PREMATURE SENESCENCE
January 7, 2020ONCOGENE ACTIVATION
January 8, 2020A hallmark of aging is chronic, low-grade, “sterile” inflammation (1–3). Elevated proinflammatory cytokines and chemokines are closely associated with mortality (4, 5) and with a variety of age-related diseases, including atherosclerosis (6), depression (7), cancers (8), diabetes (9), and neurodegenerative diseases (10, 11). Inflammation also is associated with frailty, a geriatric syndrome characterized by decreased strength and incapacity to respond to stress (2).
The underlying mechanisms of age-related chronic inflammation, tissue dysfunction, and frailty remain elusive. Cellular senescence, stable arrest of cell growth in replication-competent cells, is a plausible contributor. Senescence can be induced by a number of stimuli and stresses, including telomere dysfunction, genomic instability, oncogenic and metabolic insults, and epigenetic changes (12). Senescent cells accumulate with aging in the skin (13, 14), liver (15, 16), kidney (17), the cardiovascular system (18), and other tissues in various species (16). The senescence-associated secretory phenotype (SASP), largely comprised of proinflammatory cytokines and chemokines (19, 20), links senescent cells to age-related inflammation and diseases. We found that elimination of senescent cells delayed the onset of age-related phenotypes and enhanced healthspan (21, 22). Therefore, senescent cells and the SASP could play a role in age-related pathologies, particularly those that involve systemic inflammation.
The JAK/STAT pathway plays an important role in regulating cytokine production (23, 24). We hypothesized that it may directly affect the SASP. The JAK family has four members: JAK1, JAK2, JAK3, and tyrosine kinase 2 (TYK2). JAK1 and 2 are involved in inflammatory signaling and in the action of growth hormone and other endocrine and paracrine signals (25). JAK3 is expressed primarily in blood cells and mediates erythropoietin signaling and immune cell generation (26–29). TYK2 plays an important role in white blood cell function and host defenses (30, 31). A number of inhibitors that target different JAKs have been approved or are in phase I–III studies for treating myelofibrosis (23, 32–34), acute myeloid leukemia (23), lymphoma (23), and rheumatoid arthritis (23, 35, 36). JAK inhibitors recently have been found to reprogram the SASP in senescent tumor cells, contributing to improved antitumor response (37). Therefore, we investigated the role of the JAK pathway in age-related inflammation and dysfunction.
We demonstrate here that senescent preadipocytes, fat cell progenitors, accumulate in adipose tissue with aging and can contribute to adipose tissue inflammation. We found that JAK inhibitors decrease the SASP in preadipocytes and human umbilical vein endothelial cells (HUVECs). They also decrease age-related adipose tissue and systemic inflammation as well as frailty. Our findings provide insights into the possible contribution of senescent cells to age-related inflammation and, in turn, to age-related pathologies, as well as potential therapeutic targets to alleviate age-related dysfunction.
- The effect of JAK inhibition on neutrophil killing, netosis and metabolism in rheumatoid arthritis
- JAK Inhibition by Tofacitinib Improves Rheumatoid Cachexia in a Rabbit Experimental Model That Reproduces the Lipid Paradox in Humans
- JAK-inhibition with peficitinib and filgotinib in fibroblast-like synoviocytes in rheumatoid arthritis
- Combined MEK and JAK inhibition rescues mutant hematopoietic stem cell function and provides long-term survival in NrasG12D/G12D mice
- gp130/Jak/Stat3 inhibition blocks WNT signaling-mediated intestinal tumorigenesis and regeneration
- Effects of JAK pathway inhibition in pre-clinical models of breast cancer bone marrow metastases
- Repurposing Jak/Stat Signaling Inhibition to Enhance Costimulation Blockade and Promote Transplant Acceptance
- Resistance to tyrosine kinase inhibitors reversed by selective JAK inhibition
- Activating JAK1 mutation may predict the sensitivity of JAK-STAT inhibition in hepatocellular carcinoma
- Alopecia areata is driven by cytotoxic T lymphocytes and is reversed by JAK inhibition
- Alternatively spliced, truncated GCSF receptor promotes leukemogenic properties and sensitivity to JAK inhibition
- Anti-myeloma effects of ruxolitinib combined with bortezomib and lenalidomide: A rationale for Jak/Stat pathway inhibition in myeloma patients
- Arsenic inhibition of the JAK-STAT pathway
- Assessing efficacy in myelofibrosis treatment: a focus on JAK inhibition
- Baricitinib: JAK inhibition for rheumatoid arthritis.
- Benefits and risks of JAK inhibition
- BET’ing on Dual JAK/BET Inhibition as a Therapeutic Strategy for Myeloproliferative Neoplasms
- Blockade of PDGFRβ circumvents resistance to MEK-JAK inhibition via intratumoral CD8+ T-cells infiltration in triple-negative breast cancer
- C34 NEW BASIC SCIENCE IN ASTHMA: Effect Of Janus Kinase (jak) Inhibition On Thymic Stromal Lymphopoietin (tslp) Response In Monocyte Derived Dendritic …
- Combined MEK and JAK inhibition abrogates murine myeloproliferative neoplasm
- Compositions and methods for inhibition of the JAK pathway
- Danzhi Jiangtang Capsule ameliorates kidney injury via inhibition of the JAK-STAT signaling pathway and increased antioxidant capacity in STZ-induced diabetic …
- Decreased NK-cell tumour immunosurveillance consequent to JAK inhibition enhances metastasis in breast cancer models
- Discovery of a JAK3-selective inhibitor: functional differentiation of JAK3-selective inhibition over pan-JAK or JAK1-selective inhibition
- Dual SYK/JAK inhibition overcomes ibrutinib resistance in chronic lymphocytic leukemia: cerdulatinib, but not ibrutinib, induces apoptosis of tumor cells …
- Effect Of Janus Kinase (jak) Inhibition On Thymic Stromal Lymphopoietin (tslp) Response In Monocyte Derived Dendritic Cells (mddcs)
- Efficacy of JAK 1/2 inhibition in the treatment of diffuse non-scarring alopecia due to systemic lupus erythematosus
- Efficacy of selective JAK inhibition in models of leukemia, lymphoma, myeloma, and JAK2V617F dependent malignancy
- Evaluation of JAK inhibition with topical tofacitinib in an experimental autoimmune uveitis model (EAU)
- Ex vivo inhibition of JAK and IKK preserves cartilage formation in catabolically stimulated bovine articular cartilage
- How we manage JAK inhibition in allogeneic transplantation for myelofibrosis
- Hsp90 inhibition disrupts JAK-STAT signaling and leads to reductions in splenomegaly in patients with myeloproliferative neoplasms
- Immunological consequences of JAK inhibition: friend or foe?
- Improved efficacy of allergen-specific immunotherapy by JAK inhibition in a murine model of allergic asthma
- Improved JAK inhibition in myelofibrosis—the long road ahead
- Improvement of spontaneous locomotor activity with JAK inhibition by JTE-052 in rat adjuvant-induced arthritis
- In vitro JAK kinase activity and inhibition assays
- Inhibition of IL-6/Jak/Stat3 signaling: a novel and potent targeting therapy for lung cancer
- Inhibition of JAK kinases in patients with rheumatoid arthritis: scientific rationale and clinical outcomes
- Inhibition of Jak/Stat pathway restrains TSLP-activated dendritic cells mediated inflammatory T helper type 2 cell response in allergic rhinitis
- Inhibition of Jak/Stat signaling in rheumatologic disorders: The expanding spectrum
- Inhibition of Jak/Stat signaling reduces the activation of pancreatic stellate cells in vitro and limits caerulein-induced chronic pancreatitis in vivo
- Inhibition of Jak/Stat Signaling Synergizes with CTLA4-Ig to Promote Transplant Survival
- JAK inhibition in STING-associated interferonopathy
- Inhibition of Janus kinase/signal transducer and activator of transcription (Jak/Stat) signalling pathway in rheumatoid synovial fibroblasts using small molecule …
- Inhibition of related Jak/Stat pathways with molecular targeted drugs shows strong synergy with ruxolitinib in chronic myeloproliferative neoplasm
- Inhibition of TAK1 and/or JAK can rescue impaired chondrogenic differentiation of human mesenchymal stem cells in osteoarthritis-like conditions
- Inhibition of the Jak/Stat pathway protects against α-synuclein-induced neuroinflammation and dopaminergic neurodegeneration
- JAK inhibition alleviates the cellular senescence-associated secretory phenotype and frailty in old age
- JAK inhibition and modulation of T cell function
- JAK inhibition and progressive kidney disease
- JAK inhibition as a therapeutic strategy for immune and inflammatory diseases
- JAK inhibition blocks rna interference associated toxicities
- JAK inhibition by methotrexate (and csDMARDs) may explain clinical efficacy as monotherapy and combination therapy
- JAK inhibition for the treatment of rheumatoid arthritis: a new era in oral DMARD therapy
- JAK inhibition impairs NK cell function in myeloproliferative neoplasms
- JAK inhibition in inflammatory bowel disease
- JAK-inhibition-myelofibrosis/22/00006024″>JAK inhibition in myelofibrosis
- JAK inhibition in rheumatoid arthritis
- JAK inhibition in the myeloproliferative neoplasms: lessons learned from the bench and bedside
- JAK inhibition in the treatment of alopecia areata–a promising new dawn?
- JAK inhibition in the treatment of diabetic kidney disease
- JAK Inhibition Induces Browning of White Adipocytes
- JAK inhibition induces silencing of T Helper cytokine secretion and a profound reduction in T regulatory cells
- JAK inhibition reverses IL10-mediated resistance to B cell receptor (BCR) pathway inhibition in DLBCL
- JAK inhibition using tofacitinib for inflammatory bowel disease treatment: a hub for multiple inflammatory cytokines
- JAK inhibition with ruxolitinib as pretreatment for allogeneic stem cell transplantation in primary or post-ET/PV myelofibrosis
- JAK inhibition with ruxolitinib versus best available therapy for myelofibrosis
- JAK inhibition with tofacitinib curbs RANKL-induced joint damage
- JAK inhibition with tofacitinib suppresses arthritic joint structural damage through decreased RANKL production
- JAK inhibition, but not Stat1 knockdown, blocks the synergistic effect of IFN-γ on Fas-induced apoptosis of A549 human non-small cell lung cancer cells
- JAK-inhibition-a-new-therapeutic-strategy-for-management-of-chronic-diseases-2167-7956-1000e148.pdf”>JAK Inhibition: A new therapeutic strategy for management of chronic diseases
- JAK inhibition: the key to treating myeloproliferative neoplasm?
- JAK Inhibition: The Most Promising Agents in the IBD Pipeline?
- JAK kinase inhibition abrogates STAT3 activation and head and neck squamous cell carcinoma tumor growth
- JAK Stat signaling and cancer: Opportunities, benefits and side effects of targeted inhibition
- Jak/Stat inhibition in macrophages promotes therapeutic resistance by inducing expression of protumorigenic factors
- Jak/Stat pathway inhibition overcomes IL7-induced glucocorticoid resistance in a subset of human T-cell acute lymphoblastic leukemias
- JAK‐1 Inhibition Suppresses Interferon‐Induced BAFF Production in Human Salivary Gland: Potential Therapeutic Strategy for Primary Sjögren’s Syndrome
- JAK-2 Inhibition: Current Roles in Myelofibrosis and Initial Lessons Learned from Mexico
- JAK-INHIBITION WITH RUXOLITINIB IN PATIENTS WITH RELAPSED OR REFRACTORY CLASSICAL HODGKIN LYMPHOMA: A PHASE II, OPEN LABEL …
- JAK‐STAT inhibition impairs K‐RAS‐driven lung adenocarcinoma progression
- Management of myelofibrosis: JAK inhibition and beyond
- NK cell modulation by JAK inhibition
- OP0155 Development of A JAK3 Specific Inhibitor Clinical Candidate: Functional Differentiation of JAK3 Selective Inhibition over PAN-JAK or JAK1 Selective Inhibition
- Overcoming acquired resistance to HSP90 inhibition by targeting JAK-STAT signalling in triple-negative breast cancer
- P148 JAK-inhibition by baricitinib and tofacitinib ameliorates pathological bone loss
- Partial inhibition of gp130-JAK-Stat3 signaling prevents Wnt–β-catenin–mediated intestinal tumor growth and regeneration
- Pathogenic and therapeutic relevance of Jak/Stat signaling in systemic lupus erythematosus: integration of distinct inflammatory pathways and the prospect of their …
- Pharmacologic inhibition of JAK-STAT signaling promotes hair growth
- RAF associates with phosphorylated nuclear BubR1 during endoreduplication induced by JAK inhibition
- Response to:’JAK inhibition in STING-associated interferonopathy’by Crow et al
- Selective functional inhibition of JAK‐3 is sufficient for efficacy in collagen‐induced arthritis in mice
- Selective JAK inhibition for AS
- Selective JAK inhibition proves efficacious in epithelial cancer models
- Selective Jak/Stat Inhibition: Signaling a Way Forward in the Management of Myelofibrosis.
- Signal inhibition reveals Jak/Stat3 pathway as critical for bovine inner cell mass development
- Simultaneous inhibition of JAK and SYK kinases ameliorates chronic and destructive arthritis in mice
- SOCS3 binds specific receptor–JAK complexes to control cytokine signaling by direct kinase inhibition
- SP0169 JAK inhibition in patients with rheumatoid arthritis
- Specificity of JAK-kinase inhibition determines impact on human and murine T-cell function
- Sustained src inhibition results in STAT3 activation and cancer cell survival via altered JAK-STAT3 binding
- The colony-stimulating factor 3 receptor T640N mutation is oncogenic, sensitive to JAK inhibition, and mimics T618I
- The future of JAK inhibition in myelofibrosis and beyond
- The JAK inhibitor ruxolitinib impairs dendritic cell migration via off-target inhibition of ROCK
- The JAK inhibitor tofacitinib regulates synovitis through inhibition of interferon‐γ and interleukin‐17 production by human CD4+ T cells
- The molecular basis of Jak/Stat inhibition by SOCS1
- Therapeutic inhibition of JAK activity inhibits progression of gastrointestinal tumors in mice
- THU0040 Enhancement of early human b cell development by JAK inhibition
- THU0044 Simultaneous Inhibition of JAK and Syk Kinases Ameliorates Chronic, Severe and Destructive Arthritis in Mice
- Type I interferon signature predicts response to JAK inhibition in haploinsufficiency of A20
- Varicella Zoster Infection Associated with Pharmacological JAK-STAT Inhibition via Ruxolitinib in Myeloproliferative Diseases
- White-to-brown metabolic conversion of human adipocytes by JAK inhibition
- 064 Early experience with JAK inhibitor prescribing in the UK: results from the British Society for Rheumatology Biologics Register for Rheumatoid Arthritis (BSRBR …
- 233: The Prevention of Acute Rejection with a Novel JAK Inhibitor
- 3-Amido pyrrolopyrazine JAK kinase inhibitors: development of a JAK3 vs JAK1 selective inhibitor and evaluation in cellular and in vivo models
- 3-O-methylthespesilactam, a new small-molecule anticancer pan-JAK inhibitor against A2058 human melanoma cells
- A Macromolecular Janus Kinase (JAK) Inhibitor Prodrug Effectively Ameliorates Dextran Sulfate Sodium-Induced Ulcerative Colitis in Mice
- A new player in psoriatic arthritis: a JAK inhibitor
- A novel JAK inhibitor JTE‐052 reduces skin inflammation and ameliorates chronic dermatitis in rodent models: Comparison with conventional therapeutic agents
- A novel JAK inhibitor, peficitinib, demonstrates potent efficacy in a rat adjuvant-induced arthritis model
- A novel JAK-STAT inhibitor, 2-[(3-Carbamoyl-2-thienyl) amino]-2-oxoethyl (2, 6-dichlorophenyl) acetate, suppresses helper T cell differentiation in vitro and collagen …
- A Phase 2 Study of the Dual SYK/JAK Inhibitor Cerdulatinib Demonstrates Good Tolerability and Clinical Response in Relapsed/Refractory Peripheral T-Cell …
- A phase I/II study of INCB018424, an oral, selective JAK inhibitor, in patients with primary myelofibrosis (PMF) and post polycythemia vera/essential thrombocythemia …
- A phase I/II study of the Janus kinase (JAK) 1 and 2 inhibitor ruxolitinib in patients with relapsed or refractory acute myeloid leukemia
- A phase IIb dose‐ranging study of the oral JAK inhibitor tofacitinib (CP‐690,550) versus placebo in combination with background methotrexate in patients with active …
- A phase IIb study of ABT‐494, a selective JAK‐1 inhibitor, in patients with rheumatoid arthritis and an inadequate response to anti–tumor necrosis factor therapy
- A Practical and Scalable Method for Manufacturing JAK Inhibitor ASP3627
- A randomized phase 2b trial of baricitinib, an oral Janus kinase (JAK) 1/JAK2 inhibitor, in patients with moderate‐to‐severe psoriasis
- A retrospective cohort study comparing utilization and costs of biologic therapies and JAK inhibitor therapy across four common inflammatory indications in …
- A32 NEW ASTHMA THERAPIES: CLINICAL STUDIES: In Vitro Profile Of The New Pan-JAK Inhibitor Compound A
- AB0066 THE JAK INHIBITOR (BARICITINIB) INHIBITS IFNΓ-INDUCED GLIOSTATIN EXPRESSION IN HUMAN FIBROBLAST-LIKE SYNOVIOCYTES
- AB0076 JAK inhibitor baricitinib modulates human innate and adaptive immune system
- AB0434 EARLY EXPERIENCE WITH JAK INHIBITOR PRESCRIBING IN THE UK: RESULTS FROM THE BRITISH SOCIETY FOR RHEUMATOLOGY BIOLOGICS …
- Aberrant cytokine production by nonmalignant cells in the pathogenesis of myeloproliferative tumors and response to JAK inhibitor therapies
- Abstract CT144: preclinical and clinical studies and modeling and simulation to identify phase II dose for cerdulatinib: a dual SYK/JAK inhibitor for the treatment of B …
- Abstract P2-08-03: Targeting inflammatory pathways: A phase 2 trial of the JAK-inhibitor ruxolitinib in combination with exemestane for aromatase inhibitor-resistant …
- Accumulation of JAK activation loop phosphorylation is linked to type I JAK inhibitor withdrawal syndrome in myelofibrosis
- ACTIVITY OF THE NOVEL AND SELECTIVE PANJANUS KINASE (JAK) INHIBITOR VR588 IN A MURINE POLYINOSINIC: POLYCYTIDILIC ACID (POLY (I: C)) …
- Allo-SCT for myelofibrosis: reversing the chronic phase in the JAK inhibitor era?
- Anti-adult T‑cell leukemia/lymphoma activity of cerdulatinib, a dual SYK/JAK kinase inhibitor
- Antiangiogenic and antimetastatic activity of JAK inhibitor AZD1480
- Anti-inflammatory effects of the JAK inhibitor tofacitinib in two murine house dust mite-driven models of asthma.
- AS2553627, a novel JAK inhibitor, prevents chronic rejection in rat cardiac allografts
- ASN002: A novel dual SYK/JAK inhibitor with strong antitumor activity
- ASN002: A novel dual SYK/JAK inhibitor with strong antitumor activity in both hematological and solid tumor xenograft models
- Atypical chronic myeloid leukemia with concomitant CSF3R T618I and SETBP1 mutations unresponsive to the JAK inhibitor ruxolitinib
- AZD1480, a JAK inhibitor, inhibits cell growth and survival of colorectal cancer via modulating the JAK2/STAT3 signaling pathway
- Baricitinib: The Second FDA-Approved JAK Inhibitor for the Treatment of Rheumatoid Arthritis
- Beyond JAK inhibitor therapy in myelofibrosis
- Biology and clinical management of myeloproliferative neoplasms and development of the JAK inhibitor ruxolitinib
- C32 ASTHMA: PRE-CLINICAL STUDIES: New Inhaled Pan-JAK Inhibitor A Is Efficacious At Reducing Allergen-Induced Airway Inflammation In Rat
- C34 NEW BASIC SCIENCE IN ASTHMA: ALLERGIC INFLAMMATION I: The Selective Pan-Janus Kinase (jak) Inhibitor Vr588 Demonstrates Potent Anti-Inflammatory …
- Calcineurin‐Inhibitor‐Free Immunosuppression Based on the JAK Inhibitor CP‐690,550: A Pilot Study in De Novo Kidney Allograft Recipients
- Calreticulin mutant mice develop essential thrombocythemia that is ameliorated by the JAK inhibitor ruxolitinib
- Case report: successful treatment of refractory SAPHO syndrome with the JAK inhibitor tofacitinib
- CD45 antigen negativity in T-lineage ALL correlates with PTPRC mutation and sensitivity to a selective JAK inhibitor.
- Cerdulatinib (PRT062070): A dual SYK/JAK inhibitor in patients with relapsed/refractory b-cell malignancies—Pharmacokinetic and pharmacodynamic outcomes with …
- Challenges facing JAK inhibitor therapy for myeloproliferative neoplasms
- CHZ868, a type II JAK2 inhibitor, reverses type I JAK inhibitor persistence and demonstrates efficacy in myeloproliferative neoplasms
- Clinical activity, safety and tolerability of ASN002, a dual SYK/JAK inhibitor, in patients non-Hodgkin lymphoma (NHL) and solid tumors.
- Clinical utility of the oral JAK inhibitor tofacitinib in the treatment of rheumatoid arthritis
- Co‐administration of the JAK inhibitor CP‐690,550 and methotrexate is well tolerated in patients with rheumatoid arthritis without need for dose adjustment
- Combination synergy of JAK inhibitor, BVB808, and FGFR inhibitor, BGJ398, in an FGFR3-driven multiple myeloma model
- Combination Therapy of Selective MMP9 Inhibitor and JAK Inhibitor Is Effective to Induce Disease Control in Mouse DSS Model of Colitis: 593
- Combined Therapy With BRD4 Antagonist and JAK Inhibitor Is Synergistically Lethal Against Human Myeloproliferative Neoplasm (MPN) Cells
- Combined use of tofacitinib (pan-JAK inhibitor) and ruxolitinib (a JAK1/2 inhibitor) for refractory T-cell prolymphocytic leukemia (T-PLL) with a JAK3 mutation
- Cytokine-mediated signals as targets for treatment of rheumatoid arthritis: a JAK inhibitor in vitro and in vivo
- Development of a Scalable Synthesis for an Inhaled pan-JAK Inhibitor
- Discovery and structural characterization of peficitinib (ASP015K) as a novel and potent JAK inhibitor
- Discovery of CP-690,550: a potent and selective Janus kinase (JAK) inhibitor for the treatment of autoimmune diseases and organ transplant rejection
- Disease course and treatment effects of a JAK inhibitor in a patient with CANDLE syndrome
- Distinct acute lymphoblastic leukemia (ALL)-associated Janus kinase 3 (JAK3) mutants exhibit different cytokine-receptor requirements and JAK inhibitor specificities
- DOP076 A phase 2B, multicenter, randomized, placebo-controlled dose-ranging trial of peficitinab, an oral JAK inhibitor, in patients with moderately to severely active …
- DOP53 Clinical, endoscopic, histological and biomarker activity following treatment with the gut-selective, pan-JAK inhibitor TD-1473 in moderately to severely active …
- DRESS syndrome and reversible liver function abnormalities in patients with systemic lupus erythematosus treated with the highly selective JAK-1 inhibitor …
- Effect of filgotinib, a selective JAK 1 inhibitor, with and without methotrexate in patients with rheumatoid arthritis: patient-reported outcomes
- Effective JAK inhibitor therapy in rheumatoid arthritis: can methotrexate be discontinued?
- Effective prevention and treatment of CD8 T cell-mediated graft-versus-host-like disease (GvHD) using a JAK inhibitor.(51.3)
- Effects of a JAK inhibitor, AG490, on proliferation and apoptosis of human nasopharyngeal carcinoma cell line CNE-2Z
- Effects of a JAK inhibitor, AG490, on proliferation and survivin expression of breast cancer cell line MDA-MB-231
- Effects Of PF-956980, A Pan JAK Inhibitor, On Glucocorticosteroid Resistant Release Of CXCR3 Chemokines From Human bronchial Epithelial Cells
- Effects of the novel aurora kinase/JAK inhibitor, AT9283 and imatinib on Philadelphia positive cells in vitro
- Efficacy and safety of ABT‐494, a selective JAK‐1 inhibitor, in a phase IIb study in patients with rheumatoid arthritis and an inadequate response to …
- Efficacy and safety of JAK inhibitor INC424 in patients with primary and post-polycythemia vera or post-essential thrombocythemia myelofibrosis in the Chinese …
- Efficacy and safety of JAK inhibitor ruxolitinib in Chinese patients with myelofibrosis: results of a 1-year follow-up of A2202
- Efficacy and safety of the dual SYK/JAK inhibitor cerdulatinib in patients with relapsed or refractory B-cell malignancies: Results of a phase I study.
- Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of Filgotinib, a Selective JAK‐1 Inhibitor, After Short‐Term Treatment of Rheumatoid Arthritis: Results of …
- Elevation of the hepatitis B virus DNA during the treatment of polycythemia vera with the JAK kinase inhibitor ruxolitinib
- Enhanced antitumor activity of cetuximab in combination with the JAK inhibitor cyt387 against non-small-cell lung cancer with various genotypes
- Evaluation of the in vitro and in vivo efficacy of the JAK inhibitor AZD1480 against JAK-mutated acute lymphoblastic leukemia
- Flavopiridol disrupts STAT3/DNA interactions, attenuates STAT3-directed transcription, and combines with the JAK kinase inhibitor AG490 to achieve cytotoxic synergy
- FLLL12 is a small molecule JAK2 inhibitor that inhibits JAK-STAT3 pathway in head and neck cancer
- FRI0041 The JAK Inhibitor (Tofacitinib) Inhibits TNF-Induced Gliostatin/thymidine Phosphorylase Expression in Human Fibroblast-like Synoviocytes
- Gö6976 is a potent inhibitor of the JAK 2 and FLT3 tyrosine kinases with significant activity in primary acute myeloid leukaemia cells
- Heterodimeric JAK–STAT activation as a mechanism of persistence to JAK2 inhibitor therapy
- Immunotherapy: JAK inhibitor effective in rheumatoid arthritis
- Impact of treatment of a JAK inhibitor on experimental Candida sepsis: Keeping the balance of inflammation prolongs survival
- In vitro and in vivo analysis of a JAK inhibitor in rheumatoid arthritis
- In vitro pharmacological characterization of the potent, lung selective pan-JAK inhibitor TD-8236
- In vitro profile of the new inhaled pan-JAK inhibitor LAS194046
- In vitro/in vivo investigations to examine the gender differences in the pharmacokinetics of novel oral Janus kinase (JAK) inhibitor ASP015K and sulfate metabolite M2 …
- Increasing Antitumor Activity of JAK Inhibitor by Simultaneous Blocking Multiple Survival Signaling Pathways in Human Ovarian Cancer
- Incyte comes of age with JAK inhibitor approval
- Influence of JAK kinase inhibitor AG490 on Lewis lung cancer cell proliferation and JAK-Stat signaling pathways
- Inhibition of cytokine‐induced JAK‐STAT signalling pathways by an endonuclease inhibitor aurintricarboxylic acid
- Inhibition of STAT3 with orally active JAK inhibitor, AZD1480, decreases tumor growth in Neuroblastoma and Pediatric Sarcomas In vitro and In vivo
- Inhibitory effect of JAK inhibitor on mechanical stress-induced protease expression by human articular chondrocytes
- Inhibitory effect of the JAK inhibitor AG490 on the STAT3 signaling pathway in laryngeal carcinoma
- Inhibitory effects of JAK inhibitor AG490 on invasion and migration in MCF-7 cells [J]
- Inhibitory effects of the JAK inhibitor CP690, 550 on human CD4+ T lymphocyte cytokine production
- In-vitro evaluation of a new potent, selective pan-Janus kinase (JAK) inhibitor VR588
- JAK inhibitor
- JAK inhibitor has the amelioration effect in lupus-prone mice: the involvement of IFN signature gene downregulation
- JAK inhibitor improves type I interferon induced damage: proof of concept in dermatomyositis
- JAK inhibitor in CALR-mutant myelofibrosis.
- JAK inhibitor induces S phase cell-cycle arrest and augments TRAIL-induced apoptosis in human hepatocellular carcinoma cells
- JAK inhibitor JTE-052 regulates contact hypersensitivity by downmodulating T cell activation and differentiation
- JAK inhibitor ruxolitinib inhibits the expression of cytokines characteristic of cutaneous lupus erythematosus
- JAK inhibitor shows potential for CNI-free immunosuppression, but regimen needs refining
- JAK inhibitor therapy for myelofibrosis: critical assessment of value and limitations
- JAK Inhibitor Therapy: Safer Than You Might Think
- JAK inhibitor tofacitinib for treating rheumatoid arthritis: from basic to clinical
- JAK inhibitor: tofacitinib, a new disease modifying anti-rheumatic drug
- JAK inhibitor; possibility and mechanism as a new disease modifying anti-rheumatic drug.
- JAK1-STAT3 blockade by JAK inhibitor SHR0302 attenuates inflammatory responses of adjuvant-induced arthritis rats and decreases Th17 and total B cells
- JAK-inhibitor tofacitinib suppresses interferon alfa production by plasmacytoid dendritic cells and inhibits arthrogenic and antiviral effects of interferon alfa
- Leptin stimulates tissue inhibitor of metalloproteinase-1 in human hepatic stellate cells respective roles of the Jak/Stat and JAK-Mediated H2O2-Dependent MAPK …
- LONG-TERM FOLLOW UP OF JAK INHIBITOR (JAKI) TREATED PATIENTS WITH MYELOFIBROSIS: IMPACT OF MOLECULAR ENHANCED INTEGRATED …
- Low dose CP-690,550 (tofacitinib), a pan-JAK inhibitor, accelerates the onset of experimental autoimmune encephalomyelitis by potentiating Th17 differentiation
- Mathematical modeling reveals alternative JAK inhibitor treatment in myeloproliferative neoplasms
- Methotrexate is a Jak/Stat pathway inhibitor
- Model based targeting of IL-6-induced inflammatory responses in cultured primary hepatocytes to improve application of the JAK inhibitor Ruxolitinib
- Models to Predict Response to JAK-inhibitor Therapy in Patients with Myelofibrosis
- Molecular and cellular mechanisms underlying the therapeutic efficacy of the combination of JAK inhibitor, ruxolitinib, PIM inhibitor, LGH447, and CDK4/6 inhibitor …
- Multifaceted intervention by the Hsp90 inhibitor ganetespib (STA-9090) in cancer cells with activated Jak/Stat signaling
- Myeloproliferative neoplasm in a thalassaemic patient: response to treatment with a JAK inhibitor
- Nephrotic syndrome in primary myelofibrosis with renal extramedullary hematopoiesis and glomerulopathy in the JAK inhibitor era
- New inhaled JAK inhibitor LAS194046 inhibits allergen-induced airway inflammation in Brown Norway rats
- Novartis JAK inhibitor provides marked and durable clinical benefits in patients with myelofibrosis, a rare, life-threatening blood cancer
- Novel inhaled pan-JAK inhibitor, LAS194046, reduces allergen-induced airway inflammation, late asthmatic response, and pSTAT activation in brown Norway rats
- Novel translational pharmacology approaches on dose reduction and alternative scheduling for the combination of JAK inhibitor, ruxolitinib, PIM inhibitor, LGH447 …
- OP0149 A phase 2B study of an oral JAK inhibitor ASP015K monotherapy in Japanese patients with moderate to severe rheumatoid arthritis
- OP0253 The JAK Inhibitor Tofacitinib Suppresses Synovial JAK1-STAT1 Signalling in Rheumatoid Arthritis
- P041 THE GUT-SELECTIVE, ORALLY ADMINISTERED, PAN-JAK INHIBITOR TD-1473 DEMONSTRATES FAVORABLE SAFETY, TOLERABILITY …
- P-177 Safety, Tolerability, and Pharmacokinetics of the Intestine-Restricted Oral Pan-JAK Inhibitor TD-1473 After Single and Multiple Oral Doses in Healthy Subjects
- P-269 A Combination Therapy of Selective MMP9 Inhibitor and JAK Inhibitors Is Efficacious in Mouse DSS Model of Colitis
- PD-009 A Phase 2B, multicenter, randomized, placebo-controlled dose-ranging trial of peficitinib, an oral JAK inhibitor, in patients with moderately-severely active UC
- Peficitinib, a JAK Inhibitor, in Combination With Limited Conventional Synthetic Disease‐Modifying Antirheumatic Drugs in the Treatment of Moderate‐to‐Severe …
- Peficitinib, a JAK Inhibitor, in the Treatment of Moderate‐to‐Severe Rheumatoid Arthritis in Patients With an Inadequate Response to Methotrexate
- Perspectives on the impact of JAK-inhibitor therapy upon inflammation-mediated comorbidities in myelofibrosis and related neoplasms
- Pfizer’s first-in-class JAK inhibitor pricey for rheumatoid arthritis market
- Pfizer’s JAK inhibitor hits goals in ulcerative colitis trial
- Pfizer’s JAK inhibitor sails through phase 3 in rheumatoid arthritis
- P-glycoprotein (ABCB1) and Breast Cancer Resistance Protein (ABCG2) restrict the brain penetration of the Janus family of tyrosine kinase (JAK) inhibitor CYT387
- Pharmacokinetics and pharmacodynamics of the dual syk/JAK inhibitor PRT062070 (cerdulatinib) in patients with advanced B-cell malignancies.
- Pharmacokinetics, safety and tolerability of ABT-494, a novel selective JAK 1 inhibitor, in healthy volunteers and subjects with rheumatoid arthritis
- Pharmacological properties of JTE-052: a novel potent JAK inhibitor that suppresses various inflammatory responses in vitro and in vivo
- Phase 1 open-label dose escalation study of the dual SYK/JAK inhibitor cerdulatinib (PRT062070) in patients with relapsed/refractory B-cell malignancies: Safety …
- Phase 3 trial of momelotinib (MMB) vs ruxolitinib (RUX) in JAK inhibitor (JAKi) naive patients with myelofibrosis (MF).
- Phase I/II Data Published in New England Journal of Medicine Demonstrate that Incyte JAK Inhibitor, INCB18424, Provides Marked and Durable Clinical …
- Phase II study of the JAK kinase inhibitor ruxolitinib in patients with refractory leukemias, including post myeloproliferative neoplasms (MPN) acute myeloid …
- Phase IIb dose‐ranging study of the oral JAK inhibitor tofacitinib (CP‐690,550) or adalimumab monotherapy versus placebo in patients with active rheumatoid arthritis …
- PHOSPHOSPECIFIC FLOW CYTOMETRY: PHARMACODYNAMIC MONITORING OF THE NOVEL JAK-INHIBITOR CP-690,550 IN KIDNEY TRANSPLANT PATIENTS …
- Potentiation of Nilotinib-mediated cell death in the context of the bone marrow microenvironment requires a promiscuous JAK inhibitor in CML
- Preclinical characterization of the Jak/Stat inhibitor SGI-1252 on skeletal muscle function, morphology, and satellite cell content
- Pre-Clinical Evaluation Of A Potent Janus Kinase (JAK) Inhibitor Designed For Topical Delivery In Severe Asthma
- Preclinical evaluation of HM-018, a potent and selective JAK inhibitor in the treatment of myloproliferative disorders
- Pre-Clinical Results of Islet Allo-Transplantation Using JAK Inhibitor as Replacement for Tacrolimus Widely Used Immunosuppressive Drug in Islet Transplantation in …
- Predictive models for splenic response to JAK-inhibitor therapy in patients with myelofibrosis
- Prevention of chronic renal allograft rejection by AS2553627, a novel JAK inhibitor, in a rat transplantation model
- Prevention of Lens Eithelial Cell Death After H2O2 Exposure Using JAK Inhibitor AG490 in Human Cataract
- PTU-001 Tofacitinib, an oral JAK inhibitor, in the treatment of ulcerative colitis: open-label, long-term extension study
- Pyridone 6, a pan-JAK inhibitor, ameliorates allergic skin inflammation of NC/Nga mice via suppression of Th2 and enhancement of Th17
- Rapid and Durable Responses with the SYK/JAK Inhibitor Cerdulatinib in a Phase 2 Study in Relapsed/Refractory Follicular Lymphoma-Alone or in Combination with …
- Replacement of mycophenolate mofetil with a JAK inhibitor, AS2553627, in combination with low-dose tacrolimus, for renal allograft rejection in non-human primates
- Results of a randomized study of the JAK inhibitor INC424 compared with best available therapy (BAT) in primary myelofibrosis (PMF), post-polycythemia vera …
- Results of a randomized study of the JAK inhibitor ruxolitinib (INC424) versus best available therapy (BAT) in primary myelofibrosis (PMF), post-polycythemia vera …
- Reversal of CD8 T-cell–mediated mucocutaneous graft-versus-host-like disease by the JAK inhibitor tofacitinib
- Role of Jak3-Stat6 and effect of JAK inhibitor on dendritic cells and its involvement in rheumatoid arthritis
- Safety and efficacy of the JAK inhibitor tofacitinib citrate in patients with alopecia areata
- Selective downregulation of JAK2 and JAK3 by an ATP-competitive pan-JAK inhibitor
- Selective Immunomodulation of Inflammatory Pathways in Keratinocytes by the Janus Kinase (JAK) Inhibitor Tofacitinib: Implications for the Employment of JAK …
- Serum human beta-defensin-2 is a possible biomarker for monitoring response to JAK inhibitor in psoriasis patients
- Simultaneous improvement of alopecia universalis and atopic dermatitis in a patient treated with a JAK inhibitor
- Successful treatment of palmoplantar pustulosis with rheumatoid arthritis, with tofacitinib: Impact of this JAK inhibitor on T-cell differentiation.
- Superior lethal activity of single agent BET protein PROTAC compared to bromodomain inhibitor or in combination with JAK inhibitor against post-myelofibrosis …
- Suppress for Success: A JAK Inhibitor for Adjunct Therapy of Tuberculosis
- Symptom assessment in patients with JAK inhibitor naive and JAK inhibitor failed myelofibrosis.
- Synthesis of pan-JAK Inhibitor PF-06263276
- Targeting compensatory MEK/ERK activation increases JAK inhibitor efficacy in myeloproliferative neoplasms
- The combination of JAK inhibitor, ruxolitinib, and PIM inhibitor, LGH447, in preclinical models of myeloproliferative neoplasia
- The combination of JAK inhibitor, ruxolitinib, pan-PIM inhibitor, LGH447, and CDK4/6 inhibitor, LEE011, in a preclinical mouse model of myeloproliferative neoplasia
- The dual Syk/JAK inhibitor cerdulatinib antagonizes B-cell receptor and microenvironmental signaling in chronic lymphocytic leukemia
- THE DUAL SYK/JAK INHIBITOR CERDULATINIB DEMONSTRATES RAPID AND DURABLE TUMOR RESPONSES IN A PHASE 2 STUDY IN RELAPSED …
- The dual SYK/JAK inhibitor cerdulatinib demonstrates rapid tumor responses in a phase 2 study in patients with relapsed/refractory B-and T-cell non-Hodgkin …
- The Effect of JAK-Inhibitor Tofacitinib on Intestinal Epithelial Barrier Function
- The effect of the JAK inhibitor CP-690,550 on peripheral immune parameters in stable kidney allograft patients
- The effect of the JAK2 inhibitor TG101209 against T cell acute lymphoblastic leukemia (T-ALL) is mediated by inhibition of JAK-STAT signaling and activation …
- The Effect of Verapamil, a P‐Glycoprotein Inhibitor, on the Pharmacokinetics of Peficitinib, an Orally Administered, Once‐Daily JAK Inhibitor
- The effects of a JAK inhibitor AG490 combined DDP on the cervical cancer model in nude mice
- The effects of JAK inhibitor therapy upon novel markers of thrombosis in myeloproliferative neoplasms
- The JAK inhibitor antcin H exhibits direct anticancer activity while enhancing chemotherapy against LMP1-expressed lymphoma
- The JAK inhibitor AZD1480 regulates proliferation and immunity in Hodgkin lymphoma
- The JAK inhibitor CP-690,550 (tofacitinib) inhibits TNF-induced chemokine expression in fibroblast-like synoviocytes: autocrine role of type I interferon
- The JAK Inhibitor CP‐690,550 Preserves the Function of CD4+CD25brightFoxP3+ Regulatory T Cells and Inhibits Effector T Cells
- The JAK inhibitor ruxolitinib reduces inflammation in an ILC3-independent model of innate immune colitis
- The JAK inhibitor tofacitinib ameliorates immune‑mediated liver injury in mice
- The JAK inhibitor tofacitinib for active rheumatoid arthritis: results from phase III trials
- The JAK inhibitor tofacitinib suppresses synovial JAK1-STAT signalling in rheumatoid arthritis
- The JAK inhibitor, tofacitinib, reduces the T cell stimulatory capacity of human monocyte-derived dendritic cells
- The JAK inhibitor, tofacitinib, rescues IFN-γ-induced barrier permeability in human colonoids and acts independent of tight junction protein expression changes in T84 …
- The JAK kinase inhibitor CP‐690,550 supresses the growth of human polycythemia vera cells carrying the JAK2V617F mutation
- The JAK-3 inhibitor CP-690550 is a potent anti-inflammatory agent in a murine model of pulmonary eosinophilia
- The JAK-Inhibitor Tofacitinib Rescues Human Intestinal Epithelial Cells and Colonoids from Cytokine-Induced Barrier Dysfunction
- The JAK-inhibitor, JAB/SOCS-1 selectively inhibits cytokine-induced, but not v-Src induced JAK–STAT activation
- The novel JAK inhibitor AZD1480 blocks STAT3 and FGFR3 signaling, resulting in suppression of human myeloma cell growth and survival
- The novel JAK inhibitor CYT387 suppresses multiple signalling pathways, prevents proliferation and induces apoptosis in phenotypically diverse myeloma …
- The novel JAK‐3 inhibitor CP‐690550 is a potent immunosuppressive agent in various murine models
- The pharmacokinetics, pharmacodynamics, and safety of baricitinib, an oral JAK 1/2 inhibitor, in healthy volunteers
- The possible mode of action of Tofacitinib, a JAK inhibitor
- The potent and lung-selective inhaled pan JAK inhibitor TD-8236 limits airway inflammation without affecting systemic immunity in mice
- The putative JAK-STAT inhibitor AG490 exacerbates LPS-fever, reduces sickness behavior, and alters the expression of pro-and anti-inflammatory genes in the rat …
- The safety and efficacy of a JAK inhibitor in patients with active rheumatoid arthritis: results of a double‐blind, placebo‐controlled phase IIa trial of three dosage levels …
- The selective Pan-Janus kinase (JAK) inhibitor VR588 demonstrates potent anti-inflammatory activity in a murine chronic house dust mite (HDM) model of …
- The SYK\JAK inhibitor cerdulatinib (PRT062070) shows promising preclinical activity in chronic lymphocytic leukemia by antagonising B-cell receptor and …
- The telomerase inhibitor imetelstat in patients (pts) with intermediate-2 or high-risk myelofibrosis (MF) previously treated with Janus kinase (JAK) inhibitor: A phase 2 …
- Therapeutic potential of Jak/Stat signal inhibition in prostate cancer by the JAK inhibitor AZD1480.
- THU0101 ASP015K: A Novel JAK Inhibitor Demonstrated Potent Efficacy in Adjuvant-Induced Arthritis Model in Rats
- THU0136 Cardiovascular safety findings in rheumatoid arthritis patients treated with tofacitinib (CP-690,550), a novel, oral JAK inhibitor
- THU0145 A multi-biomarker disease activity (MBDA) score measures rheumatoid arthritis disease activity in patients treated with the JAK inhibitor tofacitinib
- THU0185 Tofacitinib, An Oral JAK Inhibitor, in The Treatment of Rheumatoid Arthritis: Safety and Clinical and Radiographic Efficacy in Open-Label, Long-Term …
- THU0227 Pooled Analysis of Clinical Safety Data for ASP015K, a Novel JAK Inhibitor in Development for Treatment of Autoimmune Diseases
- THU0258 oral start: effects of the oral JAK inhibitor tofacitinib monotherapy versus methotrexate on patient-reported outcomes in the phase 3 oral start trial of active …
- Tofacitinib (Xeljanz): The First‐in‐Class JAK Inhibitor for the Treatment of Rheumatoid Arthritis
- Tofacitinib, a JAK inhibitor, inhibits human B cell activation in vitro
- Tofacitinib: Novel JAK inhibitor for RA
- Tofacitinib: The First Janus Kinase (JAK) inhibitor for the treatment of rheumatoid arthritis
- Tolerability and response of the novel SYK/JAK inhibitor cerdulatinib in a phase 2a study in relapsed/refractory peripheral t cell lymphoma (PTCL).
- Tumoricidal effects of the JAK inhibitor Ruxolitinib (INC424) on hepatocellular carcinoma in vitro
- VX‐509 (Decernotinib), an oral selective JAK‐3 inhibitor, in combination with methotrexate in patients with rheumatoid arthritis
- WITHDRAWN: Nephrotic syndrome in primary myelofibrosis with renal extramedullary hematopoiesis and glomerulopathy in the JAK inhibitor era.
- JAK-inhibitor-approved-for-ulcerative-colitis”>Xeljanz (Tofacitinib) Receives Expanded Indication, Becoming the First Oral JAK Inhibitor Approved for Ulcerative Colitis
- JAK-inhibitor-approved-for-patients-with-rheumatoid-arthritis”>Xeljanz XR (Tofacitinib) First Once-Daily Oral JAK Inhibitor Approved for Patients with Rheumatoid Arthritis
- JAK-inhibitor-now-approved-for-adults-with-active-psoriatic-arthritis”>Xeljanz/Xeljanz XR (Tofacitinib/Tofacitinib XR), an Oral JAK Inhibitor, Now Approved for Adults with Active Psoriatic Arthritis
- Blueberry and malvidin inhibit cell cycle progression and induce mitochondrial-mediated apoptosis by abrogating the Jak/Stat-3 signalling pathway
- Dysregulation of Jak/Stat genes by vasoactive intestinal peptide (VIP) in Salmonella-infected monocytes may inhibit its therapeutic potential in human sepsis
- Environmental toxicants inhibit neuronal JAK tyrosine kinase by mitochondrial disruption
- Gamma-Aminobutyric Acid Binds to GABAB Receptor to Inhibit Cholangiocarcinoma Cells Growth via the Jak/Stat3 Pathway
- gold nanoparticles using Euphrasia officinalisleaf extract to inhibit lipopolysaccharide-induced inflammation through NF-κB and Jak/Stat pathways in …
- gp130 associated molecule inhibit the association of JAK kinase with gp130
- Human immunodeficiency virus‐1 envelope glycoproteins and anti‐CD4 antibodies inhibit interleukin‐2‐induced Jak/Stat signalling in human CD4 T lymphocytes
- IFN-λs inhibit Hantaan virus infection through the JAK-STAT pathway and expression of Mx2 protein
- Indomethacin leads to poor prognoses through promoting the expression of PD-1 and PD-L2 via TRIF/NF-κB pathway and Jak/Stat3 pathway to inhibit TNF-α and …
- Inducing apoptosis to inhibit inflammatory proliferation of IL-6-induced fibroblast-like synoviocytes through modulating the activation of Jak/Stat and NF …
- Insulin potentiates Jak/Stat signaling to broadly inhibit flavivirus replication in insect vectors
- Iron Chelators and Hypoxia Mimetics Inhibit IFNγ-Mediated JAK-STAT Signaling
- JAK 2‐V 617 F‐mediated signalling is dependent on lipid rafts and statins inhibit JAK 2‐V 617 F‐dependent cell growth
- Jak/Stat Inhibitor Has Potential To Inhibit Intervertebral Disc Degeneration: o171
- Lambda-Interferons inhibit Herpes Simplex Virus Type 2 Replication in Human Cervical Epithelial Cells through Activation of Jak/Stat Pathway
- luteolin synergistically inhibit the proliferation of interleukin-1 β-induced fibroblast-like synoviocytes through regulating the activation of NF-κ B and JAK …
- Metformin and aspirin synergistically inhibit mTOR and Jak/Stat3 signaling pathway and induce cell death in pancreatic cancer cells
- miR-409 down-regulates JAK-Stat pathway to inhibit progression of liver cancer
- Myricitrin modulates NADPH oxidase-dependent ROS production to inhibit endotoxin-mediated inflammation by blocking the Jak/Stat1 and NOX2/p47phox …
- Nonstructural protein of severe fever with thrombocytopenia syndrome phlebovirus targets STAT2 and not STAT1 to inhibit type I interferon-stimulated JAK-STAT …
- Novel mechanisms to inhibit HIV reservoir seeding using JAK inhibitors
- Ovarian carcinoma cells inhibit T cell proliferation: suppression of IL-2 receptor β and γ expression and their JAK-STAT signaling pathway
- Pacritinib to inhibit Jak/Stat signaling in refractory metastatic colon and rectal cancer
- The Nucleoprotein and Phosphoprotein of Peste des Petits Ruminants Virus Inhibit Interferons Signaling by Blocking the JAK-STAT Pathway
- Varicella viruses inhibit interferon-stimulated JAK-STAT signaling through multiple mechanisms
- 1, 25 (OH) 2D3 suppresses proinflammatory responses by inhibiting Th1 cell differentiation and cytokine production through the Jak/Stat pathway
- Abstract# 2971: Benzyl isothiocyanate induces apoptosis in human pancreatic cancer cells by inhibiting Jak/Stat pathway
- ALA‐PDT alleviates the psoriasis by inhibiting JAK signaling pathway
- Angelica sinensis polysaccharide promotes apoptosis by inhibiting Jak/Stat pathway in breast cancer cells
- Aspirin increases ferroportin 1 expression by inhibiting hepcidin via the Jak/Stat3 pathway in interleukin 6-treated PC-12 cells
- Cadmium and mercury suppress cytokine receptor-mediated Jak/Stat activation by inhibiting mitochondrial function and increasing intracellular oxidative …
- Crocin promotes apoptosis of human skin cancer cells by inhibiting the Jak/Stat pathway
- Cryptotanshinone sensitizes antitumor effect of paclitaxel on tongue squamous cell carcinoma growth by inhibiting the Jak/Stat3 signaling pathway
- Curcumin improves the recovery of motor function and reduces spinal cord edema in a rat acute spinal cord injury model by inhibiting the Jak/Stat signaling pathway
- Dexmedetomidine protects against renal ischemia and reperfusion injury by inhibiting the Jak/Stat signaling activation
- Effect of Dishevelled 2 on apoptosis in rheumatoid arthritis fibroblast-like synoviocytes through inhibiting JAK-STAT pathway
- Effects of inhibiting JAK on invasion and metastasis of the human breast cancer cells through ERK signaling transduction pathway
- Effects of propofol on myocardial ischemia reperfusion injury through inhibiting the Jak/Stat pathway.
- Epigallocatechin-3-gallate ameliorates seawater aspiration-induced acute lung injury via regulating inflammatory cytokines and inhibiting Jak/Stat1 pathway in rats
- Esculetin Inhibits Proliferation, Invasion, and Migration of Laryngeal Cancer In Vitro and In Vivo by Inhibiting Janus Kinas (JAK)-Signal Transducer and …
- Essential oil of Artemisia argyi suppresses inflammatory responses by inhibiting Jak/Stats activation
- Feifukang ameliorates pulmonary fibrosis by inhibiting JAK-STAT signaling pathway
- Formononetin ameliorates high glucose‑induced endothelial dysfunction by inhibiting the Jak/Stat signaling pathway
- Genkwanin ameliorates adjuvant-induced arthritis in rats through inhibiting Jak/Stat and NF-κB signaling pathways
- Ginkgo biloba extract EGb761 attenuates brain death-induced renal injury by inhibiting pro-inflammatory cytokines and the SAPK and JAK-STAT signalings
- HEV ORF3 downregulatesCD14 and CD64 to impair macrophages phagocytosis through inhibiting Jak/Stat pathway
- IFN-CSP inhibiting hepatitis B virus in HepG2. 2.15 cells involves JAK-STAT signal pathway
- IFN-γ down-regulates ABCA1 expression by inhibiting LXRα in a Jak/Stat signaling pathway-dependent manner
- Interferon-gamma inhibits the neuronal differentiation of neural progenitor cells by inhibiting the expression of Neurogenin2 via the Jak/Stat1 pathway
- Ischemic postconditioning during reperfusion attenuates intestinal injury and mucosal cell apoptosis by inhibiting Jak/Stat signaling activation
- Knockdown of HE4 suppresses aggressive cell growth and malignant progression of ovarian cancer by inhibiting the Jak/Stat3 pathway
- Liraglutide Exerts Potential Anti-inflammatory Effect in Type 1 Diabetes by Inhibiting IFN-γ Production via Suppressing JAK-STAT Pathway.
- Losartan reduces myocardial interstitial fibrosis in diabetic cardiomyopathy rats by inhibiting Jak/Stat signaling pathway
- Lowly expressed EGFR-AS1 promotes the progression of preeclampsia by inhibiting the EGFR-Jak/Stat signaling pathway
- Matrine increases NKG2D ligand ULBP2 in K562 cells via inhibiting Jak/Stat3 pathway: A potential mechanism underlying the immunotherapy of matrine in …
- MicroRNA-210 promotes spinal cord injury recovery by inhibiting inflammation via the JAK-STAT pathway
- MiR-17 Regulates Prostate Cancer Cell Proliferation and Apoptosis Through Inhibiting JAK-STAT3 Signaling Pathway
- MiR-21 inhibitor improves locomotor function recovery by inhibiting IL-6R/JAK-STAT pathway-mediated inflammation after spinal cord injury in model of rat
- Oleanolic acid inhibiting the differentiation of neural stem cells into astrocyte by down-regulating Jak/Stat signaling pathway
- Phytosphingosine Derivatives Ameliorate Skin Inflammation by Inhibiting NF-κB and Jak/Stat Signaling in Keratincoytes and Mice
- Protein inhibitor of activated STAT (PIAS) negatively regulates the Jak/Stat pathway by inhibiting STAT phosphorylation and translocation
- Pyruvate Protects Against Intestinal Injury by Inhibiting the Jak/Stat Signaling Pathway in Rats With Hemorrhagic Shock
- Recombinant human brain natriuretic peptide ameliorates trauma-induced acute lung injury via inhibiting Jak/Stat signaling pathway in rats
- Simvastatin attenuated cardiac hypertrophy via inhibiting JAK-STAT pathways
- SOCS2 exacerbates myocardial injury induced by ischemia/reperfusion in diabetic mice and H9c2 cells through inhibiting the JAK-STAT-IGF-1 pathway
- The VHL tumor suppressor protein regulates tumorigenicity of U87-derived glioma stem-like cells by inhibiting the Jak/Stat signaling pathway
- TM‐233, a novel analog of 1′‐acetoxychavicol acetate, induces cell death in myeloma cells by inhibiting both Jak/Stat and proteasome activities
- 1693-P: Rapamycin Reduces Maternal Diabetes-Induced Neural Tube Defects by Suppressing Premature Senescence
- 17beta-estradiol attenuates TNF-α-induced premature senescence of nucleus pulposus cells through regulating the ROS/NF-κB pathway
- 2, 3, 7, 8-Tetrachlorodibenzo-P-dioxin (TCDD) induces premature senescence in human and rodent neuronal cells via ROS-dependent mechanisms
- 2, 3, 7, 8‐Tetrachlorodibenzo‐p‐dioxin induces premature senescence of astrocytes via WNT/β‐catenin signaling and ROS production
- 2.1 The centrosomal protein TACC3 controls paclitaxel sensitivity by modulating a premature senescence program
- 5-FU-injured bone marrow stromal cells initiate stress-induced premature senescence of hematopoietic cells
- 5-methoxytryptophan protects MSCs from stress induced premature senescence by upregulating FoxO3a and mTOR
- 68: Stress-induced premature senescence in airway epithelium and accelerated lung allograft aging
- A bioactive polysaccharide TLH-3 isolated from Tricholoma lobayense protects against oxidative stress-induced premature senescence in cells and mice
- A Comparative Analysis of Stress Granule Assembly in Replicative and Stress-Induced Premature Senescence
- A comparison of replicative senescence and doxorubicin-induced premature senescence of vascular smooth muscle cells isolated from human aorta
- A Highlights from MBoC Selection: Inhibition of nuclear factor-erythroid 2–related factor (Nrf2) by caveolin-1 promotes stress-induced premature senescence
- A Micro-RNA Connection in-Mediated Premature Senescence of Human Melanocytes
- A positive feedback loop between Pim-1 kinase and HBP1 transcription factor contributes to hydrogen peroxide-induced premature senescence and apoptosis
- A Possible Role of Stress-Induced Premature Senescence, SIPS, as a Producer of the Stress-Resistant Microenvironment
- A Preliminary Study on Relationship between Leaf Premature Senescence Characteristic and Leaf N Content, Roots Activity in Hybrid Rice during Grain Filling Stage …
- A quantitative chemiluminescent method for studying replicative and stress-induced premature senescence in cell cultures
- A role for mitochondrial oxidants in stress-induced premature senescence of human vascular smooth muscle cells
- A single cytosine deletion in the OsPLS1 gene encoding vacuolar-type H+-ATPase subunit A1 leads to premature leaf senescence and seed dormancy in rice
- A steroid like phytochemical Antcin M is an anti-aging reagent that eliminates hyperglycemia-accelerated premature senescence in dermal fibroblasts by …
- A system biology approach to provide a mechanistic understanding of radiation induced premature senescence in endothelial cells
- AB0088 Deficient Autophagy Induces Premature Senescence in Aging and Osteoarthritis
- Abiotic Stresses Intervene with ABA Signaling to Induce Destructive Metabolic Pathways Leading to Death: Premature Leaf Senescence in Plants
- Ablation of galectin-3 induces p27KIP1-dependent premature senescence without oncogenic stress
- Abnormal mitosis in hypertetraploid cells causes aberrant nuclear morphology in association with H2O2‐induced premature senescence
- Absence of premature senescence in Werner’s syndrome keratinocytes
- Abstract A60: Role of telomere dysfunction in the premature cellular senescence of Hutchinson‐Gilford progeria syndrome
- Abstract B36: Premature senescence is enhanced by PKCeta and its polymorphic variant V374I
- Abstract# 3472: HdmX overexpression inhibits oncogenic ras induced premature senescence.
- Accelerated premature stress-induced senescence of young annulus fibrosus cells of rats by high glucose-induced oxidative stress
- Accelerated Senescence of Cord Blood Endothelial Progenitor Cells From Premature Neonates is Driven by Sirt1 Decreased Expression
- Accumulation of Reactive Oxygen Species and Induction of Premature Senescence: Role of DDB2
- Acetyl‐11‐keto‐β‐boswellic acid triggers premature senescence via induction of DNA damage accompanied by impairment of DNA repair genes in hepatocellular …
- Actin-binding doliculide causes premature senescence in p53 wild type cells
- Activation of a cAMP Pathway and Induction of Melanogenesis Correlate with Association of p16INK4 and p27KIP1 to CDKs, Loss of E2F-Binding Activity, and Premature Senescence of Human Melanocytes
- Activation of a PGC-1-related coactivator (PRC)-dependent inflammatory stress program linked to apoptosis and premature senescence
- Activation of p38 and changes in mitochondria accompany autophagy to premature senescence-like phenotype switch upon chronic exposure to selenite in colon …
- Activation of p53 with Nutlin-3a radiosensitizes lung cancer cells via enhancing radiation-induced premature senescence
- Acute activation of AMP-activated protein kinase prevents H2O2-induced premature senescence in primary human keratinocytes
- Additive effects of C2-ceramide on paclitaxel-induced premature senescence of human lung cancer cells
- Adiponectin corrects premature cellular senescence and normalizes antimicrobial peptide levels in senescent keratinocytes
- Adiponectin prevents diabetic premature senescence of endothelial progenitor cells and promotes endothelial repair by suppressing the p38 MAP kinase/p16INK4A …
- Adiponectin suppresses UVB-induced premature senescence and hBD2 overexpression in human keratinocytes
- Adult Sox2+ stem cell exhaustion in mice results in cellular senescence and premature aging
- Advances in understanding leaf premature senescence and its molecular mechanism in rice
- Agents that cause DNA double strand breaks lead to p16INK4a enrichment and the premature senescence of normal fibroblasts
- Aging with ING: a comparative study of different forms of stress induced premature senescence
- Akt determines replicative senescence and oxidative or oncogenic premature senescence and sensitizes cells to oxidative apoptosis
- ALA-PDT elicits oxidative damage and apoptosis in UVB-induced premature senescence of human skin fibroblasts
- Altered myogenesis and premature senescence underlie human TRIM32-related myopathy
- AMPK-mediated downregulation of connexin43 and premature senescence of mesangial cells under high-glucose conditions
- An in vitro study on biological characteristics of bone marrow mesenchymal stem cells in microenvironment of premature senescence of nucleus pulposus cells
- Analysing the contribution of ATM/ATR pathway activation in establishing the premature senescence of E2F1/E2F2-/-bone-marrow-derived macrophages
- Analysis and gene mapping of rice premature senescence mutant zs.
