MATRIX METALLOPROTEINASES (MMPS)
January 16, 2020Gossypol
January 17, 2020
- Exercise prevents diet-induced cellular senescence in adipose tissue
- Physiological aging: links among adipose tissue dysfunction, diabetes, and frailty
- Unbiased analysis of senescence associated secretory phenotype (SASP) to identify common components following different genotoxic stresses
- Aging and adipose tissue: potential interventions for diabetes and regenerative medicine
- Roles of chemokine ligand-2 (CXCL2) and neutrophils in influencing endothelial cell function and inflammation of human adipose tissue
- Ablation of XP-V gene causes adipose tissue senescence and metabolic abnormalities
- The emerging role of senescent cells in tissue homeostasis and pathophysiology
- Cellular senescence and the senescent secretory phenotype in age-related chronic diseases
- JAK inhibition alleviates the cellular senescence-associated secretory phenotype and frailty in old age
- Growth hormone action predicts age-related white adipose tissue dysfunction and senescent cell burden in mice
- Aging-related inflammation in osteoarthritis
- Cellular senescence in type 2 diabetes: a therapeutic opportunity
- The fat cell senescence hypothesis: a mechanism responsible for abrogating the resolution of inflammation in chronic disease
- Feast and famine: adipose tissue adaptations for healthy aging
- Macrophages in age-related chronic inflammatory diseases
- Proposed metabolic vicious circle in patients with large myocardial infarcts and high plasma-free-fatty-acid concentrations
- Perspective: targeting the JAK/STAT pathway to fight age-related dysfunction
- Effect of low-dose rapamycin on senescence markers and physical functioning in older adults with coronary artery disease: results of a pilot study.
- Systemic DNA damage response and metabolic syndrome as a premalignant state
- Stem cell senescence and regenerative paradigms
- Cellular senescence in ageing, age-related disease and longevity
- Contribution of adipose tissue inflammation to the development of type 2 diabetes mellitus
- Phytochemicals suppress nuclear factor-κB signaling: impact on health span and the aging process
- Effect of lipopolysaccharides on adipogenic potential and premature senescence of adipocyte progenitors
- Developments in our understanding of the effects of growth hormone on white adipose tissue from mice: implications to the clinic
- Cellular senescence in aging and age-related disease: from mechanisms to therapy
- Deleted in B reast C ancer 1 regulates cellular senescence during obesity
- Growth differentiation factor 6 derived from mesenchymal stem/stromal cells reduces age-related functional deterioration in multiple tissues
- Mitochondrial dysfunction induces senescence with a distinct secretory phenotype
- Impact of growth hormone on regulation of adipose tissue
- Senescence-associated secretory phenotype (SASP) involvement in the development of cancer, aging, and age related diseases
- Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders
- Curcumin, inflammation, ageing and age-related diseases
- Inflammation, ageing and chronic disease
- Geroscience: linking aging to chronic disease
- Osteoarthritis as an inflammatory disease (osteoarthritis is not osteoarthrosis!)
- Mitochondrial dysfunction meets senescence
- Finding Shangri-La: limiting the impact of senescence on aging
- Inflamm-ageing
- Characterization of senescence of culture-expanded human adipose-derived mesenchymal stem cells
- An experiment to determine the active therapeutic moiety of sulphasalazine
- Aging of the human innate immune system in HIV infection
- Metabolic syndrome is a real disease and premalignant state induced by oncogenic stresses to block malignant transformation
- Mechanisms and metabolic implications of regional differences among fat depots
- The role of inflammation in age-related disease
- “Inflammaging” as a druggable target: a senescence-associated secretory phenotype—centered view of type 2 diabetes
- Antagonizing Effects of Aspartic Acid against Ultraviolet A-Induced Downregulation of the Stemness of Human adipose tissue-Derived Mesenchymal Stem …
- Cellular senescence: from physiology to pathology
- RETRACTED: Chronic Inflammation: Accelerator of Biological Aging
- Senescence associated macrophages and “macroph-aging”: are they pieces of the same puzzle?
- Cellular senescence and the biology of aging, disease, and frailty
- Targeting senescent cells enhances adipogenesis and metabolic function in old age
- Urinary Iodine Concentrations in Mothers and their Term Newborns
- Aging and osteoarthritis
- Obesity-associated mechanisms of hepatocarcinogenesis
- P12 Pathological vascular smooth muscle cells remodelling in murine models of abdominal aortic aneurysm
- The aging adipose organ: lipid redistribution, inflammation, and cellular senescence
- Ginsenoside Rd attenuates the inflammatory response via modulating p38 and JNK signaling pathways in rats with TNBS-induced relapsing colitis
- Impact of cellular senescence signature on ageing research
- Metabolic and microenvironment changes in the mammary of calorie restricted, normal weight, and obese mice throughout the lifespan
- Senescent cells: a novel therapeutic target for aging and age‐related diseases
- … and Metabolic Dysfunction during Aging and Senescence: Effect of lipopolysaccharides on adipogenic potential and premature senescence of adipocyte …
- Crossing Boundaries to Propel Tissue Engineering into the Clinic
- Mitochondrial damage induces senescence with a twisted arm
- Therapeutic effect and mechanism of proanthocyanidins from grape seeds in rats with TNBS-induced ulcerative colitis
- Chronic inflammation (inflammaging) and its potential contribution to age-associated diseases
- Pathogenesis of hepatocellular carcinoma development in non-alcoholic fatty liver disease
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- Aging of the immune system: focus on inflammation and vaccination
- Molecular mechanisms of ageing and related diseases
- Senescent cells: SASPected drivers of age-related pathologies
- Control of p53 and NF-κB signaling by WIP1 and MIF: role in cellular senescence and organismal aging
- p21 both attenuates and drives senescence and aging in BubR1 progeroid mice
- Stop feeding cancer: pro-inflammatory role of visceral adiposity in liver cancer
- Cellular senescence and the senescent secretory phenotype: therapeutic opportunities
- Metabolic control of longevity
- Cisplatin-induced mesenchymal stromal cells-mediated mechanism contributing to decreased antitumor effect in breast cancer cells
- Microbiome–Obesity–Liver Cancer Interaction: Senescence of Hepatic Stellate Cells and Bile Acids Play New Roles
- Ameliorative effects of 3, 4-oxo-isopropylidene-shikimic acid on experimental colitis and their mechanisms in rats
- Hepatocellular carcinoma and lifestyles
- Inflammation and cellular senescence: potential contribution to chronic diseases and disabilities with aging
- Toll like receptor signaling in “inflammaging”: microRNA as new players
- Depleting senescent cells to combat aging
- www. aging-us. com AGING 2016, Vol. 8, Advance
- High-throughput screening reveals enzyme and GPCR targets as putative binding sites for d-deprenyl
- Adipocytes and neutrophils give a helping hand to pancreatic cancers
- Chronic senolytic treatment alleviates established vasomotor dysfunction in aged or atherosclerotic mice
- Anti-inflammatory effects of Pulvis Fellis Suis extract in mice with ulcerative colitis
- Ageing and the pathogenesis of osteoarthritis
- Aging of mice is associated with p16 (Ink4a)-and β-galactosidase-positive macrophage accumulation that can be induced in young mice by senescent cells
- Cellular senescence in aging and osteoarthritis: implications for cartilage repair
- Oxidative stress and the ageing endocrine system
- Clinical strategies and animal models for developing senolytic agents
- Liver cancer: connections with obesity, fatty liver, and cirrhosis
- Of flies, mice, and men: evolutionarily conserved tissue damage responses and aging
- Age-dependent dysregulation of innate immunity
- Endothelial progenitor cells: from senescence to rejuvenation
- Aging: a common driver of chronic diseases and a target for novel interventions
- Increased IL-6 secretion by aged human mesenchymal stromal cells disrupts hematopoietic stem and progenitor cells’ homeostasis
- Extracellular microRNAs and endothelial hyperglycaemic memory: a therapeutic opportunity?
- The role of oxidative stress and inflammation in cardiovascular aging
- Cell autonomous and non-autonomous effects of senescent cells in the skin
- A case of rheumatoid arthritis exhibiting accelerating rheumatoid pleurisy during low-dose weekly methotrexate therapy
- Mesenchymal stroma: primary determinant and therapeutic target for epithelial cancer
- The role of senescent cells in ageing
- Sowing the seeds of cancer: telomeres and age-associated tumorigenesis
- Tim-3: an emerging target in the cancer immunotherapy landscape
- Effect of traditional Chinese medicinal enemas on ulcerative colitis of rats
- Diabetes and cancer, common threads and missing links
- Hepatocellular carcinoma in nonalcoholic fatty liver: role of environmental and genetic factors
- Translational research in immune senescence: assessing the relevance of current models
- Elimination of p19ARF-expressing cells enhances pulmonary function in mice
- The effects of aging on the development of osteoarthritis
- Cellular senescence impact on immune cell fate and function
- Effects of proanthocyanidins from grape seed on treatment of recurrent ulcerative colitis in rats
- Proanthocyanidins from grape seeds modulate the NF-κB signal transduction pathways in rats with TNBS-induced ulcerative colitis
- Morphological, molecular and functional differences of adult bone marrow-and adipose-derived stem cells isolated from rats of different ages
- The role of insulin resistance in nonalcoholic steatohepatitis and liver disease development–a potential therapeutic target?
- Nonalcoholic fatty liver disease: pathogenesis and disease spectrum
- The possible mechanisms of Picrasma quassiodes (D. Don) Benn. in the treatment of colitis induced by 2, 4, 6-trinitrobenzene sulfonic acid in mice
- Aldosterone induces p21‐regulated apoptosis via increased synthesis and secretion of tumour necrosis factor‐α in human proximal tubular cells
- Senescence as a general cellular response to stress: a mini-review
- Obesity and liver cancer
- Cell senescence abrogates the therapeutic potential of human mesenchymal stem cells in the lethal endotoxemia model
- Reversing multiple age-related pathologies by controlling the senescence-associated secretory phenotype of stem cells
- Histone macroH2A1. 2 promotes metabolic health and leanness by inhibiting adipogenesis
- Pivotal role of Sirt6 in the crosstalk among ageing, metabolic syndrome and osteoarthritis
- Proanthocyanidins from grape seeds modulates the nuclear factor-kappa B signal transduction pathways in rats with TNBS-induced recurrent ulcerative colitis
- Maternal obesity programs senescence signaling and glucose metabolism in osteo-progenitors from rat and human
- Immunosurveillance of senescent cells: the bright side of the senescence program
- Obesity and the gut microbiome: pathophysiological aspects
- Ageing induced vascular smooth muscle cell senescence in atherosclerosis
- Cancer and inflammation: an old intuition with rapidly evolving new concepts
- Obesity and cancer pathogenesis
- Metabolic consequences of HIV: pathogenic insights
- Noncoding RNA control of cellular senescence
- Protective effects of 3, 4-oxo-isopropylidene-shikimic acid on experimental colitis induced by trinitrobenzenesulfonic acid in rats
- Inflammaging decreases adaptive and innate immune responses in mice and humans
- Senescence and the pro-tumorigenic stroma
- Siegesbeckia pubescens ameliorates experimental ulcerative colitis in rats by modulating PPARγ.
