QUERCETIN
December 21, 2023GASTROPROTECTION
December 21, 2023
- Pregabalin reduces cocaine self‐administration and relapse to cocaine seeking in the rat
- The 5-HT2C receptor agonist lorcaserin reduces cocaine self–administration, reinstatement of cocaine-seeking and cocaine induced locomotor activity
- Transcranial magnetic stimulation of medial prefrontal and cingulate cortices reduces cocaine self–administration: a pilot study
- Pharmacological stimulation of group ii metabotropic glutamate receptors reduces cocaine self–administration and cocaine-induced reinstatement of drug seeking in …
- The 5-HT2C receptor agonist Ro60-0175 reduces cocaine self–administration and reinstatement induced by the stressor yohimbine, and contextual cues
- Injection of CART (cocaine-and amphetamine-regulated transcript) peptide into the nucleus accumbens reduces cocaine self–administration in rats
- PPL-138 (BU10038): A bifunctional NOP/mu partial agonist that reduces cocaine self–administration in rats
- Systemic delivery of a brain-penetrant TrkB antagonist reduces cocaine self–administration and normalizes TrkB signaling in the nucleus accumbens and prefrontal …
- Cebranopadol, a mixed opioid agonist, reduces cocaine self–administration through nociceptin opioid and mu opioid receptors
- Modified single prolonged stress reduces cocaine self–administration during acquisition regardless of rearing environment
- The hypocretin–orexin system regulates cocaine self‐administration via actions on the mesolimbic dopamine system
- The glucagon-like peptide 1 (GLP-1) receptor agonist exendin-4 reduces cocaine self–administration in mice
- Potent and selective NOP receptor activation reduces cocaine self‐administration in rats by lowering hedonic set point
- Cebranopadol reduces cocaine self–administration in male rats: Dose, treatment and safety consideration
- LSP2-9166, an orthosteric mGlu4 and mGlu7 receptor agonist, reduces cocaine self–administration under a progressive ratio schedule in rats
- The effects of aerobic exercise on cocaine self–administration in male and female rats
- Hypocretin/Orexin regulation of dopamine signaling and cocaine self–administration is mediated predominantly by hypocretin receptor 1
- Naltrexone–buprenorphine interactions: effects on cocaine self–administration
- Gamma-hydroxybutyric acid decreases intravenous cocaine self–administration in rats
- (-)-Stepholidine reduces cue-induced reinstatement of cocaine seeking and cocaine self–administration in rats
- Amphetamine maintenance therapy during intermittent cocaine self–administration in rats attenuates psychomotor and dopamine sensitization and reduces addiction …
- Hypocretin neurotransmission within the central amygdala mediates escalated cocaine self–administration and stress-induced reinstatement in rats
- Doses of GBR12909 that suppress cocaine self‐administration in non‐human primates substantially occupy dopamine transporters as measured by [11C] WIN35,428 …
- Oxytocin reduces cocaine seeking and reverses chronic cocaine-induced changes in glutamate receptor function
- Selective inhibition of M5 muscarinic acetylcholine receptors attenuates cocaine self‐administration in rats
- Knockdown of hypocretin attenuates extended access of cocaine self–administration in rats
- Cholinergic influence on intravenous cocaine self–administration by rhesus monkeys
- Neuroadaptations in the cellular and postsynaptic group 1 metabotropic glutamate receptor mGluR5 and Homer proteins following extinction of cocaine self …
- α4β2 Nicotinic receptor desensitizing compounds can decrease self–administration of cocaine and methamphetamine in rats
- Ibudilast attenuates cocaine self–administration and prime-and cue-induced reinstatement of cocaine seeking in rats
- The effects of chronic buprenorphine on intake of heroin and cocaine in rats and its effects on nucleus accumbens dopamine levels during self–administration
- The melanin-concentrating hormone system modulates cocaine reward
- Reciprocal inhibitory effects of intravenous d-methamphetamine self–administration and wheel activity in rats
- Agents in development for the management of cocaine abuse
- Group II metabotropic glutamate receptors in the striatum of non-human primates: dysregulation following chronic cocaine self–administration
- Withdrawal from cocaine self–administration and Yoked cocaine Delivery Dysregulates Glutamatergic mGlu5 and NMDA Receptors in the Rat Brain
- Intermittent cocaine self–administration has sex-specific effects on addiction-like behaviors in rats
- cocaine self–administration punished by iv histamine in rat models of high and low drug abuse vulnerability: effects of saccharin preference, impulsivity, and sex
- Abstract# 157: Transcranial Magnetic Stimulation of Medial Prefrontal and Cingulate Cortices reduces cocaine self–administration
- Effects of chronic buspirone treatment on cocaine self–administration
- Risperidone diminishes cocaine-induced craving
- Effects of lorcaserin and buspirone, administered alone and as a mixture, on cocaine self–administration in male and female rhesus monkeys.
- Effects of cocaine self–administration and its extinction on the rat brain cannabinoid CB1 and CB2 receptors
- Overexpression of CREB in the nucleus accumbens shell increases cocaine reinforcement in self-administering rats
- Effects of l-methamphetamine treatment on cocaine– and food-maintained behavior in rhesus monkeys
- Alternative reinforcer response cost impacts cocaine choice in humans
- N-acetylaspartylglutamate (NAAG) inhibits intravenous cocaine self–administration and cocaine-enhanced brain-stimulation reward in rats
- The effects of oral micronized progesterone on smoked cocaine self–administration in women
- Preclinical evidence for GABAB agonists as a pharmacotherapy for cocaine addiction
- The effect of chronic amphetamine treatment on cocaine-induced facilitation of intracranial self-stimulation in rats
- Safety and tolerability of intranasal cocaine during phendimetrazine maintenance
- #VALUE!
- Modulation of cocaine and food self–administration by low-and high-efficacy D1 agonists in squirrel monkeys
- Beta-caryophyllene inhibits cocaine addiction-related behavior by activation of PPARα and PPARγ: Repurposing a FDA-approved food additive for cocaine use …
- Investigating DAT uptake inhibitors as potential replacement therapies for cocaine
- Preclinical research on cocaine self–administration: environmental determinants and their interaction with pharmacological treatment
- Effects of progesterone and testosterone on cocaine self–administration and cocaine discrimination by female rhesus monkeys
- Differential effects of the metabotropic glutamate 2/3 receptor agonist LY379268 on nicotine versus cocaine self–administration and relapse in squirrel monkeys
- Ketoconazole increases cocaine and opioid use in methadone maintained patients
- Effects of chronic buprenorphine treatment on levels of nucleus accumbens glutamate and on the expression of cocaine-induced behavioral sensitization in rats
- Cannabidiol (CBD) reduces cocaine-environment memory in mice
- Intermittent access cocaine self–administration produces context-specific escalation and increased motivation
- Alprazolam and oxazepam block the cue-induced reinstatement of extinguished cocaine seeking in rats
- A combination of buprenorphine and naltrexone blocks compulsive cocaine intake in rodents without producing dependence
- Hypocretin (orexin) facilitates reward by attenuating the antireward effects of its cotransmitter dynorphin in ventral tegmental area
- Buprenorphine treatment of opiate and cocaine abuse: clinical and preclinical studies
- Cannabidiol effects on cocaine-seeking behaviour and incubation of craving in mice
- Deletion of the serotonin transporter perturbs BDNF signaling in the central amygdala following long-access cocaine self–administration
- Cannabidiol decreases motivation for cocaine in a behavioral economics paradigm but does not prevent incubation of craving in mice
- cocaine self–administration and locomotor activity are altered in Lewis and F344 inbred rats by RTI 336, a 3-phenyltropane analog that binds to the dopamine …
- self administration of cocaine in monkeys receiving LAAM acutely or chronically
- Acamprosate attenuates cocaine-and cue-induced reinstatement of cocaine-seeking behavior in rats
- Amphetamine maintenance therapy during intermittent cocaine self–administration in rats: reduction of addiction-like behavior is associated with attenuation of …
- Knockdown of Hypocretin/Orexin Attenuates Extended-Access cocaine self–administration in Rats
- Behavioral Economic Demand for cocaine During Phendimetrazine Maintenance in Humans
- Cannabidiol attenuates the rewarding effects of cocaine in rats by CB2, 5-HT1A and TRPV1 receptor mechanisms
- BP 897, a Selective Dopamine D3 Receptor Ligand with Therapeutic Potential for the Treatment of cocaine‐Addiction
- Estradiol as a mechanism for sex differences in the development of an addicted phenotype following extended access cocaine self–administration
- GABA mechanisms in the pedunculopontine tegmental nucleus influence particular aspects of nicotine self–administration selectively in the rat
- Effects of acupuncture on stress-induced relapse to cocaine-seeking in rats
- Augmented acquisition of cocaine self–administration and altered brain glucose metabolism in adult female but not male rats exposed to a cannabinoid …
- Hypocretin receptor 1 blockade produces bimodal modulation of cocaine-associated mesolimbic dopamine signaling
- Design and synthesis of an orally active metabotropic glutamate receptor subtype-2 (mGluR2) positive allosteric modulator (PAM) that decreases cocaine self …
- Hypocretin receptor 1 knockdown in the ventral tegmental area attenuates mesolimbic dopamine signaling and reduces motivation for cocaine
- Buprenorphine-induced alterations of cocaine‘s reinforcing effects in rhesus monkey: a dose-response analysis
- Addiction-related alterations in D1 and D2 dopamine receptor behavioral responses following chronic cocaine self–administration
- Strengthening the accumbal indirect pathway promotes resilience to compulsive cocaine use
- Imaging glutamate homeostasis in cocaine addiction with the metabotropic glutamate receptor 5 positron emission tomography radiotracer [11C] ABP688 and …
- Effects of dopamine indirect agonists and selective D1-like and D2-like agonists and antagonists on cocaine self–administration and food maintained responding in …
- Suppression of cocaine relapse-like behaviors upon pimavanserin and lorcaserin co-administration
- The mGluR2 positive allosteric modulator BINA decreases cocaine self–administration and cue-induced cocaine-seeking and counteracts cocaine-induced …
- Clavulanic acid enhances glutamate transporter subtype I (GLT-1) expression and decreases reinforcing efficacy of cocaine in mice
- Assessment of reinforcing effects of benztropine analogs and their effects on cocaine self–administration in rats: comparisons with monoamine uptake inhibitors
- Hypocretin/Orexin Receptor 1 Knockdown in GABA or Dopamine Neurons in the Ventral Tegmental Area Differentially Impact Mesolimbic Dopamine and …
- Testing the effects of the GLP-1 receptor agonist exenatide on cocaine self–administration and subjective responses in humans with cocaine use disorder
- BDNF-TrkB controls cocaine-induced dendritic spines in rodent nucleus accumbens dissociated from increases in addictive behaviors
- NOP Receptor Agonist Ro 64-6198 decreases escalation of cocaine self–administration in rats genetically selected for alcohol preference
- κ-Opioid receptor blockade with nor-binaltorphimine modulates cocaine self–administration in drug-naive rats
- Treatment with modafinil and escitalopram, alone and in combination, on cocaine-induced effects: a randomized, double blind, placebo-controlled human laboratory …
- Effect of the glucocorticoid receptor antagonist PT150 on acquisition and escalation of fentanyl self–administration following early-life stress.