- Analysis of mineral element content in premature senescence walnut leaves under drip irrigation and fertilization condition [J]
- Analysis on relationship among cotton premature senescence, red leaf disease and Alternaria leaf spot disease.
- Androgen receptor accelerates premature senescence of human dermal papilla cells in association with DNA damage
- Androgenic alopecia and stress-induced premature senescence by cumulative ultraviolet light exposure
- Angelica sinensis polysaccharides ameliorate stress-induced premature senescence of hematopoietic cell via protecting bone marrow stromal cells from oxidative …
- Ankyrin-B syndrome: enhanced cardiac function balanced by risk of cardiac death and premature senescence
- Anti-aging activity of kimchi during fermentation period against oxidative stress-induced premature senescence in cellular model
- Anti-aging effect of black rice against H2O2-induced premature senescence
- Anti-aging effects and mechanisms of kimchi during fermentation under stress-induced premature senescence cellular system
- Anti-aging effects of cyanidin under a stress-induced premature senescence cellular system
- Antioxidant-Dependent Prevention of H2O2-Induced Premature Senescence in Human Endometrial Stem Cells
- Anti-photoaging potential of Botulinum Toxin Type A in UVB-induced premature senescence of human dermal fibroblasts in vitro through decreasing senescence …
- Apoptosis changes and SA-beta galactosidase expression in stress-induced premature senescence (SIPS) model of human skin fibroblasts.
- Arsenic increases Pi-mediated vascular calcification and induces premature senescence in vascular smooth muscle cells
- Arsenite induces premature senescence via p53/p21 pathway as a result of DNA damage in human malignant glioblastoma cells
- Assessing the role of stress signalling via p38 MAP kinase in the premature senescence of Ataxia Telangiectasia and Werner syndrome fibroblasts
- Astragaloside exerts anti-photoaging effects in UVB-induced premature senescence of rat dermal fibroblasts through enhanced autophagy
- Attenuation of Replication Stress–Induced Premature Cellular Senescence to Assess Anti‐Aging Modalities
- Attenuation of TGF-β signaling suppresses premature senescence in a p21-dependent manner and promotes oncogenic Ras-mediated metastatic transformation in …
- Autophagic cell death and premature senescence: New mechanism of 5-fluorouracil and sulforaphane synergistic anticancer effect in MDA-MB-231 triple negative …
- Autophagy impairment induces premature senescence in primary human fibroblasts
- Autophagy inhibition switches low-dose camptothecin-induced premature senescence to apoptosis in human colorectal cancer cells
- Autophagy through 4EBP1 and AMPK regulates oxidative stress-induced premature senescence in auditory cells
- Autophagy: The missing link between non-enzymatically glycated proteins inducing apoptosis and premature senescence of endothelial cells?
- B56 INFLAMMATION AND VASCULAR PERMEABILITY: Cigarette Smoke (cs) Induces Premature Senescence In Highly Proliferative Endothelial Colony Forming …
- Bcl-2 activates a programme of premature senescence in human carcinoma cells
- Bcl-2 promotes premature senescence induced by oncogenic Ras
- Bcl-2 protects against oxidative stress while inducing premature senescence
- Beryllium induces premature senescence in human fibroblasts
- Bisdemethoxycurcumin increases Sirt1 to antagonize t-BHP-induced premature senescence in WI38 fibroblast cells
- Bisphosphonates induce premature senescence and impair proliferation and migration of normal human oral keratinocytes
- Bmal1-deficient mouse fibroblast cells do not provide premature cellular senescence in vitro
- BMP4-Smad signaling pathway mediates adriamycin-induced premature senescence in lung cancer cells
- B-myb rescues ras-induced premature senescence, which requires its transactivation domain
- Bone marrow-derived mesenchymal stem cells protected rat cardiomyocytes from premature senescence
- Branched-chain amino acids enhance premature senescence through mammalian target of rapamycin complex I-mediated upregulation of p21 protein
- BRE plays an essential role in preventing replicative and DNA damage-induced premature senescence
- Ca2+/Redox-Sensitive Tyrosine Kinase PYK2 Promotes Atherogenesis through OxLDL/ROS/p21-Dependent Premature Senescence and Cytokine Induction in …
- Ca2+/Redox-Sensitive Tyrosine Kinase PYK2 Promotes Atherogenesis Through OxLDL/ROS/p21-Dependent Premature Senescence in Endothelium
- Cancer Biology; Inhibition of NDRG1 expression induced premature senescence
- Cancer cell survival following DNA damage-mediated premature senescence is regulated by mammalian target of rapamycin (mTOR)-dependent Inhibition of sirtuin 1
- Cancer stem cells and escape from drug-induced premature senescence in human lung tumor cells: implications for drug resistance and in vitro drug screening …
- Carbon filter prevents ozone fleck and premature senescence of tobacco leaves
- Cardiolipin activates MAP kinases during premature senescence in normal human fibroblasts
- Cardiolipin induces premature senescence in normal human fibroblasts
- Cathepsin cleavage of sirtuin 1 in endothelial progenitor cells mediates stress-induced premature senescence
- Causes and Controlling Measures of Cotton Premature Senescence in Yangtze River Cotton Area [J]
- Caveolin‐1 deficiency induces premature senescence with mitochondrial dysfunction
- Caveolin-1 expression and stress-induced premature senescence in human intervertebral disc degeneration
- Caveolin-1 mediated p53 activation in stress induced premature senescence and its antagonistic pleiotropic implications in cancer
- CBX8 antagonizes the effect of Sirtinol on premature senescence through the AKT-RB-E2F1 pathway in K562 leukemia cells
- CBX8 suppresses Sirtinol-induced premature senescence in human breast cancer cells via cooperation with SIRT1
- CD34+ cells from patients with myelodysplastic syndrome present different p21 dependent premature senescence
- Cell cycle arrest by human cytomegalovirus 86-kDa IE2 protein resembles premature senescence
- Cell cycle regulation in H2O2-induced premature senescence of human diploid fibroblasts and regulatory control exerted by the papilloma virusE6 and E7 proteins
- Cell proliferation and amplifies long‐term temozolomide‐and radiation‐induced cytotoxicity in melanoma cells: A role for autophagy and premature senescence
- Cell-Free Culture Supernatant of Probiotic Lactobacillus fermentum Protects Against H2O2-Induced Premature Senescence by Suppressing ROS-Akt-mTOR Axis in …
- Cells deleted for Brca2 COOH terminus exhibit hypersensitivity to γ-radiation and premature senescence
- Cellular and molecular mechanisms of stress-induced premature senescence (SIPS) of human diploid fibroblasts and melanocytes
- Cellular Senescence and Premature Aging in Lung Diseases
- Cellular senescence in normal and premature lung aging
- Changes in levels of foliar carbohydrates and myo-inositol before premature leaf senescence of Populus nigra induced by a mixture of O3 and SO2
- Changes of the expression for genes related with senescence and the telomerase activity during cellular replicative and premature senescence in human embryonic …
- Characterization and fine mapping of the rice premature senescence mutant ospse1
- Characterization and fine-mapping of a novel premature leaf senescence mutant yellow leaf and dwarf 1 in rice
- Characterization and Mapping of a Novel Premature Leaf Senescence Mutant in Common Tobacco (Nicotiana tabacum L.)
- Chromosome aberrations and cellular premature senescence as radiation-induced sub-lethal effects: Implications for laser-driven charged-particle radiotherapy
- Chronic low dose rate ionizing radiation exposure induces premature senescence in human fibroblasts that correlates with up regulation of proteins involved in …
- Chronic NF-κB activation delays RasV12-induced premature senescence of human fibroblasts by suppressing the DNA damage checkpoint response
- Chronic Nucleoside Reverse Transcriptase Inhibitors Disrupt Mitochondrial Homeostasis and Promote Premature Endothelial Senescence
- Cilostazol inhibits oxidative stress–induced premature senescence via upregulation of Sirt1 in human endothelial cells
- Circular RNA expression profile in human fibroblast premature senescence after repeated ultraviolet B irradiations revealed by microarray
- Cisplatin-induced premature senescence with concomitant reduction of gap junctions in human fibroblasts
- c-Jun-deficient cells undergo premature senescence as a result of spontaneous DNA damage accumulation
- Coenzyme Q10 Alleviates Chronic Nucleoside Reverse Transcriptase Inhibitor-Induced Premature Endothelial Senescence
- Cofilin mediates actin destabilization and shape change in replicative senescence and stress-induced premature senescence
- Colonization of durum wheat (Triticum turgidum L. var. durum) culms exhibiting premature senescence (dead heads) associated with Fusarium pseudograminearum …
- Comparison of global DNA methylation profiles in replicative versus premature senescence
- Comparison of replicative senescence and stress‐induced premature senescence combining differential display and low‐density DNA arrays
- Comparison of the effects of 40% oxygen and two atmospheric absolute air pressure conditions on stress-induced premature senescence of normal human diploid …
- Comprehensive Evaluation of Soil Fertility in Premature Senescence Cotton Fields in the Yellow River Region
- Compromising the constitutive p16INK4a expression sensitizes human neuroblastoma cells to Hsp90 inhibition and promotes premature senescence
- Conditioned medium derived from human amniotic stem cells delays H2O2‑induced premature senescence in human dermal fibroblasts
- Constitutive Activation of rac1 Results in Mitochondrial Oxidative Stress and Induces Premature Endothelial Cell Senescence
- Contribution of mitochondrial dysfunction and oxidative stress to cellular premature senescence induced by antiretroviral thymidine analogues
- Contribution of p16INK4a and p21CIP1 pathways to induction of premature senescence of human endothelial cells: permissive role of p53
- Control of premature senescence for the high and stable output of cotton.
- Cooperative role between p21cip1/waf1 and p27kip1 in premature senescence in glandular proliferative lesions in mice
- Copper ability to induce premature senescence in human fibroblasts
- Cordyceps militaris extract protects human dermal fibroblasts against oxidative stress-induced apoptosis and premature senescence
- Co-regulation of p16INK4A and migratory genes in culture conditions that lead to premature senescence in human keratinocytes
- Correction: Adiponectin Suppresses UVB-Induced Premature Senescence and hBD2 Overexpression in Human Keratinocytes
- Correlation between senescence and DNA repair in cells from young and old individuals and in premature aging syndromes
- Corrigendum to’Autophagic cell death and premature senescence: New mechanism of 5-fluorouracil and sulforaphane synergistic anticancer effect in MDA-MB-231 …
- Cr (VI) induces premature senescence through ROS-mediated p53 pathway in L-02 hepatocytes
- Cristacarpin promotes ER stress-mediated ROS generation leading to premature senescence by activation of p21waf-1
- Curcumin attenuates hydrogen peroxide-induced premature senescence via the activation of SIRT1 in human umbilical vein endothelial cells
- Cyclic mechanical tension reinforces DNA damage and activates the p53-p21-Rb pathway to induce premature senescence of nucleus pulposus cells
- Cyclophosphamide induces premature senescence in normal human fibroblasts by activating MAP kinases
- Cytokinesis defects, polyploidy and premature senescence in SSeCKS/Gravin/AKAP12-null mouse embryo fibroblasts
- Cytoplasmic Retention of CDC6 Induces Premature Senescence in Immortalized Cells and Suppresses Tumor Formation in Mice
- Damaged DNA binding protein 2 in reactive oxygen species (ROS) regulation and premature senescence
- Davallialactone from mushroom reduced premature senescence and inflammation on glucose oxidative stress in human diploid fibroblast cells
- DDB2, an essential mediator of premature senescence
- DEC1, a basic helix-loop-helix transcription factor and a novel target gene of the p53 family, mediates p53-dependent premature senescence
- Deconstructing PML‐induced premature senescence
- Deficient autophagy induces premature senescence in aging and osteoarthritis
- Depletion of CSN5 inhibits Ras-mediated tumorigenesis by inducing premature senescence in p53-null cells
- Deregulation of hsa-miR-20b expression in TNF-α-induced premature senescence of human pulmonary microvascular endothelial cells
- D-galactose induces premature senescence of lens epithelial cells by disturbing autophagy flux and mitochondrial functions
- Diagnosis of premature senescence of cotton using SPAD value
- Differences in protein changes between stress‐induced premature senescence and replicative senescence states
- Differential protein expression in senescent human skin fibroblasts and stress induced premature senescence (SIPS) fibroblasts
- Diperoxovanadate can substitute for H2O2 at much lower concentration in inducing features of premature cellular senescence in mouse fibroblasts (NIH3T3)
- Discussion on Premature Senescence of Maize and Its Prevention Technology [J]
- Disorazole C1: A potent antimitotic agent that induces premature senescence
- Disruption of a Upf1-like helicase-encoding gene OsPLS2 triggers light-dependent premature leaf senescence in rice
- Dissecting the Regulatory Network of Leaf Premature Senescence in Maize (Zea mays L.) Using Transcriptome Analysis of ZmELS5 Mutant
- DNA deletion and impairment of mitochondrial biogenesis are mediated by reactive oxygen species in ionizing radiation-induced premature senescence
- Dominant Gene cplsr1 Corresponding to Premature Leaf Senescence Resistance in Cotton (Gossypium hirsutum L.)F
- Down regulation of CD147 boosts the premature senescence in human skin fibroblasts by destroying the redox balance and inhibiting klotho
- Down-regulation and decreased activity of cyclin-dependent kinase 2 in H2O2-induced premature senescence
- Down-regulation of Asymmetric Arginine Methylation During Replicative and H2O2-induced Premature Senescence in WI-38 Human Diploid Fibroblasts
- DP 4.08 P16 triggers premature senescence of congenital DM1 myoblasts
- Drug-induced premature senescence model in human dental follicle stem cells
- Dysfunction during Aging and Senescence: Effect of lipopolysaccharides on adipogenic potential and premature senescence of adipocyte progenitors
- Early loss of proliferative potential of human peritoneal mesothelial cells in culture: the role of p16INK4a-mediated premature senescence
- Effect of bisphenol A on stress-induced premature senescence
- Effect of lipopolysaccharides on adipogenic potential and premature senescence of adipocyte progenitors
- EFFECT OF MAGNETIC FIELD AND NANO-PARTICLES OFTITANIUM OXIDE (TIO2) ON SEED GERMINATION AND EARLYGROWTH CHARACTERISTICS OF AJOWAN (AMMI COPTICUM L.) IN PREMATURE SENESCENCE
- Effect of Maize Straw Return to Soil on Premature Senescence [J]
- Effect of rapamycin on high glucose-induced autophagy impairment, oxidative stress and premature senescence in rat mesangial cells in vitro
- Effect of removal of basal fruiting branches on some premature senescence characters of different cotton genotypes.
- Effect of removal of early squares on verticillium wilt and premature senescence in Bt transgenic cotton
- Effect of Saikokeishito, a Kampo medicine, on hydrogen peroxide-induced premature senescence of normal human dermal fibroblasts
- Effect of sulfated galactan from Porphyra haitanensis on H2O2-induced premature senescence in WI-38 cells
- Effect of water stress and nutrition stress on premature senescence-related enzyme activity in harvested broccoli
- Effects of Early Fruiting Branch Removal on Physiological Traits of Leaves Related to Premature Senescence, Yield, and Fiber Quality of Transgenic Bt Cotton
- Effects of estrogen on stress-induced premature senescence of vascular smooth muscle cells: a novel mechanism for the “time window theory” of menopausal …
- Effects of ginsenoside and Lycium barbarum polysaccharide on UVB irradiation-induced premature senescence of skin fibroblasts.
- Effects of Potassium Oligosaccharide Acids Effervescent Tablet on Premature Senescence and Yield of Wheat [J]
- Effects of removal of early fruiting branches on yield, fiber quality and premature senescence in Bt transgenic cotton
- Effects of sirolimus on ultraviolet B irradiation-induced premature senescence of skin fibroblasts
- Effects of the estrogen receptor on stress-induced premature senescence of vascular smooth muscle cells in vitro
- eIF2α phosphorylation bypasses premature senescence caused by oxidative stress and pro-oxidant antitumor therapies
- Elimination of protein aggregates prevents premature senescence in human trisomy 21 fibroblasts
- Endogenous transmembrane TNF-alpha protects against premature senescence in endothelial colony forming cells
- Enhanced elimination of oxidized guanine nucleotides inhibits oncogenic RAS-induced DNA damage and premature senescence
- Epigallocatechin gallate suppresses premature senescence of preadipocytes by inhibition of PI3K/Akt/mTOR pathway and induces senescent cell death by regulation …
- Epigenetic enhancement of p66Shc during cellular replicative or premature senescence
- Erratum. Adiponectin Prevents Diabetic Premature Senescence of Endothelial Progenitor Cells and Promotes Endothelial Repair by Suppressing the p38 MAP Kinase …
- Escape from premature senescence is not sufficient for oncogenic transformation by Ras
- Escherichia coli producing colibactin triggers premature and transmissible senescence in mammalian cells
- Essential role for premature senescence of myofibroblasts in myocardial fibrosis
- Establishment of H2O2‐Induced Premature Senescence in Human Fibroblasts Concomitant with Increased Cellular Production of H2O2
- Ethylene production and premature senescence of needles from fir trees (Abies alba)
- Evaluation of premature senescence and senescence biomarkers in carcinoma cells and xenograft mice exposed to single or fractionated irradiation
- Evidence that premature senescence affects photosynthetic decline of wheat flag leaves during growth in elevated carbon dioxide
- Exploiting “oncogene addiction” and “premature senescence” to design novel therapeutic strategies for the treatment of cancer
- Exposure to polycyclic aromatic hydrocarbons derived from vehicle exhaust gas induces premature senescence in mouse lung fibroblast cells
- Expression of catalytically active telomerase does not prevent premature senescence caused by overexpression of oncogenic Ha-Ras in normal human fibroblasts
- Expression of Clusterin suppresses Cr (VI)-induced premature senescence through activation of PI3K/AKT pathway
- Expression of senescence-associated miR-34c and SIRT1 in premature senescence of human skin fibroblasts induced by ultraviolet B
- Expression of β-catenin in oxidative stress-induced premature senescence of human skin fibroblasts
- Extension of Life Span and Delay of Stress–Induced Premature Senescence of Trabecular Meshwork (TM) Cells Incubated at Low Oxygen Tension
- FGFR3 signaling induces a reversible senescence phenotype in chondrocytes similar to oncogene-induced premature senescence
- Fibroblast growth factor 21 delayed endothelial replicative senescence and protected cells from H2O2-induced premature senescence through SIRT1
- Fibroblast Stimulation of Blood Vessel Development and Cancer Cell Invasion in a Subrenal Capsule Xenograft Model: Stress-Induced Premature Senescence Does Not Increase Effect1
- FP258 VNN1 mediates renal maladaptive repair after AKI by inducing premature senescence of renal tubular cells
- From the Hayflick mosaic to the mosaics of ageing.: Role of stress-induced premature senescence in human ageing
- Fullerene derivatives induce premature senescence: A new toxicity paradigm or novel biomedical applications
- Fullerenol Protects Human Retinal Pigment Epithelial Cells from Oxidative-Stress-Induced Premature Senescence Model in vitro
- Fullerenol protects retinal pigment epithelial cells from oxidative stress–induced premature senescence via activating SIRT1
- Fullerenol Protects RPE cells from Oxidative-stress Induced Premature Senescence via Activation of SIRT1
- Gadd45b deficiency impairs G2/M cell cycle progression leading to premature senescence
- Gadd45b deficiency promotes premature senescence and skin aging
- Gardenia jasminoides extract-capped gold nanoparticles reverse hydrogen peroxide-induced premature senescence
- Gefitinib induces premature senescence in non-small cell lung cancer cells with or without EGFR gene mutation
- Gene expression and regulation in H2O2-induced premature senescence of human foreskin fibroblasts expressing or not telomerase
- Gene mapping of starch accumulation and premature leaf senescence in the ossac3 mutant of rice
- Genetic analysis and fine mapping of a premature leaf senescence mutant in rice (Orzya sativa L.).
- Genetic analysis and high-resolution mapping of a premature senescence gene Pse(t) in rice (Oryza sativa L.)
- Genetic analysis of biochemical traits in short season upland cotton with no premature senescence
- Genetic and physio-biochemical characterization of a novel premature senescence leaf mutant in rice (Oryza sativa L.)
- Genetic diseases of premature aging as models of senescence
- Genetic effects and diagnosis of premature senescence of leaf in upland cotton.
- Ginsenoside Rg1 attenuates Busulfan-induced premature senescence
- Ginsenoside Rg1 delays tert-butyl hydroperoxide-induced premature senescence in human WI-38 diploid fibroblast cells
- Ginsenoside Rg1 protects human fibroblasts against psoralen-and UVA-induced premature senescence through a telomeric mechanism
- Glucosamine attenuates hydrogen peroxide-induced premature senescence in human retinal pigment epithelial cells in vitro
- Glucose utilization via glycogen phosphorylase sustains proliferation and prevents premature senescence in cancer cells
- Glutathione depletion induces ferroptosis, autophagy, and premature cell senescence in retinal pigment epithelial cells
- Glycated collagen I induces premature senescence-like phenotypic changes in endothelial cells
- Glyoxal‐induced premature senescence in human fibroblasts
- GP 9 04 Premature senescence of myoblasts in oculopharyngeal muscular dystrophy
- Growth kinetics rather than stress accelerate telomere shortening in cultures of human diploid fibroblasts in oxidative stress‐induced premature senescence
- Guiqi polysaccharide protects the normal human fetal lung fibroblast WI-38 cells from H2O2-induced premature senescence
- GW24-e0410 Stress-induced premature senescence in primary human umbilical vein endothelial cells
- GW25-e2369 Lipoic acid inhibits oxidative stress-induced premature senescence via upregulation of Sirt1 in human umbilical vascular endothelial cells
- GW25-e4428 Exogenous Hydrogen Sulfide Delays Nicotinamide-Induced Premature Senescence via SIRT1 pathway in Human Umbilical Vein Endothelial Cells
- Haploinsufficiency for BRCA1 leads to cell-type-specific genomic instability and premature senescence
- Heat shock induces apoptosis in human embryonic stem cells but a premature senescence phenotype in their differentiated progeny
- Helicobacter pylori-induced premature senescence of extragastric cells may contribute to chronic skin diseases
- Heme oxygenase-1 and interleukin-11 are overexpressed in stress-induced premature senescence of human WI-38 fibroblasts induced by tert-butylhydroperoxide …
- Hepatitis B virus X protein overcomes stress-induced premature senescence by repressing p16INK4a expression via DNA methylation
- Hepatitis C virus Core protein overcomes stress-induced premature senescence by down-regulating p16 expression via DNA methylation
- HEREDITARY PREMATURE SENESCENCE OF THE RABBIT I. CHROmC FOR~; G~ m~ RAL FEATURES
- Hereditary premature senescence of the rabbit: I. Chronic form; general features
- HEREDITARY PREMATURE SENESCENCE OF THE RABBIT: II. ACUTE FORM; GENERAL FEATURES
- Heterogeneity in premature senescence by oxidative stress correlates with differential DNA damage during the cell cycle
- HIF1α delays premature senescence through the activation of MIF
- High doses of synthetic antioxidants induce premature senescence in cultivated mesenchymal stem cells
- High intensity ras signaling induces premature senescence by activating p38 pathway in primary human fibroblasts
- High-magnitude compression accelerates the premature senescence of nucleus pulposus cells via the p38 MAPK-ROS pathway
- Histological evidence of oxidative stress and premature senescence in preterm premature rupture of the human fetal membranes recapitulated in vitro
- Histone H4 lysine 16 hypoacetylation is associated with defective DNA repair and premature senescence in Zmpste24-deficient mice
- Histone modifications contribute to cellular replicative and hydrogen peroxide-induced premature senescence in human embryonic lung fibroblasts
- HIV antiretroviral therapy drugs induce premature senescence and altered physiology in HUVECs
- Human electronegative LDL induces mitochondrial dysfunction and premature senescence of vascular cells in vivo
- Human fibroblast cells are resistant to low levels of DNA double-strand break induced apoptosis and subsequently undergo drug-induced premature senescence
- Human lipodystrophies linked to mutations in A-type lamins and to HIV protease inhibitor therapy are both associated with prelamin A accumulation, oxidative …
- Human umbilical cord-derived mesenchymal stromal cells protect against premature renal senescence resulting from oxidative stress in rats with acute kidney …
- Hydrogen sulfide delays nicotinamide-induced premature senescence via upregulation of SIRT1 in human umbilical vein endothelial cells
- Hyperoxia-induced premature senescence requires p53 and pRb, but not mitochondrial matrix ROS
- Hypoxia reoxygenation induces premature senescence in neonatal SD rat cardiomyocytes1
- Identification and characterization of secretory proteins during ionizing radiation-induced premature senescence
- Identification and comparative analysis of premature senescence leaf mutants in rice (Oryza sativa L.)
- Identification of 30 protein species involved in replicative senescence and stress‐induced premature senescence
- Identification of a novel E3 ubiquitin ligase that is required for suppression of premature senescence in Arabidopsis
- Identification of p38MAPK-dependent genes with changed transcript abundance in H2O2-induced premature senescence of IMR-90 hTERT human fibroblasts
- Identification of p53-dependent genes potentially involved in UVB-mediated premature senescence of human skin fibroblasts using siRNA technology
- Identification of Premature Senescence Cells in the Brain of the HIV-1 Transgenic Rat (HIV-TG Rat)
- IGF-1 rescues human intervertebral annulus cells from in vitro stress-induced premature senescence
- IGF-1 Rescues Human Intervertebral Annulus Cells in a Novel Model of in Vitro Stress-Induced Premature Senescence: Paper# 19.
- IL-6-STAT3 signaling and premature senescence
- Impact of ER stress-regulated ATF4/p16 signaling on the premature senescence of renal tubular epithelial cells in diabetic nephropathy
- Impact of ozone on the activity and quantity of ribulose bisphosphate carboxylase/oxygenase in potato foliage and its relation to premature senescence.
- Impact of premature senescence on radiosensitivity measured by high throughput cell-based assays
- In memoriam Olivier Toussaint–Stress-induced premature senescence and the role of DNA damage
- Increased abundance of cytoplasmic and nuclear caveolin 1 in human diploid fibroblasts in H2O2-induced premature senescence and interplay with …
- Increased chemo-sensitivity by knockdown coilin expression involved acceleration of premature cellular senescence in HeLa cells
- Increasing the complexity of respiratory syncytial virus infection: Reactive oxygen species, DNA damage, and premature senescence
- Induction of EMT by twist proteins as a collateral effect of tumor-promoting inactivation of premature senescence
- Induction of premature senescence by hsp90 inhibition in small cell lung cancer
- Induction of premature senescence by single and fractionated irradiation in human cancer cell line and xenografted mice model
- Induction of premature senescence in cardiomyocytes by doxorubicin as a novel mechanism of myocardial damage
- Induction of premature senescence in cardiomyocytes by oxidative stress as a novel mechanism of myocardial dysfunction
- Induction of premature senescence in human fibroblasts through endoplasmic reticulum stress: protection by phenolic diterpenes
- Induction of premature senescence in human lung cancer by fungal immunomodulatory protein from Ganoderma tsugae
- Induction of premature senescence program by an inhibitor of histone deacetylase sodium butyrate in normal and transformed rat fibroblasts
- Induction of stress induced premature senescence by sirtuin-7 inhibition: a novel mechanism for multi drug resistance
- Inflammatory cytokine TNF-α promotes premature senescence of rat nucleus pulposus cells through PI3K/Akt signaling pathway
- Influence of RNA interference in p53 gene on the expressions of genes involved in ultraviolet B-induced premature senescence and photocarcinogenesis in human …
- Inhibition of nuclear factor-erythroid 2–related factor (Nrf2) by caveolin-1 promotes stress-induced premature senescence
- Inhibition of stress induced premature senescence in presenilin-1 2 mutated cells with water soluble Coenzyme Q10 Q2
- Inhibition of stress induced premature senescence in presenilin-1 mutated cells with water soluble Coenzyme Q10
- Inhibition of the K+ Channel KCa3. 1 Reduces TGF-b1-Induced Premature Senescence
- Inhibition of the K+ Channel KCa3. 1 Reduces TGF-β1-Induced Premature Senescence, Myofibroblast Phenotype Transition and Proliferation of Mesangial Cells
- Inhibition of thioredoxin reductase 1 by caveolin 1 promotes stress‐induced premature senescence
- Inhibition of Twist1-mediated invasion by Chk2 promotes premature senescence in p53-defective cancer cells
- Inhibition of vascular smooth muscle cells premature senescence with rutin attenuates and stabilizes diabetic atherosclerosis
- Initiation of premature senescence by Bcl-2 in hypoxic condition
- Inonotus obliquus protects against oxidative stress-induced apoptosis and premature senescence
- Ins and outs of tumour control: when a potentially dangerous cell can’t be repaired, it must be either stopped or killed. Premature senescence of cancerous cells is one …
- Insulin-like growth factor binding proteins 4 and 7 released by senescent cells promote premature senescence in mesenchymal stem cells
- Insulin-like growth factor-1 attenuates oxidative stress-induced hepatocyte premature senescence in liver fibrogenesis via regulating nuclear p53–progerin …
- Interaction of nematodes with Fusarium moniliforme, incitant of premature senescence of maize
- Interleukin-1β induced premature senescence of articular chondrocytes
- Interleukin-6 Induces Premature Senescence Involving Signal Transducer and Activator of Transcription 3 and Insulin-Like Growth Factor-Binding Protein 5
- Intestinal stem cells acquire premature senescence and senescence associated secretory phenotype concurrent with persistent DNA damage after heavy ion …
- Investigation of premature senescence and red leaf occurrence in different cotton varieties.
- Involvement of abscisic acid in PSII photodamage and D1 protein turnover for light-induced premature senescence of rice flag leaves
- Involvement of MAP-kinase cascades in regulation of sodium-butyrate-induced premature senescence
- Involvement of MAP-kinase cascades into the regulation of sodium butyrate induced premature cell senescence
- Ionizing irradiation inhibits keloid fibroblast cell proliferation and induces premature cellular senescence
- Ionizing radiation and busulfan induce premature senescence in murine bone marrow hematopoietic cells
- Ionizing radiation-mediated premature senescence and paracrine interactions with cancer cells enhance the expression of syndecan 1 in human breast …
- Is post-traumatic stress disorder associated with premature senescence? A review of the literature
- Isolation and physiological characteristics of a premature senescence mutant in rice (Oryza sativa L.)
- JNK inhibition sensitizes tumor cells to radiation-induced premature senescence via Bcl-2/ROS/DDR signaling pathway
- Klotho RNAi induces premature senescence of human cells via a p53/p21 dependent pathway
- Knockdown of IL-8 Provoked Premature Senescence of Placenta-Derived Mesenchymal Stem Cells
- Knocking out the gene RLS1 induces hypersensitivity to oxidative stress and premature leaf senescence in rice
- Lack of vitamin D receptor causes stress-induced premature senescence in vascular smooth muscle cells through enhanced local angiotensin-II signals
- Large CTG repeats trigger p16-dependent premature senescence in myotonic dystrophy type 1 muscle precursor cells
- Lipid mediators of autophagy in stress-induced premature senescence of endothelial cells
- Long noncoding RNA H19 mediates melatonin inhibition of premature senescence of c‐kit+ cardiac progenitor cells by promoting miR‐675
- Long-term arsenite exposure induces premature senescence in B cell lymphoma A20 cells
- Long-term exposure to TNF-α leads human skin fibroblasts to a p38 MAPK-and ROS-mediated premature senescence
- Losartan inhibits STAT1 activation and protects human glomerular mesangial cells from angiotensin II induced premature senescence
- Loss of Cdh1 Triggers Premature Senescence in Part via Activation of Both the RB/E2F1 and the CLASPIN/CHK1/P53 Tumor Suppressor Pathways
- LPS-induced premature osteocyte senescence: Implications in inflammatory alveolar bone loss and periodontal disease pathogenesis
- Lutein suppresses hyperglycemia‐induced premature senescence of retinal pigment epithelial cells by upregulating SIRT1
- MAD2 depletion triggers premature cellular senescence in human primary fibroblasts by activating a p53 pathway preventing aneuploid cells propagation
- Malvidin protects WI-38 human fibroblast cells against stress-induced premature senescence
- Management practices to control premature senescence in Bt cotton
- Mapping mechanisms and charting the time course of premature cell senescence and apoptosis: lysosomal dysfunction and ganglioside accumulation in endothelial …
- Mapping of post-flowering drought resistance traits in grain sorghum: association between QTLs influencing premature senescence and maturity
- Mapping QTL for drought stress-induced premature senescence and maturity in cowpea [Vigna unguiculata (L.) Walp.]
- Maternal Characteristics versus Egg Size and Energy Density: Do Stocked Lake Trout in Lake Ontario Experience Premature Reproductive Senescence?
- Measurements of hydrogen peroxide induced premature senescence: senescence-associated β-galactosidase and DNA synthesis index in human diploid fibroblasts …
- Mechanism of premature senescence of cotton plants grown under drip irrigation and mulch film: plant growth response and nutrient status.
- Mechanism of radiation induced premature senescence of bone marrow stromal cells: experiment with murine bone marrow stromal cells
- Mechanisms of premature cell senescence
- Meiotic drive by the Y-linked D gene in Aedes aegypti (L.)(Diptera: Culicidae) is associated with disruption of spermiogenesis, leading to premature senescence of …
- Melatonin reverses H2O2‐induced premature senescence in mesenchymal stem cells via the SIRT1‐dependent pathway
- Melatonin suppresses doxorubicin‐induced premature senescence of A549 lung cancer cells by ameliorating mitochondrial dysfunction
- Mesenchymal stem cells from rats with chronic kidney disease exhibit premature senescence and loss of regenerative potential
- Meteorological Conditions and Countermeasures for Premature Senescence of Insect-Resistant Cotton [J]
- Microparticles released by senescent endothelial cells promote premature endothelial senescence associated with an impaired NO formation and oxidative …
- MicroRNA regulation of ionizing radiation-induced premature senescence
- MicroRNA-34a (miR-34a) Mediates Retinal Endothelial Cell Premature Senescence through Mitochondrial Dysfunction and Loss of Antioxidant Activities
- Microtubule binding and disruption and induction of premature senescence by disorazole C1
- Mild mitochondrial uncoupling prevents premature senescence in human dermal fibroblasts
- MiR-23a-depressed autophagy is a participant in PUVA-and UVB-induced premature senescence
- Mitochondrial DNA deletion and impairment of mitochondrial biogenesis by reactive oxygen species in ionizing radiation-induced premature senescence
- Mitoxantrone ability to induce premature senescence in human dental pulp stem cells and human dermal fibroblasts
- MMP-9 inhibition provokes premature senescence resulting in inhibition of medulloblastoma tumor growth via p16 INK4A and mitogen-activated protein kinase …
- Modelling human ageing: Role of telomeres in stress-induced premature senescence and design of anti-ageing strategies
- Modulation of PPARγ provides new insights in a stress induced premature senescence model
- Molecular basis for premature senescence induced by surfactants in normal human cells
- Molecular biomarkers indicate precocious in vitro senescence in fibroblasts from SAMP6 mice: evidence supporting a murine model of premature senescence …
- Molecular mechanisms of premature senescence in cotton
- Molecular models of aging: comparative analysis of gene signatures in replicative senescence and stress induced premature senescence
- Monoamine oxidase‐A is a novel driver of stress‐induced premature senescence through inhibition of parkin‐mediated mitophagy
- MOZ increases p53 acetylation and premature senescence through its complex formation with PML
- Mussel oligopeptides protect human fibroblasts from hydrogen peroxide (H2O2)-induced premature senescence
- NaDC3 induces premature cellular senescence by promoting transport of krebs cycle intermediates, increasing NADH, and exacerbating oxidative damage
- NADPH oxidase NOX1 is involved in activation of protein kinase C and premature senescence in early stage diabetic kidney
- NCOA4 depletion leads to replication stress and premature senescence
- Nek6 suppresses the premature senescence of human cancer cells induced by camptothecin and doxorubicin treatment
- Nevirapine induces growth arrest and premature senescence in human cervical carcinoma cells
- Nijmegen breakage syndrome fibroblasts expressing the C-terminal truncated NBNp70 protein undergo p38/MK2-dependent premature senescence
- Not Affect the Overexpression of p21WAF‐1 after Exposure of IMR‐90 hTERT Fibroblasts to a Sublethal Concentration of H2O2 Leading to Premature Senescence
- Novel contributors and mechanisms of cellular senescence in hypertension-associated premature vascular aging
- Novel mechanisms of sublethal oxidant toxicity: induction of premature senescence in human fibroblasts confers tumor promoter activity
- Nuclear swelling occurs during premature senescence mediated by MAP kinases in normal human fibroblasts
- Obesity and type-2 diabetes as inducers of premature cellular senescence and ageing
- Occludin‐mediated premature senescence is a fail‐safe mechanism against tumorigenesis in breast carcinoma cells
- Ochratoxin A induced premature senescence in human renal proximal tubular cells
- Oct4 suppresses IR‑induced premature senescence in breast cancer cells through STAT3-and NF‑κB-mediated IL‑24 production
- Oncogenic ras induces premature senescence in endothelial cells: role of p21Cip1/Waf1
- Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a
- Osthole Delays Tert-Butyl Hydroperoxide-Induced Premature Senescence in Neural Stem Cells
- Overactive Arginase Causes Mitochondrial Dysfunction and Premature Endothelial Cell Senescence during Diabetic Retinopathy
- Overexpression of apolipoprotein J in human fibroblasts protects against cytotoxicity and premature senescence induced by ethanol and tert …
- Overexpression of CHMP7 from rapeseed and Arabidopsis causes dwarfism and premature senescence in Arabidopsis
- Overexpression of SIRT6 in porcine fetal fibroblasts attenuates cytotoxicity and premature senescence caused by D-galactose and tert-butylhydroperoxide
- Oxidative DNA damage causes premature senescence in mouse embryonic fibroblasts deficient for Krüppel‐like factor 4
- Oxidative stress and premature senescence in corneal endothelium following penetrating keratoplasty in an animal model
- Oxidative stress induces premature senescence by stimulating caveolin-1 gene transcription through p38 mitogen-activated protein kinase/Sp1–mediated activation of …
- Oxidative stress-induced inhibition of Sirt1 by caveolin-1 promotes p53-dependent premature senescence and stimulates the secretion of interleukin 6 (IL-6)
- Oxidative stress-induced premature senescence dysregulates VEGF and CFH expression in retinal pigment epithelial cells: implications for age-related …
- Oxidative stress-induced premature senescence in Wharton’s jelly-derived mesenchymal stem cells
- OXIDIZED LDL INDUCES STRESS-INDUCED PREMATURE SENESCENCE IN CULTURED BOVINE ARTICULAR CHONDROCYTES
- Oxygen-sensing Nox4 generates genotoxic ROS to induce premature senescence of nucleus pulposus cells through MAPK and NF-κB pathways
- P. 106 Thrombospondin 1 mediates transforming growth factor beta induced premature senescence in primary glioblastoma cells
- P16 INK4a Deletion Ameliorated Renal Tubulointerstitial Injury in a Stress-induced Premature Senescence Model of Bmi-1 Deficiency
- P161: Adiponectin suppresses UVB-induced premature senescence and hBD2 overexpression by blocking p38, JNK/SAPK MAPK signaling in human normal …
- P196: Adiponectin ameliorate cellular premature senescence and restitute abnormal increase of antimicrobial peptide level in senescent keratinocyte
- P2-03-05: Attenuation of TGF-beta Signaling Suppresses Premature Senescence in a p21-Dependent Manner and Promotes Oncogenic ras-Mediated Metastatic …
- p21 WAF1 and hypoxia/reoxygenation-induced premature senescence of H9c2 cardiomyocytes
- p41-Arc, a regulatory subunit of Arp2/3 complex, can induce premature senescence in the absence of p53 and Rb
- p53 and ATF-2 partly mediate the overexpression of COX-2 in H2O2-induced premature senescence of human fibroblasts
- Paeonol protects against premature senescence in endothelial cells by modulating Sirtuin 1 pathway
- Pak4 induces premature senescence via a pathway requiring p16INK4/p19ARF and mitogen-activated protein kinase signaling
- Partial uncoupling of oxidative phosphorylation induces premature senescence in human fibroblasts and yeast mother cells
- Pathways of aging: comparative analysis of gene signatures in replicative senescence and stress induced premature senescence
- Pegylated IFN-α sensitizes melanoma cells to chemotherapy and causes premature senescence in endothelial cells by IRF-1-mediated signaling
- Performance and Mechanisms of Premature Senescence in Cotton
- Persistent DNA damage-induced premature senescence alters the functional features of human bone marrow mesenchymal stem cells
- Persistent DNA damage‐induced premature senescence alters the functional features of human bone marrow mesenchymal stem cells
- PFG acted as an inducer of premature senescence in TIG-1 normal diploid fibroblast and an inhibitor of mitosis in the HeLa cells
- Pharmacological DNA-PK inhibition induces ATM/p53 dependent premature senescence with immunomodulatory phenotype in irradiated cancer cells
- Phenotypic characterization and fine mapping of mps1, a premature leaf senescence mutant in rice (Oryza sativa L.)
- Photosynthesis and chloroplast ultra-structure characteristics of flag leaves for a premature senescence rice mutant.
- PHYSIOLOGICAL PARAMETERS IN RELATION TO PREMATURE SENESCENCE IN WINTER WHEAT (TRITICUM AESTIVUM)[J]
- Placental telomere shortening in stillbirth: a sign of premature senescence?
- PML is induced by oncogenic ras and promotes premature senescence
- PML regulates p53 acetylation and premature senescence induced by oncogenic Ras
- Polymerase I and transcript release factor (PTRF)/cavin-1 is a novel regulator of stress-induced premature senescence
- PPM1B depletion induces premature senescence in human IMR-90 fibroblasts
- Prelamin A accumulation in endothelial cells induces premature senescence and functional impairment
- Prelamin a accumulation induced by hiv protease inhibitors or lamin a mutations triggers premature senescence and calcification of vascular smooth muscle cells
- Prelamin accumulation in primary endothelial cells induces premature senescence and activation
- Preliminary Study on Identification Indexes of the Anti-premature Senescence at Wheat Seed Germination Stage
- Premature aging/senescence in cancer cells facing therapy: good or bad?
- Premature B-cell senescence as a consequence of chronic immune activation: Implications for vaccination of immune compromised individuals
- Premature cardiac senescence in DahlS. Z-Leprfa/Leprfa rats as a new animal model of metabolic syndrome
- Premature cell senescence in human skin: dual face in chronic acquired pigmentary disorders
- Premature cellular senescence induced by pyocyanin, a redox-active Pseudomonas aeruginosa toxin
- Premature immune senescence in children with MS: Too young to go steady
- Premature leaf senescence 3, encoding a methyltransferase, is required for melatonin biosynthesis in rice
- Premature leaf senescence modulated by the Arabidopsis PHYTOALEXIN DEFICIENT4 gene is associated with defense against the phloem-feeding green peach …
- Premature lung aging and cellular senescence in the pathogenesis of idiopathic pulmonary fibrosis and COPD/emphysema
- Premature mitochondrial senescence and related ultrastructural changes during lung carcinogenesis modulation by curcumin and resveratrol
- Premature senescence activation in DLD‑1 colorectal cancer cells through adjuvant therapy to induce a miRNA profile modulating cellular death
- Premature senescence and cellular phenotype transformation of mesangial cells induced by TGF-B1
- Premature senescence and increased TGFβ signaling in the absence of Tgif1
- Premature Senescence in Cells From Patients With Autosomal Recessive Hypercholesterolemia (ARH) Evidence for a Role for ARH in Mitosis
- Premature senescence in cultured skin fibroblasts from subjects with cystic fibrosis
- Premature senescence in human breast cancer and colon cancer cells by tamoxifen-mediated reactive oxygen species generation
- Premature senescence in human diploid fibroblasts induced by oxidative stress and by stimulations with the pro-inflammatory cytokines. A review.
- Premature senescence in plants along a motorway
- Premature senescence in primary muscle cultures of myotonic dystrophy type 2 is not associated with p16 induction
- Premature Senescence in Primary Muscle Cultures of Myotonic Dystrophy Type 2 Is Not Associated With p16 Induction (P2. 047)
- Premature senescence induced by DNA demethylating agent (Decitabine) as therapeutic option for malignant pleural mesothelioma
- Premature Senescence Induced by Ionizing Radiation Requires AKT Activity and Reactive Oxygen Species in Glioma
- Premature senescence involving p53 and p16 is activated in response to constitutive MEK/MAPK mitogenic signaling
- Premature senescence is a major response to DNA cross-linking agents in BRCA1-defective cells: implication for tailored treatments of BRCA1 mutation carriers
- Premature senescence is a primary fail-safe mechanism of ERBB2-driven tumorigenesis in breast carcinoma cells
- Premature senescence of balding dermal papilla cells in vitro is associated with p16INK4a expression
- Premature senescence of cardiac fibroblasts and atrial fibrosis in patients with atrial fibrillation
- Premature senescence of circulating T cells in HCV-chronically infected patients (105.41)
- Premature senescence of cotton (Gossypium hirsutum L.)–Predominantly a potassium disorder caused by an imbalance of source and sink
- Premature senescence of cotton: current developments
- Premature Senescence of Cotton—The Future of Crop Nutrition Problems?
- Premature senescence of endothelial cells upon chronic exposure to TNFα can be prevented by N-acetyl cysteine and plumericin
- Premature senescence of endothelial cells: Methusaleh’s dilemma
- Premature senescence of highly proliferative endothelial progenitor cells is induced by tumor necrosis factor-α via the p38 mitogen-activated protein kinase pathway
- Premature senescence of human endothelial cells induced by inhibition of glutaminase
- Premature senescence of mesothelial cells is associated with non-telomeric DNA damage
- Premature Senescence of Naïve CD4+ T-Cells in Systemic Lupus Erythematosus
- Premature senescence of skin fibroblasts from insulin-dependent diabetic patients with kidney disease
- Premature senescence of T cells in long-term survivors of renal transplantation
- Premature senescence of T lymphocytes from patients with β-thalassemia major
- Premature senescence of T-cell subsets in axial spondyloarthritis
- Premature senescence of the immune system in rheumatoid arthritis and multiple sclerosis patients.
- Premature senescence of vascular cells is induced by HIV protease inhibitors: implication of prelamin A and reversion by statin
- Premature senescence, endothelial turnover and accelerated atherosclerosis in SLE: the relationship between circulating endothelial cells, telomere length and …
- Premature T cell senescence in Ovx mice is inhibited by repletion of estrogen and medicarpin: a possible mechanism for alleviating bone loss
- Premature T cell senescence in pediatric CKD
- Premature vascular senescence in metabolic syndrome: Could it be prevented and reversed by a selenorganic antioxidant and peroxynitrite scavenger ebselen?
- Prevention and reversal of premature endothelial cell senescence and vasculopathy in obesity-induced diabetes by ebselen
- Prevention of premature senescence requires JNK regulation of Bcl-2 and reactive oxygen species
- Probucol inhibits JAK2−STAT pathway activation and protects human glomerular mesangial cells from tert-butyl hydroperoxide induced premature senescence
- Profile gene expression of H_ (2) O_ (2)-induced premature senescence of human fibroblasts
- Profile of P66SHC expression and histone modifications in replicative cell senescence and oxidative-stress induced premature senescence
- Progerin-induced replication stress facilitates premature senescence in Hutchinson-Gilford progeria syndrome
- Program of premature senescence is not induced by sodium butyrate in transformants with JNK1, 2 knockout
- Progress in molecular mechanism underlying plant premature senescence
- Promising markers for the detection of premature senescence tumor cells induced by ionizing radiation: Cathepsin D and eukaryotic translation elongation factor 1
- Propagation Of Stress-Induced Premature Senescence In Culture Of Human Endometrial Stem Cells: Paracrine Effect Of Igf-Binding Protein 3
- Protective potential of mistletoe (Viscum album coloratum) against oxidative stress and cellular premature senescence
- Proteome oxidative carbonylation during oxidative stress-induced premature senescence of WI-38 human fibroblasts
- Pseudomonas pyocyanin inhibits wound repair by inducing premature cellular senescence: role for p38 mitogen-activated protein kinase
- Psoralen plus UVA (PUVA) induced premature senescence as a model for stress-induced premature senescence
- PTEN status switches cell fate between premature senescence and apoptosis in glioma exposed to ionizing radiation
- Purple sweet potato color inhibits endothelial premature senescence by blocking the NLRP3 inflammasome
- QTL mapping for premature senescence and related physiological traits in Wheat
- Quantitative proteomic analysis reveals induction of premature senescence in human umbilical vein endothelial cells exposed to chronic low‐dose rate gamma …
- Radiation-induced premature cellular senescence involved in glomerular diseases in rats
- Radiation-induced premature senescence is associated with specific cytogenetic changes
- RAP2.6L overexpression delays waterlogging induced premature senescence by increasing stomatal closure more than antioxidant enzyme activity
- Rapamycin increases radiosensitivity of cancer cells by induction of premature senescence.
- Rat notochordal cells undergo premature stress-induced senescence by high glucose
- RB maintains quiescence and prevents premature senescence through upregulation of DNMT1 in mesenchymal stromal cells
- Real space flight travel is associated with ultrastructural changes, cytoskeletal disruption and premature senescence of HUVEC
- Reasons of cotton premature senescence in Xinjiang and related prevention and control techniques.
- Receptor for advanced glycation end-products promotes premature senescence of proximal tubular epithelial cells via activation of endoplasmic reticulum stress …
- REDD1 protects osteoblast cells from gamma radiation-induced premature senescence
- Reducing mammary cancer risk through premature stem cell senescence
- Reductions in the number of mid-sized antral follicles are associated with markers of premature ovarian senescence in dairy cows
- Regiospecific Synthesis of Ring A Fused Withaferin A Isoxazoline Analogues: Induction of Premature Senescence by W-2b in Proliferating Cancer Cells
- Regrowth of Human Dermal Fibroblasts after 8-MOP plus UVA Treatment Implications for Stress-Induced Premature Senescence and Replicative Cellular …
- Regulation and role of miRNA and target genes in cell cycle during oxidative stress-induced premature senescence in mesenchymal stem cells
- Regulation of arginine methylation in endothelial cells: role in premature senescence and apoptosis
- Regulation of Respiration and the Oxygen Diffusion Barrier in Soybean Protect Symbiotic Nitrogen Fixation from Chilling-Induced Inhibition and Shoots from Premature Senescence
- Regulation of Subsoiling on Premature Senescence of Corn [J]
- Regulation of the Promyelocytic Leukemia Protein and Its Role in Premature Senescence
- Release and suppression of caspases by gamma-tocotrienol prevent apoptosis and delay aging in stress-induced premature senescence of skin fibroblasts
- Repeated exposure of human skin fibroblasts to UVB at subcytotoxic level triggers premature senescence through the TGF-β1 signaling pathway
- Repeated exposure of mouse dermal fibroblasts at a sub-cytotoxic dose of UVB leads to premature senescence: a robust model of cellular photoaging
- Replicative senescence and oxidant‐induced premature senescence: beyond the control of cell cycle checkpoints
- Repression of the SUMO‐specific protease Senp1 induces p53‐dependent premature senescence in normal human fibroblasts
- Reprogramming suppresses premature senescence phenotypes of Werner syndrome cells and maintains chromosomal stability over long-term culture
- Research progress of premature senescence in cotton
- Research Progress on Premature Senescence of Hybrid Rice [J]
- Research Survey of Cot-ton Premature Senescence [J]
- Restoring SIRT6 expression in Hutchinson-Gilford progeria syndrome cells impedes premature senescence and formation of dysmorphic nuclei
- Resveratrol enhances ionizing radiation-induced premature senescence in lung cancer cells
- Resveratrol induced premature senescence and inhibited epithelial-mesenchymal transition of cancer cells via induction of tumor suppressor Rad9
- Resveratrol induced premature senescence is associated with DNA damage mediated SIRT1 and SIRT2 down-regulation
- Resveratrol induces premature senescence in lung cancer cells via ROS-mediated DNA damage
- Resveratrol relieves hydrogen peroxide-induced premature senescence associated with SIRT1 in human mesenchymal stem cells
- Resveratrol, but not dihydroresveratrol, induces premature senescence in primary human fibroblasts
- Retraction for Roy et al.,“DDB2, an Essential Mediator of Premature Senescence”
- Rich fraction, and tocopherol in enhancing collagen synthesis and inhibiting collagen degradation in stress-induced premature senescence model of human diploid …
- Ripe areca nut extract arrests the cultivated normal human oral keratinocyte in G1/S phase and modulates the premature senescence
- Role of in Replicative Senescence and DNA Damage-Induced Premature Senescence in p53-Deficient Human Cells
- Role of Notch expression in premature senescence of murine bone marrow stromal cells
- Role of p16INK4a and BMI-1 in oxidative stress-induced premature senescence in human dental pulp stem cells
- Role of p38 MAPK pathway in BMP4-mediated Smad-dependent premature senescence in lung cancer cells
- Role of p38alpha kinase in activation of premature senescence program in transformed mouse fibroblasts
- Role of Prion protein in premature senescence of human fibroblasts
- Role of progerin-induced telomere dysfunction in HGPS premature cellular senescence
- ROS‐generating oxidases N ox1 and N ox4 contribute to oncogenic R as‐induced premature senescence
- Salidroside protects against premature senescence induced by ultraviolet B irradiation in human dermal fibroblasts
- Salidroside protects human fibroblast cells from premature senescence induced by H2O2 partly through modulating oxidative status
- SCID dogs: similar transplant potential but distinct intra-uterine growth defects and premature replicative senescence compared with SCID mice
- Screening of senescence-associated genes with specific DNA array reveals the role of IGFBP-3 in premature senescence of human diploid fibroblasts
- Selection of identification indexes of anti-premature senescence at seed germination stage in cucumis melon.
- Senescence and death of primitive cells and myocytes lead to premature cardiac aging and heart failure
- Senescence-messaging secretome factors trigger premature senescence in human endometrium-derived stem cells
- Sequential Activation of the MEK-Extracellular Signal-Regulated Kinase and MKK3/6-p38 Mitogen-Activated Protein Kinase Pathways Mediates Oncogenic ras-Induced Premature Senescence
- Shikonin induces apoptosis, necrosis, and premature senescence of human A549 lung cancer cells through upregulation of p53 expression
- Single base substitution in OsCDC48 is responsible for premature senescence and death phenotype in rice
- Single exposure of human fibroblasts (WI‐38) to a sub‐cytotoxic dose of UVB induces premature senescence
- Sirt1 modulates premature senescence-like phenotype in human endothelial cells
- SIRT1 protects against emphysema via FOXO3-mediated reduction of premature senescence in mice
- SIRTain regulators of premature senescence and accelerated aging
- SnoN functions as a tumour suppressor by inducing premature senescence
- Sodium butyrate do not induce the program of premature senescence in transformants with JNK1, 2 knockout
- SORBS2 and TLR3 induce premature senescence in primary human fibroblasts and keratinocytes
- SRSF2 is required for sodium butyrate-mediated p21WAF1 induction and premature senescence in human lung carcinoma cell lines
- Stathmin/Op18 depletion induces genomic instability and leads to premature senescence in human normal fibroblasts
- Stem Cell Factor Inhibits Premature Senescence of Megakaryocytes during ex vivo Expansion of Human Cord Blood CD34+ Cells Using Thrombopoietin
- Stem cell injury and premature senescence
- Stress factor–dependent differences in molecular mechanisms of premature cell senescence
- Stress induced premature senescence: a new culprit in ovarian tumorigenesis?
- Stress-induced (premature) senescence
- Stress‐induced Premature Senescence (SIPS)
- Stress-induced premature senescence and replicative senescence are different phenotypes, proteomic evidence
- Stress-induced premature senescence and tissue ageing
- Stress-induced premature senescence as a mechanism of nucleoside reverse transcriptase inhibitor-induced endothelial dysfunction (547.18)
- Stress-induced premature senescence as alternativetoxicological method for testing the long-term effectsof molecules under development in the industry
- Stress‐induced premature senescence in BJ and hTERT‐BJ1 human foreskin fibroblasts
- Stress-induced premature senescence in hTERT-expressing ataxia telangiectasia fibroblasts
- Stress-induced premature senescence in mononuclear cells from patients on long-term hemodialysis
- Stress-induced premature senescence of dermal papilla cells compromises hair follicle epithelial-mesenchymal interaction
- Stress-induced premature senescence of endothelial and endothelial progenitor cells
- Stress-induced premature senescence of endothelial cells.
- Stress-induced premature senescence of endothelial cells: a perilous state between recovery and point of no return
- Stress-induced premature senescence or stress-induced senescence-like phenotype: one in vivo reality, two possible definitions?
- Stress-induced premature senescence program activated in the mesenchymal stem cells by antioxidant treatments
- Stress-Induced Premature Senescence Promotes Proliferation by Activating the SENEX and p16INK4a/Retinoblastoma (Rb) Pathway in Diffuse Large B-Cell …
- Stress-induced premature senescence upregulates the expression of …
- Stress-induced premature senescence. Essence of life, evolution, stress, and aging.
- Stress-Induced Premature Senescence: Another Mechanism Involved in the Process of Accelerated Aging in Chronic Obstructive Pulmonary Disease
- Stress-induced premature senescence: from biomarkers to likeliness of in vivo occurrence
- Stress‐induced premature senescence: implications in anti‐tumor pharmacology
- Studies on biochemical assistant breeding technology of earliniess without premature senescence of the short–season upland cotton
- Study on the Parameters of Digital Images of Diagnosis on Cotton Premature senescence Grade [J]
- Study on the replicative and premature senescence induced by hydrogen peroxide of human embryonic lung fibroblasts
- SU5416 Induces Premature Senescence and Inhibits Proliferation of Endothelial Progenitor Cells From Patients With AMD
- SU5416 induces premature senescence in endothelial progenitor cells from patients with age-related macular degeneration
- Sublethal doses of surfactants induce premature senescence in normal human skin cells
- Sublethal heat shock induces premature senescence rather than apoptosis in human mesenchymal stem cells
- Sublethal oxidative stress induces the premature senescence of human mesenchymal stem cells derived from endometrium
- Supplemental Data Article Akt Determines Replicative Senescence and Oxidative or Oncogenic Premature Senescence and Sensitizes Cells to Oxidative Apoptosis
- Suppression of autophagy dysregulates the antioxidant response and causes premature senescence of melanocytes
- Suppression of Premature Senescence and Promotion of Metastatic Transformation: Role of Reduced TGF-Beta Signaling in Human Cancer Progression
- Suppression of the DHX9 helicase induces premature senescence in human diploid fibroblasts in a p53-dependent manner
- Suppression of thioredoxin-1 induces premature senescence in normal human fibroblasts
- Sustained inhibition of oxidative phosphorylation impairs cell proliferation and induces premature senescence in human fibroblasts
- Telomerase positive human diploid fibroblasts are resistant to replicative senescence but not premature senescence induced by chemical reagents
- Telomere shortening in stillbirth: a sign of premature placental senescence
- TGF-β Induces Premature and Replicative Senescence in Cancer Cells
- The ability of E1A to rescue ras-induced premature senescence and confer transformation relies on inactivation of both p300/CBP and Rb family proteins
- The adipokine visfatin/nampt induces premature senescence and telomere damage in human endothelial cells
- The antioxidative defense system is involved in the premature senescence in transgenic tobacco (Nicotiana tabacum NC89)
- The centrosomal protein TACC3 controls paclitaxel sensitivity by modulating a premature senescence program
- The chromatin-associated Phf12 protein maintains nucleolar integrity and prevents premature cellular senescence
- The definition of chemiluminescence intensity in experimental model of premature senescence
- The determination of chemiluminescence intensity in an experimental model of premature senescence
- The Effect of CpTI Cotton on Main Diseases and Premature Senescence
- The Effect of Stress Induced Premature Senescence on the Expression of Heterogeneous RibonucleoIeoprotein
- The expression and effect of microRNA-33 in the H2O2-induced premature senescence of NIH/3T3 cells
- The function of CUX1 in oxidative DNA damage repair is needed to prevent premature senescence of mouse embryo fibroblasts
- The gene expression profile of psoralen plus UVA-induced premature senescence in skin fibroblasts resembles a combined DNA-damage and stress-induced cellular …
- The HBP1 transcriptional repressor participates in RAS-induced premature senescence
- The inflammatory cytokine TNF-α promotes the premature senescence of rat nucleus pulposus cells via the PI3K/Akt signaling pathway
- The influence of polyethylene film mulch on the growth and the premature senescence of flue-cured tobacco on the coast of the Inland Sea.
- The inhibition of Nek6 function sensitizes human cancer cells to premature senescence upon serum reduction or anticancer drug treatment
- The involvement of epigenetic silencing of Foxa2 in cellular replicative and premature senescence induced by hydrogen peroxide
- The matrikine N-acetylated proline-glycine-proline induces premature senescence of nucleus pulposus cells via CXCR1-dependent ROS accumulation and …
- The Mph1 helicase can promote telomere uncapping and premature senescence in budding yeast
- The obtaining of transgenic cottons resistant to premature senescence
- The PI3K/Akt/mTOR pathway is implicated in the premature senescence of primary human endothelial cells exposed to chronic radiation
- The possible mechanism of cotton premature senescence under drip irrigation below mulch film-From the perspective of growth and nutrients.
