HSP90
January 6, 2020PREMATURE SENESCENCE
January 7, 2020
- A branching process model of telomere shortening
- A continuous correlation between oxidative stress and telomere shortening in fibroblasts
- A Critical Role for Pin2/TRF1 in ATM-dependent Regulation
- INHIBITION OF Pin2/TRF1 FUNCTION COMPLEMENTS telomere shortening, RADIOSENSITIVITY, AND THE G2/M CHECKPOINT DEFECT OF ATAXIA-TELANGIECTASIA CELLS
- A G-quadruplex-interactive agent, telomestatin (SOT-095), induces telomere shortening with apoptosis and enhances chemosensitivity in acute myeloid leukemia
- A Home Use Study in Healthy Volunteers to Assess Effectiveness of a Dietary Supplement to Halt the Shortening of telomere Length as Demonstrated by the “ …
- A kinetic model of telomere shortening in infants and adults
- A protein array screen for Kaposi’s sarcoma-associated herpesvirus LANA interactors links LANA to TIP60, PP2A activity, and telomere shortening
- A randomized-controlled clinical study of Telos95®, a novel antioxidative dietary supplement, on the shortening of telomere length in healthy volunteers
- A stochastic model of cell replicative senescence based on telomere shortening, oxidative stress, and somatic mutations in nuclear and mitochondrial DNA
- A tel2 Mutation That Destabilizes the Tel2-Tti1-Tti2 Complex Eliminates Rad3ATR Kinase Signaling in the DNA Replication Checkpoint and Leads to telomere shortening in Fission Yeast
- A TIN2 dyskeratosis congenita mutation causes telomerase-independent telomere shortening in mice
- A15812 Angiotensin Converting Enzyme Inhibitors Epigenetically Atenuate telomere shortening
- A7. 9 Does telomere shortening in Women with Rheumatoid Arthritis Predict X Chromosome Inactivation Bias?
- AB181. telomere shortening is associated with genetic anticipation in Chinese Von Hippel-Lindau disease families
- Abnormal telomere shortening in leucocytes of children with Shwachman–Diamond syndrome
- Abnormal telomere shortening of peripheral blood mononuclear cells and granulocytes in patients with chronic idiopathic neutropenia
- Abrogation of miR-195 Improves Function in Aged Heart by Preventing telomere shortening and Mitochondrial Dysfunction
- Abrupt telomere shortening in cell aging and cancer
- Abrupt telomere shortening in normal human fibroblasts
- Absence of telomere shortening and oxidative DNA damage in the young adult offspring of women with pre-gestational type 1 diabetes
- Abstract A63: Rsf-1, a chromatin remodeling protein, interacts with shelterin protein hRap1 and induces telomere shortening
- Abstract# 3036: telomere length shortening in individuals with sporadic compared with familial breast cancer
- Abstract# 3482: telomere shortening in human tumor cells in vitro and in vivo following treatment with telomerase inhibitor, GRN163L
- Abstract# 4505: Peripheral telomere shortening is most closely associated with young age of onset for pancreatic cancer
- Abstract# 5139: The inflammatory cytokine TNF-\# 945; induces rapid, reversible telomere shortening in breast cancer cell lines
- Accelerated aging as evidenced by increased telomere shortening and mitochondrial DNA depletion in patients with type 2 diabetes
- Accelerated telomere length shortening in granulocytes: a diagnostic marker for myeloproliferative diseases
- Accelerated telomere shortening and replicative senescence in human fibroblasts overexpressing mutant and wild-type lamin A
- Accelerated telomere shortening and senescence in human pancreatic islet cells stimulated to divide in vitro
- Accelerated telomere shortening and telomerase activation in Fanconi’s anaemia
- Accelerated telomere shortening and telomere abnormalities in radiosensitive cell lines
- Accelerated telomere shortening following allogeneic transplantation is independent of the cell source and occurs within the first year post transplant
- Accelerated telomere shortening in acromegaly; IGF-I induces telomere shortening and cellular senescence
- Accelerated telomere shortening in ataxia telangiectasia
- Accelerated telomere shortening in bonemarrow recipients
- Accelerated telomere shortening in CD8+ T-lymphocytes From Patients With Coronary Heart Disease Links Cytomegalovirus-Induced T Cell Response and …
- Accelerated telomere shortening in Fanconi anemia fibroblasts–a longitudinal study
- Accelerated telomere shortening in fibroblasts after extended periods of confluency
- Accelerated telomere shortening in peripheral blood lymphocytes after occupational polychlorinated biphenyls exposure
- Accelerated telomere shortening in Response to Air Pollution from Traffic Emissions.
- Accelerated telomere shortening in response to life stress
- Accelerated telomere shortening in rheumatic diseases: cause or consequence?
- Accelerated telomere shortening in the human inactive X chromosome
- Accelerated telomere shortening in young recipients of allogeneic bone-marrow transplants
- Accelerated telomere shortening in β-thalassemia/HbE patients
- Accelerated telomere shortening precedes development of therapy-related myelodysplasia or acute myelogenous leukemia after autologous transplantation …
- Accelerated telomere shortening: Tracking the lasting impact of early institutional care at the cellular level
- Accumulation of single-strand breaks is the major cause of telomere shortening in human fibroblasts
- Advanced telomere shortening in respiratory chain disorders
- Age estimation in dental pulp DNA based on human telomere shortening
- Age-associated telomere shortening in mouse oocytes
- Age-associated telomere shortening in Thoroughbred horses
- Age-dependent telomere shortening is slowed down by enrichment of intracellular vitamin C via suppression of oxidative stress
- Age‐dependent telomere‐shortening is repressed by phosphorylated α‐tocopherol together with cellular longevity and intracellular oxidative‐stress reduction in …
- Age-independent telomere shortening and ion-channel defects in SCD
- Ageing and telomeres: a study into organ‐and gender‐specific telomere shortening
- Age-related telomere shortening occurs in lens epithelium from old rats and is slowed by caloric restriction
- Age-related telomere uncapping is associated with cellular senescence and inflammation independent of telomere shortening in human arteries
- Age-Related telomere Uncapping Occurs Independent of telomere shortening in Mouse Endothelial Cells
- Aging-related telomere shortening and cognitive decline in the Betula study: No evidence of coupled changes
- Alpha-tocopherol modulates hydrogen peroxide-induced DNA damage and telomere shortening of human skin fibroblasts derived from differently aged individuals
- Amplification of the human epidermal growth factor receptor 2 gene in differentiated thyroid cancer correlates with telomere shortening
- An association between telomere shortening and disease evolution patterns in MDS
- An investigation on mitochondrial DNA deletions and telomere shortening during multiple passages of adult stem cells
- An Isogenic Trisomic–Disomic Model System Using Cells from People with Mosaic Down Syndrome Unmasks Trisomy 21 Associated Increases in Age-Related Chromosomal Instability, Senescence Associated Distension of Satellites, and telomere shortening
- Analysis of the telomere shortening in the cloned caprine cultured cell line, CPF-1, derived from placenta of Shiba goat (Capra hircus)
- Ancestral telomere shortening: A countdown that will increase mean life span?
- Angiotensin II type 1 receptor gene polymorphism and telomere shortening in essential hypertension
- Antisense oligonucleotide-mediated inhibition of hTERT, but not hTERC, induces rapid cell growth decline and apoptosis in the absence of telomere shortening in human prostate cancer cells
- Artemisinin mimics calorie restriction to initiate antioxidative responses and compromise telomere shortening
- Artemisinin mimics calorie restriction to trigger mitochondrial biogenesis and compromise telomere shortening in mice
- Artificial light at night does not affect telomere shortening in a developing free-living songbird: A field experiment: Artificial light at night and telomere dynamics
- Asp-Ala-His-Lys (DAHK) inhibits copper-induced oxidative DNA double strand breaks and telomere shortening
- Association between antidiabetic agents use and leukocyte telomere shortening rates in patients with type 2 diabetes
- Association between leukocyte telomere shortening and exposure to traffic pollution: a cross-sectional study on traffic officers and indoor office workers
- Association between oxidative DNA damage and telomere shortening in circulating endothelial progenitor cells obtained from metabolic syndrome patients with …
- Association between telomere shortening and ageing during occupational exposure
- Association of Immune Abnormalities with telomere shortening in
- Association of telomere shortening in myocardium with heart weight gain and cause of death
- Association of telomere shortening with impaired glucose tolerance and diabetic macroangiopathy
- Asynchronous Shortening of telomere Length and Cardiovascular Outcomes
- ATF7 mediates TNF-α–induced telomere shortening
- Authors’ Response Correlation between baseline telomere length and shortening over time—spurious or true?