- Hypocretin receptor 1 blockade preferentially reduces high effort responding for cocaine without promoting sleep
- Effects of lorcaserin on cocaine and methamphetamine self–administration and reinstatement of responding previously maintained by cocaine in rhesus monkeys
- Attenuation of cocaine-seeking by progesterone treatment in female rats
- Glutamate and reinstatement
- Discriminative stimulus effects of cocaine abuse medications in the rhesus monkey
- Tripping up addiction: the use of psychedelic drugs in the treatment of problematic drug and alcohol use
- Recent advances in understanding nicotinic receptor signaling mechanisms that regulate drug self–administration behavior
- Overdose deaths and acute hepatitis infections among American Indians in North Carolina
- Effect of novel allosteric modulators of metabotropic glutamate receptors on drug self–administration and relapse: a review of preclinical studies and their clinical …
- Effects of the combination of metyrapone and oxazepam on cocaine and food self–administration in rats
- Mirtazapine reduces the expression of cocaine-induced locomotor sensitization in male and female Wistar rats
- Oral administration of the NAALADase inhibitor GPI-5693 attenuates cocaine-induced reinstatement of drug-seeking behavior in rats
- 5-HT1A autoreceptors in the dorsal raphe nucleus convey vulnerability to compulsive cocaine seeking
- Buprenorphine reduces methamphetamine intake and drug seeking behavior via activating nociceptin/orphanin FQ peptide receptor in rats
- PPL-103: A mixed opioid partial agonist with desirable anti-cocaine properties
- Blockade of the serotonin 5-HT2A receptor suppresses cue-evoked reinstatement of cocaine-seeking behavior in a rat self–administration model
- Ventral pallidum DRD3 potentiates a pallido-habenular circuit driving accumbal dopamine release and cocaine seeking
- Glucagon-like peptide-1 receptor activation in the ventral tegmental area attenuates cocaine seeking in rats
- Median and dorsal raphe serotonergic neurons control moderate versus compulsive cocaine intake
- Effects of dopamine transporter selective 3-phenyltropane analogs on locomotor activity, drug discrimination, and cocaine self–administration after oral administration
- Potential role for the hypothalamo–pituitary–adrenal axis in the conditioned reinforcer-induced reinstatement of extinguished cocaine seeking in rats
- Modafinil-cocaine interactions: clinical implications
- Blockade of the serotonin 5-HT2A receptor suppresses cue-evoked reinstatement of cocaine-seeking behavior in a rat self–administration model.
- Factors that Affect Social Hierarchy and the Influence of Social Rank and Menstrual Cycle on cocaine self–administration in Female Cynomolgus Monkeys
- A preliminary, controlled investigation of magnesium L-aspartate hydrochloride for illicit cocaine and opiate use in methadone-maintained patients
- cocaine self–administration, extinction training and drug-induced relapse change metabotropic glutamate mGlu5 receptors expression: Evidence from radioligand …
- The 5-HT2C receptor agonist lorcaserin reduces nicotine self–administration, discrimination, and reinstatement: relationship to feeding behavior and impulse …
- Dual dopamine/serotonin releasers as potential medications for stimulante and alcohol addictions
- Stimulation of medial prefrontal cortex serotonin 2C (5-HT2C) receptors attenuates cocaine-seeking behavior
- Effects of the long-acting monoamine reuptake inhibitor indatraline on cocaine self–administration in rhesus monkeys
- Effects of dopamine and serotonin-releasing agents on methamphetamine discrimination and self–administration in rats
- Effect of adrenalectomy on cocaine facilitation of lateral hypothalamic self-stimulation
- (-)-Stepholidine blocks expression, but not development, of cocaine conditioned place preference in rats
- Decrease of cocaine, but not heroin, self–administration and relapse by the tyrosine kinase inhibitor masitinib in male Sprague Dawley rats
- cocaine and Dysregulated Synaptic Transmission in the Bed Nucleus of the Stria Terminalis
- Behavioral and functional evidence of metabotropic glutamate receptor 2/3 and metabotropic glutamate receptor 5 dysregulation in cocaine-escalated rats: factor in …
- Metabotropic glutamate receptor 5 activity in the nucleus accumbens is required for the maintenance of ethanol self–administration in a rat genetic model of high …
- Buprenorphine as a pharmacotherapy for cocaine abuse: a review of the evidence
- Binge-like sucrose self–administration experience inhibits cocaine and sucrose seeking behavior in offspring
- Effects of cocaine history on postsynaptic GABA receptors on dorsal raphe serotonin neurons in a stress-induced relapse model in rats
- Effect of HD-23, a potent long acting cocaine-analog, on cocaine self–administration in rats
- Inhibition of cocaine and 3, 4-methylenedioxypyrovalerone (MDPV) self–administration by lorcaserin is mediated by 5-HT2C receptors in rats
- Stimulation of dopamine D2/D3 but not D1 receptors in the central amygdala decreases cocaine-seeking behavior
- self‐administration of cocaine and the cocaine analog RTI‐113: Relationship to dopamine transporter occupancy determined by PET neuroimaging in rhesus …
- The novel metabotropic glutamate receptor 2 positive allosteric modulator, AZD8529, decreases nicotine self–administration and relapse in squirrel monkeys
- Effects of escitalopram and imipramine on cocaine reinforcement and drug-seeking behaviors in a rat model of depression
- Intra-Accumbal administration of Mecamylamine Reverses the Effects of Cytisine on the Operant Oral self–administration of Ethanol in Rats
- The mGluR2 Positive Allosteric Modulator BINA Decreases cocaine self–administration and Cue-Induced cocaine-Seeking…
- Behavioral and neurochemical effects of amphetamine analogs that release monoamines in the squirrel monkey
- Effects of isoflurane anesthesia on addictive behaviors in rats
- Interactions between the mGluR2/3 agonist, LY379268, and cocaine on in vivo neurochemistry and behavior in squirrel monkeys
- Environmental enrichment and a selective metabotropic glutamate receptor2/3 (mGluR2/3) agonist suppress amphetamine self–administration: Characterizing …
- Incubation of cocaine cue reactivity associates with neuroadaptations in the cortical serotonin (5-HT) 5-HT2C receptor (5-HT2CR) system
- Nicotine self–administration in the rat: effects of hypocretin antagonists and changes in hypocretin mRNA
- Effects of the mGlu2/3 agonist LY379268 and the mGlu5 antagonist MTEP on ethanol seeking and reinforcement are differentially altered in rats with a history of …
- Genetic and pharmacological evidence that 5-HT2C receptor activation, but not inhibition, affects motivation to feed under a progressive ratio schedule of …
- α2δ-1 signaling in nucleus accumbens is necessary for cocaine-induced relapse
- cocaine-related disorders
- Adult hippocampal neurogenesis as a target for cocaine addiction: a review of recent developments
- Effects of genetic deletion of endogenous opioid system components on the reinstatement of cocaine-seeking behavior in mice
- Imaging glutamate homeostasis in cocaine addiction with the mGluR5 PET radiotracer [11C] ABP688 and Magnetic Resonance Spectroscopy
- Acute treatment with the glucagon-like peptide-1 receptor agonist, liraglutide, reduces cue-and drug-induced fentanyl seeking in rats
- The effects of chronic administration of Buprenorphine on intake of heroin and cocaine in rats: behavioral and neurochemical interactions
- Cebranopadol blocks the escalation of cocaine intake and conditioned reinstatement of cocaine seeking in rats
- Exercise reduces dopamine D1R and increases D2R in rats: implications for addiction
- Prefrontal synaptic markers of cocaine addiction-like behavior in rats
- A new insight into the role of CART in cocaine reward: involvement of CaMKII and inhibitory G-protein coupled receptor signaling
- Impaired extinction of operant cocaine in a genetic mouse model of schizophrenia risk
- Metabotropic glutamate group II receptor activation in the ventrolateral dorsal striatum suppresses incentive motivation for cocaine in rats
- Effects of acute and chronic ketoconazole administration on hypothalamo–pituitary–adrenal axis activity and brain corticotropin-releasing hormone
- Understanding polydrug use: review of heroin and cocaine co‐use
- Flipping the main switch in the central reward system?
- Effects of d-amphetamine and buprenorphine combinations on speedball (cocaine+ heroin) self–administration by rhesus monkeys
- Pair housing does not alter incubation of craving, extinction, and reinstatement after heroin self–administration in female and male rats.
- administration of GABAB receptor positive allosteric modulators inhibit the expression of previously established methamphetamine-induced conditioned place …
- Rats with extended access to cocaine exhibit increased stress reactivity and sensitivity to the anxiolytic-like effects of the mGluR 2/3 agonist LY379268 during …
- Effects of lorcaserin on reinstatement of responding previously maintained by cocaine or remifentanil in rhesus monkeys.
- Nociceptin attenuates the escalation of oxycodone self–administration by normalizing CeA–GABA transmission in highly addicted rats
- Pharmacotherapies for treatment of cocaine abuse: preclinical aspects
- Theta oscillations in rat infralimbic cortex are associated with the inhibition of cocaine seeking during extinction
- The hypodopaminergic state ten years after: transcranial magnetic stimulation as a tool to test the dopamine hypothesis of drug addiction
- BDNF as a therapeutic candidate for cocaine use disorders
- Metabotropic glutamate receptor 2 positive allosteric modulators: closing the gate on drug abuse?
- Multiple faces of BDNF in cocaine addiction
- The long-acting D3 partial agonist MC-25-41 attenuates motivation for cocaine in Sprague-Dawley rats
- Lorcaserin suppresses oxycodone self–administration and relapse vulnerability in rats
- Dual dopamine/serotonin releasers: potential treatment agents for stimulant addiction.
- The dopamine D3 receptor and drug dependence: effects on reward or beyond?