- The PPARδ-mediated inhibition of angiotensin II-induced premature senescence in human endothelial cells is SIRT1-dependent
- The preconditioning of berberine suppresses hydrogen peroxide-induced premature senescence via regulation of Sirtuin 1
- The problems of premature senescence in occupational lung diseases
- The redox-sensitive induction of the local angiotensin system promotes both premature and replicative endothelial senescence: preventive effect of a standardized …
- The research about comparison of biological characteristics between replicative cell senescence and oxidative-stress induced premature senescence
- The role of cellular senescence in Werner syndrome: toward therapeutic intervention in human premature aging
- The role of p21 in ionizing radiation induced premature senescence
- The role of p38 kinase in the activation of the premature senescence program in transformed mouse fibroblasts
- The SCFFBXO46 ubiquitin ligase complex mediates degradation of the tumor suppressor FBXO31 and thereby prevents premature cellular senescence
- The STAT3-IGFBP5 axis is critical for IL-6/gp130-induced premature senescence in human fibroblasts
- THE STUDY ON THE SUSCEPTILITY TO APOPTOSIS OF YOUNG CELLS BEFORE AND AFTER BEING INDUCDE PREMATURE SENESCENCE
- The Sturgeon Ovarian Liquid and the Perch Roe Extract are Able to Enhance the Recovery of the Fibroblasts after their Stress-induced Premature Senescence
- The suppressed proliferation and premature senescence by ganciclovir in p53-mutated human non-small-lung cancer cells acquiring herpes simplex virus-thymidine …
- The thyroid hormone receptor β induces DNA damage and premature senescence
- Therapeutic and space radiation exposure of mouse brain causes impaired DNA repair response and premature senescence by chronic oxidant production
- Therapeutic doses of doxorubicin induce premature senescence of human mesenchymal stem cells derived from menstrual blood, bone marrow and adipose tissue
- Therapeutic efficacy of Kangen‐karyu against H2O2‐induced premature senescence
- Thrombospondin 1 mediates transforming growth factor beta induced premature senescence in primary glioblastoma cells
- Time-dependently expressed markers and the characterization for premature senescence induced by ionizing radiation in MCF7
- TLK286, a novel glutathione analog prodrug, induces irreversible G2 cell cycle arrest and premature senescence
- Tocotrienol-Rich Fraction (TRF) Treatment Promotes Proliferation Capacity of Stress-Induced Premature Senescence Myoblasts and Modulates the Renewal of …
- Tospo viral infection instigates necrosis and premature senescence by micro RNA controlled programmed cell death in Vigna unguiculata
- Transcription factor Sp1 prevents TRF2ΔBΔM-induced premature senescence in human diploid fibroblasts
- Transcriptional factor HBP1 targets P16INK4A, upregulating its expression and consequently is involved in Ras-induced premature senescence
- Transcriptional up-regulation of antioxidant genes by PPARδ inhibits angiotensin II-induced premature senescence in vascular smooth muscle cells
- Transcriptome analysis of a premature leaf senescence mutant of common wheat (Triticum aestivum L.)
- Transcriptome Analysis of Gene Expression Patterns Potentially Associated with Premature Senescence in Nicotiana tabacum L.
- Transcriptome and proteome analysis in human senescent fibroblasts and fibroblasts undergoing premature senescence induced by repeated sublethal …
- Transcriptomic profiling suggests a role for IGFBP5 in premature senescence of endothelial cells after chronic low dose rate irradiation
- Transfection with human adenovirus type 5 early-region 1A protects the primary human fibroblasts from ras-induced premature senescence in vitro
- Transient Increased Extracellular Release of H2O2 during Establishment of UVB‐Induced Premature Senescence
- Transient postnatal overfeeding causes liver stress-induced premature senescence in adult mice
- Treatment-sensitive premature renal and heart senescence in hypertension
- TZAP plays an inhibitory role in the self-renewal of porcine mesenchymal stromal cells and is implicated the regulation of premature senescence via the p53 …
- Ultrastructural and genetic characterization of a mutant exhibiting starch accumulation and premature leaf senescence in Medicago sativa
- Ultraviolet B exposure triggers premature senescence in human skin fibroblasts.
- Unbalanced consumption of vitamins and premature senescence.
- Upregulation of annexin A2 in H2O2-induced premature senescence as evidenced by 2D-DIGE proteome analysis
- UV light induces premature senescence in Akt1-null mouse embryonic fibroblasts by increasing intracellular levels of ROS
- UVB-induced premature senescence of human diploid skin fibroblasts
- Versican/PG-M assembles hyaluronan into extracellular matrix and inhibits CD44-mediated signaling toward premature senescence in embryonic fibroblasts
- Whey Protein Attenuates Angiotensin II-Primed Premature Senescence of Vascular Smooth Muscle Cells through Upregulation of SIRT1
- Wild-type p53-induced phosphatase 1 (Wip1) forestalls cellular premature senescence at physiological oxygen levels by regulating DNA damage response signaling …
- WITHDRAWN: Hexavalent chromium induces premature senescence through reactive oxygen species-mediated p53 pathway in L-02 hepatocytes
- YB-1 is important for late-stage embryonic development, optimal cellular stress responses, and the prevention of premature senescence
- Zinc finger protein 637 protects cells against oxidative stress-induced premature senescence by mTERT-mediated telomerase activity and telomere …
- α5β1 integrin antagonists reduce chemotherapy‐induced premature senescence and facilitate apoptosis in human glioblastoma cells
- 1, 25 dihydroxyvitamin‐D3 modulates JAK–STAT pathway in IL‐12/IFNγ axis leading to Th1 response in experimental allergic encephalomyelitis
- 106: Gain of glycosylation in MSMD patients reveals the key role of galectins and lipid nanodomains in IFN-γ receptor assembly and Jak/Stat signaling
- 108. Versican G1 Domain Stimulates Adenoviral Transgene Expression In A Jak/Stat Dependent Manner
- 124. Regulation of SOCS3 expression by prostaglandin, prolactin and growth hormone: challenging the Jak/Stat signalling dogma
- 126. Jak/Stat signalling in folliculogenesis
- 136 Theurapeutic Targeting Of JAK-Stat Signalling Pathways Responsible For Vascular Restenosis In Type 2 Diabetes Mellitus
- 142 Can JAK 2 Inhibitors Improve Uip In Rheumatoid Arthritis Patients? Food For Thought!
- 15-Deoxy-12, 14-prostaglandin J2 inhibits INF-γ-induced Jak/Stat1 signalling pathway activation and IP-10/CXCL10 expression in mesangial cells
- 15-Deoxy-Δ12, 14-Prostaglandin J2 regulates leukemia inhibitory factor signaling through JAK-STAT pathway in mouse embryonic stem cells
- 175 Pathway Enrichment Analysis Of Acute Myeloid Leukemia Pathogenesis: A Focus On JAK-Stat Signalling Pathway
- 1993P JAK-Stat Inhibitor Overcomes Interferon Γ-Reduced, Nk Cell-Mediated Cytotoxicity In Non-Small-Cell Lung Cancer Cells
- 242 A Phase Iii Randomised Placebo-Controlled Double-Blind Study Of Upadacitinib (Abt-494), A Selective JAK-1 Inhibitor, In Patients With Active Rheumatoid Arthritis …
- 25‐Hydroxyvitamin D3‐Enhanced Ptpn2 Positively Regulates Periodontal Inflammation Through The Jak/Stat Pathway In Human Oral Keratinocytes And A Mouse …
- 278 Jak/Stat3 SIGNALING PROMOTES SOMATIC CELL REPROGRAMMING BY EPIGENETIC REGULATION
- 2-Amino-1-Methyl-6-Phenylimidazo (4, 5-B) Pyridine (Phip) Induces Gene Expression Changes In Jak/Stat And Mapk Pathways Related To Inflammation …
- 2O Met Activation In Lung Cancer Up-Regulates Pd-L1 Expression Independently Of JAK-Stat Pathway, Promoting An Immunosuppressive Phenotype
- 3 The JAK-Stat Pathway
- 3.3 Jak/Stat-Pathway-A Case Study of the Modular Petri Net Modeling Concept
- 309-Lb: Cell-Permeable Truncated Socs3 Competitively Inhibits The Interaction Between Endogenous Socs3 And Leptin Receptor (Obr) To Overcome Leptin Resistance On Jak/Stat Signaling
- 327 PHARMACOLOGICAL INHIBITION OF Jak/Stat SIGNALING PREVENTS HIGH-GLUCOSE-INDUCED UP-REGULATION OF ENDOTHELIN-1 …
- 3B, A Novel Photosensitizer, Inhibits Glycolysis And Inflammation Via Mir-155-5P And Breaks The Jak/Stat3/Socs1 Feedback Loop In Human Breast Cancer Cells
- 5 (S)-hydroxyeicosatetraenoic acid stimulates DNA synthesis in human microvascular endothelial cells via activation of Jak/Stat and phosphatidylinositol 3-kinase …
- 5-aminoimidazole-4-carboxamide-1-β-D-ribofuranoside induces astroglial differentiation of neural stem cells via activating Jak/Stat3 pathway independently …
- 6 JAK Kinases in Leukemias
- 63: HYDROGEN SULFIDE PROTECTS AGAINST IRI THROUGH THE JAK-STAT PATHWAY IN AN IN VIVO MODEL OF IRI
- 6-Bromoindirubin-3′-oxime induces apoptosis of human melanoma cells associated with inhibition of Jak/Stat3 signaling
- 6-Bromoindirubin-3′-oxime inhibits Jak/Stat3 signaling and induces apoptosis of human melanoma cells
- 6-Hydroxy-3-O-Methyl-Kaempferol 6-O-Glucopyranoside Potentiates The Anti-Proliferative Effect Of Interferon Α/Β By Promoting Activation Of The Jak/Stat Signaling By …
- 7: SOLVING THE QUESTION OF PROTECTION: HYDROGEN SULFIDE CONFERS PROTECTION FROM IRI VIA ACTIVATION OF THE JAK-STAT PATHWAY
- 78: Therapeutic inhibition of Gp130/Jak/Stat3-dependent cytokine signaling suppresses WNT-dependent colon cancer formation
- 81 JAK-Stat Signalling Is Critical For Inner Cell Mass Development In Bovine Blastocysts
- 8‐Methoxypsoralen Protects Bovine Mammary Epithelial Cells Against Lipopolysaccharide‐Induced Inflammatory Injury Via Suppressing Jak/Stat And Nf‐Κb Pathway
- A Model Of Myeloproliferative Neoplasm Reveals A Feed-Forward Loop In The JAK pathway Mediated By P38 Mapk Signalling.
- A Bayesian Gene Network Reveals Insight Into The JAK-Stat Pathway In Systemic Lupus Erythematosus
- A Bioarchaeological Study Of Trauma At Late Iron Age To Protohistoric Non Ban Jak, Northeast Thailand
- A bipolar clamp mechanism for activation of JAK-family protein tyrosine kinases
- A Case Of Giant Prolactinoma With JAK 2 Positive Mutation
- A case of JAK-2 positive essential thrombocythemia followed by mantle cell lymphoma
- A Cgifnlp Receptor From Crassostrea Gigas And Its Activation Of The Related Genes In Human Jak/Stat Signaling Pathway
- A CK2-dependent mechanism for activation of the JAK-STAT signaling pathway: implications for cancer biology
- A Comment On JAK Inhibitors For Treatment Of Alopecia Areata
- A Common Docking (CD) Domain in Progesterone Receptor-B Links Rapid Signaling Events to Jak/Stat-dependent Gene Expression Required for Breast Cancer …
- A De Novo Transcriptome Analysis Shows That Modulation Of The JAK-Stat Signaling Pathway By Salmonid Alphavirus Subtype 3 Favors Virus Replication In …
- A De Novo Transcriptome Analysis Showsthat Modulation Of The JAK-Stat Signalingpathway By Salmonid Alphavirus Subtype 3Favors Virus Replication In …
- A determinant of Sindbis virus neurovirulence enables efficient disruption of Jak/Stat signaling
- A Distinct Transcriptional Profile In Response To Endothelial Monocyte Activating Polypeptide Ii Is Partially Mediated By JAK-Stat3 In Murine Macrophages
- A Drosophila Model Of Myeloproliferative Neoplasm Reveals A Feed-Forward Loop In The JAK pathway Mediated By P38 Mapk Signalling
- A GEF-to-phospholipase molecular switch caused by phosphatidic acid, Rac and JAK tyrosine kinase that explains leukocyte cell migration
- A Gene Expression Screen For Jak/Stat And Egfr Target Genes During Drosophila Melanogaster Oogenesis
- A Gene Expression Screen In Drosophila Melanogaster Identifies Novel Jak/Stat And Egfr Targets During Oogenesis
- A Genetic Screen Reveals An Unexpected Role For Yorkie Signaling In Jak/Stat-Dependent Hematopoietic Malignancies In Drosophila Melanogaster
- A GMCSF and IL-15 fusokine leads to paradoxical immunosuppression in vivo via asymmetrical Jak/Stat signaling through the IL-15 receptor complex
- A gradient of JAK pathway activity patterns the anterior-posterior axis of the follicular epithelium
- A High-Throughput Screen Indicates Gemcitabine And JAK Inhibitors May Be Useful For Treating Pediatric Aml
- A Hispanolone-Derived Diterpenoid Inhibits M2-Macrophage Polarization In Vitro Via Jak/Stat And Attenuates Chitin Induced Inflammation In Vivo
- A Jak/Stat invasion
- A JAK-Stat Pathway Target Gene Encoding A Single Wap Domain (Swd)-Containing Protein From Litopenaeus Vannamei
- A Janus Kinase From Scylla Paramamosain Activates Jak/Stat Signaling Pathway To Restrain Mud Crab Reovirus
- A Janus Kinase In The Jak/Stat Signaling Pathway From Litopenaeus Vannamei Is Involved In Antiviral Immune Response
- A Kaposi’s sarcoma-associated herpesvirus protein that forms inhibitory complexes with type I interferon receptor subunits, JAK and STAT proteins, and blocks …
- A KSHV protein that forms inhibitory complexes with type I interferon receptor subunits, JAK and STAT proteins and blocks interferon-mediated signal …
- A life among atoms, or how it was all beginning, here and elsewhere; Zivot mezi atomy, aneb JAK to vsechno u nas i jinde zacinalo
- A Mathematical Model of the Jak/Stat1 Signal Transduction Pathway
- A microelectronic DNA chip detects the V617F JAK-2 mutation in myeloproliferative disorders
- A Model System To Treat T-Cell Acute Lymphoblastic Leukemia With JAK Inhibitors
- A mutant form of JAB/SOCS1 augments the cytokine-induced Jak/Stat pathway by accelerating degradation of wild-type JAB/CIS family proteins through the SOCS …
- A new modality for immunosuppression: targeting the Jak/Stat pathway
- A new regulatory switch in a JAK protein kinase
- A new signaling pathway (JAK-Fes-phospholipase D) that is enhanced in highly proliferative breast cancer cells
- A new therapeutical option for chronic inflammation in rheumatology: janus kinases inhibitors (JAK)
- A Novel Ace2 Activator Reduces Monocrotaline-Induced Pulmonary Hypertension By Suppressing The Jak/Stat And Tgf-Β Cascades With Restored Caveolin-1 …
- A Novel Chimeric Antigen Receptor Containing A Jak–Stat Signaling Domain Mediates Superior Antitumor Effects
- A Novel Cyclic Helix B Peptide Inhibits Dendritic Cell Maturation During Amelioration Of Acute Kidney Graft Rejection Through JAK-2/Stat3/Socs1
- A novel functional activator of the Drosophila Jak/Stat pathway, unpaired2, is revealed by an in vivo reporter of pathway activation
- A Novel Germline Mutation In The 3’Untranslated Region Of Calreticulin Gene Induces Jak/Stat Sig
- A novel mode of activating the JAK–STAT signaling pathway
- A novel role for Jak/Stat signaling in cell migration during development and in cancer.
- A Novel Role Of Angiotensin Ii In Epidermal Cell Lineage Determination: Angiotensin Ii Promotes The Differentiation Of Mesenchymal Stem Cells Into Keratinocytes Through The P38 Mapk, Jnk And Jak2 Signalling Pathways
- A novel strategy of protein engineering in dissecting SUMO interactions within the Jak/Stat pathway. Adam Cheng, Clarence Pasion, Xiulin Shen, and Jiayu …
- A novel type II membrane receptor up‐regulated by IFN‐α in fibroblasts functions in cell proliferation through the JAK‐STAT signalling pathway
- A novel type-1 cytokine receptor from fish involved in the Janus kinase/signal transducers and activators of transcription (Jak/Stat) signal pathway
- A Phase 2 Study Of Cpi-0610, A Bromodomain And Extraterminal Domain Inhibitor (Beti), In Combination With Ruxolitinib, In JAK Inhibitor (Jaki) Treatment Naïve …
- A positive autoregulatory loop of JAK-STAT signaling controls the onset of astrogliogenesis
- A Preliminary Study on the Response of Jak/Stat Pathway to Bombyx mori Baculovirus Infection
- A Randomized, Double‐Blind, Placebo‐Controlled, Twelve‐Week, Dose‐Ranging Study Of Decernotinib, An Oral Selective Jak‐3 Inhibitor, As Monotherapy In Patients With …
- A randomized, placebo‐controlled study of the pharmacokinetics, pharmacodynamics, and tolerability of the oral JAK 2 inhibitor fedratinib (SAR 302503) in healthy …
- A receptor-independent, cell-based JAK activation assay for screening for JAK3-specific inhibitors
- A remarkable new thripid (Terebrantia: Thripidae) from JAK trees (Moraceae) in Bangalore (Karnataka), India
- A Retrospective Study Of JAK-2 Mutations, Endogenous Erythroid Colony Formation Assay In Absolute Erythrocytosis Patients In A Tertiary Care Centre, South India
- A Review of Jak/Stat Signal Transduction Pathway and Chinese Medicine in The Treatment of Parkinson’s Disease
- A Review: Phytochemicals Targeting Jak/Stat Signaling And Ido Expression In Cancer
- A road map for those who don’t know JAK-STAT
- A role for the JAK-STAT1 pathway in blocking replication of HSV-1 in dendritic cells and macrophages
- A Schistosoma Japonicum Infection Promotes The Expansion Of Myeloid-Derived Suppressor Cells By Activating The Jak/Stat3 Pathway
- A Sesquiterpenoid From Farfarae Flos Induces Apoptosis Of Mda-Mb-231 Human Breast Cancer Cells Through Inhibition Of Jak–Stat3 Signaling
- A Sesquiterpenoid From The Farfarae Flos Induces Apoptosis Of Mda-Mb-231 Human Breast Cancer Cells Through Inhibition Of JAK-Stat3 Signaling
- A short receptor downregulates Jak/Stat signalling to control the Drosophila cellular immune response
- A Shrimp Gene Encoding A Single Wap Domain (Swd)-Containing Protein Regulated By JAK-Stat And Nf-Κb Pathways
- A simple work flow for biologically inspired model reduction-application to early JAK-STAT signaling
- A small-molecule compound identified through a cell-based screening inhibits Jak/Stat pathway signaling in human cancer cells
- A Study And Development Of Plastic Fiber Furniture: Ruean-Thai JAK-San Group, Sri-Pran, Sawang-Ha, Ang Thong
- A Study of the Precedent of the Société Nationale Industrielle Aerospatiale v. Lee Kui JAK Case
- A study storage stability of value Added products of JAK fruit
- A systematic analysis of Tinman function reveals Eya and JAK-STAT signaling as essential regulators of muscle development
- A Systematic Review And Meta-Analysis Of Infection Risk With Small Molecule JAK Inhibitors In Rheumatoid Arthritis
- A timely intervention-JAK Kelly and solar
- A tumor suppressor activity of Drosophila Polycomb genes mediated by JAK-STAT signaling
- A tumor-suppressive role of the IL-21R/Jak/Stat3 pathway in the germinal center B cell subtype of diffuse large B cell lymphomas.
- A unifying hypothesis for the renin–angiotensin system and hematopoiesis: sticking the pieces together with the JAK-STAT pathway
- A> 50KDa soluble factor from the stroma-derived conditioned media contributes to resistance towards BCR-ABL inhibitors in CML via the JAK-STAT3 pathway
- A2. 26 JAK-Stat Signalling Regulates Pro-Inflammatory Mediators And Fibroblast Invasion In Ra
- A67 Breakdown: The Cellular Contribution To Pulmonary Hypertension: Proliferative, Hyper-Migratory Phenotype And Jak/Stat Activation In Dermal …
- AB0040 Il-29 induces production of il-6 and il-8 in rheumatoid arthritis synovial fibroblasts via Jak/Stat3 and mapk/nf-kb signaling pathways
- Ab0040 JAK Inhibitors–Baricitinib And Tofacitinib–Modulate The In Vitro Inflammatory And Alternative Polarizations Of …
- Ab0091 Hypoxia Induce Slug Expression Via Jak/Stat3 Pathway In Rheumatoid Arthritis Fibroblast-Like Synoviocytes
- Ab0145 The Inhibition Of JAK pathway Was Associated With Reduction Of Autophagy In Synoviocytes From Rheumatoid …
- AB0164 Analysis of JAK-Stat-Socs Signal Pathway MRNA Expression in Ankylosing Spondylitis (AS) Patients with Peripheral Arthritis (PA)
- Ab0188 Effect Of Mir-19A And Mir-21 On The Jak/Stat Signaling Pathway In The Peripheral Blood Mononuclear Cells Of Patients With Systemic Juvenile Idiopathic …
- Ab0435 Real World Data Of A Patient Cohort With Rheumatoid Artritis Treated With Jak/Stat Inhibitors
- Ab0437 Safety Of JAK Inhibitors In Patients With Rheumatoid Arthritis In Conditions Of Daily Clinical Practice
- Ab1319 Efficacy And Safety Of The Treatment With JAK Inhibitors In Patients With Ra. Results Of A Case Series Of Usual …
- Ab1339 Online Cme Improves Adoption Of JAK Inhibitors In Clinical Practice By Rheumatologists
- Aberrant Jak/Stat signaling confers epigenetic silencing of STAT3 targets in gastric cancer by integrated microarray and bioinformatic analysis
- Aberrant Jak/Stat Signaling Orchestrates Global Promoter Methylation And Promotes Tgf-Β Mediated Emt Through Epigenetic Silencing Of Mir-193A In Gastric Cancer
- Aberrant Jak/Stat Signaling Suppresses Tff1 And Tff2 Through Epigenetic Silencing Of Gata6 In Gastric Cancer
- Abl oncogene bypasses normal regulation of Jak/Stat activation
- Abnormal lnterferon-𝛽 Function in Multiple Sclerosis: Evaluation of Four Signaling Proteins of the JAK-STAT Pathway in Mononuclear Celis
- Abnormal Repression Of Shp-1, Shp-2 And Socs-1 Transcription Sustains The Activation Of The Jak/Stat3 Pathway And The Progression Of The Disease In …
- Abrogated leptin-induced cardiac contractile response in ventricular myocytes under spontaneous hypertension: role of Jak/Stat pathway
- Abrogation of IL-6-mediated JAK signalling by the cyclopentenone prostaglandin 15d-PGJ2 in oral squamous carcinoma cells
- Abrogation of IL-6-mediated Jak/Stat signaling by the cyclopentenone prostaglandin 15-Deoxy-Δ12, 14-Prostaglandin J2 in oral squamous carcinoma cells
- Abrogation Of Jak/Stat Pathway In Radiosensitization Of Nk/T Cell Lymphoma
- Absence of JAK-2V617F point mutations in multiple myeloma
- Abstract A23: Gene set enrichment analysis of renal cell carcinoma genome-wide association data identifies the JAK-STAT pathway mediating susceptibility
- Abstract A29: Involvement Of JAK-Stat Signaling In Human Pancreatic Adenocarcinoma Cell Lines And Suitability For Targeted Therapy
- Abstract B035: Enhancing Antitumoral Activity Of Cell-Based Immunotherapies By Modulating The JAK-Stat Axis
- Abstract B087: A Systematic Approach To Jak/Stat Pathway Shut-Down
- Abstract B182: Single cell network profiling (SCNP) by flow cytometry as a tool to measure potency and selectivity of Jak/Stat inhibitors in PBMC and whole blood …
- Abstract B91: Genetic variations in the JAK-STAT pathway are associated with postoperative pulmonary complications after lobectomy in lung cancer patients
- Abstract C78: ATR-FANCD2 dependent JAK-STAT pathway up-regulates Procaspase-8 and Bax in Coralyne-UVA induced cancer cell apoptosis.
- Abstract Ct176: Effect Of Jak/Stat Or Pi3Kδ Plus Pd-1 Inhibition On The Tumor Microenvironment: Biomarker Results From A Phase Ib Study In Patients With Advanced …
- Abstract Ia41: Role Of JAK-Stat Pathway Activation In Mpn Pathogenesis And Therapeutic Response.
- Abstract Lb-013: The Immunomodulatory Effect Of JAK Inhibitors Enhances Metastasis By Impairing Antitumor Immunity In Preclinical Models Of Breast Cancer
- Abstract P1-03-13: Immunohistochemistry Cannot Be Used To Detect Pd-L1/JAK-2 Amplification
- Abstract Pr09: A Novel Chimeric Antigen Receptor Containing JAK-Stat Signaling Domains Mediates Superior Antitumor Effects
- Abstract Tp258: Activation Of Jak/Stat3 Restores Nature Killer Cell Function And Improves Immune Defense After Brain Ischemia
- Abstract W Mp49: Classifying M1/M2 Monocytes By Jak/Stat Activation After Murine Intracerebral Hemorrhage
- Abstract# 1541: Interferons downregulate WT1 through the Jak/Stat pathway.
- Abstract# 1867: HMTV Env protein interaction network overlaps with Jak/Stat signaling
- Abstract# 2186: Macrophage migration inhibitory factor (MIF) plays a role in proliferation and survival of Ewing tumor cells through the activation of Jak/Stat, Src and …
- Abstract# 3717: Identification of a dual JAK-2/BCR-ABL kinase inhibitor for treatment of myeloproliferative disorders
- Abstract# 4375: Sustained Src inhibition results in JAK activation and cancer cell survival via altered SOCS expression
- Abstract# 4428: Interleukin-1\# 946; induced iNOS expression is independent of MAPK and JAK-STAT pathways in human non small cell lung carcinoma A549 cells
- Abstract# 4773: Activation of a novel JAK-Stat inhibitory pathway by a small molecule
- Abstract# LB-127: Jak/Stat signaling in Ewing’s sarcoma
- Abstract# LB-92: Frequent JAK mutations in pediatric acute lymphoblastic leukemia with poor outcome: A new therapeutic target in resistant disease.
- Accurate Quantitation Of JAK 2 V617F Allele Burden By Array‐Based Digital Pcr
- Acid Induces Apoptosis To Inhibit Inflammatory Proliferation Of Il-6-Induced Fibroblast-Like Synoviocytes Through Modulating The Activation Of Jak/Stat And Nf …
- Acid Phenethyl Ester Protects The Brain Against Hexavalent Chromium Toxicity By Enhancing Endogenous Antioxidants And Modulating The Jak/Stat Signaling Pathway
- Acquired Resistance To JAK Inhibitors In Calr-Mutated Myeloproliferative Neoplasms
- Acrp30 inhibits leptin-induced metastasis by downregulating the Jak/Stat3 pathway via AMPK activation in aggressive SPEC-2 endometrial cancer cells
- Acteoside Inhibits Inflammatory Response Via Jak/Stat Signaling Pathway In Osteoarthritic Rats
- Activated JAK-Stat Pathway By Il-6 Mediates Macrophage-Induced Angiotensinogen Augmentation In Renal Proximal Tubular Cells
- Activated JAK-Stat Signaling Cooperates With Hoxa9 And Drives Leukemia Development
- Activated Protein Kinase Kinase 2, A Novel E2-Interacting Protein, Promotes The Growth Of Classical Swine Fever Virus Via Attenuation Of The JAK-Stat Signaling Pathway
- Activating Jak1-S703I Mutation May Predict The Sensitivity Of JAK-Stat Inhibition In Hepatocellular Carcinoma Patient-Derived Xenograft Tumor Models
- Activating Mutations Of The Gp130/Jak/Stat Pathway In Human Diseases.
- Activation and Inhibition of JAK-STAT Signal Transduction by RNA Viruses
- Activation of host tissue trophic factors through JAK-STAT3 signaling: a mechanism of mesenchymal stem cell-mediated cardiac repair
- Activation of Jak/Stat pathway transduces cytoprotective signal in rat acute myocardial infarction
- Activation of Jak/Stat signal pathway predicts poor prognosis of patients with gliomas
- ACTIVATION OF Jak/Stat SIGNAL TRANSDUCTION PATHWAY BY ALENDRONATE: NOVEL MECHANISM OF ACTION?
- Activation Of Jak/Stat Signaling In Megakaryocytes Sustains Myeloproliferation In Vivo
- Activation of Jak/Stat signaling pathway in Drosophila melanogaster S2 cell culture
- Activation of Jak/Stat signaling pathway in S2 Drosophila melanogaster cell culture
- Activation of Jak/Stat signalling in neurons following spinal cord injury in mice
- Activation Of Jak/Stat3 Restores Nk-Cell Function And Improves Immune Defense After Brain Ischemia
- Activation of JAK-STAT and nitric oxide signaling as a mechanism for donor heart dysfunction
- Activation of JAK-STAT pathway is required for platelet-derived growth factor-induced proliferation of pancreatic stellate cells
- Activation of JAK-STAT1 signal transduction pathway in lesional skin and monocytes from patients with systemic lupus erythematosus.
- Activation of JAK-STAT3 signaling pathway in chronic subdural hematoma outer membranes
- Activation Of Mechanisms, Mediated By Dcn1-Hace1-, JAK-Stat-And Nf-Κb-Cascade Regulatory Pathways In In Vitro-And In Vivo …
- Activation of the IL-6/Jak/Stat3 signaling pathway in human middle ear cholesteatoma epithelium
- Activation of the IL-6/Jak/Stat3 signaling pathway via up-regulation of Fra-1 in tumor associated macrophages represents a malignant switch in breast carcinoma …
- Activation of the IL-6R/Jak/Stat pathway is associated with a poor outcome in resected pancreatic ductal adenocarcinoma
- Activation of the Jak/Stat pathway by ceramide in cultured human fibroblasts
- Activation of the Jak/Stat pathway following transient focal cerebral ischemia: signaling through Jak1 and Stat3 in astrocytes
- Activation Of The Jak/Stat Pathway In Behcet’S Disease
- Activation of the Jak/Stat Pathway in Epstein Barr Virus+‐Associated Posttransplant Lymphoproliferative Disease: Role of Interferon‐γ
- Activation of the Jak/Stat pathway in human neutrophils by NDMA
- Activation Of The Jak/Stat Pathway In The Lungs Of COPD Patients
- Activation of the Jak/Stat pathway in vascular smooth muscle by serotonin
- Activation Of The Jak/Stat Signal Pathway May Be Involved In Dna Damage Of A549 Cells Induced By X-Ray
- Activation of the Jak/Stat signal transduction pathway in GH-treated rat osteoblast-like cells in culture
- Activation of the Jak/Stat signalling pathway by leukaemia inhibitory factor stimulates trans-differentiation of human non-endocrine pancreatic cells into insulin …
- Activation of the Jak/Stat-1 signaling pathway by IFN-γ can down-regulate functional expression of the MHC class I-related neonatal Fc receptor for IgG
- Activation Of The Jak/Stat3 And Pi3K/Akt Pathways Are Crucial For Il-6 Trans-Signaling-Mediated Pro-Inflammatory Response In Human Vascular Endothelial …
- JAK-STAT_intracellular20160211-32262-1gtihyh.pdf”>Activation of the JAK–sTAT intracellular pathway in human retinal pigment epithelial cell line ARPe-19
- Activation of the JAK-STAT pathway by olanzapine is necessary for desensitization of serotonin2A receptor-stimulated phospholipase C signaling in rat frontal cortex …
- Activation of the JAK-STAT pathway is necessary for desensitization of 5-HT2A receptor-stimulated phospholipase C signalling by olanzapine, clozapine and MDL …
- Activation Of The JAK-Stat Signaling Pathway After In Vitro Stimulation With Ifnss In Multiple Sclerosis Patients According To The Therapeutic Response To Ifnss
- Activation of the JAK-STAT signaling pathway in the rat basilar artery after subarachnoid hemorrhage
- Activation of the JAK-STAT3 pathway is associated with the growth of colorectal carcinoma cells
- Activation of the JAK-Stat-and MAPK-pathways by oncostatin M is not sufficient to cause growth inhibition of human glioma cells
- Activation of the Ras/Raf/MEK pathway facilitates hepatitis C virus replication via attenuation of the interferon-JAK-STAT pathway
- Activation status of the Jak/Stat3 pathway in mantle cell lymphoma
- Activity Of Jak/Stat And Nf-Κb In Patients With Axial Spondyloarthritis.
- Acute Febrile Neutrophilic Dermatosis Associated With JAK-2 Positive Myeloproliferative Disorder
- Acute myeloid leukemia evolving from JAK 2-positive primary myelofibrosis and concomitant CD5-negative mantle cell lymphoma: A case report and review of the …
- Acute Nitrogen Dioxide (No2) Exposure Enhances Airway Inflammation Via Modulating Th1/Th2 Differentiation And Activating JAK-Stat Pathway
- Adenovirus-mediated tissue factor pathway inhibitor gene transfer induces apoptosis by blocking the phosphorylation of JAK-2/STAT-3 pathway in vascular smooth …
- Adipocyte-specific deficiency of Janus kinase (JAK) 2 in mice impairs lipolysis and increases body weight, and leads to insulin resistance with ageing
- Advances In Anti-Viral Immune Defence: Revealing The Importance Of The Ifn Jak/Stat Pathway
- Advances in genome-wide RNAi cellular screens: a case study using the Drosophila Jak/Stat pathway
- Advances in JAK-STAT Signaling Pathway [J]
- Advances in Study on Jak/Stat3 Signaling Pathway and its Role in Gastrointestinal Diseases
- Advances in the discovery of selective JAK inhibitors
- Adverse Events, Clinical Considerations And Management Recommendations In Rheumatoid Arthritis Patients Treated With JAK Inhibitors
- Aedes Aegypti Molecular Responses To Zika Virus: Modulation Of Infection By The Toll And Jak/Stat Immune Pathways And Virus Host Factors
- Aerobic Exercise Reduces Asthma Phenotype Through Inhibition Of Socs-JAK-Stat Signaling In Airway Epithelium
- Aerobic Exercise Reduces Asthma Phenotype Through Modulation Of Socs-JAK-Stat Signaling
- Ag490 Regulated The Invasion And Metastasis Of Gallbladder Sgc-996 Cells Through Jak/Stat3 Pathway
- Age-Related Remodeling Of The Jak/Stat/Socs Signaling Pathway And Associated Myocardial Changes: From Histological To Molecular Level
- Aggressive Natural Killer-Cell Leukemia Mutational Landscape And Drug Profiling Highlight JAK-Stat Signaling As Therapeutic Target
- AICAR induces astroglial differentiation of neural stem cells via activating the Jak/Stat3 pathway independently of AMP-activated protein kinase
- Aicar, An Ampk Activator, Protects Against Cisplatin-Induced Acute Kidney Injury Through The Jak/Stat/Socs Pathway
- Airway smooth muscle CXCR3 ligand production: regulation by JAK-STAT1 and intracellular Ca2+
- Aldose reductase pathway mediates JAK-STAT signaling: a novel axis in myocardial ischemic injury
- ALL-associated JAK1 mutants activate the Jak/Stat pathway via IL-9Rα homodimers
- Allergen‑Removed Rhus Verniciflua Stokes Suppresses Invasion And Migration Of Pancreatic Cancer Cells Through Downregulation Of The Jak/Stat And Src …
- Allylpyrocatechol Attenuates Collagen-Induced Arthritis Via Attenuation Of Oxidative Stress Secondary To Modulation Of The Mapk, Jak/Stat, And Nrf2/Ho-1 Pathways
- Alpha interferon induces long-lasting refractoriness of JAK-STAT signaling in the mouse liver through induction of USP18/UBP43
- Alterations in Jak/Stat signaling pathway and blood-brain barrier function: Mechanisms underlying worsened outcome following stroke in the aged rat
- Alterations in Janus kinase (JAK)-signal transducers and activators of transcription (STAT) signaling in patients with end-stage dilated cardiomyopathy
- Alternative ways of modulating JAK-STAT pathway: Looking beyond phosphorylation
- Alvin Toffler and Heidi Toffler: War and Anti-War: Making Sense of Today’s Global Chaos (Válka a antiválka. JAK porozumet dnesnímu globálnímu chaosu)
- Amelioration of experimental autoimmune encephalomyelitis by plumbagin through down-regulation of JAK-STAT and NF-κB signaling pathways
- American ginseng inhibits vascular smooth muscle cell proliferation via suppressing Jak/Stat pathway
- Amorfrutin A Inhibits Tnf-Α Induced Jak/Stat Signaling, Cell Survival And Proliferation Of Human Cancer Cells
- An activated Jak/Stat3 pathway and CD45 expression are associated with sensitivity to Hsp90 inhibitors in multiple myeloma
- An Alternatively Transcribed Taz Variant Negatively Regulates Jak‐Stat Signaling
- An Angiogenesis Gene Signature Points To Active Tgf-Beta/JAK Signaling Pathways In A Subset Of Human Pancreatic Ductal Adenocarcinoma Cancer Patients That Are …
- An Autocrine Cytokine/Jak/Stat-Signaling Induces Kynurenine Synthesis In Multidrug Resistant Human Cancer Cells
- An essential role of the JAK-2/STAT-3/cytosolic phospholipase A2 axis in platelet-derived growth factor BB-induced vascular smooth muscle cell motility
- An essential role of the JAK-STAT pathway in ischemic preconditioning
- An evolutionary conserved function of the JAK-STAT pathway in anti-dengue defense
- An extracellular activator of the Drosophila Jak/Stat pathway is a sex-determination signal element
- An Immunoevasive Strategy Through Clinically-Relevant Pan-Cancer Genomic And Transcriptomic Alterations Of JAK-Stat Signaling Components
- An inside job: hacking into Jak/Stat signaling cascades by the intracellular protozoan Toxoplasma gondii
- An insight into JAK‐STAT signalling in dermatology
- AN INSIGHT ON THE INTESTINAL TRANSCRIPTIONAL REGULATORS OF MUCINS MEDIATED BY JAK STAT PATHWAY IN SHIGELLA INFECTION
- An Open-Label Trial Of JAK 1/2 Blockade In Progressive Ifih1-Associated Neuroinflammation
- An Update On JAK Inhibitors
- Analysis Of A Quantitative Mathematical Model Of Bistability In The Cross-Repression System Between Apt And Slbo Within The Jak/Stat Signaling Pathway
- Analysis Of Clinical Significance And Prospective Molecular Mechanism Of Main Elements Of The Jak/Stat Pathway In Hepatocellular Carcinoma
- Analysis Of JAK-Stat Signaling Pathway Genes And Their Micrornas In The Intestinal Mucosa Of Genetically Disparate Chicken Lines Induced With Necrotic Enteritis
- Analysis of RNA-Seq data reveals involvement of Jak/Stat signalling during leg regeneration in the cricket Gryllus bimaculatus
- Analysis Of Spontaneous Postmarket Case Reports Submitted To The Fda Regarding Thromboembolic Adverse Events And JAK Inhibitors
- Analyzing effective models: An example from Jak/Stat5 signaling
- Anan Ben Dawid Jako Archetyp Religijnego Wichrzyciela: JAK Raw Natronaj Gaon Przyczynił Się Do Wykreowania Przywódcy Ananitów Na Ojca Założyciela Karaizmu
- Anan Ben Dawid Jako Islamizujący Heretyk Żydowski: O Tym, JAK Raw Saadia Gaon Stworzył Mit Fundacyjny Karaizmu
- Andreas Blümke, JAK Inwestować W Produkty Strukturyzowane, Wolters Kluwer, Warszawa 2013, Ss. 472.
- Androgen metabolism and Jak/Stat pathway genes and prostate cancer risk
- Andrographolide Inhibits Influenza A Virus-Induced Inflammation In A Murine Model Through Nf-Κb And JAK-Stat Signaling Pathway
- Angiotensin 1-7 Suppresses Angiotensin Ii Mediated Aldosterone Production Via Jak/Stat Signaling Inhibition
- Angiotensin II (ANG II) does not utilize the Janus Kinase 2/Signal Transducers of Activated Transcription (Jak/Stat) pathway in the molecular mechanism of blood …
- Angiotensin II activation of the Jak/Stat pathway in mesangial cells is altered by high glucose
- Angiotensin II blockade prevents hyperglycemia-induced activation of JAK and STAT proteins in diabetic rat kidney glomeruli
- Angiotensin Ii In Atrial Structural Remodeling: The Role Of Ang Ii/Jak/Stat3 Signaling Pathway
- Angiotensin II induces IL-6 expression and the JAK-STAT3 pathway in aortic adventitia of LDL receptor-deficient mice
- Angiotensin II signals mechanical stretch-induced cardiac matrix metalloproteinase expression via JAK-STAT pathway
- Angiotensin II type-1 receptor-Jak/Stat pathway mediates the induction of visfatin in angiotensin II-induced cardiomyocyte hypertrophy
- Angiotensin II-induced leptin secretion in rat neonatal cardiomyocytes is mediated by two different mechanisms involving JAK-STAT and NF-kB activation
- Annemarie Zand Scholten Frans J. Oort University of Amsterdam, Amsterdam, the Netherlands E-mail: S. Jak@ uva. nl
- Annexin A1 released from apoptotic cells acts through formyl peptide receptors to dampen inflammatory monocyte activation via Jak/Stat/SOCS signalling
- Antagonizing Cytokine-Mediated JAK-Stat Signaling By Porcine Reproductive And Respiratory Syndrome Virus
- Antagonizing JAK-Stat Signaling By Porcine Reproductive And Respiratory Syndrome Virus
- Anti‐Angiogenic Activity Of Thienopyridine Derivative Lcb 03‐0110 By Targeting Vegfr‐2 And Jak/Stat 3 Signalling
- Anticancer Activity Of Globularifolin Against Human Adenoid Cystic Carcinoma Cells Is Due To Ros-Mediated Apoptotic Cell Death And Modulation Of The Jak/Stat Signalling Pathway
- Anti-Inflammation Effect Of Epicatechin-Gallate Against Lipopolysaccharide-Induced Acute Lung Injury Via Inhibition Jak/Stat1 Pathway
- Anti-Inflammatory Effect Of Resveratrol Through The Suppression Of Nf-Κb And Jak/Stat Signaling Pathways
- Anti-Inflammatory Effects Of Sanguisorbae Radix Water Extract On The Suppression Of Mast Cell Degranulation And Stat-1/JAK-2 Activation In Bmmcs And …
- Anti-Inflammatory Mechanisms Of Koreanaside A, A Lignan Isolated From The Flower Of Forsythia Koreana, Against Lps-Induced Macrophage Activation And Dss-Induced Colitis Mice: The Crucial Role Of Ap-1, Nf-Κb, And Jak/Stat Signaling
- Anti-Inflammatory Potential Of Pi3Kδ And JAK Inhibitors In Asthma Patients
- Anti-inflammatory roles of retinoic acid in rat brain astrocytes: suppression of interferon-γ-induced Jak/Stat phosphorylation
- JAK-inhibitors-for-the-inflammatory-bowel-disease-treat”>Anti-Integrins, Anti-Interleukin 12/23P40, And JAK Inhibitors For The Inflammatory Bowel Disease Treatment
- Anti-Myeloma Effects Of Icariin Are Mediated Through The Attenuation Of Jak/Stat3-Dependent Signaling Cascade
- Anti-Neuroinflammatory Effect Of Sophoraflavanone G From Sophora Alopecuroides In Lps-Activated Bv2 Microglia By Mapk, Jak/Stat And Nrf2/Ho-1 Signaling …
- Anti-Pd1 Up-Regulates Pd-L1 Expression And Inhibits T-Cell Lymphoma Progression: Possible Involvement Of An Ifn-Γ-Associated JAK-Stat Pathway
- Anti-rheumatic effect of JAK-inhibitors
- Anti-Tgev Miller Strain Infection Effect Of Lactobacillus Plantarum Supernatant Based On The JAK-Stat1 Signaling Pathway
- Antitumor activity of a novel Jak/Stat3 inhibitor, NSC-743380
- Anti-Tumor And Anti-Angiogenic Effects Of Fucoidan On Prostate Cancer: Possible JAK-Stat3 Pathway
- Anzelma z Canterbury quattuor modi volendi lub JAK uniknąć oskarżenia Boga o grzech i zło
- AOPPs inhibits cholesterol efflux by down-regulating ABCA1 expression in a Jak/Stat signaling pathway-dependent manner
- Apigenin As An Effective Anticancer Natural Product: Spotlight On Trail, Wnt/Β‐Catenin, Jak‐Stat Pathways, And Micrornas
- Apoptosis induced by tanshinone IIA and cryptotanshinone is mediated by distinct Jak/Stat3/5 and SHP1/2 signaling in chronic myeloid leukemia K562 cells
- Apoptotic body engulfment by hepatic stellate cells promotes their survival by the Jak/Stat and Akt/NF-κB-dependent pathways
- Arctigenin inhibits lipopolysaccharide-induced iNOS expression in RAW264. 7 cells through suppressing JAK-STAT signal pathway
- Ardipusillosideiinhibits The Growth, Invasion And Epithelial-To-Mesenchymal Transitionof Gastric Cancer Cells Through The Jak/Stat3 Signaling Pathway
- Areca Nut Components Stimulate Adam17, Il-1Α, Pge2 And 8-Isoprostane Production In Oral Keratinocyte: Role Of Reactive Oxygen Species, Egf And JAK …
- Arginine-vasopressin activates the JAK-STAT pathway in vascular smooth muscle cells
- Arsenic trioxide induced Jak/Stat3 pathway inhibition in myeloma cell lines
- Artesunate Obliterates Experimental Hepatocellular Carcinoma In Rats Through Suppression Of Il-6-JAK-Stat Signalling
- Artocarpus Altilis Cg-901 Alters Critical Nodes In The Jh1-Kinase Domain Of Janus Kinase 2 Affecting Upstream Jak/Stat3 Signaling
- Asaronic Acid Attenuates Macrophage Activation Toward M1 Phenotype Through Inhibition Of Nf-Κb Pathway And JAK-Stat Signaling In Glucose-Loaded Murine …
- Asaronic Acid Suppresses Diabetic Macrophage Activation Toward M1 Phenotype Through Inhibition Of Nf-Κb Pathway And JAK-Stat Signaling In Glucose-Loaded …
- Ascochlorin Suppresses Mmp‐2‐Mediated Migration And Invasion By Targeting Fak And Jak‐Stat Signaling Cascades
- Aspirin Promotes Apoptosis And Inhibits Proliferation By Blocking G0/G1 Into S Phase In Rheumatoid Arthritis Fibroblast-Like Synoviocytes Via Downregulation Of Jak/Stat3 And Nf-Κb Signaling Pathway
- Assessment Of Jak/Stat Inhibition As A Therapeutic Target In Primary Biliary Cholangitis (Pbc)
- Association Analyses Of The Jak/Stat Signaling Pathway With The Progression And Prognosis Of Colon Cancer
- Association Analysis Of Polymorphic Gene Variants In The Jak/Stat Signaling Pathway With Aging And Longevity
- Association of genetic polymorphisms of key molecules in Jak/Stat signaling pathway with susceptibility of hepatocellular carcinoma
- Association of growth and invasiveness promoting effect of interleukin 6 and JAK-STAT3 signaling pathway in gallbladder carcinoma cells
- Association of JAK‐STAT pathway related genes with lymphoma risk: results of a European case–control study (EpiLymph)
- Association of PI3K and JAK pathways and Macrophages in Retinal Ganglion Cell Survival After Acute Elevation of Intraocular Pressure in Rats With Different …
- Association of SRC-related kinase Lyn with the interleukin-2 receptor and its role in maintaining constitutive phosphorylation of Jak/Stat in human T-cell leukemia …
- Association Study Of Single Nucleotide Polymorphisms In Jak2 And Stat5B Genes And Their Differential Mrna Expression With Mastitis Susceptibility In Chinese …
- Astaxanthin inhibits Jak/Stat-3 signaling to abrogate cell proliferation, invasion and angiogenesis in a hamster model of oral cancer
- Astragaloside Iv Alleviates Heart Failure By Promoting Angiogenesis Through The JAK-Stat3 Pathway
- Asymmetric localisation of cytokine mRNA is essential for Jak/Stat activation during cell invasiveness
- Asymmetrical Allocation Of Jak1 Mrna During Spermatogonial Stem Cell Division In Xenopus Laevis
- Atiprimod blocks phosphorylation of JAK-STAT and inhibits proliferation of acute myeloid leukemia (AML) cells
- Atm‑Jak‑Pd‑L1 Signaling Pathway Inhibition Decreases Emt And Metastasis Of Androgen‑Independent Prostate Cancer
- ATP-mediated kinome selectivity: the missing link in understanding the contribution of individual JAK kinase isoforms to cellular signaling
- Atps-52A Pre-Clinical Combinatorial Strategy To Target The Jak/Stat And Egfr Pathways In Gbm
- Attenuation of IFN-γ-induced B7-H1 expression by 15-deoxy-delta12, 14-prostaglandin J2 via downregulation of the Jak/Stat/IRF-1 signaling pathway
- Autocrine/paracrine erythropoietin signalling promotes Jak/Stat‐dependent proliferation of human cervical cancer cells
- Autophagy Is Essential For Remote Preconditioning Induced Cardioprotection And May Involve JAK-Stat Pathway For Autophagy Activation
- B57 EXPERIMENTAL MODELS OF PULMONARY HYPERTENSION I: Role Of Jak/Stat Signaling In Pulmonary Arterial Hypertension
- B7-H4 (B7X)–Mediated Cross-Talk Between Glioma-Initiating Cells And Macrophages Via The Il6/Jak/Stat3 Pathway Lead To Poor Prognosis In Glioma Patients
- Baicalein reduces lipopolysaccharide-induced inflammation via suppressing Jak/Stats activation and ROS production
- Basal expression levels of IFNAR and JAK-STAT components are determinants of cell-type-specific differences in cardiac antiviral responses
- Baseline JAK Phosphorylation Profile Of Peripheral Blood Leukocytes, Studied By Whole Blood Phosphospecific Flow Cytometry, Is Associated With 1-Year …
- BCL-2 expression is mainly regulated by Jak/Stat3 pathway in human CD34+ hematopoietic cells
- BCR–ABL activates STAT3 via JAK and MEK pathways in human cells
- BD 750, a benzothiazole derivative, inhibits T cell proliferation by affecting the JAK 3/STAT 5 signalling pathway
- BDNF and Jak/Stat: partners in seizure-induced GABA-A receptor downregulation
- BDNF selectively regulates GABAA receptor transcription by activation of the Jak/Stat pathway
- Bdnf Signaling In Epilepsy: Trkb-Induced Jak/Stat Pathway And Phosphorylation Of Lsf In Neurons
- Berberine Downregulates Cdc6 And Inhibits Proliferation Via Targeting JAK-Stat3 Signaling In Keratinocytes
- Bergapten Prevents Lipopolysaccharide-Induced Inflammation In Raw264. 7 Cells Through Suppressing Jak/Stat Activation And Ros Production And Increases The …
- Bet Bromodomain Inhibition Suppresses Transcriptional Responses To Cytokine‐Jak‐Stat Signaling In A Gene‐Specific Manner In Human Monocytes
- Beyond JAK-2: Potential Targets For Myeloproliferative Neoplasm Therapy
- Beyond JAK-Stat: Novel Therapeutic Targets In Ph-Negative Mpn
- Binding Of A C-Type Lectin’S Coiled-Coil Domain To The Domeless Receptor Directly Activates The Jak/Stat Pathway In The Shrimp Immune Response To Bacterial …
- Bioactive compounds or metabolites from black raspberries modulate T lymphocyte proliferation, myeloid cell differentiation and Jak/Stat signaling
- Biological and clinical significance of the JAK-STAT pathway; lessons from knockout mice
- Biological functions of Jak/Stat signaling pathway in Drosophila
- Biological significance of MAPK, AKT and JAK‐STAT protein activation by various erythropoietic factors in normal human early erythroid cells
- Biology and significance of the Jak/Stat signalling pathways
- Biomarkers In Lung Diseases: From Pathogenesis To Prediction To New Therapies: Ifn-Γ-Induced Jak/Stat, But Not Nf-Κb, Signaling Pathway Is Insensitive To …
- Bisphenol A induces leptin receptor expression, creating more binding sites for leptin, and activates the Jak/Stat, MAPK/ERK and PI3K/Akt signalling pathways in …
- Bj‐2266 Ameliorates Experimental Autoimmune Encephalomyelitis Through Down‐Regulation Of The Jak/Stat Signaling Pathway
- Blockade Of The Il-6/Jak/Stat3 Signaling Pathway Inhibits Pancreatic Tumor Cell Growth In 3D Spheroid Cultures And In Xenograft Models
- Blockage of Jak/Stat signalling attenuates renal ischaemia-reperfusion injury in rats
- Blocking of interferon-induced JAK-Stat signaling by Japanese encephalitis virus NS5 through a protein tyrosine phosphatase-mediated mechanism
- Blocking of the alpha interferon-induced JAK-Stat signaling pathway by Japanese encephalitis virus infection
- Bmx-Arhgap Fusion Protein Maintains The Tumorigenicity Of Gastric Cancer Stem Cells By Activating The Jak/Stat3 Signaling Pathway
- Bone morphogenetic protein 2 and dexamethasone synergistically increase alkaline phosphatase levels through Jak/Stat signaling in C3H10T1/2 cells
- Book Review: Robert B. Cialdini, Steve J. Martin, Noah J. Goldstein, Mała Wielka Zmiana. JAK Skutecznie Wywierać Wpływ [The Small Big. Small Changes That …
- Bortezomib induces apoptosis by interacting with Jak/Stat pathway in K562 leukemic cells
- Brain‐derived neurotrophic factor (BDNF) acts primarily via the Jak/Stat pathway to promote neurite growth in the major pelvic ganglion of the rat: Part 2
- Brain‐derived neurotrophic factor (BDNF) acts primarily via the Jak/Stat pathway to promote neurite growth in the major pelvic ganglion of the rat: Part I
- Brain-Derived Neurotrophic Factor Promotes Nerve Regeneration By Activating The Jak/Stat Pathway In Schwann Cells
- Breast Cancer Induces Tolerogenic State Of Healthy Activated Cd4+ Lymphocytes, Characterized By Reduced Pi3K, Nfκb, JAK-Stat, Notch, And Increased Tgfβpathway …
- Brud I Odraza, Czyli JAK Się Zostaje Etnografem. Część 1. Brud Innego
- Budd-Chiari Syndrome In A Patient With JAK-2 Mutation Without Myeloprolifrative Disorder
- Budd-Chiari Syndrome in a Patient with JAK-2 V617F and Factor V G1691A Mutations
- Bufadienolides overcome trail resistance in breast cancer cells via JAK-stat pathway
- Cadmium blocks receptor-mediated Jak/Stat signaling in neurons by oxidative stress
- Caffeic Acid Inhibits Chronic Uvb‐Induced Cellular Proliferation Through Jak‐Stat 3 Signaling In Mouse Skin
- Calcineurin B In Cd4+ T Cells Prevents Autoimmune Colitis By Negatively Regulating The Jak/Stat Pathway
- Calr Versus Jak2 Mutated Essential Thrombocythaemia – A Report On 141 Patients
- Can IL-6 Exert Atheroprotective Action on Human Macrophages via Activation of ABCA1 Through the JAK-2/Stat3 Pathway?
- Can the protective actions of JAK-STAT in the heart be exploited therapeutically? Parsing the regulation of interleukin-6-type cytokine signaling
- Cancer-associated adipose tissue promotes breast cancer progression by paracrine oncostatin M and Jak/Stat3 signaling
- Cancer-associated fibroblast promotes gastric cancer invasion and epithelial-mesenchymal transition via the IL-6/Jak/Stat3 signaling pathway
- Cancer-Associated Fibroblasts Promote The Chemo-Resistance In Gastric Cancer Through Secreting Il-11 Targeting Jak/Stat3/Bcl2 Pathway
- Canonical And Non-Canonical Aspects Of Jak–Stat Signaling: Lessons From Interferons For Cytokine Responses
- Canonical And Non-Canonical Jak/Stat Transcriptional Targets May Be Involved In Distinct And Overlapping Cellular Processes
- Canonical and non-canonical JAK–STAT signaling
- Canonical JAK-Stat Signaling Is Pivotal For Long-Term Depression At Adult Hippocampal Temporoammonic-Ca1 Synapses
- Cantharidin induces apoptosis of human multiple myeloma cells via inhibition of the Jak/Stat pathway
- Capsazepine Attenuates Jak/Stat3 Signaling Pathway, Proliferation, Survival Of Prostate Carcinoma Du145 Cells Through Induction Of The Protein Tyrosine …
- Capsazepine Inhibits Jak/Stat3 Signaling, Tumor Growth, And Cell Survival In Prostate Cancer
- Cardiac overexpression of EPAC1 in transgenic mice protects heart from lipopolysaccharide-induced cardiac dysfunction and inhibits JAK-STAT pathway
- Cardiac Overexpression Of Epac1 In Transgenic Mice Rescues Lipopolysaccharide-Induced Cardiac Dysfunction And Inhibits JAK-Stat Pathway
- Cardiovascular Safety Of Biologics And JAK Inhibitors In Patients With Rheumatoid Arthritis
- Caveolin-1-deficient mice show accelerated mammary gland development during pregnancy, premature lactation, and hyperactivation of the JAK-2/STAT5a signaling …
- JAK-stat/64/00129338″>CB-29. PHOSPHOPROTEOMIC ANALYSIS OF NOVEL Jak/Stat INHIBITORS IN GLIOMA CELLS
- Cd147 (Emmprin) Controls Malignant Properties Of Breast Cancer Cells By Interdependent Signaling Of Wnt And Jak/Stat Pathways
- Cd274 (Pdl1) And Jak2 Genomic Amplifications In Pulmonary Squamous‐Cell And Adenocarcinoma Patients
- CD45 Can Regulate JAK Activity
- CD45 is a JAK phosphatase and negatively regulates cytokine receptor signalling
- CD45 recruits adapter protein DOK-1 and negatively regulates JAK–STAT signaling in hematopoietic cells
- Cd45-Adc Plus Janus Kinase (Jak) Inhibitors As Conditioning For Mhc-Mismatched Murine Hematopoietic Stem Cell Transplantation Is Associated With Minimal …
- Cell Competition Modifies Adult Stem Cell And Tissue Population Dynamics In A JAK-Stat-Dependent Manner
- Cell Fate In Antiviral Response Arises In The Crosstalk Of Irf, Nf-Κb And Jak/Stat Pathways
- Cells with minimal expression of the Jak/Stat pathway related proteins STAT5a and the prolactin receptor: evidence of an alternate prolactin receptor isoform in …
- Central Nervous System Inflammation: Cytokines and Jak/Stat/SOCS Signal Transduction
- Ceramide Induces Human Hepcidin Gene Transcription Through Jak/Stat3 Pathway
- Cerdulatinib, A Novel Dual Syk/JAK Kinase Inhibitor, Has Broad Anti-Tumor Activity In Both Abc And Gcb Types Of Diffuse Large B Cell Lymphoma
- Černý, Michal. JAK Učit Sám Sebe.