- Biological age instead of chronologic age as prognostic factor in IPF: clinical implications of telomere shortening
- Biomarkers of oxidative stress: methods and measures of oxidative DNA damage (COMET assay) and telomere shortening
- BJ fibroblasts display high antioxidant capacity and slow telomere shortening independent of hTERT transfection
- Blood cell telomere lengths and shortening rates of chimpanzee and human females
- Bone morphogenetic protein-7 induces telomerase inhibition, telomere shortening, breast cancer cell senescence, and death via Smad3.
- C21 MECHANISMS THAT LINK AGING WITH LUNG DISEASE: THE CUTTING EDGE: Acrolein Induces P53-Mediated Cellular Senescence Accompanied By Enhanced Werner’s Syndrome Protein Degradation And telomere shortening
- Can leukocyte telomere shortening be a possible biomarker to track Huntington’s disease progression?
- Can telomere shortening be the main indicator of non-viable fetus elimination?
- Can telomere shortening explain sigmoidal growth curves?
- Can telomere shortening in human peripheral blood leukocytes serve as a disease biomarker of Friedreich’s ataxia?
- Candidate drug BIBR1532 induces telomere shortening and growth inhibition in lymphoid cell lines
- Cardiomyocyte-Specific telomere shortening is a Distinct Signature of Heart Failure in Human
- Cardiomyocyte‐Specific telomere shortening is a Distinct Signature of Heart Failure in Humans
- Casein Kinase II (csnk2a2) is Associated With Leucocyte telomere shortening and Increased Cardiovascular Disease Risk in Diabetes
- CD 57 identifies T cells with functional senescence before terminal differentiation and relative telomere shortening in patients with activated PI 3 kinase delta …
- Celiac disease autoimmunity is associated with leukocyte telomere shortening in older adults: the US National Health and Nutrition Examination Survey
- Cell contact accelerates replicative senescence of human mesenchymal stem cells independent of telomere shortening and p53 activation: roles of Ras and oxidative …
- CELL CYCLE ARREST AND ACCELERATED telomere shortening IN NON-ALCOHOLIC FATTY LIVER DISEASE (NAFLD)
- Cell cycle-dependent and-independent telomere shortening accompanies murine brain aging
- Cell senescence and telomere shortening induced by a new series of specific G-quadruplex DNA ligands
- Cell senescence in rat kidneys in vivo increases with growth and age despite lack of telomere shortening
- Cellular consequences of telomere shortening in histologically normal breast tissues
- Cellular senescence mechanisms independent of telomere shortening and telomerase: other barriers to cell immortalization and carcinogenesis
- CEREBRAL VASCULAR HEALTH AND ACCELERATED LEUKOCYTE telomere shortening IN TYPE II DIABETES.
- Childhood maltreatment and telomere shortening: preliminary support for an effect of early stress on cellular aging
- Chlorella vulgaris modulates hydrogen peroxide-induced DNA damage and telomere shortening of human fibroblasts derived from different aged individuals
- Chromosomal instability and telomere shortening in long-term culture of hematopoietic stem cells: insights from a cell culture model of RPS14 haploinsufficiency
- Chromosomal instability in Barrett’s esophagus is related to telomere shortening
- Chromosomal instability in ulcerative colitis is related to telomere shortening
- Chromosomal instability, telomere shortening, and inactivation of p21WAF1/CIP1 in dysplastic nodules of hepatitis B virus-associated multistep …
- Chromosomal telomere shortening of kidney cells in IgA nephropathy by the measurement of DNA in urinary sediment.
- Chronic Oxidative Stress Leads To Accelerated telomere shortening In Children With Alpha-1 Antitrypsin Deficiency
- Chronic psychosocial and financial burden accelerates 5-year telomere shortening: findings from the Coronary Artery Risk Development in Young Adults Study
- Clinical impact of telomere shortening in normal and leukemia cells in chronic lymphocytic leukemia
- Clinical predictive factors and prognostic implications of telomere shortening in sporadic and familial idiopathic pulmonary fibrosis
- Clonal haemopoiesis may occur after conventional chemotherapy and is associated with accelerated telomere shortening and defects in the NQO1 pathway; possible …
- Cocaine use may induce telomere shortening in individuals with HIV infection
- Colonocyte telomere shortening is greater with dietary red meat than white meat and is attenuated by resistant starch
- Comments on “Is telomere shortening reversible? A clue from NASA’s twins mission”
- Comparison of Southern blotting and Real-time PCR in measuring telomere shortening
- Concomitant telomere shortening, acquisition of multiple chromosomal aberrations and in vitro resistance to apoptosis in a single case of progressive CLL
- Consequences of acute oxidative stress in Leishmania amazonensis: From telomere shortening to the selection of the fittest parasites
- Consequences of telomere shortening at an active VSG expression site in telomerase-deficient Trypanosoma brucei
- Consequences of telomere shortening during lifespan
- Constitutive OGG1 variant together with BRCA mutations display accelerated telomere shortening
- Contact-independent suppressive activity of regulatory T cells is associated with telomerase inhibition, telomere shortening and target lymphocyte apoptosis
- Contrasting effects of telomere shortening on organ homeostasis, tumor suppression, and survival during chronic liver damage
- Convergence of adipocyte hypertrophy, telomere shortening and hypoadiponectinemia in obese subjects and in patients with type 2 diabetes
- Conversion of normal to malignant phenotype: telomere shortening, telomerase activation, and genomic instability during immortalization of human oral keratinocytes
- Correlates of telomere length shortening in peripheral leukocytes of HIV-infected individuals and association with leukoaraiosis
- Correlation of telomere length shortening with promoter methylation profile of p16/Rb and p53/p21 pathways in breast cancer
- Correlation of telomere length shortening with TP53 somatic mutations, polymorphisms and allelic loss in breast tumors and esophageal cancer
- Correlation telomere shortening in chronic lymphocytic leukemia cells with oxidative stress and dysregulation of shelterin proteins
- Correlative polymorphism of NAD (P) H: quinone oxidoreductase (NQO1) with telomere shortening in colorectal cancer.
- Cortisol increases DNA damage in lymphocytes in vitro, but is not associated with telomere shortening
- Cortisol is not associated with telomere shortening or chromosomal instability in human lymphocytes cultured under low and high folate conditions
- Critical telomere shortening regulated by the ataxia-telangiectasia gene acts as a DNA damage signal leading to activation of p53 protein and limited life-span …
- CTC1 increases the radioresistance of human melanoma cells by inhibiting telomere shortening and apoptosis
- Curcumin inhibits telomerase and induces telomere shortening and apoptosis in brain tumour cells
- Data Mining in the Research and Application of telomere shortening
- Decreased dyskerin levels as a mechanism of telomere shortening in X-linked dyskeratosis congenita
- Decreasing initial telomere length in humans intergenerationally understates age‐associated telomere shortening
- Deficiency in DNA mismatch repair increases the rate of telomere shortening in normal human cells
- Demonstration of potential link between helicobacter pylori related promoter CpG island methylation and telomere shortening in human gastric mucosa
- Deoxyribonucleic acid telomere length shortening can predict the incidence of non‐alcoholic fatty liver disease in patients with type 2 diabetes mellitus
- Deregulated telomere transcription causes replication-dependent telomere shortening and promotes cellular senescence
- Developing a Model for Stress-Associated telomere shortening: Effects of Stress-Related Mediators on Telomerase Activity
- Development of a new multiplex quantitative real‐time PCR assay for the detection of the mtDNA4977 deletion in coronary artery disease patients: A link with telomere shortening
- Diet Influences telomere shortening: Eating Your Way to the Fountain of Youth?
- Diet-Induced Leukocyte telomere shortening Correlates with Extent of Atherosclerosis
- Diet-induced leukocyte telomere shortening in a baboon model for early stage atherosclerosis
- Diet-related telomere shortening and chromosome stability
- Different effects of accelerated development and enhanced growth on oxidative stress and telomere shortening in amphibian larvae
- Different Phase of telomere shortening with Age in Peripheral Blood Mononuclear Cells
- Different rates of telomere shortening and telomerase activity reduction in CD8 T and CD16 NK lymphocytes with ageing
- Differential expression of non-shelterin genes associated with high telomerase levels and telomere shortening in plasma cell disorders
- Differential shortening rate of telomere length in the development of human fetus
- Differential telomere shortening in blood versus arteries in an animal model of type 2 diabetes
- Differential timing of oxidative DNA damage and telomere shortening in hepatitis C and B virus–related liver carcinogenesis
- Disease anticipation is associated with progressive telomere shortening in families with dyskeratosis congenita due to mutations in TERC
- Divergent patterns of telomere shortening in tropical compared to temperate stonechats
- DNA damage and telomere length shortening in the peripheral blood leukocytes of 20 years SM-exposed veterans
- DNA Damage and telomere shortening in Embryonic Stem Cells Induced by Cigarette Smoke.
