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August 3, 2022POLYPHENOLS AS COVID-19 TREATMENT & PREVENTION
August 3, 2022
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- Oxidative stress, toxicology, and pharmacology of CYP2E1
- Genetic polymorphism in CYP2E1: Population distribution of CYP2E1 activity
- CYP2E1 and oxidative liver injury by alcohol
- Human CYP2E1 is regulated by miR-378
- Role of CYP2E1 in the Hepatotoxicity of Acetaminophen (∗)
- CYP2E1
- CYP2E1: from ash to nash
- Human hepatic CYP2E1 expression during development
- Ethanol Induces CYP2E1 by Protein Stabilization: ROLE OF UBIQUITIN CONJUGATION IN THE RAPID DEGRADATION OF CYP2E1 (∗)
- Role of CYP2E1 in Diethylnitrosamine-Induced Hepatocarcinogenesis In vivo
- CYP2E1-dependent toxicity and oxidative stress in HepG2 cells
- Different regulation and expression of the human CYP2E1 gene due to the Rsal polymorphism in the 5′-flanking region
- Insulin signaling in the transcriptional and posttranscriptional regulation of CYP2E1 expression
- The CYP2E1-humanized transgenic mouse: role of CYP2E1 in acetaminophen hepatotoxicity
- Role of cytochromes P450 in chemical toxicity and oxidative stress: studies with CYP2E1
- Genetic polymorphism of human CYP2E1: characterization of two variant alleles
- Increased hepatocyte CYP2E1 expression in a rat nutritional model of hepatic steatosis with inflammation
- Reduction of benzene metabolism and toxicity in mice that lack CYP2E1 expression
- CYP2E1 genetic polymorphisms and risk of nasopharyngeal carcinoma in Taiwan
- CYP2E1 and risk of chemically mediated cancers
- Nrf2 is increased by CYP2E1 in rodent liver and HepG2 cells and protects against oxidative stress caused by CYP2E1
- Resistance to carbon tetrachloride-induced hepatotoxicity in mice which lack CYP2E1 expression
- CYP2E1 mediated isoniazid-induced hepatotoxicity in rats
- Chlorzoxazone is metabolized by human CYP1A2 as well as by human CYP2E1.
- CYP2E1 is not involved in early alcohol-induced liver injury
- Ethnic variation in the CYP2E1 gene: polymorphism analysis of 695 African-Americans, European-Americans and Taiwanese.
- Detection and characterization of novel polymorphisms in the CYP2E1 gene.
- Contribution of CYP2E1 and CYP3A to acetaminophen reactive metabolite formation
- CYP2E1: biochemistry, toxicology, regulation and function in ethanol-induced liver injury
- Chlorzoxazone, a selective probe for phenotyping CYP2E1 in humans.
- CYP2E1 and CYP4A as microsomal catalysts of lipid peroxides in murine nonalcoholic steatohepatitis
- Genetic and dietary predictors of CYP2E1 activity: a phenotyping study in Hawaii Japanese using chlorzoxazone
- CYP2E1—biochemical and toxicological aspects and role in alcohol-induced liver injury
- CYP2E1 activity before and after weight loss in morbidly obese subjects with nonalcoholic fatty liver disease
- Developmental Expression of CYP2E1 in the Human Liver: Hypermethylation Control of Gene Expression During the Neonatal Period
- Role of CYP2E1 in thioacetamide-induced mouse hepatotoxicity
- The alcohol-inducible form of cytochrome P450 (CYP2E1): role in toxicology and regulation of expression
- Protection against acetaminophen toxicity in CYP1A2 and CYP2E1 double-null mice
- The impact of CYP2E1 on the development of alcoholic liver disease as studied in a transgenic mouse model
- Oxidative stress mediated toxicity exerted by ethanol-inducible CYP2E1
- Hepatocyte CYP2E1 overexpression and steatohepatitis lead to impaired hepatic insulin signaling
- Induction of CYP2E1 in liver, kidney, brain and intestine during chronic ethanol administration and withdrawal: evidence that CYP2E1 possesses a rapid phase half …
- Development and properties of HepG2 cells that constitutively express CYP2E1
- Differential effects of CYP2E1 status on the metabolic activation of the colon carcinogens azoxymethane and methylazoxymethanol
- CYP2E1 genotype and isoniazid-induced hepatotoxicity in patients treated for latent tuberculosis
- Human CYP2E1 mediates the formation of glycidamide from acrylamide
- Role of CYP2E1 in the epoxidation of acrylamide to glycidamide and formation of DNA and hemoglobin adducts
- CYP2E1-mediated mechanism of anti-genotoxicity of the broccoli constituent sulforaphane
- Brain CYP2E1 is induced by nicotine and ethanol in rat and is higher in smokers and alcoholics
- Iron and CYP2E1-dependent oxidative stress and toxicity
- Genetic polymorphisms of NAT2 and CYP2E1 associated with antituberculosis drug-induced hepatotoxicity in Korean patients with pulmonary tuberculosis
- Role of CYP2E1 in ethanol-induced oxidant stress, fatty liver and hepatotoxicity
- Biotransformation of caffeine, paraxanthine, theobromine and theophylline by cDNA-expressed human CYP1A2 and CYP2E1.
- Diallylsulfide and allylmethylsulfide are uniquely effective among organosulfur compounds in inhibiting CYP2E1 protein in animal models
- CYP2E1‐mediated oxidative stress induces collagen type I expression in rat hepatic stellate cells
- In vivo and in vitro characterization of CYP2E1 activity in Japanese and Caucasians.
- CYP2E1-dependent toxicity and up-regulation of antioxidant genes
- Metabolic activation of dacarbazine by human cytochromes P450: the role of CYP1A1, CYP1A2, and CYP2E1
- Polymorphisms in GSTT1, GSTZ1, and CYP2E1, Disinfection By-products, and Risk of Bladder Cancer in Spain
- Potentiation of thioacetamide liver injury in diabetic rats is due to induced CYP2E1
- Mechanisms of down-regulation of CYP2E1 expression by inflammatory cytokines in rat hepatoma cells
- Absence of acrylamide-induced genotoxicity in CYP2E1-null mice: evidence consistent with a glycidamide-mediated effect
- Advances in the interpretation and prediction of CYP2E1 metabolism from a biochemical perspective
- Role of NQO1, MPO and CYP2E1 genetic polymorphisms in the susceptibility to childhood acute lymphoblastic leukemia
- Cytochrome P450IIE1 (CYP2E1) is induced by skatole and this induction is blocked by androstenone in isolated pig hepatocytes
- Association of CYP2E1 gene polymorphism with predisposition to cancer development
- CYP2E1 substrate inhibition: Mechanistic interpretation through an effector site for monocyclic compounds
- Transcriptional control of the rat hepatic CYP2E1 gene
- Transcriptional control of CYP2E1 in the perivenous liver region and during starvation
- Mechanism-based inactivation of human CYP2E1 by diethyldithocarbamate
- Nrf2 and antioxidant defense against CYP2E1 toxicity
- Acetaldehyde as well as ethanol is metabolized by human CYP2E1
- NAT2 and CYP2E1 polymorphisms and susceptibility to first-line anti-tuberculosis drug-induced hepatitis
- Associations of CYP1A1, GSTM1, and CYP2E1 Polymorphisms with Lung Cancer Suggest Cell Type Specificities to Tobacco Carcinogens
- Pharmacokinetic consequences of induction of CYP2E1 by ligand stabilization
- Activity of CYP2E1 and CYP3A enzymes in adults with moderate alcohol consumption: a comparison with nonalcoholics
- Loss of CYP2E1 and CYP1A2 activity as a function of acetaminophen dose: relation to toxicity
- Acetone catabolism by cytochrome P450 2E1: studies with CYP2E1-null mice
- Genetic polymorphisms of CYP2E1, GSTM1, and GSTT1; environmental factors and risk of oral cancer.
- Regulation of CYP2E1 by ethanol and palmitic acid and CYP4A11 by clofibrate in primary cultures of human hepatocytes
- Gadolinium chloride blocks alcohol-dependent liver toxicity in rats treated chronically with intragastric alcohol despite the induction of CYP2E1
- Serum deprivation-induced HepG2 cell death is potentiated by CYP2E1
- CYP2E1 enhances ethanol-induced lipid accumulation but impairs autophaghy in HepG2 E47 cells
- Effects of rifampin on CYP2E1-dependent hepatotoxicity of isoniazid in rats
- CYP2E1 activity in patients with alcoholic liver disease
- Mitochondrial CYP2E1 is sufficient to mediate oxidative stress and cytotoxicity induced by ethanol and acetaminophen
- CYP2E1-dependent oxidative stress and toxicity: role in ethanol-induced liver injury
- Lipid peroxidation, CYP2E1 and arachidonic acid metabolism in alcoholic liver disease in rats
- CYP2E1-mediated modulation of valproic acid-induced hepatocytotoxicity
- Genetic Polymorphisms of CYP2E1 and Risk of Colorectal Cancer: The Fukuoka Colorectal Cancer Study
- Genetic polymorphism of GSTM1, CYP2E1 and CYP2D6 in Egyptian bladder cancer patients
- Cytochrome P450 2E1 (CYP2E1) is essential for acrylonitrile metabolism to cyanide: comparative studies using CYP2E1-null and wild-type mice
- Inhibition of CYP3A, CYP1A and CYP2E1 activities by resveratrol and other non volatile red wine components
- Expression of CYP2E1 during human fetal development: methylation of the CYP2E1 gene in human fetal and adult liver samples
- CYP2E1 overexpression in HepG2 cells induces glutathione synthesis by transcriptional activation of γ-glutamylcysteine synthetase
- Genetic polymorphisms of NAT2, CYP2E1 and GST enzymes and the occurrence of antituberculosis drug-induced hepatitis in Brazilian TB patients
- Genotype and allele frequencies of polymorphic CYP2E1 in the Turkish population
- The FANCG Fanconi anemia protein interacts with CYP2E1: possible role in protection against oxidative DNA damage
- Ethanol induction of CYP2A5: permissive role for CYP2E1
- Allylnitrile metabolism by CYP2E1 and other CYPs leads to distinct lethal and vestibulotoxic effects in the mouse
- CYP2E1 and catalase influence ethanol sensitivity in the central nervous system
- Acetaldehyde as a substrate for ethanol-inducible cytochrome P450 (CYP2E1)
- Cytochrome P450 2E1 (CYP2E1) is the principal enzyme responsible for urethane metabolism: comparative studies using CYP2E1-null and wild-type mice
- CYP1A1, CYP2E1 and GSTM1 genetic polymorphisms. The effect of single and combined genotypes on lung cancer susceptibility in Chilean people
- Red Meat Intake, CYP2E1 Genetic Polymorphisms, and Colorectal Cancer Risk
- Molecular mechanism of trichloroethylene-induced hepatotoxicity mediated by CYP2E1
- Comparison of germ cell mutagenicity in male CYP2E1-null and wild-type mice treated with acrylamide: evidence supporting a glycidamide-mediated effect
- Low doses of nicotine and ethanol induce CYP2E1 and chlorzoxazone metabolism in rat liver
- Role of CYP3A and CYP2E1 in alcohol-mediated increases in acetaminophen hepatotoxicity: comparison of wild-type and CYP2E1 (–/–) mice
- Insulin effects on CYP2E1, 2B, 3A, and 4A expression in primary cultured rat hepatocytes
- Overexpression of CYP2E1 in mitochondria sensitizes HepG2 cells to the toxicity caused by depletion of glutathione
- Induction of catalase, alpha, and microsomal glutathione S‐transferase in CYP2E1 overexpressing HepG2 cells and protection against short‐term oxidative stress
- Tissue-specific expression and methylation of the human CYP2E1 gene
- Evaluation of caffeine as a test drug for CYP1A2, NAT2 and CYP2E1 phenotyping in man by in vivo versus in vitro correlations.
- Induction and recovery time course of rat brain CYP2E1 after nicotine treatment
- Histone modification-mediated CYP2E1 gene expression and apoptosis of HepG2 cells
- Genetic variations of NAT2 and CYP2E1 and isoniazid hepatotoxicity in a diverse population
- Association between CYP2E1 genetic polymorphisms and lung cancer risk: a meta-analysis
- Expression, catalytic activity, and inducibility of cytochrome P450 2E1 (CYP2E1) in the rat central nervous system
- Genetic polymorphisms in GSTM1,-P1,-T1, and CYP2E1 and the risk of adult brain tumors
- The human CYP2E1 gene and lung cancer: DraI and RsaI restriction fragment length polymorphisms in a Finish study population
- Taurine protects acetaminophen-induced oxidative damage in mice kidney through APAP urinary excretion and CYP2E1 inactivation
- Synergistic toxicity of iron and arachidonic acid in HepG2 cells overexpressing CYP2E1
- Post-transcriptional regulation of rat CYP2E1 expression: role of CYP2E1 mRNA untranslated regions in control of translational efficiency and message stability
- CYP2E1* 1D regulatory polymorphism: association with alcohol and nicotine dependence
- Ethanol‐mediated carcinogenesis in the human esophagus implicates CYP2E1 induction and the generation of carcinogenic DNA‐lesions
- Role of alcohol and genetic polymorphisms of CYP2E1 and ALDH2 in breast cancer development
- Identification of novel toxicity-associated metabolites by metabolomics and mass isotopomer analysis of acetaminophen metabolism in wild-type and CYP2E1 …
- Bimodal targeting of microsomal CYP2E1 to mitochondria through activation of an N-terminal chimeric signal by cAMP-mediated phosphorylation
- Allele and genotype frequencies of polymorphic cytochromes P450 (CYP2C9, CYP2C19, CYP2E1) and dihydropyrimidine dehydrogenase (DPYD) in the Egyptian …
- Role of CYP2D6, CYP1A1, CYP2E1, GSTT1, and GSTM1 genes in the susceptibility to acute leukemias
- Inhibition of chlorzoxazone metabolism, a clinical probe for CYP2E1, by a single ingestion of watercress
- Lipopolysaccharide-induced liver injury in rats treated with the CYP2E1 inducer pyrazole
- Elucidation of CYP2E1 5′ regulatory RsaI/Pstl allelic variants and their role in risk for oral cancer
- The role of CYP2E1 and 2B1 in metabolic activation of benzene derivatives
- The investigation into CYP2E1 in relation to the level of response to alcohol through a combination of linkage and association analysis
- Analysis of differential substrate selectivities of CYP2B6 and CYP2E1 by site-directed mutagenesis and molecular modeling
- Construction and assessment of models of CYP2E1: predictions of metabolism from docking, molecular dynamics, and density functional theoretical calculations
- Acetoacetate induces CYP2E1 protein and suppresses CYP2E1 mRNA in primary cultured rat hepatocytes
- The RsaI polymorphism of CYP2E1 and susceptibility to alcoholic liver disease in Caucasians: effect on age of presentation and dependence on alcohol …
- Effect of ethanol on cytochrome P450 2E1 (CYP2E1), lipid peroxidation, and serum protein adduct formation in relation to liver pathology pathogenesis
- Metabolism of benzene in human liver microsomes: individual variations in relation to CYP2E1 expression
- Phyllanthus urinaria extract attenuates acetaminophen induced hepatotoxicity: involvement of cytochrome P450 CYP2E1
- Constitutive and inducible expression of hepatic CYP2E1 in leptin-deficient ob/ob mice
- CYP2E1 and NQO1 genotypes, smoking and bladder cancer
- Study of polymorphisms in the CYP2E1 gene in patients with alcoholic pancreatitis
- The GST T1 and CYP2E1 genotypes are possible factors causing vinyl chloride induced abnormal liver function
- Role of the Liver-Enriched Transcription Factor HNF-1α in Expression of the CYP2E1 Gene
- Ontogeny of hepatic CYP1A2 and CYP2E1 expression in rat
- Metabolism of dapsone to its hydroxylamine by CYP2E1 in vitro and in vivo
- Expression of CYP2E1 increases oxidative stress and induces apoptosis of cardiomyocytes in transgenic mice
- Cytochrome P450 CYP2E1, but not nicotinamide adenine dinucleotide phosphate oxidase, is required for ethanol‐induced oxidative DNA damage in rodent liver
- The effect of ethanol-induced CYP2E1 on proteasome activity: the role of 4-hydroxynonenal
- Regional and cellular distribution of CYP2E1 in monkey brain and its induction by chronic nicotine
- Association of genetic polymorphisms in CYP2E1, MPO, NQO1, GSTM1, and GSTT1 genes with benzene poisoning.