- A protocol for measuring cue reactivity in a rat model of cocaine use disorder
- Serotonin2C receptors and drug addiction: focus on cocaine
- Synergism Between a Serotonin 5-HT2A Receptor (5-HT2AR) Antagonist and 5-HT2CR Agonist Suggests New Pharmacotherapeutics for cocaine Addiction
- Dopamine receptor subtypes in reward and relapse
- NOP-related mechanisms in substance use disorders
- The group II metabotropic glutamate agonist, LY379268, decreases methamphetamine self–administration in rats
- Effects of the combination of metyrapone and oxazepam on cocaine craving and cocaine taking: a double-blind, randomized, placebo-controlled pilot study
- Glial cell line-derived neurotrophic factor mediates the desirable actions of the anti-addiction drug ibogaine against alcohol consumption
- Dual dopamine–5-HT releasers: potential treatment agents for cocaine addiction
- CREB activity in dopamine D1 receptor expressing neurons regulates cocaine-induced behavioral effects
- Medication-related pharmacological manipulations of nicotine self–administration in the rat maintained on fixed-and progressive-ratio schedules of reinforcement
- Glucagon-Like Peptide-1 (GLP-1) and 5-Hydroxytryptamine 2c (5-HT2c) Receptor Agonists in the Ventral Tegmental Area (VTA) Inhibit Ghrelin-Stimulated Appetitive …
- Effects of cebranopadol on cocaine-induced hyperactivity and cocaine pharmacokinetics in rats
- Neuroadaptive changes in metabotropic glutamate mGlu2/3R expression during different phases of cocaine addiction in rats
- The lateral preoptic area: a novel regulator of reward seeking and neuronal activity in the ventral tegmental area
- Epigenetic regulation in substance use disorders
- Topographic transcriptomics of the nucleus accumbens shell: Identification and validation of fatty acid binding protein 5 as target for cocaine addiction
- Metabotropic glutamate group II receptor activation in the dorsal striatum suppresses the motivation for cocaine in rats
- Modeling alcohol self–administration in the human laboratory
- Effects of lorcaserin on oxycodone self–administration and subjective responses in participants with opioid use disorder
- Evidence for a vocal signature in the rat and its reinforcing effects: a key role for the subthalamic nucleus
- The individual and combined effects of phenmetrazine and mgluR2/3 agonist LY379268 on the motivation to self-administer cocaine
- Evaluating the preclinical validity of cannabinoid therapy for the treatment of psychostimulant use disorder
- The serotonin-2C agonist Lorcaserin delays intravenous choice and modifies the subjective and cardiovascular effects of cocaine: A randomized, controlled human …
- D3 Dopamine and Kappa Opioid Receptor Alterations in Human Brain of cocaine‐overdose Victims
- Selective serotonin 5-HT2C receptor activation suppresses the reinforcing efficacy of cocaine and sucrose but differentially affects the incentive-salience value of …
- Pharmacotherapeutics directed at deficiencies associated with cocaine dependence: focus on dopamine, norepinephrine and glutamate
- Understanding comorbid ADHD and cocaine abuse: Consequences of adolescent medication in an animal model
- Effects of 2β-propanoyl-3β-(4-tolyl)-tropane (PTT) on the self–administration of cocaine, heroin, and cocaine/heroin combinations in rats
- New treatments for cocaine dependence: a focused review
- Inhibition of N-acetylated-alpha-linked-acidic dipeptidase (NAALADase) by 2-PMPA attenuates cocaine-induced relapse in rats: a NAAG-mGluR2/3-mediated …
- New medications for drug addiction hiding in glutamatergic neuroplasticity
- Environmental, genetic and epigenetic contributions to cocaine addiction
- Continuous or intermittent cocaine administration: effects of flupenthixol treatment during withdrawal
- Effects of pimavanserin and lorcaserin on alcohol self–administration and reinstatement in male and female rats
- The D3R partial agonist, BP 897, attenuates the discriminative stimulus effects of cocaine and D-amphetamine and is not self-administered
- Neuropsychotoxicity of abused drugs: potential of dextromethorphan and novel neuroprotective analogs of dextromethorphan with improved safety profiles in terms of …
- Effects of lorcaserin (Belviq®) on nicotine-and food-maintained responding in non-human primates
- Assessing addiction vulnerability with different rat strains and place preference procedures: the role of the cocaine and amphetamine-regulated transcript
- Orexin/hypocretin based pharmacotherapies for the treatment of addiction: DORA or SORA?
- Novel approaches to the treatment of cocaine addiction
- Continuous or intermittent cocaine administration: effects of amantadine treatment during withdrawal
- Evaluation of the “pipeline” for development of medications for cocaine use disorder: a review of translational preclinical, human laboratory, and clinical trial research
- Effect of the novel positive allosteric modulator of metabotropic glutamate receptor 2 AZD8529 on incubation of methamphetamine craving after prolonged voluntary …
- Dopamine/serotonin releasers as medications for stimulant addictions
- The group II metabotropic glutamate receptor agonist, LY379268, decreases methamphetamine self–administration in rats
- Functional status of the serotonin 5-HT2C receptor (5-HT2CR) drives interlocked phenotypes that precipitate relapse-like behaviors in cocaine dependence
- Central GLP-1 receptors: Novel molecular targets for cocaine use disorder
- Effects of indatraline and buprenorphine on self–administration of speedball combinations of cocaine and heroin by rhesus monkeys
- Microinjection of CART peptide 55–102 into the nucleus accumbens core inhibits the expression of conditioned hyperactivity in a cocaine-associated environment
- RTI 113, a 3-phenyltropane analog, produces long-lasting cocaine-like discriminative stimulus effects in rats and squirrel monkeys
- Role of mesolimbic ghrelin in the acquisition of cocaine reward
- Effects of the monoamine uptake inhibitors RTI-112 and RTI-113 on cocaine-and food-maintained responding in rhesus monkeys
- The role of the neurokinin-1 receptor in stress-induced reinstatement of alcohol and cocaine seeking
- Sex differences in the neural mechanisms mediating addiction: a new synthesis and hypothesis
- Neurobiological basis for the development of cocaine addiction in females: Role of estradiol
- Behavioral and functional evidence of mGlu2/3 and mGlu5 metabotropic glutamate receptor dysregulation in cocaine-escalated rats: Factor in the transition to …
- Pharmacological approaches to cocaine addiction
- GLP-1 receptor signaling in the laterodorsal tegmental nucleus attenuates cocaine seeking by activating GABAergic circuits that project to the VTA
- cocaine seeking and taking: role of hippocampal dopamine D1-like receptors
- Reward circuitry in addiction
- Lipids and addiction: how sex steroids, prostaglandins, and cannabinoids interact with drugs of abuse
- Metabotropic glutamate receptor ligands as potential therapeutics for addiction
- The Addicted Phenotype: Protein Phosphorylation Status and Dopamine Receptor Responsiveness
- Hypocretin receptor 1 involvement in cocaine-associated behavior: therapeutic potential and novel mechanistic insights
- Clueless about cues: the impact of reward-paired cues on decision making under uncertainty
- The behavioral pharmacology and therapeutic potential of lorcaserin for substance use disorders
- Synthesis of indatraline using a Suzuki cross-coupling reaction and a chemoselective hydrogenation: A versatile approach
- Dopamine D3 receptor partial agonist LS-3-134 attenuates cocaine-motivated behaviors
- Effects of serotonin 2C receptor agonists on the behavioral and neurochemical effects of cocaine in squirrel monkeys
- Feasibility of Exenatide, a GLP-1R Agonist, for Treating cocaine Use Disorder: A Case Series Study
- Characterization of methylphenidate self–administration and reinstatement in the rat
- Varenicline decreases nicotine but not alcohol self–administration in genetically selected Marchigian Sardinian alcohol-preferring (msP) rats
- Confronting the opioid crisis with basic research in neuropharmacology
- Impulsive action induced by amphetamine, cocaine and MK801 is reduced by 5-HT2C receptor stimulation and 5-HT2A receptor blockade
- From obesity to substance abuse: therapeutic opportunities for 5-HT2C receptor agonists
- Effects of the dopamine reuptake inhibitor PTT on reinstatement and on food-and cocaine-maintained responding in rhesus monkeys
- Central injections of noradrenaline induce reinstatement of cocaine seeking and increase c-fos mRNA expression in the extended amygdala
- Medication strategies for the management of cocaine use disorder
- Acute and chronic interactive treatments of serotonin 5HT2C and dopamine D1 receptor systems for decreasing nicotine self–administration in female rats
- The paraventricular thalamic nucleus: a key hub of neural circuits underlying drug addiction
- Lesions of the dorsomedial frontal cortex block sensitization to the positive-reinforcing effects of cocaine
- Learning from lorcaserin: lessons from the negative clinical trial of lorcaserin to treat cocaine use disorder
- Bupropion reduces methamphetamine-induced subjective effects and cue-induced craving
- Evaluation of drug abuse treatment medications: concordance between clinical and preclinical studies
- Baclofen does not alter the reinforcing, subject-rated or cardiovascular effects of intranasal cocaine in humans
- Serotonergic mechanisms in addiction-related memories
- GLP-1 signaling and alcohol-mediated behaviors; preclinical and clinical evidence
- Pharmacokinetic strategies for treatment of drug overdose and addiction
- Effects of buprenorphine/lorcaserin mixtures on preference for heroin, cocaine, or saline over food using a concurrent choice procedure in rhesus monkeys
- Phentermine pretreatment antagonizes the cocaine-induced rise in mesolimbic dopamine
- Effects of co-administration of the GABAB receptor agonist baclofen and a positive allosteric modulator of the GABAB receptor, CGP7930, on the development and …
- Dynamic interactions of ceftriaxone and environmental variables suppress amphetamine seeking
- cocaine induces paradigm-specific changes to the transcriptome within the ventral tegmental area
- CART in energy balance and drug addiction: current insights and mechanisms
- Activation of GLP-1 receptors attenuates oxycodone taking and seeking without compromising the antinociceptive effects of oxycodone in rats
- Neuroplastic alterations in the limbic system following cocaine or alcohol exposure