- DNA damage response correlates with telomere shortening and telomeric proteins down regulation in the colorectal multistep process
- DNA demethylation leads to telomere shortening with accelerated aging process in human diploid fibroblasts
- DNA methylation of human telomerase reverse transcriptase associated with leukocyte telomere length shortening in hyperhomocysteinemia-type hypertension in …
- Does telomere shortening precede the onset of hypertension in spontaneously hypertensive mice?
- Downregulation of methyltransferase Dnmt2 results in condition‐dependent telomere shortening and senescence or apoptosis in mouse fibroblasts
- Down-regulation of telomerase activity and replication-independent telomere shortening induced by SH-7 in human leukemia HL-60 cells
- Dynamics of telomere shortening in neutrophils and T lymphocytes during ageing and the relationship to skewed X chromosome inactivation patterns
- Dyslipidemia and chronic inflammation markers are correlated with telomere length shortening in Cushing’s syndrome
- Dysregulation of shelterin factors coupled with telomere shortening in Philadelphia chromosome negative myeloproliferative neoplasms
- Early and late steps in telomere overhang processing in normal human cells: the position of the final RNA primer drives telomere shortening
- Early growth determines longevity in male rats and may be related to telomere shortening in the kidney
- Early Senescence and Leukocyte telomere shortening in SCHIZOPHRENIA: A Role for Cytomegalovirus Infection?
- Early telomere shortening and Genomic Instability in Tubo-Ovarian Preneoplastic Lesions
- Early telomere shortening and genomic instability in tubo-ovarian preneoplastic lesions—response
- Early-senescing human skin fibroblasts do not demonstrate accelerated telomere shortening
- Effect of D-gal on mouse fibroblast telomere shortening
- Effect of maternal protein restriction upon growth, longevity and telomere shortening
- Enhanced microglial pro‐inflammatory response to lipopolysaccharide correlates with brain infiltration and blood–brain barrier dysregulation in a mouse model of telomere shortening
- Enhanced telomere shortening in transformed lymphoblasts from patients with X linked dyskeratosis
- Epigallocatechin‐3‐gallate induces telomere shortening and clastogenic damage in glioblastoma cells
- Estimating age of humans based on telomere shortening
- Estimation of human age according to telomere shortening in peripheral blood leukocytes
- Estimation of human age according to telomere shortening in peripheral blood leukocytes of Tibetan
- Estrogen deficiency leads to telomerase inhibition, telomere shortening and reduced cell proliferation in the adrenal gland of mice
- Estrogen deficiency reversibly induces telomere shortening in mouse granulosa cells and ovarian aging in vivo
- EVALUATION OF DYNAMIC telomere LENGTH SHORTENING OF LYMPHOCYTES IN IMMUNOCOMPROMISED CHILDREN WITH CHRONIC DISEASES OF THE …
- Evaluation of the mechanism of nucleoplasmic bridge formation due to premature telomere shortening in agricultural workers exposed to mixed pesticides …
- Examining a scaled dynamical system of telomere shortening
- Excess Neurohormonal Activation-Induced Heart Failure Results in Significant but Non-Critical Cardiomyocyte telomere shortening, Which is Associated With …
- Excess of Yra1 RNA-Binding Factor Causes Transcription-Dependent Genome Instability, Replication Impairment and telomere shortening
- Exercise training increase antioxidant enzyme capacity and protect the shortening of telomere length
- Exome Sequencing Links Loss-of-Function and Missense Mutations in PARN and RTEL1 with Familial Pulmonary Fibrosis and telomere shortening
- Exome sequencing links mutations in PARN and RTEL1 with familial pulmonary fibrosis and telomere shortening
- Expression of miR-23a induces telomere shortening and is associated with poor clinical outcomes in patients with coronary artery disease
- Expression of mutant RPA in human cancer cells causes telomere shortening
- Expression of TRF1, TRF2, TIN2, TERT, KU70, and BRCA1 proteins is associated with telomere shortening and may contribute to multistage carcinogenesis of gastric …
- Extracellular superoxide dismutase is a major antioxidant in human fibroblasts and slows telomere shortening
- F19. telomere shortening IN YOUNG PEOPLE WITH FIRST EPISODE PSYCHOSIS: A 12-MONTH FOLLOW-UP STUDY
- Fetal growth restriction is associated with accelerated telomere shortening and increased expression of cell senescence markers in the placenta
- Flow cytometric detection of accelerated telomere shortening in myelodysplastic syndromes: correlations with aetiological and clinical–biological findings
- Forensic application of telomere shortening in age-at-death estimation
- Fragmentation and rapid shortening of telomere in HeLa cells in the early phase of hydroxyl radical-induced apoptosis
- From cellular senescence to Alzheimer’s disease: The role of telomere shortening
- From incomplete penetrance with normal telomere length to severe disease and telomere shortening in a family with monoallelic and biallelic PARN pathogenic …
- Functional haplotypes of the hTERT gene, leukocyte telomere length shortening, and the risk of peripheral arterial disease
- Fusing Aging Theories: telomere shortening Leads to Mitochondrial Dysfunction Fusing Aging Theories: telomere shortening Leads to Mitochondrial …
- Gemcitabine causes telomere shortening by stabilizing TRF2
- Gender specific profiles of human telomere shortening during aging
- Gene disruption of a G4-DNA-dependent nuclease in yeast leads to cellular senescence and telomere shortening
- Genetic anticipation is associated with telomere shortening in hereditary breast cancer
- Genetic heterogeneity of HER2 amplification and telomere shortening in papillary thyroid carcinoma
- Genomic imbalances in key ion channel genes and telomere shortening in sudden cardiac death victims
- Genotoxic risk of ethyl‐paraben could be related to telomere shortening
- Ginger (Zingiber officinale) Extract Promotes telomere shortening and Induces Cellular Senescence in A549 Lung Cancer Cells
- Ginger Extract Promotes telomere shortening and Cellular Senescence in A549 Lung Cancer Cells
- GP 12.03 telomere shortening and telomere-associated proteins in Duchenne muscular dystrophy
- Gradual telomere shortening and increasing chromosomal instability among PanIN grades and normal ductal epithelia with and without cancer in the …
- Growth arrest, apoptosis, and telomere shortening of Barrett’s-associated adenocarcinoma cells by a telomerase inhibitor
- Growth kinetics rather than stress accelerate telomere shortening in cultures of human diploid fibroblasts in oxidative stress‐induced premature senescence
- Growth kinetics rather than stress accelerate telomere shortening in cultures of human diploid fibroblasts in oxidative…
- Haploinsufficiency of Parp1 accelerates Brca1-associated centrosome amplification, telomere shortening, genetic instability, apoptosis, and embryonic …
- Helicobacter pylori-induced chronic inflammation causes telomere shortening of gastric mucosa by promoting PARP-1-mediated non-homologous end joining of DNA
- Hepatocellular telomere shortening correlates with chromosomal instability and the development of human hepatoma
- Hepatocyte telomere shortening and senescence are general markers of human liver cirrhosis
- Hepatocyte telomere shortening of primary HCC correlates with increasing aneuploidy of chromosome 8
- High lead exposure is associated with telomere length shortening in Chinese battery manufacturing plant workers
- High resolution telomere FISH analysis of testicular germ cell tumors reveals telomere anomalies specific to cancer subtypes and demonstrates telomere shortening as an early event in TGCT carcinogenesis
- Higher serum phenylalanine concentration is associated with more rapid telomere shortening in men
- Hostility and telomere shortening among US military veterans: Results from the National Health and Resilience in Veterans Study
- Hydroxyl radical‐induced apoptosis in human tumor cells is associated with telomere shortening but not telomerase inhibition and caspase activation
- Immortalization of human oral keratinocytes is associated with elevation of telomerase activity and shortening of telomere length.
- Immunosenescence and rheumatoid arthritis: does telomere shortening predict impending disease?