- Variation in induction of human placental CYP2E1: possible role in susceptibility to fetal alcohol syndrome?
- Genetic polymorphisms of CYP1A1, CYP2E1, GSTM1, and GSTT1 associated with head and neck cancer
- Rapid changes in cytochrome P4502E1 (CYP2E1) activity and other P450 isozymes following ethanol withdrawal in rats
- Risk assessment: toxicity from chemical exposure resulting from enhanced expression of CYP2E1
- … for the Expression of Recombinant Human Cytochrome P450s inEscherichia coliUsing Bacterial Signal Peptides: Expression of CYP3A4, CYP2A6, and CYP2E1
- Relationship between mRNA levels quantified by reverse transcription-competitive PCR and metabolic activity of CYP3A4 and CYP2E1 in human liver
- Genetic polymorphism analysis of cytochrome P4502E1 (CYP2E1) in Chinese Han populations from four different geographic areas of Mainland China
- Transgenic alfalfa plants co-expressing glutathione S-transferase (GST) and human CYP2E1 show enhanced resistance to mixed contaminates of heavy metals and …
- Characterization of cytochrome P4502E1 turnover in transfected HepG2 cells expressing human CYP2E1
- Polymorphism in cytochrome P450 CYP2D6, CYP1A1, CYP2E1 and glutathione S-transferase, GSTM1, GSTM3, GSTT1 and susceptibility to tobacco-related cancers …
- Construction of a CYP2E1-template system for prediction of the metabolism on both site and preference order
- Trade herbal products and induction of CYP2C19 and CYP2E1 in cultured human hepatocytes
- Removal of glutathione produces apoptosis and necrosis in HepG2 cells overexpressing CYP2E1
- CYP2E1 is preferentially expressed in Clara cells of murine lung: localization by in situ hybridization and immunohistochemical methods.
- NQO1, MPO, CYP2E1, GSTT1 and GSTM1 polymorphisms and biological effects of benzene exposure—a literature review
- Spectrophotometric Analysis of Human CYP2E1-Catalyzed p-Nitrophenol Hydroxylation
- An interaction between the cytochrome P450 probe substrates chlorzoxazone (CYP2E1) and midazolam (CYP3A)
- Heteromeric complex formation between CYP2E1 and CYP1A2: evidence for the involvement of electrostatic interactions
- CYP2E1 induced by ethanol causes oxidative stress, proteasome inhibition and cytokeratin aggresome (Mallory body-like) formation
- Pharmacokinetics of theophylline in diabetes mellitus rats: induction of CYP1A2 and CYP2E1 on 1, 3-dimethyluric acid formation
- Inhibition of CYP2E1 Reverses CD4+ T-Cell Alterations in Trichloroethylene-Treated MRL+/+ Mice
- Genetic polymorphisms of CYP2D6, CYP1A1 and CYP2E1 in the South-Amerindian population of Chile.
- Amelioration of oxidative stress by dandelion extract through CYP2E1 suppression against acute liver injury induced by carbon tetrachloride in sprague‐dawley rats
- CYP2E1-dependent hepatotoxicity and oxidative damage after ethanol administration in human primary hepatocytes
- St. John’s wort extract induces CYP3A and CYP2E1 in the Swiss Webster mouse
- Effect of antifungal drugs on cytochrome P450 (CYP) 1A2, CYP2D6, and CYP2E1 activities in human liver microsomes
- Inhibition of CYP2E1 catalytic activity in vitro by S-adenosyl-L-methionine
- Combined analysis of germline polymorphisms of p53, GSTM1, GSTT1, CYP1A1, and CYP2E1: relation to the incidence rate of cervical carcinoma
- Immunohistochemical demonstration of the expression of CYP2E1 in human breast tumour and non-tumour tissues
- Major tanshinones of Danshen (Salvia miltiorrhiza) exhibit different modes of inhibition on human CYP1A2, CYP2C9, CYP2E1 and CYP3A4 activities in vitro
- Genetic polymorphisms in cytochrome P450 (CYP) 1A1, CYP1A2, CYP2E1, glutathione S-transferase (GST) M1 and GSTT1 and susceptibility to prostate cancer in the …
- Modeling interchild differences in pharmacokinetics on the basis of subject-specific data on physiology and hepatic CYP2E1 levels: a case study with toluene
- A significantly joint effect between arsenic and occupational exposures and risk genotypes/diplotypes of CYP2E1, GSTO1 and GSTO2 on risk of urothelial carcinoma
- CYP2E1 regulation by benzene and other small organic chemicals in rat liver and peripheral lymphocytes
- Metabolic oxidation and toxification of N-methylformamide catalyzed by the cytochrome P450 isoenzyme CYP2E1.
- Differential Modulation of CYP2E1 Activity by CAMP-Dependent Protein Kinase upon Ser129Replacement
- Kinetic characterization of CYP2E1 inhibition in vivo and in vitro by the chloroethylenes
- Translational activation of ethanol-inducible cytochrome P450 (CYP2E1) by isoniazid
- Effects of occupation, lifestyle and genetic polymorphisms of CYP1A1, CYP2E1, GSTM1 and GSTT1 on urinary 1-hydroxypyrene and 2-naphthol concentrations
- Distribution and differential induction of CYP2E1 by ethanol and acetone in the mesocorticolimbic system of rat
- Identification and characterization of a mitochondrial targeting signal in rat cytochrome P450 2E1 (CYP2E1)
- Investigation of xenobiotics metabolism, genotoxicity, and carcinogenicity using CYP2E1-/-mice
- CYP2E1 overexpression alters hepatocyte death from menadione and fatty acids by activation of ERK1/2 signaling
- Analysis of CYP2E1 polymorphism for the determination of genetic susceptibility to gastric cancer in Koreans
- Obesity-induced increase of CYP2E1 activity and its effect on disposition kinetics of chlorzoxazone in Zucker rats
- Lung cancer risk in relation to the CYP2E1 Rsa I genetic polymorphism among African-Americans and Caucasians in Los Angeles County.
- Polymorphism in CYP1A1 and CYP2E1 genes and susceptibility to leukoplakia in Indian tobacco users
- Early Alcoholic Liver Injury: Formation of Protein Adducts with Acetaldehyde and Lipid Peroxidation Products, and Expression of CYP2E1 AND CYP3A
- Frequencies of genotypes and alleles of the functional SNPs in CYP2C19 and CYP2E1 in mainland Chinese Kazakh, Uygur and Han populations
- CYP1A1 CYP2E1 and GSTM1 polymorphisms are not associated with susceptibility to squamous‐cell carcinoma of the esophagus
- Influence of CYP1A1, CYP2E1, GSTM3 and NAT2 genetic polymorphisms in oral cancer susceptibility: results from a case-control study in Rio de Janeiro
- Effects of cytochrome P450 (CYP) 2A6 gene deletion and CYP2E1 genotypes on gastric adenocarcinoma
- Involvement of CYP2E1 as a low-affinity enzyme in phenacetin O-deethylation in human liver microsomes
- Adenovirus-mediated expression of CYP2E1 produces liver toxicity in mice
- Metabolic activation of N-alkylnitrosamines in genetically engineered Salmonella typhimurium expressing CYP2E1 or CYP2A6 together with human NADPH …
- Combined metadoxine and garlic oil treatment efficaciously abrogates alcoholic steatosis and CYP2E1 induction in rat liver with restoration of AMPK activity
- A Novel Polymorphism rs1329149 of CYP2E1 and a Known Polymorphism rs671 of ALDH2 of Alcohol Metabolizing Enzymes Are Associated with Colorectal Cancer …
- Association of CYP2E1 and NAT2 gene polymorphisms with chronic obstructive pulmonary disease
- CYP2A6 and CYP2E1 polymorphisms in a Brazilian population living in Rio de Janeiro
- Microsomal ethanol oxidizing system: transcriptional and posttranscriptional regulation of cytochrome P450, CYP2E1.
- Mitochondrial dysfunction by γ-irradiation accompanies the induction of cytochrome P450 2E1 (CYP2E1) in rat liver
- Role of CYP2E1 genotypes in susceptibility to colorectal cancer in the Kashmiri population
- Acetaldehyde generating enzyme systems: roles of alcohol dehydrogenase, CYP2E1 and catalase, and speculations on the role of other enzymes and processes
- Inactivation of stress protein p8 increases murine carbon tetrachloride hepatotoxicity via preserved CYP2E1 activity
- Lycopene attenuates alcoholic apoptosis in HepG2 cells expressing CYP2E1
- CYP2E1 degradation by in vitro reconstituted systems: role of the molecular chaperone hsp90
- CYP1A1, CYP2D6, CYP2E1, NAT2, GSTM1 and GSTT1 polymorphisms or their combinations are associated with the increased risk of the laryngeal squamous cell …
- Induction of nicotine-metabolizing CYP2B1 by ethanol and ethanol-metabolizing CYP2E1 by nicotine: summary and implications
- Expression of CYP2E1 in human nasopharynx and its metabolic effect in vitro
- Role of p38 MAPK in CYP2E1-dependent arachidonic acid toxicity
- Genetic Polymorphisms of ADH1C and CYP2E1 and Risk of Oral Squamous Cell Carcinoma
- Ethnic susceptibility to lung cancer: differences in CYP2E1, CYP1A1 and GSTM1 genetic polymorphisms between French Caucasian and Chilean populations
- CYP2E1 expression in human lymphocytes from various ethnic populations
- Association between CYP2E1 polymorphisms and susceptibility to prostate cancer
- CYP2E1 potentiation of LPS and TNFα-induced hepatotoxicity by mechanisms involving enhanced oxidative and nitrosative stress, activation of MAP kinases …
- CYP2E1-dependent benzene toxicity: the role of extrahepatic benzene metabolism
- The effects of alcohol and diallyl sulphide on CYP2E1 activity in humans: a phenotyping study using chlorzoxazone
- Distribution of ADH1B, ALDH2, CYP2E1∗ 6, and CYP2E1∗ 7B genotypes in Turkish population
- The effect of CYP2E1-dependent oxidant stress on activity of proteasomes in HepG2 cells
- Genetic polymorphism of CYP2E1, ADH2, and ALDH2 in Mexican-Americans
- Effect of ALDH2 and CYP2E1 Gene Polymorphisms on Drinking Behavior and Alcoholic Liver Disease in Japanese Male Workers
- Tandem Repeat Polymorphism of the CYP2E1 Gene: An Association Study With Esophageal Cancer and Lung Cancer
- The pig CYP2E1 promoter is activated by COUP-TF1 and HNF-1 and is inhibited by androstenone
- CYP1A2* 1C, CYP2E1* 5B, and GSTM1 polymorphisms are predictors of risk and poor outcome in head and neck squamous cell carcinoma patients
- Polymorphisms in glutathione S‐transferases GSTM1, GSTT1 and GSTP1 and cytochromes P450 CYP2E1 and CYP1A1 and susceptibility to cirrhosis or …
- DNA damage and cytotoxicity in pancreatic β-cells expressing human CYP2E1
- Cytochrome P4502E1 (CYP2E1) expression in peripheral blood lymphocytes: evaluation in hepatitis C and diabetes
- Molecular modelling of human CYP2E1 by homology with the CYP102 haemoprotein domain: investigation of the interactions of substrates and inhibitors within the …
- Relationship in healthy subjects between CYP2E1 genetic polymorphisms and the 6-hydroxyIation of chlorzoxazone: a putative measure of CYP2E1 activity
- Pharmacokinetics of chlorzoxazone in rats with diabetes: induction of CYP2E1 on 6-hydroxychlorzoxazone formation
- Significance of genetic polymorphisms at multiple loci of CYP2E1 in the risk of development of childhood acute lymphoblastic leukemia
- The effect of isoniazid on CYP2E1-and CYP4A-mediated hydroxylation of arachidonic acid in the rat liver and kidney
- Immunohistochemical study of CYP2E1 in hepatocellular carcinoma carcinogenesis: examination with newly prepared anti-human CYP2E1 antibody
- Human hepatocytes are protected from ethanol-induced cytotoxicity by DADS via CYP2E1 inhibition
- Genetic polymorphism of the CYP1A1, CYP2E1, GSTM1 and GSTT1 genes and lung cancer susceptibility in a north Indian population
- Cytochrome CYP2E1 phenotyping and genotyping in the evaluation of health risks from exposure to polluted environments
- Growth retardation of fetal rats exposed to nicotine in utero: Possible involvement of CYP1A1, CYP2E1, and P‐glycoprotein
- Association of GSTM1, CYP1A1 and CYP2E1 genetic polymorphisms with susceptibility to lung adenocarcinoma: A case‐control study in Chinese population
- Induction of hepatic CYP2E1 by a subtoxic dose of acetaminophen in rats: increase in dichloromethane metabolism and carboxyhemoglobin elevation
- CYP2E1 Rsa I polymorphism impacts on risk of colorectal cancer association with smoking and alcohol drinking
- The impact of CYP2E1 genetic variability on risk assessment of VOC mixtures
- Protective effects of goldenseal (Hydrastis canadensis L.) on acetaminophen-induced hepatotoxicity through inhibition of CYP2E1 in rats
- Rat hepatic CYP2E1 is induced by very low nicotine doses: an investigation of induction, time course, dose response, and mechanism
- CYP2A6/2A7 and CYP2E1 expression in human oesophageal mucosa: regional and inter-individual variation in expression and relevance to nitrosamine metabolism
- Global Analysis of Protein− Protein Interactions Reveals Multiple CYP2E1− Reductase Complexes
- Differential role of CYP2E1 binders and isoniazid on CYP2E1 protein modification in NADPH-dependent microsomal oxidative reactions: free radical scavenging …
- Antioxidant and pro-oxidant effects of a manganese porphyrin complex against CYP2E1-dependent toxicity
- Polymorphisms of CYP1a1, CYP2E1, GSTM1, GSTT1, and TP53 genes in Amerindians
- CYP1A1, CYP2E1, GSTM1, GSTT1, EPHX1 exons 3 and 4, and NAT2 polymorphisms, smoking, consumption of alcohol and fruit and vegetables and risk of head and …
- CYP2E1 Rsa I/Pst I polymorphism is associated with lung cancer risk among Asians
- The role of CYP2A and CYP2E1 in the metabolism of 3-methylindole in primary cultured porcine hepatocytes
- Homology modelling of human CYP2E1 based on the CYP2C5 crystal structure: investigation of enzyme–substrate and enzyme–inhibitor interactions
- Studies on interindividual variations of CYP2E1 using chlorzoxazone as an in vivo probe
- A Case–control and a family-based association study revealing an association between CYP2E1 polymorphisms and nasopharyngeal carcinoma risk …
- Functional polymorphism in porcine CYP2E1 gene: Its association with skatole levels
- Identification of CYP2E1 in marmoset monkey
- Effects of diabetes on rabbit kidney and lung CYP2E1 and CYP2B4 expression and drug metabolism and potentiation of carcinogenic activity of N …
- Does CYP2E1 play a major role in the aggravation of isoniazid toxicity by rifampicin in human hepatocytes?
