance to apoptosis
- β-Adrenergic stimulation induces interleukin-18 expression via β2-AR, PI3K, Akt, IKK, and NF-κB
- β-Carboline alkaloid suppresses NF-κB transcriptional activity through inhibition of IKK signaling pathway
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