- Change of the Role for Jak/Stat3 in IL-6 Response During Adaptation of Hybridoma Cells to Serum-Free Media
- Changes in synovial tissue JAK-STAT expression in rheumatoid arthritis in response to successful DMARD treatment
- Changes In The Expression Profile Of Jak/Stat Signaling Pathway Genes And Mirnas Regulating Their Expression Under The Adalimumab Therapy
- JAK-stat-expression-myocardium-induced/1904/00005768″>Changes of CT-1 and Jak/Stat Expression in Myocardium Induced by Acute Exercise
- Changes Of Il-21 And Its Mediated Jak/Stat Signaling Pathway In Patients With Immune Thrombocytopenia
- CHAPTER HI: EVOLUTIONARY PERSPECTIVES FOR FUNCTIONAL DIVERGENCE OF JAK PROTEIN KINASE DOMAINS AND TISSUE-SPECIFIC GENES
- Characterisation of a dendritic cell subset in synovial tissue from patients with rheumatoid arthritis which strongly express Jak/Stat transcription factors
- Characterisation of a dendritic cell subset in synovial tissue which strongly expresses Jak/Stat transcription factors from patients with rheumatoid arthritis
- Characterisation of Upd2, a Drosophila Jak/Stat pathway ligand
- Characterization of the expression and activation of the members of the JAK family in medulla, cortex and glomerular mesangial cells (GMC) in PPAR alpha knock-out …
- Characterization of the role of Drosophila Jak/Stat signalling in cellular proliferation
- Characterizing intracellular signaling mechanisms involved in the progression of cardiac hypertrophy and failure: involvement of Jak/Stat and MAPK pathways
- Characterizing The Anti-Apoptotic Dependencies Of T-Cell Prolymphocytic Leukemia Identifies Hdac And Jak/Stat Pathway Inhibitors As Promising Combination …
- Chemical JAK Inhibitors For The Treatment Of Rheumatoid Arthritis
- Chemical Proteomics Reveals Target Selectivity Of Clinical JAK Inhibitors In Human Primary Cells
- Chemokines integrate Jak/Stat and G‐protein pathways during chemotaxis and calcium flux responses
- Chernobyl-how it happened; Czarnobyl-JAK do tego doszlo
- Chicken Il-26 Regulates Immune Responses Through The Jak/Stat And Nf-Κb Signaling Pathways
- Chicken leptin receptor is functional in activating JAK-STATpathway in vitro
- Chikungunya virus nonstructural protein 2 inhibits type I/II interferon-stimulated JAK-STAT signaling
- chinmo is a functional effector of the Jak/Stat pathway that regulates eye development, tumor formation, and stem cell self-renewal in Drosophila
- Chlorogenic Acid And Luteolin Synergistically Inhibit The Proliferation Of Interleukin-1Β-Induced Fibroblast-Like Synoviocytes Through Regulating The Activation Of Nf-Κb And Jak/Stat-Signaling Pathways
- Cholinergic agonists regulate monocyte chemoattractant protein-1 (MCP-1) production by activated endothelial cells: Involvement of the Jak/Stat3 pathway (94.29)
- Chronic Activation Of Jnk Jak/Stat And Oxidative Stress Signalling Causes The Loser Cell Status
- Chronic dexamethasone treatment results in resistance, IL6-independence, and altered Jak/Stat signaling in the 7TD1 murine B cell hybridoma.
- Chronic Inflammation In Chronic Obstructive Pulmonary Disease Induces Growth And Metastasis Of Lung Cancer Cells Via Il-6/Jak/Stat3/Nf-Κb Signaling Pathway
- Chronic Inguinal Lymphadenitis In A Patient With Rheumatoid Arthritis Being Treated With Tofacitinib Remission With Antituberculous Therapy And Discontinuation Of JAK Inhibition
- Chronic Neutrophilic Leukemia With Concurrent CSF3R and SETBP1 Mutations: Single Colony Clonality Studies, In Vitro Sensitivity To JAK Inhibitors and Lack Of …
- Chronic Pain In Inflammatory Arthritis: Mechanisms, Metrology, And Emerging Targets—A Focus On The JAK-Stat Pathway
- Chrysin Inhibits Lipopolysaccharide-Induced Inflammatory Responses Of Macrophages Via JAK-Stats Signaling Pathway
- Cigarette Smoke Induction of Mmp9 in Aortic Vascular Smooth Muscle Cells is Mediated by the Jak/Stat Pathway
- Cigarette Smoke–Induced Mmp2 And Mmp9 Secretion From Aortic Vascular Smooth Cells Is Mediated Via The Jak/Stat Pathway
- Ciliary neurotrophic factor and stress stimuli activate the JAK-STAT pathway in retinal neurons and glia
- Ciliary neurotrophic factor induces glial fibrillary acidic protein in retinal Müller cells through the Jak/Stat signal transduction pathway
- Ciliary neurotrophic factor reverses aberrant mitochondrial bioenergetics through the Jak/Stat pathway in cultured sensory neurons derived from streptozotocin …
- Cilostazol Disrupts Tlr-4, Akt/Gsk-3Β/Creb, And Il-6/JAK-2/Stat-3/Socs-3 Crosstalk In A Rat Model Of Huntington’S Disease
- Cinnamaldehyde And Nitric Oxide Attenuate Advanced Glycation End Products‐Induced The Jak/Stat Signaling In Human Renal Tubular Cells
- Circular Rna Circcdk13 Suppresses Cell Proliferation, Migration And Invasion By Modulating The Jak/Stat And Pi3K/Akt Pathways In Liver Cancer
- Circulating miRNAs as new activators of the JAK-STAT3 pathway
- Cirsimarin, A Flavone Glucoside From The Aerial Part Of Cirsium Japonicum Var. Ussuriense (Regel) Kitam. Ex Ohwi, Suppresses The Jak/Stat And Irf-3 Signaling …
- Clc-3 Deficiency Impairs The Neovascularization Capacity Of Early Endothelial Progenitor Cells By Decreasing Cxcr4/JAK-2 Signalling
- Clinical Activity, Safety And Tolerability Of Asn002, A Dual Jak/Syk Inhibitor, In Patients With Non-Hodgkin Lymphoma (Nhl), Myeolfibrosis (Mf), Chronic Lymphocytic …
- Clinical Efficacy Of Launched JAK Inhibitors In Rheumatoid Arthritis
- Clinical Efficacy Of New JAK Inhibitors Under Development. Just More Of The Same?
- Clinical potential of novel therapeutic targets in breast cancer: CDK4/6, Src, Jak/Stat, PARP, HDAC, and PI3K/AKT/mTOR pathways
- Cloning and expression of Drosophila SOCS36E and its potential regulation by the Jak/Stat pathway
- Cloning and sequence analysis of Jak/Stat pathway related major genes of silkworm (Bombyx mori).
- C-Mannosylation Of Thrombopoietin Receptor (C-Mpl) Regulates Thrombopoietin-Dependent JAK-Stat Signaling
- Cnot2 Facilitates Dengue Virus Infection Via Negatively Modulating Ifn-Independent Non-Canonical Jak/Stat Pathway
- CNTF‐evoked activation of JAK and ERK mediates the functional expression of T‐type Ca2+ channels in chicken nodose neurons
- Co-activation of Jak/Stat and p38 MAPK pathways by type I interferon enhances apoptosis in human basophils
- Coactivation of janus tyrosine kinase (Jak) 1 positively modulates prolactin-Jak2 signaling in breast cancer: recruitment of ERK and signal transducer and activator of …
- Coexistence of JAK-2 V617F mutation and prothrombin G20210A mutation in a female patient with essential thrombocythemia
- Cofilin Mediates Lps-Induced Microglial Cell Activation And Associated Neurotoxicity Through Activation Of Nf-Κb And Jak–Stat Pathway
- Colivelin Rescues Ischemic Neuron And Axons Involving Jak/Stat3 Signaling Pathway
- Color, capsaicin and volatile components of baked Thai green chili (Capsicum annuum Linn. var. JAK Ka Pat)
- Combination Antiretroviral Therapy (Cart) Restores Hiv-1 Infection-Mediated Impairment Of JAK-Stat Signaling Pathway
- Combination Curcumin And (−)-Epigallocatechin-3-Gallate Inhibits Colorectal Carcinoma Microenvironment-Induced Angiogenesis By Jak/Stat3/Il-8 Pathway
- Combination Of Gemcitabine And Erlotinib Inhibits Recurrent Pancreatic Cancer Growth In Mice Via The JAK-Stat Pathway
- Combination Therapy: JAK PI3K/mTOR. A Novel Approach for Cancer Treatment
- Combination treatment for myeloproliferative neoplasms using JAK and pan‐class I PI 3K inhibitors
- Combinatorial Strategies For Glioblastoma Using Brain Tumor-Initiating Cells: Targeting The Jak/Stat And Egfr Pathways
- Combined inhibition of epidermal growth factor receptor and Jak/Stat pathways results in greater growth inhibition in vitro than single agent therapy
- Combined Inhibition Of Jak/Stat And Bcl2 During Ex Vivo Nk Cell Expansion Enriches A Highly Cytotoxic Nk Cell Subset
- Combined inhibition of Notch and Jak/Stat is superior to monotherapies and impairs pancreatic cancer progression
- Combined Multivisceral And Renal Transplant In A Patient With JAK-2 Mutation
- Combined Parental Obesity Augments Single-Parent Obesity Effects On Hypothalamus Inflammation, Leptin Signaling (Jak/Stat), Hyperphagia, And Obesity In The Adult …
- Combined silencing of Ras and Jak/Stat inhibitors results in constitutive activation of Ras and Jak/Stat pathways in human hepatocellular carcinoma
- Combined suppression of CASP2 and CASP6 protects retinal ganglion cells from apoptosis and promotes axon regeneration through CNTF-mediated Jak/Stat …
- Comparable potency of IFNα2 and IFNβ on immediate Jak/Stat activation but differential down-regulation of IFNAR2
- Comparative analysis of the Jak/Stat signaling through erythropoietin receptor and thrombopoietin receptor using a systems approach
- Competitiveness for the niche and mutual dependence of the germline and somatic stem cells in the Drosophila testis are regulated by the Jak/Stat signaling
- Complete Genomic Organization and Promoter Analysis of the Round-Spotted Pufferfish JAK1, JAK2, JAK3, and TYK2 Genes
- Complex interactions between the components of the PI3K/AKT/mTOR pathway, and with components of MAPK, Jak/Stat and Notch-1 pathways, indicate their …
- Complex systems biology approach to understanding coordination of JAK-STAT signaling
- Complications Related To Varicella Zoster Virus Infection In Patients With Inflammatory Bowel Disease In The Pre-JAK Inhibitors Era: A Prospective Study
- Comprehensive Assessment Of The Association Between Genes On JAK-Stat Pathway (Ifih1, Tyk2, Il-10) And Systemic Lupus Erythematosus: A Meta-Analysis
- Comprehensive review of JAK inhibitors in myeloproliferative neoplasms
- Computational and mathematical models of the JAK-STAT signal transduction pathway
- Concanavalin-A triggers inflammatory response through Jak/Stat3 signalling and modulates MT1-MMP regulation of COX-2 in mesenchymal stromal cells
- Concomitant activation of the Jak/Stat, PI3K/AKT, and ERK signaling is involved in leptin-mediated promotion of invasion and migration of hepatocellular carcinoma …
- Concomitant activation of the Jak/Stat3 and ERK1/2 signaling is involved in leptin-mediated proliferation of renal cell carcinoma Caki-2 cells
- Concomitant requirement for Notch and Jak/Stat signaling during neuro-epithelial differentiation in the Drosophila optic lobe
- Consequences of ectopic Jak/Stat pathway activation in the Drosophila male germline
- Conservation of Jak/Stat signaling in vertebrates
- Conserved regulation of the Jak/Stat pathway by the endosomal protein asrij maintains stem cell potency
- Constitutional activation of IL-6-mediated Jak/Stat pathway through hypermethylation of SOCS-1 in human gastric cancer cell line
- Constitutive activation of Jak/Stat proteins in Epstein-Barr virus-infected B-cell lines from patients with posttransplant lymphoproliferative disorder1
- Constitutive activation of JAK–STAT3 signaling by BRCA1 in human prostate cancer cells
- Constitutive activation of Stat3 by the Src and JAK tyrosine kinases participates in growth regulation of human breast carcinoma cells
- Constitutive and induced activation of Jak/Stat pathway in leukemogenic and asymptomatic human T-cell lymphoptropic virus type 1 (HTLV-1) transformed rabbit cell …
- Constitutive expression of a complement-like protein in toll and JAK gain-of-function mutants of Drosophila
- Constitutively active Gα16 stimulates STAT3 via a c-Src/JAK-and ERK-dependent mechanism
- Contributions of the Raf/MEK/ERK, PI3K/PTEN/Akt/mTOR and Jak/Stat pathways to leukemia
- Control mechanism of Jak/Stat signal transduction pathway
- Control Of Growth And Patterning: A Novel Role For Jak/Stat In Regulation Morphogen Production And Signaling
- Control of stem cell self-renewal in Drosophila spermatogenesis by JAK-STAT signaling
- Convergence of protein kinase C and JAK-STAT signaling on transcription factor GATA-4
- Cooperation of Jak/Stat and Notch signaling in the Drosophila foregut
- Cooperative regulation of the induction of the novel antibacterial Listericin by peptidoglycan recognition protein LE and the JAK-STAT pathway
- Coordinate regulation of stem cell competition by Slit-Robo and JAK-STAT signaling in the Drosophila testis
- Coordinated Regulation Of Cap-Dependent Translation And Microrna Function By Convergent Signaling Through The Pi3K/Akt/Mtor And Jak/Stat/Pim Signaling …
- Coronary effluent from a preconditioned heart activates the JAK-STAT pathway and induces cardioprotection in a donor heart
- Correction: Down-Regulation Of Tlr And Jak/Stat Pathway Genes Is Associated With Diffuse Cutaneous Leishmaniasis: A Gene Expression Analysis In Nk Cells …
- Correction: Inhibition Of The Jak/Stat Signaling Pathway In Regulatory T Cells Reveals A Very Dynamic Regulation Of Foxp3 Expression
- Correction: Suppression Of Usp18 Potentiates The Anti-Hbv Activity Of Interferon Alpha In Hepg2. 2.15 Cells Via Jak/Stat Signaling
- Correction: The Synthetic α-Bromo-2′, 3, 4, 4′-Tetramethoxychalcone (α-Br-TMC) Inhibits the Jak/Stat Signaling Pathway
- Correlation analysis of JAK-STAT pathway components on prognosis of patients with prostate cancer
- Correlation Of Egfr Del 19 With Fn14/Jak/Stat Signaling Molecules In Non-Small Cell Lung Cancer
- Correlation Of Polymorphisms Of JAK And Stat With Gefitinib-Induced Hepatotoxicity In Patients With Non-Small Cell Lung Cancer.
- Correlative Study On The JAK-Stat/Psmβ3 Signal Transduction Pathway In Asthenozoospermia
- Corrigendum To “Linc01116 Targets Mir-520A-3P And Affects Il6R To Promote The Proliferation And Migration Of Osteosarcoma Cells Through The JAK-Stat Signaling Pathway” [Biomed. Pharmacother. 107 (2018) 270-282].
- Corrigendum To “Apoptosis Induced By Tanshinone Iia And Cryptotanshinone Is Mediated By Distinct Jak/Stat3/5 And Shp1/2 Signaling In Chronic Myeloid …
- Corrigendum To “Jak/Stat Signaling Prevents Excessive Apoptosis To Ensure Maintenance Of The Interfollicular Stalk Critical For Drosophila Oogenesis”[Dev. Biol. 438 …
- Corrigendum To “The Long Noncoding Rna Meg3 And Its Target Mir-147 Regulate Jak/Stat Pathway In Advanced Chronic Myeloid Leukemia”[Ebiomedicine 35 (2018) …
- Corrigendum: Inhibition Of JAK-Stat Signaling Stimulates Adult Satellite Cell Function
- Cotargeting The Jak/Stat Signaling Pathway And Histone Deacetylase By Ruxolitinib And Vorinostat Elicits Synergistic Effects Against Myeloproliferative Neoplasms
- Cox-1 Derived Thromboxane A2 Plays An Essential Role In Early B Cell Development Via Regulation Of Jak/Stat5 Signaling In Mice (Lym7P. 619)
- COX-2 inhibitors modulate IL-12 signaling through JAK-STAT pathway leading to Th1 response in experimental allergic encephalomyelitis
- CP690, 550 inhibits oncostatin M-induced Jak/Stat signaling pathway in rheumatoid synoviocytes
- Crizotinib Induces Apoptosis Of Lung Cancer Cells Through JAK-Stat Pathway
- Crohn’S Disease Mucosal Transcriptomes Highlight Jak/Stat Pathway Involvement In Postoperative Recurrence
- Cross Talk Between Tgf-Β And JAK Expressions And Nepherotoxicity Induced By Tetrachloromethane: Role Of Phytotherapy
- Cross-Reactivity Of Antibodies Against Interferon Beta In Multiple Sclerosis Patients And Interference Of The JAK-Stat Signaling Pathway
- Cross-regulation of JAK and Src kinases
- Cross-Regulation of JAK-STAT Signaling: Implications for Approaches to Combat Chronic Inflammatory Diseases and Cancers
- Crosstalk among Jak‐STAT, Toll‐like receptor, and ITAM‐dependent pathways in macrophage activation
- Cross‐talk between calcineurin/NFAT and Jak/Stat signalling induces cardioprotective αB‐crystallin gene expression in response to hypertrophic stimuli
- Crosstalk with the JAK-STAT pathway in inflammation
- Cross-talking between Jak/Stat3 and MAPK/ERK signaling transaction pathways on invasion and metastasis of the human breast cancer cells.
- Crystallographic Instrumentation. By LA Aslanov, GV Fetisov and JAK Howard. IUCr Monographs on Crystallography, 7. Oxford: Oxford University Press/International …
- C-Terminal Hsp90 Inhibitor, L80, Targets Cancer Stem Cell (Csc)-Like Property And Suppresses Metastasis Via Jak/Stat3 Inactivation In Triple-Negative Breast Cancer
- Cucurbitacin B induces apoptosis by inhibition of the Jak/Stat pathway and potentiates antiproliferative effects of gemcitabine on pancreatic cancer cells
- Cucurbitacin E Reduces Obesity And Related Metabolic Dysfunction In Mice By Targeting JAK-Stat5 Signaling Pathway
- Curculigoside Exerts Significant Anti‑Arthritic Effects In Vivo And In Vitro Via Regulation Of The Jak/Stat/Nf‑Κb Signaling Pathway
- Curcumin Augments The Cardioprotective Effect Of Metformin In An Experimental Model Of Type I Diabetes Mellitus; Impact Of Nrf2/Ho-1 And Jak/Stat Pathways
- Curcumin induces growth-arrest and apoptosis in association with the inhibition of constitutively active JAK–STAT pathway in T cell leukemia
- Curcumin Inhibits Proliferation, Migration, Invasion And Promotes Apoptosis Of Retinoblastoma Cell Lines Through Modulation Of Mir-99A And Jak/Stat …
- Curcumin Regulates Anti-Inflammatory Responses By Jak/Stat/Socs Signaling Pathway In Bv-2 Microglial Cells
- Curcumin Suppressed Activation Of Dendritic Cells Via Jak/Stat/Socs Signal In Mice With Experimental Colitis
- Curcumin Suppresses Invasiveness And Vasculogenic Mimicry Of Squamous Cell Carcinoma Of The Larynx Through The Inhibition Of JAK-2/Stat-3 Signaling …
- Curcumin suppresses the induction of indoleamine 2, 3-dioxygenase by blocking the JAK-PKC-δ-STAT1 signalling pathway in IFN-γ-stimulated murine dendritic …
- Current perspectives on the Jak/Stat signaling pathway and its activating factors in liver fibrosis [J]
- Current Treatment Algorithm For The Management Of Patients With Myelofibrosis, JAK Inhibitors, And Beyond
- Cuzd1 Is A Critical Mediator Of The Jak/Stat5 Signaling Pathway That Controls Mammary Gland Development During Pregnancy
- Cxcl6 Promotes Renal Interstitial Fibrosis In Diabetic Nephropathy By Activating Jak/Stat3 Signaling Pathway
- Cxcl8 Promotes Glioma Progression By Activating The Jak/Stat1/Hif-1Α/Snail Signaling Axis
- Cyclin D-Cdk4 and cyclin E-Cdk2 regulate the Jak/Stat signal transduction pathway in Drosophila
- Cytokine Exocytosis And Jak/Stat Activation In The Drosophila Ovary Requires The Vesicle Trafficking Regulator Α-Snap
- Cytokine G-protein signaling crosstalk in cardiomyocytes: Attentuation of JAK-STAT activation by endothelin-1
- Cytokine inhibition of JAK-STAT signaling: a new mechanism of growth hormone resistance
- Cytokine Production In Myelofibrosis Exhibits Differential Responsiveness To JAK-Stat, Map Kinase, And Nfκb Signaling
- Cytokine production through PKC/p38 signaling pathways, not through Jak/Stat1 pathway, in mast cells stimulated with IFNγ
- Cytokine Profile Of Human Abdominal Aortic Aneurysm: Involvement Of Jak/Stat Pathway
- Cytokine receptor signaling through the Jak–Stat–Socs pathway in disease
- Cytokine receptor-like factor 1 (CRLF1) protects against 6-hydroxydopamine toxicity independent of the gp130/JAK signaling pathway
- Cytokine receptors and JAK-STAT signaling
- Cytokine signaling in 2002: new surprises in the Jak/Stat pathway
- Cytokine signaling through the Jak/Stat pathway is required for long-term memory in Drosophila
- Cytokine/Jak/Stat signaling mediates regeneration and homeostasis in the Drosophila midgut
- Cytokine-activated JAK-2 is involved in inducible nitric oxide synthase expression independent from NF-κB activation in vascular smooth muscle cells
- Cytokine-activated JAK-STAT signaling in the mouse immune system
- Cytokine‐Dependent Activation Of Jak‐Stat Pathway In Saccharomyces Cerevisiae
- Cytokine-mediated inflammation, tumorigenesis, and disease-associated Jak/Stat/SOCS signaling circuits in the CNS
- Cytokines And Hepatocellular Carcinoma: Potential Progression Markers And Cell Typespecific Modulators Of The Mirnome (Interleukin-6 And Jak/Stat Activating Cytokines)
- Cytosolic phospholipase A2 is an effector of Jak/Stat signaling and is involved in platelet-derived growth factor BB-induced growth in vascular smooth muscle cells
- Cytotoxicity Of T-2 And Modified T-2 Toxins: Induction Of Jak/Stat Pathway In Raw264. 7 Cells By Hepatopancreas And Muscle Extracts Of Shrimp Fed With T-2 Toxin
- Czterdzieści Lat Minęło, JAK Jeden Dzień… Krótki Zarys Historii Mainzer Polonicum
- D21 Asthma Treatment: Glucocorticoids, Biologicals And Beyond: Aerobic Exercise Reduces Asthma Phenotype Through Modulation Of Socs-JAK …
- D21 Asthma Treatment: Glucocorticoids, Biologicals And Beyond: Pre-Clinical Evaluation Of A Potent Janus Kinase (Jak) Inhibitor Designed For …
- Daily genetic profiling indicates Jak/Stat signaling promotes early hepatic stellate cell transdifferentiation
- Dampening of IFN-γ-inducible gene expression in human choriocarcinoma cells is due to phosphatase-mediated inhibition of the Jak/Stat-1 pathway
- Daphnetin Reduces Endotoxin Lethality In Mice And Decreases Lps-Induced Inflammation In Raw264. 7 Cells Via Suppressing Jak/Stats Activation And Ros …
- Dark Selection For Jak/Stat-Inhibitor Resistance In Chronic Myelomonocytic Leukemia
- Dataset On Characterization Of Recombinant Interleukin-23Α, Il-12P40 And Il-23 Complex Protein, Which Activates JAK-Stat Signaling Pathway In Chicken Cell …
- Death of multiple myeloma cells induced by cAMP-signaling involves downregulation of Mcl-1 via the Jak/Stat pathway
- Debio 0617B Inhibits Growth Of Stat3-Driven Solid Tumors Through Combined Inhibition Of Jak, Src, And Class Iii/V Receptor Tyrosine Kinases
- Decreased Nk Cell-Mediated Anti-Tumor Immunity Consequent To JAK pathway Inhibition Enhances Metastasis In Preclinical Models Of Breast Cancer.
- Defective JAK-Stat activation in hepatoma cells is associated with hepatitis C viral IFN-α resistance
- Defective Jak–Stat activation in renal cell carcinoma is associated with interferon‐α resistance
- Defective JAK-Stat Pathway Signaling Contributes To Autoimmune Diseases
- Defective Jak‐STAT signal transduction pathway in melanoma cells resistant to growth inhibition by interferon‐α
- Defective Signaling In The JAK-Stat Pathway Tracks With Chronic Inflammation And Cardiovascular Risk In Aging Humans
- Defects in Jak–STAT-mediated cytokine signals cause hyper-IgE syndrome: lessons from a primary immunodeficiency
- Defining the role of the JAK-STAT pathway in head and neck and thoracic malignancies: implications for future therapeutic approaches
- Degradation Of Histone Deacetylase 4 Via The Tlr 4/Jak/Stat 1 Signaling Pathway Promotes The Acetylation Of High Mobility Group Box 1 (Hmgb 1) In …
- Dehydrocostus Lactone Suppresses Proliferation Of Human Chronic Myeloid Leukemia Cells Through Bcr/Abl‐Jak/Stat Signaling Pathways
- Deletion of the SOCS box of suppressor of cytokine signaling 3 (SOCS3) in embryonic stem cells reveals SOCS box-dependent regulation of JAK but not STAT …
- Delivery Of Tapasin-Modified Ctl Epitope Peptide Via Cytoplasmic Transduction Peptide Induces Ctls By Jak/Stat Signaling Pathway In Vivo
- Dentatin Exerts Anticancer Effects On Human Colon Cancer Cell Lines Via Cell Cycle Arrest, Autophagy, Inhibition Of Cell Migration And Jak/Stat Signalling Pathway …
- Deregulated Jak/Stat Signalling In Lymphomagenesis, And Its Implications For The Development Of New Targeted Therapies
- De-regulation of JNK and Jak/Stat signaling in ESCRT-II mutant tissues cooperatively contributes to neoplastic tumorigenesis
- Derisking Development By A Cocrystallization Screen Of A Novel Selective Inhaled JAK-Stat Inhibitor
- Design And Development Of Home Decoration From The Plastic: Ruean Thai JAK-San Group, Sripran, Sawang-Ha, Ang Thong
- Design And Synthesis Of Ligand Efficient Dual Inhibitors Of Janus Kinase (Jak) And Histone Deacetylase (Hdac) Based On Ruxolitinib And Vorinostat
- Design And Synthesis Of Triple Inhibitors Of Janus Kinase (Jak), Histone Deacetylase (Hdac) And Heat Shock Protein 90 (Hsp90)
- Design, Synthesis And Anti-Inflammatory Evaluation Of Novel Pyrrolo [2, 3-D] Pyrimidin Derivatives As Potent JAK Inhibitors
- Designing RNAi screens to identify Jak/Stat pathway components
- Detecting Plasmodium-derived MIF’s effect on JAK-STAT signal pathway in macrophage of mouse by real-time PCR chip.
- Detection Of Mutations In Jak2 Exons 12–15 By Sanger Sequencing
- Detection Of Serum Tumor Marker Contents Of Liver Cancer Patients And Its Correlation With JAK-Stat Pathway In Tumor Tissue
- Determination Of Egfr Signaling Output By Opposing Gradients Of Bmp And Jak/Stat Activity
- Determination of protein turnover rates in the Jak/Stat pathway using a radioactive pulse-chase approach
- Determining The Prognostic Significance Of Pi3K/Akt/Mtor And Jak/Stat5 Signaling Pathways In Pediatric Acute Lymphoblastic Leukemia Using Single-Cell Analysis
- Developing A New Project: The Impact Of Social Change On Health At The Late Iron Age Site Of Non Ban JAK In Northeast Thailand
- Development and Characterization of a JAK-2− specific Antibody Suitable for Immunohistochemical Investigative Studies
- Development Of A Human Whole Blood Screening Platform To Monitor Jak/Stat Signaling Using High-Throughput Flow Cytometry
- Development of a novel azaspirane that targets the JAK-STAT pathway in hepatocellular carcinoma in vitro and in vivo
- Development of fresh cut vegetables (elabatu, banana blossom, immature JAK fruit)
- Dexamethasone attenuates bleomycin-induced lung fibrosis in mice through TGF-β, Smad3 and JAK-STAT pathway
- Dexmedetomidine Alleviates Neuropathic Pain By Regulating Jak/Stat Pathway In Rats
- Dexmedetomidine Pretreatment Reduces Myocardial Ischemia And Reperfusion Injury In Rats By Altering Jak/Stat And Pi3K/Akt Levels
- Diabetes impairs an interleukin-1β-dependent pathway that enhances neurite outgrowth through Jak/Stat3 modulation of mitochondrial bioenergetics in …
- Diagnosis And Treatment Of Rheumatoid Arthritis: Toward The Best Practice. Best Practice With JAK Inhibitors.
- Diagnosis Of Del (5Q) Mds, 14 Years After JAK-2 Positive Pv Appearance: Complete Remission Of Both Diseases With Lenalidomide Monotherapy
- Diagnostic value of JAK2 V617F somatic mutation for myeloproliferative cancer in 49 488 individuals from the general population
- Dibutyltin Depressed Immune Functions Via Nf‐Κb, And Jak/Stat Signaling Pathways In Zebrafish (Danio Rerio)
- Dietary Extra Virgin Olive Oil Attenuates Kidney Injury In Pristane-Induced Sle Model Via Activation Of Ho-1/Nrf-2 Antioxidant Pathway And Suppression Of Jak/Stat, Nf-Κb And Mapk Activation
- Dietary flavonoids differentially reduce oxidized LDL-induced apoptosis in human endothelial cells: role of MAPK-and Jak/Stat-signaling
- Dietary Oleuropein And Its New Acyl-Derivate Attenuate Murine Lupus Nephritis Through Ho-1/Nrf2 Activation And Suppressing Jak/Stat, Nf-Κb, Mapk And Nlrp3 …
- Dietary Quercetin Potentiates The Antiproliferative Effect Of Interferon-Α In Hepatocellular Carcinoma Cells Through Activation Of Jak/Stat Pathway Signaling By …
- Differences In Gene Expression And Alterations In Cell Cycle Of Acute Myeloid Leukemia Cell Lines After Treatment With JAK Inhibitors
- Different density matrine to liver cancer cell multiplication and JAK-STAT signal transduction influence [J]
- Differential activation of JAK enzymes in rheumatoid arthritis and autoimmune disorders by pro-inflammatory cytokines: potential drug targets
- Differential activities of the Drosophila Jak/Stat pathway ligands Upd, Upd2 and Upd3
- Differential Antigen Expression And Aberrant Signaling Via Pi3/Akt, Map/Erk, Jak/Stat, And Wnt/Β Catenin Pathways In Lin−/Cd38−/Cd34+ Cells In Acute Myeloid …
- Differential effects of interleukin-13 and interleukin-6 on Jak/Stat signaling and cell viability in pancreatic β-cells
- Differential Expression Analysis Of Jak/Stat Pathway Related Genes In Breast Cancer
- Differential Expression Of Il-6/Gp130 Cytokines, JAK-Stat Signaling And Neuroprotection After Müller Cell Ablation In A Transgenic Mouse Model
- Differential regulation of proliferation and differentiation in neural precursor cells by the JAK pathway
- Differential role of JAK-STAT signaling in retinal degenerations
- Differential sensitivity to JAK inhibitory drugs by isogenic human erythroblasts and hematopoietic progenitors generated from patient‐specific induced pluripotent stem …
- Differentially Expressed JAK-Stat Signaling Pathway Genes And Target Micrornas In The Spleen Of Necrotic Enteritis-Afflicted Chicken Lines
- Diminished Jak/Stat Signaling Causes Early-Onset Aging Defects In Stem Cell Cytokinesis
- Dipping into Incyte’s JAK-pot
- Dipyrithione inhibits IFN-γ-induced Jak/Stat1 signaling pathway activation and IP-10/CXCL10 expression in RAW264. 7 cells
- Disclosing Jak/Stat links to cell adhesion and cell polarity
- Discovery and development of Janus Kinase (JAK) inhibitors for inflammatory diseases: Miniperspective
- Discovery Of 3, 6-Dihydroimidazo [4, 5-D] Pyrrolo [2, 3-B] Pyridin-2 (1H)-One Derivatives As Novel JAK Inhibitors
- Discovery of 5-Chloro-N2-[(1S)-1-(5-fluoropyrimidin-2-yl)ethyl]-N4-(5-methyl-1H-pyrazol-3-yl)pyrimidine-2,4-diamine (AZD1480) as a Novel Inhibitor of the JAK …
- Discovery Of Jak/Stat Signalling Pathway Single Nucleotide Polymorphisms Associating With Primary Arterial …
- Discovery Of Novel Janus Kinase (Jak) And Histone Deacetylase (Hdac) Dual Inhibitors For The Treatment Of Hematological Malignancies
- Discovery of pyrrolo [1, 2-b] pyridazine-3-carboxamides as Janus kinase (JAK) inhibitors
- Discovery Of Subtype Selective Janus Kinase (Jak) Inhibitors By Structure-Based Virtual Screening
- Discovery Of Tricyclic Dipyrrolopyridine Derivatives As Novel JAK Inhibitors
- Disorders Of The Jak/Stat Pathway In T Cell Lymphoma Pathogenesis: Implications For Immunotherapy
- DISRUPTION OF THE IL-10 Jak/Stat SIGNALING PATHWAY INHIBITS THE GROWTH OF EBV TRANSFORMED B CELL LYMPHOMAS DERIVED FROM PTLD …
- Dissecting specificity in the Janus kinases: the structures of JAK-specific inhibitors complexed to the JAK1 and JAK2 protein tyrosine kinase domains
- Dissection Of The Effects Of JAK And Btk Inhibitors On The Functionality Of Healthy And Malignant Lymphocytes
- Dissection Of The Effects Of JAK And Btk Inhibitors On The Functionality Of Healthy And Malignant Lymphocytes: Pb1877
- Distinct Components of Jak/Stat Signaling Pathway Mediate the Regulation of Systemic and Tissue Localized Renin-Angiotensin System
- Distinct patterns of DNA damage response and apoptosis correlate with Jak/Stat and PI3kinase response profiles in human acute myelogenous leukemia
- Distinct Transcriptional Profile Activated By Scye1 Through JAK-Mediated Stat3 In Partially Activated Macrophages
- Diverse tumor pathology due to distinctive patterns of Jak/Stat pathway activation caused by different Drosophila polyhomeotic alleles
- Djc Suppresses Advanced Glycation End Products-Induced JAK-Stat Signaling And Ros In Mesangial Cells
- DNA damage in mammalian neural stem cells leads to astrocytic differentiation mediated by BMP2 signaling through JAK-STAT
- DNA methylation controls the timing of astrogliogenesis through regulation of JAK-STAT signaling
- Dna Methylation-Based Classification Highlights The Role Of The JAK-Stat Pathway In Acute Myeloid Leukemia
- Do We Know Jack” About Jak? A Closer Look At Jak/Stat Signaling Pathway
- Does immune stimulation or antioxidant therapy reduce MNU-induced placental damage via activation of JAK-STAT and NFκB signaling pathways?
- Down-modulation of type 1 interferon responses by receptor cross-competition for a shared JAK kinase
- Down-Regulated Microrna-183 Mediates The Jak/Stat Signaling Pathway To Attenuate Hippocampal Neuron Injury In Epilepsy Rats By Targeting Foxp1
- Downregulation Of Leptin Inhibits Growth And Induces Apoptosis Of Lung Cancer Cells Via The Notch And Jak/Stat3 Signaling Pathways
- Down‐Regulation Of Microrna‐9 Leads To Activation Of Il‐6/Jak/Stat3 Pathway Through Directly Targeting Il‐6 In Hela Cell
- Down-regulation of SHP1 and up-regulation of negative regulators of Jak/Stat signaling in HTLV-1 transformed cell lines and freshly transformed human peripheral …
- Downregulation Of Tfr1 Promotes Progression Of Colorectal Cancer Via The Jak/Stat Pathway
- Down-Regulation Of Tlr And Jak/Stat Pathway Genes Is Associated With Diffuse Cutaneous Leishmaniasis: A Gene Expression Analysis In Nk Cells From …
- Dramatic Resolution Of Hlh After Treatment With The JAK 1/2 Inhibitor, Ruxolitinib
- Drosophila follicle cells are patterned by multiple levels of Notch signaling and antagonism between the Notch and Jak/Stat pathways
- Drosophila glypicans Dally and Dally-like are essential regulators for Jak/Stat signaling and Unpaired distribution in eye development
- Drosophila Jak/Stat pathway reveals distinct initiation and reinforcement steps in early transcription of Sxl
- Drosophila Jak/Stat Signaling: Regulation And Relevance In Human Cancer And Metastasis
- Drosophila linker histone H1 coordinates STAT-dependent organization of heterochromatin and suppresses tumorigenesis caused by hyperactive JAK-STAT …
- Drosophila optic lobe neuroblasts triggered by a wave of proneural gene expression that is negatively regulated by Jak/Stat
- Drosophila RalA is essential for the maintenance of Jak/Stat signalling in ovarian follicles
- Drosophila SOCS36E negatively regulates Jak/Stat pathway signaling via two separable mechanisms
- Drug Discovery Approaches Targeting the Jak/Stat Pathway
- Drug Sensitivity Profiling Identifies Potential Therapies For Lymphoproliferative Disorders With Overactive Jak/Stat3 Signaling
- Drugs Targeting The Jak/Stat Pathway For The Treatment Of Immune-Mediated Inflammatory Skin Diseases: Protocol For A Scoping Review
- Dual mechanism for the impairment of IL-7 responses in HIV infection: decreased IL-7 binding and abnormal activation of the Jak/Stat5 pathway
- Dual role of the Jak1 FERM and kinase domains in cytokine receptor binding and in stimulation-dependent JAK activation
- During Drosophila Disc Regeneration, Jak/Stat Coordinates Cell Proliferation With Dilp8-Mediated Developmental Delay
- Dusp22-Rearranged Anaplastic Lymphomas Are Characterized By Specific Morphological Features And A Lack Of Cytotoxic And Jak/Stat Surrogate Markers
- Dynamics and non-canonical aspects of Jak/Stat signalling
- Dynamics Of Jak2 V617F Allele Burden Of Cd34+ Haematopoietic Progenitor Cells In Patients Treated With Ruxolitinib
- Dysregulated Il-6/Gp130/JAK Signaling In Calreticulin Mutated Myeloproliferative Neoplasms (Mpn)
- Dysregulated JAK-Stat and Wnt signaling pathways in breast tumor microenviroment.
- Dysregulation Of Epithelial Jak/Stat-Signaling Leads To Malformation Of The Fruit Fly’S Airways
- Dysregulation of JAK-STAT pathway in hematological malignancies and JAK inhibitors for clinical application
- Early Optic Nerve Head Glial Proliferation And JAK-Stat Pathway Activation In Chronic Experimental Glaucoma
- EBV-encoded LMP1 indirectly activates the Jak/Stat pathway through production of IFN-γ
- Ecpirm, A Potential Therapeutic Agent For Cutaneous T-Cell Lymphoma, Inhibits Cell Proliferation And Promotes Apoptosis Via A Jak/Stat Pathway
- Eef1a2 promotes cell growth, inhibits apoptosis and activates Jak/Stat and AKT signaling in mouse plasmacytomas
- Effect of AG490 and Rapamycin on Jak/Stat signal passage in Klebsiella pneumonia multiple organ injury aged rats
- Effect of Anti‐IL‐2Rα Antibody on IL‐2‐induced Jak/Stat Signaling
- Effect of Astragalus and Salvia’s effective components and their compatibility on Jak/Stat pathway
- Effect Of Biologicals And JAK Inhibitors During Pregnancy On Health-Related Outcomes In Children Of Women With Inflammatory Bowel Disease.
- Effect Of Compound Yuxingcao On Renal Injury Of Db/Db Mice And Some Genes Of Jak/Stat Pathway
- Effect Of Cornel Iridoid Glycoside On Microglia Activation Through Suppression Of The Jak/Stat Signalling Pathway
- Effect of curcumin on JAK-STAT signaling pathway in hepatoma cell lines
- Effect Of Dexmedetomidine Pretreatment On Activation Of Jak/Stat Signaling Pathway During Intestinal Injury In Rats Undergoing Liver Transplantation
- Effect of Electroacupuncture on JAK-STAT Signal Transduction Pathway in Chondrocyte of Osteoarthritis Rats
- Effect Of Electroacupuncture Stimulation Of” Housanli”(St 36) And” Zhongwan”(Cv 12) On Serum Leptin And Hepatocellular JAK 2-Stat 3 Signaling In Obese Rats
- Effect Of Interleukin-6 On Proliferation In Primary Cultured Chicken Hepatocytes: Involvement Of Jak/Stat, Pkc, And P44/42 Mapks
- Effect Of JAK Inhibitors On Release Of Cxcl9, Cxcl10 And Cxcl11 From Human Airway Epithelial Cells
- Effect of Jak/Stat pathway activation on high glucose-induced transdifferentiation in renal proximal tubular epithelial cells
- Effect of Jak/Stat pathway in atherosclerosis [J]
- Effect of Jak/Stat pathway on renal ischemia-reperfusion injury in rats
- Effect of Jak/Stat signaling pathway on extracellular release of HMGB1 in lipopolysaccharide-induced hepatocytes
- Effect Of Jak/Stat-Pparg Receptor Modulator In Intracerebral Penduncle Ethidium Bromide Induced Experimental Model Of …
- EFFECT OF JAK-STAT3 AND EGFR-STAT3 SIGNAL TRANSDUCTION PATHWAYS IN THE DEVELOPMENT OF NON-SMALL CELL LUNG CANCER [J]
- Effect of JAK-Yak Tang water extract on expression of cytokin and chemokine
- Effect Of Liraglutide On The Janus Kinase/Signal Transducer And Transcription Activator (Jak/Stat) Pathway In Diabetic Kidney Disease In Db/Db Mice And In Cultured …
- Effect Of Liuweibuqi Capsules In Pulmonary Alveolar Epithelial Cells And Copd Through Jak/Stat Pathway
- Effect Of Methotrexate On Jak/Stat Pathway Activation In Myeloproliferative Neoplasms
- Effect Of Mir-153-Targeted Prdm2 On Invasion And Migration Abilities Of Bladder Cancer Cells By Jak/Stat Signaling Pathway
- Effect Of Mir-19A And Mir-21 On The Jak/Stat Signaling Pathway In The Peripheral Blood Mononuclear Cells Of Patients With Systemic Juvenile Idiopathic …
- Effect of oxymatrine on Jak/Stat iteral in rat lung tissue with sepsis
- Effect Of Pm2. 5 On Oxidative Stress-Jak/Stat Signaling Pathway Of Human Bronchial Epithelial Cells
- Effect Of Propofol On Myocardial Ischemia/Reperfusion Injury In Rats Through Jak/Stat Signaling Pathway
- Effect Of Rhizoma Paridis Total Saponins On Apoptosis Of Colorectal Cancer Cells And Imbalance Of The Jak/Stat3 Molecular Pathway Induced By Il-6 …
- Effect of scutellarin on Jak/Stat pathway in myocardial ischemia reperfusion rats (LB561)
- Effect Of Selected Microenvironmental Factors On Colony Growth And Cross Infectional Ability Of Fungal Pathogens Causing Root Rot Disease Of JAK (Artocarpus …
- Effect of simvastatin on high glucose-and angiotensin II-induced activation of the Jak/Stat pathway in mesangial cells
- Effect of tetramethylpyrazine on JAK-STAT signal transduction in cardiomyocyte hypertrophy
- Effect of total glucosides of paeony on activation of Jak/Stat pathway in the kidney from diabetic rat [J]
- Effect Of Uvb Irradiation On JAK-Stat Pathway And Il-6, L-8 In Human Umbilical Vein Endothelial Cells
- Effect of Yishen Capsule on Activation of Jak/Stat Signal Transduction of Renal Tissue in the Diabetic Nephropathy Rats
- Effect of Yishen Capsule on Jak/Stat Signaling Pathway α-SMA, FN Expression in Rats with Diabetic Nephropathy
- Effects Of 3 Kinds Of Serum Containning Blood-Activating And Stasis-Eliminating Tcm Compound Formu-Las On Jak/Stat Signal Pathway Of Glioma U251 Cells
- Effects of 5-fluorouracil and gemcitabine on a breast cancer cell line (MCF-7) via the Jak/Stat pathway
- Effects Of Aerobic Exercise On Molecular Aspects Of Asthma: Involvement Of Socs-JAK-Stat.
- Effects of AG490 and S3I‑201 on regulation of the Jak/Stat3 signaling pathway in relation to angiogenesis in TRAIL‑resistant prostate cancer cells in vitro
- Effects of Bletilla Striata Polysaccharide on Jak/Stat Signaling Pathway in Oxidative Damaged Human Keratinocyte
- Effects Of Di-(2-Ethylhexyl) Phthalate On Lipid Metabolism By The Jak/Stat Pathway In Rats
- Effects of fluvastatin on the expression of Janus kinase 2/signal transducers and activators of transcription (Jak/Stat) in glomerular mesangial cells under high …
- Effects of fucoxanthin on proliferation and apoptosis in human gastric adenocarcinoma MGC-803 cells via Jak/Stat signal pathway
- Effects of interferon-[] on activation of the Jak/Stat signal transduction pathway and regulation of ovine endometrial gene expression
- Effects Of JAK 1/2 Inhibition On Bone Marrow Stromal Cells Of Myeloproliferative Neoplasm (Mpn) Patients And Healthy Individuals
- Effects of Jak/Stat3-involved eNOS gene transfer on angiogenesis after myocardial infarction
- Effects of JAK-STAT inhibitors on glucocorticosteroid resistant release of CXCR3 chemokines from human bronchial epithelial cells
- Effects Of JAK-Stat Signaling Pathway, Il-1Βand Il-6 On Injury Of Pc12 Cells With X-Ray Irradiation
- Effects of Ling Qi Juan Gan capsule drug-containing serum on PDGF-induced proliferation and Jak/Stat signaling of HSC-T6 cells
- Effects Of Long Non-Coding Rna Rp11-468E2.5 On Cell Proliferation And Apoptosis In Colorectal Cancer Cells By Targeting Stat5 And Stat6 Via The Jak/Stat Signaling Pathway
- Effects of matrine on JAK-STAT signaling transduction pathways in bleomycin-induced pulmonary fibrosis
- Effects Of Purified Omphalia Lapidescens Protein On Metastasis, Cell Cycle, Apoptosis And The JAK-Stat Signaling Pathway In Sgc-7901 Human Gastric Cells
- Effects Of Rituximab On JAK-Stat And Nf-Κb Signaling Pathways In Acute Lymphoblastic Leukemia And Chronic Lymphocytic Leukemia
- Effects Of Shellfish Polysaccharide On The Molecular Expression Of JAK-Stat Transduction Pathways In Hepg2. 2.15 Cells
- Effects of sodium valproate on RPMI8226 and U266 cell proliferation and IL-6/Jak/Stat signaling pathway [J]
- EFFECTS OF TETRAMETHYLPYRAZINE ON JAK-STAT SIGNAL TRANSDUCTION IN CARDIOMYOCYTE HYPERTROPHY
- Effects of The Inhibitor of Jak/Stat on the Function of Rat Hearts After Myocardial Ischemia-reperfusion
- Effects Of Total Flavonoids From Oxytropis Falcata Bunge On The Socs/Jak/Stat Inflammatory Signaling Pathway In The Kidneys Of Diabetic Nephropathy Model Mice
- Effects of TSA on Cerebral ischemia/reperfusion injury via Jak/Stat signal pathway in rats
- Efficacy Of Anti-JAK Inhibitors In Ulcerative Colitis
- Efficacy Of Monotherapy With Biologics And JAK Inhibitors For The Treatment Of Rheumatoid Arthritis: A Systematic Review
- EGCG mitigates neurotoxicity mediated by HIV-1 proteins gp120 and Tat in the presence of IFN-γ: Role of Jak/Stat1 signaling and implications for HIV-associated …
- EGFR, Wingless and Jak/Stat signaling cooperatively maintain Drosophila intestinal stem cells
- EGFR-induced cell migration is mediated predominantly by the JAK-STAT pathway in primary esophageal keratinocytes
- Electroacupuncture effect on neurological behavior and tyrosine kinase-JAK 2 in rats with focal cerebral ischemia
- Ellagic Acid Ameliorates Renal Ischemic-Reperfusion Injury Through Nox4/Jak/Stat Signaling Pathway
- Eltd1 Facilitates Glioma Proliferation, Migration And Invasion By Activating Jak/Stat3/Hif-1Α Signaling Axis
- Elucidating The Role Of Cytokine Signaling In The Homeostasis Of Innate Immune Cells With JAK Inhibitors
- Elucidating The Role Of Jak/Stat Signalling In Polycythaemia Vera And Essential Thrombocythaemia Using Proteomics
- Elucidation Of Mechanisms Underlying Metastatic Melanoma Immune Escape Via Suppression Of Major Histocompatibility Complex (Mhc) Ii Through Dysregulation Of The Jak/Stat Pathway
- Emerging Drugs For Alopecia Areata: JAK Inhibitors
- Emerging roles of JAK–STAT signaling pathways in adipocytes
- Emerging therapeutic paradigms to target the dysregulated Jak/Stat pathways in hematological malignancies
- Emerging Therapies For Atopic Dermatitis: JAK Inhibitors
- Emerging Topical And Systemic JAK Inhibitors In Dermatology
- Emodin Potentiates The Antiproliferative Effect Of Interferon Α/Β By Activation Of Jak/Stat Pathway Signaling Through Inhibition Of The 26S Proteasome
- Emulsified isoflurane induces postconditioning against myocardial infarction via JAK-STAT pathway
- Endothelial Cell Proteomic Response To Rickettsia Conorii Infection Reveals Activation Of The Janus Kinase (Jak)-Signal Transducer And Activator Of Transcription (Stat) …
- Endothelial Discoidin Domain Receptor 2 Promote Angiogenesis Through JAK-Stat3 Signaling Pathway
- Endothelial Transcriptomic Changes Induced By Oxidized Low Density Lipoprotein Disclose An Up-Regulation Of Jak–Stat Pathway
- Endotoxin-activated microglia injure brain derived endothelial cells via NF-κB, JAK-STAT and JNK stress kinase pathways
- Engagement of the B-cell antigen receptor activates STAT through Lyn in a JAK-independent pathway
- Engineered Aedes Aegypti Jak/Stat Pathway-Mediated Immunity To Dengue Virus
- Enhanced Inflammatory Damage By Microrna-136 Targeting Klotho Expression In Hk-2 Cells By Modulating Jak/Stat Pathway
- Enhanced Uropathogenic Escherichia Coli-Induced Infection In Uroepithelial Cells By Sugar Through Tlr-4 And Jak/Stat1 Signaling Pathways
- Enhancement Of Cetuximab-Induced Radiosensitization By JAK-1 Inhibition
- Enhancer Of Polycomb And The Tip60 Complex Repress Hematological Tumor Initiation By Negatively Regulating Jak/Stat Pathway Activity
- Enrichment Of The Janus Kinase (Jak) Activation Signature In Severe Asthma Sputum: Correlation With Il-13 Expression
- Enterovirus 71 Suppresses Interferon Responses By Blocking Jak/Stat Signaling Through Inducing Karyopherin-Α1 Degradation
- Enterovirus 71 Suppresses Interferon Responses By Blocking Janus Kinase (Jak)/Signal Transducer And Activator Of Transcription (Stat) Signaling Through Inducing …
- Entrepreneurship as a complex category. How to develop it?(Przedsiebiorczosc jako kategoria zlozona. JAK ja rozwijac?)
- Enzastaurin has anti-tumour effects in lung cancers with overexpressed JAK pathway molecules
- Ephrin-A1 induces tumor cell migration via a Rho GTPase and JAK kinase-dependent pathway
- Epigallocatechin‐3‐Gallate Induces Cell Apoptosis In Chronic Myeloid Leukaemia By Regulating Bcr/Abl‐Mediated P38‐Mapk/Jnk And JAK 2/Stat 3/Akt …
- Epigenetic dysregulation of the Jak/Stat pathway by frequent aberrant methylation of SHP1 but not SOCS1 in acute leukaemias
- Epigenetic Regulator Lid Maintains Germline Stem Cells Through Regulating JAK-Stat Signaling Pathway Activity
- Epigenetic silencing of a potential tumor suppressor NR4A3 by aberrant Jak/Stat signaling predicts prognosis in gastric cancer
- Epigenetic Silencing Of Socs5 Potentiates Jak‐Stat Signaling And Progression Of T‐Cell Acute Lymphoblastic Leukemia
- Epigenetic Silencing Of The Nr4A3 Tumor Suppressor, By Aberrant Jak/Stat Signaling, Predicts Prognosis In Gastric Cancer
- EPSTEIN BARR VIRUS ENCODED LATENT MEMBRANE PROTEIN 1 ACTIVATES THE Jak/Stat PATHWAY INDIRECTLY THROUGH PRODUCTION OF IFN-G …
- ER stress and neuroinflammation: connecting the unfolded protein response to Jak/Stat signaling (P5196)
- Eriobotrya Japonica Water Extract Characterization: An Inducer Of Interferon-Gamma Production Mainly By The JAK-Stat Pathway
- Erlotinib Is Not Effective In Patients (Pts) With JAK-2 V617F Positive Polycythemia Vera
- Erratum: The Jak/Stat3 Signaling Pathway Mediates Inhibition Of Host Cell Apoptosis By Chlamydia Psittaci Infection
- Erythropoietin resistance contributes to anaemia in chronic heart failure and relates to aberrant JAK–STAT signal transduction
- Erythropoietin-mediated activation of JAK-STAT signaling contributes to cellular invasion in head and neck squamous cell carcinoma
- Erythropoietin-mediated protection of insect brain neurons involves JAK and STAT but not PI3K transduction pathways
- Essential Role Of Endocytosis For Interleukin-4-Receptor-Mediated Jak/Stat Signalling
- Essential role of Jak/Stat pathway in the induction of cell cycle arrest in macrophages infected with periodontopathic bacterium Aggregatibacter …
- Essential role of the Jak/Stat1 signaling pathway in the expression of inducible nitric-oxide synthase in intestinal epithelial cells and its regulation by butyrate
- Establishment of a Ewing’s sarcoma mouse model: Jak/Stat signalling in Ewing’s sarcoma
- Estimate Of JAK 2 V617F Mutation And Activity Of Catalase Enzyme In Myeloproliferative Neoplasm
- Estradiol recovers hepatic IGF-I gene expression in growth hormone resistant mice through activation of the JAK-STAT pathway
- ET-35PACRITINIB: A NOVEL Jak/Stat INHIBITOR WITH TRANSLATIONAL RELEVANCE FOR GBM
- Ethanol inhibits the JAK-STAT signaling pathway in freshly isolated rat hepatocytes but not in cultured hepatocytes or HepG2 cells: evidence for a lack of involvement …
- Evaluating The Role Of JAK pathways In Platelet Homeostasis Using A Systems Modeling Approach
- Evaluation Of Prevalence Of JAK 2 Exon 12 Gene Mutations Among Iranian Patients With Polycythemia Vera
- Evaluation of the hypoglycemic and hypolipidemic effects of an ethylacetate fraction of Artocarpus heterophyllus (jak) leaves in streptozotocin-induced …
- Evidence For A Non-Canonical Jak/Stat Signaling Pathway In The Synthesis Of The Brain’S Major Ion Channels And Neurotransmitter Receptors
- Evidence For Janus Kinase (Jak) Inhibitors For The Prevention Of Major Morbid Events In Patients With Myeloproliferative Neoplasms (Mpns)
- Evidence for the involvement of Jak/Stat/SOCS pathway in the mechanism of Tangshen formula-treated diabetic nephropathy
- Evidence for tissue-specific Jak/Stat target genes in Drosophila optic lobe development
- Evolution of JAK and stat proteins
- Evolution of JAK-STAT pathway components: mechanisms and role in immune system development
- Evolution of the JAK-STAT pathway
- Evolutionary analysis for functional divergence of JAK protein kinase domains and tissue-specific genes
- Exercise rescued chronic kidney disease by attenuating cardiac hypertrophy through the cardiotrophin-1→ LIFR/gp 130→ Jak/Stat3 pathway
- Exogenous expression of WT1 gene influences U937 cell biological behaviors and activates MAPK and JAK-STAT signaling pathways
- Exogenous Hydrogen Sulfide Attenuates High Glucose-Induced Injury By In-Hibiting Jak/Stat Pathway In Human Umbilical Vein Endothelial Cells
- Exogenous Mscs Ameliorate Hypoxia/Reoxygenation Injury In Renal Tubular Epithelial Cells Through Jak/Stat Signaling Pathway-Mediated Regulation Of …
- Exploration Of 3, 6-Dihydroimidazo (4, 5-D) Pyrrolo (2, 3-B) Pyridin-2 (1H)-One Derivatives As JAK Inhibitors Using Various In Silico Techniques
- Expression Analysis Of Micro Rna‐125 In Patients With Polycythemia Vera And Essential Thrombocythemia And Correlation With JAK 2 Allele Burden And Laboratory …
- Expression and characterization of the JAK kinase and STAT protein from brine shrimp, Artemia franciscana
- EXPRESSION AND SIGNIFICANCE OF TYROSINE PROTEIN KINASE IN MAPK AND JAK-STAT PATHWAYS IN HEPATOCELLULAR CARCINOMA TISSUE [J]
- Expression levels of the Jak/Stat pathway in the transition from hormone-sensitive to hormone-refractory prostate cancer
- Expression of ATRAP in adipocytes and negative regulation by β-adrenergic stimulation of Jak/Stat
- Expression of EGFR and molecules downstream to PI3K/Akt, Raf-1-MEK-1-MAP (Erk1/2), and JAK (STAT3) pathways in invasive lung adenocarcinomas resected at a …
- Expression of galectin-9 by IFN-γ stimulated human nasal polyp fibroblasts through MAPK, PI3K, and Jak/Stat signaling pathways
- Expression of Jak/Stat signal pathway in collagen-induced rat rheumatoid arthritis
- Expression of Jak/Stat Signal Pathway in Myocardial Injury of Ischemia Reperfusion in Rats [J]
- Expression of Jak/Stat signal transduction pathway and the effects of rapamycin in lupus nephritis-prone MRL/lpr mice
- Expression of Leptin’s inhibition to rat primary adipocytes perilipin mRNA through JAK-STAT3 signaling pathway
- Expression of Leptin’s inhibition to rat primary adipocytes perilipin mRNA through JAK-STAT3 signaling pathway [J]
- Expression Of Nephronectin Is Inhibited By Oncostatin M Via Both Jak/Stat And Mapk Pathways
- Expression Of The Jak/Stat Signaling Pathway In Bullous Pemphigoid And Dermatitis Herpetiformis
- Expression Of The Jak/Stat Signaling Pathway In The Ligamentum Flavum Of Patients With Lumbar Spinal Canal Stenosis
- Expression of the Jak/Stat3/SOCS3 signaling pathway in herniated lumbar discs
- Expression Patterns Of Three Jak–Stat Pathway Genes In Feather Follicle Development During Chicken Embryogenesis
- Extended JAK activation and delayed STAT1 dephosphorylation contribute to the distinct signaling profile of CNS neurons exposed to interferon-gamma
- Extermination Of Obsolete Relationship Through Ktmin-JAK-Maxam Algorithm In Confusion Mining
- Eye transformer is a negative regulator of Drosophila Jak/Stat signaling
- EZH2-mediated inactivation of IFN-γ-JAK-STAT1 signaling is an effective therapeutic target in MYC-driven prostate cancer
- Factor VIIa: TF induces activation of the Jak/Stat pathway; inflammatory signaling via non-inflammatory receptors
- Fairytale Fantasy, Secondary History, And Female Empowerment: Discovering The Many Dimensions Of Anna Brzezińska’S Wody Głębokie JAK Niebo
- Falcarindiol impairs the expression of inducible nitric oxide synthase by abrogating the activation of IKK and JAK in rat primary astrocytes
- Falcarindiol Inhibits Lps-Induced Inflammation Via Attenuating Mapk And JAK-Stat Signaling Pathways In Murine Macrophage Raw 264.7 Cells
- Farnesol Contributes To Intestinal Epithelial Barrier Function By Enhancing Tight Junctions Via The Jak/Stat3 Signaling Pathway In Differentiated Caco-2 Cells
- Feedback inhibition of Jak/Stat signaling by apontic is required to limit an invasive cell population
- Fgf2 Alleviates Ptsd Symptoms In Rats By Restoring Glast Function In Astrocytes Via The Jak/Stat Pathway
- Fgfr2 Promotes Expression Of Pd-L1 In Colorectal Cancer Via The Jak/Stat3 Signaling Pathway
- FGFR3 down-regulates PTH/PTHrP receptor gene expression by mediating Jak/Stat signaling in chondrocytic cell line
- Filgotinib In Crohn’S Disease: JAK Is Back
- Filozofia Jako Rewidowanie: JAK Niemiecki Idealizm Nabrał Wymiaru Historycznego W Myśli Odosobnionego Filozofa Amerykańskiego
- First-In-Class, Oral Small Molecule Inhibitor Of Mdm2, For The Treatment Of Patients With Myelofibrosis (Mf) Who Have Previously Received Treatment With A JAK …
- FISH and mutational screening of the ABL, SYK and JAK tirosine kinase family genes in BCR-ABL1 negative and V617FJAK2 negative chronic myeloproliferative …
- FISH and mutational screening of the Abl, Syk and JAK tyrosine kinase family genes in BCR-ABL1 negative and JAK2V617F negative chronic myeloproliferative …
- Flow Cytometric Monitoring of JAK-STAT Signal Transduction within Melanoma Cells
- Fluvastatin inhibits activation of JAK and STAT proteins in diabetic rat glomeruli and mesangial cells under high glucose conditions1
- Folic Acid Alters Methylation Profile Of JAK-Stat And Long-Term Depression Signaling Pathways In Alzheimer’S Disease Models
- Follistatin‐Like Protein 1 Induction Of Matrix Metalloproteinase 1, 3 And 13 Gene Expression In Rheumatoid Arthritis Synoviocytes Requires Mapk, Jak/Stat3 And Nf‐Κb …
- Formal modelling of toll like receptor 4 and Jak/Stat signalling pathways: insight into the roles of socs-1, interferon-β and proinflammatory cytokines in sepsis
- Forsythiaside a induced ifn-α and up-regulated correlation factors of JAK-stat signaling pathways in vitro
- Forsythiaside A induced IFN-α and up-regulated correlation factors of JAK-STAT signaling pathways in vitro.