- Relationship between genetic polymorphisms of metabolizing enzymes CYP2E1, GSTM1 and Kazakh’s esophageal squamous cell cancer in Xinjiang, China
- ADH2 and CYP2E1 genetic polymorphisms: risk factors for alcohol-related birth defects
- Renal and hepatic accumulation of cadmium and lead in the expression of CYP4F2 and CYP2E1
- Ageing is associated with increased expression but decreased activity of CYP2E1 in male Wistar rats
- Metallothionein 2A induction by zinc protects HEPG2 cells against CYP2E1-dependent toxicity
- Porcine CYP2A19, CYP2E1 and CYP1A2 forms are responsible for skatole biotransformation in the reconstituted system
- Effect of cigarette smoke on hepatic and pulmonary cytochromes P450 in mouse: evidence for CYP2E1 induction in lung
- CYP2E1 and ALDH2 genotypes and alcohol dependence in Japanese
- Effect of fasting and obesity in humans on the 6‐hydroxylation of chlorzoxazone: a putative probe of CYP2E1 activity
- Benzene-induced genotoxicity in mice in vivo detected by the alkaline comet assay: reduction by CYP2E1 inhibition
- Adverse Birth Outcomes Associated with Maternal Smoking and Polymorphisms in the N-Nitrosamine-Metabolizing Enzyme Genes NQO1 and CYP2E1
- NADPH-dependent microsomal electron transfer increases degradation of CYP2E1 by the proteasome complex: role of reactive oxygen species
- Hypomethylation and hypoexpression of human CYP2E1 gene in lung tumors
- GSTT1 and CYP2E1 polymorphisms and trihalomethanes in drinking water: effect on childhood leukemia.
- Inhibition of CYP2E1 with natural agents may be a feasible strategy for minimizing the hepatotoxicity of ethanol
- A High Throughput Screening Assay to Screen for CYP2E1 Metabolism and Inhibition Using a Fluorogenic Vivid® P450 Substrate
- Ethanol and arachidonic acid produce toxicity in hepatocytes from pyrazole-treated rats with high levels of CYP2E1
- GSTT1, GSTM1 and CYP2E1 genetic polymorphisms in gastric cancer and chronic gastritis in a Brazilian population
- A temporal study on the histopathological, biochemical and molecular responses of CCl4-induced hepatotoxicity in CYP2E1-null mice
- Effects of Ganoderma lucidum polysaccharide on CYP2E1, CYP1A2 and CYP3A activities in BCG-immune hepatic injury in rats
- Expression of CYP2E1 in Human Lung and Kidney during Development and in Full‐Term Placenta: A Differential Methylation of the Gene is Involved in the …
- Comparative metabolism and disposition of trichloroethylene in CYP2E1–/–and wild-type mice
- Inhibition of cytochrome P450 enzymes participating in p-nitrophenol hydroxylation by drugs known as CYP2E1 inhibitors
- Chlorzoxazone as a single sample probe of hepatic CYP2E1 activity in humans
- Kupffer cell inactivation alleviates ethanol-induced steatosis and CYP2E1 induction but not inflammatory responses in rat liver
- Protective effects of emodin and chrysophanol isolated from marine fungus Aspergillus sp. on ethanol-induced toxicity in HepG2/CYP2E1 cells
- Association of combined CYP2E1 gene polymorphism with the risk for esophageal squamous cell carcinoma in Huai’an population, China
- Covalent immobilization of recombinant human cytochrome CYP2E1 and glucose-6-phosphate dehydrogenase in alumina membrane for drug screening applications
- Promoter function and the role of cytokines in the transcriptional regulation of rabbit CYP2E1 and CYP2E2
- Differential effects of diabetes on CYP2E1 and CYP2B4 proteins and associated drug metabolizing enzyme activities in rabbit liver
- … exposure to styrene: modulation of cytogenetic damage and levels of urinary metabolites of styrene by polymorphisms in genes CYP2E1, EPHX1, GSTM1, GSTT1 …
- Relationship between alcoholism and CYP2E1 C/D polymorphism
- Polymorphism of metabolizing genes and lung cancer histology: prevalence of CYP2E1 in adenocarcinoma
- Differential effects of dietary fatty acids on the regulation of CYP2E1 and protein kinase C in human hepatoma HepG2 cells
- Cytochrome P4502E1 (CYP2E1) genetic polymorphism in a case-control study of gastric cancer and liver disease.
- Lymphocyte cytochrome P450-CYP2E1 expression in human IDDM subjects
- Role of calcium and calcium-activated proteases in CYP2E1-dependent toxicity in HEPG2 cells
- Oxidative stress potentiated by diallylsulfide, a selective CYP2E1 inhibitor, in isoniazid toxic effect on rat primary hepatocytes
- Relationship between genetic polymorphisms of drug-metabolizing enzymes (CYP1A1, CYP2E1, GSTM1, and NAT2), drinking habits, histological subtypes, and p53 …
- The mode of cisplatin-induced cell death in CYP2E1-overexpressing HepG2 cells: modulation by ERK, ROS, glutathione, and thioredoxin
- Role of intracellular calcium and phospholipase A2 in arachidonic acid-induced toxicity in liver cells overexpressing CYP2E1
- Helicobacter pylori infection, but not genetic polymorphism of CYP2E1, is highly prevalent in gastric cancer patients younger than 40 years
- Role of CYP2E1 immunoglobulin G4 subclass antibodies and complement in pathogenesis of idiosyncratic drug-induced hepatitis
- A negative cooperativity mechanism of human CYP2E1 inferred from molecular dynamics simulations and free energy calculations
- Hormone controlled phosphorylation and degradation of CYP2B1 and CYP2E1 in isolated rat hepatocytes
- Effects of the ADH3, CYP2E1, and GSTP1 genetic polymorphisms on their expressions in Caucasian lung tissue
- Genetic polymorphism of the CYP2E1 gene and susceptibility to Parkinson’s disease in Taiwanese
- Transcription factor Nrf2 protects HepG2 cells against CYP2E1 plus arachidonic acid-dependent toxicity
- Differential in vivo effects of α‐naphthoflavone and β‐naphthoflavone on CYP1A1 and CYP2E1 in rat liver, lung, heart, and kidney
- cDNA sequence, deduced amino acid sequence, predicted gene structure and chemical regulation of mouse CYP2E1
- … and CYP2E1 and N‐terminal truncated CYP1A1 proteins in Saccharomyces cerevisiae − role of protein kinase A in the mitochondrial targeting of CYP2E1
- CYP2E1 PstI/RsaI polymorphism and colorectal cancer risk: a meta-analysis
- Lipopolysaccharide induces CYP2E1 in astrocytes through MAP kinase kinase-3 and C/EBPβ and-δ
- Inhibition of urethane-induced genotoxicity and cell proliferation in CYP2E1-null mice
- Depletion of cytosolic or mitochondrial thioredoxin increases CYP2E1-induced oxidative stress via an ASK-1–JNK1 pathway in HepG2 cells
- Theoretical study of the mechanism of acetaldehyde hydroxylation by compound I of CYP2E1
- Molecular modelling of CYP2E1 enzymes from rat, mouse and man: an explanation for species differences in butadiene metabolism and potential carcinogenicity, and …
- The molecular mechanism regulating 24‐hour rhythm of CYP2E1 expression in the mouse liver
- Ethanol‐related cytotoxicity catalyzed by CYP2E1‐dependent generation of reactive oxygen intermediates in transduced HepG2 cells
- Validation of the (ω-l)-hydroxylation of lauric acid as an in vitro substrate probe for human liver CYP2E1
- The ADH3* 2 and CYP2E1 c2 alleles increase the risk of alcoholism in Mexican American men
- Interindividual variability of chlorzoxazone 6‐hydroxylation in men and women and its relationship to CYP2E1 genetic polymorphisms
- Impact of CYP2E1 genotype in renal cell and urothelial cancer patients
- Docosahexaenoic acid induces apoptosis in CYP2E1-containing HepG2 cells by activating the c-Jun N-terminal protein kinase related mitochondrial damage
- Decreased protein and mRNA expression of ER stress proteins GRP78 and GRP94 in HepG2 cells over-expressing CYP2E1
- Role of CYP2E1 activity in endoplasmic reticulum ubiquitination, proteasome association, and the unfolded protein response
- Sodium salicylate increases CYP2E1 levels and enhances arachidonic acid toxicity in HepG2 cells and cultured rat hepatocytes
- Distribution of cytochrome CYP2E1 in murine liver after ethanol and acetone administration
- Contribution of CYP2E1 to N-methyl-2-pyrrolidone metabolism
- Induction and regulation of CYP2E1 in murine liver after acute and chronic acetone administration.
- Phenobarbital induces monkey brain CYP2E1 protein but not hepatic CYP2E1, in vitro or in vivo chlorzoxazone metabolism
- Ethanol-induced oxidative DNA damage and CYP2E1 expression in liver tissue of Aldh2 knockout mice
- Modification of CYP2E1 and CYP3A4 activities in haemoglobin E-beta thalassemia patients
- Changes of CYP2E1 activity in diabetic rat model
- Use of molecular simulation for mapping conformational CYP2E1 epitopes
- Ethanol enhanced the genotoxicity of acrylamide in human, metabolically competent HepG2 cells by CYP2E1 induction and glutathione depletion
- Global patterns of variation in allele and haplotype frequencies and linkage disequilibrium across the CYP2E1 gene
- The cytochrome P-450 isoenzyme CYP2E1 in the biological processing of industrial chemicals: consequences for occupational and environmental medicine
- Differential metabolism of acrylonitrile to cyanide is responsible for the greater sensitivity of male vs female mice: role of CYP2E1 and epoxide hydrolases
- CYP2E1 expression in bone marrow and its intra-and interspecies variability: approaches for a more reliable extrapolation from one species to another in the risk …
- Role of CYP2E1 and saturation kinetics in the bioactivation of thioacetamide: Effects of diet restriction and phenobarbital
- Stable expression of human CYP2E1 in Chinese hamster cells: high sensitivity to N, N-dimethylnitrosamine in cytotoxicity testing
- Immunological detection of CYP2E1 in fresh rat lymphocytes and its pretranslational induction by fasting
- The induction of the human hepatic CYP2E1 gene by interleukin 4 is transcriptional and regulated by protein kinase C
- Comparison of genetic polymorphisms of CYP2E1, ADH2, and ALDH2 genes involved in alcohol metabolism in Koreans and four other ethnic groups
- Identification of inhibitory component in cinnamon—o-methoxycinnamaldehyde inhibits cyp1a2 and CYP2E1—
- Hepatic and pulmonary microsomal benzene metabolism in CYP2E1 knockout mice
- … in urea in conjunction with L-arginine metabolism in the liver leads to induction of cytochrome P450 2E1 (CYP2E1): The role of urea in CYP2E1 induction by acute …
- Effect of chronic disulfiram administration on the activities of CYP1A2, CYP2C19, CYP2D6, CYP2E1, and N‐acetyltransferase in healthy human subjects
- Detection of auto-antibodies against cytochrome P4502E1 (CYP2E1) in chronic hepatitis C
- CYP2E1-catalyzed oxidation contributes to the sperm toxicity of 1-bromopropane in mice
- Protective effects of loquat (Eriobotrya japonica) leaves against ethanol-induced toxicity in HepG2 cells transfected with CYP2E1
- Transfected HepG2 cells for evaluation of catechin effects on alcohol-induced CYP2E1 cytotoxicity
- Safrole-DNA adducts in human peripheral blood—an association with areca quid chewing and CYP2E1 polymorphisms
- Increased bioaccumulation of urethane in CYP2E1-/-versus CYP2E1+/+ mice
- Spin trapping agents (Tempol and POBN) protect HepG2 cells overexpressing CYP2E1 against arachidonic acid toxicity
- Age-related changes in the protein and mRNA levels of CYP2E1 and CYP3A isoforms as well as in their hepatic activities in Wistar rats. What role for oxidative stress?
- Functional CYP2E1 is required for substantial in vivo formation of 2, 5-hexanedione from n-hexane in the mouse
- Metabolism of ethyl carbamate by pulmonary cytochrome P450 and carboxylesterase isozymes: involvement of CYP2E1 and hydrolase A
- Genetic Repeat Polymorphism in the Regulating Region of CYP2E1: Frequency and Relationship With Enzymatic Activity in Alcoholics
- … by allyl sulfides and phenethyl isothiocyanate of methyl-n-pentylnitrosamine depentylation by rat esophageal microsomes, human and rat CYP2E1, and Rat CYP2A3
- Effects of ALDH2, CYP1A1, and CYP2E1 genetic polymorphisms and smoking and drinking habits on toluene metabolism in humans
- Therapeutic hypothermia-induced pharmacokinetic alterations on CYP2E1 chlorzoxazone-mediated metabolism in a cardiac arrest rat model
- Investigation of bioactivation and toxicity of styrene in CYP2E1 transgenic cells
- Increased prooxidant production and enhanced susceptibility to glutathione depletion in HepG2 cells co‐expressing HCV core protein and CYP2E1
- Acute ethanol pretreatment increases FAS-mediated liver injury in mice: role of oxidative stress and CYP2E1-dependent and-independent pathways
- DNA repair XRCC1 Arg399Gln polymorphism alone, and in combination with CYP2E1 polymorphisms significantly contribute to the risk of development of childhood …
- Do Endogenous Volatile Organic Chemicals Measured in Breath Reflect and Maintain CYP2E1 Levelsin Vivo?