- Therapeutic effect of ginsenoside Rd in rats with TNBS-induced recurrent ulcerative colitis
- Mice deficient in Rbm38, a target of the p53 family, are susceptible to accelerated aging and spontaneous tumors
- Serum n3 polyunsaturated fatty acids are depleted in Crohn’s disease
- The cell secretome, a mediator of cell-to-cell communication
- Targeting senescent cells: possible implications for delaying skin aging: a mini-review
- DNA damage and innate immunity: links and trade-offs
- The Achilles’ heel of senescent cells: from transcriptome to senolytic drugs
- Protective effect of taurohyodeoxycholic acid from Pulvis Fellis Suis on trinitrobenzene sulfonic acid induced ulcerative colitis in mice
- Chronic inflammation, immune escape, and oncogenesis in the liver: a unique neighborhood for novel intersections
- Mesenchymal stem cells in regenerative medicine: focus on articular cartilage and intervertebral disc regeneration
- Interventions to slow aging in humans: are we ready?
- Anti-inflammatory activity and mechanisms of a lipid extract from hard-shelled mussel (Mytilus coruscus) in mice with dextran sulphate sodium-induced colitis
- DNA damage response and autophagy: a meaningful partnership
- NF-κB pathway activators as potential ageing biomarkers: targets for new therapeutic strategies
- mTOR signaling from cellular senescence to organismal aging
- Erdheim–Chester disease: from palliative care to targeted treatment
- Gerosuppressant metformin: less is more
- Chemoprevention of obesity-related liver carcinogenesis by using pharmaceutical and nutraceutical agents
- Workshop report Key data from the 11th International Workshop on Adverse Drug Reactions and Co-Morbidities in HIV
- Human mesenchymal stem cell-replicative senescence and oxidative stress are closely linked to aneuploidy
- Immune aging, dysmetabolism, and inflammation in neurological diseases
- Anti-inflammatory effects of Huangqin tang extract in mice on ulcerative colitis
- Conditioned media from human umbilical cord blood-derived mesenchymal stem cells inhibits melanogenesis by promoting proteasomal degradation of MITF
- Speeding up the clock: The past, present and future of progeria
- Mathematical integration of protein metabolism in growing lambs
- Short telomeres in key tissues initiate local and systemic aging in zebrafish
- Modelling age-related metabolic disorders in the mouse
- Disease drivers of aging
- Myeloma cells can corrupt senescent mesenchymal stromal cells and impair their anti-tumor activity
- Diabetes and aging
- Exercise attenuates the major hallmarks of aging
- Long noncoding RNAs in diseases of aging
- Evolving concepts in the pathogenesis of NASH: beyond steatosis and inflammation
- From cell senescence to age-related diseases: differential mechanisms of action of senescence-associated secretory phenotypes
- Persistent DNA damage‐induced premature senescence alters the functional features of human bone marrow mesenchymal stem cells
- Halofuginone reduces the inflammatory responses of DSS-induced colitis through metabolic reprogramming
- Obesity and cancer
- Senescence in human mesenchymal stem cells: functional changes and implications in stem cell-based therapy
- Bile acids and the gut microbiome
- Aging, clonality, and rejuvenation of hematopoietic stem cells
- Dysregulated inflammation as a risk factor for pneumonia in the elderly
- Ageing and the telomere connection: An intimate relationship with inflammation
- The study of skeletal aging is coming of age: A forum on aging and skeletal health
- Resveratrol attenuates senescence of adipose-derived mesenchymal stem cells and restores their paracrine effects on promoting insulin secretion of INS-1 …
- Cancer-associated-fibroblasts and tumour cells: a diabolic liaison driving cancer progression
- Nuclear lamina defects cause ATM-dependent NF-κB activation and link accelerated aging to a systemic inflammatory response
- SYSTEMIC DNA DAMAGE RESPONSE AND METABOLIC SYNDROME
- Secreted microvesicular miR‐31 inhibits osteogenic differentiation of mesenchymal stem cells
- Are there roles for brain cell senescence in aging and neurodegenerative disorders?
- Effect of Manuka honey and sulfasalazine in combination to promote antioxidant defense system in experimentally induced ulcerative colitis model in rats
- Effect of hyperglycemia on hepatocellular carcinoma development in diabetes
- NF-κB in aging and disease
- Toward the comprehensive understanding of the gut ecosystem via metabolomics-based integrated omics approach
- Interleukin‐8 production in tuberculous pleurisy: role of mesothelial cells stimulated by cytokine network involving tumour necrosis factor‐α and interleukin‐1β
- Energetic interventions for healthspan and resiliency with aging
- Secretome of human fetal mesenchymal stem cell ameliorates replicative senescence
- Caloric restriction and aging stem cells: the stick and the carrot?
- Exercise enhances wound healing and prevents cancer progression during aging by targeting macrophage polarity
- The promise of slow down ageing may come from curcumin
- Effects of mimic of manganese superoxide dismutase on 2, 4, 6-trinitrobenzene sulfonic acid-induced colitis in rats
- Genome-wide chromatin state transitions associated with developmental and environmental cues
- Oxidative stress, cellular senescence and ageing
- 7 Immune Senescence
- What Is Homeostasis?
- Atypical pyoderma gangrenosum with leukemia
- INVESTIGATING MOLECULAR PATHWAYS OF ROS-INDUCED PRO-INFLAMMATORY SENESCENCE IN PREADIPOCYTES
- Vascular wall-resident multipotent stem cells of mesenchymal nature within the process of vascular remodeling: cellular basis, clinical relevance, and …
- Recombinant HSP70 and mild heat shock stimulate growth of aged mesenchymal stem cells
- Senescence in chronic obstructive pulmonary disease
- Fibrogenesis and carcinogenesis in nonalcoholic steatohepatitis (NASH): involvement of matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinase …
- Non-alcoholic steatohepatitis and hepatocellular carcinoma: implications for lycopene intervention
- Telomeres and age-related disease: how telomere biology informs clinical paradigms
- Characterization of the human salivary proteome by capillary isoelectric focusing/nanoreversed-phase liquid chromatography coupled with ESI-tandem MS
- Macromolecular degradation systems and cardiovascular aging
- Acute phase serum amyloid A induces proinflammatory cytokines and mineralization via toll-like receptor 4 in mesenchymal stem cells
- Identification of a novel senolytic agent, navitoclax, targeting the Bcl‐2 family of anti‐apoptotic factors
- Understanding The Regulation Of Adipogenesis And Adipocyte Metabolism In Obesity
- Reprogramming suppresses premature senescence phenotypes of Werner syndrome cells and maintains chromosomal stability over long-term culture
- The senescence arrest program and the cell cycle
- The posttranslational processing of prelamin A and disease
- Caveolae and signalling in cancer
- Therapy with multipotent mesenchymal stromal cells protects lungs from radiation-induced injury and reduces the risk of lung metastasis
- Frailty and sarcopenia as the basis for the phenotypic manifestation of chronic diseases in older adults
- From experimental design to functional gene networks: DNA microarray contribution to skin ageing research
- Senescence-associated MCP-1 secretion is dependent on a decline in BMI1 in human mesenchymal stromal cells
- Tumour biology of obesity-related cancers: understanding the molecular concept for better diagnosis and treatment
- Protective effect of sanguinarine against acetic acid-induced ulcerative colitis in mice
- Living Large: What Mouse Models Reveal about Growth Hormone and Obesity
- Signaling networks determining life span
- Invariant natural killer T cells recognize a fungal glycosphingolipid that can induce airway hyperreactivity
- The second international conference “genetics of aging and longevity”
- Amniotic epithelial cells: a new tool to combat aging and age-related diseases?
- Mesenchymal stem cells in wound repair, tissue homeostasis, and aging
- The role and regulation of the nuclear factor kappa B signalling pathway in human labour
- Physiological regulation of the heat shock response by glutamine: implications for chronic low-grade inflammatory diseases in age-related conditions
- At the stem of youth and health
- New Insights into the Management and Therapeutics of Type 2 Diabetes
- Epigallocatechin-3-gallate ameliorates rats colitis induced by acetic acid
- Cellular and molecular biology of aging endothelial cells
- The nuclear lamina in health and disease
- The Biology of Aging: Role in Cancer, Metabolic Dysfunction, and Health Disparities
- Cellular and molecular basis of the imbalance between vascular damage and repair in ageing and age-related diseases: as biomarkers and targets for new …
- Interrater reliability of a clinical scale to assess knee joint effusion
- Telomeres, oxidative stress and inflammatory factors: partners in cellular senescence?
- Cell cycle arrest and the evolution of chronic kidney disease from acute kidney injury
- Biomarkers and Inflammatory Network in Aging: Targets for Therapies
- Implications of multipotent mesenchymal stromal cell aging
- Connecting the dots: from DNA damage and repair to aging
- Metformin‐mediated increase in DICER1 regulates microRNA expression and cellular senescence
- MicroRNA-34a induces endothelial progenitor cell senescence and impedes its angiogenesis via suppressing silent information regulator 1
- Identification of senescent cells in the bone microenvironment
- Identification of microRNAs dysregulated in cellular senescence driven by endogenous genotoxic stress
- Melatonin and the theories of aging: a critical appraisal of melatonin’s role in antiaging mechanisms
- Increasing longevity through caloric restriction or rapamycin feeding in mammals: common mechanisms for common outcomes?
- Extracellular microRNAs and endothelial hyperglycemic memory: a therapeutic opportunity?