- The inhibition of cocaine-induced locomotor activity by CART 55-102 is lost after repeated cocaine administration
- Central GLP-1 receptor activation modulates cocaine-evoked phasic dopamine signaling in the nucleus accumbens core
- Mesolimbic dopamine signaling in cocaine addiction
- Agonist replacement therapy for cocaine dependence: a translational review
- Benztropine pretreatment does not affect responses to acute cocaine administration in human volunteers
- Comparative behavioral pharmacology of cocaine and the selective dopamine uptake inhibitor RTI-113 in the squirrel monkey
- Discriminative stimulus effects of dopaminergic agents in rhesus monkeys
- Effects of the 5-HT2C receptor agonist CP809101 in the amygdala on reinstatement of cocaine-seeking behavior and anxiety-like behavior
- Repeated 7-day treatment with the 5-HT2C agonist lorcaserin or the 5-HT2A antagonist pimavanserin alone or in combination fails to reduce cocaine vs food …
- Dose titration with the glucagon-like peptide-1 agonist, liraglutide, reduces cue-and drug-induced heroin seeking in high drug-taking rats
- Metabotropic glutamate 2/3 receptors in the ventral tegmental area and the nucleus accumbens shell are involved in behaviors relating to nicotine dependence
- Effects of single and dual administration of cocaine and ethanol on opioid and ORL1 receptor expression in rat CNS: an autoradiographic study
- CXCL12/CXCR4 signaling in mesocorticolimbic reward pathways: relevance to cocaine reinforcement and relapse
- AMPA receptor synaptic plasticity induced by psychostimulants: the past, present, and therapeutic future
- Design and Synthesis of Systemically Active Metabotropic Glutamate Subtype-2 and -3 (mGlu2/3) Receptor Positive Allosteric Modulators (PAMs): Pharmacological …
- Glucagon-like peptide-1 receptor agonist, exendin-4, reduces reinstatement of heroin seeking behavior in rats
- Attenuation of cocaine-induced reinstatement of drug seeking in squirrel monkeys by direct and indirect activation of 5-HT2C receptors
- Lorcaserin decreases the reinforcing effects of heroin, but not food, in rhesus monkeys
- Metabotropic glutamate receptor 7 (mGluR7) as a target for the treatment of psychostimulant dependence
- Clinical potential of a rationally engineered enzyme for treatment of cocaine dependence: Long-lasting blocking of the psychostimulant, discriminative stimulus, and …
- Dopamine transport inhibitors based on GBR12909 and benztropine as potential medications to treat cocaine addiction
- The dopamine D3 receptor: a therapeutic target for the treatment of neuropsychiatric disorders
- Oxycodone self–administration and withdrawal behaviors in male and female Wistar rats
- Increases in compulsivity, inflammation, and neural injury in HIV transgenic rats with escalated methamphetamine self–administration under extended-access …
- Effects of the serotonin 2C receptor agonist WAY163909 on the abuse-related effects and mesolimbic dopamine neurochemistry induced by abused stimulants in …
- Metabotropic glutamate receptors 2 and 3 as targets for treating nicotine addiction
- Substituted 1-Phenyl-3-(pyridin-2-yl)urea Negative Allosteric Modulators of mGlu5: Discovery of a New Tool Compound VU0463841 with Activity in Rat Models of …
- Group II metabotropic glutamate receptors (mGlu2/3) in drug addiction
- The influence of stress on the transition from drug use to addiction
- Alcohol-mediated behaviours and the gut-brain axis; with focus on glucagon-like peptide-1
- self–administration of drugs of abuse
- Considerations in the evaluation of potential efficacy of medications for alcohol and drug use disorders: an editorial
- Serotonin2C receptors in the medial prefrontal cortex facilitate cocaine-induced dopamine release in the rat nucleus accumbens
- GIRK3 gates activation of the mesolimbic dopaminergic pathway by ethanol
- Efficacy of buspirone for attenuating cocaine and methamphetamine reinstatement in rats
- Glucagon-like peptide 1 receptor activation regulates cocaine actions and dopamine homeostasis in the lateral septum by decreasing arachidonic acid levels
- Effects of the mGluR2/3 receptor agonist LY379268 on the reinforcing strength of cocaine in rhesus monkeys
- Antagonizing 5-HT2A receptors with M100907 and stimulating 5-HT2C receptors with Ro60-0175 blocks cocaine-induced locomotion and zif268 mRNA expression in …
- Sex differences in selecting between food and cocaine reinforcement are mediated by estrogen
- Intermittent intake of rapid cocaine injections promotes robust psychomotor sensitization, increased incentive motivation for the drug and mGlu2/3 receptor …
- Role of the glutamatergic system in nicotine dependence: implications for the discovery and development of new pharmacological smoking cessation therapies
- Reduced ethanol consumption and preference in cocaine‐and amphetamine‐regulated transcript (CART) knockout mice
- A single cocaine administration alters dendritic spine morphology and impairs glutamate receptor synaptic retention in the medial prefrontal cortex of adolescent rats
- Using glutamate homeostasis as a target for treating addictive disorders
- rTMS reduces psychopathological burden and cocaine consumption in treatment-seeking subjects with cocaine use disorder: an open label, feasibility study
- Contributions of serotonin in addiction vulnerability
- Transcriptional and epigenetic regulation of reward circuitry in drug addiction
- Serotonin and Reward-Related Behavior: Focus on 5-HT2C Receptors
- mGlu5 receptors: neuroanatomy, pharmacology, and role in drug addiction
- Exercise and substance abuse
- Glutamate neurotransmission in the course of cocaine addiction
- Non-invasive brain stimulation in substance use disorders: implications for dissemination to clinical settings
- Street-Wise Crack Research: Like earlier students of tribal culture, modern ethnographers live and work with” crack families” in the toughest neighborhoods of New …
- Repeated cocaine exposure prior to fear conditioning induces persistency of PTSD-like symptoms and enhancement of hippocampal and amygdala cell density in …
- The GABA-B antagonist 2-hydroxysaclofen reverses the effects of baclofen on the discriminative stimulus effects of D-amphetamine in the conditioned taste aversion …
- Heightened cocaine-seeking in male rats associates with a distinct transcriptomic profile in the medial prefrontal cortex
- Opposing Spatially Segregated Function of Endogenous GDNF-RET Signaling in cocaine Addiction
- CART peptide in the nucleus accumbens shell acts downstream to dopamine and mediates the reward and reinforcement actions of morphine
- Intermittent access training produces greater motivation for a non-drug reinforcer than long access training
- Critical involvement of 5-HT2C receptor function in amphetamine-induced 50-kHz ultrasonic vocalizations in rats
- Ventral tegmental area afferents and drug-dependent behaviors
- Differential effects of intra-ventral tegmental area ghrelin and glucagon-like peptide-1 on the stimulatory action of D-amphetamine and cocaine-induced ethanol intake …
- Trace Amine-Associated Receptor 1 and cocaine Abuse
- Serotonin receptors as potential targets for modulation of nicotine use and dependence
- Lipid transmitter signaling as a new target for treatment of cocaine addiction: new roles for acylethanolamides and lysophosphatidic acid
- Intraaccumbens baclofen selectively enhances feeding behavior in the rat
- CART peptides: regulators of body weight, reward and other functions
- The combination of metyrapone and oxazepam for the treatment of cocaine and other drug addictions
- Cebranopadol, a novel long-acting opioid agonist with low abuse liability, to treat opioid use disorder: Preclinical evidence of efficacy
- The dopamine D3 receptor partial agonist CJB 090 inhibits the discriminative stimulus but not the reinforcing or priming effects of cocaine in squirrel monkeys
- Imidazenil, a positive allosteric GABAA receptor modulator, inhibits the effects of cocaine on locomotor activity and extracellular dopamine in the nucleus accumbens …
- cocaine use disorder: a look at metabotropic glutamate receptors and glutamate transporters
- Endocannabinoid influence in drug reinforcement, dependence and addiction-related behaviors
- HPA axis-interaction with behavioral systems
- The role of the serotonin transporter in prefrontal cortex glutamatergic signaling following
- Therapeutic Potential of 5-HT2C Receptor Agonists for Addictive Disorders
- From bench to bedside: mGluR2 positive allosteric modulators as medications to treat substance use disorders
- Anti-relapse medications: preclinical models for drug addiction treatment
- Interactions of glutamatergic neurotransmission and brain-derived neurotrophic factor in the regulation of behaviors after nicotine administration
- A novel dual agonist of glucagon-like peptide-1 receptors and neuropeptide Y2 receptors attenuates fentanyl taking and seeking in male rats
- Accumbens volumes are reduced among crack-cocaine users
- Medication take-home doses and contingency management.
- Acute Glucagon-Like Peptide-1 Receptor Agonist Liraglutide Prevents Cue-, Stress-and Drug-Induced Heroin Seeking in Rats
- Neurobiology of substance use disorders
- Sex differences and addiction
- Neurochemical adaptations and cocaine dependence
- Antagonism of metabotropic glutamate 1 receptors attenuates behavioral effects of cocaine and methamphetamine in squirrel monkeys
- Activation of the amylin pathway modulates cocaine-induced activation of the mesolimbic dopamine system in male mice
- Ethical issues raised by proposals to treat addiction using deep brain stimulation
- A functional inhibitory role of habenular glucagon-like peptide-1 (GLP-1) in forebrain reward signaling
- BETHANY R. BROOKSHIRE
- H3K4 dimethylation at FosB promoter in the striatum of chronic stressed rats promotes morphine-induced conditioned place preference
- The role of neuropeptide CART in the lateral hypothalamic-ventral tegmental area (LH-VTA) circuit in motivation
- Interaction between noradrenaline and corticotrophin-releasing factor in the reinstatement of cocaine seeking in the rat
- Mecamylamine: new therapeutic uses and toxicity/risk profile
- Interaction between cocaine use and sleep behavior: a comprehensive review of cocaine‘s disrupting influence on sleep behavior and sleep disruptions …
- The neural basis of addiction: a pathology of motivation and choice
- Biphasic reward effects are characteristic of both lorcaserin and drugs of abuse: implications for treatment of substance use disorders
- Introduction to the Special Issue:“Making orexin-based therapies for addiction a reality: What are the steps from here?”