- XRCC1 and CYP2E1 Polymorphisms as Susceptibility Factors of Plasma Mutant p53 Protein and Anti-p53 Antibody Expression in Vinyl Chloride …
- Evidence of association of the CYP2E1 genetic polymorphism with micronuclei frequency in human peripheral blood
- Human variability for metabolic pathways with limited data (CYP2A6, CYP2C9, CYP2E1, ADH, esterases, glycine and sulphate conjugation)
- CYP2E1 mRNA expression, genetic polymorphisms in peripheral blood lymphocytes and liver abnormalities in Chinese VCM-exposed workers
- Role of CYP1A2 and CYP2E1 in the pentoxifylline ciprofloxacin drug interaction
- Comparison of the susceptibility of wild-type and CYP2E1 knockout mice to the hepatotoxic and pneumotoxic effects of styrene and styrene oxide
- High inducibility of mouse renal CYP2E1 gene by tobacco smoke and its possible effect on DNA single strand breaks
- Effect of the CYP2E1 genotype on vinyl chloride monomer-induced liver fibrosis among polyvinyl chloride workers
- Gene–environmental interactions between alcohol-drinking behavior and ALDH2 and CYP2E1 polymorphisms and their impact on micronuclei frequency in human …
- Duration of cytochrome P-450 2E1 (CYP2E1) inhibition and estimation of functional CYP2E1 enzyme half-life after single-dose disulfiram administration in humans
- Induction of CYP2E1 activity in liver transplant patients as measured by chlorzoxazone 6‐hydroxylation
- Diallyl sulfide inhibition of CYP2E1 does not rescue diabetic rats from thioacetamide-induced mortality
- Pulmonary bioactivation of trichloroethylene to chloral hydrate: relative contributions of CYP2E1, CYP2F, and CYP2B1
- The 2006 bernard B. Brodie award lecture: CYP2E1
- Differential induction of ethanol-metabolizing CYP2E1 and nicotine-metabolizing CYP2B1/2 in rat liver by chronic nicotine treatment and voluntary ethanol intake
- Effects of genetic polymorphisms of CYP1A1, CYP2E1, GSTM1, and GSTT1 on the urinary levels of 1-hydroxypyrene and 2-naphthol in aircraft maintenance workers
- Genetic polymorphisms of CYP2E1 and GSTM1 in a Thai population
- DLPC attenuates alcohol-induced cytotoxicity in HepG2 cells expressing CYP2E1
- Role of polymorphic CYP2E1 and CYP2D6 genes in NNK-induced chromosome aberrations in cultured human lymphocytes
- A comparison of substrate dynamics in human CYP2E1 and CYP2A6
- S-adenosyl-L-methionine attenuates hepatotoxicity induced by agonistic Jo2 Fas antibody following CYP2E1 induction in mice
- Expression of CYP2E1 by human monocyte‐derived macrophages
- CYP2E1 polymorphisms and gene–environment interactions in the risk of upper aerodigestive tract cancers among Indians
- NAT2, CYP2C9, CYP2C19, and CYP2E1 genetic polymorphisms in anti-TB drug-induced maculopapular eruption
- Role of CYP2E1 in the pathogenesis of alcoholic liver disease: modifications by cAMP and ubiquitin-proteasome pathway
- Spectrophotometric analysis of human CYP2E1-catalyzed p-nitrophenol hydroxylation
- Cervical cancer and CYP2E1 polymorphisms: implications for molecular epidemiology
- Inactivation of hepatic CYP2E1 by an epoxide of diallyl sulfone
- Insertion polymorphism of CYP2E1 and urinary N-methylformamide after N, N-dimethylformamide exposure in Japanese workers
- Effect of exposure to benzo [a] pyrene on SODs, CYP1A1/1A2-and CYP2E1 immunopositive proteins in the blood clam Scapharca inaequivalvis
- Ethanol-mediated transplacental induction of CYP2E1 in fetal rat liver
- Breaking self-tolerance toward cytochrome P4502E1 (CYP2E1) in chronic hepatitis C: possible role for molecular mimicry
- Cytochrome P450 2E1 (CYP2E1)-dependent production of a 37-kDa acetaldehyde–protein adduct in the rat liver
- Ethanol intake and ethanol-induced locomotion and locomotor sensitization in CYP2E1 knockout mice
- Associations between CYP2E1 promoter polymorphisms and plasma 1, 3-dimethyluric acid/theophylline ratios
- Genotype and allele frequencies of polymorphic cytochromes P450 CYP1A2 and CYP2E1 in Mexicans
- CYP1A1, CYP2E1, GSTM1, GSTT1, GSTP1, and TP53 polymorphisms: do they indicate susceptibility to chronic obstructive pulmonary disease and non-small-cell …
- Effects of dietary fat composition on activities of the microsomal ethanol oxidizing system and ethanol‐inducible cytochrome P450 (CYP2E1) in the liver of rats …
- Use of the CYP2E1 genotype and phenotype for the biological monitoring of occupational exposure to styrene
- In vivo and in vitro characterization of chlorzoxazone metabolism and hepatic CYP2E1 levels in African Green monkeys: induction by chronic nicotine treatment
- Proteasome inhibition potentiates CYP2E1‐mediated toxicity in HepG2 cells
- Effect of CYP2E1 gene deletion in mice on expression of microsomal epoxide hydrolase in response to VCD exposure
- Adenovirus-mediated expression of Cu/Zn-or Mn-superoxide dismutase protects against CYP2E1-dependent toxicity
- CYP2E1 G1532C, NQO1 Pro187Ser, and CYP1B1 Val432Leu polymorphisms are not associated with risk of squamous cell carcinoma of the head and neck
- CYP2E1 active site residues in substrate recognition sequence 5 identified by photoaffinity labeling and homology modeling
- Malotilate, a hepatoprotectant, suppresses CYP2E1 expression in rats
- Role of mouse CYP2E1 in the O-hydroxylation of p-nitrophenol: comparison of activities in hepatic microsomes from CYP2E1 (-/-) and wild-type mice
- Pulsatile blood alcohol and CYP2E1 induction during chronic alcohol infusions in rats
- … dehydrogenase 2, cytochrome p450 2E1 for liver cancer risk in HCV antibody-positive japanese patients and the variations of CYP2E1 mRNA expression levels in the …
- Use of CYP2E1‐transfected human liver cell lines in elucidating the actions of ethanol
- In vivo CYP2E1 phenotyping as a new potential biomarker of occupational and experimental exposure to benzene
- Induction of DNA strand breaks and oxidative stress in HeLa cells by ethanol is dependent on CYP2E1 expression
- Genetic polymorphisms of the CYP2E1 gene do not contribute to oral cancer susceptibility in south Indians
- Phenotype distribution and gender-related differences of CYP2E1 activity in a Chinese population
- Trimethadione metabolism by human liver cytochrome P450: evidence for the involvement of CYP2E1
- Influence of genetic admixture on polymorphisms of drug‐metabolizing enzymes: Analyses of mutations on NAT2 and CYP2E1 genes in a mixed Hispanic …
- Role of the proteasome complex in degradation of human CYP2E1 in transfected HepG2 cells
- Association Studies of Polymorphisms of CYP2E1 Gene in Alcoholics with Cirrhosis, Antisocial Personality, and Normal Controls
- Transcriptional and posttranscriptional regulation of CYP2E1, an N-nitrosodimethylamine demethylase.
- Association of CYP2E1, GST and mEH genetic polymorphisms with urinary acrylamide metabolites in workers exposed to acrylamide
- Green tea polyphenol epigallocatechin-3-gallate protects HepG2 cells against CYP2E1-dependent toxicity
- Chronic ethanol feeding potentiates Fas Jo2-induced hepatotoxicity: Role of CYP2E1 and TNF-α and activation of JNK and P38 MAP kinase
- Role of CYP2E1 in deramciclane metabolism
- S-adenosyl methionine protects ob/ob mice from CYP2E1-mediated liver injury
- The influence of genetic polymorphism of CYP2E1 on the development of alcohol liver cirrhosis
- p53 mutation spectrum in relation to GSTM1, CYP1A1 and CYP2E1 in surgically treated patients with non-small cell lung cancer.
- Evidence for a tissue-specific induction of cutaneous CYP2E1 by dexamethasone
- Involvement of CYP2E1 and carboxylesterase enzymes in vinyl carbamate metabolism in human lung microsomes
- Genetic Polymorphisms of CYP2E1 and Risk of Colorectal Adenomas in the Self Defense Forces Health Study
- CYP2E1 Rsa I/Pst I polymorphism and esophageal cancer risk: a meta-analysis based on 1,088 cases and 2,238 controls
- The effect of lycopene on the total cytochrome P450, CYP1A2 and CYP2E1
- Chlorzoxazone metabolism by winter flounder liver microsomes: evidence for existence of a CYP2E1-like isoform in teleosts
- Role of CYP2E1 in the mouse model of MPTP toxicity
- Genetic polymorphism of CYP2E1 and digestive tract alcohol damage among Polish individuals
- CYP2E1 genotyping in renal cell/urothelial cancer patients in comparison with control populations.
- Genetic polymorphisms of CYP2E1, GSTT1, GSTP1, GSTM1, ALDH2, and ODC and the risk of advanced precancerous gastric lesions in a Chinese population
- Transgenic plants of Petunia hybrida harboring the CYP2E1 gene efficiently remove benzene and toluene pollutants and improve resistance to formaldehyde
- Induction of CYP2B and CYP2E1 in precision-cut rat liver slices cultured in defined medium
- Glutathione depletion in CYP2E1-expressing liver cells induces toxicity due to the activation of p38 mitogen-activated protein kinase and reduction of nuclear factor-κB …
- Mammalian cytochrome CYP2E1 triggered differential gene regulation in response to trichloroethylene (TCE) in a transgenic poplar
- CYP2E1 polymorphism, cigarette smoking, p53 expression, and survival in non-small cell lung cancer: a long term follow-up study
- Short-term treatment with alcohols causes hepatic steatosis and enhances acetaminophen hepatotoxicity in CYP2E1 (-/-) mice
- Phosphorylation of cytochrome P4502E1 (CYP2E1) by calmodulin dependent protein kinase protein kinase C and cAMP dependent protein kinase
- PI3K inhibitors reverse the suppressive actions of insulin on CYP2E1 expression by activating stress-response pathways in primary rat hepatocytes
- In vitro metabolism of styrene to styrene oxide in liver and lung of CYP2E1 knockout mice
- Dietary lipids affect human ethanol-inducible CYP2E1 gene expression in vivo in mononuclear cells
- Independent and combined effects of ethanol self-administration and nicotine treatment on hepatic CYP2E1 in African green monkeys
- … of human prenatal biosynthesis of all-trans-retinoic acid by ethanol, ethanol metabolites, and products of lipid peroxidation reactions: a possible role for CYP2E1
- Gene Structure and Multiple Regulations of the Ethanol-Inducible Cytochrome P45O2E1 (CYP2E1) Subfamily
- Role of phospholipase A2 activation and calcium in CYP2E1-dependent toxicity in HepG2 cells
- Panax vietnamensis protects mice against carbon tetrachloride-induced hepatotoxicity without any modification of CYP2E1 gene expression
- Study on the association between genetic polymorphism of CYP2E1, GSTM1 and susceptibility of lung cancer
- A multiplex-PCR/RFLP procedure for simultaneous CYP2E1, mEH and GSTM1 genotyping
- Lycopene attenuates arachidonic acid toxicity in HepG2 cells overexpressing CYP2E1
- APOE and CYP2E1 polymorphisms, alcohol consumption, and Parkinson’s disease in a Japanese population
- Epoxide formation from diallyl sulfone is associated with CYP2E1 inactivation in murine and human lungs
- D2-receptor-linked signaling pathways regulate the expression of hepatic CYP2E1
- Metabolic activation of o-phenylphenol to a major cytotoxic metabolite, phenylhydroquinone: role of human CYP1A2 and rat CYP2C11/CYP2E1
- Expression and activity of CYP2E1 in circulating lymphocytes are not altered in diabetic individuals
- Modification effects of GSTM1, GSTT1 and CYP2E1 polymorphisms on associations between raw salted food and incomplete intestinal metaplasia in a high‐risk …
- Validation of 4-nitrophenol as an in vitro substrate probe for human liver CYP2E1 using cDNA expression and microsomal kinetic techniques
- Depression of glutathione content, elevation of CYP2E1-dependent activation, and the principal determinant of the fasting-mediated enhancement of 1, 3-dichloro-2 …
- Effects of acute renal failure induced by uranyl nitrate on the pharmacokinetics of intravenous theophylline in rats: the role of CYP2E1 induction in 1, 3‐dimethyluric …
- Effects of N-acetyltransferase 2 (NAT2), CYP2E1 and Glutathione-S-transferase (GST) genotypes on the serum concentrations of isoniazid and metabolites in …
- Opposite action of S-adenosyl methionine and its metabolites on CYP2E1-mediated toxicity in pyrazole-induced rat hepatocytes and HepG2 E47 cells
- No significant expression of CYP2E1 in rat liver stellate cells
- CYP2E1 and clinical features in alcoholics
- Comparison of chlorzoxazone one-sample methods to estimate CYP2E1 activity in humans
- Acetaminophen alters microsomal ryanodine Ca2+ channel in HepG2 cells overexpressing CYP2E1
- No Association between Polymorphisms in CYP2E1, GSTM1, NAT1, NAT2 and the Risk of Gastric Adenocarcinoma in the European Prospective Investigation into …
- The effect of isoniazid containing regimen on CYP2E1 during antituberculosis therapy.