- Impact of telomere shortening on cell cycle progression and induction of senescence
- Impact of telomere shortening with Age in Stem Cell Therapy: New Strategies to Increase telomere Length
- Improved Methods for Analysis of Telomere-initiated Cellular Senescence and telomere shortening in Saccharomyces Cerevisiae
- In vitro proinflammatory gene expression predicts in vivo telomere shortening: A preliminary study
- In utero TNF‐α treatment induces telomere shortening in young adult mice in an ATF7‐dependent manner
- Increased expression of p21 in CD14+ human monocytes correlates with telomere shortening in ocular sarcoidosis patients
- Increased genomic alteration complexity and telomere shortening in B-CLL cells resistant to radiation-induced apoptosis
- Independent and Combined Effects of telomere shortening and mtDNA4977 Deletion on Long-term Outcomes of Patients with Coronary Artery Disease
- Induction of nitric oxide synthase-dependent telomere shortening after functional inhibition of Hsp90 in human tumor cells
- Induction of telomere shortening and cellular apoptosis by sodium meta-arsenite in human cancer cell lines
- Induction of telomere shortening and replicative senescence by cryopreservation
- Inflammatory response to acute mental stress is associated with altered cortisol reactivity and telomere shortening in patients with coronary artery disease
- Inhibition of 6A8 α-mannosidase gene expression resulted in telomere length shortening in nasopharyngeal carcinoma cell CNE-2L2
- Inhibition of human telomerase in immortal human cells leads to progressive telomere shortening and cell death
- Inhibition of microRNA-34a Protects against Aging and Progeria Associated Cardiac Dysfunction by Interfering with telomere shortening and DNA Damage …
- Inhibition of tankyrase 1 in human gastric cancer cells enhances telomere shortening by telomerase inhibitors
- INSULIN RESISTANCE DETERMINES telomere shortening IN PHAGOCYTIC CELLS FROM METABOLIC SYNDROME PATIENTS. INVOLVEMENT OF …
- Intramitotic and intraclonal variation in proliferative potential of human diploid cells: explained by telomere shortening
- Inula Viscosa Extracts Induces telomere shortening and Apoptosis in Cancer Cells and Overcome Drug Resistance
- Investigation of telomere shortening caused by dyskeratosis congenita-associated heterozygous TIN2 mutations
- Ionizing radiation-induced gene modulations, cytokine content changes and telomere shortening in mouse fetuses exhibiting forelimb defects
- iPSC modeling of severe aplastic anemia reveals impaired differentiation and telomere shortening in blood progenitors
- Irreversible cellular senescence induced by prolonged exposure to H2O2 involves DNA-damage-and-repair genes and telomere shortening
- Irreversible telomere shortening by 3′-azido-2′, 3′-dideoxythymidine (AZT) treatment
- Is telomere Length shortening a Predictive Biomarker for Cancer Risk in Ulcerative Colitis?
- Is telomere shortening Related to Progeria?
- Is telomere shortening reversible? A clue from NASA’s Twin study.
- Knockdown of homeobox containing 1 increases the radiosensitivity of cervical cancer cells through telomere shortening
- Lack of age‐associated telomere shortening in long‐and short‐lived species of sea urchins
- Lack of telomerase causes telomere shortening in RA
- Lack of telomere shortening during senescence in Paramecium.
- Lack of telomere shortening with age in mouse resting zone chondrocytes
- Lactobacilli modulated AMPK activity and prevented telomere shortening in ageing rats
- L-carnosine reduces telomere damage and shortening rate in cultured normal fibroblasts
- Leucocyte telomere shortening in relation to newly diagnosed type 2 diabetic patients with depression
- Leucocyte telomere shortening is associated with nonalcoholic fatty liver disease‐related advanced fibrosis
- Leukocyte telomere Length Shortening and Alzheimer’s Disease Etiology
- Leukocyte telomere Length Shortening, hTERT Genetic Polymorphisms and Risk of Childhood Acute Lymphoblastic Leukemia
- Leukocyte telomere shortening in elderly Type2DM patients with previous myocardial infarction
- Leukocyte telomere shortening in grown-up patients with congenital heart disease
- Leukocyte telomere shortening in Huntington’s disease
- Leukocyte telomere shortening in staff working in cardiac catheterization laboratory
- Lifetime pesticide use and telomere shortening among male pesticide applicators in the Agricultural Health Study
- Limited telomere shortening in hematopoietic stem cells after transplantation
- Lineage-specific telomere shortening and unaltered capacity for telomerase expression in human T and B lymphocytes with age
- Lipid peroxidation-mediated telomere shortening in hydroxyl radical-induced apoptosis in HeLa cells
- Long G tails at both ends of human chromosomes suggest a C strand degradation mechanism for telomere shortening
- Longitudinal associations between metabolic syndrome components and telomere shortening
- Longitudinal telomere length shortening and cognitive and physical decline in later life: The Lothian Birth Cohorts 1936 and 1921
- Longitudinal telomere shortening and early Alzheimer’s disease progression in adults with down syndrome
- Longitudinal versus cross-sectional evaluations of leukocyte telomere length dynamics: age-dependent telomere shortening is the rule
- Long‐term follow‐up of recipients of allogeneic bone marrow grafts reveals no progressive telomere shortening and provides no evidence for haematopoietic stem …
- Long-term lymphoma survivors following high-dose chemotherapy and autograft: evidence of permanent telomere shortening in myeloid cells, associated with marked …
- Lower antioxidant capacity and elevated p53 and p21 may be a link between gender disparity in renal telomere shortening, albuminuria, and longevity
- LSC Abstract–Increased oxidative stress leads to telomere shortening in children with alpha-1 antitrypsin deficiency
- Luminal and cancer cells in the breast show more rapid telomere shortening than myoepithelial cells and fibroblasts
- Lung alveolar integrity is compromised by telomere shortening in telomerase-null mice
- Lung function and telomere shortening in blood leukocytes in clean-up workers of Chornobyl NPP suffered of COPD
- Mammalian telomere dynamics: healing, fragmentation shortening and stabilization
- Marked telomere shortening in mobilized peripheral blood progenitor cells (PBPC) following two tightly spaced high-dose chemotherapy courses with G-CSF
- Markers of cellular senescence. telomere shortening as a marker of cellular senescence
- Maternal smoking hastens telomere shortening in neonatal umbilical cord blood leukocytes
- Maternal‐fetal cross talk through cell‐free fetal DNA, telomere shortening, microchimerism, and inflammation
- Mathematical modeling confirms the length-dependency of telomere shortening
- Mathematical modeling of telomere shortening: an overview
- Mathematical modeling of vascular endothelial layer maintenance: the role of endothelial cell division, progenitor cell homing, and telomere shortening
- Mathematical Models and Computer Simulations of telomere shortening
- Mean leukocyte telomere length shortening and type 2 diabetes mellitus: a case-control study
- Measurement of telomere length in cells from pleural effusion: Asbestos exposure causes telomere shortening in pleural mesothelial cells
- Mechanism of acridine-based telomerase inhibition and telomere shortening
- Mechanism of p53 Accumulation and Activation by Ionizing Radiation and telomere shortening
- Mechanism of telomere shortening by oxidative stress
- Mechanism of telomere shortening in photoaging model induced by 8-methoxypsoralen and ultraviolet A
- Mechanisms of breast cancer risk in shift workers: association of telomere shortening with the duration and intensity of night work
- Mechanisms of telomere shortening in placentas from pregnancies complicated with intrauterine growth restriction
- Medaka fish exhibits longevity gender gap, a natural drop in estrogen and telomere shortening during aging: a unique model for studying sex-dependent …
- Microbiota and telomere shortening in gut-lung axis of human immunodeficiency virus infected donors
- Minimal Shortening of Leukocyte telomere Length Across Age Groups in a Cross-Sectional Study for Carriers of a Longevity-Associated FOXO3 Allele
- Mitogen stimulation cooperates with telomere shortening to activate DNA damage responses and senescence signaling
- MitoQ counteracts telomere shortening and elongates lifespan of fibroblasts under mild oxidative stress
- Modeling of the Process of telomere shortening: an Overview
- Modelling telomere shortening and the role of oxidative stress
- Moderate stem-cell telomere shortening rate postpones cancer onset in a stochastic model
- Monocyte telomere shortening and oxidative DNA damage in type 2 diabetes
- Mutated telomeres sensitize tumor cells to anticancer drugs independently of telomere shortening and mechanisms of telomere maintenance
- Mutations in XLF/NHEJ1/Cernunnos gene results in downregulation of telomerase genes expression and telomere shortening
- Nanoparticle mediated delivery of 2′-O-methyl-RNA leads to efficient telomerase inhibition and telomere shortening in human lung cancer cells
- Nestling telomere shortening, but not telomere length, reflects developmental stress and predicts survival in wild birds
- Neural Correlates and Peripheral miRNAs Associated with Stress-Related telomere shortening
- No evidence of substantia nigra telomere shortening in Parkinson’s disease
- No telomere shortening in marrow stroma from patients with MDS
- Nonmyeloablative conditioning does not prevent telomere shortening after allogeneic stem cell transplantation
- Novel and potent telomerase antagonist (GRN163L) inhibits telomerase activity, resulting in telomere shortening and apoptosis of multiple myeloma cells
- Novel biomolecules of ageing, sex differences and potential underlying mechanisms of telomere shortening in coronary artery disease
- Nutrition, oxidative damage, telomere shortening, and cellular senescence: individual or connected agents of aging?