- Skin mirrors human aging
- miR‐335 correlates with senescence/aging in human mesenchymal stem cells and inhibits their therapeutic actions through inhibition of AP‐1 activity
- Effect of different doses of Manuka honey in experimentally induced inflammatory bowel disease in rats
- Illuminating inflammasome activity in vivo
- Metabolic exchanges within tumor microenvironment
- Inflammation and atherosclerosis in rheumatoid arthritis
- From cellular senescence to age-associated diseases: the miRNA connection
- Melatonin reduces endoplasmic reticulum stress and autophagy in liver of leptin‐deficient mice
- Modulation of Membrane Transport Systems
- The role of chromatin reorganization in the process of cellular senescence
- Pleiotropic effects of tocotrienols and quercetin on cellular senescence: introducing the perspective of senolytic effects of phytochemicals
- Role of DNA damage in cardiovascular disease
- The telomere syndromes
- Somatic stem cell aging and malignant transformation–impact on therapeutic application
- Organelle Stress and mTOR in Aging-Associated Inflammation
- ACC 284
- Regulatory roles of miRNAs in aging
- Evidences of early senescence in multiple myeloma bone marrow mesenchymal stromal cells
- Mechanisms of metastatic tumor dormancy
- Liposarcoma
- Liposarcomas-proliferation, senescence and the role of DDIT3
- Senescence bypass in mesenchymal stem cells: a potential pathogenesis and implications of pro-senescence therapy in sarcomas
- Mechanisms of resveratrol-induced inhibition of clonal expansion and terminal adipogenic differentiation in 3T3-L1 preadipocytes
- Progressive loss of SIRT1 with cell cycle withdrawal
- Targeting Senescent Cells to Improve Human Health
- Defining mesenchymal stromal cells responsiveness to IFNγ as a surrogate measure of suppressive potency
- The germline/soma dichotomy: implications for aging and degenerative disease
- Identifying of the causative genes in spontaneous mutant mouse strains by forward-reverse genetics
- Phenylbutyric Acid: simple structure-multiple effects
- The role of immunosenescence in the development of age-related diseases
- Melatonin reverses H2O2‐induced premature senescence in mesenchymal stem cells via the SIRT1‐dependent pathway
- Recent advances in mouse models of obesity-and nonalcoholic steatohepatitis-associated hepatocarcinogenesis
- Cellular senescence and vascular disease: novel routes to better understanding and therapy
- Telomeres, NAFLD and chronic liver disease
- The emergence of geromirs: A group of micrornas implicated in aging
- The Role of Stem Cell Genomic Instability in Aging
- Potential therapeutic effects of curcumin, the anti-inflammatory agent, against neurodegenerative, cardiovascular, pulmonary, metabolic, autoimmune and neoplastic …
- Regulation of senescence by microRNA biogenesis factors
- Host resistance and immune aging
- Coming of age: molecular drivers of aging and therapeutic opportunities
- ISSN 0975-413X CODEN (USA): PCHHAX
- Finding Ponce de Leon’s Pill: challenges in screening for anti-aging molecules
- Thymic involution perturbs negative selection leading to autoreactive T cells that induce chronic inflammation
- An Arf-Egr-C/EBPβ pathway linked to ras-induced senescence and cancer
- Growth hormone is a cellular senescence target in pituitary and nonpituitary cells
- MicroRNAs linking inflamm-aging, cellular senescence and cancer
- Ionizing radiation promotes the acquisition of a senescence-associated secretory phenotype and impairs angiogenic capacity in cerebromicrovascular endothelial …
- Medial arterial calcification: an overlooked player in peripheral arterial disease
- Lessons from Hepatocyte-Specific Cyp51 Knockout Mice: Impaired Cholesterol Synthesis Leads to Oval Cell-Driven Liver Injury
- Senescence-associated secretory phenotype contributes to pathological angiogenesis in retinopathy
- Inflammasomes: guardians of cytosolic sanctity
- As we age: Does slippage of quality control in the immune system lead to collateral damage?
- Anti-aging pharmacology: promises and pitfalls
- Neovascularization capacity of mesenchymal stromal cells from critical limb ischemia patients is equivalent to healthy controls
- Effect of hyperglycemia on hepatocellular carcinoma development in diabetes
- Expression of HOXD9 in fibroblast-like synoviocytes from rheumatoid arthritis patients
- The Disrupted Steady-State: Tipping the Balance in Favour of Cancer
- The Way Forward: Translation
- Intervention of aging and its effects on cellular health
- DNA damage response and immune defense: links and mechanisms
- Towards an evidence-based model of aging
- iPSCs as a major opportunity to understand and cure age-related diseases
- The biology of aging: 1985–2010 and beyond
- DNA damage: from chronic inflammation to age-related deterioration
- The emerging role of Notch pathway in ageing: focus on the related mechanisms in age-related diseases
- SPEAKER ABSTRACTS
- miR-29c-3p promotes senescence of human mesenchymal stem cells by targeting CNOT6 through p53–p21 and p16–pRB pathways
- Osteopontin, a key mediator expressed by senescent pulmonary vascular cells in pulmonary hypertension
- NF-κB signaling as a driver of ageing
- The Cellular Senescence Program
- Age-related changes in blood-brain barrier integrity in C57BL/6J mice
- Ultrastructural analysis of changes in neurons of the mouse internal anal sphincter during ageing
- Age-related changes to lumbosacral spinal cord motoneurons that modulate bladder and bowel functions in male C57BL/6 mice
- The metabolic regulation of cellular ageing
- The inflammatory network: bridging senescent stroma and epithelial tumorigenesis
- Cellular senescence and inflammation in aging and age-related disease
- Influence of aging on the quantity and quality of human cardiac stem cells
- Prospects and challenges for the use of stem cell technologies to develop novel therapies for Parkinson disease
- Hypoxia-inducible histone lysine demethylases: impact on the aging process and age-related diseases
- Autophagy and cancer metabolism
- Assessing cell and organ senescence biomarkers
- Sphingolipids in inflammation: pathological implications and potential therapeutic targets
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- Metformin and the ATM DNA damage response (DDR): accelerating the onset of stress-induced senescence to boost protection against cancer
- Cellular senescence in cardiovascular diseases: potential age-related mechanisms and implications for treatment
- Insulin-like growth factor binding proteins 4 and 7 released by senescent cells promote premature senescence in mesenchymal stem cells
- Pathogenesis of osteoarthritis
- Better living through chemistry: caloric restriction (CR) and CR mimetics alter genome function to promote increased health and lifespan
- Perspectives on translational and therapeutic aspects of SIRT1 in inflammaging and senescence
- Intestinal anti-inflammatory effect of the rhizome extracts of Menispermum dauricum DC. on trinitrobenzene sulfonic acid induced ulcerative colitis in mice
- Biosprays: From the biomedical to the clinical sciences
- Influence of age and physical fitness on miRna-21, TGF-ß and its receptors in leukocytes of healthy women.
- Caspase inhibition switches doxorubicin-induced apoptosis to senescence
- MicroRNAs as mediators of the ageing process
- Modelling ageing and age-related disease
- PROTECTIVE EFFECT OF RICE BRAN WATER EXTRACT ON PANCREAS OF RATS FED A HIGH-FAT DIET
- New objective findings after whiplash injuries: high blood flow in painful cervical soft tissue: an ultrasound pilot study
- Genome integrity in aging: human syndromes, mouse models, and therapeutic options
- Conditioned medium derived from rat amniotic epithelial cells confers protection against inflammation, cancer, and senescence
- Endothelial cell senescence and thrombosis: ageing clots
- A Fungal Glycosphingolipid Directly Activates Natural Killer T Cells and Rapidly Induces Airways Disease
- NAFLD and hepatocellular Carcinoma: how big a problem is this really?
- Mast cells and histamine are triggering the NF-κB-mediated reactions of adult and aged perilymphatic mesenteric tissues to acute inflammation
- Oral submucous fibrosis: Review on mechanisms of pathogenesis and malignant transformation
- Extracellular vesicles in lung microenvironment and pathogenesis
- Vascular endothelial senescence: from mechanisms to pathophysiology
- Autoimmune atherosclerosis in 3D: how it develops, how to diagnose and what to do
- Physiological roles of the DNA demethylation-associated proteins Gadd45a and Ing1
- Stress-induced premature senescence of endothelial and endothelial progenitor cells
- Regulation of Senescence by microRNAs
- Muscle stem cell aging: regulation and rejuvenation
- kk journal of experimental biology.
- 2.20 Behcet’s disease and miscellaneous rheumatic conditions
- Inflammatory bowel disease part I: ulcerative colitis–pathophysiology and conventional and alternative treatment options
- The Buck Institute: An inside look
- Accelerated epithelial cell senescence in IPF and the inhibitory role of SIRT6 in TGF-β-induced senescence of human bronchial epithelial cells
- Orphan technology: Unfunded early-stage bioscience is dropped off at the firehouse
- Computational approaches for the transcriptomics, proteomics and epigenetic analysis in adult stem cells
- The secret lives of stem cells: Unraveling the molecular basis of stem cell aging
- Positive and negative effects of cellular senescence during female reproductive aging and pregnancy
- Global profiling and relative quantifiction of histones, histone PTMs and histone-modifying enzymes in mesenchymal stem cells using LC-MS/MS and a novel …
- The 10th World Congress on Inflammation
- Ms. No.: METHODS-D-15-00125 R1–Revised Version
- Are aging biomarkers clinically relevant in oncogeriatrics?
- Apocrine secretion: new insights into an old phenomenon
- Molecular links between cellular senescence, longevity and age-related diseases–a systems biology perspective
- Practical Laboratory Medicine
- Stop Aging Disease! ICAD 2014.
- PROGRESS REPORT ON THE ROLE OF MITOCHONDRIAL ISOCITRATE DEHYDROGENASE 2 IN AGE-RELATED HEARING LOSS IN MICE
- Impact of physical activity on immune function and inflammation in the elderly
- Four faces of cellular senescence
- Interventions to slow aging in humans: Are we ready?