- A Haplotype Analysis of CYP2E1 Polymorphisms in Relation to Alcoholic Phenotypes in Mexican Americans
- A reaction network model for CYP2E1-mediated metabolism of toxicant mixtures
- Ca2+-dependent and independent mitochondrial damage in HepG2 cells that overexpress CYP2E1
- Cytochrome b5 reductase and cytochrome b5 support the CYP2E1-mediated activation of nitrosamines in a recombinant Ames test
- Overexpression of CYP2E1 enhances sensitivity of hepG2 cells to fas-mediated cytotoxicity
- INFLUENCE OF GENETIC ADMIXTURE ON POLYMORPHISMS OF ALCOHOL-METABOLIZING ENZYMES: ANALYSES OF MUTATIONS ON THE CYP2E1, ADH2, ADH3 AND …
- Liver nuclear and microsomal CYP2E1-mediated metabolism of xenobiotics in rats chronically drinking an alcohol-containing liquid diet
- Effect of CYP2E1 induction by ethanol on the immunotoxicity and genotoxicity of extended low-level benzene exposure
- Role of nitric oxide and nuclear factor-κB in the CYP2E1 potentiation of tumor necrosis factor α hepatotoxicity in mice
- Identification of sequences responsible for intracellular targeting and membrane binding of rat CYP2E1 in yeast
- Suppression of cytochrome P450 2E1 promoter activity by interferon-γ and loss of response due to the-71G> T nucleotide polymorphism of the CYP2E1* 7B allele
- Identification and functional analysis of a novel human CYP2E1 far upstream enhancer
- Rifampicin suppresses hepatic CYP2E1 expression and minimizes DNA injury caused by carbon tetrachloride in perivenular hepatocytes of mice
- Inhibition of CYP2E1 activity does not abolish pulsatile urine alcohol concentrations during chronic alcohol infusions
- Molecular cloning and sequence analysis of hamster CYP2E1
- Relationship between genetic polymorphism of CYP2E1 and ALDH2, and possible susceptibility to alcoholism
- … mechanism of Wu-Zi-Yan-Zong-Wan, a traditional Chinese herbal formula, against alcohol-induced oxidative damage in CYP2E1 cDNA-transfected HepG2 (E47) …
- … overexpression of catalase in the cytosolic or mitochondrial compartment protects against toxicity caused by glutathione depletion in HepG2 cells expressing CYP2E1
- Effects of steady-state lasofoxifene on CYP2D6-and CYP2E1-mediated metabolism
- [12] Chlorzoxazone: An in vitro and in vivo substrate probe for liver CYP2E1
- CYP2E1-dependent bioactivation of 1, 1-dichloroethylene in murine lung: formation of reactive intermediates and glutathione conjugates
- Modulation of mouse P450 isoforms CYP1A2, CYP2B10, CYP2E1, and CYP3A by the environmental chemicals mirex, 2, 2-bis (p-chlorophenyl)-1, 1-dichloroethylene …
- Lack of cytochrome P450 2E1 (CYP2E1) induction in the rat liver by starvation without coprophagy
- Influence of GSTs, CYP2E1 and mEH polymorphisms on 1, 3-butadiene-induced micronucleus frequency in Chinese workers
- Influence of GSTT1, mEH, CYP2E1 and RAD51 polymorphisms on diepoxybutane-induced SCE frequency in cultured human lymphocytes
- Tightly regulated and inducible expression of rabbit CYP2E1 using a tetracycline-controlled expression system
- Striking LD50 variation associated with fluctuations of CYP2E1-positive cells in hepatic lobule during chronic CCl4 exposure in mice
- Expression of cytochrome P450 enzymes CYP1A1, CYP1B1, CYP2E1 and CYP4B1 in cultured transitional cells from specimens of the human urinary tract and from …
- Isozyme-selective metabolism of ethyl carbamate by cytochrome P450 (CYP2E1) and carboxylesterase (hydrolase A) enzymes in murine liver microsomes
- … of the accumulation of acetaldehyde from ethanol in human prenatal cephalic tissues: evaluation of the relative contributions of CYP2E1, alcohol dehydrogenase, and …
- CYP2E1 and CYP3A1/2 gene expression is not associated with the ursodeoxycholate effect on ethanol-induced lipoperoxidation
- CYP2E1 inhibition enhances mallory body formation
- XRCC1, CYP2E1 and ALDH2 genetic polymorphisms and sister chromatid exchange frequency alterations amongst vinyl chloride monomer-exposed polyvinyl …
- Cytochrome b5 coexpression increases the CYP2E1-dependent mutagenicity of dialkylnitrosamines in methyltransferase-deficient strains of Salmonella typhimurium
- Effect of disulfiram‐mediated CYP2E1 inhibition on the disposition of vesnarinone
- Nitric oxide donors prevent while the nitric oxide synthase inhibitor L-NAME increases arachidonic acid plus CYP2E1-dependent toxicity
- CYP2E1 overexpression inhibits microsomal Ca2+-ATPase activity in HepG2 cells
- Induction of brain CYP2E1 changes the effects of ethanol on dopamine release in nucleus accumbens shell
- The role of phosphatidylinositol 3-kinase, Src kinase, and protein kinase A signaling pathways in insulin and glucagon regulation of CYP2E1 expression
- Voglibose potentiates the hepatotoxicity of carbon tetrachloride and acetaminophen by inducing CYP2E1 in rats
- Administration of the tris salt of α-tocopheryl hemisuccinate inactivates CYP2E1, enhances microsomal α-tocopherol levels and protects against carbon tetrachloride …
- Influence of selected inhibitors on the metabolism of the styrene metabolite 4-vinylphenol in wild-type and CYP2E1 knockout mice
- Lack of common mutation in the alfa-subunit of the mitochondrial trifunctional protein and the polymorphism of CYP2E1 in three Japanese women with acute fatty liver …
- Induction of CYP1A1 and CYP2E1 in rat liver by histamine: binding and kinetic studies
- Cytochrome P4502E1 (CYP2E1) Genetic Polymorphisms in a Lebanese Population: Frequency Distribution and Association with Morbid Diseases
- CYP1A1 and CYP2E1 polymorphism frequencies in a large Brazilian population
- THE EFFECTS OF THE ALDH2*1/2, CYP2E1 C1/C2 AND C/D GENOTYPES ON BLOOD ETHANOL ELIMINATION
- Noninvolvement of CYP2E1 in the (ω-1)-hydroxylation of fatty acids in rat kidney microsomes
- Effect of total alkaloids of Rubus alceaefolius poiron on gene expressions of CYP2E1 and CYP3A1 in rats with acute liver injury
- Watercress has no importance for the elimination of ethanol by CYP2E1 inhibition
- Inhibition of rat hepatic CYP2E1 by quinacrine: molecular modeling investigation and effects on 4-(methyl nitrosamino)-1-(3-pyridyl)-1-butanone (NNK)-induced …
- Undernutrition during hyperoxic exposure induces CYP2E1 in rat liver
- Transcriptional activity of the tandem repeat polymorphism in the 5′‐flanking region of the human CYP2E1 gene
- Trifluoroacetylated adducts in spermatozoa, testes, liver and plasma and CYP2E1 induction in rats after subchronic inhalatory exposure to halothane
- A polymorphism in the 5′-flanking region of the CYP2E1 gene and elevated lung adenocarcinoma risk in a Japanese population
- Polymorphisms of the CYP1A1, CYP2E1 and XRCC1 genes and cancer risk in a Southern Italian population: a case–control study
- CYP2E1 level in rat liver injured by the interaction between carbon tetrachloride and chloroform
- Serum autoantibodies against cytochrome P450 2E1 (CYP2E1) predict severity of necroinflammation of recurrent hepatitis C
- Association of CYP2E1 of PON2311 polymorphisms in neonates with preterm
- Role of CYP2E1 in ketone-stimulated insulin release in pancreatic B-cells
- Relative roles of CYP2E1 and CYP1A2 in mouse uroporphyria caused by acetone
- Extrahepatic metabolism by CYP2E1 in PBPK modeling of lipophilic volatile organic chemicals: impacts on metabolic parameter estimation and prediction of dose …
- Use of Duplex PCR-CTPP Methods for CYP2E1 RsaI/IL-2 T-330G and IL-1B C-31T/TNF-A T-1031C Polymorphisms
- Examination of a CYP2E1 repeat polymorphism in a monkey model of alcohol abuse
- CYP2E1 overexpression up-regulates both non-specific δ-aminolevulinate synthase and heme oxygenase-1 in the human hepatoma cell line HLE/2E1
- Metabolism and toxicity of the styrene metabolite 4-vinylphenol in CYP2E1 knockout mice
- Protein kinase C signaling as a survival pathway against CYP2E1-derived oxidative stress and toxicity in HepG2 cells
- Urinary excretion of 6‐hydroxychlorzoxazone as an index of CYP2E1 activity
- Cloning and expression of rat CYP2E1 in Saccharomyces cerevisiae: Detection of genotoxicity of N‐alkylformamides
- Role of the Genetic Polymorphisms in the 5′‐Flanking Region for Transcriptional Regulation of the Human CYP2E1 Gene
- Role of polymorphic variants of cytochrome P450 genes (CYP1A1, CYP2E1) and microsomal epoxide hydrolase (mEPHX) in pathogenesis of cystic fibrosis and …
- Conformational anti‐cytochrome P4502E1 (CYP2E1) auto‐antibodies contribute to necro‐inflammatory injury in chronic hepatitis C
- Relation of GSTP1 and CYP2E1 polymorphisms with susceptibility to acute leukemia
- Decreased CYP2E1 mRNA expression in human leucocytes in patients with fibrotic and inflammatory lung diseases
- ALDH2 and CYP2E1 genotypes, urinary acetaldehyde excretion and the health consequences in moderate alcohol consumers
- The NH2-terminal region of rabbit CYP2E1 is not essential for interaction with NADPH-cytochrome P450 reductase
- Effect of high‐dose aspirin on CYP2E1 activity in healthy subjects measured using chlorzoxazone as a probe
- Genetic variation in the temperature dependence of liver microsomal CYP2E1 activity, within and between species of the viviparous fish Poeciliopsis
- Insertional polymorphism of the CYP2E1 gene in infiltrative pulmonary tuberculosis in populations of Bashkortostan Republic
- Cryopreserved porcine hepatocytes: expression and induction of cytochrome P450, isoform CYP2E1
- Comparison of levels of cytochromes P‐450, CYP1A2, CYP2E1, and their related monooxygenase activities in human surgical liver samples
- Modulation of ethanol-mediated CYP2E1 induction by clofibrate and L-carnitine in rat liver
- The effect of endotoxin on hepatocyte nuclear factor 1 nuclear protein binding: potential implications on CYP2E1 expression in the rat
- Effect of CYP2E1 polymorphism on DNA stability and lung cancer susceptibility
- Area Under the Plasma Concentration–Time Curve of Inorganic Fluoride Following Sevoflurane Anesthesia Correlates with CYP2E1 mRNA Level in Mononuclear …
- Identification of a 16-nucleotide sequence that mediates post-transcriptional regulation of rat CYP2E1 by insulin
- Fetal and maternal CYP2E1 genotypes and the risk of nonsyndromic oral clefts
- Bioactivation of 1, 1-dichloroethylene to its epoxide by CYP2E1 and CYP2F enzymes
- Exacerbation of benzene pneumotoxicity in connexin 32 knockout mice: enhanced proliferation of CYP2E1-immunoreactive alveolar epithelial cells
- Comparison of cytochrome P4502E1 (CYP2E1) activity and hepatic and lymphocyte mRNA expression in patients with chronic hepatitis C
- IL-4-mediated transcriptional regulation of human CYP2E1 by two independent signaling pathways
- Phorbol ester induces CYP2E1 in astrocytes, through a protein kinase C‐and tyrosine kinase‐dependent mechanism
- Role of phosphatidylinositol 3-kinase/AKT as a survival pathway against CYP2E1-dependent toxicity
- Polymorphism of the 5′‐Flanking Region of the CYP2E1 Gene: An Association Study With Alcoholism
- Activity of immobilised rat hepatic microsomal CYP2E1 using alumina membrane as a support
- Increased toxicity by transforming growth factor-beta 1 in liver cells overexpressing CYP2E1
- Isolation of the mouse cytochrome P450J (CYP2E1) cDNA and its reciprocal testosterone regulation in kidney and liver
- Hepatotoxicity Mediated by Pyrazole (CYP2E1) Plus TNF-α Treatment Occurs in jnk2−/− but not in jnk1−/− Mice
- A comparison of the inhibitory effects of four volatile anaesthetics on the metabolism of chlorzoxazone, a substrate for CYP2E1, in rabbits
- Contribution of the ALDH2 and CYP2E1 genes to flushing response and drinking patterns in Japanese healthy volunteers
- Assessment of frequencies of lifestyle factors and polymorphisms of drug-metabolizing enzymes (NAT2, CYP2E1) in human hepatocellular carcinoma (HCC) patients …
- Upregulation of CYP2E1 and cyp3a activities in histamine-deficient histidine decarboxylase gene targeted mice
- Low-dose diethyldithiocarbamate attenuates the hepatotoxicity of 1, 3-dichloro-2-propanol and selectively inhibits CYP2E1 activity in the rat
- Comparison of the polymorphic regions of the cytochrome P450 CYP2E1 gene of humans and patas and cynomolgus monkeys
- Cytochrome p-450-mediated differential oxidative modification of proteins: albumin, apolipoprotein E, and CYP2E1 as targets
- Activation of alkylhydrazines to free radical intermediates by ethanol-inducible cytochrome P-4502E1 (CYP2E1)
- Insertion Polymorphism of the CYP2E1 gene in patients with infiltrative pulmonary tuberculosis from Bashkortostan
- Dichloroacetic acid treatment increases hepatic CYP2E1 in male and female rats
- Altered ethylbenzene-mediated hepatic CYP2E1 expression in growth hormone-deficient dwarf rats
- Polymorphisms of the cytochrome P450 (CYP1A1, CYP2E1) and microsomal epoxide hydrolase (mEPHX) genes in cystic fibrosis and chronic respiratory disease
- … , Scrophularia ningpoensis, Asparagus cochinchinensis and Ophiopogon japonicas on contents of CYP450 and activities of CYP3A, CYP2E1 and CYP1A2 in rat
- Genetic regulation of liver microsomal CYP2E1 activity among strains of the viviparous fishes Poeciliopsis occidentalis and Poeciliopsis lucida
- Diminished CYP2E1 expression and formation of 2-S-glutathionyl acetate, a glutathione conjugate derived from 1, 1-dichloroethylene epoxide, in murine lung tumors
- Effect of 1-aminobenzotriazole on the in vitro metabolism and single-dose pharmacokinetics of chlorzoxazone, a selective CYP2E1 substrate in Wistar rats
- The genetic regulation of liver microsomal CYP2E1 activity among strains of the viviparous fish Poeciliopsis
- Bioactivation of 1, 1-dichloroethylene by CYP2E1 and CYP2F2 in murine lung
- Effects of chlorinated aliphatic hydrocarbons on the fidelity of cell division in human CYP2E1 expressing cells
- Abnormal liver function associated with polymorphism of GSTT1, GSTM1 and CYP2E1 in workers exposed to N, N-dimethylformamide
- CYP2E1–Biochemical and Toxicological Aspects and Role in Alcohol-Induced Liver Injury
- Case-control study of the polymorphisms of CYP2E1-RsaⅠ and STT1 genes and susceptibility to pancreatic cancer
- Genetic polymorphisms of alcohol inducible CYP2E1 in Turkish population
- Expression of human CYP2E1 in insect cells using bac-to-bac expression system
- A Case-control study on effects of genetic polymorphisms of GSTM1, GSTT1, CYP1A1 and CYP2E1 on risk of lung cancer
- Glucose inhibition of the induction of CYP2E1 mRNA expression by ethanol in FGC-4 cells
- Effect of methacrylonitrile on cytochrome P-450 2E1 (CYP2E1) expression in male F344 rats
- … of liver microsomal 7-ethoxycoumarin O-deethylation and chlorzoxazone 6-hydroxylation activities in Japanese and Caucasian subjects genotyped for CYP2E1 gene
- No linkage of the cytochrome P-450IIE1 (CYP2E1) C1/C2 polymorphism to schizophrenia
- Antibodies against CYP2E1 after exposure to 1, 1, 1-trifluoroethane and 1, 1, 1, 2-tetrafluoroethane
- Overexpression of CYP2E1 induces HepG2 cells death by the AMP kinase activator 5′-aminoimidazole-4-carboxamide-1-β-d-ribofuranoside (AICAR)
- Immunohistochemical Detection of CYP2E1 and 2-S-Glutathionyl Acetate in Murine Lung Tumors: Diminished Formation of Reactive Intermediates of 1,1 …
- CYP2E1 genotypes and serum LAP in Japanese alcoholics
- Genetic polymorphisms of CYP2E1
- Non-positive autoimmune responses against CYP2E1 in refrigeration mechanics exposed to halogenated hydrocarbons
- Development of a non-high pressure liquid chromatography assay to determine [14C] chlorzoxazone 6-hydroxylase (CYP2E1) activity in human liver microsomes
- The colorectal cancer risk of meat intake, smoking, and CYP2E1 polymorphisms: the comparison of colorectal cancer patients with controls
- Genetic Polymorphism of Alcohol Metabolizing Enzymes, CYP2E1
- Relationship between CYP2E1 polymorphism and increase of ALT activity during therapy of patients with pulmonary tuberculosis
- Halothane inhalation inhibits the metabolism of chlorzoxazone, a substrate for CYP2E1, in rabbits
- Analysis of CYP2E1 and GSTM1 polymorphisms for the determination of genetic susceptibility to Korean patients with colon cancer
- Inactivation of cytochrome P-450 (CYP2E1) and carboxylesterase (hydrolase A) enzymes by vinyl carbamate in murine pulmonary microsomes
- Antibiotic furazolidone induces CYP1A but not CYP2E1 subfamily in rat liver
- Effect of starvation and acetone on the enzyme systems of biotransformation and toxicity of xenobiotics–CYP2E1 substrates in rats
- Comparative analysis of binding affinities between styrene and mammalian CYP2E1 by bioinformatics approaches
- Study of the fragmentation mechanism of protonated 6-hydroxychlorzoxazone: application in simultaneous analysis of CYP2E1 activity with major human cytochrome …
- Gene CYP2E1 expression in mouse liver cells exposed to low-dose radiation
- Interaction of polymorphisms of CYP2E1 and environmental risk factors in gastric cancer
- Effect of Genetic Polymorphisms of CYP2E1 and ALDH2 on the Relationship between the Levels of Urinary 8-Hydroxydeoxyguanosine and t, t-Muconic Acid
- Trimethadione N-demethylation by rat liver CYP2E1 in vitro.