- On telomere shortening in soft-tissue tumors
- On the origin of Robertsonian fusions in nature: evidence of telomere shortening in wild house mice
- OP20 Hepatocytes and cholangiocytes do not have significant telomere shortening with increasing chronological age in normal livers
- Organization of telomere sequences in birds: evidence for arrays of extreme length and for in vivo shortening
- Osteoarthritis and telomere shortening
- Oxidative DNA damage and telomere shortening
- Oxidative stress and telomere shortening in normal human fibroblasts after ir-radiation with X-rays
- Oxidative stress, telomere shortening, and DNA methylation in relation to low‐to‐moderate occupational exposure to welding fumes
- Oxidative stress‐induced renal telomere shortening as a mechanism of cyclosporine‐induced nephrotoxicity
- Oxidative stress-induced telomere length shortening of circulating leukocyte in patients with obstructive sleep apnea
- P-039: telomere shortening and/or “absence” may indicate dementia/AD status in older individuals with down syndrome
- P3995Advanced glycation end-products and telomere shortening contribute to cardiac aging: the relationship with myocardial strain
- P838Expression of miR-23a induces leukocyte telomere shortening and is associated with poor clinical outcomes in patients with coronary artery disease
- Parallel telomere shortening in multiple body tissues owing to malaria infection
- Patients with multiple sclerosis show increased oxidative stress markers and somatic telomere length shortening
- Pharmacodynamics of telomerase inhibition and telomere shortening by noncytotoxic suramin
- Phosphorylation of telomeric repeat binding factor 1 (TRF1) by Akt causes telomere shortening
- Placental Ageing in Adverse Pregnancy Outcomes: telomere shortening, Cell Senescence, and Mitochondrial Dysfunction
- Placental telomere shortening in stillbirth: a sign of premature senescence?
- Platinum (II) phenanthroimidazole G-quadruplex ligand induces selective telomere shortening in A549 cancer cells
- Poor maternal nutrition followed by accelerated postnatal growth leads to telomere shortening and increased markers of cell senescence in rat islets
- Potential CO2 effects on telomere shortening in Porites lutea & Method improvements for telomere assessment in corals
- Predictive factors and prognostic effect of telomere shortening in pulmonary fibrosis
- Premature telomere shortening and impaired regenerative response in hepatocytes of individuals with NAFLD
- Premature telomere shortening in polymorphonuclear neutrophils from patients with systemic lupus erythematosus is related to the lupus disease activity
- Prevalence of telomere shortening in familial and sporadic pulmonary fibrosis is increased in men
- Prevention of critical telomere shortening by oestradiol in human normal hepatic cultured cells and carbon tetrachloride induced rat liver fibrosis
- Prevention of Radiation-Induced telomere shortening, A Novel Mechanism Underlying Low-Dose Arsenic-Mediated Protection of Normal T-Lymphocytes
- Prevention Of telomere shortening
- Pro12Ala Polymorphism of the PPARγ2 Gene Interacts With a Mediterranean Diet to Prevent telomere shortening in the PREDIMED-NAVARRA Randomized Trial
- Progressive telomere shortening and telomerase reactivation during hepatocellular carcinogenesis
- Progressive telomere shortening is part of the natural history of chronic lymphocytic leukaemia and impacts clinical outcome: evidences from long term follow-up.
- Progressive telomere shortening occurs in cultured rat microglia, but not astrocytes
- Progressive telomere shortening of Epstein-Barr virus-specific memory T cells during HIV infection: contributor to exhaustion?
- Prostate stromal cell telomere shortening is associated with risk of prostate cancer in the placebo arm of the Prostate Cancer Prevention Trial
- Proteomic and microRNA data clarifying the effects of telomere shortening on cancer cells
- Proximity to roads, but not exposure to metal pollution, is associated with accelerated developmental telomere shortening in nestling great tits
- Race-related health disparities and biological aging: does rate of telomere shortening differ across blacks and whites?
- Radiation and chemotherapy bystander effects induce early genomic instability events: telomere shortening and bridge formation coupled with mitochondrial …
- Radiation-induced senescence-like growth arrest requires TP53 function but not telomere shortening
- Radiobiological effectiveness of ultrashort laser-driven Electron bunches: micronucleus frequency, telomere shortening and cell viability
- Rapid telomere shortening in children
- Rate of telomere shortening and cardiovascular damage: a longitudinal study in the 1946 British Birth Cohort
- RATE OF telomere shortening AND CARDIOVASCULAR PHENOTYPES
- Rate of telomere shortening and metabolic and cardiovascular risk factors: A longitudinal study in the 1934–44 Helsinki Birth Cohort Study
- Recent advances of Blood telomere length (BTL) shortening: A potential biomarker for development of cancer
- Relationship between microsatellite instability and telomere shortening in colorectal cancer
- Relationship between spontaneous or radiation-induced apoptosis and telomere shortening in G0 human lymphocytes
- Relationship between telomere shortening, genetic instability, and site of tumour origin in colorectal cancers
- Renal failure induces telomere shortening in the rat heart
- Replicative senescence as a model of aging: the role of oxidative stress and telomere shortening–an overview
- Replicative senescence of hematopoietic stem cells during serial transplantation: does telomere shortening play a role?
- Replicative senescence, telomere shortening and cell proliferation rate in Gaddi goat’s skin fibroblast cell line
- Resistance to senescence induction and telomere shortening by a G-quadruplex ligand inhibitor of telomerase
- Response to comments on is telomere shortening reversible? A clue from NASA’s twins mission
- Reversibility of defective hematopoiesis caused by telomere shortening in telomerase knockout mice
- Revisiting telomere shortening in Cancer
- Ribozyme-mediated telomerase inhibition induces immediate cell loss but not telomere shortening in ovarian cancer cells
- Robertsonian translocation as a result of telomere shortening during replicative senescence and immortalization of bovine oviduct epithelial cells
- Role of arterial telomere dysfunction in hypertension: relative contributions of telomere shortening and telomere uncapping
- Role of cell‐cycle turnover and oxidative stress in telomere shortening and cellular senescence in patients with chronic hepatitis C
- Role of Oxidative DNA Damage in telomere shortening and Cellular Aging
- Role of oxidative stress in telomere shortening in cultured fibroblasts from normal individuals and patients with ataxia–telangiectasia
- Role of shelterin proteins for telomere shortening in chronic lymphocytic leukemia
- Saccharomyces cerevisiae as a model to study replicative senescence triggered by telomere shortening
- Senescence and chromosomal instability induced by telomere shortening affect liver regeneration and hepatocarcinogenesis
- Senescence and telomere shortening induced by novel potent G-quadruplex interactive agents, quindoline derivatives, in human cancer cell lines
- Senescence occurs with hTERT repression and limited telomere shortening in human oral keratinocytes cultured with feeder cells
- Senescence, telomere shortening and telomere maintenance
- Sepsis induces telomere shortening: a potential mechanism responsible for delayed pathophysiological events in sepsis survivors?
- Sex-dependent telomere shortening, telomerase activity and oxidative damage in marine medaka Oryzias melastigma during aging
- Shortening of telomere length by metabolic factors in diabetes: protective effects of fenofibrate
- Shortening telomere is associated with subclinical atherosclerosis biomarker in omnivorous but not in vegetarian healthy men
- Significant telomere shortening in acute and chronic leukemia
- Significant telomere shortening in childhood leukemia
- Site‐specific DNA damage at GGG sequence by oxidative stress may accelerate telomere shortening
- Site-specific DNA damage at the GGG sequence by UVA involves acceleration of telomere shortening
- Six-year telomere shortening is associated with increased incidence of subclinical carotid vascular damage and cardiovascular prognosis
- Slow‐down of age‐dependent telomere shortening is executed in human skin keratinocytes by hormesis‐like‐effects of trace hydrogen peroxide or by anti‐oxidative …
- SORBS2 transcription is activated by telomere position effect–over long distance upon telomere shortening in muscle cells from patients with facioscapulohumeral …
- Stochastic mechanism of cellular aging—abrupt telomere shortening as a model for stochastic nature of cellular aging
- Stochastic modeling of length-dependent telomere shortening in Corvus monedula
- Stochastic Modeling of telomere Biology: Probabilistic Analysis of telomere shortening and Network-Based Approach to Gene Expression Analysis
- Stochastic modelling in molecular biology: a probabilistic analysis of protein polymerisation and telomere shortening
- Stochastic modelling of length dependent telomere shortening in
- Stochastic models of telomere shortening
- Stochastic telomere shortening and the Route to Limitless Replicative Potential
- Stochastic variation in telomere shortening rate causes heterogeneity of human fibroblast replicative life span
- Stress and telomere shortening among central Indian conservation refugees
- Stress induced telomere shortening: longer life with less mutations?