- Determination of serum visfatin level in patients with Behcet disease, comparing with normal population
- Senescent fibroblast-derived Chemerin promotes squamous cell carcinoma migration
- DNA damage: a main determinant of vascular aging
- The Role of Estrogen Deficiency in Skin Aging and Wound Healing
- Comparative analysis of gene expression data reveals novel targets of senescence-associated microRNAs
- Accelerated telomere shortening in acromegaly; IGF-I induces telomere shortening and cellular senescence
- Salvianolic acid B restored impaired barrier function via downregulation of MLCK by microRNA-1 in rat colitis model
- IL-6 and related cytokines as the critical lynchpins between inflammation and cancer
- Anti-stress gene response in cell and tissue ageing: role of transcription factor NF-E2-related factor-2 and effect of dietary activators
- Protective Effect of Paronychia argentea L. on Acetic Acid Induced Ulcerative Colitis in Mice by Regulating Antioxidant Parameters and Inflammatory Markers
- 7th Joint Meeting of the European Tissue Repair Society (ETRS) with the Wound Healing Society
- Human Amniotic Fluid Mesenchymal Stromal cells (AF-MSCs) are Less Prone to in vitro Senescence Process Compared with Bone Marrow MSCs
- The central role of muscle stem cells in regenerative failure with aging
- Modulation of ageing characteristics with an anti-ageing compound
- Insulin pathway and its correlation with ageing and longevity
- Glucocorticoids suppress selected components of the senescence‐associated secretory phenotype
- Altered glycolipid and glycerophospholipid signaling drive inflammatory cascades in adrenomyeloneuropathy
- Stem cells and cancer stem cells
- Nutritional Modulators of Cellular Senescence In Vitro
- Non‐cell autonomous or secretory tumor suppression
- The Aging Superorganism
- Systemic problems: a perspective on stem cell aging and rejuvenation
- Modulators of cellular senescence: mechanisms, promises, and challenges from in vitro studies with dietary bioactive compounds
- Pharmacotherapeutics ECG of the Month
- Molecular Mechanisms of Lycopene Actions on Liver Disease Outcomes
- Pathophysiological fundamentals of diabetic cardiomyopathy
- The gut microbial endocrine organ: bacterially derived signals driving cardiometabolic diseases
- The role of miRNAs in common inflammatory arthropathies: osteoarthritis and gouty arthritis
- Similarities in gene expression profiles during in vitro aging of primary human embryonic lung and foreskin fibroblasts
- Rescuing the regenerative capacity of human mesenchymal stem cells from the elderly
- Nuclear lamina defects cause ATM-dependent NF-κB activation and link accelerated aging to a systemic inflammatory response
- Nuclear lamina defects cause ATM-dependent NF
- Interventions for age-related diseases: Shifting the paradigm
- An Arf-Egr-C
- Biomolecular bases of the senescence process and cancer. A new approach to oncological treatment linked to ageing
- Aging, Immunosenescence, and Cancer
- A causal role of ATM-and NEMO-dependent NF-κB activation in DNA damage-induced senescence and aging
- Effect of bisphenol A on stress-induced premature senescence
- Progerin Expression Disrupts Critical Adult Stem Cell Functions that Mediate Tissue Repair Primarily through a Mechanism that Permanently Farnesylates Lamin A
- Systemic DNA damage responses in aging and diseases
- Osteoarthritis in the Elderly
- MDM2 levels modulate the cellular senescence response to CDK4 inhibition
- Functional-structural plant modeling
- Placental origins of chronic disease
- Inflammatory dysregulation and cancer: From molecular mechanisms to therapeutic opportunities
- The Role of Integrated Omics in Elucidating the Gut Microbiota Health Potentials
- Allogeneic mesenchymal stem cells transplantation in patients with refractory RA
- Stress-Induced Senescence: Molecular Pathways
- Neovascularization capacity of mesenchymal stromal cells from critical limb ischemia patients is equivalent to healthy controls
- Twist proteins as oxidative and hypoxic stress regulators
- The gut microbiota and the liver: implications for clinical practice
- The Epigenome and Aging
- Protein expression analysis of rat testes induced testicular toxicity with several reproductive toxicants
- Glenn Workshop on the Biology of Aging and AFAR Grantee Conference| JOINT MEETING
- The hallmarks of fibroblast ageing
- Signaling Networks Controlling Cellular Senescence
- Evidences of Early Senescence in Multiple Myeloma Bone Marrow
- Systemic administration of WY-14643, a selective synthetic agonist of peroxisome proliferator activator receptor-alpha, alters spinal neuronal firing in a rodent model of …
- Development of a mouse model for Hutchinson-Gilford progeria syndrome reveal defects in adult stem cell maintenance
- A potential role for miR-31 in osteoblastic transition of vascular smooth muscle cells and cortisol-induced osteoporosis
- Senescent mesenchymal stem cells promote colorectal cancer cells growth via galectin-3 expression
- BLT2 Protects Skin from the Damage Caused by Type 2 Diabetes Hyperglycemia by Increasing NO Production Through the nNOS Expression
- Molecular mechanisms of aging in MTDNA mutator mice
- Reversing stem cell aging: Implications for vascular regeneration
- Targeting the tumor stroma as a novel therapeutic approach for prostate cancer
- The Role of Macrophage Migration Inhibitory Factor in Osteoarthritis
- Evidence supporting the utility of blood cell respiratory capacity as a systemic marker of mitochondrial health and biological age
- Circadian molecular clock in lung pathophysiology
- Stop Aging Disease! ICAD 2014
- Investigating the differential instructive roles of WT1’s isoforms
- Osteoporosis and mechanisms of skeletal aging
- Functional Enrichment Analysis
- mberHappily (n) ever after: Aging in the context of oxidative stress, proteostasis loss and cellular senescence
- Skin disease in laminopathy-associated premature aging
- Cellular and Molecular Mechanisms of Chronic Inflammation in Aging of Skeletal Muscle
- Oxidative stress-induced JNK activation contributes to proinflammatory phenotype of aging diabetic mesangial cells
- Histone methylation and aging: lessons learned from model systems
- Regulation of Phospholipase Isozymes by Nuclear Factor-κB in Human Gestational Tissues in Vitro
- Fluorescence Spectroscopy
- Psoriasis and inflammatory bowel disease: links and risks
- Prelamin A accelerates vascular calcification via activation of the DNA damage response and senescence-associated secretory phenotype in vascular smooth muscle …
- SIRT1 in endothelial cells as a novel target for the prevention of early vascular aging
- Cellular senescence as the causal nexus of aging
- MicroRNAs Regulate p21Waf1/Cip1 Protein Expression and the DNA Damage Response in Human Embryonic Stem Cells
- Basic Research
- Nuclear matrix, nuclear envelope and premature aging syndromes in a translational research perspective
- Relationships Among Body Mass Index, Nutrition, Internalizing Symptoms, and Ethnic Identity of Cherokee Youth Attending a Private American Indian Secondary …
- The role of the stress response gene Gadd45b in senescence
- False discovery rate (FDR)
- FBA Analysis, Plant-Pathogen Interactions
- Influence of aging on proliferation, pluripotency, immunogenic profiles from bone marrow mesenchymal stem cells
- Macrophage migration inhibitory factor regulates AKT signaling in hypoxic culture to modulate senescence of human mesenchymal stem cells
- Cell and molecular aging
- Loss of HuR leads to senescence-like cytokine induction in rodent fibroblasts by activating NF-κB
- Role of the nuclear envelope in regulation of ageing
- Chemotherapy-and Radiation-Induced Accelerated Senescence: Implications for Treatment Response, Tumor Progression and Cancer Survivorship
- Selenium and Senescence: Centering on Genome Maintenance
- Author statement
- Mechanisms of action of anti-TNF-α antibodies in inflammatory bowel disease
- Immortality: Myth or becoming Reality
- Skin, Mucosa and Menopause
- SUPPLEMENTARY TABLES
- Proteome analysis of formalin-fixed and paraffin-embedded tissue
- Framework Region (FR-IMGT)
- Frequent Pattern Mining
- Founders Effect
- Fisher’s Test
- Frequency
- Frequentist Approach
- Fitness
- Forward-scattered Light (FSC)
- Fluorescent Markers
- Fluorescence Microscopy
- Functional/Signature Network Module for Target Pathway/Gene Discovery
- Forward and Inverse Parameter Estimation for Metabolic Models
- Feature Selection
- Fitness Function
- Feedback Regulation
- Fibroblasts
- Feasibility
- Functional Modules and Complexes
- FunctionalityType
- Flux Balance Analysis
- Fokker–Planck Equation
- Faceted Browsing
- Fluorescence-activated Cell Sorting
- Flow Cytometry
- Frame Language
- Function, biological
- Feed Forward Loop
- Fluorophore
- Fluorescence Microscope
- False Positive Rate
- Fuzzy Logic
- Functional
- Flux Control Coefficient
- Fluorescence
- Functor
- Fourier Transform Infrared Microspectroscopy (FTIR)
- FuGE
- Foundational Model of Anatomy
- Floquet Multiplier
- Function, Distributed
- 9.1 Gut Microbiota
- Ageing and inflammation with focus on end-stage renal diseases: genetic and epigenetic factors
- The pleiotropic effects of HMG-CoA reductase inhibitors in inflammatory arthritis
- Assessing Pain and Inflammation in Arthritis Using Novel Imaging Methods
- The skin as a mirror of the aging process
- Hyperalgesia and allodynia to superficial and deep-tissue mechanical stimulation within and outside of the UVB irradiated area in human skin
- IL-6 secreted from senescent mesenchymal stem cells promotes proliferation and migration of breast cancer cells
- The role of telomere damage in cardiomyocyte ageing
- Gut Microbiota and HCC
- Contributions of telomere biology to human age-related disease
- Adult cardiac stem cells: identity, location and potential
- Human Population Studies of Transcriptome-wide Expression in Age-related Traits
- The Role of Age in Cellular Responses to Microenvironmental Cues as a Breast Cancer Susceptibility Factor
- The effects of chronic and acute toxicological exposures on the expression of the tumor suppressor p16INK4a
- p53 and NF-κB: different strategies for responding to stress lead to a functional antagonism
- P13. 2
- The role of mitochondria in the regulation of gamma rays induced mTOR-dependent senescence
- Regulation of Forkhead BOX O tumor suppressors by Reactive Oxygen Species
- CSI-01–Cell Cycle & Checkpoints
- A novel approach towards finding regulatory microRNAs during phagosomal maturation in infection.
- The Impact of Physical Activity and Antioxidants on Tumor-Skeletal Muscle Crosstalk during Cancer: Deciphering Signaling Pathways Involved in Tumor Growth and …
- Par Proteins in Tumor Formation and Progression
- Identification and characterization of senescence-associated microRNAs in a mouse model of the XFE Progeroid Syndrome
- Immunoregulatory network and cancer-associated genes: molecular links and relevance to aging
- Ionizing radiation-mediated premature senescence and paracrine interactions with cancer cells enhance the expression of syndecan 1 in human breast …
- Telomere fragment induced amnion cell senescence: a contributor to parturition?