- Correlation analyses of ALDH2 and CYP2E1 genetic polymorphism with personality
- Variations in expression of CYP2E1 and COUP-TF1 proteins between Large White and Duroc cross-breeds
- GYKI-47261, a new AMPA [2-amino-3-(3-hydroxymethylisoxazole-4-yl) propionic acid] antagonist, is a CYP2E1 inducer
- Research on the relationship between ALDH2 and CYP2E1 gene polymorphism and alcoholic liver disease in Han people
- Differential expression of cytochrome P4502E1 (CYP2E1) in Morris hepatomas and livers of tumor bearing rats.
- A novel lipopolysaccharide‐modulated Jun binding repressor in intron 2 of CYP2E1
- Association analysis of alcohol metabolizing enzymes ADH1B, ADH7, CYP2E1 gene polymorphism with risk for coronary atherosclerosis
- Identification of polymorphisms in CYP2E1 gene and association analysis among chronic HBV patients
- Increase expression of CYP2E1 mRNA after methamphetamine administration in rats
- The role of CYP2E1 in the protection of garlic oil’s from n-hexane-induced neurotoxicity
- Pulmonary bioactivation of 1, 1-dichloroethylene is associated with CYP2E1 levels in A/J, CD-1, and C57BL/6 mice
- Ethanol-induction of cytochrome P450 2A5: permissive role for CYP2E1
- Characterization of a dietary ethanol protocol for CYP2E1 induction in the CD-1 mouse without evident hepatic toxicity or genotoxicity
- A decrease in S-adenosyl-L-methionine potentiates arachidonic acid cytotoxicity in primary rat hepatocytes enriched in CYP2E1
- Cytochemical Localization of the Acetone-lnducible Cytochrome P-450 Isoform, CYP2E1 in Murine Colonic Epithelium
- A study for regulation of ethanol-inducible P450 (CYP2E1) on CCl4-induced hepatic damage
- Associations of Rsa I polymorphism at the 5’flanking region of CYP2E1 and PON2 148 polymorphism in neonates with preterm delivery
- Effect of sulfur dioxide inhalation on CYP2B1/2 and CYP2E1 in rat liver and lung
- Genetic polymorphism of human CYP2E1: new allels detected in exons and exon-intron junctions
- Relationship between alcoholism and CYP2E1 genotypes
- A case control study on the impact of CYP2E1 and GST-M1 polymorphisms on the risk of lung cancer
- Preliminary effects of alcohol and Curcuma longa upon CYP2E1 and hematotoxicity in benzene-induced mice
- Association of genetic polymorphisms of aldehyde dehydrogenase II and CYP2E1 and clinical characteristics of patients with alcohol dependence
- Downregulation of the CYP2E1 ameliorates oxidative stress and apoptosis
- Interaction between genetic polymorphisms of CYP2E1 & NAT1 and smoking in lung cancer development (Preliminary report)
- Human CYP2E1 developmental expression: a role in fetal and pediatric susceptibility to toxicants?
- Effects of environmental carcinogens and genetic polymorphisms of CYP2E1 and NAT2 on gastric carcinogenesis
- Effects of Purified Glycerol from Biodiesel on Cyp1a1 and CYP2E1 Expressions in CBA/CA Mice
- Fast CYP2E1 genotyping using automated fluorescent detection.
- Association of CYP2E1, NQO1 and GST genetic polymorphisms with risk of acute lymphoblastic leukemia in turkish children
- Ruthenium red protects HepG2 cells overexpressing CYP2E1 against acetaminophen cytotoxicity
- CYP2E1 competes with CYP2B4 for limited NADPH‐Cytochrome P450 Reductase
- Expression and regulation of cytochrome P450 CYP2E1 in the minipig
- Effect of TFHL on expression of CYP2E1 in liver tissue of rats with NASH.
- Effects of ginsenoside Rd and Panax ginseng extract on Cyp1a, Cyp2b, Cyp2c, CYP2E1, and Cyp3a activities in C57BL/6JNarl mice
- The research on the relationship between CD44, CYP2E1 genetic polymorphisms and esophageal cancer
- Action-mechanisms of Genetic Polymorphism in the CYP2E1 on Susceptibility to Polycyclic Aromatic Hydrocarbons
- CYP1A1, CYP2E1 and gastric cancer risk in a high-incidence Colombian population
- Ontogeny of Rat CYP2E1 and CYP1A2: A Characterization and
- Effects of mitomycin (MMC) and {gamma}-ray irradiation on cytochrome p450 content and activities of CYP2B1 and CYP2E1 in rats
- The modeling of interactions of the CYP2E1 isoform of human cytochrome P450 with substrates
- Identification of CYP2E1-dependent genes involved in carbon tetrachloride-induced hepatotoxicity
- Evidence for the Existence of Two Human CYP2E1 cDNAs Using Different Polyadenylation Signals
- Functional polymorphism of CYP2E1 gene and alcohol use disorders in a Tibetan population.
- The ethanol elimination pharmacokinetics–the effects of genotypes of ALDH2 and CYP2E1 on the ethanol metabolism
- Differential expression profile of cytochrome p450 2E1 (CYP2E1) related genes associated with carbon tetrachloride-induced hepatotoxicity
- Effect of total saikosaponins on the intestinal first-pass effect and liver Cyp3a, CYP2E1
- Relationship between gene polymorphism of CYP2E1, CYP1A1, IL-4 and medicamentosa-like dermatitis induced by trichloroethylene
- High dose lycopene supplementation increases hepatic CYP2E1 protein and TNF‐α expression in alcohol fed rats
- The ethanol elimination pharmacokinetics–the effects of genotypes of ALDH2 and CYP2E1 on the ethanol metabolism
- Silibinin inhibits CYP2E1‐dependent ethanol metabolism, oxidative stress and cell proliferation in a rat model of hepatocellular carcinoma (HCC)
- Opposite effects of isoniazid and fasting on the expression of CYP2E1 protein and mRNA in house musk shrew (Suncus murinus)
- Computational docking studies of nitroanisoles and nitrophenols with CYP2E1
- ALDH and CYP2E1 Single Nucleotide Polymorphism Distribution in Korean
- Role of CYP2E1 in Hepatocarcinogenesis and Hepatotoxicity
- An investigation of CYP2E1 phenotype determination utilizing modeling and simulation studies
- Formation of Multiple CYP2E1 Complexes Affects Activity
- Regulation of CYP2E1 and Tissue Protection Effect of CYP2E1 Inhibitor
- Mapping of pig CYP2E1 to SSC14
- ALDH and CYP2E1 Single Nucleotide Polymorphism Distribution in Korean
- CYP2E1 mutation associated with increased chlorzoxazone (CZ) metabolic ability
- Alcohol, Nicotine and Genetic Variation Influence CYP2E1
- Different CYP2E1 genotypes and alcoholic liver disease.
- Establishment and toxicological application of a cell line expressing human CYP2E1
- The Toxicological Mechanism Of Styrene In CYP2E1 Transgenic Cells
- Effect of CYP2E1 Ras I genotypes on CYP2E1 enzyme activity and DNA damage induced by phenol in immortalized human lymphocytes
- Effects of environmental factors on extrahepatic CYP2E1 gene expression in mice
- Molecular Evidence for the Presence of CYP2E1 Retropseudogene in Human Genome
- Role Of Mouse CYP2E1 In The O-Hydroxylation Of P-Nitrophenol: Comparison Of Activities In CYP2E1 (-/-) And Wildtype Mice
- Structure-functional characterization of cytochrome P4502E1 (CYP2E1)
- Establishment of model with exogenous human CYP2E1 expression and inducement of substrates
- Chlorzoxazone as a Single Sample Probe of Hepatic CYP2E1 Activity
- A relationship between genetic polymorphisms of CYP2E1 and susceptibility of acute leukemia in Gansu population
- Application of a map Bayesian method for CYP2E1 phenotyping
- Role of CYP2E1 Immunoglobulin G4
- Individual variability of CYP2E1 xenobiotic oxidation in human liver
- The genotype of CYP2E1 and liver-derived serum enzymes
- A-71G> T Nucleotide Substitution uncouples IFN-[gamma]-dependent Suppression of CYP2E1 mRNA
- Pathogenesis of nonalcoholic steatohohepatitis [sic]: the role of CYP2E1
- Hormonal regulation of CYP2E1 and CYP2C11 in rat liver and kidney
- Inhibition of Ethanol-induced CYP2E1 by Curcuma longa L. Extract
- Immunological detection of CYP2E1 in the fresh lymphocytes
- THE EFFECT OF COPROPHAGY ON THE EXPRESSION OF HEPATIC CYP2E1 DURING STARVATION
- Effects of Danshen and Its Active Components on Rat CYP2E1 Expression and Metabolism of Model CYP2E1 Probe Substrate
- Construction of CYP2E1 recombinant adenovirus vector and its anti-tumor effects
- CYP2E1-DEPENDENT BIOACTIVATION OF 191
- Role Of Cytochrome P450 2E1 (CYP2E1) In Trichloroethylene (TCE) Metabolism And Disposition: Comparative Studies Using CYP2E1-/-And Wild-Type Mice
- The role of CYP2E1 and CYP4A in the development of non-alcoholic steatohepatitis
- CYP2E1 VNTR polymorphisms and hepatocarcinoma: a gender-specific correlation
- Substrate inhibition of CYP2E1 activity is primarily determined by lipophilicity
- Expression of CYP2E1 gene in liver tissue in patients with hepatic cirrhosis and obstuctive jaundice
- Study on the association between CYP2E1 enzymes and susceptibility of alcoholic liver disease
- An investigation of the induction of hepatic CYP2E1 by low doses of nicotine in the rat.
- The Effects of CYP2E1 and CYP2C19 Polymorphisms on the Susceptibility for Gastric Cancer
- Time-coursed Changes of CYP2E1 Protein in Acute Liver Injury by a Single CCI₄ Administration in SD Rats
- Search for possible changes in murine gene CYP2E1 structural region under exposure to ionizing radiation
- MAPPING CONFORMATIONAL CYP2E1 EPITOPES RECOGNISED BY AUTO-ANTIBODIES IN HALOTHANE HEPATITIS AND ALCOHOLIC LIVER DISEASE
- The Genetic Polymorphism of CYP2E1 in a Korean Healthy Subjects and Hepatocellular Carcinoma Patients
- Associations between CYP2E1 promoter polymorphisms and plasma 1, 3-dimethyluric acid/theophylline ratio
- CYP2E1 Genetic Polymorphism relating to Styrene Metabolism of Korean Workers
- Pharmacokinetics of drug interactions due to ligand stabilization of CYP2E1
- Determination of the activity of human hepatic cytochromes P450 CYP2C8/9, CYP2E1
- ALLELIC VARIANTS OF CYP2E1 GENE IN HEPATOCARCINOMA PATIENTS AND IN HEPATIC TUMOR CELL LINES
- e0048 CYP2E1 increases oxidative stress and induces apoptosis of cardio myocytes in transgenic mice
- Catalytic activity and quantitation of CYP2E1 in human embryonic and fetal brain tissues
- Various Fatty Acids Induce Cell Damages Differently in CYP2E1-transduced HepG2 Cells, E47 Cells, Compared to C34 Cells
- Polymorphisms of ADH2, ALDH2 and CYP2E1 in huichol and Mestizo subjects from western México in comparison with other populations of the world
- Cloning and sequence analysis of human embryonic nasopharyngeal epithelial CYP2E1 cDNA
- The influence of Jiuganning decoction on the content of CYP2E1 and cytokine IL-6, TNF in rats models of alcoholic hepatic injury
- Identification of a critical CYP2E1 epitope in patients with drug-induced liver injury from anesthetics (93.16)
- Experimental study on effect of Erchen decoction and Taohongsiwu decoction on CYP2E1 activities in non-alcoholic fatty liver rats
- Use of Cytochrome P450 2E1 (CYP2E1) Knockout Transgenic Mouse Model to Study the Role of CYP2E1 in Carbon Tetrachloride-and Alcohol-mediated …
- The role of CYP2A6 and CYP2E1 in the metabolism of 3-methylindole in porcine hepatocytes.
- Role of CYP2E1 in Impaired Nitric Oxide Synthase (NOS)‐Dependent Cerebral Vasodilation During Chronic Alcohol Consumption
- Increased citrate levels in non-alcoholic steatohepatitis: effect on CYP2E1
- The Role of CYP2E1 IgG4 Subclass Autoantibodies in the Development of Anesthetic Sensitization
- Cutaneous CYP2E1 induction after topical treatment by dexamethasone, ethanol and salicylic acid in mouse.
- Meta-analysis on relationship between polymorphisms of CYP2E1 gene and susceptibility to antituberculosis drug-induced liver injury
- Modulation of Murine CYP2E1 Activity by Disulfiram on Trichloroethylene-Induced Neurotoxicity A Pilot Study
- Chlormethiazole, an inhibitor of CYP2E1, prevented chemical carcinogen-initiated and alcohol-promoted hepatic carcinongenesis in rats.
- Single Nucleotide Polymorphisms in the Non-coding region of CYP2E1 among Koreans
- The Effects of Poly IC and Human Interferon ɑ on Rat Hepatic Cyp4a1 and CYP2E1
- Inhibition of Urethane-Induced Carcinogenicity in CYP2E1-/-Vs. CYP2E1+/+ Mice
- Polymorphism of CYP2E1 gene and the risk of lung cancer among African-Americans and Caucasians in Los Angeles County (California).
- Association of the blood biochemical index with CYP2E1 5’flanking region Rsa I/Pst I gene polymorphism and alcohol consumption habit in Southern Taiwan …
- The Effects of Chungganhaeju-tang(Qingganjiejiu-tang) on Alcohol induced Cytotoxicity in CYP2E1-transfected HepG2 cells.