- Drug dependence as a disorder of neural plasticity: focus on dopamine and glutamate
- The hypothalamic-pituitary-adrenal axis and addiction
- The role of 5-HT2a/2c receptors in nociception and opioid antinociception: A review of the preclinical literature
- Neurosteroids and Addictive Pathology
- Impact of social stress in addiction to psychostimulants: what we know from animal models
- A review on the role of metabotropic glutamate receptors in neuroplasticity following psychostimulant use disorder
- Differential effects of blockade of dopamine D1-family receptors in nucleus accumbens core or shell on reinstatement of heroin seeking induced by contextual and …
- Appetite suppressants as agonist substitution therapies for stimulant dependence
- Abstract# 155: Individualized connectivity between rTMS targets and the subgenual cingulate is unrelated to antidepressant response
- γ-Aminobutyric acid mimetic drugs differentially inhibit the dopaminergic response to cocaine
- NOP agonist action of cebranopadol counteracts its liability to promote physical dependence
- cocaine-and amphetamine-regulated transcript (CART): a multifaceted neuropeptide
- Nr4a1 suppresses cocaine-induced behavior via epigenetic regulation of homeostatic target genes
- Recent developments in the behavioural and pharmacological enhancement of extinction of drug seeking
- Clinical pharmacology and toxicology of cocaine
- 3, 4-methylenedioxypyrovalerone high-responder phenotype as a tool to evaluate candidate medications for stimulant use disorder
- Action of cocaine involves depletion of dopaminergic and serotonergic storage vesicles
- Context-induced relapse to drug seeking: a review
- Critical assessment of how to study addiction and its treatment: human and non-human animal models
- The Pharmacology of an Agonist Medication to Treat Stimulant Use Disorder
- PYY3-36 infused systemically or directly into the VTA attenuates fentanyl seeking in male rats
- Abstract# 156: Functional connectivity changes with targeted rTMS of the dorsal attention network in TBI-associated depression
- Regulation of dynorphin gene expression by κ-opioid agonist treatment
- Can GLP-1 be a target for reward system related disorders? A qualitative synthesis and systematic review analysis of studies on palatable food, drugs of …
- Stress and relapse to cocaine seeking in the rat: Effects of post-stress delay periods and influence of environmental context
- Possible mechanisms underlying the effects of glucagon-like peptide-1 receptor agonist on cocaine use disorder
- Glucagon-like peptide-1 receptor agonist treatment does not reduce abuse-related effects of opioid drugs
- Cross-talk between the HPA axis and addiction-related regions in stressful situations
- CART peptides and drugs of abuse: a review of recent progress
- Compulsive methamphetamine taking in the presence of punishment is associated with increased oxytocin expression in the nucleus accumbens of rats
- Dopamine receptor subtype agonists and feeding behavior
- Type 4 phosphodiesterases and drug conditioned reward in mice
- The role of noradrenaline and 5-hydroxytryptamine in yohimbine-induced increases in alcohol-seeking in rats
- Anticocaine catalytic antibodies have no affinity for RTI compounds: implications for treatment
- Maintenance of conditioned place preferences and aversion in C57BL6 mice: effects of repeated and drug state testing
- cocaine and inhibition of nitric oxide synthesis produce opioid-mediated antinociception
- Alpha-2 Adrenergic Receptors in Alcohol self–administration and Relapse in Rats: Role of Alcohol Dependence and Sex
- 6.3 NEUROCHEMICAL ADAPTATIONS AND cocaine DEPENDENCE
- Evidence-based treatments of addiction
- Neurochemical mechanisms of phentermine and fenfluramine: therapeutic and adverse effects
- Cannabidiol prevents several of the behavioral alterations related to cocaine addiction in mice
- Intermittent theta burst stimulation of the prefrontal cortex in cocaine use disorder: a pilot study
- Effects of metabotropic glutamate receptor ligands on male sexual behavior in rats
- Extended access to oxycodone self–administration produces hyperalgesia and irritability-like behavior in male and female rats.
- Pre-clinical anti-addictive and side-effect profiles of novel kappa-opioid agonists
- Neurotrophins in the ventral tegmental area: Role in social stress, mood disorders and drug abuse
- Cortical and subthalamic circuits in the regulation of addiction-like behaviors
- Nicotinic receptors differentially modulate the induction and expression of behavioral sensitization to methylphenidate in rats
- Effects of a single dose of baclofen on self-reported subjective effects and tobacco smoking
- Hunger and satiety gauge reward sensitivity
- G protein‐coupled receptor modulation of striatal dopamine transmission: Implications for psychoactive drug effects
- Neurobehavioral effects of environmental enrichment and drug abuse vulnerability: An updated review
- Environmental Enrichment and the Effects on Drug Abuse Vulnerability: The Last Ten Years
- Intraperitoneal administration of CART 55–102 inhibits psychostimulant-induced locomotion
- Gut-brain axis and addictive disorders: A review with focus on alcohol and drugs of abuse
- The relationship between feeding and drug-seeking behaviors
- Acute Glucagon-Like Peptide-1 Receptor Agonist Liraglutide Prevents Drug-Induced Heroin Seeking in Rats
- G protein-coupled receptor modulation of striatal dopamine transmission: Implications for substance use disorders
- Increases in compulsivity, inflammation, and neural injury in HIV transgenic rats with escalated methamphetamine self–administration under extended-access …
- Endogenous glucagon-like peptide-1 receptor signaling in the nucleus tractus solitarius is required for food intake control
- Microinjection of the mGluR2/3 agonist, LY379268, into the nucleus accumbens attenuates extinction latencies and the reinstatement of morphine-induced …
- 5 CHAPTER Neurochemical Adaptations and cocaine Dependence
- Effects of linagliptin on morphine dependence in larval zebrafish ()
- Drugs currently in Phase II clinical trials for cocaine addiction
- Functional profile of systemic and intrathecal cebranopadol in nonhuman primates
- Priming with BTCP, a dopamine reuptake blocker, reinstates cocaine-seeking and enhances cocaine cue-induced reinstatement
- cocaine, β-Endorphin, and δ-Opioid Receptors
- Pioglitazone attenuates the opioid withdrawal and vulnerability to relapse to heroin seeking in rodents
- Novel Pharmacological Agents for the Treatment of cocaine Use Disorder
- Role of melanin-concentrating hormone in drug use disorders
- The neurobiology of addiction
- Evidence-based treatments of addiction.
- The winding road to relapse: forging a new understanding of cue-induced reinstatement models and their associated neural mechanisms
- Escalated (Dependent) Oxycodone self–administration Is Associated with Cognitive Impairment and Transcriptional Evidence of Neurodegeneration in …
- Reward loss and addiction: Opportunities for cross-pollination
- Environmental enrichment alleviates cognitive and psychomotor alterations and increases adult hippocampal neurogenesis in cocaine withdrawn mice
- Hippocampal-dependent inhibitory learning and memory processes in the control of eating and drug taking
- PICK1-deficient mice exhibit impaired response to cocaine and dysregulated dopamine homeostasis
- Stressing the other paraventricular nucleus
- Clinical and functional connectivity outcomes of 5-Hz repetitive transcranial magnetic stimulation as an add-on treatment in cocaine use disorder: a double-blind …
- Abuse liability assessment for biologic drugs–All molecules are not created equal
- The selective dopamine D3 receptor antagonist SB-277011-A attenuates ethanol consumption in ethanol preferring (P) and non-preferring (NP) rats
- Hennepin County Medical Center and University of Minnesota
- Neurobiology of stimulants.
- Mirtazapine, and mirtazapine-like compounds as possible pharmacotherapy for substance abuse disorders: evidence from the bench and the bedside
- Prenatal buprenorphine exposure and sexually dimorphic nonreproductive behaviors in rats
- Traditional medicine in the treatment of drug addiction
- cocaine-and amphetamine-regulated transcript in the nucleus accumbens shell attenuates context-induced reinstatement of alcohol seeking.
- Vulnerability to addiction
- The role of hypocretin in driving arousal and goal-oriented behaviors
- Sleep is increased by liraglutide, a glucagon-like peptide-1 receptor agonist, in rats
- Abuse potential of pregabalin: a systematic review
- Cebranopadol as a Novel Promising Agent for the Treatment of Pain
- Neuroinflammatory response in reward-associated psychostimulants and opioids: a review
- Role of dopamine D1-family receptors in dorsolateral striatum in context-induced reinstatement of heroin seeking in rats
- Efficacy of high-frequency (15 Hz) repetitive transcranial magnetic stimulation (rTMS) of the left premotor cortex/dorsolateral prefrontal cortex in decreasing cocaine …
- Sex-dependent divergence in the effects of GLP-1 agonist exendin-4 on alcohol reinforcement and reinstatement in C57BL/6J mice
- cocaine and amphetamine related transcript (CART) inhibits context induced reinstatement of reward seeking.
- The Potential Role of Dopaminergic Neuromodulation in Adolescence
- Effects of a glucagon-like peptide-1 analog on appetitive and consummatory behavior for rewarding and aversive gustatory stimuli in rats
- RTI-76, an irreversible inhibitor of dopamine transporter binding, increases locomotor activity in the rat at high doses
- Targeting mGluR2/3 for treatment of neurodegenerative and neuropsychiatric diseases
- Neuronal nicotinic acetylcholine receptors in reward and addiction
- The therapeutic potential of glucagon-like peptide-1 for persons with addictions based on findings from preclinical and clinical studies
- Activity-dependent epigenetic remodeling in cocaine use disorder
- Norepinephrine as a Therapeutic Target for cocaine Use Disorder
- The role of the metabotropic glutamate 5 and adenosine 2A receptors in methamphetamine addiction
- Repeated cocaine exposure dysregulates BDNF expression and signaling in the mesocorticolimbic pathway of the adolescent rat
- The neurosteroid dehydroepiandrosterone sulfate, but not androsterone, enhances the antidepressant effect of cocaine examined in the forced swim test—possible …
- New directions in medication-facilitated behavioral treatment for substance use disorders
- Glutamatergic transmission in drug reward: implications for drug addiction
- Neurorobiology and evidence-based biological treatments for substance abuse disorders
- #VALUE!
- Treatment of co-occurring alcohol and other drug use disorders
- Evaluation of the conditioned reinforcing effects of phentermine and fenfluramine in the rat: concordance with clinical studies
- Brain region specific glucagon-like peptide-1 receptors regulate alcohol-induced behaviors in rodents
- The Gut-Brain Axis and Addictions: A New Narrative
- How addictive are gabapentin and pregabalin? A systematic review
- Attenuation of morphine dependence and withdrawal in rats by venlafaxine, a serotonin and noradrenaline reuptake inhibitor
- Nociceptin/orphanin FQ receptor ligands and translational challenges: focus on cebranopadol as an innovative analgesic
- Preclinical Evidence for Intersectional Impacts of HIV and cocaine Use Disorders on Behavior and Neuroimmune Function
- Pharmacological and genetic interventions in serotonin (5-HT) 2C receptors to alter drug abuse and dependence processes
- Effect of the novel positive allosteric modulator of mGluR2 AZD8529 on incubation of methamphetamine craving after prolonged voluntary abstinence in a rat …
- Linagliptin, a selective dipeptidyl peptidase-4 inhibitor, reduces physical and behavioral effects of morphine withdrawal
- Contribution of a mesocorticolimbic subcircuit to drug context-induced reinstatement of cocaine-seeking behavior in rats
- Inhibitory actions of mGlu4 receptor ligands on cocaine-, but not nicotine-, induced sensitizing and conditioning locomotor responses in rats
- Metabotropic glutamate receptors as targets for the treatment of drug and alcohol dependence
- Depletion of serotonin decreases the effects of the kappa-opioid receptor agonist U-69593 on cocaine-stimulated activity
- Brain site-specific inhibitory effects of the GLP-1 analogue exendin-4 on alcohol intake and operant responding for palatable food
- Regulation of cocaine-induced behaviors and anxiety produced by cocaine withdrawal through the serotonin 2C (5-HT2C) receptor
- The endogenous opioid system in cocaine addiction: what lessons have opioid peptide and receptor knockout mice taught us?