- Islet Biology/Insulin Secretion
- Telomere dysfunction: Role in arterial aging and hypertension
- Colorectal cancer-promoting activity of the senescent peritoneal mesothelium
- Senescent Carcinoma Associated Fibroblasts Up-regulate Interleukin 8 to Enhance Pancreatic Cancer Progression
- MOVD 2013
- The Role of Prolactin in the Cellular Response to DNA Damaging Agents
- Studies on the Developmental Changes in Parvalbumins of the Catfish, Heteropneustes fossilis (Bloch)
- Forum on aging and skeletal health: summary of the proceedings of an ASBMR workshop
- Analysis of temporal gene expression during Bacillus subtilis spore germination and outgrowth
- Analysis of gene expression during aging of CGNs in culture: implication of SLIT2 and NPY in senescence
- HIF1α regulates Mitochondrial biogenesis and Cellular senescence induced by Gamma Radiation
- Roles of senescence escape and epigenetic modifications in liver cancer
- Autophagy and inflammation in the pathogenesis of idiopathic dilated cardiomyopathy
- Interventions for age-related diseases: shifting the
- Differential expression of cellular senescence markers in the assessment of breast cancer development
- Pleiotropic cellular functions of PARP1 in longevity and aging: genome maintenance meets inflammation
- The role of Inhibitor of DNA binding 4 (Id4) in mammary gland development and breast cancer
- The Role of Photodynamic Therapy in Wound Healing and Scarring in Human Skin
- Melatonin maintains mitochondrial membrane potential and attenuates activation of initiator (casp‐9) and effector caspases (casp‐3/casp‐7) and PARP in UVR …
- Pathogenesis of intervertebral disc degeneration
- Thymic involution perturbs negative selection and leads to chronic inflammation
- Elucidating Molecular Changes in CD8+ T cells During Aging
- High-throughput Screening of Age-related Changes in Caenorhabditis elegans
- Causes, consequences, and reversal of immune system aging
- Senescence and apoptosis: dueling or complementary cell fates?
- Frequency of the cancer-resistant phenotype in SR/CR mice and the effect of litter seriation
- Understanding the roles of Non-homologous end joining and p53 after DNA damage
- IGF-binding protein 2–oncogene or tumor suppressor?
- Regulatory Mechanisms of NK-Cell-Mediated Immune Surveillance of Senescent Cells
- Suppression of autophagy during liver regeneration impairs energy charge and hepatocyte senescence in mice
- Mechanisms of tissue injury in autoimmune liver diseases
- Telomere dysfunction and senescence in the ageing lung and age-related lung disease
- HDAC 1 inhibition by melatonin leads to suppression of lung adenocarcinoma cells via induction of oxidative stress and activation of apoptotic pathways
- Poster session 3
- The senescent cell induced bystander effect
- The Function and Regulation of Senescent Stromal-Derived Osteopontin
- Effects of chemotherapy and radiotherapy in rectal cancer: significance of different cellular outcomes in tumor behavior
- Polycomb Repressive Complex 1 Coordinates Enhanced Replication and Transcription in Transit Amplifying Chondrogenic Progenitors.
- Molecular Tuning Of Telomerase Activity In Senescent Human T Cells
- Role of squamous cell carcinoma antigen (SCCA) in oncogenic Ras-mediated tumorigenesis
- Increased oxidative and nitrative stress accelerates aging of the retinal vasculature in the diabetic retina
- The role of calcification regulatory proteins in the arterial stiffening of chronic kidney disease stages 3 & 4
- Age-like Phenotype of Microglia During HIV-1 Infection
- Characterisation of the molecular and functional changes
- The biology of aging: implications for diseases of aging and health care in the twenty-first century
- Cytokine and nitric oxide production in inflammatory arthritis
- Anti-Aging Effects of the Transcendental Meditation Program: Analysis of Ojas Level and Global Gene Expression
- Investigating the chondrogenic phenotype in clinically relevant cells: the effect of hTERT expression
- The diet-microbiota-metabolite axis regulates the host physiology
- Role of stromal fibroblasts in prostate carcinoma progression and metabolic reprogramming of cancer cells
- Regulation and inhibition of pro-tumorigenic microenvironments
- Metal-induced oxidative stress in human fibroblasts: A role in cellular ageing
- EVALUATING THE ROLE OF NF-êB SUPPRESSION IN AMELIORATING MAMMALIAN DISEASE: AN EXAMINATION OF INFLAMMATORY BOWEL DISEASE AND …
- Session held on 9 July 2016
- MAD2 depletion triggers premature cellular senescence in human primary fibroblasts by activating a p53 pathway preventing aneuploid cells propagation
- Molecular mechanism underlying the tumor-promoting functions of carcinoma-associated fibroblasts
- Understanding the pathophysiology and challenges of development of medical countermeasures for radiation-induced vascular/endothelial cell injuries: report of a …
- Regulation and Inhibition of Pro-Tumorigenic Microenvironments
- Changes in DNA methylation patterns in mammals with senescence, ageing and energy restriction
- Methamphetamine accelerates cellular senescence and aging through CYP2D-dependent stimulation of ceramide biosynthesis
- Program Committee: Sabine Fleming Markus Boehm Knut Schaekel Martin Metz Thomas Tueting
- Muscle ageing and anabolic response in the context of healthy and chronically HIV infected individuals
- Pathway Profiling Of Replicative And Induced Senescence
- Role of Tumor Suppressor DMP1 in the Initiation and Progression of Breast Cancer
- Revista de
- Endogenous retroelements in cellular senescence and related pathogenic processes: promising drug targets in age-related diseases
- Interactions between mitochondria and inflammatory factors during cellular senescence
- Using drug treatments to control genome behaviour in normal and Hutchinson-Gilford Progeria Syndrome fibroblasts, with and without hTERT immortalisation
- The chronic lymphocytic leukemia clone disrupts the bone marrow microenvironment
- Understanding vascular diseases: lessons from premature aging syndromes
- Epigenetic mechanisms of longevity and aging
- The role of DNA damage and repair in aging through the prism of Koch-like criteria
- Nutritional roles of selenium in cellular and mouse aging
- Anisotropy in the anodic oxidation of silicon in KOH solution
- Tumor Microenvironment
- Investigating the role of DNA polymerase beta in the aging phenotype of Down syndrome
- Diamond Sponsor
- EXTRACELLULAR MATRIX PROTEINS AND EPITHELIAL CELL PLASTICITY IN PROGRESSION OF BREAST AND PROSTATE CANCER
- Noncoding RNA in age-related cardiovascular diseases
- Identification and characterisation of telomere regulatory and signalling pathways after induction of telomere dysfunction
- Activity and controlled delivery of epigallocatechin 3-gallate in the treatment of degenerative disc disease
- State-of-the-Art Lecture
- Whose place is it?: examining the socio-spatial geography of obesity in young adults for an Australian context.
- Tumor Promoting Aspects of Senescence in Cancer Progression
- Long noncoding RNA H19 mediates melatonin inhibition of premature senescence of c‐kit+ cardiac progenitor cells by promoting miR‐675
- Higher-Order Unfolding of Peri/Centric Satellite Heterochromatin is an Early and Consistent Event in Cell Senescence: A Dissertation
- Poster session 2
- Hallmarks of progeroid syndromes: Lessons from mice and reprogrammed cells
- Proinflammatory cytokines in breast cancer: mechanisms of action and potential targets for therapeutics
- Nitrous oxide analgesia for bone marrow aspiration and biopsy–A randomized, controlled and patient blinded study
- 15th International Biennial Congress of the METASTASIS RESEARCH SOCIETY
- PLATFORM PRESENTATIONS
- The Genetic Landscapes of Inflammation-Driven Gastrointestinal Tract Cancers
- The senescent microenvironment promotes the emergence of heterogeneous cancer stem-like cells
- Mutual Reinforcement Between Telomere Capping and Canonical Wnt Pathway Activity in the Intestinal Stem Cell Niche
- The role of nitrosative and metabolic stress in vascular cell senescence
- Expression of p16INK4a in peripheral blood T‐cells is a biomarker of human aging
- MMP-2, MMP-9 production was significantly elevated by fibroblast cells isolated from rheumatoid arthritis patient when co-cultured with monocyte (THP-1) with …
- Evaluating the physiological reserves of older patients with cancer: the value of potential biomarkers of aging?
- POSTER PRESENTATIONS-Sunday, December 7
- Array-based transcriptional analysis of Clostridium sporogenes UC9000 during germination, cell outgrowth and vegetative life
- Pancreatic Dysfunction in Shwachman-Diamond Syndrome
- The wound healing, chronic fibrosis, and cancer progression triad
- Senescence suppressors: their practical importance in replicative lifespan extension in stem cells
- Contributions of Activated Hepatic Stellate Cells to Hepatocarcinogenesis
- Principles of Medical Management of Ulcerative Colitis
- Proceedings of the 26th annual meeting Chiba, Japan, October 18–20, 1984
- Roles of the ING1 Epigenetic Regulator in Breast Cancer
- Directions in Post-Traumatic Arthritis
- Metabolic regulation of intestinal stem cell function in Drosophila melanogaster
- Senescent endothelial cells: Potential modulators of immunosenescence and ageing
- Genotype distribution-based inference of collective effects in genome-wide association studies: insights to age-related macular degeneration disease …
- Sustained low-dose treatment with the histone deacetylase inhibitor LBH589 induces terminal differentiation of osteosarcoma cells
- The multiple roles of A-type lamins in cellular aging, cell cycle progression and the DNA damage response.
- Loss of the osteogenic differentiation potential during senescence is limited to bone progenitor cells and is dependent on p53
- Podocyte Injury Causes Chronic Kidney Disease in the Ercc1 Deficient Mouse Model of Accelerated Aging
- Biological ageing, inflammation and nutrition: how might they impact on systemic sclerosis?
- Detection of mesenchymal stem cells senescence by prelamin A accumulation at the nuclear level
- The role of chondrocyte senescence in osteoarthritis
- A senescent cell bystander effect: Senescence‐induced senescence
- Changes in regenerative capacity through lifespan
- Cancer, Senescence, and Aging: Translation from Basic Research to Clinics
- Accumulation of spontaneous γH2AX foci in long-term cultured mesenchymal stromal cells
- Extracellular matrix and liver disease
- Programmed cell senescence during mammalian embryonic development
- Role of MicroRNA-146a in Vascular Inflammation and Atherosclerosis
- The effect of radiation on cellular ageing
- Programmed cell death in aging
- Update on the mechanisms of action of anti‑TNF‑α antibodies and their clinical implications in inflammatory bowel disease
- Clinical Investigation Program RCS-MED-300 (R1)
- Analysis of Temporal Gene Expression
- Postnatal Hdac3 deficiency in chondrocytes alters cortical bone architecture and increases articular cartilage thickness with age
- EMT and oxidative stress: a bidirectional interplay affecting tumor malignancy
- Regulation of 11β-Hydroxysteroid Dehydrogenase Type 1 and 2 in Rheumatoid Arthritis
- Impacts of Aging and Inflammation on Mycobacterium tuberculosis Control
- A review of melatonin as a suitable antioxidant against myocardial ischemia–reperfusion injury and clinical heart diseases
- Long noncoding RNAs (lncRNAs) and the molecular hallmarks of aging
- Integrative analysis of longevity, age-related diseases and aging-associated processes: Construction of the NetAge database
- SNEVPrp19/PSO4 deficiency increases PUVA‐induced senescence in mouse skin
- miR‐17, miR‐19b, miR‐20a, and miR‐106a are down‐regulated in human aging
- Pašatjaunošanās un paātrinātas novecošanās attiecības normālās un vēža šūnās pēc DNS bojājuma
- Circulating microRNAs as novel biomarkers for bone diseases–Complex signatures for multifactorial diseases?