- Forsythin inhibits lipopolysaccharide-induced inflammation by suppressing JAK-STAT and p38 MAPK signalings and ROS production
- Fractalkine upregulates inflammation through CX3CR1 and the Jak–Stat pathway in severe acute pancreatitis rat model
- Fractalkine upregulates intercellular adhesion molecule-1 in endothelial cells through CX3CR1 and the JAK–STAT5 pathway
- Fractalkine/Cx3Cr1 Axis Modulated The Development Of Pancreatic Ductal Adenocarcinoma Via Jak/Stat Signaling Pathway
- Fragment-Based Discovery Of 6-Arylindazole JAK Inhibitors
- Fragment-based discovery of JAK-2 inhibitors
- FRAP; RAFT1); Janus kinase-2 (JAK-2)
- Frequency and prognostic implications of JAK 1-3 aberrations in Down syndrome acute lymphoblastic and myeloid leukemia
- Fri0141 Efficacy Of JAK-Inhibitors Versus Biologic Dmards On Quality Of Life In Rheumatoid Arthritis: A Meta Analysis Of Randomized …
- Fri0146 Survival Of JAK Inhibitors: Real-World Data From The Biobadaser Iii Registry
- Fri0153 Ophthalmological Adverse Events Under JAK Inhibitors In Patients With Rheumatoid Arthritis: Case Analysis Of The …
- Fri0189 Comparison Of Gene-Expression Modification Profiles Between Targeting Il-6 And Targeting JAK Treatment: Effecting Common Biological Processes Or …
- From Vaquez to Dameshek through JAK… 2 much for polycythemia vera to be feared?
- Fucoidan regulates IFN-γ–induced NO and iNOS production differently in C6 glioma cells and RAW264. 7 cells: the involvement of Jak/Stat, p38 activation and TNF …
- Functional Analysis of Stat4 in Tumor Immunity by Inhibitory Jak/Stat in Vitro
- Functional conservation of suppressors of cytokine signaling proteins between teleosts and mammals: Atlantic salmon SOCS1 binds to Jak/Stat family members and …
- Functional cross-talk between the cyclic AMP and Jak/Stat signaling pathways in vascular smooth muscle cells
- Functions of the Drosophila JAK-STAT pathway: Lessons from stem cells
- Fundi Mdawala/JAK Katarikawe
- FVIIa:TF Induces Cell Survival via G12/G13-Dependent Jak/Stat Activation and BclXL Production
- Galantamine Anti-Colitic Effect: Role Of Alpha-7 Nicotinic Acetylcholine Receptor In Modulating Jak/Stat3, Nf-Κb/Hmgb1/Rage And P-Akt/Bcl-2 Pathways
- Galectin-3 exerts cytokine-like regulatory actions through the JAK–STAT pathway
- Gallic Acid Has Anticancer Activity And Enhances The Anticancer Effects Of Cisplatin In Non‑Small Cell Lung Cancer A549 Cells Via The Jak/Stat3 Signaling Pathway
- GalNAc/Gal-binding Rhizoctonia solani agglutinin has antiproliferative activity in Drosophila melanogaster S2 cells via MAPK and Jak/Stat signaling
- G-CSF prevents cardiac remodeling after myocardial infarction by activating the JAK-Stat pathway in cardiomyocytes
- Gefitinib Represses JAK-Stat Signaling Activated By Crtc1-Maml2 Fusion In Mucoepidermoid Carcinoma Cells.
- Gene Alterations In Epigenetic Modifiers And JAK-Stat Signaling Are Frequent In Breast Implant-Associated Alcl.
- Gene alterations involving the CRLF2‐JAK pathway and recurrent gene deletions in D own syndrome‐associated acute lymphoblastic leukemia in Japan
- Gene And Protein Expression Profiles Of JAK-Stat Signalling Pathway In The Developing Brain Of The Ts1Cje Down Syndrome Mouse Model
- Gene Expression of Cytokine Pathway, JAK-Stat Signal Pathway and Neuroactive Ligand-receptor Pathway in Patients with Primary Sj gren′ s Syndrome.
- Gene Expression of Jak/Stat Pathway in Patients with Psoriasis
- Generating Regulatory T-Cells by a JAK-STAT’5 Kinase Inhibitor.
- Genes Encoding Members Of The Jak‐Stat Pathway Or Epigenetic Regulators Are Recurrently Mutated In T‐Cell Prolymphocytic Leukaemia
- Genetic Alterations Of Jak/Stat Cascade And Histone Modification In Extranodal Nk/T-Cell Lymphoma Nasal Type
- Genetic analysis of contributions of dorsal group and JAK-Stat92E pathway genes to larval hemocyte concentration and the egg encapsulation response in Drosophila
- Genetic And Chemical Modulators Of Jak/Stat Signalling In Cancer
- Genetic And Real-World Clinical Data, Combined With Empirical Validation, Nominate JAK-Stat Signaling As A Target For Alzheimer’S Disease Therapeutic …
- Genetic factors in chronic inflammation: single nucleotide polymorphisms in the STAT-JAK pathway, susceptibility to DNA damage and Crohn’s disease in a New …
- Genetic Variants In Il-6/Jak/Stat3 Pathway And The Risk Of Crc
- Genetic variation in the Jak/Stat/SOCS signaling pathway influences breast cancer-specific mortality through interaction with cigarette smoking and use of aspirin …
- Genome‐wide expression profiling in the Drosophila eye reveals unexpected repression of notch signaling by the Jak/Stat pathway
- Genome-wide RNAi analysis of Jak/Stat signaling components in Drosophila
- Genomic Analyses Reveal Recurrent Mutations In Epigenetic Modifiers And The Jak–Stat Pathway In Sézary Syndrome
- Genomic analysis highlights the role of the JAK-STAT signaling in the anti-proliferative effects of dietary flavonoid—’Ashwagandha’in prostate cancer cells
- Genomic Analysis Reveals Recurrent Deletion Of Jak‐Stat Signaling Inhibitors Hnrnpk And Socs1 In Mycosis Fungoides
- GFP reporters detect the activation of the Drosophila Jak/Stat pathway in vivo
- Ghrelin restoration of function in vitro in somatotropes from male mice lacking the Janus kinase (JAK)-binding site of the leptin receptor
- Giant Prolactinoma With JAK 2 Positive Mutation
- Gigantol Targets Cancer Stem Cells And Destabilizes Tumors Via The Suppression Of The Pi3K/Akt And Jak/Stat Pathways In Ectopic Lung Cancer Xenografts
- Ginsenoside Rh1 suppresses inducible nitric oxide synthase gene expression in IFN-γ-stimulated microglia via modulation of Jak/Stat and ERK signaling pathways
- Gkn2 Increases Apoptosis, Reduces The Proliferation And Invasion Ability Of Gastric Cancer Cells Through Down-Regulating The Jak/Stat Signaling Pathway
- Glial fibrillary tangles and Jak/Stat-mediated glial and neuronal cell death in a Drosophila model of glial tauopathy
- Glucagon-Like Peptide 1 Receptor Agonist Ameliorates The Insulin Resistance Function Of Islet Β Cells Via The Activation Of Pdx-1/JAK Signaling Transduction In …
- Glucocorticoids potentiate IL-6 induced SP-B expression in H441 cells by enhancing the Jak/Stat signaling pathway
- Glucocorticoids potentiate IL-6-induced SP-B expression in H441 cells by enhancing the JAK-STAT signaling pathway
- Glycosylation-Dependent Ifn-Γr Partitioning In Lipid And Actin Nanodomains Is Critical For JAK Activation
- Glycyrrhizin Inhibits Ifn-Γ-Induced Cxcl10 By Suppressing The Jak/Stat1 Signal Pathway In Hacat Cells
- Glypicans regulate Jak/Stat signaling and distribution of the Unpaired morphogen
- GM-CSF activates the Jak/Stat pathway to rescue polymorphonuclear neutrophils from spontaneous apoptosis in young but not elderly individuals
- Going with the flow: JAK-STAT signaling in JMML
- Gram Domain-Containing Protein 1B (Gramd1B) As A Novel Regulator Of Jak/Stat Signaling Mediated Tumorigenesis
- Gram Domain-Containing Protein 1B (Gramd1B), A Novel Component Of The Jak/Stat Signaling Pathway, Functions In Gastric Carcinogenesis
- Gramd1B Regulates Cell Migration In Breast Cancer Cells Through Jak/Stat And Akt Signaling
- Granulocyte macrophage-colony stimulating factor shows anti-apoptotic activity in neural progenitor cells via Jak/Stat5-Bcl-2 pathway
- Granulocytes And Mono-Nuclear Cells From Patients With Myeloproliferative Disorders Harbour Persistent Evidence Of Dna Damage And Tp53 Pathway Activation That Correlates With JAK-Stat Activation
- Granuloma Annulare Skin Profile Shows Activation Of Th1, Th2, And JAK pathways
- Green Synthesis Of Gold Nanoparticles Using Euphrasia Officinalisleaf Extract To Inhibit Lipopolysaccharide-Induced Inflammation Through Nf-Κb And Jak/Stat Pathways In Raw 264.7 Macrophages
- Growing Evidence Of The Safety Of JAK Inhibitors In Patients With Rheumatoid Arthritis
- Growth hormone receptor interaction with JAK proteins differs between tissues
- Growth hormone resistance in uremia, a role for impaired Jak/Stat signaling
- Growth hormone synergizes with BMP9 in osteogenic differentiation by activating the Jak/Stat/IGF1 pathway in murine multilineage cells
- Growth hormone/JAK‐STAT axis signal‐transduction defect: A novel treatable cause of growth failure
- Growth hormone-induced production of cytokines in murine peritoneal macrophages in vitro: role of Jak/Stat, PI3K, PKC and MAP kinases
- Growth hormone-stimulated insulin-like growth factor-1 expression in rainbow trout (Oncorhynchus mykiss) hepatocytes is mediated by ERK, PI3K-AKT, and JAK …
- Growth Inhibition Effect Of Matrine On K562 Cells Mediated By Il-6/Jak/Stat3 Signaling Pathway
- Growth restriction in the rat alters expression of cardiac Jak/Stat genes in a sex-specific manner
- Guggulsterone decreases proliferation and metastatic behavior of pancreatic cancer cells by modulating Jak/Stat and Src/FAK signaling
- Guidelines For The Design Of Packaging For Handmade Products. Ruean-Thai JAK-San Group, Sri-Pran, Sawang-Ha, Ang Thong
- Guidelines For The Design Of Souvenirs From Woven Line Plastic Fiber: Ruean-Thai JAK-San Group, Sri-Pran, Sawang-Ha, Ang Thong
- Gα73B is a downstream effector of Jak/Stat signalling and a regulator of Rho1 in Drosophila haematopoiesis
- H3K27 Methylation Dynamics During Cd4 T Cell Activation: Regulation Of Jak/Stat And Il12Rb2 Expression By Jmjd3
- Haematological cancer: Hit the lymphoma, JAK
- Hair Growth Is Induced By Blockade Of Macrophage-Derived Oncostatin M And Downstream JAK-Stat5 Signaling In Hair Follicle Stem Cells
- Hamlet po fińsku, czyli JAK Szekspir z Kaurismäkim
- HCMV activates the IL-6-JAK-STAT3 axis in HepG2 cells and primary human hepatocytes
- HCV structural proteins interfere with interferon-alpha Jak/Stat signalling pathway
- Heat‐Shock Transcription Factor 1 Is Critically Involved In The Ischaemia‐Induced Cardiac Hypertrophy Via JAK 2/Stat 3 Pathway
- Helicobacter pylori CagA phosphorylation status determines the gp130-activated SHP2/ERK and Jak/Stat signal transduction pathways in gastric epithelial cells
- Hemorrhagic Shock Sensitized The Diaphragm To Ventilator-Induced Dysfunction Through The Activation Of Il-6/Jak/Stat Signaling-Mediated Autophagy In Rats
- Hepatic expression of the GH/Jak/Stat/IGF pathway, acute-phase response signalling and complement system are affected in mouse offspring by prenatal and early …
- Hepatitis C virus core protein differently regulates the JAK-STAT signaling pathway under interleukin-6 and interferon-γ stimuli
- Hepatitis C virus core protein modulates the interferon-induced transacting factors of Jak/Stat signaling pathway but does not affect the activation of downstream IRF-1 …
- Hepatitis C virus targets the interferon‐α Jak/Stat pathway by promoting proteasomal degradation in immune cells and hepatocytes
- Hepatitis C Virus-Mediated Enhancement Of Microrna Mir-373 Impairs The Jak/Stat Signaling Pathway
- Herpes simplex virus-1 infection causes the secretion of a type I interferon-antagonizing protein and inhibits signaling at or before JAK-1 activation
- Herpes Zoster In Patients Receiving JAK Inhibitors For Ulcerative Colitis: Mechanism, Epidemiology, Management, And Prevention
- Hes binding to STAT3 mediates crosstalk between Notch and JAK–STAT signalling
- Heterochromatin Protein 1 (Hp1) Inhibits Stem Cell Proliferation Induced By Ectopic Activation Of The Jak/Stat Pathway In The Drosophila Testis
- Hif-3Α1 Promotes Colorectal Tumor Cell Growth By Activation Of JAK-Stat3 Signaling
- High Pim1 Expression Is A Biomarker Of T-Cell Acute Lymphoblastic Leukemia With Jak/Stat Activation Or T (6; 7)(P21; Q34)/Trb@-Pim1 Rearrangement
- High throughput screening, with a flow cytometry automated platform (ex vivo biotech), to identify potential combination partners, for the JAK 2 inhibitor ruxolitinib
- High-Throughput Analysis Of Mapk And JAK-Stat Signaling In Ct26 Tumors Using A Combination Of Immunophenotyping And Phospho-Flow Cytometry
- Hip Hop: Hipk Promotes Tumourigenesis In Drosophila Through Jak/Stat Signaling
- Hipk Is Required For Jak/Stat Activity And Promotes Hemocyte-Derived Tumorigenesis
- Hipk Is Required For Jak/Stat Activity During Development And Tumorigenesis.
- Hispidulin Suppresses Cell Growth And Metastasis By Targeting Pim1 Through Jak2/Stat3 Signaling In Colorectal Cancer
- Histamine utilizes JAK–STAT pathway in regulating cytokine production
- Histone deacetylase 6 (HDAC6) as a new modulator of the Jak/Stat pathway in melanoma.
- Histone demethylase dUTX antagonizes JAK-STAT signaling to maintain proper gene expression and architecture of the Drosophila testis niche
- Hiv-1 Promotes The Degradation Of Components Of The Type 1 Ifn Jak/Stat Pathway And Blocks Anti-Viral Isg Induction
- HIV-1 Tat-mediated induction of CCL5 in astrocytes involves NF-κB, AP-1, C/EBPα and C/EBPγ transcription factors and JAK, PI3K/Akt and p38 MAPK …
- HO-1 and JAK-2/STAT-1 signals are involved in preferential inhibition of iNOS over COX-2 gene expression by newly synthesized tetrahydroisoquinoline alkaloid …
- Ho-1 Overexpressed Mesenchymal Stem Cells Ameliorate Sepsis-Associated Acute Kidney Injury By Activating Jak/Stat3 Pathway
- Honokiol Eliminates Glioma/Glioblastoma Stem Cell-Like Cells Via JAK-Stat3 Signaling And Inhibits Tumor Progression By Targeting Epidermal Growth Factor …
- Honokiol Inhibits Sphere Formation And Xenograft Growth Of Oral Cancer Side Population Cells Accompanied With Jak/Stat Signaling Pathway Suppression And …
- Hormesis Of Mercuric Chloride-Human Serum Albumin Adduct On N9 Microglial Cells Via The Erk/Mapks And Jak/Stat3 Signaling Pathways
- Host Jak/Stat Activity Is A Target Of Endoparasitoid Wasp Virulence Strategies
- How ard Giles JAK e Harw ood
- HOW DO ONOMASTS WRITE ABOUT PROPER NAMES? AN ATTEMPT AT METAONOMASTIC REFLECTION (‘Plon niesiemy, plon…’JAK onomasci pisza o nazwach …
- HOW DO ROMA REMEMBER?(JAK Romowie pamietaja?)
- How many JAK inhibitors in myelofibrosis?
- How nature created its own nuclear reactor; JAK si priroda vytvorila svuj vlastni jaderny reaktor
- HOW TO APPROACH DEVELOPMENT OF ENTERPRISE INFORMATION SYSTEM JAK PŘISTUPOVAT K VÝVOJI PODNIKOVÉHO INFORMAČNÍHO …
- How To Bring A Building Back From Ruins/JAK Wyprowadzić Budynek Z Ruiny?
- How to calibrate dosimetric instruments; JAK wzorcowac aparature dozymetryczna?
- HOW TO COMPOSE A MOTET FOR THE VIRGIN. JOSQUIN DES PREZ AND HIS MOTET’ILLIBATA DEI VIRGO NUTRIX'(JAK skomponowac motet ku czci Dziewicy …
- How To Define Treatment Failure For JAK Inhibitors
- How to go on with Czech uranium: does current uranium mining in the Czech Republic cover Czech nuclear power plants’ needs?; JAK dal s ceskym uranem-zajistuje …
- How To Kill The Street Without Destroying The Buildings JAK „Zabić” Ulicę Bez Niszczenia Budynków
- How to translate a service system into customers’ quality experience?(JAK przelozyc system uslugowy na doswiadczenia jakosci klientow?)
- Hoxa11‐As Regulates Jak‐Stat Pathway By Mir‐15A‐3P/Stat3 Axis To Promote The Growth And Metastasis In Liver Cancer
- Hoxa9 Cooperates With Activated Jak/Stat Signaling To Drive Leukemia Development
- HPP1 tumor suppression and JAK-STAT signaling
- Hrani Možlyvoho: Ščo Može Zrobyty Ukraïna JAK Nelostijnyj Člen Rady Bezleky Oon?
- Hsp90 Inhibition Results In Gr, Ar And JAK Protein Degradation, Decreased Triple-Negative Breast Cancer Proliferation And Increased Paclitaxel Sensitivity
- HSP90 is essential for JAK-STAT signaling in classical Hodgkin lymphoma cells
- Hsp90 JAK-hammer
- HSV-1 Infection Causes the Secretion of a Type I Interferon-antagonizing Protein and Inhibits Signaling at or before JAK-1 Activation
- Htlv-1 Dysregulates Il-6 And Il-10-Jak/Stat Signaling And Induces Leukemia/Lymphoma Of Mature Cd4+ T Cells With Regulatory T-Cell-Like Signatures
- Human and rodent pancreatic β-cells express IL-4 receptors and IL-4 protects against β-cell apoptosis by activation of the PI3K and Jak/Stat pathways
- Human Bone-Marrow Derived Mesenchymal Stem Cells Home Via The Pi3K-Akt, Mapk, And Jak/Stat Signaling Pathways In Response To Pdgf
- Human cytokines activate JAK–STAT signaling pathway in porcine ocular tissue
- Human leptin signaling in human peripheral blood mononuclear cells: activation of the JAK-STAT pathway
- Human metapneumovirus inhibits the IL-6-induced Jak/Stat3 signalling cascade in airway epithelium
- Hydrogen Sulfide Attenuates Myocardial Fibrosis In Diabetic Rats Through The Jak/Stat Signaling Pathway
- Hydroxypropyltrimethyl Ammonium Chloride Chitosan Activates Raw 264.7 Macrophages Through The Mapk And JAK-Stat Signaling Pathways
- Hyperactivation of the Drosophila Hop JAK kinase causes the preferential overexpression of eIF1A transcripts in larval blood cells
- Hypermethylation associated with inactivation of the SOCS-1 gene, a Jak/Stat inhibitor, in human hepatoblastomas
- Hypermethylation of SOCS-1, A Suppressor in Jak/Stat Pathway, Associated with Chemoresistance and Early Recurrence in Patients with Ovarian Serous …
- Hypermethylation-associated Inactivation of the SOCS-1 Gene, a Jak/Stat Inhibitor, in Human Pancreatic Cancers
- Hyperprolactinemia-Inducing Antipsychotics Increase Breast Cancer Risk By Activating JAK-Stat5 In Precancerous Lesions
- Hypervirulent M. tuberculosis W/Beijing Strains Upregulate Type I IFNs and Increase Expression of Negative Regulators of the JAK-Stat Pathway
- Hypoglycaemic and Hypolipidaemic effect of an ethylacetate fraction of Artocarpus heterophyllus (jak) leaves in streptozotocin induced diabetic rats
- Hypothyroidism Decreases Jak/Stat Signaling Pathway In Lactating Rat Mammary Gland
- Hypoxia-Induced Activation Of Jak/Stat3 Signaling Pathway Promotes Trophoblast Cell Viability And Angiogenesis In Preeclampsia
- Hypoxic Conditioned Medium From Human Adipose‐Derived Stem Cells Promotes Mouse Liver Regeneration Through Jak/Stat3 Signaling
- Icaritin inhibits Jak/Stat3 signaling and growth of renal cell carcinoma
- Id: 163: Contribution Of The Jak/Stat Pathway To Neurodegenerative Diseases
- Identification and analysis of Jak/Stat pathway target genes in Drosophila melanogaster
- Identification And Analysis Of JAK-Stat Pathway Genes In Drosophila Melanogaster Immunity
- Identification and characterization of a novel class of JAK inhibitors and their application in targeting multiple myeloma
- Identification And Functional Characterization Of Interferon Regulatory Factor 7 Involved In Activation Jak/Stat Pathway In Miiuy Croaker
- Identification Of 2-Imidazopyridine And 2-Aminopyridone Purinones As Potent Pan-Janus Kinase (Jak) Inhibitors For The Inhaled Treatment Of Respiratory Diseases
- Identification Of A Jak/Stat Pathway Receptor Domeless From Pacific White Shrimp Litopenaeus Vannamei
- Identification of inhibitors that target JAK-STAT6 signal pathway via high-throughput screening [J]
- Identification of Jak/Stat pathway regulators—insights from RNAi screens
- Identification of Jak/Stat signalling components by genome-wide RNA interference
- Identification of JAK–STAT pathways as important for the anti-inflammatory activity of a Hypericum perforatum fraction and bioactive constituents in RAW 264.7 mouse …
- Identification Of JAK-Stat Signaling Involvement In Sarcoidosis Severity Via A Novel Microrna-Regulated Peripheral Blood Mononuclear Cell Gene Signature
- Identification Of Novel Regulators Of The Jak/Stat Signaling Pathway That Control Border Cell Migration In The Drosophila Ovary
- Identification of the first invertebrate interleukin Jak/Stat receptor, the Drosophila gene domeless
- Identification of the first patient with a confirmed mutation of the JAK-STAT system
- Identification of the Jak/Stat Proteins as Novel Downstream Targets of EphA4 Signaling in Muscle IMPLICATIONS IN THE REGULATION OF …
- Identification Of The JAK-Stat Pathway In Canine Splenic Hemangiosarcoma, Thyroid Carcinoma, Mast Cell Tumor, And Anal Sac Adenocarcinoma
- Identification of two novel regulators of the Drosophila JAK-STAT pathway, dPIAS and DeltaN-dSTAT, and their potential functional implications in development.
- IFI16 is an essential mediator of growth inhibition, but not differentiation, induced by the leukemia inhibitory factor/Jak/Stat pathway in medullary thyroid carcinoma …
- Ifitm1 Suppression Blocks Proliferation And Invasion Of Aromatase Inhibitor-Resistant Breast Cancer In Vivo By Jak/Stat-Mediated Induction Of P21
- IFN-y/Jak/Stat pathway-induced inhibition of DR4 and DR5 expression on endothelial cells is cancelled by cycloheximide-sensitive mechanism: Novel finding of …
- IFN-α and IFN-λ differ in their antiproliferative effects and duration of Jak/Stat signaling activity
- Ifn-Α Inhibits Adipogenesis Via Regulation Of Jak/Stat1 Signaling
- IFNγ signaling—Does it mean JAK–STAT?
- IFN-γ/Jak/Stat pathway-induced inhibition of DR4 and DR5 expression on endothelial cells is cancelled by cycloheximide-sensitive mechanism: Noble finding of …
- IFN-γ/Jak/Stat pathway-induced inhibition of DR4 and DR5 expression on endothelial cells is cancelled by cycloheximide-sensitive mechanism: novel finding of …
- IFN-γ-induced IL-27 and IL-27p28 expression are differentially regulated through JNK MAPK and PI3K pathways independent of Jak/Stat in human monocytic cells
- Ifnγ-Induced Jak/Stat-, But Not Nf-Κb-, Signaling
- Ifn-Γ-Induced Jak/Stat, But Not Nf-Κb, Signaling Pathway Is Insensitive To Glucocorticoid In Airway Epithelial Cells
- IFN-λ3 inhibits HIV infection of macrophages through the JAK-STAT pathway
- Ikaros dominant negative isoform (Ik6) induces IL-3-independent survival of murine pro-B lymphocytes by activating JAK-STAT and up-regulating Bcl-xl levels
- Il-10 And The JAK-Stat Pathway In The Regulation Of Metabolism And Mucosal Homeostasis
- Il-10 Improves Cardiomyocyte Survival Via Downstream Myd88-Dependent Tlr4 Innate Signaling Of Jak/Stat3 Pathway
- IL-12 p35 silenced dendritic cells modulate immune responses by blocking IL-12 signaling through JAK-STAT pathway in T lymphocytes
- IL‐15 regulates Bcl‐2 family members Bim and Mcl‐1 through Jak/Stat and PI3K/AKT pathways in T cells
- Il-17 Induces Reactive Astrocytes And Up-Regulation Of Vascular Endothelial Growth Factor (Vegf) Through Jak/Stat Signaling
- IL-17 markedly up-regulates β-defensin-2 expression in human airway epithelium via JAK and NF-κB signaling pathways
- Il1-Induced Jak/Stat Signaling Is Antagonized By Tgfβ To Shape Caf Heterogeneity In Pancreatic Ductal Adenocarcinoma
- Il-21 Enhances The Degradation Of Cartilage Through The JAK-Stat Signaling Pathway During Osteonecrosis Of Femoral Head Cartilage
- Il-21 Is Positively Associated With Intervertebral Disc Degeneration By Interaction With Tnf-Α Through The JAK-Stat Signaling Pathway
- IL-25 improves IgA levels during parenteral nutrition through the JAK-STAT pathway
- IL-27 inhibits IFN-γ induced autophagy by concomitant induction of JAK/PI3 K/Akt/mTOR cascade and up-regulation of Mcl-1 in Mycobacterium tuberculosis H37Rv …
- Il-27 Promotes Human Placenta–Derived Mesenchymal Stromal Cell Ability To Induce The Generation Of Cd4+ Il-10+ Ifn-Γ+ T Cells Via The Jak/Stat Pathway In The …
- IL28B inhibits hepatitis C virus replication through the JAK–STAT pathway
- Il-34 Regulates Il-6 And Il-8 Production In Human Lung Fibroblasts Via Mapk, Pi3K-Akt, JAK And Nf-Κb Signaling Pathways
- IL-4 and IL-13 upregulate arginase I expression by cAMP and Jak/Stat6 pathways in vascular smooth muscle cells
- IL-4 induced MUC4 enhancement in respiratory epithelial cells in vitro is mediated through JAK-3 selective signaling
- IL-4 induces columnar-like differentiation of esophageal squamous epithelium through JAK/PI3K pathway: possible role in pathogenesis of Barrett’s esophagus
- IL-4, JAK-STAT signaling, and pain
- IL-4/IL-13 signaling beyond Jak/Stat
- IL-4-dependent CD86 expression requires Jak/Stat6 activation and is negatively regulated by PKCδ
- IL-6 activated Jak/Stat3 pathway and sensitivity to Hsp90 inhibitors in multiple myeloma
- IL‐6 and soluble IL‐6 receptor stimulate the production of MMPs and their inhibitors via JAK—STAT and ERK—MAPK signalling in human chondrocytes
- Il-6 Improves Myogenesis In Long-Term Skeletal Muscle Atrophy Via The Jak/Stat3 Signalling Pathway
- IL-6 inhibits apoptosis of human myeloma cell line XG-7 through activation of Jak/Stat pathway and up-regulation of Mcl-1.
- Il-6 Mediated Jak/Stat3 Signaling Pathway In Cancer Patients With Cachexia.
- Il-6 Mediates The Signal Pathway Of JAK-Stat3-Vegf-C Promoting Growth, Invasion And Lymphangiogenesis In Gastric Cancer
- IL-6 plays an obligatory role in late preconditioning via JAK–STAT signaling and upregulation of iNOS and COX-2
- IL-6 Promotes cell proliferation and antiapoptosis through activation of the Jak/Stat3 pathway in patients with NK/T-cell lymphoma and correlates with poor …
- IL-6 promotes cell proliferation via Jak/Stat independent pathway in mouse hepatocellular carcinoma cells.
- Il-6 Promotes Fsh-Induced Vegf Expression Through Jak/Stat3 Signaling Pathway In Bovine Granulosa Cells
- IL-6 promotes head and neck tumor metastasis by inducing epithelial–mesenchymal transition via the JAK-STAT3-SNAIL signaling pathway
- IL-6 regulates Mcl-1L expression through the JAK/PI3K/Akt/CREB signaling pathway in hepatocytes: implication of an anti-apoptotic role during liver …
- Il-6/Jak/Stat3/Socs3 Signaling Pathway: Potential Therapeutic Effect On Inflammatory Bowel Disease
- IL-6–mediated induction of matrix metalloproteinase-9 is modulated by JAK-dependent IL-10 expression in macrophages
- Il6R Inhibits Viability And Apoptosis Of Pancreatic Beta-Cells In Type 2 Diabetes Mellitus Via Regulation By Mir-22 Of The Jak/Stat Signaling Pathway
- Il-7 Promotes Naïve T Cell Motility And Regulates T Cell-Dendritic Cell Contacts In The Lymph Node Via Jak/Stat Signaling.
- Il7R Expression Predicts T-All Sensitivity To JAK Inhibitors Regardless Of Il7R/Jak/Stat Mutational Status: S131
- Il7R Overexpression In Adult Acute Lymphoblastic Leukemia Is Associated To Jak/Stat Pathway Mutations And Identifies Patients Who Could Benefit From Targeted …
- Il-9 Exhibits Elevated Expression In Osteonecrosis Of Femoral Head Patients And Promotes Cartilage Degradation Through Activation Of JAK-Stat Signaling In Vitro
- Illicium verum extract suppresses IFN-γ-induced ICAM-1 expression via blockade of Jak/Stat pathway in HaCaT human keratinocytes
- Immune Alterations In Psychosis: Focus On The JAK-Stat1 Pathway
- Immune Cell Profiling Of Ifn-Λ Response Shows Pdcs Express Highest Level Of Ifn-Λr1 And Are Directly Responsive Via The JAK-Stat Pathway
- Immune Function Of A Rab‐Related Protein By Modulating The Jak‐Stat Signaling Pathway In The Silkworm, Bombyx Mori
- Immunoexpression Analysis Of Selected Jak/Stat Pathway Molecules In Patients With Non-Small-Cell Lung Cancer.
- Immunogenic effects of recombinant interferon-beta therapy disrupt the Jak/Stat pathway in primary immune cells from patients with multiple sclerosis
- Immunogenic Effects Of Recombinant Interferon-Beta Therapy Disrupt The Jak/Stat Pathway In Primary Immune Cells…
- Immunohistochemical Analysis Of The Expression Of Cellular Transcription Nfκb (P65), Ap-1 (C-Fos And C-Jun), And Jak/Stat In Leprosy
- Immunohistochemical detection of phosphorylated JAK-2 and STAT-5 proteins and correlation with erythropoietin receptor (EpoR) expression status in human brain …
- Immunohistochemical Expression Of JAK-P, Stat3 & Bcl-2 In Oral Squamous Cell Carcinoma With And Without Lymph Node Metastasis And In Verrucous …
- Immunolocalisation of the janus kinases (JAK)—signal transducers and activators of transcription (STAT) pathway in human epidermis
- Immunoprecipitation to determine JAK kinase activation in response to interleukins in ovarian cancer
- Impact and long-term effect of three prescriptions regulating and tonifying lung and kidney on Jak/Stat signaling in rats
- Impact Of Catgut Embedding Intervention On JAK 2-Stat 3 Signaling In Gastric Mucosa Of Chronic Atrophic Gastritis Rats
- Impact of resistance exercise training on interleukin‐6 and Jak/Stat in young men
- Impaired antiviral activity of interferon alpha against hepatitis C virus 2a in Huh-7 cells with a defective JAK-Stat pathway
- Impaired chemokine‐induced migration during T‐cell development in the absence of JAK 3
- Impaired Fetal Muscle Development And JAK-Stat Activation Mark Disease Onset And Progression In A Mouse Model For Merosin-Deficient Congenital Muscular …
- Impaired JAK-STAT signal transduction contributes to growth hormone resistance in chronic uremia
- Impaired renal growth hormone Jak/Stat5 signaling in chronic kidney disease
- Impaired Type I IFN-Induced Jak/Stat
- Impaired type I IFN-induced Jak/Stat signaling in FA-C cells and abnormal CD4+ Th cell subsets in Fancc−/− mice
- JAK-STAT_pathway_in_gliomagenesis_a_target_for_therapy/links/56e2aa0108ae3328e0787747.pdf”>Implication of the JAK-STAT Pathway in Gliomagenesis: A Target for Therapy?
- Importance Of Light In The Treatment Of Vitiligo With JAK-Inhibitors
- Improved probes for detection of V617F mutation in chromosome 9-borne JAK 2 gene linked to conditions of Polycythemia Vera and other myeloproliferative …
- Improving the efficacy of hormonal therapy in MCF-7 breast cancer cells grown in the presence of IGF-I by targeting the MAPK/MEK and Jak/Stat cell survival …
- In Search Of The Greengrocer (JAK Vykládat Zelináře)
- In silico identification of the key components and steps in IFN‐γ induced JAK‐STAT signaling pathway
- In the article entitled “marelle Acts Downstream of the Drosophila HOP/JAK Kinase and Encodes a Protein Similar to the Mammalian STATs” by XS Hou, MB Melnick …
- In Vitro And In Vivo Effects Of Jak2 Inhibition In Chronic Myelomonocytic Leukemia
- In vitro effects of the novel JAK II inhibitor BSK805 in BCR-ABL and JAK II V617F-positive cell lines.
- In Vitro Pharmacological Effects Of Peficitinib On Lymphocyte Activation: A Potential Treatment For Systemic Sclerosis With JAK Inhibitors
- In vitro shoot initiation of Artocarpus heterophyllus Lam.(JAK Fruit) Effect of the explant type and the season of explant collection
- In Vivo And In Vitro Effects Of Microrna‐221 On Hepatocellular Carcinoma Development And Progression Through The Jak–Stat3 Signaling Pathway By Targeting …
- In vivo characterization of two novel regulators of the Jak/Stat pathway in Drosophila melanogaster
- In vivo localization and characterization of functional ciliary neurotrophic factor receptors which utilize JAK-STAT signaling
- In vivo monitoring of Jak/Stat and PI3K/mTOR signal transduction inhibition in pediatric CRLF2-rearranged acute lymphoblastic leukemia (ALL).
- In Vivo Study Of Rna Interference, The Jak/Stat Pathway And Their Cross-Talk In Bombus Terrestris Upon Viral Infections
- Inactivation of SSI-1, a Jak/Stat inhibitor, in human hepatocellular carcinomas, as revealed by two-dimensional electrophoresis
- Inadequacy of the Jak/Stat Signal Transduction Pathway to Mediate Episodic Growth Hormone-dependent Regulation of Hepatic CYP2C11
- Increased Expression Of Hepcidin And Associated Upregulation Of Jak/Stat3 Signaling In Human Gastric Cancer
- Increased Incidence Of Cytomegalovirus Coinfection In Hcv-Infected Patients With Late Liver Fibrosis Is Associated With Dysregulation Of JAK-Stat Pathway
- Increasing Jak/Stat Signaling Function Of Infant Cd4+ T Cells During The First Year Of Life
- Indirubin inhibits tumor growth by antitumor angiogenesis via blocking VEGFR2‐mediated Jak/Stat3 signaling in endothelial cell
- Indirubin-3′-monoxime inhibits rat vascular smooth muscle cell proliferation induced by plateled-derived growth factor via the Jak/Stat-pathway
- Indoleamine 2, 3-dioxygenase, an immunomodulatory protein, is suppressed by (−)-epigallocatechin-3-gallate via blocking of γ-interferon-induced JAK-PKC-δ-STAT1 …
- Inducers of oxidative stress block ciliary neurotrophic factor activation of Jak/Stat signaling in neurons
- Induction of apoptosis in large granular lymphocyte (Lgl) Leukemia by JAK tyrosine kinase inhibitor AG-490: Role of STAT3-regulated MCL-1
- Induction of BAFF expression by IFN‐γ via Jak/Stat signaling pathways in human intestinal epithelial cells
- Induction of erythroid proliferation and differentiation by a trophoblast-specific cytokine involves activation of the Jak/Stat pathway
- Induction of MMP-9 release from human dermal fibroblasts by thrombin: involvement of Jak/Stat3 signaling pathway in MMP-9 release
- Induction of TRIM22 by IFN-γ Involves JAK and PC-PLC/PKC, but Not MAPKs and pI3K/Akt/mTOR Pathways
- Infection-induced IL-10 and JAK-STAT: A review of the molecular circuitry controlling immune hyperactivity in response to pathogenic microbes
- Inflammation Potently Suppresses Abca1-Mediated Cholesterol Efflux From Macrophages, And Not Adipocytes, Via Activation Of Jak/Stat Pathway
- Inflammatory And JAK-Stat Pathways As Shared Molecular Targets For Anca-Associated Vasculitis And Nephrotic Syndrome
- Inflammatory cytokines regulate microRNA-155 expression in human retinal pigment epithelial cells by activating Jak/Stat pathway
- Inflammatory Signaling In Liver Cells: Cross-Regulation Of The Il-6/Jak/Stat3 Pathway And Micrornas
- Influence Of Mesenchymal Stem Cells On Respiratory Distress Syndrome In Newborn Swines Via The JAK-Stat Signaling Pathway.
- Influence of moxibustion on JAK-STAT signal transduction pathways of synovial cells in rheumatoid arthritis rabbits
- Influence Of Roflumilast On Sepsis Mice Through The Jak/Stat Signaling Pathway
- Influenza A virus abrogates IFN‐γ response in respiratory epithelial cells by disruption of the Jak/Stat pathway
- Inhaled Janus Kinase (Jak) Inhibitors For The Treatment Of Asthma
- Inhibited PTHLH downstream leukocyte adhesion-mediated protein amino acid N-linked glycosylation coupling Notch and JAK–STAT cascade to iron–sulfur cluster …
- Inhibition Of Atm Reverses Emt And Decreases Metastatic Potential Of Cisplatin-Resistant Lung Cancer Cells Through Jak/Stat3/Pd-L1 Pathway
- Inhibition of constitutively active JAK-Stat pathway suppresses cell growth of human T-cell leukemia virus type 1-infected T-cell lines and primary adult T-cell leukemia …
- Inhibition of constitutively active JAK-Stat pathway suppresses cell growth of human T-cell leukemia virus type 1-infected T-cell lines and primary adult T-cell …
- Inhibition of cytokine production and interference in IL-2 receptor-mediated JAK-Stat signaling by the hydroxylamine metabolite of sulfamethoxazole
- Inhibition of IL-2-induced JAK-STAT signaling by glucocorticoids
- Inhibition Of IL-6 Stimulated JAK-Stat Signaling By Human Metapneumovirus And Respiratory Syncytial Virus
- Inhibition Of Il‐6‐Jak/Stat3 Signaling In Castration‐Resistant Prostate Cancer Cells Enhances The Nk Cell‐Mediated Cytotoxicity Via Alteration Of Pd‐L1/Nkg2D Ligand …
- Inhibition of Interferon (IFN) γ-induced JAK-STAT1 Activation in Microglia by Vasoactive Intestinal Peptide INHIBITORY EFFECT ON CD40, IFN-INDUCED PROTEIN …
- Inhibition of interferon-stimulated JAK-STAT signaling by a tick-borne flavivirus and identification of NS5 as an interferon antagonist
- Inhibition Of Interleukin-3-And Interferon-Α-Induced Jak/Stat Signaling By The Synthetic Α-X-2′, 3, 4, 4′-Tetramethoxychalcones Α-Br-Tmc And Α-Cf3-Tmc
- Inhibition of JAK kinase activity enhances Fas-mediated apoptosis but reduces cytotoxic activity of topoisomerase II inhibitors in U266 myeloma cells
- Inhibition of Jak/Stat pathway in airway epithelium as a potential targeted therapy of asthma
- Inhibition of Jak/Stat signaling ameliorates mice experimental nephrotic syndrome
- Inhibition of Jak/Stat signaling pathway prevents high-glucose-induced increase in endothelin-1 synthesis in human endothelial cells
- Inhibition of Jak/Stat signaling synergizes with CTLA4-Ig to promote transplant acceptance (IRC2P. 454)
- Inhibition of Jak/Stat Signalling: A Novel Therapy for Steroid Resistant Asthma?.
- Inhibition Of JAK-Stat And Nf-Κb Signalling Systems Could Be A Novel Therapeutic Target Against Insulin Resistance And Type 2 Diabetes
- Inhibition Of JAK-Stat Erk/Mapk And Glycogen Synthase Kinase-3 Induces A Change In Gene Expression Profile Of Bovine Induced Pluripotent Stem Cells
- Inhibition of JAK-STAT pathway as a therapeutic option for myelofibrosis associated pulmonary hypertension
- Inhibition of JAK–STAT signaling by TG101348: a novel mechanism for inhibition of KITD816V-dependent growth in mast cell leukemia cells
- Inhibition of JAK-STAT signaling stimulates adult satellite cell function
- Inhibition Of JAK-Stat Signaling Suppresses Pathogenic Immune Responses In Medium And Large Vessel Vasculitis
- Inhibition Of JAK-Stat Signaling With Baricitinib Reduces Inflammation And Improves Cellular Homeostasis In Progeria Cells
- Inhibition of JAK-STAT3 pathway enhances bufalin-induced apoptosis in colon cancer SW620 cells
- Inhibition Of Microrna‐132 Attenuates Inflammatory Response And Detrusor Fibrosis In Rats With Interstitial Cystitis Via The Jak‐Stat Signaling Pathway
- Inhibition Of Microrna‑155 Relieves Sepsis‑Induced Liver Injury Through Inactivating The Jak/Stat Pathway
- Inhibition Of Mtorc1/C2 Signaling Improves Anti-Leukemia Efficacy Of Jak/Stat Blockade In Crlf2 Rearranged And/Or JAK Driven Philadelphia Chromosome …
- Inhibition Of Pdgf-Bb-Induced Proliferation And Migration In Vsmcs By Proanthocyanidin A2: Involvement Of Kdr And JAK-2/Stat-3/Cpla2 Signaling …
- Inhibition Of The Invasion Of Human Glioblastoma U87 Cell Line By Ruxolitinib: A Molecular Player Of Mir-17 And Mir-20A Regulating Jak/Stat Pathway.
- Inhibition Of The Jak/Stat And Bcl-2 Pathways Enhances Anti-Tumor Effects In An In Vitro Model Of T Cell Acute Lymphoblastic Leu
- Inhibition Of The Jak/Stat Pathway By Ruxolitinib Ameliorates Thioacetamide-Induced Hepatotoxicity
- Inhibition of the Jak/Stat pathway in Waldenstrom’s Macroglobulinemia
- Inhibition of the Jak/Stat pathway with ruxolitinib overcomes cisplatin resistance in non-small-cell lung cancer NSCLC
- Inhibition Of The Jak/Stat Signaling Pathway As a Novel Therapy In CD8+ T-Large Granular Lymphocyte Leukemia
- Inhibition Of The Jak/Stat Signaling Pathway In Regulatory T Cells Reveals A Very Dynamic Regulation Of Foxp3 Expression
- Inhibition of the Jak/Stat signaling pathway prevents the high glucose-induced increase in TGF-β and fibronectin synthesis in mesangial cells
- Inhibition of the JAK-2/STAT3 signaling pathway impedes the migratory and invasive potential of human glioblastoma cells
- Inhibition of the JAK-STAT pathway prevents CNTF-mediated survival of axotomized oxytocinergic magnocellular neurons in organotypic cultures of the rat supraoptic …
- Inhibition of the JAK-STAT3 pathway by andrographolide enhances chemosensitivity of cancer cells to doxorubicin
- Inhibition of the JAK-STAT3 signaling pathway by ganoderic acid A enhances chemosensitivity of HepG2 cells to cisplatin
- Inhibition Of The JAK-Stat3-Mcl-1 Axis By Combining Ruxolitinib With S63845 Completely Prevents Plasmacytoma Growth In The Gp130-Regulated Ina-6 Xenograft …
- Inhibition of the Janus (JAK)/Signal Transducers of Activated Transcription (STAT) Pathway prevents the Development of Angiotensin II-induced Hypertension
- Inhibition of the Src and JAK kinases protects against lipopolysaccharide-induced acute lung injury
- Inhibition of tumour necrosis factor and IL-17 production by leflunomide involves the Jak/Stat pathway
- Inhibition Of Tyrosine Kinase Signaling By Tyrphostin Ag126 Downregulates The Il-21/Il-21R And Jak/Stat Pathway In The Btbr Mouse Model Of Autism
- Inhibition On JAK-Stat3 Signaling Transduction Cascade Is Taken By Bioactive Peptide Alpha-S2 Casein Protein From Goat Ethawah Breed Milk
- Inhibitor‐Based Affinity Probes For The Investigation Of JAK Signaling Pathways
- Inhibitors of JAK for the treatment of rheumatoid arthritis: rationale and clinical data
- Inhibitors Of JAK-Family Kinases: An Update On The Patent Literature 2013-2015, Part 1
- Inhibitors Of JAK-Family Kinases: An Update On The Patent Literature 2013-2015, Part 2
- Inhibitors Of The Jak/Stat Pathway, With A Focus On Ruxolitinib And Similar Agents
- Inhibitors of the Janus Kinase–Signal Transducers and Activators of Transcription (Jak/Stat) Signaling Pathway
- INHIBITORY EFFECT OF TITANIUM ON IL-10 MEDIATED Jak/Stat SIGNAL TRANSDUCTION PATHWAY
- Initiation and maintenance of CNTF–Jak/Stat signaling in neurons is blocked by protein tyrosine phosphatase inhibitors
- Innate Resistance Of Pd-1 Blockade Through Loss Of Function Mutations In JAK Resulting In Inability To Express Pd-L1 Upon Interferon Exposure
- In-Silico Study Of Bioactive Compounds Of Natural Materials As A JAK-Signal Transducer And Activator Of Transcription …
- Instructing naïve pluripotency: Jak/Stat3 and Nanog in reprogramming
- Insulin Receptor Substrate-4 Interacts With Ubiquitin-Specific Protease 18 To Activate The Jak/Stat Signaling Pathway
- Insulin resistance-inducing cytokines differentially regulate SOCS mRNA expression via growth factor-and Jak/Stat-signaling pathways in 3T3-L1 adipocytes
- Insulin-like growth factor-I induces MAPK and Jak/Stat signaling and protects breast cancer cells from hormonally-induced cytostasis and cell death
- Insulin‐like growth factor‐I receptor signal transduction and the Janus Kinase/Signal Transducer and Activator of Transcription (JAK‐STAT) pathway
- Intact JAK–STAT signaling pathway is a prerequisite for STAT1 to reinforce the expression of RIG-G gene
- Inteferons pen the JAK–STAT pathway
- Integrated Genomic Analysis Identifies Deregulated Jak/Stat-Myc-Biosynthesis Axis In Aggressive Nk-Cell Leukemia
- Integrating Immunologic Signaling Networks: The Jak/Stat Pathway In Colitis And Colitis-Associated Cancer
- Integrating non-coding RNAs in JAK-STAT regulatory networks
- Interaction between leptin and insulin signaling pathways differentially affects JAK-STAT and PI 3-kinase-mediated signaling in rat liver
- Interaction of JAK with steroid receptor function
- Interactions Between Eyes Absent And Jak/Stat Signaling During Drosophila Development
- Interdependence Of JAK-Stat And Mapk Signaling Pathways During Egf-Mediated Htr-8/Svneo Cell Invasion
- Interest Free Co-operatives: A study of JAK Members Bank–Sweden
- Interferon Alpha On Oral Squamous Cell Cancer JAK Signal Transduction And Transcriptional Activation Suppressor Cytokine Signal Pathways Of Gene Expression
- Interferon tau regulates PGF2α release from the ovine endometrial epithelial cells via activation of novel JAK/EGFR/ERK/EGR-1 pathways
- INTERFERON TAU REGULATES PROSTAGLANDIN F2A RELEASE THROUGH JAK/SRC/EGFR/ERK1/2 PATHWAYS IN OVINE ENDOMETRIAL EPITHELIAL CELLS
- Interferon γ attenuates insulin signaling, lipid storage, and differentiation in human adipocytes via activation of the Jak/Stat pathway
- Interferon-Alpha Inhibits Adipogenesis Via Regulation Of Jak/Stat1 Signaling
- Interferon-alpha upregulates thymidine phosphorylase expression via JAK-STAT transcriptional activation and mRNA stabilization in human hepatocellular carcinoma …
- Interferon–Differentially Regulates Transforming Growth Factor–ß1 and TGF–ß2 Expression in Human Retinal Pigment Epithelial Cells Through JAK Dependent …
- Interferon-Gamma Induces Pd-L1 Expression Via Ifngr-JAK-Stat Pathway In Ovarian Cancer
- Interferons activate the p42/44 mitogen-activated protein kinase and JAK-STAT (Janus kinase-signal transducer and activator transcription factor) signalling pathways …
- Interferons upregulate thymidine phosphorylase expression via JAK-STAT-dependent transcriptional activation and mRNA stabilization in human glioblastoma cells
- Interferon-α induces G1 cell-cycle arrest in renal cell carcinoma cells via activation of JAK-Stat signaling
- Interferon‐Α Induces Marked Alterations In Circulating Regulatory T Cells, Nk Cell Subsets, And Dendritic Cells In Patients With JAK 2V617F‐Positive Essential …
- Interferon‐β induces apoptosis in human SH‐SY5Y neuroblastoma cells through activation of JAK–STAT signaling and down‐regulation of PI3K/Akt pathway
- Interferon-γ biphasically regulates angiotensinogen expression via a JAK-STAT pathway and suppressor of cytokine signaling 1 (SOCS1) in renal proximal tubular …
- Interferon‐γ differentially regulates TGF‐β1 and TGF‐β2 expression in human retinal pigment epithelial cells through JAK‐STAT pathway
- Interferon-γ enhances superoxide production in human mesangial cells via the JAK–STAT pathway
- Interferon-γ Induces AT2 Receptor Expression in Fibroblasts by Jak/Stat Pathway and Interferon Regulatory Factor-1
- Interferon-γ inhibits cellular proliferation and ACTH production in corticotroph tumor cells through a novel JAK-STAT1/NF-κB inhibitory signalling pathway
- Interferon-Γ Stimulates Human Follicular Dendritic Cell-Like Cells To Produce Prostaglandins Via The JAK-Stat Pathway
- Interferon-γ-JAK-Stat signaling in pulmonary lymphangioleiomyomatosis and renal angiomyolipoma: a potential therapeutic target
- Interleukin 9 Prevents Immune Thrombocytopenia In Mice Via Jak/Stat5 Signaling
- Interleukin-10 Inhibits Neuroinflammation-Mediated Apoptosis Of Ventral Mesencephalic Neurons Via JAK-Stat3 Pathway
- Interleukin‑10 Promotes Proliferation And Migration, And Inhibits Tendon Differentiation Via The Jak/Stat3 Pathway In Tendon‑Derived Stem Cells In Vitro
- Interleukin-11 Induces The Expression Of Matrix Metalloproteinase 13 In Gastric Cancer Sch Cells Partly Via The Pi3K-Akt And JAK-Stat3 Pathways
- Interleukin-11 induces the expression of matrix metalloproteinase 13 in gastric cancer SCH cells partly via the PI3K-AKT and JAK-STAT3 pathways Retraction in …
- Interleukin-12-anchored exosomes increase cytotoxicity of T lymphocytes by reversing the Jak/Stat pathway impaired by tumor-derived exosomes
- Interleukin-17 Upregulates Vascular Endothelial Growth Factor By Activating The Jak/Stat Pathway In Nucleus Pulposus Cells
- Interleukin-1β can mediate growth arrest and differentiation via the leukemia inhibitory factor/Jak/Stat pathway in medullary thyroid carcinoma cells
- Interleukin-22 (IL-22) activates the Jak/Stat, ERK, JNK, and p38 MAP kinase pathways in a rat hepatoma cell line Pathways that are shared with and distinct from IL …
- Interleukin-22 Promotes Triple Negative Breast Cancer Cells Migration And Paclitaxel Resistance Through JAK-Stat3/Mapks/Akt Signaling Pathways
- Interleukin-29 binds to melanoma cells inducing JAK-STAT signal transduction and apoptosis
- Interleukin-4 mediated changes in growth and glucose metabolismin naïve B lymphocytes: A role for the Jak/Stat pathway
- Interleukin-6 Activates The Sodium Chloride Cotransporter Via The Janus Kinase (Jak)/Signal Transducer And Activator Of Signaling (Stat)
- Interleukin-6 Activation of AMPK Involves Both JAK-Stat and Cyclic AMP-Mediated Signaling.
- Interleukin-6 Attenuates Serotonin 2A Receptor Signaling By Activating The JAK-Stat Pathway
- Interleukin-6 induced basic fibroblast growth factor-dependent angiogenesis in basal cell carcinoma cell line via Jak/Stat3 and PI3-kinase/Akt pathways
- Interleukin-6 Promotes Proliferation But Inhibits Tenogenic Differentiation Via The Janus Kinase/Signal Transducers And Activators Of Transcription 3 (Jak/Stat3) Pathway In Tendon-Derived Stem Cells
- Interleukin-6 Reduces Nmdar-Mediated Cytosolic Ca2+ Overload And Neuronal Death Via Jak/Can Signaling
- Interleukin-6 Requires JAK To Stimulate Inner Cell Mass Expansion In Bovine Embryos
- Interleukin-6 silences y gene expression via the Jak/Stat signal transduction pathway
- Interleukin‐6‐induced satellite cell proliferation is regulated by induction of the JAK 2/STAT 3 signalling pathway through cyclin D1 targeting
- Interleukin-6-Mediated Functional Upregulation Of Trpv1 Receptors In Dorsal Root Ganglion Neurons Through The Activation Of Jak/Pi3K Signaling Pathway: Roles In The …
- Interleukin‐7 promotes the survival of human CD4+ effector/memory T cells by up‐regulating Bcl‐2 proteins and activating the Jak/Stat signalling pathway
- Interleukin‐7 stimulates secretion of S100A4 by activating the Jak/Stat signaling pathway in human articular chondrocytes
- Interplay between the cardiac renin angiotensin system and JAK-STAT signaling: role in cardiac hypertrophy, ischemia/reperfusion dysfunction, and heart failure
- Interpretation of the UPD/Jak/Stat morphogen gradient in Drosophila follicle cells
- Intervention Effects Of Compound Houttuyniae Herba To Diabetic Renal Damage Based On Socs-Jak/Stat Negative Feedback Regulation
- Intestinal Vitamin D Receptor Protects Mice From Dysbiosis Via Modulating Jak/Stat Pathway In Tumorigenesis
- Intra-amygdala microinfusion of IL-6 impairs the auditory fear conditioning of rats via Jak/Stat activation
- Intracellular expression of IRF9 Stat fusion protein overcomes the defective JAK-Stat signaling and inhibits HCV RNA replication
- Intracellular interferon triggers Jak/Stat signaling cascade and induces p53-dependent antiviral protection
- Intracellular proteins and mechanisms involved in the control of gp130/Jak/Stat cytokine signaling
- Intracellular Tat of human immunodeficiency virus type 1 activates lytic cycle replication of Kaposi’s sarcoma-associated herpesvirus: role of Jak/Stat signaling
- Intrahepatic synthesis of tumor necrosis factor-α related to cardiac surgery is inhibited by interleukin-10 via the Janus kinase (Jak)/signal transducers and activator of …
- Intranasal Administration of CNTF and Erythropoietin Activate the Jak/Stat Survival Pathway in Rat Retina
- Intraspinal Administration Of Interleukin-7 Promotes Neuronal Apoptosis And Limits Functional Recovery Through Jak/Stat5 Pathway Following Spinal Cord Injury
- Introduction to JAK: ideology, structure and saving’s and loan’s system www. jak. se
- Investigating Role Of The Jak/Stat Pathway In Cardiac Hypertrophy Induced By The Interval And Continuous Trainings In Adult Male Rats
- Investigating the differential properties of the Drosophila Jak/Stat pathway ligands
- Investigating The Functional Consequences Of Jak/Stat Mutations In SéZary Syndrome
- Investigating The Role Of Jak/Stat Pathway On Dasatinib-Induced Apoptosis For Cml Cell Model K562
- Investigating The Role Of Jak/Stat Pathway Upon Dasatinib Induced Apoptosis For Cml Cell Model K562
- Investigating the role of the Jak/Stat and MAPK Pathways in Ischaemia/Reperfusion Injury and Inflammation
- Investigating The Role Of The Jak/Stat Pathway And Dna Damage Response (Ddr) Pathways In Testicular Ischemia Reperfusion Injury
- Investigation of Jak/Stat signaling in human skeletal muscle
- Investigation of leaves and saw dust of JAK tree as potential colouring agent for textile substrates
- Investigation Of Selective JAK 1 Inhibitor Gsk 2586184 For The Treatment Of Psoriasis In A Randomized Placebo‐Controlled Phase Ii A Study
- Involvement of a Jak/Stat pathway inhibitor: cytokine inducible SH2 containing protein in breast cancer
- Involvement of activation of Janus kinase (JAK) 2 in the mechanisms utilized by Norepinephrine (NE) to cause hypertension.
- Involvement of caveolin-1 in the Jak–Stat signaling pathway and infectious spleen and kidney necrosis virus infection in mandarin fish (Siniperca chuatsi)
- Involvement of Jak/Stat (Janus kinase/signal transducer and activator of transcription) in the thyrotropin signaling pathway
- Involvement Of Jak/Stat Signaling And A Basement Membrane-Associated Protein During Air Sac Primordium Development In Drosophila Melanogaster
- Involvement of Jak/Stat signaling in the effect of cornel iridoid glycoside on experimental autoimmune encephalomyelitis amelioration in rats
- Involvement of Jak/Stat signaling in the pathogenesis of inflammatory bowel disease
- Involvement of JAK-STAT Signaling in CTGF Promoted Lung Fibroblast-myofibroblast Transdifferentiation
- Involvement of JAK-STAT signaling/function after cyclophosphamide-induced bladder inflammation in female rats
- Involvement of the JAK‐STAT pathway and SOCS3 in the regulation of adiponectin‐generated reactive oxygen species in murine macrophage RAW 264 cells
- Involvement Of The Jak‐Stat Pathway In Collagen Regulation Of Decidual Nk Cells
- Involvement Of The JAK-Stat Pathway In The Pathogenesis Of Inflammatory Bowel Diseases
- Involvement of the JAK-STAT3 pathway in a lipopolysaccharide-induced rat model of airway inflammation
- Involvement Of Transcription Factor Oct-1 In The Regulation Of Jak–Stat Signaling Pathway In Cells Of Burkitt Lymphoma
- Ion beams and channelling: the early days with JAK Kelly
- Iron Uptake Via Dmt1 Integrates Cell Cycle With JAK-Stat3 Signaling To Promote Colorectal Tumorigenesis
- Is Allogeneic Stem Cell Transplantation For Myelofibrosis Still Indicated At The Time Of Molecular Markers And JAK Inhibitors Era?
- Is It Time To Revisit Contraindications To Organ Donation From Donors With A Jak‐2 Mutation? Safe Use Of A Liver Allograft From A Donor With Essential Thrombocythaemia
- Is Platelet Aggregation a Useful Investigation in Assessing the Risk of Thrombosis in Patients With JAK-Positive Chronic Myeloproliferative Disorders? Brief Report: A …
- Is there a role for JAK inhibitors in BCR-ABL1-negative myeloproliferative neoplasms other than myelofibrosis?