- 2006 NATHAN B. EDDY MEMORIAL AWARD LECTURE
- Role of dorsal medial prefrontal cortex dopamine D1-family receptors in relapse to high-fat food seeking induced by the anxiogenic drug yohimbine
- Exercise as treatment for substance abuse
- Inhibition of experimental visceral pain in rodents by cebranopadol
- Lesions of the ventral tegmental area disrupt drug-induced appetite stimulating effects but spare reward comparison
- Addiction III: From mouse to man
- GRADUATE STUDENTS/POSTDOCTORAL FELLOWS
- Transcranial magnetic stimulation for the treatment of cocaine addiction: A systematic review
- The serotonin 5-HT2C receptor and the non-addictive nature of classic hallucinogens
- Muscarinic receptors: their roles in disorders of the central nervous system and potential as therapeutic targets
- Abstract# 154: Epidural Anesthesia to Effectively Manage Pain and Facilitate Rehabilitation in a Pediatric Case of CRPS
- Role of nociceptin/orphanin FQ-NOP receptor system in the regulation of stress-related disorders
- Role of GABAA receptors in dorsal raphe nucleus in stress-induced reinstatement of morphine-conditioned place preference in rats
- Anhedonic-like behavior and BDNF dysregulation following a single injection of cocaine during adolescence
- Dopamine receptor partial agonists and addiction
- Preference for palatable food, impulsivity, and relation to drug addiction in rats
- The Neuropsychoendocrinology of Substance Use Disorders
- Acute effects of intravenous cocaine administration on serum concentrations of ghrelin, amylin, glucagon-like peptide-1, insulin, leptin and peptide YY and …
- Choice between delayed food and immediate opioids in rats: treatment effects and individual differences
- Gut peptide regulation of food intake–evidence for the modulation of hedonic feeding
- Stress, anxiety, and cocaine abuse
- Increased temporal discounting after chronic stress in CHL1-deficient mice is reversed by 5-HT2C agonist Ro 60-0175
- rTMS-induced changes in glutamatergic and dopaminergic systems: relevance to cocaine and methamphetamine use disorders
- Activation of ventral tegmental area 5-HT2C receptors reduces incentive motivation
- A double-blind, placebo-controlled trial of tiagabine for the treatment of cocaine dependence
- Crosstalk between opioid and anti-opioid systems: An overview and its possible therapeutic significance
- Serotonergic systems in the pathophysiology of ethanol dependence: relevance to clinical alcoholism
- Saccharin preference in rats: relation to impulsivity and drug abuse
- Cebranopadol: A novel first-in-class potent analgesic acting via NOP and opioid receptors
- Pharmacological modulation of 5-HT2C receptor activity produces bidirectional changes in locomotor activity, responding for a conditioned reinforcer, and …
- Serotonin2C receptor stimulation inhibits cocaine-induced Fos expression and DARPP-32 phosphorylation in the rat striatum independently of dopamine outflow
- An overview of appetite-regulatory peptides in addiction processes; from bench to bed side
- Activation of group II metabotropic glutamate receptors inhibits the discriminative stimulus effects of alcohol via selective activity within the amygdala
- Allosteric modulation of metabotropic glutamate receptors
- Reinstatement of cocaine seeking in rats by the pharmacological stressors, corticotropin-releasing factor and yohimbine: role for D1/5 dopamine receptors
- Nicotine regulates cocaine‐amphetamine‐Regulated Transcript (Cart) in the mesocorticolimbic system
- Metabotropic glutamate receptors: from the workbench to the bedside
- Kappa opioid receptor activation in the nucleus accumbens inhibits glutamate and GABA release through different mechanisms
- Metabotropic glutamate 2/3 receptors in the ventral tegmental area and the nucleus accumbens
- Development of allosteric modulators of GPCRs for treatment of CNS disorders
- Contributions of non-human primates to the understanding of cocaine addiction
- Amantadine treatment for cocaine-dependent patients with severe withdrawal symptoms
- DeepREAL: a deep learning powered multi-scale modeling framework for predicting out-of-distribution ligand-induced GPCR activity
- The roles of cannabinoid and dopamine receptor systems in neural emotional learning circuits: implications for schizophrenia and addiction
- Involvement of noradrenergic neurotransmission in the stress-but not cocaine-induced reinstatement of extinguished cocaine-induced conditioned place …
- The effect of the mGlu8 receptor agonist,(S)-3, 4-DCPG on acquisition and expression of morphine-induced conditioned place preference in male rats
- Transcranial magnetic stimulation: a review about its efficacy in the treatment of alcohol, tobacco and cocaine addiction
- The lateral preoptic area regulates the ventral tegmental area and drives reinforcement and aversion
- Misuse and abuse of pregabalin and gabapentin: cause for concern?
- Pharmacology of metabotropic glutamate receptor allosteric modulators: structural basis and therapeutic potential for CNS disorders
- Progress report from the testing program for stimulant and depressant drugs (1998)
- Regional influence of cocaine on evoked dopamine release in the nucleus accumbens core: A role for the caudal brainstem
- Yohimbine, but not footshock stress, reinstates heroin seeking in the presence of a discriminative, drug-predictive cue
- A critical role of nucleus accumbens dopamine D1-family receptors in renewal of alcohol seeking after punishment-imposed abstinence.
- The orexin 1 receptor modulates kappa opioid receptor function via a JNK-dependent mechanism
- Drug addiction co-morbidity with alcohol: Neurobiological insights
- LSD1-BDNF activity in lateral hypothalamus-medial forebrain bundle area is essential for reward seeking behavior
- Long-term outcome of repetitive transcranial magnetic stimulation in a large cohort of patients with cocaine-use disorder: an observational study
- Age-and sex-specific effects of amphetamines on cognition and serotonin in the orbitofrontal cortex
- Metabotropic glutamate receptor 3 is associated with heroin dependence but not depression or schizophrenia in a Chinese population
- Action-outcome expectancies require orbitofrontal neurotrophin systems in naïve and cocaine-exposed mice
- Regulation of cocaine-induced reinstatement by group II metabotropic glutamate receptors in the ventral tegmental area
- The involvement of nicotinic cholinergic receptors in drug abuse
- Neural basis of pleasure and reward
- Lack of correlation between the activity of the mesolimbic dopaminergic system and the rewarding properties of pregabalin in mouse
- 2002 Medicinal Chemistry Division Award address: monoamine transporters and opioid receptors. Targets for addiction therapy
- Individual differences in the improvement of cocaine-induced place preference response by the 5-HT2C receptor antagonist SB242084 in rats
- Regional Effects of cocaine on Phasic Dopamine Release in the Nucleus Accumbens: A Role for the Hindbrain
- Modafinil blocks reinstatement of extinguished opiate-seeking in rats: mediation by a glutamate mechanism
- cocaine and amphetamine related transcript (CART) inhibits context induced reinstatement of reward seeking
- Glucagon-like peptide-1 and alcohol-mediated behaviors in rodents
- Cannabinoid type-2 receptors: An emerging target for regulating schizophrenia-relevant brain circuits
- Cigarette smoking and short-term addiction treatment outcome
- Influence of local and circuit-wide modulation of the mesocorticolimbic reward system on the reinstatement of cocaine seeking
- Blockade of nucleus accumbens 5-HT2A and 5-HT2C receptors prevents the expression of cocaine-induced behavioral and neurochemical sensitization in …
- SYMPOSIUM XI CPDD: CHEMISTRY TO PHARMACOLGY: DRUGS AND DEPENDENCE
- Differences in the structure of drinking, cart expression and dopamine turnover between polydipsic and non polydipsic rats in the quinpirole model of psychotic …
- Brain and cognition for addiction medicine: From prevention to recovery neural substrates for treatment of psychostimulant-induced cognitive deficits
- Drugs currently in Phase II clinical trial for cocaine addiction
- Effect of cocaine and Ethanol on the glutamatergic system
- Regulation of cocaine-induced Behaviors and Anxiety Produced by cocaine Withdrawal through the Serotonin (2C) Receptor
- The NOP receptor system in neurological and psychiatric disorders: discrepancies, peculiarities and clinical progress in developing targeted therapies
- Intracerebroventricular CART peptide reduces food intake and alters motor behavior at a hindbrain site
- Attenuation of cocaine-induced conditioned locomotion is associated with altered expression of hippocampal glutamate receptors in mice lacking LPA1 receptors
- Brain opioid mechanisms in amphetamine induced behaviours
- κ2 opioid receptors in limbic areas of the human brain are upregulated by cocaine in fatal overdose victims
- Cigarette smoking, type 2 diabetes mellitus, and glucagon-like peptide-1 receptor agonists as a potential treatment for smokers with diabetes: An integrative review
- Development of a highly efficient long-acting cocaine hydrolase entity to accelerate cocaine metabolism
- Identifying roles for peptidergic signaling in mice
- A single cocaine administration alters dendritic spine morphology and impairs glutamate
- The role of serotonin in memory: interactions with neurotransmitters and downstream signaling
- Turn the next page: Envisioning the future of addiction therapeutics.