- Investigation of indazole unbinding pathways in CYP2E1 by molecular dynamics simulations
- CYP2E1: Mechanism of induction by isoniazid and role in acetaminophen oxidation
- The relationship between the GST T1, GST M1, CYP2E1 genotype and abnormal liver function in PVC workers
- Analyses of Mutation Frequency on the CYP2E1, ADH2, and ALDH2 Genes among Five Ethnic Groups
- Molecular Regulation of Ethanol-inducible P450 (CYP2E1) in Acute CCI₄Treatment
- CYP2E1-dependent bioactivation of 1, 1-dichloroethylene to reactive intermediates in murine and human lung and liver microsomes.
- CYP2E1 Mediates Ethanol-Induced DNA Damage And TNF Release In Bronchial Epithelial Cells
- Oral clefts, maternal exposure to solvents and CYP2E1 polymorphism
- Effect of γ-irradiation and mitomycin C (MMC) on CYP2B1 and CYP2E1 activities in rat hepatic microsomes in vitro
- The Effects of CYP2E1 on Hepatic Gene Expression in 129/Sv-CYP2E1^ tm1Gonz/J and 129S1/SvImJ Mice Exposed to Hydrazine
- Variable Number of Tandem Repeats (VNTR) gene polymorphism of CYP2E1 in patients with pancreatic adenocarcinoma
- THE EFFECT OF ETHANOL ON COUMARIN METABOLISM AND CYTOTOXICITY IN TRANSFECTED CULTURES OF HEPG2 CELLS WITH CYP2E1 EXPRESSION.
- Cytochrome P450 2E1 (CYP2E1) Induction By Pyridazine Produces Qualitative And Quantitative Changes In The Metabolism Of Trichloroethylene To Potentially …
- Inhibition of B12‐dependent methionine synthase activity in HepG2 cells over‐expressing CYP2E1
- Overexpression of CYP2E1 Increases Sensitivity of HepG2 Cells to Isoniazid-Induced Cytotoxicity
- Relation between genetic polymorphisms of ADH, CYP2E1, GSTP1 and their expression in Caucasian lung tissue
- Detection of autoantibodies against cytochrome P450 2E1 (CYP2E1) in patients with recurrent hepatitis C
- Association of GSTM1, P1, T1 and CYP2E1 Single Nucleotide Polymorphisms with Colorectal Cancer in Iran: 391
- Lack of correlation between lymphocytic mrna expression and activity of CYP3A4 and CYP2E1 In‐vivo in alcoholics and non‐alcoholics
- RELATIONSHIPS BETWEEN GENETIC POLYMORPHISMS IN CYP2D6 AND CYP2E1 GENES AND LIVER MICROSOMAL DRUG OXIDATION ACTIVITIES
- NADPH: CYTOCHROME P450 REDUCTASES OF VARIOUS SPECIES CAN BE USED IN SYSTEMS RECONSTITUTING DRUG-METABOLIZING CYP2E1 …
- Single nucleotide polymorphisms and variable number of tandem repeat polymorphism of CYP2E1 in Koreans
- Strain-related Differences in CYP2E1 Levels are Associated with Differential Bioactivation of 1, 1-dichloroethylene in Murine Lung and Liver
- Inductive Effect Of Pyridazine (Pz) On Cytochrome P4502E1 (CYP2E1) Alters The Metabolism Of Trichloroethylene (TCE)
- Interactive effects between genetic polymorphisms of CYP2E1 & NAT1 and smoking on the development of lung cancer in Korean
- RELATIONSHIPS BETWEEN GENETIC POLYMORPHISMS IN CYP2D6 AND CYP2E1 GENES AND LIVER MICROSOMAL DRUG OXIDATION ACTIVITIES-STUDIES …
- AhR Mediated Hematotoxicity Is Induced At The Site Of Bone Marrow Where Consequent CYP2E1-Derived Benzene Metabolites Locally Induce Their Toxicity
- The potent protective effect of red ginseng against acetaminophen-induced toxicity through metabolic regulation of CYP2E1 and GSTs
- CYP2E1 overexpression up-regulates both non-specific ô-aminolevulinate synthase and heme oxygenase-1 in the human hepatoma cell line HLE/2E1
- Effects of CYP Inducers and Inhibitors on the Furosemide Pharmacokinetics: Involvement of CYP2E1 and 3A 1/2 for the Furosemide Metabolism
- Effect of tobacco smoke on the expression of Cyp1a, Cyp2b, Cyp2e, and Cyp3a subfamilies in mice. Possible role of CYP2E1 in pulmonary DNA single strand breaks …
- Proteomics of oxidative stress using inducible CYP2E1 expressing HEPG2 cells and 3T3-L1 adipocytes as model systems
- An estimate of polymorphism of ADH1B, ALDH2, and CYP2E1 alcohol biotransformation genes in Siberian indigenous and immigrant populations
- Effects of in vivo hepatic ischemia‐reperfusion injury on the CYP2E1‐mediated metabolism of chlorzoxazone and biliary clearance of its metabolite in isolated …
- Assessment of the role of cytochrome P450 2E1 (CYP2E1)-mediated metabolism in urethane-induced cell proliferation and gene expression: Biomarkers of …
- Effect of the South African traditional meat, biltong, on cancer-associated enzymes CYP2E1 and CYP1A2
- … of twelve chlorinated aliphatic hydrocarbons upon the cell cycle of Chinese hamster cell lines: V79d-MZ and genetically engineered cell lines expressing CYP2E1
- Association of the CYP2E1, FMO3, NQO1, GST, NOS3 genetic polymorphisms with ischemic stroke risk in Turkish population
- Alkyl sulfides Potentiation of Carbon Tetrachloride-induced Hepatotoxicity: The Role of CYP2E1 Expression
- The influence of alcohol on acetaminophen hepatotoxicity: CYP2E1 induction and selective mitochondrial glutathione depletion
- Interaction of genetic polymorphisms of glutathione S-transferase (GST) M1, GSTT1, and CYP2E1 in development of lung cancer
- A dietary ethanol protocol for CYP2E1 induction in CD-1 mice and its application to studies on the genotoxicity, immunotoxicity and metabolism of low-level benzene
- Genetic Polymorphism of CYP2E1, GSTT1/M1 and NQO1 on Biomarker of Urinary Spma Among Benzene-Exposed Workers
- A Composition of Metadoxine and Garlic Oil Abrogates Alcoholic Steatosis and CYP2E1 Induction in Rat Liver with AMPK Restoration
- The Association between Pneumoconiosis and Genetic Polymorphism of GSTM1, GSTT1, GSTP1, NAT2, CYP2E1 and CYP1A1
- The effect of trans-resveratrol analogues on the catalytic activities of CYP1A2 and CYP2E1 in mouse liver microsomes in vitro
- Genetic Polymorphisms of NAT2, CYP2C9, CYP2C19, CYP2D6 and CYP2E1, and Antituberculosis Drugs Induced Maculopapular Eruption
- Alterations in toxicokinetics of trichloroethylene (TCE) and trichloroacetic acid (TCA) due to cytochrome P450 2E1 (CYP2E1) induction
- The Role of Genetic Polymorphisms of CYP2E1, CYP1A1, NAT1, and NAT2 in Bladder Cancer in Korea
- Effects of benzene on liver, kidney and lung cyp1a, cyp2b4, CYP2E1 and cyp3a6 mrna, protein level, and drug metabolizing enzyme activities and toxicity in diabetic …
- Diphenyl-Dimethyl-Dicarboxylate Inhibits Carbon tetrachloride-induced Increase Kupffer Cell Counts in the Absence of CYP2E1 Suppression in the Rat
- Diallyl Sulfone, a Derivative of Garlic, Inactivates the Cytochrome P450 Enzyme CYP2E1 by Forming N-alkylprotoporphyrin Heme Adducts
- EFFECTS OF STRUCTURALLY AND FUNCTIONALLY DIVERSE GROUP OF PHYTOCHEMICALS ON ANILINE HYDROXYLATION (CYP2E1) OF CONTROL AND …
- … Cytochrome P450 Reductase-null Mice as an Animal Model to Study Electron Transfer Pathways in Cholesterol Synthesis and CYP2E1-mediated Drug Metabolism
- MATERNAL SMOKING, POLYMORPHISMS IN CYP1A1, CYP2E1, EPHX1, NAT2, NQO1, AND CHILDHOOD ACUTE LEUKEMIA
- Evaluation of influence of Andrographis paniculata on activities of CYP1A2, CYP3A4, CYP2E1 and CYP2C19 genotypes in chickens by multiple cytochrome P450 …
- Saponins Isolated from the Root of Platycodi Radix Abrogates Alcoholic Steatosis and CYP2E1 Induction in Rat Liver with Restoration of AMPK Activity
- Relationship between genetic polymorphisms of drug-metabolizing enzymes (CYP1A1, CYP1B1, CYP2E1, GSTM1, GSTT1, and NAT2) and p53 gene point mutations …
- Identification of 2‐Piperidone as a Biomarker of CYP2E1 Activity through Metabolomic Phenotyping
- The effects of the ALDH2* 1/2, CYP2E1 c1/c2 and C/D genotypes on blood ethanol elimination and the human serotonin receptor (HTR2) gene Msp1 polymorphism in …
- Elimination rate of 6-hydroxychlorzoxazone in urine as a non-invasive evaluation of cytochrome CYP2E1 activity. Lack of relationship to smoking
- IL-4 promotes experimental drug-induced hepatitis by reducing immune responses to haptenated proteins and inhibiting regulatory responses to native CYP2E1 …
- Computational Docking Investigations of Oxidative Metabolism of 4-Nitroanisole with CYP2E1
- CYP2E1 and oxidant stress in alcoholic and non-alcoholic fatty liver disease
- The role of CYP2E1 in alcohol metabolism and sensitivity in the central nervous system
- The Role of CYP2E1 in the Drug Metabolism or Bioactivation in the Brain
- Critical role of cytochrome P450 2E1 (CYP2E1) in the development of high fat-induced non-alcoholic steatohepatitis
- Regulation of the effects of CYP2E1-induced oxidative stress by JNK signaling
- New insight and potential therapy for NAFLD: CYP2E1 and flavonoids
- A systematic evaluation of microRNAs in regulating human hepatic CYP2E1
- Cytochrome P450 2E1 (CYP2E1) regulates the response to oxidative stress and migration of breast cancer cells
- CYP2E1 potentiates binge alcohol-induced gut leakiness, steatohepatitis, and apoptosis
- Induction of CYP2E1 in non-alcoholic fatty liver diseases
- Molecular dynamics simulations of CYP2E1
- Morbidly obese patients exhibit increased CYP2E1-mediated oxidation of acetaminophen
- CCl4-induced hepatotoxicity: protective effect of rutin on p53, CYP2E1 and the antioxidative status in rat
- Intestinal CYP2E1: A mediator of alcohol-induced gut leakiness
- Higher CYP2E1 activity correlates with hepatocarcinogenesis induced by diethylnitrosamine
- CYP2E1 autoantibodies in liver diseases
- Role of CYP2E1 in mitochondrial dysfunction and hepatic injury by alcohol and non-alcoholic substances
- CYP2E1 in alcoholic and non-alcoholic liver injury. Roles of ROS, reactive intermediates and lipid overload
- Impairment of Akt activity by CYP2E1 mediated oxidative stress is involved in chronic ethanol-induced fatty liver
- Induction of brain CYP2E1 by chronic ethanol treatment and related oxidative stress in hippocampus, cerebellum, and brainstem
- Ethanol induction of CYP2A5: role of CYP2E1-ROS-Nrf2 pathway
- Ethanol‐induced oxidative stress via the CYP2E1 pathway disrupts adiponectin secretion from adipocytes
- Association of NAT2, GST and CYP2E1 polymorphisms and anti-tuberculosis drug-induced hepatotoxicity
- Drug targeting CYP2E1 for the treatment of early-stage alcoholic steatohepatitis
- Autophagy protects against CYP2E1/chronic ethanol-induced hepatotoxicity
- NF-κB-mediated regulation of rat CYP2E1 by two independent signaling pathways
- The effect of quercetin on the pharmacokinetics of chlorzoxazone, a CYP2E1 substrate, in healthy subjects
- Downregulation of CYP2E1 is associated with poor prognosis and tumor progression of gliomas
- Methodology to assay CYP2E1 mixed function oxidase catalytic activity and its induction
- … psychosocial deprivation in early childhood is associated with increased DNA methylation across a region spanning the transcription start site of CYP2E1
- Nrf2 and antioxidant defense against CYP2E1 toxicity
- Role for intestinal CYP2E1 in alcohol-induced circadian gene-mediated intestinal hyperpermeability
- MicroRNA regulation of CYP 1A2, CYP3A4 and CYP2E1 expression in acetaminophen toxicity
- Plasma exosomes exacerbate alcohol-and acetaminophen-induced toxicity via CYP2E1 pathway
- Antioxidant and pro-oxidant mechanisms of (+) catechin in microsomal CYP2E1-dependent oxidative stress
- Pioglitazone, quercetin and hydroxy citric acid effect on cytochrome P450 2E1 (CYP2E1) enzyme levels in experimentally induced non alcoholic steatohepatitis …
- Chronic alcohol intake-induced oxidative stress and apoptosis: role of CYP2E1 and calpain-1 in alcoholic cardiomyopathy
- Mouse spermatocytes express CYP2E1 and respond to acrylamide exposure
- Toward a systems approach to cytochrome P450 ensemble: interactions of CYP2E1 with other P450 species and their impact on CYP1A2
- Period1 mediates rhythmic metabolism of toxins by interacting with CYP2E1
- Involvement of CYP2E1-ROS-CD36/DGAT2 axis in the pathogenesis of VPA-induced hepatic steatosis in vivo and in vitro
- Sulforaphane induces Nrf2 and protects against CYP2E1-dependent binge alcohol-induced liver steatosis
- Placental DNA methylation levels at CYP2E1 and IRS2 are associated with child outcome in a prospective autism study
- Estrogen-related receptor γ controls hepatic CB1 receptor-mediated CYP2E1 expression and oxidative liver injury by alcohol
- CYP2E1-dependent elevation of serum cholesterol, triglycerides, and hepatic bile acids by isoniazid
- Protective effects of taraxasterol against ethanol-induced liver injury by regulating CYP2E1/Nrf2/HO-1 and NF-κB signaling pathways in mice
- Inhibition of autophagy promotes CYP2E1-dependent toxicity in HepG2 cells via elevated oxidative stress, mitochondria dysfunction and activation of p38 and …
- CYP2E1 potentiates toxicity in obesity and after chronic ethanol treatment
- Protective effects of diallyl disulfide against acetaminophen-induced nephrotoxicity: a possible role of CYP2E1 and NF-κB
- Low doses of curcumin protect alcohol-induced liver damage by modulation of the alcohol metabolic pathway, CYP2E1 and AMPK
- Toxicological implications of mitochondrial localization of CYP2E1
- Alcoholic liver disease: from CYP2E1 to CYP2A5
- Investigation of indazole unbinding pathways in CYP2E1 by molecular dynamics simulations
- CYP2E1, GSTM1 and GSTT1 genetic polymorphisms and susceptibility to antituberculosis drug‐induced hepatotoxicity: a nested case–control study
- Sex steroid hormones regulate constitutive expression of CYP2E1 in female mouse liver
- Antioxidant Properties of Proanthocyanidins Attenuate Carbon Tetrachloride (CCl4)–Induced Steatosis and Liver Injury in Rats via CYP2E1 Regulation
- … effect of acidic polysaccharide from Schisandra chinensis on acute ethanol-induced liver injury through reducing CYP2E1-dependent oxidative stress
- Antioxidant Peptides from Protein Hydrolysate of Microalgae Navicula incerta and their Protective Effects in Hepg2/CYP2E1 Cells Induced by Ethanol