- Stress resilience: Narrative identity may buffer the longitudinal effects of chronic caregiving stress on mental health and telomere shortening
- Subclinical inflammation, telomere shortening, homocysteine, vitamin B6, and mortality: the Ludwigshafen Risk and Cardiovascular Health Study
- Substantial telomere shortening in the substantia nigra of telomerase-deficient mice does not increase susceptibility to MPTP-induced dopamine depletion
- Supplemental Data telomere shortening Triggers Senescence of Human Cells through a Pathway Involving ATM, p53, and p21CIP1, but Not p16INK4a
- Suppression of Ku80 correlates with radiosensitivity and telomere shortening in the U2OS telomerase-negative osteosarcoma cell line
- Syndromes Associated with telomere shortening
- Syndromes of telomere shortening
- T cell renewal rates, telomerase, and telomere length shortening
- Telomerase activation in mouse mammary tumors: lack of detectable telomere shortening and evidence for regulation of telomerase RNA with cell proliferation.
- Telomerase does not counteract telomere shortening but protects mitochondrial function under oxidative stress
- Telomerase gene mutations and telomere length shortening in patients with idiopathic pulmonary fibrosis in a C hinese population
- Telomerase inhibition by 3′-azido-2′, 3′-dideoxynucleoside 5′-triphosphates and telomere shortening in human cultured cells by the corresponding nucleosides
- Telomerase Inhibition, telomere shortening, and Cellular Uptake of the Perylene Derivatives PM2 and PIPER in Prostate Cancer Cells
- Telomerase Inhibition, telomere shortening, and Decreased Cell Proliferation by Cell Permeable 2′-O-Methoxyethyl Oligonucleotides
- Telomerase inhibition, telomere shortening, and senescence of cancer cells by tea catechins
- Telomerase inhibition, telomere shortening, cell growth suppression and induction of apoptosis by telomestatin in childhood neuroblastoma cells
- Telomerase regulation and progressive telomere shortening of rat hepatic stem-like epithelial cells during in vitro aging
- telomere and its role in the aging pathways: telomere shortening, cell senescence and mitochondria dysfunction
- telomere G-quadruplex as a potential target to accelerate telomere shortening by expanding the incomplete end-replication of telomere DNA
- telomere Length Inheritance and Shortening in Trisomy 21
- telomere length maintenance, shortening, and lengthening
- telomere length shortening and gastric cancer risk in a high risk Polish population
- telomere length shortening in Alzheimer’s disease: procedures for a causal investigation using single nucleotide polymorphisms in a mendelian randomization study
- telomere length shortening in gastric mucosa is a field effect associated with increased risk of gastric cancer
- telomere length shortening in Langerhans cell histiocytosis
- telomere Length Shortening in Malignant Patients Undergoing Chemotherapy
- telomere length shortening in non-Hodgkin’s lymphoma patients undergoing chemotherapy
- telomere length shortening in patients with dementia with Lewy bodies
- telomere length shortening is associated with disease evolution in chronic myelogenous leukemia
- telomere length shortening is associated with treatment-free remission in chronic myeloid leukemia patients
- telomere length shortening of peripheral blood mononuclear cells in solid-cancer patients undergoing standard-dose chemotherapy might be correlated with good …
- telomere longitudinal shortening as a biomarker for dementia status of adults with Down syndrome
- telomere position effect: regulation of gene expression with progressive telomere shortening over long distances
- telomere shortening & metabolic/vascular diseases
- telomere shortening Abrogates Dentate Gyrus Neurogenesis But Improves Alzheimer’S Disease Progression In Mice
- telomere shortening accompanies increased cell cycle activity during serial transplantation of hematopoietic stem cells
- telomere shortening activates TGF-β/Smads signaling in lungs and enhances both lipopolysaccharide and bleomycin-induced pulmonary fibrosis
- telomere shortening alters the kinetics of the DNA damage response after ionizing radiation in human cells
- telomere shortening among male applicators in the Agricultural Health Study
- telomere shortening and accelerated aging in COPD: findings from the BODE cohort
- telomere shortening and age estimation in forensic medicine
- telomere shortening and ageing
- telomere shortening and ageing of the immune system
- telomere shortening and Alzheimer’s disease
- telomere shortening and aortic plaque progression in Apoliprotein E knockout mice after pulmonary exposure to candle light combustion particles
- telomere shortening and apoptosis in telomerase-inhibited human tumor cells
- telomere shortening and associated chromosomal instability in peripheral blood lymphocytes of patients with Hodgkin’s lymphoma prior to any treatment are …
- telomere shortening and atherosclerosis
- telomere shortening and cell cycle arrest in Trypanosoma brucei expressing human telomeric repeat factor TRF1
- telomere shortening and cell cycle arrest induced by p16 gene introduction in human breast cancer MCF-7 cells
- telomere shortening and cell fates in mouse models of neoplasia
- telomere shortening and cell senescence induced by perylene derivatives in A549 human lung cancer cells
- telomere shortening and cellular senescence in a model of chronic renal allograft rejection
- telomere shortening and chromosomal abnormalities in intestinal metaplasia of the urinary bladder
- telomere shortening and chromosomal instability abrogates proliferation of adult but not embryonic neural stem cells
- telomere shortening and chromosomal instability in myelodysplastic syndromes
- telomere shortening and decline in replicative potential as a function of donor age in human adrenocortical cells
- telomere shortening and decreased replicative potential, contrasted by continued proliferation of telomerase-positive CD8+ CD28lo T cells in patients with systemic …
- telomere shortening and DNA damage of embryonic stem cells induced by cigarette smoke
- telomere shortening and frailty in Mexican older adults
- telomere shortening and Growth Inhibition of Human Cancer Cells by Novel Synthetic Telomerase Inhibitors MST-312, MST-295, and MST-199 1 Supported in part …
- telomere shortening and haemodialysis
- telomere shortening and immune activity in war veterans with posttraumatic stress disorder
- telomere shortening and inactivation of cell cycle checkpoints characterize human hepatocarcinogenesis
- telomere shortening and increased oxidative stress are restricted to venous tissue in patients with varicose veins: A merely local disease?
- telomere shortening and ionizing radiation: a possible role in vascular dysfunction?
- telomere shortening and karyotypic alterations in hepatocytes in long‐term transplanted human liver allografts
- telomere shortening and loss of self-renewal in dyskeratosis congenita induced pluripotent stem cells
- telomere shortening and metabolic compromise underlie dystrophic cardiomyopathy
- telomere shortening and mitotic dysfunction generate cytogenetic heterogeneity in a subgroup of renal cell carcinomas
- telomere shortening and mood disorders: preliminary support for a chronic stress model of accelerated aging
- telomere shortening and oxidative stress in aged macrophages results in impaired STAT5a phosphorylation
- telomere shortening and oxidative stress in patients with COPD
- telomere shortening and p21-checkpoint inactivation characterize multistep hepatocarcinogenesis in humans
- telomere shortening And Progression In Patients With Chronic Obstructive Pulmonary Disease (COPD)
- telomere shortening and regenerative capacity after acute kidney injury
- telomere shortening and stem cell failure in dyskeratosis congenita
- telomere shortening and survival in free-living corvids
- telomere shortening and Telomerase Activation during Cancer Formation
- telomere shortening and telomerase activity in ischaemic cardiomyopathy patients–potential markers of ventricular arrhythmia
- telomere shortening and telomerase expression during multistage carcinogenesis of intraductal papillary mucinous neoplasms of the pancreas
- telomere shortening and telomerase reactivation in dysplastic nodules of human hepatocarcinogenesis
- telomere shortening and telomerase reverse transcriptase expression in preinvasive bronchial lesions
- telomere shortening and telomere position effect in mild ring 17 syndrome
- telomere shortening and the clinicopathologic characteristics of human colorectal carcinomas
- telomere shortening and the population size-dependency of life span of human cell culture: further implication for two proliferation-restricting telomeres
- telomere shortening and tumor formation by mouse cells lacking telomerase RNA
- telomere shortening as a genetic risk factor for the development of cirrhosis
- telomere shortening as a hallmark of stem cell senescence
- telomere shortening as a mechanism of long-term cost of infectious diseases in natural animal populations
- telomere shortening as genetic risk factor of liver cirrhosis
- telomere shortening associated with chromosome instability is arrested in immortal cells which express telomerase activity.