- Isg12A Inhibits Hcv Replication And Potentiates The Anti-Hcv Activity Of Ifn-Α Through Activation Of The Jak/Stat Signaling Pathway Independent Of Autophagy And …
- Isoform Promotes Tumour Invasion And Metastasis Via Interleukin-6 Activation Of JAK-Stat And Rhoa-Rock Signalling
- Isolated GHD: investigation and implication of Jak/Stat related genes before and after rhGH treatment
- ITF increases the transcriptional activity of ITF promoter via the JAK-STAT3 signal transduction pathway
- Itf Promotes Migration Of Intestinal Epithelial Cells Through Crosstalk Between The Erk And Jak/Stat3 Pathways
- ITF2357 inhibits corneal fibrosis and inflammation via Jak/Stat3 signaling pathway
- ITF2357 regulates IL-10 via Jak/Stat signaling pathway to attenuate inflammation and fibrosis
- Itk Signaling Differentiates Gvt And Gvhd After Allogeneic Bone Marrow Transplantation By Regulating Irf-4, Jak/Stat And Eomesodermin Expression
- Ixodes scapularis JAK-STAT Pathway Regulates Tick Antimicrobial Peptides, Thereby Controlling the Agent of Human Granulocytic Anaplasmosis
- Jagged1 regulates the activation of astrocytes via modulation of NFκB and Jak/Stat/SOCS pathways
- JAK 1/2 Blockade In Mda5 Gain-Of-Function
- JAK 2 And Stat Proteins; A Mini Review
- JAK 2 Mutation In Recurrent Fetal Loss
- JAK 2 V 617 F mutation and 46/1 haplotype in C hinese B udd‐C hiari syndrome patients
- JAK 2 V617 Mutation With Myeloid Hyperplasia And Blast Formation In Idiopathic Myelofibrosis
- JAK 2 V617F Mutation Can Be Reliably Detected In Serum Using Droplet Digital Pcr
- JAK 2/STAT 3 activation by melatonin attenuates the mitochondrial oxidative damage induced by myocardial ischemia/reperfusion injury
- JAK 2‐Positive Cutaneous Myelofibrosis Presenting As Sclerosing Extramedullary Hematopoietic Tumors On The Scalp: Case Presentation And Review Of The Literature
- JAK 2‐related pathway induces acquired erlotinib resistance in lung cancer cells harboring an epidermal growth factor receptor‐activating mutation
- JAK 2V617F mutation: frequency and relation to clinical and laboratory features of BCR-ABL negative myeloproliferative diseases
- JAK Academy In Rheumatoid Arthritis (Ra)
- JAK and Jumonji: Deadly Playmates
- JAK and MPL mutations in myeloid malignancies
- JAK and Src tyrosine kinase signaling in asthma
- JAK And Stat Members In Channel Catfish: Identification, Phylogenetic Analysis And Expression Profiling After Edwardsiella Ictaluri Infection
- JAK And Stat Members Of Yellow Catfish Pelteobagrus Fulvidraco And Their Roles In Leptin Affecting Lipid Metabolism
- JAK and STAT proteins are expressed and activated by IFN‐γ in rat pancreatic acinar cells
- JAK and STAT signaling molecules in immunoregulation and immune-mediated disease
- JAK and Syk: Emerging their relevance to the treatment of inflammatory diseases
- JAK Efficacy In Crohn’S Disease
- JAK Family Members: Molecular Cloning, Expression Profiles And Their Roles In Leptin Influencing Lipid Metabolism In Synechogobius Hasta
- JAK family of kinases in cancer
- JAK Family of Tyrosine Kinases: Its Functions and Alterations in Human Cancer
- JAK Goes Nuclear
- JAK inhibitors AG-490 and WHI-P154 decrease IFN-γ-induced iNOS expression and NO production in macrophages
- JAK Inhibitors Alter Nk Cell Functions And May Impair Immunosurveillance Against Lymphomagenesis
- JAK Inhibitors And Alopecia Areata
- JAK Inhibitors And Alopecia Areata Rwanda And Revisionist History
- JAK Inhibitors And Myelofibrosis, Einstein And Ruxolitinib
- JAK inhibitors and other novel agents in myeloproliferative neoplasms: are we hitting the target?
- JAK Inhibitors And Oxidative Stress Control
- JAK Inhibitors And Risk Of B-Cell Lymphomas
- JAK Inhibitors As New Drugs For Treatment Of Paclitaxel-Resistant Anaplastic Thyroid Cancer
- JAK Inhibitors As Therapy For Myelofibrosis
- JAK Inhibitors For Alopecia Areata: A Systematic Review And Meta‐Analysis
- JAK Inhibitors For Atopic Dermatitis: An Update
- JAK Inhibitors For Refractory Lymphoma.
- JAK Inhibitors For Rheumatoid Arthritis
- JAK Inhibitors For The Treatment Of Autoimmune And Inflammatory Diseases
- JAK Inhibitors For The Treatment Of Myeloproliferative Neoplasms And Other Disorders
- JAK Inhibitors For Treatment Of Alopecia Areata
- JAK Inhibitors In 2019, Synthetic Review In 10 Points
- JAK Inhibitors In Alopecia Areata
- JAK Inhibitors In Autoinflammation
- JAK Inhibitors In Dermatology: The Promise Of A New Drug Class
- JAK inhibitors in myeloproliferative neoplasms: rationale, current data and perspective
- JAK inhibitors in psoriasis: a promising new treatment modality.
- JAK Inhibitors In Refractory Juvenile Idiopathic Arthritis-Associated Uveitis
- JAK Inhibitors In Rheumatology: Implications For Paediatric Syndromes?
- JAK Inhibitors In The Management Of Rheumatoid Arthritis
- JAK Inhibitors In The Treatment Algorithm Of Rheumatoid Arthritis: A Review
- JAK Inhibitors Modulate Production Of Replication-Competent Zika Virus In Human Hofbauer, Trophoblasts, And Neuroblastoma Cells
- JAK-inhibitors-offer-hope-vitiligo-patients”>JAK Inhibitors Offer Hope For Vitiligo Patients
- JAK inhibitors overcome corticosteroid insensitivity in COPD
- JAK Inhibitors Prior To Allogeneic Stem Cell Transplant For Patients With Myelofibrosis: A Prospective Study
- JAK Inhibitors Suppress Innate Epigenetic Reprogramming: A Promise For Patients With Sjögren’S Syndrome
- JAK inhibitors suppress t (8; 21) fusion protein-induced leukemia
- JAK Inhibitors Taking On Psoriatic Arthritis
- JAK Inhibitors To Suppress Paclitaxel-Resistant Anaplastic Thyroid Cancer Via Il-6 Reduction.
- JAK Inhibitors: A Broadening Approach In Rheumatoid Arthritis.
- JAK inhibitors: beyond spleen and symptoms?
- JAK Inhibitors: Novel Developments In Management Of Ulcerative Colitis
- JAK Inhibitors: Perspectives In Internal Medicine
- JAK inhibitors: pharmacology and clinical activity in chronic myeloprolipherative neoplasms
- JAK inhibitors: treatment efficacy and safety profile in patients with psoriasis
- JAK Kelly-Peerless Head of the School of Physics, UNSW 1985-1989
- JAK Kinase 3 Signaling In Microgliogenesis From The Spinal Nestin+ Progenitors In Both Development And Response To Injury
- JAK kinase activity is required for lymphoma invasion and metastasis
- JAK Kinase Inhibitors as Possible Treatment for Myeloproliferative Disorders and Cancer: Patent Highlight
- JAK Kinase Inhibitors For The Treatment Of Acute Lymphoblastic Leukemia
- JAK Kinase Targeting In Hematologic Malignancies: A Sinuous Pathway From Identification Of Genetic Alterations Towards Clinical Indications
- JAK Kinases (Janus tyrosine kinases)
- JAK kinases are required for the bacterial RNA and poly I: C induced tyrosine phosphorylation of PKR.
- JAK kinases control IL‐5 receptor ubiquitination, degradation, and internalization
- JAK kinases in leukemias, lymphomas, and multiple myeloma
- JAK kinases overexpression promotes in vitro cell transformation
- JAK kinases promote invasiveness in VHL-mediated renal cell carcinoma by a suppressor of cytokine signaling-regulated, HIF-independent mechanism
- JAK klasyfikować?
- JAK Mutations As Escape Mechanisms To Anti–Pd-1 Therapy
- JAK mutations in high-risk childhood acute lymphoblastic leukemia
- JAK Of All Trades: Ruxolitinib As A New Therapeutic Option For Cml Patients
- JAK pathway induction of c‐Myc critical to IL‐5 stimulation of cell proliferation and inhibition of apoptosis
- JAK Polymorphisms: Jack Of All Cytokines, Masters Gvhd?
- JAK pot for Galapagos
- JAK Poznaniacy Oceniają Obecność Germanizmów W Swojej Gwarze?
- JAK protein kinase inhibitors.
- JAK Pseudokinase Domain Variants Highlight Nrtk Vuss Identified With Next-Generation Sequencing In Solid Tumor Patients
- JAK redux: a second look at the regulation and role of JAKs in the heart
- JAK signaling globally counteracts heterochromatic gene silencing
- JAK signaling is somatically required for follicle cell differentiation in Drosophila
- JAK Studenci Matematyki Oceniają Poprawność Dowodu Matematycznego
- JAK the trigger
- JAK tyrosine kinases promote hierarchical activation of Rho and Rap modules of integrin activation
- JAK Uchwalić Nową Konstytucję?
- JAK V617F missense mutation is absent in pancreatic cancer
- JAK-an-oncokinase-in-hematological-cancer”>Jak, An Oncokinase In Hematological Cancer
- Jak/Map Kinase Pathway Activation And Tp53 Mutations In Acute Leukemia With Megakaryocytic And Erythroid Differentiation
- Jak/Stat activation following Src inhibition is mediated by the loss of SOCS2 expression
- Jak/Stat activation induced by Angiotensin II in rats isolated pancreatic islets.
- Jak/Stat and Chromatin Regulation in Drosophila
- Jak/Stat And Hox Dynamic Interactions In An Organogenetic Gene Cascade
- Jak/Stat And Insulin Signaling In Drosophila Muscles Regulate Cellular Immune Responses Against Parasitoid Wasp Infection
- Jak/Stat and PI3K signaling pathways have both common and distinct roles in IL‐7‐mediated activities in human CD8+ T cells
- Jak/Stat and PI3K/AKT pathways form a mutual transactivation loop and afford resistance to oxidative stress-induced apoptosis in cardiomyocytes
- Jak/Stat And Tgf-ß Activation As Potential Adverse Outcome Pathway Of Tio 2 Nps Phototoxicity In Caenorhabditis Elegans
- Jak/Stat and the GATA factor Pannier control hemocyte maturation and differentiation in Drosophila
- Jak/Stat as a novel target for treatment of leukemia
- Jak/Stat autocontrol of ligand-producing cell number through apoptosis
- Jak/Stat Blockade Alters Synovial Bioenergetics, Mitochondrial Function, And Proinflammatory Mediators In Rheumatoid Arthritis
- Jak/Stat but not ERK1/ERK2 pathway mediates interleukin (IL)-6/soluble IL-6R down-regulation of type II collagen, aggrecan core, and link protein transcription in …
- Jak/Stat Controls Organ Size And Fate Specification By Regulating Morphogen Production And Signalling
- Jak/Stat Cytokine Signaling At The Crossroad Of Nk Cell Development And Maturation
- Jak/Stat Disruption Induces Immuno-Deficiency: Rationale For The Development Of JAK Inhibitors As Immunosuppressive Drugs
- Jak/Stat Guarantees Robust Neural Stem Cell Differentiation By Shutting Off Biological Noise
- Jak/Stat inhibition improves macrophage phagocytosis of bacteria
- Jak/Stat Inhibition With Ruxolitinib Enhances Oncolytic Virotherapy In Non-Small Cell Lung Cancer Models
- Jak/Stat Inhibitors And Other Small Molecule Cytokine Antagonists For The Treatment Of Allergic Disease
- Jak/Stat Inhibitors For The Treatment Of Atopic Dermatitis
- Jak/Stat Pathway
- Jak/Stat pathway activation during the development of Drosophila melanogaster
- Jak/Stat Pathway Directed Therapy Of T-Cell Leukemia/Lymphoma: Inspired By Functional And Structural Genomics
- Jak/Stat pathway dysregulation in tumors: a Drosophila perspective
- Jak/Stat Pathway in Drosophila Immunity
- Jak/Stat Pathway In Vitiligo
- Jak/Stat pathway in Waldenström’s macroglobulinemia
- Jak/Stat Pathway Inhibitors And Neurologic Toxicity: Above All Else Do No Harm?
- Jak/Stat Pathway Interacts With Intercellular Cell Adhesion Molecule (Icam) And Vascular Cell Adhesion Molecule (Vcam) While Prostate Cancer Stem Cells …
- Jak/Stat pathway mediates leptin-induced Ⅰ collagen mRNA expression in human hepatic stellate cells
- Jak/Stat pathway mediates retinal ganglion cell survival after acute ocular hypertension but not under normal conditions
- Jak/Stat Pathway Modulates On Porphyromonas Gingivalis Lipopolysaccharide- And Nicotine-Induced Inflammation In Osteoblasts
- Jak/Stat Pathway Modulates On Porphyromonas Gingivalis Lipopolysaccharide-And Nicotine-Induced Inflammation In Osteoblasts
- Jak/Stat Pathway Modulation: Does It Work In Dermatology?
- Jak/Stat Pathway Mutations In T-All, Including The Stat5B N642H Mutation, Are Sensitive To Jak1/Jak3 Inhibitors
- Jak/Stat pathway plays a critical role in the proinflammatory gene expression and apoptosis of RAW264. 7 cells induced by trichothecenes as DON and T-2 toxin
- Jak/Stat Pathway Regulation Of Gabaa Receptor Expression After Differing Severities Of Experimental Tbi
- Jak/Stat pathway signalling in Drosophila melanogaster
- Jak/Stat pathways are not involved in the direct activation of antigen-presenting cells by contact sensitizers
- Jak/Stat pathways in cytokine signaling and myeloproliferative disorders: approaches for targeted therapies
- Jak/Stat Proteins And Their Biological Impact On Nk Cell Development And Function
- Jak/Stat Regulation Of Aspergillus Fumigatus Corneal Infections And Il‐6/23‐Stimulated Neutrophil, Il‐17, Elastase, And Mmp9 Activity
- Jak/Stat signal pathway activation promotes progression and survival of human oesophageal squamous cell carcinoma
- Jak/Stat Signal Transduction: Promising Attractive Targets For Immune, Inflammatory And Hematopoietic Diseases
- Jak/Stat signal transduction: regulators and implication in hematological malignancies
- Jak/Stat signaling and human in vitro myogenesis
- Jak/Stat signaling and invertebrate immune responses
- Jak/Stat signaling coordinates stem cell proliferation and multilineage differentiation in the Drosophila intestinal stem cell lineage
- Jak/Stat Signaling in Cardiac Diseases
- Jak/Stat Signaling In Drosophila Muscles Controls The Cellular Immune Response Against Parasitoid Infection
- Jak/Stat Signaling In Head And Neck Cancer
- Jak/Stat signaling in hematological malignancies
- Jak/Stat signaling in high glucose-induced secretion of transforming growth factor-beta~ 1 and extracellular matrix proteins in mesangial cells
- Jak/Stat Signaling In Insect Innate Immunity
- Jak/Stat Signaling In Regulation Of Innate Lymphoid Cells: The Gods Before The Guardians
- Jak/Stat signaling in renal diseases
- Jak/Stat Signaling In Stem Cells And Regeneration: From Drosophila To Vertebrates
- Jak/Stat signaling in the pathogenesis and treatment of multiple myeloma
- Jak/Stat Signaling Inhibition Enhances Costimulation Blockade And Promotes Transplant Acceptance (Tran1P. 943)
- Jak/Stat signaling is associated with cardiac dysfunction during ischemia and reperfusion
- Jak/Stat Signaling Is Involved In Air Sac Primordium Development Of Drosophila Melanogaster
- Jak/Stat signaling is involved in the inflammatory infiltration of the kidneys in MRL/lpr mice
- Jak/Stat Signaling Is Necessary For Cell Monosis Prior To Epithelial Cell Apoptotic Extrusion
- Jak/Stat signaling is required for hinge growth and patterning in the Drosophila wing disc
- Jak/Stat Signaling Of Natural Killer (Nk) Cells Following Cytokine Stimulation
- Jak/Stat signaling pathway and its relationship with tumor invasion and metastasis [J]
- Jak/Stat Signaling Pathway Gene Expression Is Reduced Following Nelf Knockdown In Gnrh Neurons
- Jak/Stat Signaling Pathway In Artemia Franciscana
- Jak/Stat signaling pathway mediates cytokine‐induced iNOS expression in primary astroglial cell cultures
- Jak/Stat signaling pathway of IL-11 in the protection of intestinal epithelial cells from neutron radiation
- Jak/Stat signaling pathway regulates nox1 and nox4-based NADPH oxidase in human aortic smooth muscle cells
- Jak/Stat Signaling Pathway-Mediated Immune Response In Silkworm (Bombyx Mori) Challenged By Beauveria Bassiana
- Jak/Stat signaling pathways and cancer. Janus kinases/signal transducers and activators of transcription.
- Jak/Stat SIGNALING PATHWAYS IN THE INFLAMMATION RESPONSE DURING LIVER ISCHEMIA/REPERFUSION INJURY: 48
- Jak/Stat Signaling Prevents Excessive Apoptosis To Ensure Maintenance Of The Interfollicular Stalk Critical For Drosophila Oogenesis
- Jak/Stat signaling promotes regional specification by negatively regulating wingless expression in Drosophila
- Jak/Stat Signaling Promotes Regional Specification By Positively Regulating Cyclind Expression In Drosophila
- Jak/Stat Signaling Regulates Gametogenesis And Age-Related Reproductive Maintenance
- Jak/Stat signaling regulates heart precursor diversification in Drosophila
- Jak/Stat Signaling Regulates The Proliferation And Neurogenic Potential Of Müller Glia-Derived Progenitor Cells In The Avian Retina
- Jak/Stat signaling regulates tissue outgrowth and male germline stem cell fate in Drosophila
- Jak/Stat signaling stimulates zebrafish optic nerve regeneration and overcomes the inhibitory actions of Socs3 and Sfpq
- Jak/Stat Signaling: A Tale of Jeeps and Trains
- Jak/Stat Signalling and Haematological Malignancies
- Jak/Stat signalling during normal and pathological myelopoiesis with focus on erythropoiesis and megakaryopoiesis
- Jak/Stat signalling in Drosophila controls cell motility during germ cell migration
- Jak/Stat signalling in Drosophila: insights into conserved regulatory and cellular functions
- Jak/Stat signalling in Huntington’s disease immune cells
- Jak/Stat signalling in niche support cells regulates dpp transcription to control germline stem cell maintenance in the Drosophila ovary
- Jak/Stat Signalling Mediates Cell Survival In Response To Tissue Stress
- Jak/Stat signalling pathway in colorectal cancer: a new biological target with therapeutic implications
- Jak/Stat Signalling Regulates Antimicrobial Activities In Eriocheir Sinensis
- Jak/Stat Signalling, Stem Cell Subversion And Myeloid Malignancies
- Jak/Stat signalling: STAT cannot play with Ken and Barbie
- Jak/Stat signalling–an executable model assembled from molecule-centred modules demonstrating a module-oriented database concept for systems and synthetic …
- Jak/Stat, Raf/MEK/ERK, PI3K/Akt and BCR-ABL in cell cycle progression and leukemogenesis
- Jak/Stat/PKCδ molecular pathways in synovial fluid T lymphocytes reflect the in vivo T helper-17 expansion in psoriatic arthritis
- Jak/Stat/SOCS signaling circuits and associated cytokine-mediated inflammation and hypertrophy in the heart
- Jak/Stat/SOCS‐signaling pathway and colon and rectal cancer
- Jak/Stat: The enigma within the mystery of NMDAR-LTD
- Jak/Stat-1 Signaling Is Required For Reserve Intestinal Stem Cell Activation During Intestinal Regeneration Following Acute Inflammation
- Jak/Stat1 signaling promotes HMGB1 hyperacetylation and nuclear translocation
- Jak/Stat3 And Nf-Κb Signaling Pathways Regulate Cancer Stem-Cell Properties In Anaplastic Thyroid Cancer Cells
- Jak/Stat3 And Smad3 Activities Are Required For The Wound Healing Properties Of Periplaneta Americana Extracts
- Jak/Stat3 pathway inhibition blocks skeletal muscle wasting downstream of IL-6 and in experimental cancer cachexia
- Jak/Stat3 pathway is activated in spinal cord microglia after peripheral nerve injury and contributes to neuropathic pain development in rat
- Jak/Stat3 pathway is involved in survival of neurons in response to insulin-like growth factor and negatively regulated by suppressor of cytokine signaling-3
- Jak/Stat3 Regulated Global Gene Expression Dynamics During Late-Stage Reprogramming Process
- Jak/Stat3 signaling is required for TGF-β-induced epithelial-mesenchymal transition in lung cancer cells
- Jak/Stat3 signaling pathway is involved in α1-AR-mediated cardiac hypertrophy
- Jak/Stat3 Signaling Pathway Mediates Endothelial‑Like Differentiation Of Immature Dendritic Cells
- Jak/Stat3 signaling pathway modulates human megakaryocytic differentiation
- Jak/Stat3 signaling promotes somatic cell reprogramming by epigenetic regulation
- Jak/Stat3 signalling is sufficient and dominant over antagonistic cues for the establishment of naive pluripotency
- Jak/Stat3: A Metabolic Hub Critical For Breast Cancer Stem Cell Maintenance
- Jak/Stat3-dependent activation of the RalGDS/Ral pathway in M1 mouse myeloid leukemia cells
- Jak/Stat3-Regulated Fatty Acid Β-Oxidation Is Critical For Breast Cancer Stem Cell Self-Renewal And Chemoresistance
- Jak/Stat5 Signaling Pathway Inhibitor Ruxolitinib Reduces Airway Inflammation Of Neutrophilic Asthma In Mice Model
- Jak/Stat5-Mediated Subtype-Specific Lymphocyte Antigen 6 Complex, Locus G6D (Ly6G6D) Expression Drives Mismatch Repair Proficient Colorectal Cancer
- Jak/Stat-Activating Genomic Alterations Are A Hallmark Of T-Pll
- Jak/Stat-dependent gene regulation by cytokines.
- Jak/Stat–Emerging Players In Metabolism
- Jak/Stat-regulated Heterochromatin Formation in Drosophila Stem Cell Maintenance
- Jak/StatS in Zebrafish
- Jak/Stat-signaling in function and developmentof normal and malignant hematopoiesis with focus on leukemic stem cells
- Jak/Stat-signaling in giant cell arteritis
- JAK: no longer’just another kinase’
- Jak: Using Dynamic Analysis To Crawl And Test Modern Web Applications
- JAK-1 rs2780895 C-related genotype and allele but not JAK-1 rs10789166, rs4916008, rs2780885, rs17127114, and rs3806277 are associated with higher …
- Jak2 46/1 Haplotype Is Associated With JAK 2 V617F–Positive Myeloproliferative Neoplasms In Brazilian Patients
- JAK‐2 as a novel mediator of the profibrotic effects of transforming growth factor β in systemic sclerosis
- Jak2 Disease-Risk Variants Are Gain Of Function And JAK Signaling Threshold Determines Innate Receptor-Induced Proinflammatory Cytokine Secretion In Macrophages
- JAK-2 Downregulation Sensitizes Pancreatic Cancer Cells to TRAIL Induced Cell Death by Augmenting Death Induced Signaling Complex Formation
- JAK-2 downregulation sensitizes pancreatic cancer cells to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced cell death
- Jak2 Inhibitor Blocks The Inflammation And Growth Of Esophageal Squamous Cell Carcinoma In Vitro Through The Jak/Stat3 Pathway
- JAK-2 Inhibitors And Allogeneic Transplant In Myelofibrosis
- JAK-2 Mutation Frequency In Patients With Thrombocytosis
- JAK-2 mutations and their relevance to myeloproliferative disease
- JAK-2 positive myeloproliferative neoplasms
- JAK2 the future: therapeutic strategies for JAK-dependent malignancies
- Jak2 tyrosine kinase residues glutamic acid 1024 and arginine 1113 form a hydrogen bond interaction that is essential for JAK-STAT signal transduction
- JAK-2 V617F Mutation Increases Heparanase Procoagulant Activity
- JAK-2_V617F_Mutational_Analysis_in_Primary_Idiopathic_Myelofibrosis_Experience_from_Southern_Pakistan/links/56b57f4608aebbde1a77c744.pdf”>JAK-2 V617F Mutational Analysis In Primary Idiopathic Myelofibrosis: Experience From Southern Pakistan
- JAK-2V617F Mutation in Acute Leukemia (South Egypt Experience)
- JAK2V617F-negative ET patients do not display constitutively active Jak/Stat signaling
- Jak3 Mutations In Italian Patients Affected By Scid: New Molecular Aspects Of A Long‐Known Gene
- JAK–cytokine receptor recognition, unboxed
- Jak’D Modular Drum System
- JAK-Ing Up Antibody Delivery To Cancer
- JAK-Ing Up Inadequate Ra Therapy
- JAK-Ing Up The Plaque’S Lipid Core…And Even More
- JAK-Ing Up The Response To Kit Inhibition
- ‘Jak–Ing’Up The Treatment Of Primary Myelofibrosis: Building Better Combination Strategies
- JAK-Inhibitors In Dermatology: Current Evidence And Future Applications
- JAK-Inhibitors Offer Promise For A New Era Of Targeted Treatment For Granulomatous Disorders
- JAK-Inhibitors. New Players In The Field Of Immune-Mediated Diseases, Beyond Rheumatoid Arthritis
- JAK-Mediated Autophagy Regulates Stemness And Cell Survival In Cisplatin Resistant Bladder Cancer Cells
- JAK-Mediated Phosphorylation and Activation of STAT Signaling Proteins
- JAK-mediated signaling inhibits Fas ligand-induced apoptosis independent of de novo protein synthesis
- JAK-mutant myeloproliferative neoplasms
- Jak—Opening The Door To Acquired Resistance
- JAK-STAT and AKT pathway-coupled genes in erythroid progenitor cells through ontogeny
- JAK-STAT and bone metabolism
- JAK-STAT and feeding
- JAK-Stat And G-Protein-Coupled Receptor Signaling Pathways Are Frequently Altered In Epitheliotropic Intestinal T-Cell Lymphoma
- JAK-STAT and intestinal mucosal immunology
- JAK–STAT and JAK–PI3K–mTORC1 pathways regulate telomerase transcriptionally and posttranslationally in ATL cells
- JAK-STAT and the renin-angiotensin system: the role of the JAK-STAT pathway in blood pressure and intrarenal renin-angiotensin system regulation
- JAK-STAT blockade inhibits tumor initiation and clonogenic recovery of prostate cancer stem-like cells
- JAK-STAT Cell Signaling Pathways Adjusting by Gualou Xiebai Banxia Decoction Preconditioning in Myocardial Ischemia Reperfusion Injury [J]
- JAK-STAT in heterochromatin and genome stability
- JAK-STAT in lipid metabolism of adipocytes
- JAK-Stat In Lymphoproliferative Disorders
- JAK-Stat Inhibitors For The Treatment Of Immunomediated Diseases
- JAK–STAT is restrained by Notch to control cell proliferation of the Drosophila intestinal stem cells
- JAK-STAT Pathway
- JAK‐STAT Pathway
- Jak–Stat Pathway Activation In Copd
- Jak–Stat Pathway Activation In Malignant And Nonmalignant Cells Contributes To Mpn Pathogenesis And Therapeutic Response
- Jak‐Stat Pathway Activation In Response To Spinal Cord Injury In Regenerative And Non‐Regenerative Stages Of Xenopus Laevis
- Jak‐Stat Pathway And Epigenetic Regulators Are Critical Players In Bi‐Alcl Pathogenesis?
- JAK-STAT_pathway_and_JAK_inhibitors_a_primer_for_dermatologists/links/5d7d9b66a6fdcc2f0f6fbba2/JAK-STAT-pathway-and-JAK-inhibitors-a-primer-for-dermatologists.pdf”>JAK-Stat Pathway And JAK Inhibitors: A Primer For Dermatologists
- JAK-STAT pathway and myogenic differentiation
- JAK-STAT pathway in carcinogenesis: is it relevant to cholangiocarcinoma progression
- JAK-STAT pathway in cardiac ischemic stress
- JAK-STAT pathway in disease
- JAK-STAT pathway in Drosophila morphogenesis: From organ selector to cell behavior regulator
- JAK-Stat pathway in response to virus infection
- JAK-STAT pathway in the control of mycobacterial infections
- JAK-Stat Pathway Induces Drosophila Follicle Elongation By A Gradient Of Apical Contractility
- JAK-stat pathway mediated activation of renin angiotensin system in myocardial hypertrophy and ischemia
- JAK-Stat Pathway Mediates Anti-Oxidative Effects Of Gx-50 On Neuron
- JAK-STAT pathway modulates NF-кB-mediated cytoprotection of H_2O_2 preconditioning
- JAK-STAT pathway modulates the roles of iNOS and COX-2 in the cytoprotection of early phase of hydrogen peroxide preconditioning against apoptosis induced by …
- JAK-Stat Pathway: Testicular Development, Spermatogenesis And Fertility
- JAK-STAT%20Pathway%20Role%20in_immunology_Issue2_June2018.pdf”>JAK-Stat Pathway-Role In Immunology
- JAK-STAT regulation of cyst stem cell development in the Drosophila testis
- Jak–STAT regulation of male germline stem cell establishment during Drosophila embryogenesis
- JAK-STAT signal inhibition regulates competition in the Drosophila testis stem cell niche
- JAK-Stat signal transduction pathway through the eyes of cytokine class II receptor complexes
- JAK-STAT Signaling
- JAK-STAT signaling activated by Abl oncogenes
- JAK-STAT signaling and myocardial glucose metabolism
- Jak–Stat Signaling As A Target For Inflammatory And Autoimmune Diseases: Current And Future Prospects
- JAK-STAT signaling circuits in myocarditis and dilated cardiomyopathy
- JAK-STAT signaling in asthma
- JAK-Stat Signaling In Cancer: From Cytokines To Non-Coding Genome
- JAK-STAT signaling in cardiomyogenesis of cardiac stem cells
- JAK-Stat Signaling In Diseases
- JAK-STAT signaling in hepatic fibrosis
- JAK-STAT signaling in liver disease and repair: a way of living
- JAK-STAT signaling in stem cells
- JAK-STAT signaling in stem cells and their niches in Drosophila
- JAK-Stat Signaling In The Therapeutic Landscape Of Myeloproliferative Neoplasms
- JAK-Stat Signaling Induced By Interleukin-6 Family Cytokines In Hepatocellular Carcinoma
- JAK–STAT signaling involved in phorbol 12-myristate 13-acetate-and dimethyl sulfoxide-induced 2′-5′ oligoadenylate synthetase expression in human HL-60 …
- JAK-Stat Signaling Is Activated In The Kidney And Peripheral Blood Cells Of Patients With Focal Segmental Glomerulosclerosis
- JAK-Stat Signaling Jump Starts The Hair Cycle
- JAK-STAT signaling mediates gangliosides-induced inflammatory responses in brain microglial cells
- JAK-Stat Signaling Mediates The Senescence Of Bone Marrow-Mesenchymal Stem Cells From Systemic Lupus Erythematosus Patients
- JAK-Stat Signaling Pathway And Leukemia. Docx
- JAK—STAT signaling pathway in pulmonary arterial smooth muscle cells is activated by hypoxia
- Jak‐Stat Signaling Pathway Inhibition: A Role For Treatment Of Discoid Lupus Erythematosus And Dermatomyositis
- JAK-Stat Signaling Pathway Inhibition: A Role For Treatment Of Various Dermatologic Diseases.
- JAK-Stat signaling pathway may play a role in the pathogenesis of cholesteatoma
- JAK‐STAT signaling pathway mediates astrogliosis in brains of scrapie‐infected mice
- JAK-stat-signaling-pathways”>JAK-Stat Signaling Pathways
- JAK-Stat Signaling Pathways And Inhibitors Affect Reversion Of Envelope-Mutated Hiv-1
- JAK-STAT signaling pathways are activated in the brain following reovirus infection
- JAK-STAT signaling pathways in cells of the immune system.
- JAK-Stat Signaling Regulation Of Chicken Embryonic Stem Cell Differentiation Into Male Germ Cells
- JAK-Stat Signaling: A Double-Edged Sword Of Immune Regulation And Cancer Progression
- JAK-stat signaling: from basics to disease
- JAK-STAT signaling: from interferons to cytokines
- JAK-Stat Signalling And The Atrial Fibrillation Promoting Fibrotic Substrate
- JAK-Stat Signalling And The Atrial Fibrillation-Promoting Fibrotic Substrate: Pathogenic Role And Possible Therapeutic Target
- JAK-STAT signalling as example for a database-supported modular modelling concept
- JAK-STAT signalling at chromatin
- Jak–Stat Signalling Controls Cancer Stem Cell Properties Including Chemotherapy Resistance In Myxoid Liposarcoma
- JAK-STAT signalling is required throughout telotrophic oogenesis and short-germ embryogenesis of the beetle Tribolium
- JAK-STAT SIGNALLING PATHWAY PROTEINS ARE OVER EXPRESSED IN ARTERIAL HUMAN ENDOTHELIAL CELLS EXPOSED TO OXIDIZED LOW DENSITY …
- JAK-STAT signalling: methods and protocols
- JAK-STAT Volume 2, Issue 2 Table of Contents
- JAK-STAT: Getting to the heart of the matter
- JAK-STAT1/3-induced expression of signal sequence-encoding proopiomelanocortin mRNA in lymphocytes reduces inflammatory pain in rats
- JAK-STAT3 and somatic cell reprogramming
- JAK-STAT3 pathway regulates spinal astrocyte proliferation and neuropathic pain maintenance in rats
- JAK-Stat3 Pathway Triggers Dicer1 For Proteasomal Degradation By Ubiquitin Ligase Complex Of Cul4Adcaf1 To Promote Colon Cancer Development
- JAK-Stat6 Pathway Inhibitors Block Eotaxin-3 Secretion By Epithelial Cells And Fibroblasts From Esophageal Eosinophilia Patients: Promising Agents To Improve …
- JAK-Stat-Mediated Chronic Inflammation Impairs Cytotoxic T Lymphocyte Activation To Decrease Anti-Pd-1 Immunotherapy Efficacy In Pancreatic Cancer
- JAK-Tgfβ Cross-Talk Links Transient Adipose Tissue Inflammation To Beige Adipogenesis
- JANEX-1, a JAK3 inhibitor, protects pancreatic islets from cytokine toxicity through downregulation of NF-κB activation and the Jak/Stat pathway
- Janus Kinase (JAK)
- Janus kinase (JAK) 2 V617F mutation as the cause of primary thrombocythemia in acromegaly with severe visceromegaly and divergence between growth hormone …
- Janus kinase (JAK) 2 V617F mutation in Asian Indians with cerebral venous thrombosis and without overt myeloproliferative disorders
- Janus Kinase (JAK) 3 Inhibitor, R256, Attenuates Allergen-Induced Airway Hyperresponsiveness And Airway Inflammation In Mice
- Janus Kinase (Jak) Inhibitors For The Treatment Of Skin And Hair Disorders: A Review Of Literature
- Janus Kinase (Jak) Inhibitors In The Treatment Of Inflammatory And Neoplastic Diseases
- Janus Kinase (JAK)-Signal Transducer and Activator of Transcription (STAT) Pathway in Heart Disease
- Janus Kinase Enzyme (Jak) Inhibitors And Rheumatoid Arthritis: A Review Of The Literature
- JANUS under stress—role of Jak/Stat signaling pathway in vascular diseases
- Jnk And Jak/Stat Signalling Are Required For Inducing Loss Of Cell Fate Specification During Imaginal Wing Discs Regeneration In Drosophila Melanogaster
- Joint Location–Specific Jak‐Stat Signaling In Rheumatoid Arthritis Fibroblast‐Like Synoviocytes
- Kaempferol 7-O-Β-D-Glucoside Isolated From The Leaves Of Cudrania Tricuspidata Inhibits Lps-Induced Expression Of Pro-Inflammatory Mediators Through Inactivation Of Nf-Κb, Ap-1, And JAK-Stat In Raw 264.7 Macrophages
- Kaempferol inhibits chemokine expression and attenuates airway inflammation by suppressing STAT/JAK and NF-kB activity in human airway epithelial cells
- Ken & barbie selectively regulates the expression of a subset of Jak/Stat pathway target genes
- Kif20A Promotes Cellular Malignant Behavior And Enhances Resistance To Chemotherapy In Colorectal Cancer Through Regulation Of The Jak/Stat3 Signaling Pathway.
- Kilham rat virus-induced type 1 diabetes involves beta cell infection and intra-islet JAK–STAT activation prior to insulitis
- Kinase regulation: competing phosphatases in JAK dephosphorylation
- Kinase-Independent Small-Molecule Inhibition Of JAK-Stat Signaling
- Kit D816V And Jak2 V617F Mutations Are Seen Recurrently In Hypereosinophilia Of Unknown Significance
- Klf 4 Knockdown Attenuates Tbi‐Induced Neuronal Damage Through P53 And Jak‐Stat 3 Signaling
- Knockdown Of Long Non-Coding Rna Linc00518 Inhibits Cervical Cancer Proliferation And Metastasis By Modulating Jak/Stat3 Signaling
- Knockdown Of Rpl34 Inhibits The Proliferation And Migration Of Glioma Cells Through The Inactivation Of Jak/Stat3 Signaling Pathway
- Kurarinone regulates immune responses through regulation of the Jak/Stat and TCR-mediated signaling pathways
- Kyungheechunggan-Tang-01, A New Herbal Medication, Suppresses Lps-Induced Inflammatory Responses Through Jak/Stat Signaling Pathway In Raw 264.7 …
- La voie de signalisation Jak/Stat dans la leucémogenèse
- Lack Of Association Between Genetic Polymorphisms Of JAK-Stat Signaling Pathway Genes And Acute Anterior Uveitis In Han Chinese
- Lactobacillus rhamnosus GR-1-induced IL-10 production in human placental trophoblast cells involves activation of Jak/Stat and MAPK pathways
- Lactogenic Hormones Regulate Mammary Protein Synthesis In Bovine Mammary Epithelial Cells Via The Mtor And Jak–Stat Signal Pathways
- Lanatoside C Induces G2/M Cell Cycle Arrest And Suppresses Cancer Cell Growth By Attenuating Mapk, Wnt, JAK-Stat, And Pi3K/Akt/Mtor Signaling Pathways
- Large Granular Lymphocytic Leukemia And Jak/Stat Signaling Pathway–Review
- Lb0001 Baricitinib, An Oral Janus Kinase (Jak) 1/Jak2 Inhibitor, In Patients With Active Rheumatoid Arthritis (Ra) And An Inadequate Response To Cdmard Therapy …
- Legenda o Wandzie, czyli JAK wychować Wandala?
- Leptin enhances α1(I) collagen gene expression in LX‐2 human hepatic stellate cells through JAK‐mediated H2O2‐dependent MAPK pathways
- Leptin impairs myogenesis in C2C12 cells through Jak/Stat and MEK signaling pathways
- Leptin induces cyclin D1 expression and proliferation of human nucleus pulposus cells via Jak/Stat, PI3K/Akt and MEK/ERK pathways
- JAK-2_independent_IRS-1PI-3_kinase_dependent_pathway_Running_Title_Leptin_and_apoptosis_in_thymus/links/5464876d0cf2cb7e9daa1064.pdf”>Leptin inhibits apoptosis in thymus through a JAK-2 independent, IRS-1/PI-3 kinase dependent pathway
- Leptin play the key role in astroglial differentiation of mouse neural stem cells and regulated the STAT3 signaling through JAK-STAT3 pathway
- Leptin regulates chondrogenic differentiation in ATDC5 cell-line through Jak/Stat and MAPK pathways
- Leptin-induced cardioprotection involves Jak/Stat signaling that may be linked to the mitochondrial permeability transition pore
- Leptin-Induced Er-Α-Positive Breast Cancer Cell Viability And Migration Is Mediated By Suppressing Ccn5-Signaling Via Activating Jak/Akt/Stat-Pathway
- Leptin-Induced Jak/Stat Signaling And Cancer Growth
- Leptin-mediated cell survival signaling in hippocampal neurons mediated by JAK STAT3 and mitochondrial stabilization
- Lestaurtinib inhibition of the Jak/Stat signaling pathway in hodgkin lymphoma inhibits proliferation and induces apoptosis
- Leukemia inhibitory factor (LIF) regulates Jak/Stat and canonical Wnt/β-catenin signaling pathways during murine embryo implantation.
- Leukemia Inhibitory Factor Activates JAK-STAT Pathway in Side Population Cells and Enhances Stem Cell-Derived Cardiomyocyte Renewal after Myocardial …
- Leukemia inhibitory factor regulates differentiation of trophoblastlike BeWo cells through the activation of Jak/Stat and MAPK3/1 MAP kinase-signaling pathways
- Leveraging JAK-Stat Regulation In Myelofibrosis To Improve Outcomes With Allogeneic Hematopoietic Stem-Cell Transplant
- Lif-Activated JAK Signaling Determines Esrrb Expression During Late-Stage Reprogramming
- LIF-independent JAK signalling to chromatin in embryonic stem cells uncovered from an adult stem cell disease
- Ligustrazine Attenuates Neuropathic Pain By Inhibition Of Jak/Stat3 Pathway In A Rat Model Of Chronic Constriction Injury
- Linc00346 Promotes Hepatocellular Carcinoma Progression Via Activating The Jak‐Stat3 Signaling Pathway
- Linc01116 Targets Mir-520A-3P And Affects Il6R To Promote The Proliferation And Migration Of Osteosarcoma Cells Through The JAK-Stat Signaling Pathway
- Linderalactone Inhibits Human Lung Cancer Growth By Modulating The Expression Of Apoptosis-Related Proteins, G2/M Cell Cycle Arrest And Inhibition Of Jak/Stat Signalling Pathway
- Linkage between α1 adrenergic receptor and the Jak/Stat signaling pathway in vascular smooth muscle cells
- linkh betlween cases of von Jak~ schi’s aniaemia, of achioluiric jaundice, aind of the splenic anaemia of adults. Cases of acholuric and haemolytic jaundice were …
- Linking Energy Sensing To Suppression Of JAK-Stat Signalling: A Potential Route For Repurposing Ampk Activators?
- Lipopolysaccharide Promoted Proliferation And Adipogenesis Of Preadipocytes Through Jak/Stat And Ampk-Regulated Cpla2 Expression
- Lncrna Ab073614 Induces Epithelial-Mesenchymal Transition Of Colorectal Cancer Cells Via Regulating The Jak/Stat3 Pathway
- Lncrna H19 Contributes To Hippocampal Glial Cell Activation Via Jak/Stat Signaling In A Rat Model Of Temporal Lobe Epilepsy
- Lncrna H19 Suppresses Metastasis Of Follicular Thyroid Carcinoma Via The Igf1/Jak/Stat Pathway
- Lncrna Meg3 Suppresses Migration And Promotes Apoptosis By Sponging Mir‐548D‐3P To Modulate Jak–Stat Pathway In Oral Squamous Cell Carcinoma
- Lncrna Znf667-As1 Inhibits Inflammatory Response And Promotes Recovery Of Spinal Cord Injury Via Suppressing JAK-Stat Pathway
- Lncrna-135528 Inhibits Tumor Progression By Up-Regulating Cxcl10 Through The Jak/Stat Pathway
- Lncrna-Uca1 Inhibits The Astrocyte Activation In The Temporal Lobe Epilepsy Via Regulating Jak/Stat Signaling Pathway
- Localised Jak/Stat pathway activation is required for Drosophila wing hinge development
- Localized Jak/Stat signaling is required for oriented cell rearrangement in a tubular epithelium
- Loganin Alleviates Lps‐Activated Intestinal Epithelial Inflammation By Regulating Tlr4/Nf‐Κb And Jak/Stat3 Signaling Pathways
- Long lasting macrophage cytokine suppression by alpha 7 nAChR requires Jak/Stat (138.23)
- Long Noncoding Rna Fezf1-As1 Promotes Proliferation And Inhibits Apoptosis In Ovarian Cancer By Activation Of JAK-Stat3 Pathway
- Long Non-Coding Rna Itih4-As1 Accelerates The Proliferation And Metastasis Of Colorectal Cancer By Activating Jak/Stat3 Signaling
- Long Non-Coding Rna P4713 Contributes To The Malignant Phenotypes Of Oral Squamous Cell Carcinoma By Activating The Jak/Stat3 Pathway
- Long Noncoding Rna Part1 Promotes Progression Of Non‐Small Cell Lung Cancer Cells Via Jak‐Stat Signaling Pathway
- Long Non-Coding Rna Rp11-468E2. 5 Curtails Colorectal Cancer Cell Proliferation And Stimulates Apoptosis Via The Jak/Stat Signaling Pathway By Targeting …
- Longer Warm Ischemia Can Accelerate Tumor Growth Through The Induction Of Hif‐1Α And The Il‐6–Jak–Stat3 Signaling Pathway In A Rat Hepatocellular Carcinoma …
- Long‐range effect of upd, a ligand for Jak/Stat pathway, on cell cycle in Drosophila eye development
- Long‐Term Follow‐Up Of Essential Thrombocythemia Patients Treated With Anagrelide: Subgroup Analysis According To Jak2/Calr/Mpl Mutational Status
- Long-term regulation of Na+, K+-ATPase pump in human lymphocytes: the role of Jak/Stat-and MAPK-signaling pathways
- Long-term regulation of Na+/K+-ATPase pump in human lymphocytes: Role of Jak/Stat and MAPK signaling pathways
- Long-Term Use Of Indomethacin Leads To Poor Prognoses Through Promoting The Expression Of Pd-1 And Pd-L2 Via Trif/Nf-Κb Pathway And Jak/Stat3 Pathway To …
- Loss Of Mlh1 Expression Promotes The Acquisition Of Oncogenic Jak1 And Jak3 Mutations That Cooperatively Increase Resistance To JAK Inhibitors
- Loss Of The Mucosal Barrier Alters The Progenitor Cell Niche Via Janus Kinase/Signal Transducer And Activator Of Transcription (Jak/Stat) Signaling
- Low amino acids affect expression of 11β-HSD2 in BeWo cells through leptin-activated JAK-STAT and MAPK pathways
- Lps Exposure In Early Life Protects Against Mucus Hypersecretion In Ovalbumin-Induced Asthma By Down-Regulation Of The Il-13 And JAK-Stat6 Pathways
- L-Theanine Down-Regulates The Jak/Stat3 Pathway To Attenuate The Proliferation And Migration Of Vascular Smooth Muscle Cells Induced By Angiotensin Ii
- Łukasz Garbal, Edytorstwo. JAK Wydawać Współczesne Teksty Literackie
- Lung Clear “Sugar” Cell Tumor and JAK V617F Positive Essential Thrombocythemia: a Simple Coincidence?
- Luteolin arrests cell cycling, induces apoptosis and inhibits the Jak/Stat3 pathway in human cholangiocarcinoma cells
- Luteolin Suppresses The Jak/Stat Pathway In A Cellular Model Of Intestinal Inflammation
- LY2784544, a small molecule JAK2 inhibitor, induces apoptosis in inflammatory breast cancer spheres through targeting IL-6-JAK-STAT3 pathway
- Lyssavirus Matrix Protein Cooperates With Phosphoprotein To Modulate The JAK-Stat Pathway
- Macrophage hypo-responsiveness to interferon-γ in aged mice is associated with impaired signaling through JAK-STAT
- Macrophages And Cd4 T-Cells In Rheumatoid Arthritis And Their Modulation By JAK Inhibitors
- Macte nova virtute, puer!”: Gilbert Murray as mentor and friend to JAK Thomson’
- Mala Wielka Zmiana. JAK Skutecznie Wywierac Wplyw [The Small Big. Small Changes That Spark Big Influence]
- Malignant Astrocytic Tumor Progression Potentiated By JAK-Mediated Recruitment Of Myeloid Cells
- Managing Side Effects Of JAK Inhibitors For Myelofibrosis In Clinical Practice
- Mapk And Jak/Stat Pathways Targeted By Mir-23A And Mir-23B In Prostate Cancer: Computational And In Vitro Approaches
- MAPK and JAK-STAT signaling pathways are involved in the oxidative stress–induced decrease in expression of surfactant protein genes
- Mapping The Transcriptome Of Neuronal Jak/Stat Signaling In Response To Status Epilepticus
- Mast cell homeostasis and the JAK–STAT pathway
- Maternal Exposure To No2 Enhances Airway Sensitivity To Allergens In Balb/C Mice Through The JAK-Stat6 Pathway
- Mathematical Modelling of Interleukin-6 induced Jak/Stat Pathway.
- Matrix Metalloproteinase 9 Facilitates Hepatitis B Virus Replication Through Binding With Type I Interferon (Ifn) Receptor 1 To Repress Ifn/Jak/Stat Signaling
- Matrix metalloproteinase-13 expression in IL-1β-treated chondrocytes by activation of the p38 MAPK/c-Fos/AP-1 and Jak/Stat pathways
- Maybe We Don’T Know Jak?
- Mda‐7/IL‐24 induces apoptosis of diverse cancer cell lines through Jak/Stat‐independent pathways
- Mechanical Stress To Drosophila Larvae Stimulates A Cellular Immune Response Through The Jak/Stat Signaling Pathway
- Mechanism Of JAK-Stat Signaling Pathway Inhibitor In Post-Spinal Cord Injury
- Mechanism-Based Treatment Strategies For Ibd: Cytokines, Cell Adhesion Molecules, JAK Inhibitors, Gut Flora, And More
- Mechanisms And Consequences Of Jak–Stat Signaling In The Immune System
- Mechanisms of chronic JAK-STAT3-SOCS3 signaling in obesity
- Mechanisms Of Jak/Stat Pathway Negative Regulation By The Short Coreceptor Eye Transformer/Latran
- Mechanisms Of Jak/Stat Signaling In
- Mechanisms Of Jak/Stat Signaling In Immunity And Disease
- Mechanistically probing lipid-siRNA nanoparticle-associated toxicities identifies JAK inhibitors effective in mitigating multifaceted toxic responses
- Mechanosignaling Through Caveolae: A New Role For The Control Of JAK-Stat Signaling
- Mediator Kinase Phosphorylation Of Stat1 S727 Promotes Growth Of Neoplasms With JAK-Stat Activation
- Mediators of the Jak/Stat signaling pathway in human spermatozoa
- Mek2 Promotes The Replication Of Porcine Pestivirus Via The JAK-Stat Signaling Pathway
- Melanoma cell lines express the receptor for interleukin-29 and respond via the Jak/Stat signaling pathway
- Melanoma: Jak—Opening The Door To Acquired Resistance
- Melatonin Attenuates Early Brain Injury After Subarachnoid Hemorrhage By The JAK-Stat Signaling Pathway
- Members of the Janus kinase/signal transducers and activators of transcription (Jak/Stat) pathway are present and active in human sperm
- Mercury abolishes neurotrophic factor–stimulated JAK-STAT signaling in nerve cells by oxidative stress
- Mest Induces Epithelial-Mesenchymal Transition Through Il-6/Jak/Stat3 Signaling In Breast Cancers
- Metabolites and Jak/Stat pathway were involved in the liver and spleen damage in male Wistar rats fed with mequindox
- Metallothionein induces a regenerative reactive astrocyte phenotype via Jak/Stat and RhoA signalling pathways
- Meteorin promotes the formation of GFAP-positive glia via activation of the JAK-STAT3 pathway
- Metformin Inhibits Esophageal Squamous Cell Carcinoma-Induced Angiogenesis By Suppressing Jak/Stat3 Signaling Pathway
- Methamphetamine And The Jak/Stat Pathway
- Methylation silencing of SOCS-3 promotes cell growth and migration by enhancing Jak/Stat and FAK signalings in human hepatocellular carcinoma
- Methylome analysis reveals JAK-STAT pathway deregulation in putative breast cancer stem cells
- Methylprednisolone induces apoptosis by interacting with the Jak/Stat pathway in HL-60 and K-562 leukemic cells
- Mgcracgap Inhibition Stimulates JAK-Dependent Stat3 Activity
- Micorna-301A Promotes Pancreatic Cancer Invasion And Metastasis Through The Jak/Stat3 Signaling Pathway By Targeting Socs5
- Microenvironmental Triggers Induce A Chemoresistant, Differentiated Subset Of S100A8/A9High Aml Cells Via The Jak/Stat3 Signaling Axis
- Microenvironment-mediated reversion of epiblast stem cells by reactivation of repressed JAK–STAT signaling
- Microfluidic generated EGF-gradients induce chemokinesis of transplantable retinal progenitor cells via the Jak/Stat and PI3kinase signaling pathways
- Microrna Regulation Of JAK-Stat System In The Atrial Fibrillation-Related Fibrotic Response
- Microrna-125B Promotes The Regeneration And Repair Of Spinal Cord Injury Through Regulation Of Jak/Stat Pathway
- Microrna-146A Reduces Mhc-Ii Expression Via Targeting Jak/Stat Signaling In Dendritic Cells After Stem Cell Transplantation
- Microrna-196A/-196B Regulate The Progression Of Hepatocellular Carcinoma Through Modulating The Jak/Stat Pathway Via Targeting Socs2
- Microrna-218 Alleviates Sepsis Inflammation By Negatively Regulating Vopp1 Via Jak/Stat Pathway
- microRNA-279 acts through the Jak/Stat pathway to regulate circadian behavioral output in Drosophila
- Microrna-294 Promotes Cellular Proliferation And Motility Through The Pi3K/Akt And Jak/Stat Pathways By Upregulation Of Nras In Bladder Cancer
- Microrna‐30A Inhibits The Liver Cell Proliferation And Promotes Cell Apoptosis Through The Jak/Stat Signaling Pathway By Targeting Socs‐1 In Rats With Sepsis
- Microrna-30E-5P Suppresses Non-Small Cell Lung Cancer Tumorigenesis By Regulating Usp22-Mediated Sirt1/Jak/Stat3 Signaling
- Microrna-Messenger Rna Interactions Involving JAK-Stat Signaling Genes In Colorectal Cancer
- Micrornas Are Part Of The Regulatory Network That Controls Egf Induced Apoptosis, Including Elements Of The Jak/Stat Pathway, In A431 Cells
- Mining for JAK–STAT mutations in cancer
- Mir-107 Target Nid2 Regulating Invasion And Proliferation Of Lung Cancer By Jak/Stat Signaling Pathway
- Mir-146A Down-Regulation Alleviates H2O2-Induced Cytotoxicity Of Pc12 Cells By Regulating Mcl1/Jak/Stat Pathway
- miR-155 meets the Jak/Stat pathway
- Mir-155 Regulates Lymphoma Cell Proliferation And Apoptosis Through Targeting Socs3/JAK-Stat3 Signaling Pathway
- Mir‐181A And Mir‐150 Regulate Dendritic Cell Immune Inflammatory Responses And Cardiomyocyte Apoptosis Via Targeting Jak1–Stat1/C‐Fos Pathway
- Mir-198 Affects The Proliferation And Apoptosis Of Colorectal Cancer Through Regulation Of Adam28/JAK-Stat Signaling Pathway
- miR-19a: an effective regulator of SOCS3 and enhancer of JAK-STAT signalling
- Mir-19B-3P Integrates JAK-Stat Signaling Pathway Through Plzf To Regulate Self-Renewal In Dairy Goat Male Germline Stem Cells
- Mir-203 Regulates JAK-Stat Pathway In Affecting Pancreatic Cancer Cells Proliferation And Apoptosis By Targeting Socs3
- Mir-210 Inhibits Apoptosis Of Vascular Endothelial Cells Via JAK-Stat In Arteriosclerosis Obliterans.
- Mir-221 Affects Cholangiocarcinoma Cell Proliferation And Apoptosis By Targeting The Socs3/JAK-Stat Signaling Pathway
- Mir-30 Overexpression Promotes Glioma Stem Cells By Regulating Jak/Stat3 Signaling Pathway
- Mir-340 Affects Gastric Cancer Cell Proliferation, Cycle, And Apoptosis Through Regulating Socs3/JAK-Stat Signaling Pathway
- Mir-410 Affects The Proliferation And Apoptosis Of Lung Cancer A549 Cells Through Regulation Of Socs3/JAK-Stat Signaling Pathway
- Mir-410 Affects The Proliferation And Apoptosis Of Lung Cancer A549 Cells Through Regulation Of Socs3/JAK-Stat Signaling Pathway.
- miRNA-mediated feedback inhibition of Jak/Stat morphogen signalling establishes a cell fate threshold
- Mitochondrial Dysfunction Regulates The Jak/Stat Pathway By Lkb1-Mediated Ampk Activation In An Er Stress-Independent Manner
- Miyabenol A exhibits anti-inflammatory activity through down-regulation of LPS-induced NF-κB and Jak/Stat pathways in RAW 264.7 macrophages
- MLS-2384, a new 6-bromoindirubin derivative with dual JAK/Src kinase inhibitory activity, suppresses growth of diverse cancer cells
- Mmp-9 Facilitates Hepatitis B Virus Replication Through Binding With Ifnar1 To Repress Ifn/Jak/Stat Signaling
- Model-based selection of the robust JAK-STAT activation mechanism
- Model-driven experimental analysis of the function of SHP-2 in IL-6-induced Jak/Stat signaling
- Modelling Of Tlr4 And Jak/Stat Signalling Pathways And Protein-Protein Interaction Studies To Examine The Pathophysiology Of Sepsis
- Moderate Exercise Reduces Food Consumption in Obese Mice for Activate JAK-2/Stat-3 Pathway in the Hypothalami
- Modulation of activation-loop phosphorylation by JAK inhibitors is binding mode dependent
- Modulation of activation-loop phosphorylation by JAK inhibitors is mode of action dependent
- Modulation of antiangiogenic resistance: Targeting the Jak/Stat3 pathway in glioblastoma.