- Aldehyde dehydrogenase activity of breast cancer stem cells is primarily due to isoform ALDH1A3 and its expression is predictive of metastasis
- Time-and Concentration-dependent response of a liver cell line to Benzo (a) pyrene
- Practical alternatives to chronic caloric restriction for optimizing vascular function with ageing
- Manipulation du métabolisme énergétique dans les leucémies aiguës myéloïdes: mitochondrie, apoptose et mécanisme d’action de la metformine
- Insulin-like growth factor binding protein-6 delays replicative senescence of human fibroblasts
- Intervention in Genotoxic Stress–Induced Senescence by Cordycepin Through Activation of eIF2α and Suppression of Sp1
- p62: linking protein homeostasis and the DNA damage response during ageing
- Molecular basis of Osteoarthritis and aspects of cellular senescence in disease
- Etude du facteur de réparation de l’ADN, Xeroderma pigmentosum du groupe C (XPC), dans les cellules souches hématopoïétiques
- HIV-1 Infection, Antiretroviral Therapies, and HIV-Associated Atherosclerosis
- The role of the transcriptional regulation of stromal cells in chronic inflammation
- Cell ageing: a flourishing field for neurodegenerative diseases
- Senescence of bone marrow mesenchymal stromal cells is accompanied by activation of p53/p21 pathway in myelodysplastic syndromes
- Rat retinal transcriptome: effects of aging and AMD-like retinopathy
- Aging of the liver: what this means for patients with HIV
- Pharmacology and biochemistry of salicylates and related drugs
- A report to inform the development of a clinical practice guideline for rehabilitation post total knee arthroplasty in a South African public hospital
- Nutrigerontology: why we need a new scientific discipline to develop diets and guidelines to reduce the risk of aging‐related diseases
- Cellular responses to zinc involving the transcription factor ZNF658 and its target genes
- Determining the role of scavenger receptor class B type I as a source of cholesterol for de novo androgen synthesis in castration-resistant prostate cancer
- Antioxidant properties of mesalamine in colitis inhibit phosphoinositide 3-kinase signaling in progenitor cells
- Aging and the Host Response to Implanted Biomaterials
- A role for epigenetics in aging and the age-dependent response to ionizing radiation
- Interleukin 6 signaling regulates promyelocytic leukemia protein gene expression in human normal and cancer cells
- Mechanisms of microRNAs in atherosclerosis
- Mechanisms of Ageing and Development
- Telomeres and telomerase: their mechanisms of action and the effects of altering their functions
- Lifespan‐extending caloric restriction or m TOR inhibition impair adaptive immunity of old mice by distinct mechanisms
- Fourth International Ankle Symposium, July 16–18, 2009, Sydney, Australia
- Telomeres, Aging, and Nutrition
- Perspectives in pain research 2014: neuroinflammation and glial cell activation: the cause of transition from acute to chronic pain?
- On the Role of Prelamin A in the Heart
- Therapeutic effects and the underlying mechanisms of qing-dai powder against experimental colitis in mice
- Role of Gut Microbiome in the Modulation of Environmental Toxicants and Therapeutic Agents
- 43nd Annual Meeting of the Arbeitsgemeinschaft Dermatologische Forschung eV (ADF)
- furanosidase f
- Stellate cells
- Pressure and cold pain threshold reference values in a large, young adult, pain-free population
- The ENRGISE Pilot Study Protocol
- A Comparative Analysis of Stress Granule Assembly in Replicative and Stress-Induced Premature Senescence
- Mutant lamin A links prophase to a p53 independent senescence program
- Identification and characterization of downstream effector protein (s) regulated by p53 and pRb
- Long-term efficacy of spironolactone on pain, mood, and quality of life in women with fibromyalgia: An observational case series
- Telomere shortening and immune activity in war veterans with posttraumatic stress disorder
- KAROLINSKA INSTITUTET, STOCKHOLM, SWEDEN
- Interplay between the myc oncoprotein, cyclin-dependent kinases and e3 ubiquitin ligases
- Calcitonin gene-related peptide (CGRP) in age-associated vascular inflammation and leukocyte trafficking
- The Contribution of DNA Interstrand Crosslinks to Aging
- ART. IV.–A Statistical Contribution to our knowledge of Abscess, and other Diseases Consequent upon the Lodgment of Foreign Bodies in the Appendix Vermiformis …
- Molecular Mechanisms of Cancer Progression: The Central Role of the Retinoblastoma Family Members
- Determination of Autoantibody IgG Subclass and Partial Sequence using Multi-affinity Purification with Multi-enzymatic Digestion by LC-MS
- Investigating the role of mitochondrial respiratory chain activity and mitochondrial DNA damage in skin ageing
- Prevalence of lumbo-pelvic pain and factors associated with it in cyclists in Johannesburg
- Health Ballistics: Multiple Reference Point Informed Probability Theory
- Translational Science 2014 Meeting Abstracts
- Proteomic profiling following cryopreservation
- Functional interaction between FOXO4 and p53 in response to oncogenic BRAF signaling
- Translational Science 2014 Meeting Abstracts
- Mechanism of Tumorigenesis by Cancer-Associated Mutations of INI1/SMARCB1, a Component of the SWI/SNF Chromatin Remodeling Complex
- Ecology of juvenile salmon in shallow tidal freshwater habitats in the vicinity of the Sandy River delta, lower Columbia River, 2008
- The role of bone morphogenetic protein 4 in the pathogenesis of choroidal neovascularization in age-related macular degeneration
- The ominous triad of adipose tissue dysfunction: inflammation, fibrosis, and impaired angiogenesis
- Sarcopenic obesity or obese sarcopenia: a cross talk between age-associated adipose tissue and skeletal muscle inflammation as a main mechanism of the …
- Cellular Senescence Biomarker p16INK4a+ Cell Burden in Thigh Adipose is Associated With Poor Physical Function in Older Women
- Expansion of adipose tissue‐derived stromal cells at “physiologic” hypoxia attenuates replicative senescence
- Age-induced changes in white, brite, and brown adipose depots: a mini-review
- adipose tissue inflammation in aging
- Rare progerin-expressing preadipocytes and adipocytes contribute to tissue depletion over time
- Cellular aging contributes to failure of cold-induced beige adipocyte formation in old mice and humans
- Healthy ageing in 2016: Obesity in geroscience—is cellular senescence the culprit?
- Micro-RNAS regulate metabolic syndrome-induced senescence in porcine adipose tissue-derived mesenchymal stem cells through the P16/MAPK pathway
- Therapeutic doses of doxorubicin induce premature senescence of human mesenchymal stem cells derived from menstrual blood, bone marrow and adipose tissue
- Growth hormone’s effect on adipose tissue: quality versus quantity
- Aging, cell senescence, and chronic disease: emerging therapeutic strategies
- Neovascular deterioration, impaired NADPH oxidase and inflammatory cytokine expression in adipose-derived multipotent cells from subjects with metabolic …
- Dietary restriction ameliorates age-related increase in DNA damage, senescence and inflammation in mouse adipose tissuey
- Fisetin is a senotherapeutic that extends health and lifespan
- adipose tissue-derived extracellular fraction characterization: biological and clinical considerations in regenerative medicine
- Fat depot-specific differences of macrophage infiltration and cellular senescence in obese bovine adipose tissues
- Source of chronic inflammation in aging
- Aging impairs beige adipocyte differentiation of mesenchymal stem cells via the reduced expression of Sirtuin 1
- Maternal high calorie diet induces mitochondrial dysfunction and senescence phenotype in subcutaneous fat of newborn mice
- Reduction of premature aging markers after gastric bypass surgery in morbidly obese patients
- Age-and tissue-specific expression of senescence biomarkers in mice
- Senolytics improve physical function and increase lifespan in old age
- Silencing of the small GTPase DIRAS3 induces cellular senescence in human white adipose stromal/progenitor cells
- ANGPTL2―A New Causal Player in Accelerating Heart Disease Development in the Aging―
- Melatonin prevents senescence of canine adipose-derived mesenchymal stem cells through activating NRF2 and inhibiting ER stress
- Cellular senescence: a translational perspective
- Rejuvenating senolytics
- Regulation of lipogenesis in human adipose tissue: Effect of metabolic stress, dietary intervention and aging.
- Cellular senescence in osteoarthritis pathology
- Metabolic memory of dietary restriction ameliorates DNA damage and adipocyte size in mouse visceral adipose tissue
- Aging of Brown and Beige/Brite adipose tissue
- Impact of senescence‐associated secretory phenotype and its potential as a therapeutic target for senescence‐associated diseases
- Cellular Senescence: At the Nexus of Mechanisms of Age-and Obesity-Related Metabolic Dysfunction
- The Progressive Low Chronic Inflammation On Oral Tissues In Elderly
- High Circulating Levels of ANGPTL2: Beyond a Clinical Marker of Systemic Inflammation
- Basic research: killing the old: cell senescence in atherosclerosis
- Cellular senescence: implications for metabolic disease
- Melatonin regulates PARP 1 to control the senescence‐associated secretory phenotype (SASP) in human fetal lung fibroblast cells
- Examination of the Inhibitory Protein P21 in Omento Fat as an Indication of Adipocyte Proliferation
- Augmentation of Dermal Wound Healing by adipose tissue-Derived Stromal Cells (ASC)
- Cell-free therapy with the secretome of adipose tissue-derived stem cells in rats’ frozen-thawed ovarian grafts
- The Complexity of adipose tissue
- Targeting cellular senescence prevents age-related bone loss in mice
- Targeting our aging cells to treat metabolic disease
- Different response to hypoxia of adipose-derived multipotent cells from obese subjects with and without metabolic syndrome
- Mitochondria in cell senescence: is mitophagy the weakest link?
- Diabetes and Adipocyte Dysfunction
- Nonalcoholic fatty liver disease promotes hepatocellular carcinoma through direct and indirect effects on hepatocytes
- Short-term sustained hyperglycaemia fosters an archetypal senescence-associated secretory phenotype in endothelial cells and macrophages
- Senescence and aging: Causes, consequences, and therapeutic avenues
- A summary of the Proceedings of the Thirteenth International Symposium on the Neurobiology and Neuroendocrinology of Aging, Bregenz, Austria July 17–22, 2016
- Killing the old: cell senescence in atherosclerosis
- New agents that target senescent cells: the flavone, fisetin, and the BCL-XL inhibitors, A1331852 and A1155463
- Parallels Between Skeletal Muscle and Bone Aging
- Aging, obesity, and inflammatory age-related diseases
- Molecular pathology endpoints useful for aging studies
- Cellular senescence in postmitotic cells: beyond growth arrest
- Senescent cells: an emerging target for diseases of ageing
- Prevention of senescence in vasculature through quiescence
- Resveratrol reduces senescence-associated secretory phenotype by SIRT1/NF-κB pathway in gut of the annual fish Nothobranchius guentheri
- Inflammageing and metaflammation: the yin and yang of type 2 diabetes
- Chronic inflammation and sarcopenia: A regenerative cell therapy perspective
- Ageing: from inflammation to cancer
- Senotherapy: growing old and staying young?