- telomere shortening associated with disease evolution patterns in myelodysplastic syndromes
- telomere shortening associated with increased genomic complexity in chronic lymphocytic leukemia
- telomere shortening associated with increased levels of oxidative stress in sulfur mustard-exposed Iranian veterans
- telomere shortening Behind the Harm of Immunosuppressive Therapy In Idiopathic Pulmonary Fibrosis
- telomere shortening by cisplatin in yeast nucleotide excision repair mutant
- telomere shortening by mutations in the RTEL1 helicase cause severe form of dyskeratosis congenita, Hoyerall-Hreidarsson syndrome.
- telomere shortening By Terc Knockout in the Eµ-TCL1 Transgenic Murine Model of CLL: Characterization of Disease Development and Survival
- telomere shortening by transgenerational transmission of TNF-α-induced TERRA via ATF7
- telomere shortening correlates to dysplasia but not to DNA aneuploidy in longstanding ulcerative colitis
- telomere shortening correlates with increasing aneuploidy of chromosome 8 in human hepatocellular carcinoma
- telomere shortening correlates with leukemic stem cell burden at diagnosis of chronic myeloid leukemia
- telomere shortening correlates with prognostic score at diagnosis and proceeds rapidly during progression of chronic myeloid leukemia
- telomere shortening distinguishes inverted urothelial neoplasms
- telomere shortening does not occur during postmaturational aging in situ in normal human oral fibroblasts
- telomere shortening during aging of human osteoblasts in vitro and leukocytes in vivo: lack of excessive telomere loss in osteoporotic patients
- telomere shortening during aging: attenuation by antioxidants and anti-inflammatory agents
- telomere shortening Exposes Functions
- telomere shortening exposes functions for the mouse Werner and Bloom syndrome genes
- telomere shortening impairs organ regeneration by inhibiting cell cycle re‐entry of a subpopulation of cells
- telomere shortening impairs regeneration of the olfactory epithelium in response to injury but not under homeostatic conditions
- telomere shortening in a long-lived marine bird: cross-sectional analysis and test of an aging tool
- telomere shortening in a Telomerase Null Mouse Model Restores Susceptibility to Bleomycin-Induced Lung Fibrosis.
- telomere shortening in Aging, Coronary Heart Disease and Cerebrovascular Diseases [J]
- telomere shortening in alcohol dependence: Roles of alcohol and acetaldehyde
- telomere shortening in alveolar macrophages of smokers and COPD patients
- telomere shortening in Alzheimer’s disease patients
- telomere shortening in atherosclerosis
- telomere shortening in Barrett’s mucosa and esophageal adenocarcinoma and its association with loss of heterozygosity
- telomere shortening in blood leukocytes of patients with chronic obstructive pulmonary disease
- telomere shortening in blood leukocytes of patients with posttraumatic stress disorder
- telomere shortening in breast cancer cells (MCF7) under treatment with low doses of the benzylisoquinoline alkaloid chelidonine
- telomere shortening in breast cancer correlates with the pathological features of tumor progression
- telomere shortening in cancer cells by electrolyzed-reduced water
- telomere shortening in centroacinar-acinar region of the pancreas: relationships with aging, cancers and tissue stem cells
- telomere shortening in chronic liver diseases
- telomere shortening in chronic obstructive pulmonary disease
- telomere shortening in CLL Correlates with Cell Cycle-Dependent Dysregulation of Shelterin Proteins
- telomere shortening In COPD And Lung Cancer: A Pilot Study In Chronic Smokers
- telomere shortening in cultured autografts of patients with burns
- telomere shortening in cultured human dermal fibroblasts is associated with acute photodamage induced by UVA irradiation
- telomere shortening in diabetic rats: effects of dietary intervention with fisetin and n-acetylcysteine
- telomere shortening in diaphragm and tibialis anterior muscles of aged mdx mice
- telomere shortening in Down Syndrome Patients—When Does It Start?
- telomere shortening in elderly individuals with mild cognitive impairment may be attenuated with ω-3 fatty acid supplementation: a randomized controlled pilot study
- telomere shortening in elderly individuals with mild cognitive impairment may be attenuated with¿-3 fatty acid supplementation: a randomized controlled pilot study
- telomere shortening in elderly people with mild cognitive impairment may be attenuated with omega-3 fatty acid supplementation: A randomised controlled pilot …
- telomere shortening in endothelial and progenitor cells likely to play a crucial role in the development of vascular disease
- telomere shortening in familial and sporadic pulmonary fibrosis
- telomere shortening in Fanconi anaemia demonstrated by a direct FISH approach
- telomere shortening in formerly abused and never abused women
- telomere shortening in gastric carcinoma with aging despite telomerase activation
- telomere shortening in Hematological Malignancies with Tetraploidization—A Mechanism for Chromosomal Instability?
- telomere shortening in hematopoietic stem cell transplantation: a potential mechanism for late graft failure?
- telomere shortening in human coronary artery diseases
- telomere shortening in human diseases
- telomere shortening in human fibroblasts is not dependent on the size of the telomeric-3′-overhang
- telomere shortening in human fibroblasts is not dependent on the size of the telomeric‐3′‐overhang
- telomere shortening in human HL60 cells by treatment with 3′-azido-2′, 3′-dideoxynucleosides and telomerase inhibition by their 5′-triphosphates
- telomere shortening in human HL60 cells by treatment with deoxyguanosine analogs
- telomere shortening in human kidney-The key to the adverse effects of donor age?
- telomere shortening in intra uterine growth restriction placentas
- telomere shortening in kidneys with age
- telomere shortening in leucocyte subsets of long‐term survivors of allogeneic bone marrow transplantation
- telomere shortening in leukemic cells is related to their genetic alterations but not replicative capability
- telomere shortening in leukocyte subpopulations from baboons
- telomere shortening in leukocyte subpopulations in depression
- telomere shortening in liver transplant recipients is not influenced by underlying disease or metabolic derangements.
- telomere shortening in middle-aged men with sleep-disordered breathing
- telomere shortening in mouse strains with constitutional chromosomal aberrations
- telomere shortening in mTR−/− embryos is associated with failure to close the neural tube
- telomere shortening in mucosa surrounding the tumor: biosensor of field cancerization and prognostic marker of mucosal failure in head and neck squamous cell …
- telomere shortening in neural stem cells disrupts neuronal differentiation and neuritogenesis
- telomere shortening in neurological disorders: an abundance of unanswered questions
- telomere shortening in non-tumorous and tumor mucosa is independently related to colorectal carcinogenesis in precancerous lesions
- telomere shortening in pancreatic cancer is correlated to KRAS mutation
- telomere shortening in patients with plasma cell disorders
- telomere shortening in peripheral blood cells was related with aging but not with white blood cell count
- telomere shortening In Peripheral Skeletal Muscle Of Patient With Chronic Obstructive Pulmonary Disease
- telomere shortening in Ph-negative chronic myeloproliferative neoplasms: a biological marker of polycythemia vera and myelofibrosis, regardless of …
- telomere shortening in placentas from pregnancies complicated with diabetes
- telomere shortening in rat hepatic stem-like epithelial cells and subcellular localization of rat PinX1
- telomere shortening in recipients of bone-marrow transplants
- telomere shortening in renal cell carcinoma
- telomere shortening in sleep apnea syndrome
- telomere shortening in smokers with and without COPD
- telomere shortening in stillbirth: a sign of premature placental senescence
- telomere shortening in T cells correlates with Alzheimer’s disease status
- telomere shortening in T lymphocytes of older individuals with Down syndrome and dementia
- telomere shortening in the Alzheimer’s disease neuroimaging initiative cohort
- telomere shortening in the colonial coral Acropora digitifera during development
- telomere shortening in the colonic mucosa of patients with ulcerative colitis
- telomere shortening in the damaged small bile ducts in primary biliary cirrhosis reflects ongoing cellular senescence
- telomere shortening in the esophagus of Japanese alcoholics: relationships with chromoendoscopic findings, ALDH2 and ADH1B genotypes and smoking …
- telomere shortening in the Oral Epithelium in Relation to Alcohol Intake, Alcohol Dehydrogenase (ADH‐1B) and Acetaldehyde Dehydrogenase (ALDH‐2) Genotypes …
- telomere shortening in the pathogenesis of nasopharyngeal carcinoma
- telomere shortening in type II pneumocytes relates to idiopathic pulmonary fibrosis
- telomere shortening in uterine leiomyomas
- telomere shortening in women resident close to waste landfill sites
- telomere shortening induces cell intrinsic checkpoints and environmental alterations limiting adult stem cell function
- telomere shortening is a hallmark of genetic cardiomyopathies
- telomere shortening is a prognostic factor in chronic hepatitis C virus infection
- telomere shortening is a sole mechanism of aging in mammals
- telomere shortening is an early somatic DNA alteration in human prostate tumorigenesis
- telomere shortening is an in vivo marker of myocyte replication and aging
- telomere shortening is associated to TRF1 and PARP1 overexpression in Duchenne muscular dystrophy
- telomere shortening is associated with cell division in vitro and in vivo
- telomere shortening is associated with genetic anticipation in Chinese Von Hippel–Lindau disease families
- telomere shortening is associated with malformation in p53-deficient mice after irradiation during specific stages of development
- telomere shortening is associated with poor prognosis and telomerase activity correlates with DNA repair impairment in non-small cell lung cancer
- telomere shortening is associated with reduced duodenal HCO3− secretory but normal gastric acid secretory capacity in aging mice
- telomere shortening is correlated with the DNA damage response and telomeric protein down-regulation in colorectal preneoplastic lesions
- telomere shortening is nearly universal in pancreatic intraepithelial neoplasia
- telomere shortening is proportional to the size of the G-rich telomeric 3′-overhang
- telomere shortening is the sole mechanism of aging
- telomere shortening leads to an acceleration of synucleinopathy and impaired microglia response in a genetic mouse model
- telomere shortening leads to earlier age of onset in ALS mice
- telomere shortening may be associated with human keloids
- telomere shortening may contribute to aging and cancer: a perspective
- telomere shortening mechanisms
- telomere shortening occurs early during breast tumorigenesis: a cause of chromosome destabilization underlying malignant transformation?