- Modulation of CD4+ Foxp3− T-cells with a JAK-STAT5 kinase inhibitor (131.2)
- Modulation of HLA-DR On Conjunctival Cells And Inflammatory Mediators In Tears In Dry Eye Patients By CP-690,550, A Selective Inhibitor of The JAK Family
- Modulation of human JAK-STAT pathway signaling by functionally conserved regulators
- Modulation Of Osteogenic And Myogenic Differentiation By A Phytoestrogen Formononetin Via P38Mapk-Dependent JAK-Stat And Smad-1/5/8 Signaling …
- Modulation of the JAK/ERK/STAT signaling in melanocortin-induced inhibition of local and systemic responses to myocardial ischemia/reperfusion
- MOG₃₅₋ ₅₅ iv suppresses experimental autoimmune encephalomyelitis partially through modulation of Th17 and Jak/Stat pathways
- MOG35-55 iv Suppress Experimental Autoimmune Encephalomyelitis through Modulation of Pro-Inflammatory Cytokines and Jak/Stats Pathway
- MOG35–55 iv suppresses experimental autoimmune encephalomyelitis partially through modulation of Th17 and Jak/Stat pathways
- Molecular components of Jak/Stat signaling pathway and its connection with transcription machinery
- Molecular components of Jak/Stat signaling pathway and its interaction with transcription machinery
- Molecular diagnosis of the myeloproliferative neoplasms: UK guidelines for the detection of JAK2 V617F and other relevant mutations
- Molecular Docking, 3D Qsar And Dynamics Simulation Studies Of Imidazo-Pyrrolopyridines As Janus Kinase 1 (JAK 1) Inhibitors
- Molecular Dynamics Study Of Egfr And JAK Kinases In Active, Inactive And Mutant Forms
- Molecular mechanism of hepcidin-mediated ferroportin internalization requires ferroportin lysines, not tyrosines or JAK-STAT
- Molecular pathways: Jak/Stat pathway: mutations, inhibitors, and resistance
- Molecular pathways: molecular basis for sensitivity and resistance to JAK kinase inhibitors
- Molecular Testing For JAK 2, Mpl, And Calr In Myeloproliferative Neoplasms
- Mollugin inhibits the inflammatory response in LPS-stimulated RAW264. 7 macrophages by blocking the Janus kinase (JAK)-signal transducers and activators of …
- mom identifies a receptor for the Drosophila Jak/Stat signal transduction pathway and encodes a protein distantly related to the mammalian cytokine receptor family
- Monitoring of the immunomodulatory effect of CP-690,550 by analysis of the Jak/Stat pathway in kidney transplant patients
- Moonlighting Α-Phers Connects Jak/Stat With Notch Signaling For Intestinal Homeostasis
- Mouse models of myeloproliferative neoplasms: JAK of all grades
- Mp426 The Effect Of Glucagon-Like-Peptide-1 And Vitamin D On JAK-Stat Pathway In Dbdb Mice And In Endotelial Cells Exposed To A …
- MsSOCS expression indicates a potential role for Jak/Stat signalling in the early stages of Manduca sexta spermatogenesis
- Multimodal action of the Hsp90 inhibitor STA-9090 in treating cancer cells with activated Jak/Stat signaling
- Multimodaling And Multilanguaging: Charting Student (Open) Access And (Communal) Success Through Multiliteracies/JAK Olivier
- Multiple Pulmonary And Splenic Infarcts Triggered By Acute Cmv Infection And Transient Double Antiphospholipid Antibody Positivity In A Patient Carrier For JAK …
- Mutated JAK Kinases And Deregulated Stat Activity Are Potential Therapeutic Targets In Cutaneous T-Cell Lymphoma
- Mutation of the inhibitory adaptor protein LNK drives potentiated JAK-STAT signaling in patients with JAK2 V617F-negative myeloproliferative neoplasms
- Mutations in JAK2V617F homologous domain of JAK genes are uncommon in solid tumors
- Mutations In The Jak/Stat And Ras Signaling Pathways Are Common In Intestinal T-Cell Lymphomas
- Mutations In The Jak/Stat Pathway Genes And Activation Of The Pathway, A Relevant Finding In Nodal Peripheral T‐Cell Lymphoma
- Mycobacterium bovis bacillus Calmette-Gueérin infection promotes SOCS induction and inhibits IFN-γ-stimulated Jak/Stat signaling in J774 macrophages
- Myeloproliferative Neoplasm Or Reactive Process? A Rare Case Of Acute Myeloid Leukemia And Transient Posttreatment Megakaryocytic Hyperplasia With JAK-2 Mutation
- Myeloproliferative Neoplasm or Reactive Process? A Rare Case of Acute Myeloid Leukemia and Transient Post-Treatment Megakaryocytic Hyperplasia with JAK-2 …
- Myeloproliferative Neoplasms And The Jak/Stat Signaling Pathway: An Overview
- Myocardial ischemia activates the JAK–STAT pathway through angiotensin II signaling in in vivo myocardium of rats
- Myricetin Exerts Anti-Osteoarthritic Effects In Il-1Β Stimulated Sw1353 Cells Via Regulating Matrix Metalloproteinases And Modulating Jnk/P38Mapk/Ap-1/C-Fos And Jak/Stat Signalling
- Myxovirus Resistance Protein A Inhibits Hepatitis C Virus Replication Through JAK-Stat Pathway Activation
- N-acetyl cysteine regulates the phosphorylation of JAK proteins following CD40-activation of human memory B cells
- N-Acetylcysteine and allopurinol up-regulated the Jak/Stat3 and PI3K/Akt pathways via adiponectin and attenuated myocardial postischemic injury in diabetes
- Narrative-based computational modelling of the Gp130/Jak/Stat signalling pathway
- Narzędzie Modernizacji W Kłopotach: JAK Kryzys W Strefie Euro Zmienił Politykę Spójności
- Ndp-Α-Msh Attenuates Heart And Liver Responses To Myocardial Reperfusion Via The Vagus Nerve And Jak/Erk/Stat Signaling
- Negative regulation of Drosophila JAK–STAT signalling by endocytic trafficking
- Negative Regulation Of Interferon Lambda Induced JAK-Stat Signaling And Development Of Patient-Derived Xenograft Models From Fresh Human Hepatocellular …
- Negative regulation of Jak/Stat pathway
- Negative regulation of the Jak/Stat: pathway implication in tumorigenesis
- Negative Regulators Of Jak/Stat Signaling In Rheumatoid Arthritis And Osteoarthritis
- Negative regulators of the Jak/Stat pathway
- Network Pharmacology Of JAK Inhibitors
- Neuregulin-1 activates the JAK-STAT pathway and regulates lung epithelial cell proliferation
- Neuroimmunological Disorders: JAK In The Itch
- Neurological Symptoms In Essential Thrombocythemia: Impact Of JAK 2 V 617 F Mutation And Response To Therapy
- Neuroprotection of interleukin-6 against NMDA attack and its signal transduction by JAK and MAPK
- Neuroprotection of interleukin-6 against NMDA-induced neurotoxicity is mediated by Jak/Stat3, MAPK/ERK, and PI3K/AKT signaling pathways
- Neuroprotective effects of combined application of JAK-STAT signal pathway inhibitor and free radical scavenger on focal cerebral ischemia/reperfusion injury in rats
- New strategies for immunosuppression: interfering with cytokines by targeting the Jak/Stat pathway
- New-Generation JAK Inhibitors: How Selective Can They Be?
- News in cytogenetic and molecular diagnosis TEL-JAK-2 fusion as a model for hybrid oncogenes
- Next-Generation Sequencing Implicates Oncogenic Roles For P53 And Jak/Stat Signaling In Microcystic Adnexal Carcinomas
- N-glycosylation on lung cancer cell-secreted IL-6 prolongs its activation on Jak/Stat pathway
- Ngn3 expression during postnatal in vitro beta cell neogenesis induced by the Jak/Stat pathway
- Niche Signaling Promotes Stem Cell Survival In The Drosophila Testis Via The Jak–Stat Target Diap1
- Nickel Sulfate Promotes Il-17A Producing Cd4+ T Cells By An Il-23-Dependent Mechanism Regulated By Tlr4 And JAK-Stat Pathways
- Nicorandil And Theophylline Can Protect Experimental Rats Against Complete Freund’S Adjuvant-Induced Rheumatoid Arthritis Through Modulation Of Jak/Stat/Rankl Signaling Pathway
- Nilotinib Interferes With Cell Cycle, Abc Transporters And JAK-Stat Signaling Pathway In Cd34+/Lin-Cells Of Patients With Chronic Phase Chronic Myeloid …
- No evidence for JAK2 V617F mutation in colorectal cancer
- No Jak, No Receptor
- Nomination Of JAK-Stat Signalling As A Target For Ad Therapy Through Clinical And Molecular Informatics
- Non-autonomous crosstalk between the Jak/Stat and Egfr pathways mediates Apc1-driven intestinal stem cell hyperplasia in the Drosophila adult midgut
- Non-canonical Notch signaling activates IL-6/Jak/Stat signaling in breast tumor cells and is controlled by p53 and IKKα/IKKβ
- Non-Cscs Nourish Cscs Through Interleukin-17E-Mediated Activation Of Nf-Κb And Jak/Stat3 Signaling In Human Hepatocellular Carcinoma
- Noncytolytic clearance of sindbis virus infection from neurons by gamma interferon is dependent on Jak/Stat signaling
- Noonan Syndrome Peripheral Blood Cells Show Enhanced Spontaneous Colonies Growth In Vitro and Hyperactive JAK and RAS Intracellular Signalling Pathways
- Norovirus Replication In Human Intestinal Epithelial Cells Is Restricted By The Interferon-Induced Jak/Stat Signalling Pathway And Rna Polymerase Ii Mediated …
- Not4 enhances Jak/Stat pathway-dependent gene expression in Drosophila and in human cells
- Notch and Jak/Stat signaling pathways in breast carcinoma of luminal and basal/triple-negative immunophenotypes.
- Notch-induced hIL-6 production facilitates the maintenance of self-renewal of hCD34+ cord blood cells through the activation of JAK-PI3K-STAT3 pathway
- Novel 1, 4-Benzothazines Obliterate Cox-2 Mediated JAK-2/Stat-3 Signals With Potential Regulation Of Oxidative And Metabolic Stress During Colorectal Cancer
- Novel Antagonists Of The Sh2 Domain Of Grb2 Decrease Chronic Myeloid Leukemia (Cml) Cell Proliferation Via The Jak/Stat Pathway
- Novel Compounds Tad-1822-7-F2 And F5 Inhibited Hela Cells Growth Through The Jak/Stat Signaling Pathway
- Novel Cosic Resonance (Standing Wave) Solutions For Components Of The Jak–Stat Cellular Signaling Pathway: A Convergence Of Spectral Density Profiles
- Novel Fusion Proteins of Interferon α2b Cause Growth Inhibition and Induce JAK-STAT Signaling in Melanoma
- Novel Immunotherapeutic Activity Of JAK And Pi3Kδ Inhibitors In A Model Of Pancreatic Cancer
- JAK-STAT_PATHWAY_REGULATED_ANTIMICROBIAL_PEPTIDE-LIKE_GENE_LISTERICIN_HAS_BACTERIOCIDAL_ACTIVITY/links/0fcfd501b7c60c3b0e000000.pdf”>NOVEL JAK-STAT PATHWAY REGULATED ANTIMICROBIAL PEPTIDE-LIKE GENE LISTERICIN HAS BACTERIOCIDAL ACTIVITY
- Novel level of signalling control in the Jak/Stat pathway revealed by in situ visualisation of protein-protein interaction during Drosophila development
- Novel role for interleukin-2 receptor-JAK signaling in retrovirus transmission
- Novel Role of Jak/Stat3 Inhibitors in Overcoming Cisplatin Resistance in Squamous Carcinomas
- Novel Role of the JAK-STAT Pathway in Mediating the Effects of Atypical Antipsychotics on 5-HT2A Receptor Signaling
- Novel Secolignans From Peperomia Dindygulensis And Their Inhibitory Activities On JAK-Stat Signaling Pathways
- Novel shift of Jak/Stat signalling characterizes the protective effect of aurintricarboxylic acid (ATA) from tumor necrosis factor-α toxicity in human B lymphocytes
- Novel small molecular inhibitors disrupt the Jak/Stat3 and FAK signaling pathways and exhibit a potent antitumor activity in glioma cells
- Novel Therapies In Myeloproliferative Neoplasms (Mpn): Beyond JAK Inhibitors
- Novel-Targeted Therapy For Hematological Malignancies With JAK And Hdac Dual Inhibitors
- Ntrk2 Activation Cooperates With Pten Deficiency In T-All Through Activation Of Both The Pi3K–Akt And Jak–Stat3 Pathways
- Nutrition-regulated lipolysis in rainbow trout (Oncorhynchus mykiss) is associated with alterations in the ERK, PI3K-Akt, JAK-STAT, and PKC signaling pathways
- O016 Inhibition of the Jak/Stat pathway protects against neuroinflammation
- Obesity And Diabetes: Fxr And JAK Step Up To Bat
- Obituary: Professor JAK (John Charles) Kelly FRSN,(14 February 1928-11 February 2012)
- Obovatol Inhibits The Growth And Aggressiveness Of Tongue Squamous Cell Carcinoma Through Regulation Of The Egf‑Mediated Jak‑Stat Signaling Pathway
- Oct4 Accelerates Tumorigenesis Through Activating Jak/Stat Signaling In Ovarian Cancer Side Population Cells
- Oddziaływania Rośliny-Zwierzęta W Zmiennym Środowisku: JAK Lata Nasienne Oraz Depozycja Azotu Wpływają Na Populacje Konsumentów Oraz Na Roznoszenie I …
- Olfactory Ensheathing Cells Grafted Into The Retina Of Rcs Rats Suppress Inflammation By Down-Regulating The Jak/Stat Pathway
- Olive Secoiridoid Oleuropein And Its Semisynthetic Acetyl-Derivatives Reduce Lps-Induced Inflammatory Response In Murine Peritoneal Macrophages Via JAK-Stat And Mapks Signaling Pathways
- On Ek And JAK In Middle Norwegian: Mixed Methods In Historical Sociolinguistics
- On the Stochastic Modeling of the JAK-STAT Signal Transduction Pathway
- Oncostatin M, a cytokine released by activated mononuclear cells, induces epithelial cell-myofibroblast transdifferentiation via Jak/Stat pathway activation
- Oncostatin-M-Reactive Pericytes Aggravate Blood–Brain Barrier Dysfunction By Activating Jak/Stat3 Signaling In Vitro
- Op0029 Baricitinib, An Oral Janus Kinase (Jak) 1/Jak2 Inhibitor, In Patients With Active Rheumatoid Arthritis (Ra) And An Inadequate Response To Tnf Inhibitors: Results …
- Op0036 A Phase 3 Randomised, Placebo-Controlled, Double-Blind Study Of Upadacitinib (Abt-494), A Selective JAK-1 Inhibitor, In Patients With Active …
- Op0076 JAK-Inhibitors Tofacitinib And Baricitinib Improve Pathological Bone Loss In Vivo
- Op0156 Deciphering The In Vitro Therapeutic Potential Of JAK Inhibitors In Ankylosing Spondylitis
- Op0165 Joint-Specific Differences In The Activation Of The JAK-Stat Pathway In Rheumatoid Arthritis
- Open‐label study of oral CEP‐701 (lestaurtinib) in patients with polycythaemia vera or essential thrombocythaemia with JAK2‐V617F mutation
- Operační léčba hypospadie: kdy, JAK a kdo ji má provádět?
- Opportunities For Translation From The Bench: Therapeutic Intervention Of The Jak/Stat Pathway In Neuroinflammatory Diseases
- Opposing roles for Drosophila Jak/Stat signalling during cellular proliferation
- Optomotor-Blind Negatively Regulates Drosophila Eye Development By Blocking Jak/Stat Signaling
- Orf Virus Inhibits Interferon Stimulated Gene Expression And Modulates The Jak/Stat Signalling Pathway
- Organogenesis and tumorigenesis: Insight from the Jak/Stat pathway in the Drosophila eye
- Osmr Gene Effect On The Pathogenesis Of Chronic Autoimmune Urticaria Via The Jak/Stat3 Pathway
- Osthole Inhibits The Progression Of Human Gallbladder Cancer Cells Through Jak/Stat3 Signal Pathway Both In Vitro And In Vivo
- Osu-A9 Inhibits Pancreatic Cancer Cell Lines By Modulating P38-JAK-Stat3 Signaling
- Ovarian carcinoma cell inhibits T cell JAK-STAT signal transduction pathway, an experimental study
- Overexpression Inhibits Epithelial‐Mesenchymal Transition And Glomerulosclerosis In Rats With Chronic Kidney Disease By Inhibiting Jak/Stat Signaling Pathway
- Overexpression Of Agt Promotes Bronchopulmonary Dysplasis Via The Jak/Stat Signal Pathway
- Overexpression Of Alk4 Inhibits Cell Proliferation And Migration Through The Inactivation Of Jak/Stat3 Signaling Pathway In Glioma
- Over-expression of CKS1B activates both MEK/ERK and Jak/Stat3 signaling pathways and promotes myeloma cell drug-resistance
- Overexpression of c-Met and of the transducers PI3K, FAK and JAK in breast carcinomas correlates with shorter survival and neoangiogenesis
- Over-Expression Of Cyclin D1 Promotes Nscs Proliferation And Induces The Differentiation Into Astrocytes Via JAK-Stat3 Pathways
- Overexpression Of Il-11 Promotes Premalignant Gastric Epithelial Hyperplasia In Isolation From Germline Gp130-JAK-Stat Driver Mutations
- Overexpression Of Microrna-495 Improves The Intestinal Mucosal Barrier Function By Targeting Stat3 Via Inhibition Of The Jak/Stat3 Signaling Pathway In A Mouse …
- Overexpression Of Mir‑574‑3P Suppresses Proliferation And Induces Apoptosis Of Chronic Myeloid Leukemia Cells Via Targeting Il6/Jak/Stat3 Pathway
- Overexpression Of Rpn2 Promotes Osteogenic Differentiation Of Hbmscs Through The Jak/Stat3 Pathway
- Overexpression of tissue factor in cancer cells inhibits chemotherapy-induced apoptosis by activating Bcl-2 expression through the Jak/Stat5 pathway
- Oxidative stress blocks activation of JAK–STAT signaling in cardiac myocytes
- Oxidative stress inhibits carcinoma cell number through a non-apoptotic but JAK-dependent pathway
- Oxidative stress inhibits IFN-α-induced antiviral gene expression by blocking the JAK–STAT pathway
- Oxidative Stress-Induced Il-15 Trans-Presentation In Keratinocytes Contributes To Cd8+ T Cells Activation Via JAK-Stat Pathway In Vitiligo
- P057 Il-6 Induces Nlrp3 Inflammasome Activation Through Jak/Stat3-Dependent Nox2 Induction In Colon Epithelial Cells
- P105 Biologic/JAK Preference In Different Ibd Patient Types
- P113: Regulatory Role Of The JAK-Stat Signaling System On Pannus Formation And Mechanism Of Action Of Tofacitinib In Psoriatic Arthritis
- JAK-stat-signaling-tofacitinib/245/01337112″>P118 Balancing Jak/Stat-Signaling With Tofacitinib In Monocytes Of Healthy Controls And Ibd Patients
- P139 Continuous exposure to PEG-IFN-Alpha only transiently activates JAK-stat signalling in human liver
- P27 The Combined Use Of Anti-Egfr And Anti-Jak/Stat-3 Agents As Radiosensitizers In Hpv Negative And Positive Head And Neck Cancer Cell Lines
- P-362: Regulation of the renin-angiotensin system by Jak/Stat pathway
- P-375: Attenuation of cardiac hypertrophy in vivo by interference with the Jak/Stat pathway
- P38B And JAK-Stat Signaling Protect Against Invertebrate Iridescent Virus 6 Infection In Drosophila
- P4-125: JAK-STAT signaling pathway mediates astrogliosis in brains of scrapie-infected mice
- p42/p44-MAPK and PI3K are sufficient for IL-6 family cytokines/gp130 to signal to hypertrophy and survival in cardiomyocytes in the absence of Jak/Stat …
- P43 Induces Ip-10 Expression Through The JAK-Stat Signaling Pathway In Hmec-1 Cells
- P5363 A Novel Non-Hypoxic And Sex-Biased Mechanism Of Hif-1Alpha In Human Aortic Valve Interstitial Cells: Crosstalk Between JAK-Stat And Tlr Pathways
- Pairing JAK With Mek For Improved Therapeutic Efficiency In Myeloproliferative Disorders
- Pancreatitis-associated protein I suppresses NF-κB activation through a Jak/Stat-mediated mechanism in epithelial cells
- Paracrine signaling through the Jak/Stat pathway activates invasive behavior of ovarian epithelial cells in Drosophila
- Paracrine Unpaired Signaling through the Jak/Stat Pathway Controls Self-renewal and Lineage Differentiation of Drosophila Intestinal Stem Cells
- PART I JAK PROTEIN TYROSINE KINASES
- Partial restoration of B cell development in Jak‐3–/– mice achieved by co‐expression of IgH and Eµ‐myc transgenes
- Particular Role Of Jak/Stat3 Signaling In Functional Control Of Mesenchymal Progenitor Cells
- Pathophysiology defined by altered signal transduction pathways: the role of JAK-STAT and PI3K signaling in leukemic large granular lymphocytes
- Patterning Of Tissue Stress Responses By Jnk And Jak/Stat
- Patterning: JAK-STAT signalling in the Drosophila follicular epithelium
- Pd‐L1 Expression Is Mainly Regulated By Interferon Gamma Associated With Jak‐Stat Pathway In Gastric Cancer
- Pd-L1 Induced By Ifn-Γ From Tumor-Associated Macrophages Via The Jak/Stat3 And Pi3K/Akt Signaling Pathways Promoted Progression Of Lung Cancer
- Pegylated IFN-α regulates hepatic gene expression through transient Jak/Stat activation
- Pegylating IFNs at His-34 Improves the in Vitro Antiviral Activity Through the Jak/Stat Pathway
- Peracetylated Hydroxytyrosol, A New Hydroxytyrosol Derivate, Attenuates Lps-Induced Inflammatory Response In Murine Peritoneal Macrophages Via Regulation Of Non-Canonical Inflammasome, Nrf2/Ho1 And Jak/Stat Signaling Pathways
- Perianal Crohn’S Disease Is Associated With Distal Colonic Disease, Stricturing Disease Behavior, Ibd-Associated Serologies And Genetic Variation In The JAK-Stat …
- Peripheral but not central axotomy induces changes in Janus kinases (JAK) and signal transducers and activators of transcription (STAT)
- Peroxynitrite mediates glomerular lesion of diabetic rat via Jak/Stat signaling pathway
- Perspective: Targeting The Jak/Stat Pathway To Fight Age-Related Dysfunction
- Perturbed IFN-γ-JAK-signal transducers and activators of transcription signaling in tuberous sclerosis mouse models: synergistic effects of rapamycin-IFN-γ treatment
- Pharmaceutical intervention in the Jak/Stat signaling pathway
- Pharmacological Preconditioning With Phosphodiestrase Inhibitor: An Answer To Stem Cell Survival Against Ischemic Injury Through Jak/Stat Signaling
- Pharmacology And Therapeutics JAK-Stat Signaling Pathway Inhibition: A Role For Treatment Of Discoid Lupus Erythematosus And Dermatomyositis
- Pharmacology, Efficacy And Safety Of JAK Inhibitors In Crohn’S Disease
- Phosphoinositide 3-Kinase/Protein Kinase B (Pi3K/Akt) And Janus Kinase/Signal Transducer And Activator Of Transcription (Jak/Stat) Follicular Signalling Is Conserved …
- Phosphoproteome Profiling Reveals Critical Role Of JAK-Stat Signaling In Maintaining Chemoresistance In Breast Cancer
- Phosphoproteomic Analyses Of Interleukin 2 Signaling Reveal Integrated JAK Kinase-Dependent And-Independent Networks In Cd8+ T Cells
- Phosphorylation of STAT-3 in response to basic fibroblast growth factor occurs through a mechanism involving platelet-activating factor, JAK-2, and Src in human …
- Phosphospecific flow cytometry for pharmacodynamic drug monitoring: analysis of the JAK-STAT signaling pathway
- Photobiomodulation At 660 Nm Stimulates Proliferation And Migration Of Diabetic Wounded Cells Via The Expression Of Epidermal Growth Factor And The Jak/Stat …
- Photochemical preparation of a pyridone containing tetracycle: a JAK protein kinase inhibitor
- Physalin A Exerts Anti-Tumor Activity In Non-Small Cell Lung Cancer Cell Lines By Suppressing Jak/Stat3 Signaling
- Physical exercise attenuates age‐associated reduction in endothelium‐reparative capacity of endothelial progenitor cells by increasing CXCR4/JAK‐2 signaling in …
- Pi3K, P38 And Jak/Stat Signalling In Bronchial Tissue From Patients With Asthma Following Allergen Challenge
- PI3K/akt, Jak/Stat and MEK/ERK pathway inhibition protects retinal gaglion cells via different mechanisms after optic nerve injury
- PI3K/akt, Jak/Stat and MEK/ERK pathway inhibition protects retinal ganglion cells via different mechanisms after optic nerve injury
- PI3-kinase activation by GM-CSF in endothelium is upstream of Jak/Stat pathway: Role of αGMR
- Picrocrocin Exhibits Growth Inhibitory Effects Against Sk-Mel-2 Human Malignant Melanoma Cells By Targeting Jak/Stat5 Signaling Pathway, Cell Cycle Arrest …
- Pigment epithelium-derived factor inhibits high glucose-induced Jak/Stat signalling pathway activation in human glomerular mesangial cells
- PKCε is a permissive link in integrin-dependent IFN-γ signalling that facilitates JAK phosphorylation of STAT1
- PKD1 induces p21waf1 and regulation of the cell cycle via direct activation of the JAK-STAT signaling pathway in a process requiring PKD2
- Plasma growth hormone pulse activation of hepatic JAK-STAT5 signaling: developmental regulation and role in male-specific liver gene expression
- Pleiotrophin (PTN) is expressed in vascularized human atherosclerotic plaques: IFN-γ/Jak/Stat1 signaling is critical for the expression of PTN in macrophages
- Pleiotropy of the Drosophila JAK pathway cytokine Unpaired 3 in development and aging
- PMA activates Stat3 in the Jak/Stat pathway and induces SOCS5 in rat brain astrocytes.
- Po-046 Dual Inhibition Of JAK And Src: A Novel And Promising Therapeutic Combination For Pancreatic Cancer
- Polarized subcellular localization of Jak/Stat components is required for efficient signaling
- Poly I: C Facilitates The Phosphorylation Of Ctenopharyngodon Idellus Type I Ifn Receptor Subunits And JAK Kinase
- Polycystin‐1 Affects Cancer Cell Behaviour And Interacts With Mtor And JAK Signalling Pathways In Cancer Cell Lines
- Polycythemia vera and JAK-2 mutation in childhood: a case report
- Polycythemia Vera At JAK Age: Brief Analysis Of The Diagnosis After Its Introduction
- Polymorphisms in Jak/Stat signaling pathway genes and risk of non-Hodgkin lymphoma
- Polymorphisms in the Janus kinase 2 (JAK)/signal transducer and activator of transcription (STAT) genes: putative association of the STAT gene region with …
- Polyriboinosinic-Polyribocytidylic Acid Facilitates Interleukin-6, And Interleukin-8 Secretion In Human Dermal Fibroblasts Via The Jak/Stat3 And P38 Mapk Signal …
- Polyunsaturated fatty acids promote the expansion of myeloid‐derived suppressor cells by activating the Jak/Stat 3 pathway
- Population Pharmacokinetic Analysis Of Itacitinib, A Selective JAK-1 Inhibitor
- Porcine Reproductive And Respiratory Syndrome Virus Antagonizes Jak/Stat3 Signaling Via Nsp5, Which Induces Stat3 Degradation
- Porcine reproductive and respiratory syndrome virus Nsp1β inhibits interferon-activated Jak/Stat signal transduction by inducing karyopherin-α1 degradation
- Portal vein thrombosis as the first sign of a primary myeloproliferative disorder: diagnostic interest of the V617F JAK-2 mutation. A report of 2 cases.
- Possible Involvement Of The Jak/Stat Signaling Pathway In N-Acetylcysteine-Mediated Antidepressant-Like Effects
- Possible role of JAK-2 in attenuated cardioprotective effect of ischemic preconditioning in hyperhomocysteinemic rat hearts
- Possible role of the Jak/Stat pathways in the regulation of T cell-interferon related genes in systemic lupus erythematosus
- Postconditioning reduces infarct size and cardiac myocyte apoptosis via the opioid receptor and JAK-STAT signaling pathway
- Post-translational modifications in regulation of JAK-STAT pathway
- Potential Involvement Of The Il-6/Jak/Stat3 Pathway In The Pathogenesis Of Intervertebral Disc Degeneration
- Potential Role Of JAK-Stat Signaling Pathway In The Neurogenic-To-Gliogenic Shift In Down Syndrome Brain
- PP181. The role of the JAK-STAT pathways and SOCS in preeclampsia.
- Preassembly and ligand-induced restructuring of the chains of the IFN-γ receptor complex: the roles of JAK kinases, Stat1 and the receptor chains
- Prediction of genes regulated by JAK-STAT signal pathway
- Prediction of the structure of human Janus kinase 2 (JAK2) comprising JAK homology domains 1 through 7
- Predominant Activation Of Jak/Stat3 Pathway By Interleukin-6 Is Implicated In Hepatocarcinogenesis
- Preferential JAK-3 Mediated MUC8 Enhancement in Airway Epithelial Cells upon Th2 Cytokine Stimulus
- Pregabalin And Lacosamide Ameliorate Paclitaxel-Induced Peripheral Neuropathy Via Inhibition Of Jak/Stat Signaling Pathway And Notch-1 Receptor
- Preparation Of T-2-Glucoronide With Rat Hepatic Microsomes And Its Use Along With T-2 For Activation Of The Jak/Stat Signaling Pathway In Raw264. 7 Cells
- Preservative Treatment Of JAK (Artocarpus Heterophyllus) Sapwood Using Cca And Boron Preservatives
- PREVENTION OF ACUTE REJECTION WITH A NOVEL JANUS KINASE 3 (JAK-3) INHIBITOR IN A RODENT HETEROTOPIC CARDIAC ALLOGRAFT MODEL.
- Prevention of methamphetamine-induced microglial cell death by TNF-α and IL-6 through activation of the JAK-STAT pathway
- Prime Time for the Drosophila Jak/Stat Pathway
- Production and crystallization of recombinant JAK proteins
- Professor JAK (John Charles) Kelly FRSN (14 February 1928-11 February 2012)
- Profiling of dihydroorotate dehydrogenase, p38 and JAK inhibitors in the rat adjuvant‐induced arthritis model: a translational study
- Progenitor expansion in apc mutants is mediated by Jak/Stat signaling
- Progesterone activates J anus K inase 1/2 and activators of transcription 1 (JAK 1‐2/STAT 1) pathway in human spermatozoa
- Progestins induce transcriptional activation of signal transducer and activator of transcription 3 (Stat3) via a JAK-and Src-dependent mechanism in breast cancer cells
- Prognostic Significance Of JAK-Ii Gene Expression In Acute Myeloid Leukemia Patients: Pb1740
- Program/Abstract# 213 Drosophila apontic acts as a feedback inhibitor of Jak/Stat signaling and is required to limit an invasive cell population
- Progress In Research On Jak/Stat3 Signaling Pathway Regulating Tumor And Related Biological Functions
- Progress on Jak/Stats pathway and pathogenesis of obesity [J]
- Progress on JAK-STAT function in mammary gland.
- Progress on JAK-STAT signaling pathway in cancer research
- Progressive Down Regulation Of JAK-Stat, Cell Cycle, And Abc Transporter Genes In Cd34+/Lin-Cells Of Chronic-Phase Chronic Myeloid Leukemia (Cp-Cml) …
- Proinflammatory Cytokine Il-6 And JAK-Stat Signaling Pathway In Myeloproliferative Neoplasms
- Proinflammatory cytokine, Interleukin-6 (IL-6), promotes Interleukin-10 (IL-10) production from melanoma cell via Jak/Stat3 and Raf/ERK signal pathways
- Pro-inflammatory cytokine-induced SAPK/MAPK and Jak/Stat in rheumatoid arthritis and the new anti-depression drugs
- Prolactin concurrently activates src-PLD and Jak/Stat signaling pathways to induce proliferation while promoting differentiation in embryonic astrocytes
- Prolactin Receptor Coupling to JAK-Stat Pathways in Breast Cancer
- Prolactin-induced Jak2 phosphorylation of RUSH: A key element in Jak/RUSH signaling
- Prolactin-induced production of cytokines in macrophages in vitro involves Jak/Stat and JNK MAPK pathways
- Prolactin-induced production of reactive oxygen species and IL-1β in leukocytes from the bony fish gilthead seabream involves Jak/Stat and NF-κB signaling pathways
- Proliferative, Hyper-Migratory Phenotype And Jak/Stat Activation In Dermal Fibroblasts From Patients With Pulmonary Arterial Hypertension And Caveolin-1 Loss-Of …
- Promoter Methylation And Expression Of Socs3 Affect The Clinical Outcome Of Pediatric Acute Lymphoblastic Leukemia By Jak/Stat Pathway
- Promotes Brain-Derived Neurotrophic Factor And Hippocampal Neuron Proliferation To Alleviate Autism Symptoms Through Inhibition Of JAK-Stat Pathway By Lepr
- Promotes Hepatocyte Proliferation And Inhibits Apoptosis In Cecal Ligation And Puncture-Induced Sepsis Through The Jak/Stat Signaling Pathway By …
- Propofol Prevents Oxidative Stress And Apoptosis By Regulating Iron Homeostasis And Targeting Jak/Stat3 Signaling In Sh-Sy5Y Cells
- Proposal for an effective wastewater disposal system for JAK City in Cotonou (Benin Republic)
- Prosurvival role of Jak/Stat and Akt signaling pathways in MPP+-induced apoptosis in neurons
- Protection of curcumin against fructose-induced hyperuricaemia and renal endothelial dysfunction involves NO-mediated JAK–STAT signalling in rats
- Protective Effect Of Curcumin On Tnbs-Induced Intestinal Inflammation Is Mediated Through The Jak/Stat Pathway
- Protective effect of ginkgolide B against acute spinal cord injury in rats and its correlation with the Jak/Stat signaling pathway
- Protective Effect Of Hydrogen-Rich Saline On Pressure Overload-Induced Cardiac Hypertrophyin Rats: Possible Role Of JAK-Stat Signaling
- Protective effects of quercetin against oxidized LDL-induced apoptosis through p38 MAP kinase-dependent and JAK-responsive pathways in human endothelial cells
- Protective Efficacy Of Hippophae Rhamnoides L. Extract Exhibited In Rat Heart Against Hypobaric Hypoxia Is Possibly Mediated By Configurations In Jak/Stat Pathway
- Protective role of Jak/Stat signaling against renal fibrosis in mice with unilateral ureteral obstruction
- Protein ISGylation modulates the JAK-STAT signaling pathway
- Protein Kinase Kinase 2, A Novel E2-Interacting Protein, Promotes The Growth Of Classical Swine Fever Virus Via Attenuation Of The JAK-Stat Signaling Pathway”
- Protein kinases JAK and ERK mediate protective effect of interleukin-2 upon ganglion cells of the developing rat retina
- Protein Tyrosine Phosphatase Receptor Type Γ Is A JAK Phosphatase And Negatively Regulates Leukocyte Integrin Activation
- Protein tyrosine phosphatases in the Jak/Stat pathway
- Protein-tyrosine phosphatase PTPεC inhibits JAK-STAT signaling and differentiation induced by interleukin-6 and leukemia inhibitory factor in M1 leukemia cells
- Proteome Analysis Revealed Jak/Stat Signaling And Cytoskeleton Rearrangement Proteins In Human Lung Epithelial Cells During Interaction With Aspergillus Terreus
- Prr34‐As1 Overexpression Promotes Protection Of Propofol Pretreatment Against Ischemia/Reperfusion Injury In A Mouse Model After Total Knee Arthroplasty Via Blockade Of The Jak1‐Dependent Jak‐Stat Signaling Pathway
- PRSS14/Epithin is induced in macrophages by the IFN-γ/Jak/Stat pathway and mediates transendothelial migration
- Pruritus In Primary Myelofibrosis: Management Options In The Era Of JAK Inhibitors
- Przedsiębiorczość jako wartość dla organizacji i jednostki. JAK uczelnie mogą rozwijać postawy przedsiębiorcze wśród studentów
- Pulsatility of growth hormone (GH) signalling in liver cells: role of the JAK-STAT5b pathway in GH action
- Putative role of hepatitis B virus X protein in hepatocarcinogenesis: Effects on apoptosis, DNA repair, mitogen‐activated protein kinase and Jak/Stat pathways
- Pyridine (Phip) Induces Gene Expression Changes In Jak/Stat And Mapk Pathways Related To Inflammation, Diabetes And Cancer
- QS189. Thermal Injury Activates Myocardial JAK-STAT Signaling
- QS375. The Role of p38 in Fer Kinase Dependent Regulation of the Jak/Stat Pathway
- Qualitative and quantitative analysis of a Bio-PEPA model of the gp130/Jak/Stat signalling pathway
- Quantitative analysis of JAK binding using isothermal titration calorimetry and surface plasmon resonance
- Quantitative proteomic analysis reveals that transmissible gastroenteritis virus activates the JAK-STAT1 signaling pathway
- QUASI-STEADY STATE DYNAMICS OF IFN-γ INDUCED JAK-STAT SIGNAL TRANSDUCTION PATHWAY
- Quercetin affects leptin and its receptor in human gastric cancer MGC-803 cells and JAK-STAT pathway
- Quercetin and EGCG exhibit chemopreventive effects in cholangiocarcinoma cells via suppression of Jak/Stat signaling pathway
- JAK-stat3-signalling-pathway/8/00002413″>QUERCETIN INHIBITS IL-6/Jak/Stat3 SIGNALLING PATHWAY IN LIVER OF RATS WITH CIRRHOSIS INDUCED BY COMMON BILE DUCT LIGATION
- Quercetin, a flavonoid phytoestrogen, ameliorates experimental allergic encephalomyelitis by blocking IL-12 signaling through JAK-STAT pathway in T lymphocyte
- Radiation doses in mammography-As low as reasonably achievable; Dawka promieniowania w mammgrafii-tak niewielka, JAK to realnie mozliwe
- Rapamycin (Sirolimus)–induced protection against ischemia-reperfusion injury is mediated through AMPK, Akt and Jak/Stat pathways in mouse heart
- Rapid inhibition of MAPK signaling and anti-proliferation effect via Jak/Stat signaling by interferon-α in hepatocellular carcinoma cell lines
- Rapid Molecular Profiling Of Myeloproliferative Neoplasms Using Targeted Exon Resequencing Of 86 Genes Involved In JAK-Stat Signaling And Epigenetic …
- RAS signaling promotes resistance to JAK inhibitors by suppressing BAD-mediated apoptosis
- Reactive oxygen species regulate heat-shock protein 70 via the Jak/Stat pathway
- Real‐Time Pcr And Droplet Digital Pcr: Two Techniques For Detection Of The Jak2V617F Mutation In Philadelphia‐Negative Chronic Myeloproliferative Neoplasms
- JAK-inhibitors-2329-6631.1000e124.pdf”>Recent News in the Fast-Paced Field of JAK Inhibitors. J Develop Drugs 2: e124. doi: 10.4172/2329-6631.1000 e124 Page 2 of 2 Volume 2• Issue 2• 1000e124 …
- Recent patents of gene mutation relative to Jak/Stat pathway and their implication in myeloproliferative diseases
- Recent Progress And Perspective In JAK Inhibitors For Rheumatoid Arthritis: From Bench To Bedside
- Recent Progress In JAK Inhibitors For The Treatment Of Rheumatoid Arthritis
- Receptor expression is essential for proliferation induced by dimerized JAK kinases
- Receptor-mediated tobacco toxicity: cooperation of the Ras/Raf-1/MEK1/ERK and JAK-2/STAT-3 pathways downstream of α7 nicotinic receptor in oral keratinocytes
- Reconstructing the Jak/Stats signal pathway restored the anti-proliferative response of MHCC97 on interferon alpha
- Recurrent Somatic JAK-Stat Pathway Variants Within A Runx1-Mutated Pedigree
- Red Nucleus Interleukin‐1Β Evokes Tactile Allodynia Through Activation Of Jak/Stat3 And Jnk Signaling Pathways
- Red Nucleus Interleukin-6 Participates In The Maintenance Of Neuropathic Pain Through Jak/Stat3 And Erk Signaling Pathways
- Red Wine Polyphenol Extract Efficiently Protects Intestinal Epithelial Cells From Inflammation Via Opposite Modulation Of Jak/Stat And Nrf2 Pathways
- Reduced expression of JAK-1 and Tyk-2 proteins leads to interferon resistance in hepatitis C virus replicon
- Reduces Hepatic Lipid Accumulation In Yellow Catfish (Pelteobagrus Fulvidraco) And Modulates Lipogenesis And Lipolysis Via Ppara, JAK-Stat, And Ampk …
- Reduction of Lobe leads to TORC1 hypoactivation that induces ectopic Jak/Stat signaling to impair Drosophila eye development
- Regeneration of three layers vascular wall by using BMP2-treated MSC involving HIF-1α and Id1 expressions through Jak/Stat pathways
- Regulating RISK: a role for JAK-STAT signaling in postconditioning?
- Regulation of apoptosis by resveratrol through Jak/Stat and mitochondria mediated pathway in human epidermoid carcinoma A431 cells
- Regulation of circadian behavioral output via a MicroRNA-Jak/Stat circuit
- Regulation of inflammatory responses in tumor necrosis factor–activated and rheumatoid arthritis synovial macrophages by JAK inhibitors
- Regulation of interferon-inducible proteins by doxorubicin via IFNγ-JAK-STAT signaling in tumor cells
- Regulation of JAK kinases by intracellular leptin receptor sequences
- Regulation Of Jak/Stat Signal Pathway By Mir-21 In The Pathogenesis Of Juvenile Idiopathic Arthritis
- Regulation Of Jak/Stat Signalling By Endocytosis
- Regulation of Jak/Stat signalling by SOCS in the myocardium
- Regulation of JAK-STAT signaling through PKC-dependent pathway
- Regulation of JAK–STAT signalling in the immune system
- Regulation of macrophage-mediated chronic inflammation by JAK inhibitors
- Regulation of mitochondrial function by the members of Jak/Stat family
- Regulation of proliferation, cell competition, and cellular growth by the Drosophila JAK-STAT pathway
- Regulation of rat heme oxygenase-1 expression by interleukin-6 via the Jak/Stat pathway in hepatocytes
- Regulation of Rat Heme Oxygenase–1 Gene Expression by Interleukin–6 via Jak/Stat Pathway
- Regulation Of Stem Cell Properties Of Müller Glia By Jak/Stat And Mapk Signaling In The Mammalian Retina
- Regulation of the PML tumor suppressor in drug-induced senescence of human normal and cancer cells by Jak/Stat-mediated signaling
- Regulation Of Tnf-Α And Nf-Κb Activation Through The Jak/Stat Signaling Pathway Downstream Of Histamine 4 Receptor In A Rat Model Of Lps-Induced Joint …
- Regulatory Effect Of Anti-Gp130 Functional Mab On Il-6 Mediated Rankl And Wnt5A Expression Through JAK-Stat3 Signaling Pathway In Fls
- Regulatory Role Of The JAK Stat Kinase Signalling System On The Il-23/Il-17 Cytokine Axis In Psoriatic Arthritis
- Regulatory T Cell Frequencies In Patients With Rheumatoid Arthritis Are Increased By Conventional And Biological Dmards But Not By JAK Inhibitors
- Relationship Between Her2 And Jak/Stat-Socs3 Signaling Pathway And Clinicopathological Features And Prognosis Of Ovarian Cancer
- Remifentanil preconditioning confers cardioprotection via the Jak/Stat but not PI3K/Akt pathway in rats
- Remote Ischaemic Preconditioning Activates The JAK-Stat Pathway Resulting In The Attenuation Of Egr-1 Expression Following Myocardial Ischaemia Reperfusion Injury
- Remote Ischemic Preconditioning Attenuates Egr-1 Expression Following Myocardial Ischemia Reperfusion Injury Through Activation Of The JAK-Stat Pathway
- Remote Limb Ischaemic Postconditioning Protects Against Myocardial Ischaemia/Reperfusion Injury In Mice: Activation Of Jak/Stat3-Mediated Nrf2-Antioxidant …
- Renovascular Hypertension Associated With JAK 2 V617F Positive Myeloproliferative Neoplasms Treated With Angioplasty: 2 Cases And Literature Review
- Repeat Exposure To Polyinosinic: Polycytidylic Acid Induces Tlr3 Expression Via JAK-Stat Signaling And Synergistically Potentiates Nfκb-Rela Signaling In Arpe-19 …
- Reply to ‘Absence of JAK-2 (Val617Phe) point mutations in multiple myeloma’by Dr Qin Huang et al. referred to ‘Screening of JAK2 V617F mutation in multiple …
- Repression of c-Cbl leads to enhanced G-CSF JAK-STAT signaling without increased cell proliferation
- Repression of Wasp by Jak/Stat signalling inhibits medial actomyosin network assembly and apical cell constriction in intercalating epithelial cells
- Requirement for both JAK-mediated PI3K signaling and ACT1/TRAF6/TAK1-dependent NF-κB activation by IL-17A in enhancing cytokine expression in human airway …
- Requirement for Jak/Stat signaling throughout border cell migration in Drosophila
- Requirement Of Leukemia Inhibitory Factor Or Epidermal Growth Factor For Pre-Implantation Embryogenesis Via Jak/Stat3 Signaling Pathways
- Research Of Resveratrol Regulating Jak/Stat Signaling Pathway In The Treatment Of Atherosclerotic Rats
- Research on JAK and STAT1 pathway in bleomycin-induced pulmonary fibrosis rats
- Research Progress Of Jak/Stat Signal Transduction Pathway And Traditional Chinese Medicine Intervention In The Treatment Of Ischemic Stroke
- Research Progress Of JAK-3 Kinase And Its Inhibitors
- Research Progress On Effect Of JAK Inhibitors On Myelofibrosis-Review
- Research progress on Jak/Stat signaling pathway and the inhibitor AG490 in lymphoma
- Respirovirus C Protein Inhibits Activation Of Type I Interferon Receptor‐Associated Kinases To Block Jak‐Stat Signaling
- Response Of The JAK-Stat Pathway To Mammalian Hibernation In 13-Lined Ground Squirrel Striated Muscle
- Response Of The JAK-Stat Signaling Pathway To Oxygen Deprivation In The Red Eared Slider Turtle, Trachemys Scripta Elegans
- Response To:’Regulatory Role Of The JAK Stat Kinase Signalling System On The Il-23/Il-17 Cytokine Axis In Psoriatic Arthritis’ By Raychaudhuri Et Al
- Restoring The Long Noncoding Rna Meg3 Indicates A Potential Role For JAK-Stat Signaling In Chronic Myeloid Leukemia
- Results of COMFORT-I, a randomized double-blind phase III trial of JAK 1/2 inhibitor INCB18424 (424) versus placebo (PB) for patients with myelofibrosis (MF).
- Resveratrol Inhibits Myeloid Leukemia Cell Lines With JAK2V617F Via Both Inactivation Of The Jak/Stat Pathway and Upregulation Of The ERK Pathway
- Resveratrol modulates cytokine-induced Jak/Stat activation more efficiently than 5-aminosalicylic acid: an in vitro approach
- Resveratrol Protects Hippocampal Neurons Against Cerebral Ischemia-Reperfusion Injury Via Modulating Jak/Erk/Stat Signaling Pathway In Rats
- RET-familial medullary thyroid carcinoma mutants Y791F and S891A activate a Src/Jak/Stat3 pathway, independent of glial cell line–derived neurotrophic factor
- Retinal Axon Guidance Requires Integration Of Eya And The Jak/Stat Pathway Into Phosphotyrosine-Based Signaling Circuitries In Drosophila
- Retinoic Acid Amide Inhibits Jak/Stat Pathway In Lung Cancer Which Leads To Apoptosis
- Retraction Note: Inhibition of constitutively active JAK-Stat pathway suppresses cell growth of human T-cell leukemia virus type 1-infected T-cell lines and primary adult …
- Reverse phase protein microarray for identification of IL6 receptor ligation-induced insulin receptor, PI3K/AKT, and Jak/Stat signaling pathways in the CARD11 …
- Reversed expression of the Jak/Stat pathway related proteins prolactin receptor and STAT5a in normal and abnormal breast epithelial cells
- Rheumatoid Arthritis: JAK-Ing Up Inadequate Ra Therapy
- Rho family GTPases are required for activation of Jak/Stat signaling by G protein-coupled receptors
- Rhododendron Album Blume Extract Inhibits Tnf-Α/Ifn-Γ-Induced Chemokine Production Via Blockade Of Nf-Κb And Jak/Stat Activation In Human Epidermal …
- Ring-Finger Protein 6 Amplification Activates Jak/Stat3 Pathway By Modifying Shp-1 Ubiquitylation And Associates With Poor Outcome In Colorectal Cancer
- Roadside Geology of…-czyli JAK najłatwiej zwiedzać geoturystyczne atrakcje Ameryki Północnej
- Robustness analysis of the IFN-γ induced JAK-STAT signaling pathway
- Robustness And Information Transfer Within Il-6-Induced Jak/Stat Signalling
- Robustness of the signal transduction system of the mammalian Jak/Stat pathway and dimerization steps
- Robustness of the signal transduction system of the mammalian Jak/Stat pathway and dimerization steps.(Theory of Bio-Mathematics and Its Applications)
- Roflumilast N-oxide prevents cytokine secretion induced by cigarette smoke combined with LPS through Jak/Stat and ERK1/2 inhibition in airway epithelial …
- Role for histone deacetylases in regulating angiotensinogen expression mediated by the JAK-STAT pathway by suppressor of cytokine signaling in renal proximal …
- Role of downstream signaling events of interleukin-6 triggered Jak/Stat3 and PI3K/AKT signaling pathways in the development of resistance to dexamethasone by …
- Role Of Genes In The JAK-Stat Pathway In The Innate Immune System And Immunosenescence In Drosophila Melanogaster
- Role of interleukin-6 signaling via the Jak/Stat pathway in human myeloma and effects on mediators of cell survival and proliferation
- Role of JAK and STAT Pathway Activation on the High Glucose-induced Transdifferentiation in Renal Proximal Tubular Epithelial Cells
- Role Of JAK In The Induction Of Inos In Macrophages Using Pharmacological Inhibitors
- Role Of JAK Inhibitors And Immune Cells In Transplantation
- Role of JAK kinases and STATs in cytokine signal transduction
- Role of Jak/Stat in intestinal injury induced by intestinal ischemia/reperfusion in rats
- Role Of Jak/Stat Pathway In Cardioprotection Of Remote Ischemic Preconditioning
- Role Of Jak/Stat Pathway In Cerebral Ischemia Injury
- Role of Jak/Stat pathway in IL-6-induced activation of vascular smooth muscle cells
- Role of Jak/Stat signal pathway on the secretion of proinflammatory cytokines by pancreatic elastase-induced rat Kupffer cells
- Role of Jak/Stat signaling in neuroepithelial stem cell maintenance and proliferation in the Drosophila optic lobe
- Role Of Jak/Stat3 Signaling In Functional Stimulation Of Mesenchymal Progenitor Cells By Fibroblast Growth Factor
- Role Of Jak/Stat3 Signaling In Functional Stimulation Of Mesenchymal Progenitor Cells With Alkaloid Songorine
- Role Of JAK-Stat Pathway
- Role Of JAK-Stat Pathway In Cancer Signaling
- Role of JAK-STAT pathway in pulmonary fibrosis
- Role Of JAK-Stat Pathway In Reducing Cardiomyocytes Hypoxia/Reoxygenation Injury Induced By S1P Postconditioning
- Role Of JAK-Stat Signaling In Maturation Of Phagosomes Containing Staphylococcus Aureus
- Role of JAK-STAT signaling in the interstitial fibrosis of unilateral ureter obstruction mice
- Role of JAK-STAT signaling in the pathogenesis of myeloproliferative disorders
- Role Of JAK-Stat Signalling On Motor Function Recovery After Spinal Cord Injury
- Role of JAK-STAT3 signaling pathway during neuronal differentiation of rat bone marrow mesenchymal stem cells**⋆
- Role of NAD (P) H oxidase in angiotensin II–induced Jak/Stat signaling and cytokine induction
- Role Of Notch And Jak/Stat Signaling Pathways In Acute Megakaryoblastic Leukemia
- Role of receptor for advanced glycation end‐product (RAGE) and the Jak/Stat‐signaling pathway in AGE‐induced collagen production in NRK‐49F cells
- Role Of Socs 3 In The Jak/Stat3 Pathway In The Human Placenta: Different Mechanisms For Preterm And Term Labor
- Role of suppressor of cytokine signaling in the regulation of negative feedback in the Jak/Stat signaling pathway
- Role of the Jak/Stat pathway in proximo-distal patterning of Drosophila appendages
- Role of the Jak/Stat pathway in rat carotid artery remodeling after vascular injury
- Role of the Jak/Stat pathway in the regulation of interleukin-8 transcription by oxidized phospholipids in vitro and in atherosclerosis in vivo
- Role of the Jak/Stat signal transduction pathway in the regulation of gene expression in CNS
- Role of the Jak/Stat signaling pathway in diabetic nephropathy
- Role Of The Jak/Stat Signaling Pathway In Regulation Of Innate Immunity In Neuroinflammatory Diseases
- JAK-STAT-signaling-pathway-in-Systemic-Sclerosis.pdf”>Role Of The Jak/Stat Signaling Pathway In Systemic Sclerosis
- Role of the Jak/Stat signaling pathway in the pathogenesis of acute myocardial infarction in rats and its effect on NF-κB expression
- Role of the JAK–STAT pathway in myocardial injury
- Role of the JAK-STAT pathway in PDGF-stimulated proliferation of human airway smooth muscle cells
- Role of the JAK-STAT pathway in proliferation and differentiation of human hypertrophic scar fibroblasts induced by connective tissue growth factor
- Role of the JAK–STAT pathway in protection against myocardial ischemia/reperfusion injury
- Role of the JAK-STAT pathway in protection of hydrogen peroxide preconditioning against apoptosis induced by oxidative stress in PC12 cells
- Role Of The JAK-Stat Signal Pathway Disturbances In The Development Of Primary Immune Deficiencies.
- Role of the JAK‐STAT Signalling Pathway in Cancer
- Role of the STAT1 pathway in apoptosis induced by fludarabine and JAK kinase inhibitors in B-cell chronic lymphocytic leukemia
- Roles for the interleukin-4 receptor and associated Jak/Stat proteins in human articular chondrocyte mechanotransduction
- Roles of oncostatin M and Jak/Stat pathway in myoblast differentiation, skeletal muscle regeneration, and skeletal muscle hypertrophy
- Roles of PI3K and JAK pathways in viability of retinal ganglion cells after acute elevation of intraocular pressure in rats with different autoimmune backgrounds
- Roles of PI3K/Akt and Jak/Stat signal transduction pathways in reduction of myocardial ischemia/reperfusion injury by postconditioning with α7nAChR agonist in rats
- Roles of the JAK pathway in Follicular Patterning in Drosophila
- Roles of the JAK-STAT signaling pathways in rheumatoid arthritis
- Rosuvastatin treatment activates JAK-STAT pathway and increases efficacy of allogeneic mesenchymal stem cell transplantation in infarcted hearts
- Rozhovor Britských Listů 100. JAK Odložení A Nespolehliví Komunisté V Literárkách Podvraceli Režim [Britské Listy Interview 100. How Unreliable And Discarded …
- Runx1 promotes the development of glioma cells by regulating JAK-STAT signalling pathway
- S14-95, a novel inhibitor of the Jak/Stat pathway from a Penicillium species
- S80 Mesenchymal Stromal Cells (Msc) Modulate Human Macrophages In Acute Respiratory Distress Syndrome (Ards) Via Secretion Of Extracellular Vesicles (Ev) Which Enhance Oxidative Phosphorylation And Regulate Jak/Stat Signalling
- Sadrudin A. Ahmed And JAK Jabes, University Of Ottawa
- Safety and efficacy of CYT387, a JAK-1/2 inhibitor, for the treatment of myelofibrosis.
- SAHA down-regulates the expression of indoleamine 2, 3-dioxygenase via inhibition of the Jak/Stat1 signaling pathway in gallbladder carcinoma cells
- Salvianolic acid B suppresses IFN-γ-induced Jak/Stat1 activation in endothelial cells
- Salvianolic Acids Enhance Cerebral Angiogenesis And Neurological Recovery By Activating JAK 2/Stat 3 Signaling Pathway After Ischemic Stroke In Mice
- Sat0013 Molecular And Cellular Repsonses To Inhibition Of JAK-Stat Signalling In Ra Synovial Fibroblasts And Whole Tissue Explants
- Sat0088 Anti-JAK Is Anti-Fibrotic In Patients With Rheumatoid Arthritis
- Sat0236 Long-Term Safety And Efficacy Of Upadacitinib (Abt-494), An Oral JAK-1 Inhibitor In Patients With Rheumatoid Arthritis In An Open Label Extension Study
- Sat0639 Active Jak/Stat Signaling In Circulating Leucocytes Defines Distinct Immunologic Endotypes Of Rheumatoid …
- Scoping Review On The Use Of Drugs Targeting Jak/Stat Pathway In Atopic Dermatitis, Vitiligo, And Alopecia Areata
- Screening Active Compounds From Garcinia Species Native To China Reveals Novel Compounds Targeting The Stat/JAK Signaling Pathway
- Screening For Venous Thrombosis In Young Myeloproliferative Neoplasms And Impact Of JAK 2 Allele Burden On Its Incidence: Egyptian Experience
- Secreted Vago restricts West Nile virus infection in Culex mosquito cells by activating the JAK-STAT pathway
- Selective Immunomodulation Of Inflammatory Pathways In Keratinocytes By The Janus Kinase (Jak) Inhibitor Tofacitinib: Implications For The Employment Of JAK-Targeting Drugs In Psoriasis
- Selective Interference Targeting Of Lnk In Umbilical Cord‐Derived Late Endothelial Progenitor Cells Improves Vascular Repair, Following Hind Limb Ischemic Injury, Via Regulation Of Jak2/Stat3 Signaling
- Selective JAK inhibitors
- Selective JAK inhibitors in development for rheumatoid arthritis
- Selective Jak/Stat3 signalling regulates transcription of colony stimulating factor-2 and-3 in Concanavalin-A-activated mesenchymal stromal cells
- Selective Stimulation Of The Jak/Stat Signaling Pathway By Silica Nanoparticles In Human Endothelial Cells
- Selective Targeting Of Jak/Stat Signaling Is Potentiated By Bcl-Xl Blockade In Il-2–Dependent Adult T-Cell Leukemia
- Selectively Induces Apoptosis In Cutaneous T-Cell Lymphoma Cells Via Activating Pro-Apoptotic Integrated Stress Response And Inactivating Jak/Stat And Nf …
- Sensitization of IFN-γ JAK-STAT signaling during macrophage activation
- Series introduction: JAK-STAT signaling in human disease
- Serine 249 Phosphorylation And Pin1-Induced Isomerization Activate Mutant P53 R249S Gain-Of-Function And Promote Cross-Talk With Jak/Stat1 Signalling In …
- Setaria digitata secreted filarial lipids modulate IL-12 signaling through JAK-STAT pathway leading to the development of Th1 response
- Several Genes Involved In The JAK-Stat Pathway May Act As Prognostic Markers In Pancreatic Cancer Identified By Microarray Data Analysis
- Sevoflurane Inhibits Glutamate-Aspartate Transporter And Glial Fibrillary Acidic Protein Expression In Hippocampal Astrocytes Of Neonatal Rats Through The Janus Kinase/Signal Transducer And Activator Of Transcription (Jak/Stat) Pathway
- Sevoflurane Postconditioning Reduces Apoptosis By Activating The JAK-Stat Pathway After Transient Global Cerebral Ischemia In Rats
- SH2-B family members differentially regulate JAK family tyrosine kinases
- SH2B3 (LNK) mutations from myeloproliferative neoplasms patients have mild loss of function against wild type JAK2 and JAK2 V617F
- Short-type PB-cadherin promotes survival of gonocytes and activates JAK-STAT signalling
- Should myeloid and lymphoid neoplasms with PCM1‐JAK2 and other rearrangements of JAK2 be recognized as specific entities?