- Down-regulation of guanylate binding protein 1 causes mitochondrial dysfunction and cellular senescence in macrophages
- Cellular senescence: Molecular mechanisms and pathogenicity
- Anti-inflammatory effect of Chang-An-Shuan on TNBS-induced experimental colitis in rats
- Senescent B cells in aging and age-related diseases: their role in the regulation of antibody responses
- The fountain of youth by targeting senescent cells?
- HIV-associated cellular senescence: a contributor to accelerated aging
- Inflammageing: chronic inflammation in ageing, cardiovascular disease, and frailty
- Activated tissue-resident mesenchymal stromal cells regulate natural killer cell immune and tissue-regenerative function
- Immunosenescence induced by plasma from individuals with obesity caused cell signaling dysfunction and inflammation
- Circadian Disruption, Sleep Loss, and Low-Grade Inflammation
- Histone MacroH2A1: a chromatin point of intersection between fasting, senescence and cellular regeneration
- PPARα regulates tumor cell proliferation and senescence via a novel target gene carnitine palmitoyltransferase 1C
- p16 (Ink4a) and senescence-associated β-galactosidase can be induced in macrophages as part of a reversible response to physiological stimuli
- Novel Role of Blackberries in Senescence and Atherosclerosis in ApoE-/-Mice
- The Role of Na/K-ATPase Signaling in Oxidative Stress Related to Aging: Implications in Obesity and Cardiovascular Disease
- Cellular senescence in renal ageing and disease
- Quantitative analysis of cellular senescence in culture and in vivo
- Ketone bodies mimic the life span extending properties of caloric restriction
- Rapamycin inhibits the secretory phenotype of senescent cells by a Nrf2‐independent mechanism
- Gut microbiota and mTOR signaling: insight on a new pathophysiological interaction
- Gut microbiota, fatty liver disease, and hepatocellular carcinoma
- Increase in tumor suppressor Arf compensates gene dysregulation in in vitro aged adipocytes
- Inhibiting cellular senescence: a new therapeutic paradigm for age-related osteoporosis
- The Na/K-ATPase oxidant amplification loop regulates aging
- Role of lncRNAs in aging and age‐related diseases
- TNFα-senescence initiates a STAT-dependent positive feedback loop, leading to a sustained interferon signature, DNA damage, and cytokine secretion
- Gut microbiota-mediated inflammation in obesity: a link with gastrointestinal cancer
- The impact of senescence-associated T cells on immunosenescence and age-related disorders
- Study on the therapeutic effects of salicylazosulfapyridine on ulcerative colitis in rats
- Emerging metabolic risk factors in hepatocellular carcinoma and their influence on the liver microenvironment
- Low-grade inflammation in the relationship between sleep disruption, dysfunctional adiposity, and cognitive decline in aging
- Musculoskeletal senescence: a moving target ready to be eliminated
- Inflammatory response in the CNS: friend or foe?
- Inflammation-accelerated senescence and the cardiovascular system: mechanisms and perspectives
- Biphasic modeling of mitochondrial metabolism dysregulation during aging
- Myeloid-derived suppressor cells (MDSC): an important partner in cellular/tissue senescence
- Mitochondrial peptides modulate mitochondrial function during cellular senescence
- Senescence of mesenchymal stem cells
- Sirtuins, a promising target in slowing down the ageing process
- Endothelin receptor type b blocker attenuates severity of osteoarthritis by clearance of senescent cells
- The Rbm38-p63 feedback loop is critical for tumor suppression and longevity
- Identification of senescent cell surface targetable protein DPP4
- Caloric Restriction, Sirtuins, and Ageing
- 5-methoxytryptophan protects MSCs from stress induced premature senescence by upregulating FoxO3a and mTOR
- SCAMP4 enhances the senescent cell secretome
- Age-related changes in glucose metabolism, hyperglycemia, and cardiovascular risk
- Investigating the Role of NRIP1 in Skin Aging: Depletion of NRIP1 Delays Senescence, Reduces Inflammation and Enhances Autophagy in Adipocytes
- The role of cellular senescence in aging through the prism of Koch-like criteria
- Heat-induced extracellular HSP72 release is blunted in elderly diabetic people compared with healthy middle-aged and older adults, but it is partially restored by …
- Drosophila as a Model to Study the Link between Metabolism and Cancer
- Oxidative stress-mediated senescence in mesenchymal progenitor cells causes the loss of their fibro/adipogenic potential and abrogates myoblast fusion
- Immune Senescence and Inflammaging in Neurological Diseases
- Inflammaging and human longevity in the omics era
- Role of sphingolipids in senescence: implication in aging and age-related diseases
- Mitochondrial activity and dynamics changes regarding metabolism in ageing and obesity
- Premature physiologic aging as a paradigm for understanding increased risk of adverse health across the lifespan of survivors of childhood cancer
- The molecular intersection between senescence and major depression in the elderly
- Senescent cells: a new Achilles’ heel to exploit for cancer medicine?
- From cellular senescence to age-associated diseases: miRNAs as tools and targets for healthy ageing
- Attenuation of inflammation and cartilage degradation by sulfasalazine-containing hyaluronic acid on osteoarthritis rat model
- Ripk3 regulates cardiac microvascular reperfusion injury: the role of IP3R-dependent calcium overload, XO-mediated oxidative stress and F-action/filopodia-based …
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- NAD+ Metabolism in Aging and Cancer
- Cellular Stress and General Pathological Processes
- A prospect of cell immortalization combined with matrix microenvironmental optimization strategy for tissue engineering and regeneration
- The expression of P16 and S100 associated with elastin degradation and fibrosis of the Ligamentum Flavum hypertrophy
- Risk Factors for Frailty and Cardiovascular Diseases: Are They the Same?
- MicroRNAs in the Functional Defects of Skin Aging
- Aging, Melatonin, and the Pro-and Anti-Inflammatory Networks
- Huang-Lian-Jie-Du decoction ameliorates acute ulcerative colitis in mice via regulating NF-κB and Nrf2 signaling pathways and enhancing intestinal barrier function
- Cellular senescence in cultured human brainstem astrocytes: Effect of oxidative stress
- A murine aging cell atlas reveals cell identity and tissue-specific trajectories of aging
- Exosomal long noncoding RNAs in aging and age‐related diseases
- Cellular senescence in the lung across the age spectrum
- Modulation of Human Neutrophil Peptides on P. aeruginosa Killing, Epithelial Cell Inflammation and Mesenchymal Stromal Cell Secretome Profiles
- Stabilizing heterochromatin by DGCR8 alleviates senescence and osteoarthritis
- Alpha-1 Antitrypsin Deficiency and Accelerated Aging: A New Model for an Old Disease?
- ERR agonism reverses mitochondrial dysfunction and inflammation in aging
- Senescent hepatocytes in decompensated liver show reduced UPRMT and its key player, CLPP, attenuates senescence in vitro
- Thrombin Induces Angiotensin II-Mediated Senescence in Atrial Endothelial Cells: Impact on Pro-Remodeling Patterns
- Preventive role of Resveratrol against inflammatory cytokines and related diseases
- Towards a unified mechanistic theory of aging
- Iguratimod: a valuable remedy from the Asia Pacific region for ameliorating autoimmune diseases and protecting bone physiology
- Autophagy and Immune Tolerance
- Investigating the role of microRNAs in the hypoxic response in prostate cancer
- Clinical Inference of Serum and Bone Sclerostin Levels in Patients with End-Stage Kidney Disease
- Healthy aging: A bibliometric analysis of the literature
- Danger signals and inflammaging in osteoarthritis
- Length‐independent telomere damage drives post‐mitotic cardiomyocyte senescence
- Orexins as novel therapeutic targets in inflammatory and neurodegenerative diseases
- Skin Health from the Inside Out
- SFRR-E 2019 ANNUAL MEETING “REDOX HOMEOSTASIS: FROM SIGNALING TO DAMAGE”
- Oleuropein, a Bioactive Compound from Olea europaea L., as a Potential Preventive and Therapeutic Agent in Non-Communicable Diseases
- Interleukin-1 and related cytokines in the regulation of inflammation and immunity
- Plenary Sessions
- Premature aging syndromes: From patients to mechanism
- Understanding the origin and diversity of macrophages to tailor their targeting in solid cancers
- Oxytocin Alleviates Cellular Senescence through Oxytocin Receptor‐Mediated ERK/Nrf2 Signalling
- Inflammation and cancer: triggers, mechanisms, and consequences
- Probiotic bacteria as modulators of cellular senescence: emerging concepts and opportunities
- Immunobiology of atherosclerosis: a complex net of interactions
- Beneficial effect of physical exercise on telomere length and aging, and genetics of aging-associated noncommunicable diseases
- Inflammaging and oxidative stress in human diseases: from molecular mechanisms to novel treatments
- Candesartan Neuroprotection in Rat Primary Neurons Negatively Correlates with Aging and Senescence: a Transcriptomic Analysis
- Methylglyoxal Acts as a Tumor-Promoting Factor in Anaplastic Thyroid Cancer
- The potential role of necroptosis in inflammaging and aging
- Multidimensional informatic deconvolution defines gender-specific roles of hypothalamic GIT2 in aging trajectories
- Enhancement of epithelial cell autophagy induced by sinensetin alleviates epithelial barrier dysfunction in colitis
- Age-related inflammation triggers skeletal stem/progenitor cell dysfunction
- Quantitative proteomic analyses in blood: A window to human health and disease
- The bystander effect contributes to the accumulation of senescent cells in vivo.