- cocaine‐and amphetamine‐regulated transcript peptide in the nucleus accumbens shell inhibits cocaine‐induced locomotor sensitization to transient over …
- The role of dopamine receptors and inhibitory G proteins in stimulant and opioid reinforcement
- The effect of glucagon-like peptide-1 (GLP-1) receptor agonists on substance use disorder (SUD)-related behavioural effects of drugs and alcohol: A systematic review
- Evidence for the involvement of dopamine transporters in behavioral stimulant effects of modafinil
- Targeting the 5-HT2C receptor in biological context and the current state of 5-HT2C receptor ligand development
- Glutamatergic transmission in drug reward: implications for drug addiction (2015)
- Insulin and fluoxetine produce opposite actions on lateral septal nucleus–infralimbic region connection responsivity
- Clinical Off-Label Use of Deep Transcranial Magnetic Stimulation in Psychiatric Conditions
- Effects of 5-HT2C receptor stimulation in male mice on behaviour and Fos expression: Feeding, reward and impulsivity
- The glucagon-like peptide 1 receptor agonist Exendin-4 decreases relapse-like drinking in socially housed mice
- Gender does not matter: add-on repetitive transcranial magnetic stimulation treatment for female methamphetamine dependents
- Nociceptin/orphanin FQ receptors modulate the discriminative stimulus effects of oxycodone in C57BL/6 mice
- Neuropsychopharmacological understanding for therapeutic application of morphinans
- Fluoxetine treatment of depressive disorders in methadone-maintained opioid addicts
- Glucagon-like peptide-1 receptors within the nucleus of the solitary tract regulate alcohol-mediated behaviors in rodents
- The Role of the Serotonin 2 Family of Receptors in cocaine-elicited and cocaine-conditioned Behaviors
- Innate cocaine-seeking vulnerability arising from loss of serotonin-mediated aversive effects of cocaine in rats
- The role of neuroscience in drug policy: promises and prospects
- GLP-1 and weight loss: unraveling the diverse neural circuitry
- Upregulation of nerve growth factor in central amygdala increases sensitivity to opioid reward
- Dopamine D3 receptor ligands: a patent review (2014–2020)
- CART peptides regulate psychostimulants and may be endogenous antidepressants
- The neuronal circuitry underlying the reinstatement of cocaine-seeking behavior in rats
- Neurobiology of cataplexy
- History use, and basic pharmacology of stimulants
- Expression and distribution of neuropeptide-expressing cells throughout the rodent paraventricular nucleus of the thalamus
- Serotonergic modulation of the behavioral and neurochemical effects of cocaine
- A mechanistic overview of approaches for the treatment of psychostimulant dependence
- Monoamine transporters and psychostimulant drugs
- Arc and homer 1a expression following intravenous administration of heroin and cocaine: a novel application of the catFISH technique
- Preclinical Models of Relapse to Psychostimulants Induced by Environmental Stimuli
- Gabapentinoid use disorder: Update for clinicians
- Antagonism of metabotropic glutamate group II receptors in the potential treatment of neurological and neuropsychiatric disorders
- Transcranial Magnetic Stimulation as a Tool to Promote Smoking Cessation and Decrease Drug and Alcohol Use
- Role of impulsivity and reward in the anti-obesity actions of 5-HT2C receptor agonists
- Methamphetamine Induces TET1- and TET3-Dependent DNA Hydroxymethylation of Crh and Avp Genes in the Rat Nucleus Accumbens
- Neuronal nicotinic receptors as brain targets for pharmacotherapy of drug addiction
- A Review of the Behavioral Effects of Serotonin (5-HT) 1B, 2A, and 2C Receptors on Psychostimulant Addiction-Like Behaviors in Animals
- The Role of Brain Reward Systems in Pathological Behavior: Cellular and molecular deconstruction of striatal adaptations
- CART peptide regulates psychostimulant-induced activity and exhibits a rate dependency
- Identifying Novel Roles for Peptidergic Signaling in Mice
- Deep TMS H7 coil: features, applications & future
- Transcranial magnetic stimulation of the medial prefrontal cortex for psychiatric disorders: a systematic review
- Chronic physical and vicarious psychosocial stress alter fentanyl consumption and nucleus accumbens Rho GTPases in male and female C57BL/6 mice
- Cue-elicited functional connectivity of the periaqueductal gray and tonic cocaine craving
- Mechanisms and treatments of drug consumption: A preclinical exploration in harm reducing pharmacotherapies for substance use disorders
- The role of stress in psychostimulant addiction: treatment approaches based on animal models
- Chronic phenmetrazine treatment promotes D2 dopaminergic and α2-adrenergic receptor desensitization and alters phosphorylation of signaling proteins and local …
- Voluntary cocaine or sugar intake induce neuroadaptations of the endocannabinoid system in reward-related brain regions
- Non-invasive brain stimulation modalities for the treatment and prevention of opioid use disorder: a systematic review of the literature
- Mechanism of Action of the Glucagon-like Peptide-1 analog Exendin-4 in the Reward System–A Preclinical Study in the Drug Addiction Field
- Systemic administration of anorexic gut peptide hormones impairs hedonic-driven sucrose consumption in mice
- Abstinence-induced nicotine seeking relays on a persistent hypoglutamatergic state within the amygdalo-striatal neurocircuitry
- Binge-like palatable food intake in rats reduces preproglucagon in the nucleus tractus solitarius
- Lateral Habenula 5-HT2C Receptor Function Is Altered by Acute and Chronic Nicotine Exposures
- Psychostimulants: basic and clinical pharmacology
- Silvia S. Martins, MD, PhD Julian Santaella-Tenorio, MSc
- Increase in cocaine-and amphetamine-regulated transcript (CART) in specific areas of the mouse brain by acute caffeine administration
- Immune signaling as a node of interaction between systems that sex-specifically develop during puberty and adolescence
- Rewiring the addicted brain: circuits-based treatment for addiction
- Intra-accumbal administration of shRNAs against CART peptides cause increases in body weight and cocaine-induced locomotor activity in rats
- Yohimbine depresses excitatory transmission in BNST and impairs extinction of cocaine place preference through orexin-dependent, norepinephrine …
- The addicted brain: why we abuse drugs, alcohol, and nicotine
- Role of serotonin in the regulation of the dynorphinergic system by a κ-opioid agonist and cocaine treatment in rat CNS
- Locomotor stimulant effects of novel phenyltropanes in the mouse
- cocaine and amphetamine-regulated transcript-containing neurons in the nucleus accumbens project to the ventral pallidum in the rat and may inhibit cocaine …
- Genome-edited skin epidermal stem cells protect mice from cocaine-seeking behaviour and cocaine overdose
- Director’s Report
- Clinical investigations of compounds targeting metabotropic glutamate receptors
- Substance Use Disorders and the Behavioral Effects of Novel and Existing Compounds
- The role of linagliptin, a selective dipeptidyl peptidase-4 inhibitor, in the morphine rewarding effects in rats
- Metabotropic glutamate receptor mGlu5 is a mediator of appetite and energy balance in rats and mice
- Involvement of a mesocorticolimbic subcircuit in the reinstatement of drug context-induced cocaine-seeking in rats
- A stepped care strategy using buprenorphine and methadone versus conventional methadone maintenance in heroin dependence: a randomized controlled trial
- CART peptide in the nucleus accumbens regulates psychostimulants: Correlations between psychostimulant and CART peptide effects
- Iptakalim as a human nicotinic acetylcholine receptor antagonist
- cocaine withdrawal alters the reward omission effect and enhances traits of negative urgency in rats across multiple days of testing
- Overexpression of Shati/Nat8l, an N-acetyltransferase, in the nucleus accumbens attenuates the response to methamphetamine via activation of group II mGluRs in …
- Role of Medial Prefrontal Cortical Group II Metabotropic Glutamate Receptor in the Development of cocaine Sensitization
- Glucagon-like peptide-1 analog exendin-4 ameliorates cocaine-mediated behavior by inhibiting toll-like receptor 4 signaling in mice
- Are pharmacokinetic approaches feasible for treatment of cocaine addiction and overdose?
- Neural Mechanisms of Addiction
- Chromatin immunoprecipitation assays revealed CREB and serine 133 phospho-CREB binding to the CART gene proximal promoter
- Exendin-4 increases absence-like seizures and anxiety–depression-like behaviors in WAG/Rij rats
- The lack of conditioned place preference, but unaltered stimulatory and ataxic effects of alcohol in mGluR3-KO mice
- Subcellular & subsynaptic localization of group I metabotropic glutamate receptors in the nucleus accumbens
- Subcellular and subsynaptic localization of group I metabotropic glutamate receptors in the nucleus accumbens of cocaine-treated rats
- Effects of phentermine and fenfluramine on extracellular dopamine and serotonin in rat nucleus accumbens: therapeutic implications
- A randomised, double-blind, sham-controlled study of left prefrontal cortex 15 Hz repetitive transcranial magnetic stimulation in cocaine consumption and …
- Glucagon-like peptide 1 in the brain: where is it coming from, where is it going?
- Design, synthesis, and evaluation of N-(4-(4-phenyl piperazin-1-yl) butyl)-4-(thiophen-3-yl) benzamides as selective dopamine D3 receptor ligands
- Linker Functionalization of a Bivalent Ligand for the Study of the 5-HT2AR/5-HT2CR Heterodimer
- Enzyme-therapy approaches for the treatment of drug overdose and addiction
- Interaction of dopamine and glutamate in the context of reward
- Lorcaserin bidirectionally regulates dopaminergic function site-dependently and disrupts dopamine brain area correlations in rats
- Regulation of CART peptide expression by CREB in the rat nucleus accumbens in vivo
- Effects of baclofen and phenmetrazine on neuronal signaling pathways implicated in psychostimulant addiction
- Cholinergic modulation of circuits
- Neural Plasticity in the Ventral Tegmental Area, Aversive Motivation during Drug Withdrawal and Hallucinogenic Therapy
- Neuroscience of behavioral and pharmacological treatments for addictions
- Addiction-related behavioral problems increase during the first six months of the Covid-19 pandemic
- Recent evidence and potential mechanisms underlying weight gain and insulin resistance due to atypical antipsychotics
- Dopamine neurotransmission in the ventral tegmental area promotes active forgetting of cocaine-associated memory
- Current Pharmaceutical & Clinical Research
- Liraglutide for the Treatment of Antipsychotic Drug-Induced Weight Gain—Reply
- Effect of baclofen on morphine-induced conditioned place preference, extinction, and stress-induced reinstatement in chronically stressed mice
- Metabotropic Glutamate Receptors in Amygdala Functions
- Effects of 5-HT2C receptor modulation and the NA reuptake inhibitor atomoxetine in tests of compulsive and impulsive behaviour
- Diazepam concurrently increases the frequency and decreases the amplitude of transient dopamine release events in the nucleus accumbens
- Repetitive transcranial magnetic stimulation: Re-wiring the alcoholic human brain
- GL Gessa (Cagliari)
- cocaine-and Amphetamine-Regulated Transcript (CART) Peptide and Drug Addiction
- Central amygdala CART modulates ethanol withdrawal-induced anxiety
- Amphetamine
- Catalytic activities of a highly efficient cocaine hydrolase for hydrolysis of biologically active cocaine metabolites norcocaine and benzoylecgonine
- Stimulation of serotonin2C receptors elicits abnormal oral movements by acting on pathways other than the sensorimotor one in the rat basal ganglia
- Effects of 5-HT1A, 5-HT2A and 5-HT2C receptor agonists and antagonists on responding for a conditioned reinforcer and its enhancement by methylphenidate
- “This Isn’t the South Bronx” Race, Criminality, and Disability in the Contemporary Opioid Epidemic
- Lateral hypothalamic GLP-1 receptors are critical for the control of food reinforcement, ingestive behavior and body weight
- Orexin receptors within the nucleus accumbens shell mediate the stress but not drug priming-induced reinstatement of morphine conditioned place preference
- CART-containing neurons in the nucleus accumbens project to the ventral pallidum in the rat and may inhibit cocaine-induced locomotion
- Implications of prenatal exposure to synthetic corticosteroid in the mesolimbic reward pathway
- Soy Isoflavone extract does not increase the intoxicating effects of acute alcohol ingestion in human volunteers
- Kinetic characterization of an efficient cocaine hydrolase against toxic metabolites of cocaine
- A commentary on gender does not matter: add-on repetitive transcranial magnetic stimulation treatment for female methamphetamine dependents
- The Therapeutic Potential of
- The pleiotropic of GLP-1/GLP-1R axis in central nervous system diseases
- How fixed prices of heroin coexist with variations in consumer demand within a local heroin market LD Hoffer, SK Koester, A. Ben Abdallah and LB Cottler …
- The role of metabotropic glutamate type 5 receptors in amphetamine sensitization: Investigations in humans and rodents
- Long-term functional alterations following prenatal GLP-1R activation
- Alternative formats
- GLP-1 is both anxiogenic and antidepressant; divergent effects of acute and chronic GLP-1 on emotionality
- cocaine-and-Amphetamine Regulated Transcript (CART) peptide attenuates dopamine-and cocaine-mediated locomotor activity in both male and female rats: lack of …
- Glial cells and their contribution to the mechanisms of action of cannabidiol in neuropsychiatric disorders
- Brain Stimulation Methods for Substance Use Disorders
- Effects of escitalopram on attentional bias to cocaine-related stimuli and inhibitory control in cocaine-dependent subjects
- Unravelling the role of the cerebellum in drug addiction. Cerebellum-prefrontal networks in drug-induced preference memory
- The central serotonin2B receptor as a new pharmacological target for the treatment of dopamine-related neuropsychiatric disorders: Rationale and current status of …
- An up-to-date evaluation of lorcaserin hydrochloride for the treatment of obesity
- Localization and targeting of GIRK channels in mammalian central neurons
- STUDY#: NIDA-CPU-0003
- Effects of 5-HT, 5-HT and 5-HT receptor agonists and antagonists on responding for a conditioned reinforcer and its enhancement by methylphenidate.