- SHP‐1 suppresses cancer cell growth by promoting degradation of JAK kinases
- Shp‐2 Contributes To Anti‐Rsv Activity In Human Pulmonary Alveolar Epithelial Cells By Interfering With The Ifn‐Α‐Induced Jak/Stat1 Pathway
- Shrimp With Knockdown Of Lvsocs2, A Negative Feedback Loop Regulator Of Jak/Stat Pathway In Litopenaeus Vannamei, Exhibit Enhanced Resistance Against Wssv
- Signal regulatory protein α ligation induces macrophage nitric oxide production through Jak/Stat-and phosphatidylinositol 3-kinase/Rac1/NAPDH oxidase/H2O2 …
- Signal Transduction Pathways in Development: the Jak/Stat Pathway
- Signal Transduction Through JAK-Stat And Nf-Κb Regulated Pim-1 Kinase: Novel Target For Anticancer Leads
- Signaling events leading to the curative effect of cystatin on experimental visceral leishmaniasis: Involvement of ERK1/2, NF‐κB and Jak/Stat pathways
- Signaling role of hemocytes in Drosophila Jak/Stat-dependent response to septic injury
- Signaling Through gp130 and the Jak/Stat Pathway Play a Role in Intravitreous Neovascularization and VEGF Expression in the OIR Rat Model
- Signaling through the Jak/Stat pathway, recent advances and future challenges
- Signaling through the JAK-Stat pathway: Regulation of tyrosine kinase activity
- Signaling Via The Cytor/Jak/Stat/Socs Pathway: Emergence During Evolution
- Significance of ERK cascade compared with Jak/Stat and PI3-K pathway in gp130-mediated cardiac hypertrophy
- Significance Of Il28Ra In Diagnosis Of Early Pancreatic Cancer And Its Regulation To Pancreatic Cancer Cells By Jak/Stat Signaling Pathway–Effects Of Il28Ra …
- Significant inhibition of TRAIL-mediated fibroblast-like synovial cell apoptosis by IFN-γ through Jak/Stat pathway by translational regulation
- Silencing Microrna‐221/222 Cluster Suppresses Glioblastoma Angiogenesis By Suppressor Of Cytokine Signaling‐3‐Dependent Jak/Stat Pathway
- Silencing of negative regulator of Jak/Stat in colorectal cancer
- Silencing of SOCS-3, a Jak/Stat pathway regulator, by promoter hypermethylation in mesothelioma
- Simvastatin attenuates hypertrophic responses induced by cardiotrophin-1 via JAK–STAT pathway in cultured cardiomyocytes
- Simvastatin Prevents Cardiac Hypertrophy In A Rat Model Via Modulation Of The Jak/Stat Pathway
- Simvastatin prevents cardiac hypertrophy in vitro and in vivo via Jak/Stat pathway
- Simvastatin Prevents Isoproterenol-Induced Cardiac Hypertrophy Through Modulation Of The Jak/Stat Pathway
- Single-cell, phosphoepitope-specific analysis demonstrates cell type-and pathway-specific dysregulation of Jak/Stat and MAPK signaling associated with in vivo …
- Sitagliptin Attenuates Cardiomyopathy By Modulating The Jak/Stat Signaling Pathway In Experimental Diabetic Rats
- Site of pegylation and polyethylene glycol molecule size attenuate interferon-α antiviral and antiproliferative activities through the Jak/Stat signaling pathway
- Small Molecule Chemosensitizing Agents: Polo-Like Kinase 1 (Plk1), Braf And Janus Kinase (Jak) Inhibitors
- Small Molecule Inhibitors of NF- B and Jak/Stat Signal Transduction Pathways as Promising Anti-Inflammatory Therapeutics
- Snapshot: JAK-stat signaling
- S-Nitrosocaptopril Interrupts Adhesion Of Cancer Cells To Vascular Endothelium By Suppressing Cell Adhesion Molecules Via Inhibition Of The Nf-Кb And Jak/Stat Signal Pathways In Endothelial Cells
- SOCS negative regulation of the JAK-STAT pathway
- SOCS regulation of the Jak/Stat signalling pathway
- SOCS1 and SHP1 hypermethylation in mantle cell lymphoma and follicular lymphoma: implications for epigenetic activation of the Jak/Stat pathway
- SOCS1 gene transfer accelerates the transition to heart failure through the inhibition of the gp130/Jak/Stat pathway
- Socs-1 Inhibits Proliferation Of Ovarian Cancer Cell Lines By Regulating Jak/Stat3 Pathway And P53
- SOCS‐1 suppresses TNF‐α‐induced apoptosis through the regulation of JAK activation
- SOCS-1, a negative regulator of the Jak/Stat pathway, is silenced by methylation in human hepatocellular carcinoma and shows growth-suppression activity
- SOCS-1,-3 gene delivery in gastric cancer cells induces a potent anti-proliferative effect via the suppression of Jak/Stat and P38 MAPK signaling pathways
- Socs3 Regulates Mucus Hypersecretion Via Jak/Stat Signal Pathway
- SOCS36E, a novel Drosophila SOCS protein, suppresses Jak/Stat and EGF-R signalling in the imaginal wing disc
- SOCS3-mediated blockade of Jak/Stat3 signaling pathway reveals its major contribution to spinal cord neuroinflammation and mechanical allodynia after peripheral …
- Socs-JAK-Stat Signalling Is Involved In The Beneficial Effects Of Aerobic Exercise In A Model Of Hdm-Induced Asthma
- Socs-Regulation Of Jak/Stat Signalling In Idiopathic Pulmonary Fibrosis (Ipf)
- Solanum Nigrum Unripe Fruit Fraction Attenuates Adriamycin Resistance By Down-Regulating Multi-Drug Resistance Protein (Mdr)-1 Through JAK-Stat Pathway
- Somatic control of germline sexual development is mediated by the Jak/Stat pathway
- Somatic JAK-2 V617F Mutational Analysis In Polycythemia Rubra Vera: A Tertiary Care Center Experience
- Somatic JAK-Stat Mutations In Subtypes Of Aggressive B-Cell Lymphomas With Dlbcl Morphology
- Sophoraflavanone G From Sophora Alopecuroides Inhibits Lipopolysaccharide-Induced Inflammation In Raw264. 7 Cells By Targeting Pi3K/Akt, Jak/Stat And Nrf2/Ho …
- Sophoraflavanone G Fromsophora Alopecuroidesinhibits Lipopolysaccharide-Induced Inflammation In Raw264. 7 Cells By Targeting Pi3K/Akt, Jak/Stat And Nrf2/Ho-1 …
- Sos1, Arhgef1, And Dock2 Rho-Gefs Mediate JAK-Dependent Lfa-1 Activation By Chemokines
- South Carolina’s Everyman Artist: The Oscar Jackson “Jak” Smyrl, Jr., Papers
- Spatiotemporal Control Of Interferon-Induced Jak/Stat Signalling And Gene Transcription By The Retromer Complex
- Spatiotemporal Regulation Of Cell Fusion By Jnk And Jak/Stat Signaling During Drosophila Wound Healing
- Sphingosine 1 Phosphate Mediates Cardiac Fibrosis Through Jak/Stat Signalling Pathways
- Splanchnic vein thrombosis, the onset manifestation in JAK positive chronic myeloproliferative disorders neoplasms
- Stability analysis of a time delay model for the JAK-STAT signalling pathway
- Stachydrine Ameliorates Isoproterenol-Induced Cardiac Hypertrophy And Fibrosis By Suppressing Inflammation And Oxidative Stress Through Inhibiting Nf-Κb And Jak/Stat Signaling Pathways In Rats
- Stam Interaction With Hrs Controls Jak/Stat Activation By Interferon-Α At The Early Endosome
- Stat 5B, Activated by Insulin in a JAK-Independent Fashion, Plays a Role in Glucokinase Gene Transcription
- Staurosporine induces megakaryocytic differentiation through the upregulation of Jak/Stat3 signaling pathway
- Stem cell regulation by Jak/Stat signaling in Drosophila
- Stem cell self-renewal specified by JAK-STAT activation in response to a support cell cue
- Steroidogenic Genes Expressions Are Repressed By High Levels Of Leptin And The Jak/Stat Signaling Pathway In Ma-10 Leydig Cells
- Stigmasterol Exhibits Potent Antitumor Effects In Human Gastric Cancer Cells Mediated Via Inhibition Of Cell Migration, Cell Cycle Arrest, Mitochondrial Mediated Apoptosis And Inhibition Of Jak/Stat Signalling Pathway
- Stimulation of invariant natural killer T cells by α‐Galactosylceramide activates the JAK‐STAT pathway in endothelial cells and reduces angiogenesis in the 5T33 …
- Stimulation Of The Jak/Stat Pathway By Lif And Osm In The Human Granulosa Cell Line Cov434
- Stopping STATs: Mechanisms of JAK-STAT Signaling Inhibition by RNA Viruses
- Strategic use of conformational bias and structure based design to identify potent JAK3 inhibitors with improved selectivity against the JAK family and the kinome
- Stress-Immune-Growth Interactions: Cortisol Modulates Suppressors Of Cytokine Signaling And Jak/Stat Pathway In Rainbow Trout Liver
- Stroma Cells Promote A S100A8/A9High-Subset Of Aml Blasts With Distinct Metabolic Features In A Jak/Stat3-Dependent Manner
- Stromal Lkb1 Deficiency Leads To Gastrointestinal Tumorigenesis Involving The Il-11–Jak/Stat3 Pathway
- Structural And Functional Characterization Of The Jh2 Pseudokinase Domain Of JAK Family Tyrosine Kinase 2 (Tyk2)
- Structural Bases of Receptor-JAK-STAT Interactions
- Structure And Functional Characterization Of The Conserved JAK Interaction Region In The Intrinsically Disordered N-Terminus Of Socs5
- Structure of a pseudokinase-domain switch that controls oncogenic activation of JAK kinases
- Structure of the pseudokinase–kinase domains from protein kinase TYK2 reveals a mechanism for Janus kinase (JAK) autoinhibition
- Study on correlation of Jak/Stat signal pathway with progression and prognosis in hepatocellular carcinoma
- Study On Expression Of Il-6/Jak/Stat3 Signaling Pathway In Category Iiib Prostatitis
- Study On The Role Of Jak/Stat Signaling Pathway During Chicken Spermatogonial Stem Cells Generation Based On Rna-Seq
- Study On The Role Of Mir-124 In Exerting Tumor Suppressing Effects On Cervical Cancer By Regulating The JAK-Stat3 Signaling Pathway
- Stüve–Wiedemann Syndrome: Recurrent Neonatal Infections Caused By Impairment Of Jak/Stat 3 Pathway
- Substance P stimulates cyclooxygenase-2 and prostaglandin E2 expression through JAK-STAT activation in human colonic epithelial cells
- Suppl 2: JAK Kinases in Health and Disease: An Update
- Supplemental Data A Systematic Analysis of Tinman Function Reveals Eya and JAK-STAT Signaling as Essential Regulators of Muscle Development
- Supplemental oxygen can cause intravitreous neovascularization through Jak/Stat pathways in a model of retinopathy of prematurity
- Supplementary material: A simple work flow for biologically inspired model reduction–application to early JAK-STAT signaling
- Supplementary Materials: Eriobotrya Japonica Water Extract Characterization: An Inducer Of Interferon-Gamma Production Mainly By JAK-Stat Pathway
- Suppresses Epithelial–Mesenchymal Transition, Invasion, And Migration Of Papillary Thyroid Carcinoma Cells Via The Jak1‐Mediated Jak/Stat Signaling Pathway
- Suppresses Nasopharyngeal Cancer By Targeting Stem Cell-Like Population, Inducing Apoptosis, Inhibiting Emt And Dysregulating Jak/Stat Signaling Pathway
- Suppresses Uropathogenic Escherichia Coli Invasion And Colonization Within Prostate Cells And Inhibits Inflammatory Responses Through Jak/Stat-1 Signaling …
- Suppression of autoimmune arthritis by small molecule inhibitors of the Jak/Stat pathway
- Suppression Of Bmx‐Arhgap Fusion Gene Inhibits Epithelial‐Mesenchymal Transition In Gastric Cancer Cells Via Rhoa‐Mediated Blockade Of Jak/Stat Axis
- Suppression of IL-1β expression by the JAK 2 inhibitor AG490 in cerulein-stimulated pancreatic acinar cells
- Suppression of iNOS expression by fucoidan is mediated by regulation of p38 MAPK, Jak/Stat, AP-1 and IRF-1, and depends on up-regulation of scavenger receptor …
- Suppression of leptin-induced hypothalamic Jak/Stat signalling and feeding response during pregnancy in the mouse
- Suppression Of Seizure-Induced Increased Expression Of Jak/Stat Signaling In Kindling Model Of Epileptogenesis Using Isoxylitones [E/Z]
- Suppression Of Usp18 Potentiates The Anti-Hbv Activity Of Interferon Alpha In Hepg2. 2.15 Cells Via Jak/Stat Signaling
- Suppressor of cytokine signaling (SOCS)-1 suppresses a proliferation of malignant melanoma cells via the suppression of Jak/Stat and the activation of p53 …
- Suppressor Of Cytokine Signaling 3 Modulates Transforming Growth Factor-Β Signaling In Human Chondrocytes Through The Inhibition Of The Jak/Stat3 Pathway
- Suppressor Of Cytokine Signaling-1 Inhibits Melanoma Cell Growth By The Suppression Of Jak/Stat And The Activation Of P53 Signaling Pathways
- Suppressor of cytokine signaling-1 selectively inhibits LPS-induced IL-6 production by regulating JAK–STAT
- Suppressors And Activators Of JAK-Stat Signaling At Diagnosis And Relapse Of Acute Lymphoblastic Leukemia In Down Syndrome
- Suppressors Of Cytokine Signaling (SOCS) Modulate Jak/Stat-Mediated Cell Responses In CBD After Beryllium Treatment
- Suppressors of cytokine signaling (SOCS) proteins and Jak/Stat pathways: regulation of T-cell inflammation by SOCS1 and SOCS3
- Suppressors of cytokine signaling (SOCS): inhibitors of the Jak/Stat pathway
- Suppressors of cytokine signaling modulate Jak/Stat-mediated cell responses during atherosclerosis
- Surfactant Protein C Dampens Inflammation By Decreasing Jak/Stat Activation During Lung Repair
- Survival response of hippocampal neurons under low oxygen conditions induced by Hippophae rhamnoides is associated with Jak/Stat signaling
- Syndrome And Reversible Liver Function Abnormalities In Patients With Systemic Lupus Erythematosus Treated With The Highly Selective JAK-1 Inhibitor Gsk2586184
- Synergistic Activations Of Reg Iα And Reg Iβ Promoters By Il-6 And Glucocorticoids Through Jak/Stat Pathway In Human Pancreatic Β Cells
- Synergistic Anti-Tumor Effect Of Combined Inhibition Of Egfr And Jak/Stat3 Pathways In Human Ovarian Cancer
- Synthesis and evaluation of curcumin-like compounds as inhibitors of the Jak/Stat pathway in cancer
- Systematic identifiability testing for unambiguous mechanistic modeling–application to JAK-stat, map kinase, and nf-κ b signaling pathway models
- Systemic Sclerosis, Polycythemia Vera, And JAK pathway: Coincidence Or Correlation?
- Systemic Treatment Of Psoriasis With JAK Inhibitors: A Review
- Systemic Treatment With Resveratrol Alleviates Adjuvant Arthritis-Interstitial Lung Disease In Rats Via Modulation Of Jak/Stat/Rankl Signaling Pathway
- Systems biology of Jak/Stat signalling
- Systems biology of JAK-STAT signalling in human malignancies
- Systems Biology of the JAK‐STAT Signaling Pathway
- T cells JAK up integrin activity
- Tamoxifen alleviates hepatitis C virus‐induced inhibition of both toll‐like receptor 7 and JAK‐STAT signalling pathways in PBMCs of infected Egyptian females
- Tanshinone I Inhibits The Growth And Metastasis Of Osteosarcoma Via Suppressing Jak/Stat3 Signalling Pathway
- Tanshinone L Exhibits Anticancer Effects In Human Endometrial Carcinoma Hec-1-A Cells Via Mitochondrial Mediated Apoptosis, Cell Cycle Arrest And Inhibition Of Jak/Stat Signalling Pathway
- Targeted Analysis Reveals An Important Role Of JAK-Stat-Socs Genes For Milk Production Traits In Australian Dairy Cattle
- Targeted Blockade Of Jak/Stat3 Signaling Inhibits Ovarian Carcinoma Growth
- Targeted Blockade Of Jak/Stat3 Signaling Inhibits Proliferation, Migration And Collagen Production As Well As Inducing The Apoptosis Of Hepatic Stellate Cells
- Targeted Next Generation Sequencing Of Breast Implant-Associated Anaplastic Large Cell Lymphoma Reveals Mutations In Jak/Stat Signalling Pathway Genes, Tp53 …
- Targeted Sequencing Identified Jak/Stat Pathway Alteration In Kras Mutated Metastatic Colorectal Cancer.
- Targeted Sequencing Identifies Associations Between Il7R-JAK Mutations And Epigenetic Modulators In T-Cell Acute Lymphoblastic Leukemia
- Targeting Cytokine Signaling And Lymphocyte Traffic Via Small Molecules In Inflammatory Bowel Disease: JAK Inhibitors And S1Pr Agonists
- Targeting Few To Help Hundreds: Jak, Mapk And Rock Pathways As Druggable Targets In Atypical Chronic Myeloid Leukemia
- Targeting JAK Kinase In Solid Tumors: Emerging Opportunities And Challenges
- Targeting Jak/Stat Adaptive Mechanism With Jak1 Inhibitor Azd4205 Reduces Residual Disease And Prolongs Benefit Of Osimertinib
- Targeting Jak/Stat Pathway As A Therapeutic Strategy Against Sp/Cd44+ Tumorigenic Cells In Akt/Β-Catenin-Driven Hepatocellular Carcinoma
- Targeting Jak/Stat signaling pathway in inflammatory diseases
- Targeting Jak/Stat Signaling To Prevent Rejection After Kidney Transplantation: A Reappraisal
- Targeting Jak/Stat Signalling In Inflammatory Skin Diseases With Small Molecule Inhibitors
- Targeting JAK-Stat Signal Transduction In Ibd
- Targeting JAK-STAT signal transduction pathways in human carcinomas
- Targeting myeloproliferative neoplasms with JAK inhibitors
- Targeting of Jak/Stat pathway in antigen presenting cells in cancer
- Targeting Of JAK-Stat Signaling In Breast Cancer: Therapeutic Strategies To Overcome Drug Resistance
- Targeting Of JAK-Stat Signaling Pathway And Bcl-2 Family Proteins In Ph-Like Acute Lymphoblastic Leukemia
- Targeting Socs Proteins To Control JAK-Stat Signalling In Disease
- Targeting survival cascades induced by activation of Ras/Raf/MEK/ERK, PI3K/PTEN/Akt/mTOR and Jak/Stat pathways for effective leukemia therapy
- Targeting the IL-6/JAK pathway in Breast Cancer
- Targeting The Il-6/Jak/Stat3 Signalling Axis In Cancer
- Targeting the interleukin-6/Jak/Stat pathway in human malignancies
- Targeting the Jak/Stat pathway for immunosuppression
- Targeting the Jak/Stat pathway in cytotoxic T lymphocytes (CTL) by next generation sequencing (NGS)
- Targeting The Jak/Stat Pathway In T Cell Lymphoproliferative Disorders
- Targeting the Jak/Stat pathway in the treatment of Parkinson’s disease (THER6P. 847)
- Targeting the Jak/Stat signaling pathway is highly effective in xenograft models of early T cell precursor (ETP) acute lymphoblastic leukemia (ALL)
- Targeting the JAK-STAT pathway in lymphoma: a focus on pacritinib
- Targeting The JAK-Stat Pathway In The Treatment Of ‘Th2-High’Severe Asthma
- Targeting the tumor microenvironment: JAK-STAT3 signaling
- Tc-Ptp And Ptp1B: Regulating Jak–Stat Signaling, Controlling Lymphoid Malignancies
- Temporal activation of the JAK-STAT pathway in relation to cardiac gene expression in a mouse model of cardiac dysfunction.
- Termination and modulation of interleukin-6-type cytokine signalling through the gp130/Jak/Stat pathway
- Teroristické Útoky 9/11-JAK Se Změnil Svět
- Tert Rs2736100 A>C Snp And Jak2 46/1 Haplotype Significantly Contribute To The Occurrence Of Jak2 V617F And Calr Mutated Myeloproliferative Neoplasms – A …
- Tetramethylpyrazine Attenuates Blood-Brain Barrier Disruption In Ischemia/Reperfusion Injury Through The Jak/Stat Signaling Pathway
- TEUGHELS, A., DE ROECK, G. and SUYKENS, JAK, Updating of finite element models using coupled local minimisers (CLM), Proceedings of 3rd Int. Conf. on …
- TGF-β drives tumor-progression via Jak/Stat3-signaling in advanced HCC.
- Tgfβ1 Is Essential For Mscs-Cafs Differentiation And Promotes Hct116 Cells Migration And Invasion Via Jak/Stat3 Signaling
- The Abl And JAK Tyrosine Kinase Pathways May Be Co-Activated In A Subset Of Bcr/Abl1 Positive Acute Lymphoid Leukemia
- The action of JAK, SMAD and ERK signal pathways on hepcidin suppression by polysaccharides from Angelica sinensis in rats with iron deficiency anemia
- The action of leptin in the ventral tegmental area to decrease food intake is dependent on JAK-2 signaling
- The activation of Jak/Stat signal pathway in hypereosinophilic syndrome and the patients therapeutic response to imatinib
- The activity of JAK-STAT pathways in rheumatoid arthritis: constitutive activation of STAT3 correlates with interleukin 6 levels
- The Activity Of The JAK-Stat Pathway In Infantile Haemangioma And The Haemogenic Potential Of Infantile Haemangioma Explant Derived Cells
- The antagonist of the JAK-1/STAT-1 signaling pathway improves the severity of cerulein-stimulated pancreatic injury via inhibition of NF-κB activity
- The Anti-Apoptotic Bcl-2 Family Protein A1/Bfl-1 Regulates Neutrophil Survival And Homeostasis And Is Controlled Via Pi3K And Jak/Stat Signaling
- The antihypertension drug doxazosin suppresses Jak/Stats phosphorylation and enhances the effects of IFN-α/γ-induced apoptosis
- The Antitumor And Immunomodulatory Effect Of Yanghe Decoction In Breast Cancer Is Related To The Modulation Of The Jak/Stat Signaling Pathway
- The Apoptosis Of Fibroblast-Like Synoviocytes Derived From Rats With Collagen-Induced Arthritis By Suppressing The Activation Of The Jak/Stat Signaling Pathway
- The arrival of JAK inhibitors: advancing the treatment of immune and hematologic disorders
- The Bcr-Abl1-Negative Myeloproliferative Neoplasms: A Review Of JAK Inhibitors In The Therapeutic Armamentarium
- The BET Bromodomain inhibitor OTX015 targets the NFKB, TLR and Jak/Stat pathways and shows pre-clinical activity as single agent and in combination in mature …
- The Chemopreventive Phytochemical Moringin Isolated From Moringa Oleifera Seeds Inhibits Jak/Stat Signaling
- The Complex of CNTF-CNTFRα Upregulates Connexin43 and Intercellular Coupling in Astrocytes Via the Jak/Stat Pathway Running Title: CNTF Complex Increases …
- The Complex States Of Astrocyte Reactivity: How Are They Controlled By The Jak–Stat3 Pathway?
- The Correlation Between The Soluble Triggering Receptor Expressed On Myeloid Cells-1 And The Janus Kinase/Signal Transducer And Activator Of Transcription (Jak/Stat) Pathway In Rats With Abdominal Sepsis
- The data-based mathematical modeling and parameter identification in JAK-STAT signaling pathway by using a hybrid evolutionary algorithm
- The difference of gene expression profile of Jak/Stat signaling pathway in 5-fluorouracil resistant cell line of human gastric adenocarcinoma
- The differential role of Jak/Stat signaling in retinal degeneration
- The differential role of JAK-2/STAT-1 in the r egulation of lipopolysaccharide-induced inducible nitric oxide synthase and cyclooxygenase-2 productions by CKD712
- The Differential Role of JAK-STAT Signaling in Retinal Degeneration
- The Drosophila homolog of the human tumor suppressor gene BHD interacts with the JAK-STAT and Dpp signaling pathways in regulating male germline …
- The Drosophila JAK-STAT pathway in blood cell formation and immunity
- The Dynamic Changes Of Interferon Lambdas Related Genes And Proteins In Jak/Stat Pathway In Both Acute And Chronic Hiv-1 Infected Patients
- The Effect Of Akt-1 And JAK-1 Silencing On The Angiogenesis, Proliferation And Apoptosis In Oral Squamous Cell Carcinoma; In Vitro And In Vivo
- The Effect Of Fennel (Foeniculum Vulgare) On The Jak/Stat Pathway And Intestinal Barrier Function
- The Effect Of Glucagon-Like-Peptide-1 And Vitamin D On JAK-Stat Pathway In Dbdb Mice And In Endotelial Cells Exposed To A Diabetic …
- The Effect of Jak/Stat Pathway in Pathogenesis of Diabetic Nephropathy
- The Effect Of Leptin And Resveratrol On Jak/Stat Pathways And Sirt-1 Gene Expression In The Renal Tissue Of Ischemia/Reperfusion Induced Rats.
- The effect of matrine and oxymatrine on proliferation and apoptosis and signaling transduction of JAK-STAT in SMMC-7721 cell line [J]
- The Effect of Orf Virus Infection on the IFN Stimulated Jak/Stat Signalling Pathway
- The Effect Of Pre-Transplant JAK 1/2 Inhibitors On Outcomes Of Myelofibrosis Patients Who Receive Allogeneic Stem Cell Transplant.
- The effect of the Jak/Stat signal pathway on apoptosis-related gene in the synovial tissue of rat rheumatoid arthritis
- The Effects Of JAK Inhibitors In A Mouse Model Of Hiv Neurocognitive Disorders (S41. 008)
- The Efficacy Of Pregabalin And Prevents Its Motor Impairment In Paclitaxel-Induced Neuropathy In Rats: Role Of Notch1 Receptor And Jak/Stat Signaling Pathway
- The Egfr Pathway Is Involved In The Regulation Of Pd-L1 Expression Via The Il-6/Jak/Stat3 Signaling Pathway In Egfr-Mutated Non-Small Cell Lung Cancer
- The Emerging Safety Profile Of JAK Inhibitors In Rheumatic Disease
- The empirical study of the effect of blocking the JAK-STAT signal pathway in the treatment of rat’s rheumatoid arthritis
- The endocytic control of Jak/Stat signalling in Drosophila
- The entomopathogenic fungus Beauveria bassiana activate toll and JAK-STAT pathway-controlled effector genes and anti-dengue activity in Aedes aegypti
- The essential role of the Jak/Stat1 signaling pathway in the expression of INOS in intestinal epithelial cells and its regulation by butyrate
- The excavation of Non Ban Jak, Northeast Thailand-a report on the first three seasons
- The Expression Level And Value Of Mir-21, Mir-19A And Jak/Stat Pathway In Peripheral Monocytes Of Juvenile Idiopathic Arthritis
- The Expression Of Pd-L1 On Human And Murine Pancreatic Ductal Adenocarcinoma Is Enhanced By Anticancer Agents Via The Jak/Stat Pathway
- The expression of several molecules in Jak/Stats signaling pathway in MHCC97 hepatocellular carcinoma cells with high metastatic potential
- The fertile field of Drosophila Jak/Stat signalling
- The frequency of JAK2 V617F mutation, expression level of phosphorylated Jak/Stats proteins and their clinical significance in myeloproliferative disorders patients
- The Fruiting Bodies Of Lepista Sordida As Potent Inhibitors Of Indoleamine 2, 3-Dioxygenase (Ido) In Hepg2 Cells Via Blocking Of Stat1-Mediated JAK-Pkc-Δ Signaling …
- The function of JAK-STATs pathway in proliferation and differentiation of human hypertrophic scar fibroblast induced by connective tissue growth factor [J]
- The functional role of the JAK–STAT pathway in post-infarction remodeling
- The fusion protein PAX5-JAK2 constitutively activates JAK-STAT signaling
- The granulocyte colony stimulating factor (G‐CSF) activates Jak/Stat and MAPK pathways in a trophoblastic cell line
- The Hopscotch JAK kinase requires the Raf pathway to promote blood cell activation and differentiation in Drosophila
- The IL-6/Jak/Stat3 feed-forward loop drives tumorigenesis and metastasis
- The IL-6/Jak/Stat3 feed-forward loop drives tumorigenesis and metastasis.
- The IL-6/Jak/Stat3 pathway: potential therapeutic strategies in treating colorectal cancer
- The Immediate Early Protein Wsv187 Can Influence Viral Replication Via Regulation Of Jak/Stat Pathway In Drosophila
- The Impact Of Jak/Stat Inhibitor Ruxolitinib On The Genesis Of Lymphoproliferative Diseases
- The impact of JAK-STAT signaling on muscle regeneration
- The Impact Of Mean Platelet Volume (Mpv) And JAK-2 Mutation On Thrombosis In Chronic Myeloproliferative Diseases
- The Impact Of Meisoindigo On Apoptosis And Proliferation Of Set2 Cell Line By JAK-Stat Pathway
- The impact of microRNAs on signaling pathways: From general perspectives to a computational model of the JAK-STAT pathway
- The Impact Of Pre-Transplant JAK 1/2 Inhibitors On Myelofibrosis Outcomes
- The Inflammatory Cytokine Interferon‐Gamma Inhibits Sortilin‐1 Expression In Hepatocytes Via The Jak/Stat Pathway
- The influence of benazepril blocking RAS on JAK-STAT signal transduction pathway of SHR’s myocardium
- The influence of HBV and its antigens on the expressions of JAK-STAT signal transduction pathway molecules and antiviral proteins of IFN alpha
- The influence of HBV on the expression of interferon-α JAK-STAT signal transductive pathway molecules and MxA mRNA in HepG2. 2.15 cells
- The Inr/Akt/Torc1 Growth-Promoting Signaling Negatively Regulates Jak/Stat Activity And Migratory Cell Fate During Morphogenesis
- The Interactions Between Jak/Stat Signaling Ligands in Drosophila Melanogaster
- The involvement of Galectins in the modulation of the Jak/Stat pathway in myeloproliferative neoplasia
- The involvement of JAK-STAT3 in cell motility, invasion, and metastasis
- The involvement of the JAK-STAT signaling pathway in chronic inflammatory skin disease atopic dermatitis
- The JAK 2/Stat 3 Pathway Is Involved In The Anti‐Melanoma Effects Of Atractylenolide I
- The JAK and STAT family members of the mandarin fish Siniperca chuatsi: molecular cloning, tissues distribution and immunobiological activity
- The JAK Inhibitors: Do They Bring A Paradigm Shift For The Management Of Rheumatic Diseases?
- The JAK inihibitor Tofacitinib sup-presses synovial JAK-stat signalling in rheumatoid arthritis
- The JAK kinases: not just another kinase drug discovery target
- The Jak/Stat 3 Signalling Pathway Regulated Angiogenesis In An Endothelial Cell/Adipose‐Derived Stromal Cell Co‐Culture, 3D Gel Model
- The Jak/Stat pathway
- The Jak/Stat pathway and Drosophila development
- The Jak/Stat pathway but not the Erk1/2 pathway mediates IL-6/sIL-6R downregulation of type II collagen, aggrecan core and link protein transcription in articular …
- The Jak/Stat pathway in Drosophila hematopoiesis: function and regulatory mechanisms
- The Jak/Stat pathway in model organisms: emerging roles in cell movement
- The Jak/Stat Pathway In Obesity And Diabetes
- The Jak/Stat pathway in rheumatoid arthritis: pathogenic or protective?
- The Jak/Stat Pathway In Skeletal Muscle Pathophysiology
- THE Jak/Stat PATHWAY IN THE INTESTINE AFTER THERMAL INJURY OR INFLAMMATION: 162
- The Jak/Stat Pathway Is Activated In Systemic Sclerosis And Is Effectively Targeted By Tofacitinib
- The Jak/Stat pathway is essential for opioid-induced cardioprotection: JAK2 as a mediator of STAT3, Akt, and GSK-3β
- The Jak/Stat pathway is involved in synaptic plasticity
- The Jak/Stat Pathway Is Involved In The Upregulation Of Pd-L1 Expression In Pancreatic Cancer Cell Lines
- The Jak/Stat pathway is not sufficient to sustain the antiproliferative response in an interferon-resistant human melanoma cell line
- The Jak/Stat pathway is required for border cell migration during Drosophila oogenesis
- THE Jak/Stat PATHWAY IS REUTILIZED IN DROSOPHILA SPERMATOGENESIS
- The Jak/Stat pathway positively regulates DPP signaling in the Drosophila germline stem cell niche
- The Jak/Stat pathway regulates proximo‐distal patterning in Drosophila
- The Jak/Stat pathway: a novel way to regulate PI3K activity
- The Jak/Stat protein activation–role in cancer development and targeted therapy
- The Jak/Stat Signaling Cascade In Gastric Carcinoma
- The Jak/Stat Signaling Cascades Of Multiple Cytokines Are Dysregulated During West Nile Virus Infection.
- The Jak/Stat signaling pathway
- The Jak/Stat Signaling Pathway And Photobiomodulation In Chronic Wound Healing
- The Jak/Stat signaling pathway in leukemogenesis
- The Jak/Stat signaling pathway is downregulated at febrile temperatures
- The Jak/Stat signaling pathway is required for the initial choice of sexual identity in Drosophila melanogaster
- The Jak/Stat signaling pathway mediates β-amyloid protein-induced TNF-α action of microglia in vitro [J]
- The Jak/Stat3 Axis: A Comprehensive Drug Target For Solid Malignancies
- The Jak/Stat3 Pathway Is A Common Inducer Of Astrocyte Reactivity In Alzheimer’S And Huntington’S Diseases
- The Jak/Stat3 Signaling Pathway In Vaccinia Virus Infection
- The Jak/Stat3 Signaling Pathway Mediates Inhibition Of Host Cell Apoptosis By Chlamydia Psittaci Infection
- The Jak1 SH2 domain does not fulfill a classical SH2 function in Jak/Stat signaling but plays a structural role for receptor interaction and up-regulation of receptor …
- The JAK-STAT and ERK signalling pathways and their implication in seasonal body weight regulation of the Siberian hamster, Phodopus sungorus
- The JAK-STAT pathway
- The JAK-STAT pathway and hematopoietic stem cells from the JAK2 V617F perspective
- The JAK-STAT pathway at twenty
- The JAK-STAT pathway controls Plasmodium vivax load in early stages of Anopheles aquasalis infection
- The JAK-STAT pathway in hypertrophic stress signaling and genomic stress response
- The JAK-STAT pathway in rheumatoid arthritis.
- The JAK-STAT pathway is critical in ventilator-induced diaphragm dysfunction
- The JAK-Stat Pathway Is Regulated By Mirna Mediated Ribosomal Frameshifting
- The JAK-STAT Pathway is Required for Multiple Early Events in Drosophila Oogenesis
- The JAK-Stat Pathway of Cytokine Signaling
- The JAK-STAT pathway regulation of endothelial cell migration and differentiation
- The JAK-STAT pathway stimulated by interferon α or interferon β
- The JAK-STAT pathway stimulated by interferon γ
- The JAK-STAT pathway stimulated by interleukin 6
- The JAK-STAT pathway: a therapeutic target in hematological malignancies
- The JAK-Stat Pathway: Impact On Human Disease And Therapeutic Intervention
- The JAK-stat signal transduction pathway in melanoma
- The JAK-STAT signaling network in the human B-cell: an extreme signaling pathway analysis
- The JAK-Stat Signaling Pathway Is Differentially Activated In Calr-Positive Compared With Jak2V617F-Positive Et Patients
- The JAK-STAT signaling pathway is required but not sufficient for the antiviral response of drosophila
- The JAK-STAT signaling pathway of interferons system: snapshots
- The JAK-STAT signaling pathway: input and output integration
- The JAK-STAT target Chinmo prevents sex transformation of adult stem cells in the Drosophila testis niche
- The JAK-STAT transcriptional regulator, STAT-5, activates the ATM DNA damage pathway to induce HPV 31 genome amplification upon epithelial …
- The JAK-Stat1 Transcriptional Signature In Peripheral Immune Cells Reveals Alterations Related To Illness Duration And Acuity In Psychosis
- The Janus Kinase (Jak) Ferm And Sh2 Domains: Bringing Specificity To Jak–Receptor Interactions
- The Long Noncoding Rna Meg3 And Its Target Mir-147 Regulate Jak/Stat Pathway In Advanced Chronic Myeloid Leukemia
- The maternal Jak/Stat pathway of Drosophila regulates embryonic dorsal-ventral patterning
- The Molecular Details Of Cytokine Signaling Via The Jak/Stat Pathway
- The molecular regulation of Janus kinase (JAK) activation
- The myocardial Jak/Stat pathway: from protection to failure
- The Nano-Tio2 Exposure Can Induce Hepatic Inflammation Involving In A Jak–Stat Signalling Pathway
- The negative regulation of Jak/Stat signaling
- The Neuroprotective Effects of Rattin Against Neurotoxic Aβ are Involved in Jak/Stat3 and Calcium Homeostasis
- The neutralization of type I IFN biologic actions by anti-IFNAR-2 monoclonal antibodies is not entirely due to inhibition of JAK-Stat tyrosine phosphorylation
- The New Entries In The Therapeutic Armamentarium: The Small Molecule JAK Inhibitors
- The NS5 protein of the virulent West Nile virus NY99 strain is a potent antagonist of type I interferon-mediated JAK-STAT signaling
- The Participation Of Fibroblast Growth Factor 23 (Fgf23) In The Progression Of Osteoporosis Via Jak/Stat Pathway
- The Polyhomeotic protein induces hyperplastic tissue overgrowth through the activation of the Jak/Stat pathway
- The position and function of the Notch‐mediated eye growth organizer: the roles of Jak/Stat and four‐jointed
- The Possible Role of Jak/Stat Signal in Neuronal Cell Death
- The possible role of the Jak/Stat pathway in lymphocytes at the fetomaternal interface
- The Potential Effect Of Methylseleninic Acid (Msa) Against Γ-Irradiation Induced Testicular Damage In Rats: Impact On Jak/Stat Pathway
- The Production of IFN- by 3LL/TNF–Activated Macrophages Requires p38. JAK-2 Signalling and is Enhanced by New Protein Synthesis.
- The raf kinase inhibitor sorafenib inhibits JAK-STAT signal transduction in human immune cells
- The Raf Kinase Inhibitor Sorafenib Inhibits Jak–Stat Signal Transduction In Human Immune Cells
- The Ras/Raf/MEK/extracellular signal-regulated kinase pathway induces autocrine-paracrine growth inhibition via the leukemia inhibitory factor/Jak/Stat pathway
- The Research Progress of JAK-STAT Pathways in Cardiovascular Disease
- The role of a non-canonical JAK-STAT pathway in IFN therapy of poxvirus infection and multiple sclerosis: An example of Occam’s Broom?
- The Role Of Allogeneic Stem-Cell Transplant In Myelofibrosis In The Era Of JAK Inhibitors: A Case-Based Review
- The Role Of JAK Inhibitors In Multiple Myeloma
- The Role Of JAK Inhibitors In The Treatment Of Alopecia Areata: A Systematic Review
- The role of JAK pathway dysregulation in the pathogenesis and treatment of acute myeloid leukemia
- The role of Jak/Stat pathway in the synthesis of prostaglandin E2 by macrophages infected with Francisella tularensis (56.24)
- The role of Jak/Stat pathways in osteoclast differentiation
- The role of Jak/Stat signaling in heart tissue renin-angiotensin system
- The Role Of Jak/Stat Signaling Pathway And Tnf-Α Crosstalk In Human Colorectal Cancer
- The Role Of Jak/Stat Signalling In The Pathogenesis, Prognosis And Treatment Of Solid Tumours
- The Role Of Jak/Stat3 Signaling Pathway On Apoptosis Of Lung Adenocarcinoma Cell Line Pc-9 Induced By Icotinib
- The role of JAK-3 in regulating TLR-mediated inflammatory cytokine production in innate immune cells
- The role of JAK–STAT signaling in adipose tissue function
- The Role Of JAK-Stat Signaling Pathway And Its Regulators In The Fate Of T Helper Cells
- THE ROLE OF JAK-STAT SIGNALING PATHWAY IN CHOLESTEATOMA: AN IMMUNOHISTOCHEMICAL ASSAY
- The role of JAK-STAT signaling within the CNS
- The Role Of JAK-Stat Signalling Pathway Promotes Neurogenic-To-Gliogenic Shift In The Brain Of Ts1Cje Mouse Model For Down Syndrome
- THE ROLE OF JAK–STAT3 SIGNALLING PATHWAY DURING FETAL LUNG DEVELOPMENT
- The role of Ken&Barbie in Jak/Stat signalling during development of Drosophila melanogaster
- The Role of Phosphatases and Reactive Oxygen Species in Regulation of the Jak/Stat Pathway
- The role of SH2-B family members in signaling by JAK family tyrosine kinases.
- The role of SOCS proteins in negative regulation of JAK-STAT signaling
- The Role of STAT and the Jak/Stat Pathway In Mediating the Effects of Interleukin-6 on StAR Expression
- The role of supplemental oxygen and Jak/Stat signaling in intravitreous neovascularization in a ROP rat model
- The Role Of The Interferon-Gamma-Jak/Stat Pathway In Rheumatoid Arthritis
- The role of the Jak/Stat pathway in a lipopolysaccharide-induced mouse model of acute lung injury
- The Role of the Jak/Stat Pathway in Inflammatory Bowel Diseases
- The Role Of The Jak/Stat Signal Pathway In Rheumatoid Arthritis
- The role of the Jak/Stat signal transduction pathway in the biology of the human eosinophil.
- The Role Of The Jak/Stat Signalling Pathway In Immunoregulation Of Gastrointestinal Cancers
- The role of the JAK-STAT pathway and related signal cascades in telomerase activation during the development of hematologic malignancies
- The role of the Jak‐Stat pathway in chemokine‐mediated signaling in T lymphocytes
- The Role Of The JAK-Stat Pathway In Neural Stem Cells, Neural Progenitor Cells And Reactive Astrocytes After Spinal Cord Injury
- The role of the systemic inflammatory response, the JAK STAT pathway and the MAPK pathway in the prognosis of resectable pancreatic cancer
- The roles of Jak/Stat signaling in Drosophila immune responses
- The roles of the Drosophila Jak/Stat pathway
- The roles of the Jak/Stat pathway and Fasciclin III in epithelial structures during Drosophila development
- The Shh/Gli Axis Regulates Cd 90‐Mediated Liver Cancer Stem Cell Function By Activating The Il 6/JAK 2 Pathway
- The signal transduction mediated by erythropoietin and proinflammatory cytokines in the Jak/Stat pathway in the children with cerebral palsy
- The Small Gtpase Rhou Lays Downstream Of Jak/Stat Signaling And Mediates Cell Migration In Multiple Myeloma
- The SOCS and STAT from Jak/Stat signaling pathway of kuruma shrimp Marsupenaeus japonicus: molecular cloning, characterization and expression analysis
- The Specific Roles Of Jak/Stat Signaling Pathway In Sepsis
- The Spliceosomal Component Sf3B1 Is Essential For Hematopoietic Stem Cell Formation Through The Regulation Of The Jak/Stat Signaling Pathway
- The surface expression of CD25 at different stages of proliferative response in human lymphocytes. I. The role of JAK and Src tyrosine kinases as revealed by …
- The synthetic α-bromo-2′, 3, 4, 4′-tetramethoxychalcone (α-Br-TMC) inhibits the Jak/Stat signaling pathway
- The T-Cell Leukemia-Associated Ribosomal Rpl10 R98S Mutation Enhances JAK-Stat Signaling
- The Temporal Profile Of Astrocytes And JAK-Stat Signal Pathway After Spinal Ischemia And Reperfusion Injury In Rabbits
- The Therapeutic Effect Of Artesunate On Rosacea Through The Inhibition Of The Jak/Stat Signaling Pathway
- The Tumor Seed: Chronic Inflammation In Chronic Obstructive Pulmonary Disease Induces Growth And Metastasis Of Lung Cancer Cells Via Il-6/Jak/Stat3/Nf-? B …
- The Tumor Suppressive Effects Of Hpp1 Are Mediated Through JAK-Stat-Interferon Signaling Pathways
- The ubiquitin hydrolase USP22 contributes to 3′-end processing of JAK-STAT-inducible genes
- The ubiquitin ligase TRAF6 negatively regulates the JAK-STAT signaling pathway by binding to STAT3 and mediating its ubiquitination
- The UPD3 cytokine couples environmental challenge and intestinal stem cell division through modulation of Jak/Stat signaling in the stem cell …
- The Use Of JAK Inhibitors For Low-Risk Myelofibrosis
- The Use of JAK-specific inhibitors as chemical biology tools
- The V617F JAK 2 mutation is not a frequent event in patients with cerebral venous thrombosis without overt chronic myeloproliferative disorder
- The versatile regulation of cellular events by JAK-Stat signaling: from transcriptional control to microtubule dynamics and energy metabolism
- Therapeutic efficacy of baicalin on experimental autoimmune encephalomyelitis through down-regulation of JAK-STAT and NF-κB signaling pathways (THER3P. 876)
- Therapeutic efficacy of suppressing the Jak/Stat pathway in models of neuroinflammation (P5199)
- Therapeutic efficacy of suppressing the Jak/Stat pathway in multiple models of experimental autoimmune encephalomyelitis
- Therapeutic potential of CPL-407-105–Novel potent Jak/Stat pathway inhibitor for the treatment of asthma
- Therapeutic Potential Of Jak/Stat Pathway Modulation In Mood Disorders
- Therapeutic suppression of constitutive and inducible JAK\STAT activation in head and neck squamous cell carcinoma.
- Therapeutic targeting of the Jak/Stat pathway
- Therapeutic Targeting Of The Proinflammatory Il-6-Jak/Stat Signalling Pathways Responsible For Vascular Restenosis In Type 2 Diabetes Mellitus
- Therapeutics Targeting Innate Immune/Inflammatory Responses Through The Interleukin-6/Jak/Stat Signal Transduction Pathway In Patients With Cancer
- Therapeutics: holding JAK back
- Three lysine residues in the common beta chain of the IL-5 receptor are required for JAK-dependent receptor ubiquitination, endocytosis and signaling
- Three lysine residues in the common β chain of the interleukin-5 receptor are required for Janus kinase (JAK)-dependent receptor ubiquitination, endocytosis, and …
- Three Members In Jak/Stat Signal Pathway From The Sea Cucumber Apostichopus Japonicus: Molecular Cloning, Characterization And Function Analysis
- Thrombin regulates vascular smooth muscle cell growth and heat shock proteins via the JAK-STAT pathway
- Thromboembolism With Janus Kinase (Jak) Inhibitors For Rheumatoid Arthritis: How Real Is The Risk?
- Thu0006 Proinflammatory Responses In The JAK-Stat Pathway In Synovial Fibroblasts Are Stimulus-Specific And Only …
- Thu0017 In Vitro Mechanistic Studies Demonstrate Filgotinib Activity That Has Potential Implications For Differentiation Among JAK Inhibitors
- Thu0024 Anti-Inflammatory Inhibitors Targeting JAK And Ikk Have An Anabolic Effect On Type Ii Collagen Turnover Ex Vivo
- Thu0037 Leptin Enhanced The Expression Of Autoantibodies And Inflammatory Cytokines Of B Cells Via Activating Erk1/2 And Jak/Stat3, 5 Pathways In Systemic Lupus …
- Thu0177 Treatment Patterns Among Patients With Rheumatoid Arthritis Treated With A Biologic Disease-Modifying Anti-Rheumatic Drug Or JAK Inhibitor: A Nation-Wide Study In Korea
- Thu0191 JAK-Stat Pathway Stimulation, A New Cause Of Inflammatory Arthritis
- Thu0203 Changes In C-Reactive Protein And Lipid Levels In Patients With Rheumatoid Arthritis Treated With Abt-494, A Selective JAK-1 Inhibitor
- Thu0210 Changes In Hemoglobin Levels Upon Treatment With Abt-494, A Selective JAK-1 Inhibitor, And Relation To Baseline Levels Of C-Reactive Protein
- Thu0212 Baricitinib-Associated Changes In Global Gene Expression During A 24-Week Phase 2 Clinical Sle Trial Describe A Mechanism Of Action Through Inhibition Of Jak/Stat And Ifn Responsive Gene Expression
- Tick‐borne encephalitis virus NS5 associates with membrane protein scribble and impairs interferon‐stimulated JAK‐STAT signalling
- Tipy A Rady JAK Se Učit A Procvičovat Anglickou Slovní Zásobu
- TM-233 Exerts Anti-Myeloma Activity and Overcomes Bortezomib-Resistance In Human Multiple Myeloma Cells By Targeting NF-κB and Jak/Stat Dual-Signaling …
- Tmem2 Inhibits Hepatitis B Virus Infection In Hepg2 And Hepg2. 2.15 Cells By Activating The Jak–Stat Signaling Pathway
- TNFα mediated IL-6 secretion is regulated by Jak/Stat pathway but not by MEK phosphorylation and AKT phosphorylation in U266 multiple myeloma cells
- Tnf-Α-Sensitive Brain Pericytes Activate Microglia By Releasing Il-6 Through Cooperation Between Iκb-Nfκb And JAK-Stat3 Pathways
- To Study Influence of JAK-STAT Signaling Pathway in Traumatic Deep Vein Thrombosis
- Tofacitinib Inhibits Intestinal Epithelial JAK-Stat Signaling And Prevents Barrier Dysfunction Induced By Interferon-Gamma (Ifn-Γ)
- Tofacitinib: A JAK Of All Trades
- Tools and methods for studying the Drosophila Jak/Stat pathway
- Topical JAK Inhibitors For The Treatment Of Alopecia Areata And Vitiligo
- Topical Therapy For Psoriasis: A Promising Future. Focus On JAK And Phosphodiesterase-4 Inhibitors
- Toward Understanding The Touch-Screen Generation: How To Teach Them? K Porozumění „Dotykové “Generaci–JAK Je Učit?
- Towards better design and management of tsunami evacuation routes: a case study of Ao JAK Beach Road
- Traf2 And Traf5 Associated With The Signal Transducing Receptor Gp130 Limit Il-6-Driven Transphosphorylation Of Jak1 Through The Inhibition Of Proximal Jak–JAK …
- Transcription (Jak/Stat) Signaling Pathway
- Transcriptional activation of angiotensinogen gene mediated by JAK--STAT pathway in vascular smooth muscle cells
- Transcriptional analysis of Jak/Stat signaling in glioblastoma multiforme
- Transcriptional Control of Adrenal Steroidogenesis NOVEL CONNECTION BETWEEN JANUS KINASE (JAK) 2 PROTEIN AND PROTEIN KINASE A (PKA) THROUGH …
- Transcriptional Properties of the BMP, TGF-B, RTK, Wnt, Hh, Notch, and Jak/Stat Signaling Molecules in Mouse Embryonic Stem Cells
- Transcriptional regulation by STAT1 and STAT2 in the interferon JAK-STAT pathway
- Transcriptional regulation of pattern recognition receptors by Jak/Stat signaling, and the implications for disease pathogenesis
- Transcriptional targets of Drosophila Jak/Stat pathway signalling as effectors of haematopoietic tumour formation
- Transcriptional Upregulation Of Camkiiδ Through The Jak/Stat3 Pathway Is Necessary For The Il-6-Dependent Increase In Endothelial Cell Migration
- Transcriptional, Epigenetic And Pharmacological Control Of Jak/Stat Pathway In Nk Cells
- Transcriptome analysis reveals a major impact of JAK protein tyrosine kinase 2 (Tyk2) on the expression of interferon-responsive and metabolic genes
- Transcriptomic Analysis Of The Bdnf-Induced Jak/Stat Pathway In Neurons: A Window Into Epilepsy-Associated Gene Expression
- Transcriptomic Analysis Revealing Hepcidin Expression In Oryzias Melastigma Regulated Through The JAK-Stat Signaling Pathway Upon Exposure To Bap
- Transcriptomic Profiling Reveals A Potential Role For Jak/Stat Inhibition In Cdk4/6 Inhibitor-Resistant, Er+ Breast Cancers
- Transcriptomics data integration reveals JAK-STAT as a common pathway affected by pathogenic intracellular bacteria in natural reservoir hosts
- Transduction of leptin growth signals in placental cells is independent of JAK-STAT activation
- Transforming Growth Factor Β1 Promotes Migration And Invasion In Hepg2 Cells: Epithelial‑To‑Mesenchymal Transition Via Jak/Stat3 Signaling
- Translational And Clinical Advances In Jak‐Stat Biology: The Present And Future Of Jakinibs
- Translational Positioning Of Janus Kinase (Jak) Inhibitors In Alopecia Areata
- Treating A Dysregulated Jak/Stat Pathway In Cancer Cells
- Treating The Changing Face Of Western Medicine: Pharmacological Interventions On The Jak/Stat Pathway In Diabetic Complications And Its Relationship To Ageing
- Treatment and management of myelofibrosis in the era of JAK inhibitors
- JAK-Inhibitors-A-Systematic-Review-3.pdf”>Treatment Of Atopic Dermatitis Using JAK Inhibitors: A Systematic Review
- Treatment Of Hypereosinophilic Syndrome With Cutaneous Involvement With The JAK Inhibitors Tofacitinib And Ruxolitinib
- Treatment Of Interstitial Lung Disease In Stat3 Gain-Of-Function Using JAK Inhibitors
- Treatment Of Rats With The JAK-2 Inhibitor Fedratinib Does Not Lead To Experimental Wernicke’S Encephalopathy
- Treatment With Cucurbitacin B Alone And In Combination With Gefitinib Induces Cell Cycle Inhibition And Apoptosis Via Egfr And Jak/Stat Pathway In Human Colorectal …
- Treatment With JAK Inhibitors In Myelofibrosis Patients Nullifies The Prognostic Impact Of Unfavorable Cytogenetics
- Treatment With The Antipsychotic Risperidone Is Associated With Increased M1-Like JAK-Stat1 Signature Gene Expression In Pbmcs From Participants With Psychosis …
- Tripchlorolide Ameliorates Experimental Autoimmune Encephalomyelitis By Down‐Regulating Erk1/2‐Nf‐Κb And Jak/Stat Signaling Pathways
- Triptolide downregulates Rac1 and the Jak/Stat3 pathway and inhibits colitis
- Triptolide downregulates Rac1 and the Jak/Stat3 pathway and inhibits colitis-related colon cancer progression
- Triptolide inhibits IFN‐γ signaling via the Jak/Stat pathway in HaCaT keratinocytes
- Trypanosoma cruzi parasites fight for control of the JAK-STAT pathway by disarming their host
- Tumor Suppressive Role Of Bmi-1 Through Inhibition Of JAK-Stat Signaling In Leukemia
- Tumor-Derived Gm-Csf Promotes Jak/Stat3-Dependent Expression Of Ido And Pd-L1 In Myeloid Suppressor Cells (Tum6P. 954)
- Tumor-induced thymic atrophy: Alteration in interferons and Jak/Stats signaling pathways
- Tumor-induced thymic involution via inhibition of IL-7Rα and its JAK-STAT signaling pathway: Protection by black tea
- Tumour‐secreted miR‐9 promotes endothelial cell migration and angiogenesis by activating the JAK‐STAT pathway
- ‘Tuning’of type I interferon–induced JAK-STAT1 signaling by calcium-dependent kinases in macrophages
- TWEAK signals through JAK–STAT to induce tumor cell apoptosis
- Tweak/Fn14 Mediates Atrial‐Derived Hl‐1 Myocytes Hypertrophy Via JAK 2/Stat 3 Signalling Pathway
- Two Drosophila suppressors of cytokine signaling (SOCS) differentially regulate JAK and EGFR pathway activities
- Type Ii Cgmp‑Dependent Protein Kinase Inhibits Egf‑Induced Jak/Stat Signaling In Gastric Cancer Cells
- Type III interferon (IFN) induces a type I IFN-like response in a restricted subset of cells through signaling pathways involving both the JAK-STAT pathway and the …
- Type Iii Interferon Induces Distinct Socs1 Expression Pattern That Contributes To Delayed But Prolonged Activation Of Jak/Stat Signaling Pathway: Implications …
- Ubiquitin-mediated regulation of JAK-STAT signaling in embryonic stem cells
- Ubiquitous activation of Ras and Jak/Stat pathways in human HCC
- Ulinastatin Protects Rats From Sepsis‐Induced Acute Lung Injury By Suppressing The Jak‐Stat3 Pathway
- Unique Type I Interferon, Expansion/Survival Cytokines, And Jak/Stat Gene Signatures Of Multifunctional Herpes Simplex Virus-Specific Effector Memory Cd8+ Tem …
- Unmet Needs In The Treatment Of Ra In The Era Of JAK-I: Idra (Italian Delphi Rheumatoid Arthritis) Consensus
- Unplugging Jak/Stat In Chronic Myelomonocytic Leukemia
- Upd/Jak/Stat signaling represses wg transcription to allow initiation of morphogenetic furrow in Drosophila eye development
- Upregulated Microrna‐31 Inhibits Oxidative Stress‐Induced Neuronal Injury Through The Jak/Stat3 Pathway By Binding To Pkd1 In Mice With Ischemic Stroke
- Up-regulation of CC chemokine ligand 20 expression in human airway epithelium by IL-17 through a JAK-independent but MEK/NF-κB-dependent signaling pathway
- Upregulation of Fibronectin by Peroxynitrite in Mesangial Cell via the Jak/Stat Signaling Pathways
- Upregulation Of Il-9 And JAK-Stat Signaling Pathway In Children With Autism
- Up-Regulation Of Linc00346 Inhibits Proliferation Of Non-Small Cell Lung Cancer Cells Through Mediating JAK-Stat3 Signaling Pathway
- Upregulation Of Long Noncoding Rna Snhg20 Promotes Cell Growth And Metastasis In Esophageal Squamous Cell Carcinoma Via Modulating Atm‐Jak‐Pd‐L1 Pathway
- Upregulation Of Microrna‐133A And Downregulation Of Connective Tissue Growth Factor Suppress Cell Proliferation, Migration, And Invasion In Human Glioma Through The Jak/Stat Signaling Pathway
- Up-Regulation Of Mir-124 Inhibits Invasion And Proliferation Of Prostate Cancer Cells Through Mediating JAK-Stat3 Signaling Pathway
- Upregulation Of Pd-L1 Expression By Cisplatin In Esophageal Squamous Cell Carcinoma Cells Is Independent Of Interferon/Jak/Stat Pathway
- Upregulation of penile brain-derived neurotrophic factor (BDNF) and activation of the Jak/Stat signalling pathway in the major pelvic ganglion of the rat after …
- Upregulation of the Drosophila Friend of GATA gene U-shaped by Jak/Stat signaling maintains lymph gland prohemocyte potency
- Up-regulation of the Jak/Stat1 signal pathway during Chlamydia trachomatis infection
- Use Of A Dual Luciferase Cell-Based Drug Screening Assay To Study Vp24 Inhibition Of Jak/Stat Pathway And Its Reversion By Compounds
- Use of JAK inhibitors in the management of myelofibrosis: a revision of the B ritish C ommittee for S tandards in H aematology G uidelines for I nvestigation and M …
- Use of Synthetic Antibodies Targeted to the Jak/Stat Pathway in Breast Cancer
- UV-induced Ceramide Accumulation Mediates MMP-9 Expression through Jak/Stat Pathway
- V617F JAK-2 mutation in patients with essential thrombocythemia: relation to platelet, granulocyte, and plasma hemostatic and inflammatory molecules
- Vanadate enhances leptin-induced activation of Jak/Stat pathway in CHO cells
- Vanadate facilitates interferon α-mediated apoptosis that is dependent on the Jak/Stat pathway
- Varicella zoster virus can reactivate and infect cerebral adventital fibroblasts, suppressing Jak/Stat and causing stroke.(168.35)
- Ventocoris martini (Horv.) is a synonym of V. modestus (Jak.)(Heteroptera, Pentatomidae)
- Versican G1 Domain Enhances Adenoviral-Mediated Transgene Expression And Can Be Modulated By Inhibitors Of The Janus Kinase (Jak)/Stat And Src Family Kinase …
- Viral Inhibition Of The Ifn-Induced Jak/Stat Signalling Pathway: Development Of Live Attenuated Vaccines By Mutation Of Viral-Encoded Ifn-Antagonists
- Viral Inhibitors Of Ifn-?-Jak–Stat Signal Transduction And Induction Of Mhc Class Ii Gene Expression: A Brief Review
- Vitamin C enhances Nanog expression via activation of the Jak/Stat signaling pathway
- Vitamin D receptor and Jak–STAT signaling crosstalk results in calcitriol-mediated increase of hepatocellular response to IFN-α
- vitro is dependent on Jak/Stat3 signalling and that these processes can be inhibited by the expression of SOCS3 or dnSTAT3. Do these constructs have any
- War and Anti-War: Making Sense of Today’s Global Chaos (Válka a antiválka. JAK porozumět dnešnímu globálnímu chaosu)
- What would a strategic EIA of the Temelin nuclear power plant probably look like; JAK by asi vypadala strategicka EIA jaderne elektrarny Temelin
- Which Patients Are Candidatesfor JAK Inhibitors And How To Manage Patients On Jakinhibitor Treatment
- Why should we care about fly tumors? The case of JAK-STAT and EGFR cooperation in oncogenesis
- Windpipe Controls Drosophila Intestinal Homeostasis By Regulating Jak/Stat Pathway Via Promoting Receptor Endocytosis And Lysosomal Degradation
- Withaferin A inhibits Jak/Stat3 signaling and induces apoptosis of human renal carcinoma Caki cells
- Withasteroid B From D. Metel L. Regulates Immune Responses By Modulating The Jak/Stat Pathway And The Il‐17+Rorγt+/Il‐10+Foxp3+ Ratio
- WITHDRAWN: Involvement of Jak/Stat, PI3K, PKC and MAP kinases in the growth hormone induced production of cytokines in murine peritoneal macrophages in …
- WP-1034, a novel JAK-STAT inhibitor, with proapoptotic and antileukemic activity in acute myeloid leukemia (AML)
- Wp1066, A Small Molecule Inhibitor Of The Jak/Stat3 Pathway, Inhibits Ceramide Glucosyltransferase Activity
- Wsv181 Inhibits Jak/Stat Signaling And Promotes Viral Replication In Drosophila
- Xanthatin Inhibits Stat3 And Nf‐Κb Signalling By Covalently Binding To JAK And Ikk Kinases
- Xanthohumol Protects Against Renal Ischaemia Reperfusion (I/R) Injury By Scavenging Ros And Inhibition Of JAK-2/Stat-3 Inflammatory Pathway
- Xanthotoxin Suppresses Lps-Induced Expression Of Inos, Cox-2, Tnf-Α, And Il-6 Via Ap-1, Nf-Κb, And JAK-Stat Inactivation In Raw 264.7 Macrophages
- Yap1 And Taz Control Pancreatic Cancer Initiation In Mice By Direct Up-Regulation Of Jak–Stat3 Signaling
- Zap-70 positive chronic lymphocytic leukemia co-existing with JAK 2 V671F positive essential thrombocythemia: A common defective stem cell?
- Zelnorm, An Agonist Of 5-Hydroxytryptamine 4-Receptor, Acts As A Potential Antitumor Drug By Targeting Jak/Stat3 Signaling
- Zerumbone, a phytochemical from asian ginger inhibits Jak/Stat pathway, growth, apoptosis and increase taxol sensitivity of hormone refractory prostate cancer cells
- Zinc regulates the acute phase response and serum amyloid A production in response to sepsis through JAK-STAT3 signaling
- Α-Lipoic Acid Inhibits Expression Of Il-8 By Suppressing Activation Of Mapk, Jak/Stat, And Nf-Κb In H. Pylori-Infected Gastric Epithelial Ags Cells
- β‐Escin sodium inhibits inducible nitric oxide synthase expression via downregulation of the Jak/Stat pathway in A549 cells
- β-Estradiol-dependent activation of the Jak/Stat pathway requires p/CIP and CARM1