- telomere shortening occurs early during gastrocarcinogenesis
- telomere shortening occurs in Asian Indian Type 2 diabetic patients
- telomere shortening occurs in subsets of normal breast epithelium as well as in situ and invasive carcinoma
- telomere shortening of epithelial cells characterises the adenoma-carcinoma transition of human colorectal cancer
- telomere shortening of MCF 7 Cells Caused by Antisense Telomerase cDNA
- telomere shortening of MCF-7 Cells Caused by Antisense Telomerase cDNA.
- telomere shortening of peripheral blood mononuclear cells in coronary disease patients with metabolic disorders
- telomere shortening over 6 years is associated with increased subclinical carotid vascular damage and worse cardiovascular prognosis in the general population
- telomere shortening produces an inflammatory environment that promotes tumor invasiveness in zebrafish
- telomere shortening rate predicts species life span
- telomere shortening reduces Alzheimer’s disease amyloid pathology in mice
- telomere shortening Reduces Regenerative Capacity after Acute Kidney Injury
- telomere shortening reduces Survival despite Suppression of Carcinoma Formation during Chronic Liver Damage
- telomere shortening relaxes X chromosome inactivation and forces global transcriptome alterations
- telomere shortening sensitizes cancer cells to selected cytotoxic agents: in vitro and in vivo studies and putative mechanisms
- telomere shortening triggers a feedback loop to enhance end protection
- telomere shortening triggers a p53-dependent cell cycle arrest via accumulation of G-rich single stranded DNA fragments
- telomere shortening triggers senescence of human cells through a pathway involving ATM, p53, and p21CIP1, but not p16INK4a
- telomere shortening unrelated to smoking, body weight, physical activity, and alcohol intake: 4,576 general population individuals with repeat measurements …
- telomere shortening with aging in human esophageal mucosa
- telomere shortening with aging in human liver
- telomere shortening with aging in human thyroid and parathyroid tissue
- telomere shortening with aging in the human pancreas
- telomere shortening, ageing, and chromosome damage
- telomere shortening, atherosclerosis, and metabolic syndrome
- telomere shortening, clonal evolution and disease progression in myelodysplastic syndrome patients with 5q deletion treated with lenalidomide
- telomere shortening, inflammatory cytokines, and anti-cytomegalovirus antibody follow distinct age-associated trajectories in humans
- telomere shortening, regenerative capacity, and cardiovascular outcomes
- telomere shortening, telomerase expression, and chromosome instability in rat hepatic epithelial stem‐like cells
- telomere shortening, TP53 mutations and deletions in chronic lymphocytic leukemia result in increased chromosomal instability and breakpoint clustering in …
- telomere shortening: a biological marker of sporadic colorectal cancer with normal expression of p53 and mismatch repair proteins
- telomere shortening: a diagnostic tool and therapeutic target for cardiovascular disease?
- telomere shortening: A marker of atherosclerosis?
- telomere shortening: a new prognostic factor for cardiovascular disease post-radiation exposure
- telomere shortening: significant for keratinocyte grafting?
- telomere shortening: The main mechanism of natural and radiation aging
- telomere structure and shortening in telomerase-deficient Trypanosoma brucei
- telomere Structure and Shortening in Telomerase-Deficient Trypanosoma brucei: Implications for Anitgenic Variation
- telomere uncapping in progenitor cells with critical telomere shortening is coupled to S-phase progression in vivo
- Telomeric noncoding RNA TERRA is induced by telomere shortening to nucleate telomerase molecules at short telomeres
- TERRA promotes telomere shortening through exonuclease 1–mediated resection of chromosome ends
- TGF-beta receptor mediated telomerase inhibition, telomere shortening and breast cancer cell senescence
- The aging lung: tissue telomere shortening in health and disease
- The association between statins and telomere shortening
- The association of occupational metals exposure and oxidative damage, telomere shortening in fitness equipments manufacturing workers
- The effect of pro-inflammatory conditioning and/or high glucose on telomere shortening of aging fibroblasts
- The effects of telomere shortening on cancer cells: a network model of proteomic and microRNA analysis
- The interaction effects of polycyclic aromatic hydrocarbons exposure and TERT-CLPTM1L variants on longitudinal telomere length shortening: A prospective cohort …
- The Pro12Ala polymorphism of the PPARγ2 gene interacts with a Mediterranean Diet to prevent telomere shortening in the PREDIMED-NAVARRA randomized trial
- The rate of leukocyte telomere shortening predicts mortality from cardiovascular disease in elderly men
- The rate of leukocyte telomere shortening predicts mortality from cardiovascular disease in elderly men: a novel demonstration
- The role of telomere shortening in carcinogenesis: A hybrid stochastic-deterministic approach
- The role of telomere shortening in somatic stem cells and tissue aging: lessons from telomerase model systems
- The role of telomere shortening in the development and progression of COPD
- The roles of senescence and telomere shortening in cardiovascular disease
- The shortening of leukocyte telomere length relates to DNA hypermethylation of LINE-1 in type 2 diabetes mellitus
- The shortening telomere length of T lymphocytes maybe associated with hyper‑function in servere aplastic anemia
- The teleost Oryzias latipes shows telomere shortening with age despite considerable telomerase activity throughout life
- The telomerase inhibitor telomestatin induces telomere shortening and cell death in Arabidopsis
- The telomere shortening signal may be explained by a fountain mechanism modulating the expression of eukaryotic genes
- The THO complex component Thp2 counteracts telomeric R‐loops and telomere shortening
- The two isomers of HDTIC compounds from Astragali Radix slow down telomere shortening rate via attenuating oxidative stress and increasing DNA repair ability in …
- The Yeast TEL1 Gene Partially Substitutes for Human ATM in Suppressing Hyperrecombination, Radiation-Induced Apoptosis and telomere shortening in AT Cells
- Thymoquinone induces telomere shortening, DNA damage and apoptosis in human glioblastoma cells
- T-loop formation and abrupt telomere shortening
- Tomentosin Induces telomere shortening and Caspase‐Dependant Apoptosis in Cervical Cancer Cells
- Topical application of preparations containing DNA repair enzymes prevents ultraviolet-induced telomere shortening and c-FOS proto-oncogene hyperexpression in …
- TRF2 overexpression diminishes repair of telomeric single-strand breaks and accelerates telomere shortening in human fibroblasts
- triphosphates inhibit telomerase activity in vitro , and the corresponding nucleosides cause telomere shortening in human HL60 cells
- Two consecutive courses of peripheral blood progenitor cell (PBPC) mobilization induce marked telomere length shortening
- Uncoupling the senescent phenotype from telomere shortening in hydrogen peroxide-treated fibroblasts
- Up-regulation of telomere-binding proteins, TRF1, TRF2, and TIN2 is related to telomere shortening during human multistep hepatocarcinogenesis
- Urothelial cell senescence is not linked with telomere shortening
- WRN controls formation of extrachromosomal telomeric circles and is required for TRF2ΔB-mediated telomere shortening
- XAV939 promotes apoptosis in a neuroblastoma cell line via telomere shortening
- XPF with mutations in its conserved nuclease domain is defective in DNA repair but functions in TRF2-mediated telomere shortening
- Zscan4 is activated after telomere shortening in mouse embryonic stem cells
- γ-Tocotrienol prevents oxidative stress-induced telomere shortening in human fibroblasts derived from different aged individuals