- Neurochemical evidence that cocaine-and amphetamine-regulated transcript (CART) 55–102 peptide modulates the dopaminergic reward system by decreasing the …
- Recent progress in protein drug design and discovery with a focus on novel approaches to the development of anticocaine medications
- Effects of sex and prenatal stress on vulnerability to drugs
- Marijuana use among adolescents is associated with deleterious alterations in mature BDNF
- Framing the Future of Nicotine and Tobacco Research in the New Millennium: Sixth Annual Meeting Society for Research on Nicotine and Tobacco Arlington, VA, USA …
- Learning to Be a cocaine Addict: Behavioral, Pharmacological, and Molecular Characterization in Initial Learning of cocaine-Environment Associations
- Learning to be a cocaine addict: behavioral, pharmacological, and molecular characterization of individual differences in initial learning of cocaine-environment …
- Postnatal developmental profile of urocortin 1 and cocaine-and amphetamine-regulated transcript in the perioculomotor region of C57BL/6J mice
- Chairs: Thomas R. Kosten and Staci Gruber
- Long-acting glucagon-like peptide-1 receptor agonists suppress voluntary alcohol intake in male wistar rats
- A motivational and neuropeptidergic hub: anatomical and functional diversity within the nucleus accumbens shell
- Interesting rTMS Results in Healthy People
- Expression of cocaine-and amphetamine-regulated transcript in the rat forebrain during postnatal development
- Comparison of STAT3 Phosphorylation Between IDI Versus INI Isoforms and Acute Versus Chronic Treatment of the Human Serotonin 2C Receptor
- Activation of mGluR2/3 following stress hormone exposure restores sensitivity to alcohol in rats
- Nucleus accumbens cocaine-amphetamine regulated transcript mediates food intake during novelty conflict
- Scanning Sex, Stress and Substance Abuse Susceptibility: Neural Correlates of Vulnerability to Abuse Drugs.
- Effects of non-invasive brain stimulation on stimulant craving in users of cocaine, amphetamine, or methamphetamine: a systematic review and meta-analysis
- Nicotine Withdrawal and Deficits in Cognitive Flexibility: Possible Ties to Aberrations in Frontostriatal BDNF Signaling
- Functional and structural brain abnormalities in substance use disorder: A multimodal meta‐analysis of neuroimaging studies
- Utilization of Propensity Score Weighting and Targeted Maximum Likelihood Estimation in the Post Hoc Analysis of a Randomized Controlled Trial for the Treatment of …
- Central control of feeding behavior by the secretin, PACAP, and glucagon family of peptides
- Contributions to the Epidemiology of cocaine Dependence: Novel Estimates of Transition Probabilities Among Subgroups of cocaine Initiates
- Progesterone serum levels correlate negatively with craving in female postmenopausal in-patients with alcohol use disorder: A sex-and menopausal status-separated …
- Translational Neuroscience Unit Donders Institute Nijmegen
- Blockade of group II metabotropic glutamate receptors produces hyper-locomotion in cocaine pre-exposed rats by interactions with dopamine receptors
- Neuromodulating the performance monitoring network during conflict and error processing in healthy populations: Insights from transcranial electric …
- Potential antidepressant role of neurotransmitter CART: implications for mental disorders
- Sexual motivation in male rats is modulated by tropomyosin receptor kinase B (TrkB).
- Cognitive impairment: quantification and possibilities for pharmacological treatment
- Considerations for single-versus multiple-drug pharmacotherapy in the management of painful diabetic neuropathy
- The methionine aminopeptidase 2 inhibitor, TNP-470, enhances the antidiabetic properties of sitagliptin in mice by upregulating xenin
- Pregabalin abuse and addiction
- Assessment of the Possible Oxidative Hepatotoxicity Induced by Cannabis and Pregabalin in Rats
- The discovery and development of liraglutide and semaglutide
- Differential Modulation Of Oxycodone Reward And Analgesia By A Cannabinoid Derivative
- Alleviation of depression by glucagon-like peptide 1 through the regulation of neuroinflammation, neurotransmitters, neurogenesis, and synaptic function
- The potentially beneficial central nervous system activity profile of ivacaftor and its metabolites
- Leptin receptor neurons in the mouse hypothalamus are colocalized with the neuropeptide galanin and mediate anorexigenic leptin action
- Design, synthesis, and evaluation of functionalized 5-(4-arylpiperazin-1-yl)-N-arylpentanamides as selective dopamine D3 receptor ligands
- Alkaloids from the genus Duguetia
- Prevalence and risk factors of pregabalin misuse among patients with substance use disorder
- Drug-Seeking Behavior Is Significantly Attenuated in Nutritionally Supplemented cocaine Withdrawn Sprague-Dawley Rats
- Schwann cell autocrine and paracrine regulatory mechanisms, mediated by allopregnanolone and BDNF, modulate PKCε in peripheral sensory neurons
- Neural correlates of age-related memory decline and sensitivity to BDNF gene delivery
- Inhibitory role of inducible cAMP early repressor (ICER) in methamphetamine-induced locomotor sensitization
- Design, Synthesis, And Evaluation of Functionalized Diamino-butylbenzamides As Selective Dopamine D3 Receptor Ligands
- The roles of serotonin in neuropsychiatric disorders
- Effects and mechanisms of 3α, 5α,-THP on emotion, motivation, and reward functions involving pregnane xenobiotic receptor
- Synthesis of functionalized 5-(4-arylpiperazin-1-yl)-N-arylpentanamides and their evaluation as D3 receptor ligands
- Pharmacological evidence that 5-HT2C receptor blockade selectively improves decision making when rewards are paired with audiovisual cues in a rat gambling …
- Novel serotonin receptor 2 (5-HT2R) agonists and antagonists: a patent review (2004-2014)
- Misuse of pregabalin: case series and literature review
- Pregabalin versus naltrexone in alcohol dependence: a randomised, double-blind, comparison trial
- Effects of cyclotraxin-b treatment on endometriotic lesion survival in an immunocompromised mouse model
- Studies To Examine Potential Tolerability Differences between the 5-HT2C Receptor Selective Agonists Lorcaserin and CP-809101
- Acute pharmacological profile of 2C-B-Fly-NBOMe in male Wistar rats—pharmacokinetics, effects on behaviour and thermoregulation
- Sex differences in invasive and noninvasive neurotechnologies
- Effect of yohimbine stress on reacquisition of oxycodone seeking in rats
- Obesity and dietary added sugar interact to affect postprandial GLP-1 and its relationship to striatal responses to food cues and feeding behavior
- Evaluating Repetitive Transcranial Magnetic Stimulation to Reduce Opioid Cravings in Opioid Use Disorder
- GRM7 gene mutations and consequences for neurodevelopment
- Molecular and behavioral responses of zebrafish embryos/larvae after sertraline exposure
- An overview of similarities and differences in metabolic actions and effects of central nervous system between glucagon-like peptide-1 receptor agonists (GLP-1RAs) …
- Glutamate and MDMA Neurobehavioral Toxicity
- Optimizing Individual Targeting of Fronto-Amygdala Network with Transcranial Magnetic Stimulation (TMS): Biophysical, Physiological and Behavioral Variations in …
- Ligand-directed serotonin 5-HT2C receptor desensitization and sensitization
- Extremely low frequency electromagnetic field exposure and restraint stress induce changes on the brain lipid profile of Wistar rats
- Natural Striatal Signaling Dynamics During Food Approach
- Comparing Chronic Treatments of the INI and VSV Isoforms of the Human Serotonin 2C Receptor Impacting Phosphorylation of STAT3
- PRACTICE OF ISLAMIC MICROFINANCE BY DIFFERENT NON-GOVERNMENT ORGANIZATION’S IN BANGLADESH: AN EMPIRICAL EVIDENCE
- Effects of isovaline and involvement of metabotropic group ii glutamate receptors
- Development of an Animal Phenotype of Gambling Disorder: Chronic Reward Uncertainty Induces a Gambling Disorder-like State of Sensitization and …
- The neurotoxic effect of long-term use of high-dose Pregabalin and the role of alpha tocopherol in amelioration: implication of MAPK signaling with oxidative stress …
- Preclinical Development of a Novel Serotonin Receptor Modulator for Fragile X Syndrome
- Accelerated repetitive transcranial magnetic stimulation does not influence grey matter volumes in regions related to alcohol relapse: An open-label exploratory study
- The contribution of microglia to early synaptic compensatory responses that precede β-amyloid-induced neuronal death
- Identification and characterization of a novel, conserved metallo-β-lactamase regulator of dopamine and glutamate signaling
- Leptin Regulates Nutrient Reward Via Galanin and Orexin Neurons
- Dopamine depresses melanin concentrating hormone neuronal activity through multiple effects on α2-noradrenergic, D1 and D2-like dopaminergic receptors
- The Effects of Liraglutide on the Learned Control of Appetitive Behavior
- Systematic review: opioid treatment for chronic back pain: prevalence, efficacy, and association with addiction
- CHAPITRE 7. MODULATION OF GLUTAMATE RECEPTORS IN DYSKINETIC MPTP MONKEYS RECEIVING A UNILATERAL SUBTHALAMOTOMY
- Physiological and Pathophysiological Aspects of 5-HT2c Receptors in Basal Ganglia