- Inhibition of JAK-STAT Signaling with Baricitinib Reduces Inflammation and Improves Cellular Homeostasis in Progeria Cells
- Antioxidative nanomaterials and biomedical applications
- Health Benefits of Anti-aging Drugs
- Exercise and dietary interventions in a rat model of metabolic knee osteoarthritis
- Tissue Engineering and Regenerative Medicine Therapies for Cell Senescence in Bone and Cartilage
- Placental Ageing in Adverse Pregnancy Outcomes: Telomere Shortening, Cell Senescence, and Mitochondrial Dysfunction
- Regulatory mechanisms and clinical manifestations of musculoskeletal aging
- Sex Steroids, Cognate Receptors, and Aging
- Epigenetic changes during aging and their reprogramming potential
- NAD+ therapy in age-related degenerative disorders: A benefit/risk analysis
- Premature cell senescence in human skin: dual face in chronic acquired pigmentary disorders
- 140-3D Hydrogels and Bioinks for Realistic In Vitro Modelling and Bioprinting
- Impact of aging on bone, marrow and their interactions
- FRI0531 THE ARTICULAR PROTECTION EFFECT OF ISORHAMNETIN IN THE RATS OF MONOSODIUM IODOACETATE-INDUCED OSTEOARTHRITIS
- Benefits of tree nuts consumption on aging and age-related diseases: mechanisms of actions
- Regulation of Wound Healing by the NRF2 Transcription Factor—More Than Cytoprotection
- Enhancement of therapeutic efficacy by immunomodulation in human mesenchymal stem cells
- PAK4 signaling in development and cancer
- Transposable Elements, Inflammation and Neurological Disease
- Drugs that target aging: how do we discover them?
- Extracellular matrix roles in cardiorenal fibrosis: Potential therapeutic targets for CVD and CKD in the elderly
- Murine models of accelerated aging and musculoskeletal disease
- Identification of differentially expressed transcription factors and dissecting the role of DREAM complex associated components in cellular senescence
- Inflammation and Liver Cancer: Molecular Mechanisms and Therapeutic Targets
- Senolytic therapy alleviates Aβ-associated oligodendrocyte progenitor cell senescence and cognitive deficits in an Alzheimer’s disease model
- Acquired Immune Response to Infection
- MHY2233 Attenuates Replicative Cellular Senescence in Human Endothelial Progenitor Cells via SIRT1 Signaling
- Methods to Quantify the NF-κB Pathway During Senescence
- Somatic mutations in healthy cells and age-associated diseases
- HER2 recruits AKT1 to disrupt STING signalling and suppress antiviral defence and antitumour immunity
- Investigating the immune system in chrONIC kidney disease-the SONIC study
- JOINT MEETING AGI–SIMAG
- Rejuvenation: Turning back the clock of aging kidney
- Characterisation of an in vitro aged cell culture model
- L1CAM and its role in cellular senescence
- The role of the cell-matrix interface in aging and its interaction with the renin-angiotensin system in the aged vasculature
- Time for the systems-level integration of aging: Resilience enhancing strategies to prevent Alzheimer’s disease
- Epigenetics and Pharmacoepigenetics of Age-Related Neurodegenerative Disorders
- Molecular basis of senescence transmitting in the population of human endometrial stromal cells
- Shared and distinct mechanisms of fibrosis
- Skeletal Muscle Stem Cells
- Are There Reliable Biomarkers for Immunosenescence and Inflammaging?
- Epidermal growth factor (EGF) intralesional infiltrations: from the bench to the diabetic ulcers cells
- Senescence surveillance: the interplay between the immune system and senescent cells
- Exosomes as Emerging Pro-Tumorigenic Mediators of the Senescence-Associated Secretory Phenotype
- Age-Associated Changes in the Immune System and Blood–Brain Barrier Functions
- Recent advances in understanding the phenotypes of osteoarthritis
- Inducing Age Related Changes in Microglia as a Model for Neurodegenerative Disease
- Convallatoxin protects against dextran sulfate sodium-induced experimental colitis in mice by inhibiting NF-κB signaling through activation of PPARγ
- Innate immune cell crosstalk induces melanoma cell senescence
- Characterization and Analysis of Neural Progenitor Cells from Primary Progressive Multiple Sclerosis Patients
- Targeting Cell Senescence for the Treatment of Age-Related Bone Loss
- Ell3 functions as a critical decision maker at the crossroad between stem cell senescence and apoptosis
- The role of exosomes in regenerative medicine
- Mitochondrial dysfunction and cell senescence: deciphering a complex relationship
- The Effects of IL-1β on Astrocytes are Conveyed by Extracellular Vesicles and Influenced by Age
- The role of senescence in cancer development
- 41th Volume Index
- The proteome of ulcerative colitis-Functional analyses of the active disease and the remission state in comparison with healthy controls
- Allostatic load and ageing: linking the microbiome and nutrition with age-related health
- Rosiglitazone ameliorates senescence and promotes apoptosis in ovarian cancer induced by olaparib
- Novel insights of elevated systemic levels of bisphenol-A (BPA) linked to poor glycemic control, accelerated cellular senescence and insulin resistance in patients with …
- Methods for CPP Functionalization
- Probing the impact of the maternal environment on foetal development: Can high-resolution telomere analysis predict prenatal adversity?
- Bone marrow stromal cells from β-thalassemia patients have impaired hematopoietic supportive capacity
- Recurrent circadian fasting (RCF) improves blood pressure, biomarkers of cardiometabolic risk and regulates inflammation in men
- Noncoding RNAs: Bridging Regulation of Circadian Rhythms and Inflammation
- Accelerated cardiomyocyte senescence contributes to late-onset doxorubicin-induced cardiotoxicity.
- SEXUAL ABUSE: HOW CAN WE KNOW?
- Metabolic phenotyping of the human microbiome
- Reduced RNA turnover as a driver of cellular senescence
- The role of metabolism in the anti-tumor cytotoxicity of natural killer cells
- Microncronucleus index in epithelial exfoliated cells of urothelium and buccal mucosa, and peripheral blood lymphocytes of patients with papillary urothelial …
- Transient non-integrative nuclear reprogramming promotes multifaceted reversal of aging in human cells
- Senolytic activity of small molecular polyphenols from olive restores chondrocyte redifferentiation and cartilage regeneration in osteoarthritis
- PTEN loss regulates alveolar epithelial cell senescence in pulmonary fibrosis depending on Akt activation
- Mitophagy, Mitochondrial Dynamics, and Homeostasis in Cardiovascular Aging
- TGF-β in Hepatic Stellate Cell Activation and Liver Fibrogenesis—Updated 2019
- Know your enemy: Genetics, aging, exposomic and inflammation in the war against triple negative breast cancer
- NAD+ in brain aging and neurodegenerative disorders
- Prelamin A mediates myocardial inflammation in dilated and HIV-associated cardiomyopathies
- miR-140 Attenuates the Progression of Early-Stage Osteoarthritis by Retarding Chondrocyte Senescence
- The dark side of fibroblasts: cancer-associated fibroblasts as mediators of immunosuppression in the tumor microenvironment
- The role of signaling pathways of inflammation and oxidative stress in development of senescence and aging phenotypes in cardiovascular disease
- Emerging targets of disease-modifying therapy for systemic sclerosis
- Identification and characterization of inter-species aging-related transcriptomic regulators
- Mouse Models of Accelerated Cellular Senescence
- Cranberries–potential benefits in patients with chronic kidney disease
- Mitochondrial Homeostasis and Cellular Senescence
- Amelioration of age‐related brain function decline by Bruton’s tyrosine kinase inhibition
- NLRP3 inflammasome suppression improves longevity and prevents cardiac aging in male mice
- Paeonol prevents IL-1β-induced inflammatory response and degradation of type II collagen in human primary chondrocytes
- Scarless wound healing: From development to senescence
- β cell responses to inflammation
- The modular proteome and its significance
- Activated Fibroblast Program Orchestrates Tumor Initiation and Progression; Molecular Mechanisms and the Associated Therapeutic Strategies
- Ferroptosis, a new form of cell death: opportunities and challenges in cancer
- Senescence-associated metabolomic phenotype in primary and iPSC-derived mesenchymal stromal cells
- Leukocyte Telomere Length in Patients with Radiographic Knee Osteoarthritis
- Concepts in Inflammatory Bowel Disease Management
- Protein Signatures of Centenarians and Their Offspring Suggest Centenarians Age Slower than Other Humans
- Tumor microenvironment: Interactions and therapy
- The TGF-β1/p53/PAI-1 Signaling Axis in Vascular Senescence: Role of Caveolin-1
- Stromal cell-derived factor-1 (CXCL12) and its role in bone and muscle biology
- Measuring biological aging in humans: A quest
- Amelioration of Ductular Reaction by Stem Cell Derived Extracellular Vesicles in MDR2 Knockout Mice via Lethal‐7 microRNA
- Activation of melatonin receptor 2 but not melatonin receptor 1 mediates melatonin‐conferred cardioprotection against myocardial ischemia/reperfusion injury
- Proteomic Markers for Depression
- Induction of Fibroblast Senescence During Mouse Corneal Wound Healing
- Regulation of Thirst and Vasopressin Release
- Hyper-osmolarity environment-induced oxidative stress injury promotes nucleus pulposus cell senescence in vitro
- Novel drug targets in idiopathic pulmonary fibrosis
- Sleep, stress, and immunity
- Meeting report: Metastasis Research Society (MRS) 17th Biennial conference and associated Young Investigator Satellite Meeting (YISM) on cancer metastasis
- Targeting pro-senescence mitogen activated protein kinase (Mapk) enzymes with bioactive natural compounds
- Coordination of immune-stroma crosstalk by IL-6 family cytokines
- Long non-coding RNA CDKN2B-AS1 reduces inflammatory response and promotes cholesterol efflux in atherosclerosis by inhibiting ADAM10 expression
- Proceedings of the 2018 Santa Fe Bone Symposium: Advances in the Management of Osteoporosis
- The telomere world and aging: Analytical challenges and future perspectives
- The cross-talk between sphingolipids and insulin-like growth factor signaling: significance for aging and neurodegeneration
- Young Hematopoietic Stem Cells Ameliorate Age-Associated Phenotypes and Extend Lifespan in Mice
- MicroRNA networks modulate oxidative stress in cancer
- The RXFP3 receptor is functionally associated with cellular responses to oxidative stress and DNA damage
- Crosstalk between HGF and TGF-ß signaling pathways in adult liver progenitor cells and hepatocellular carcinoma cells
- The Evolving Role of CD8+ CD28− Immunosenescent T Cells in Cancer Immunology
- Astrocytes autophagy in aging and neurodegenerative disorders
- Stem cells: a path towards improved epilepsy therapies
- Novel function of PiT1/SLC20A1 in LPS-related inflammation and wound healing
- Biomarkers of Aging (With a Clinical Potential in Oncology)
- Mitochondrial oxidative stress-induced transcript variants of ATF3 mediate lipotoxic brain microvascular injury
- MOTOR BEHAVIOR
- Mediterranean Diet (Prong-4)
- Resveratrol: A New Potential Therapeutic Agent for Melanoma?
- EFFECT OF ADVANCED MATERNAL AGE ON PREGNANCY