- Genetic Polymorphisms of Genes Coding to Alcohol‐Metabolizing Enzymes in Western Mexicans: Association of CYP2E1*c2/CYP2E1*5B Allele with Cirrhosis and …
- Ethanol-induced oxidative stress is associated with EGF receptor phosphorylation in MCF-10A cells overexpressing CYP2E1
- Role and importance of polymorphisms with respect to DNA methylation for the expression of CYP2E1 enzyme
- Prenatal antidepressant exposure associated with CYP2E1 DNA methylation change in neonates
- Potential pathogenetic link between angiomyofibroblastoma and superficial myofibroblastoma in the female lower genital tract based on a novel MTG1-CYP2E1 fusion
- CYP2E1 epigenetic regulation in chronic, low-level toluene exposure: Relationship with oxidative stress and smoking habit
- The association between CYP2E1 polymorphisms and hepatotoxicity due to anti-tuberculosis drugs: a meta-analysis
- Binge alcohol promotes hypoxic liver injury through a CYP2E1–HIF-1α-dependent apoptosis pathway in mice and humans
- Apigenin protects against alcohol-induced liver injury in mice by regulating hepatic CYP2E1-mediated oxidative stress and PPARα-mediated lipogenic gene …
- Kaempferol protects against propacetamol-induced acute liver injury through CYP2E1 inactivation, UGT1A1 activation, and attenuation of oxidative stress …
- CYP2E1 metabolism of styrene involves allostery
- ROS generated by CYP450, especially CYP2E1, mediate mitochondrial dysfunction induced by tetrandrine in rat hepatocytes
- Sex‐dependent regulation of cytochrome P450 family members Cyp1a1, CYP2E1, and Cyp7b1 by methylation of DNA
- The WNT/β-catenin pathway is a transcriptional regulator of CYP2E1, CYP1A2, and aryl hydrocarbon receptor gene expression in primary human hepatocytes
- Inhibition of CYP2E1 attenuates chronic alcohol intake-induced myocardial contractile dysfunction and apoptosis
- Association of CYP2E1 gene polymorphisms with bladder cancer risk: A systematic review and meta-analysis
- CYP2E1 regulates the development of radiation-induced pulmonary fibrosis via ER stress-and ROS-dependent mechanisms
- CYP2E1*5B, CYP2E1*6, CYP2E1*7B, CYP2E1*2, and CYP2E1*3 Allele Frequencies in Iranian Populations
- Effect of status epilepticus and antiepileptic drugs on CYP2E1 brain expression
- Investigating the CYP2E1 potential role in the mechanisms behind INH/LPS-induced hepatotoxicity
- Enantioselective metabolism of phenylpyrazole insecticides by rat liver microsomal CYP3A1, CYP2E1 and CYP2D2
- CYP2E1 changes the biological function of gastric cancer cells via the PI3K/Akt/mTOR signaling pathway
- CYP2E1 hydroxylation of aniline involves negative cooperativity
- Salidroside protects mice against CCl4-induced acute liver injury via down-regulating CYP2E1 expression and inhibiting NLRP3 inflammasome activation
- Refined CYP2E1∗ Template∗∗ system to decipher the ligand-interactions
- Functional PstI/RsaI Polymorphism in CYP2E1 Is Associated with the Development, Progression and Poor Outcome of Gastric Cancer
- CYP2E1 RsaI/PstI polymorphism and risk of anti-tuberculosis drug-induced liver injury: a meta-analysis
- Toward a systems approach to the human cytochrome P450 ensemble: interactions between CYP2D6 and CYP2E1 and their functional consequences
- Effect of ammonium pyrrolidine dithiocarbamate (PDTC) on NF-κB activation and CYP2E1 content of rats with immunological liver injury
- Prilocaine-and lidocaine-induced methemoglobinemia is caused by human carboxylesterase-, CYP2E1-, and CYP3A4-mediated metabolic activation
- CYP2E1 sensitizes the liver to LPS-and TNF α-induced toxicity via elevated oxidative and nitrosative stress and activation of ASK-1 and JNK mitogen …
- Induction of SIRT1 by melatonin improves alcohol‐mediated oxidative liver injury by disrupting the CRBN‐YY1‐CYP2E1 signaling pathway
- Human CYP2A6, CYP2B6, and CYP2E1 atropselectively metabolize polychlorinated biphenyls to hydroxylated metabolites
- Why hepatic CYP2E1-elevation by itself is insufficient for inciting NAFLD/NASH: Inferences from two genetic knockout mouse models
- Amalgamation of in-silico, in-vitro and in-vivo approach to establish glabridin as a potential CYP2E1 inhibitor
- Roles of CYP2E1 in 1, 2‐dichloroethane‐induced liver damage in mice
- High CYP2E1 activity correlates with hepatofibrogenesis induced by nitrosamines
- Baicalin ameliorates liver injury induced by chronic plus binge ethanol feeding by modulating oxidative stress and inflammation via CYP2E1 and NRF2 in …
- Relevance of CYP2E1 to non-alcoholic fatty liver disease
- Higher sensitivity of female cells to ethanol: methylation of DNA lowers CYP2E1, generating more ROS
- Protective effects of protein hydrolysate from marine microalgae Navicula incerta on ethanol-induced toxicity in HepG2/CYP2E1 cells
- Single-nucleotide polymorphisms in cytochrome P450 2E1 (CYP2E1) 3′-untranslated region affect the regulation of CYP2E1 by miR-570
- CYP2E1 polymorphisms and nasopharyngeal carcinoma risk: a meta-analysis
- The importance of CYP2E1 in the pathogenesis of alcoholic liver disease and drug toxicity and the role of the proteasome
- Genetic polymorphism analysis of cytochrome P4502E1 (CYP2E1) in a Chinese Tibetan population
- Glycyrrhetinic acid prevents acetaminophen-induced acute liver injury via the inhibition of CYP2E1 expression and HMGB1-TLR4 signal activation in mice
- Polydatin protects rat liver against ethanol-induced injury: involvement of CYP2E1/ROS/Nrf2 and TLR4/NF-B p65 pathway
- CYP2E1 in the human retinal pigment epithelium: expression, activity, and induction by ethanol
- Relationship of anti-tuberculosis drug-induced liver injury and genetic polymorphisms in CYP2E1 and GST
- Effect of piperine on CYP2E1 enzyme activity of chlorzoxazone in healthy volunteers
- … final hydrogenated metabolites of curcumin, possess superior hepatic-protective effect against acetaminophen-induced liver injury: role of CYP2E1 and Keap1-Nrf2 …
- Genetic Variability in CYP2E1 and Catalase Gene Among Currently and Formerly Alcohol-Dependent Male Subjects
- CYP2E1 induction leads to oxidative stress and cytotoxicity in glutathione-depleted cerebellar granule neurons
- Subcellular localization of rat CYP2E1 impacts metabolic efficiency toward common substrates
- Contributing roles of CYP2E1 and other cytochrome P450 isoforms in alcohol-related tissue injury and carcinogenesis
- Stat4 rs7574865 polymorphism promotes the occurrence and progression of hepatocellular carcinoma via the Stat4/CYP2E1/FGL2 pathway
- Effects of acrylamide on oxidant/antioxidant parameters and CYP2E1 expression in rat pancreatic endocrine cells
- CYP2E1 polymorphisms and colorectal cancer risk: a HuGE systematic review and meta-analysis
- Alcohol-induced CYP2E1, mitochondrial dynamics and retrograde signaling in human hepatic 3D organoids
- CYP2E1 gene promoter polymorphism-1293G> C increases the risk of essential hypertension in men with alcohol abuse
- Polymorphisms in NEIL-2, APE-1, CYP2E1 and mdm2 genes are independent predictors of gastric cancer Risk in a Northern Jiangsu Population (China)
- Interactions of inhibitor molecules with the human CYP2E1 enzyme active site
- Resveratrol pretreatment affects CYP2E1 activity of chlorzoxazone in healthy human volunteers
- Role of CYP2E1-mediated metabolism in the acute and vestibular toxicities of nineteen nitriles in the mouse
- Induction of CYP2E1 in testes of isoniazid-treated rats as possible cause of testicular disorders
- A case control study on relationship between lung cancer and genetic polymorphism of CYP1A1, CYP2E1 and GSTM1 in Han Nationality in Guangzhou area
- A case control study on the impact of CYP2E1 and GST-M1 polymorphisms on the risk of lung cancer
- A Case–control and a family-based association study revealing an association between CYP2E1 polymorphisms and nasopharyngeal carcinoma risk …
- A case-control study of CYP2E1 (PstI) and CYP1A1 (MspI) polymorphisms in colorectal cancer
- A Case-Control Study on Effects of Genetic Polymorphisms of GSTM1, GSTT1, CYP1A1 and CYP2E1 on Risk of Lung Cancer.
- A comparison of substrate dynamics in human CYP2E1 and CYP2A6
- A comparison of the inhibitory effects of four volatile anaesthetics on the metabolism of chlorzoxazone, a substrate for CYP2E1, in rabbits
- A decrease in S-adenosyl-L-methionine potentiates arachidonic acid cytotoxicity in primary rat hepatocytes enriched in CYP2E1
- A dietary ethanol protocol for CYP2E1 induction in CD-1 mice and its application to studies on the genotoxicity, immunotoxicity and metabolism of low-level benzene.
- A Haplotype Analysis of CYP2E1 Polymorphisms in Relation to Alcoholic Phenotypes in Mexican Americans
- A High Throughput Screening Assay to Screen for CYP2E1 Metabolism and Inhibition Using a Fluorogenic Vivid® P450 Substrate
- A Meta-analysis of CYP2E1 Genetic Polymorphism and Gastric Cancer Susceptibility [J]
- A meta-analysis on association of CYP2E1 rs2031920 and rs3813867 polymorphisms with breast cancer risk
- A multiplex-PCR/RFLP procedure for simultaneous CYP2E1, mEH and GSTM1 genotyping
- A Nanosensor System Based On Disuccinimydyl–CYP2E1 for Amperometric Detection of the Anti-Tuberculosis Drug, Pyrazinamide
- A negative cooperativity mechanism of human CYP2E1 inferred from molecular dynamics simulations and free energy calculations
- A novel lipopolysaccharide‐modulated Jun binding repressor in intron 2 of CYP2E1
- A novel polymorphism rs1329149 of CYP2E1 and a known polymorphism rs671 of ALDH2 of alcohol metabolizing enzymes are associated with colorectal cancer in a …
- A novel role of CYP2E1 in human megakaryocyte development
- A polymorphism in the 5′-flanking region of the CYP2E1 gene and elevated lung adenocarcinoma risk in a Japanese population
- A reaction network model for CYP2E1-mediated metabolism of toxicant mixtures
- A regulatory variant in CYP2E1 affects the risk of lung squamous cell carcinoma
- A relationship between genetic polymorphisms of CYP2E1 and susceptibility of acute leukemia in Gansu population
- A significantly joint effect between arsenic and occupational exposures and risk genotypes/diplotypes of CYP2E1, GSTO1 and GSTO2 on risk of urothelial carcinoma
- A single nucleotide polymorphism in the CYP2E1 gene promoter affects skatole content in backfat of boars of two commercial Duroc-sired crossbred populations
- A study for regulation of ethanol-inducible P450(CYP2E1) on CCl4-induced hepatic damage
- A study on the effects of Lauric acid on ROS formation and CYP2E1 mRNA expression in alcohol-induced HEPG2 cells
- A Study on the Optimization of CYP2E1 Enzyme Activity in C57Bl/6 Mouse Brain and Liver/C57Bl/6 Fare Beyin ve Karaciger Mikrozomlarinda CYP2E1 Enzim …
- A systematic evaluation of microRNAs in regulating human hepatic CYP2E1
- A systematically combined genotype and functional combination analysis of CYP2E1, CYP2D6, CYP2C9, CYP2C19 in different geographic areas of mainland …
- A temporal study on the histopathological, biochemical and molecular responses of CCl4-induced hepatotoxicity in CYP2E1-null mice
- A-71G> T Nucleotide Substitution uncouples IFN-[gamma]-dependent Suppression of CYP2E1 mRNA
- Abnormal liver function associated with polymorphism of GSTT1, GSTM1 and CYP2E1 in workers exposed to N, N-dimethylformamide
- Absence of acrylamide-induced genotoxicity in CYP2E1-null mice: evidence consistent with a glycidamide-mediated effect
- Acetaldehyde as a substrate for ethanol-inducible cytochrome P450 (CYP2E1)
- Acetaldehyde as well as ethanol is metabolized by human CYP2E1
- Acetaldehyde generating enzyme systems: roles of alcohol dehydrogenase, CYP2E1 and catalase, and speculations on the role of other enzymes and processes
- Acetaminophen alters microsomal ryanodine Ca2+ channel in HepG2 cells overexpressing CYP2E1
- Acetaminophen and Isoniazid treatment leads to oxidative stress and cytotoxicity in cerebellar granule neurons possibly by CYP2E1 activation
- Acetoacetate induces CYP2E1 protein and suppresses CYP2E1 mRNA in primary cultured rat hepatocytes
- Acetone catabolism by cytochrome P450 2E1: studies with CYP2E1-null mice
- Aconitine, a famous active and toxic alkaloid, has no impact on the activities of CYP1A2, CYP2D6, CYP2E1, and CYP3A in rats
- Action-mechanisms of Genetic Polymorphism in the CYP2E1 on Susceptibility to Polycyclic Aromatic Hydrocarbons
- Activation of alkylhydrazines to free radical intermediates by ethanol-inducible cytochrome P-4502E1 (CYP2E1)
- Activity of CYP2E1 and CYP3A enzymes in adults with moderate alcohol consumption: a comparison with nonalcoholics
- Activity of immobilised rat hepatic microsomal CYP2E1 using alumina membrane as a support
- Acute ethanol pretreatment increases FAS-mediated liver injury in mice: role of oxidative stress and CYP2E1-dependent and-independent pathways
- Additive effects of mitochondrion-targeted cytochrome CYP2E1 and alcohol toxicity on cytochrome c oxidase function and stability of respirosome complexes
- Adenovirus mediated overexpression of CYP2E1 increases sensitivity of HepG2 cells to acetaminophen induced cytotoxicity
- Adenovirus‐mediated expression of Cu/Zn‐or Mn‐superoxide dismutase protects against CYP2E1‐dependent toxicity
- Adenovirus-mediated expression of CYP2E1 produces liver toxicity in mice
- ADH2 and CYP2E1 genetic polymorphisms: risk factors for alcohol-related birth defects
- Administration of the tris salt of α-tocopheryl hemisuccinate inactivates CYP2E1, enhances microsomal α-tocopherol levels and protects against carbon tetrachloride …
- Advances in the interpretation and prediction of CYP2E1 metabolism from a biochemical perspective
- Adverse Birth Outcomes Associated with Maternal Smoking and Polymorphisms in the N-Nitrosamine-Metabolizing Enzyme Genes NQO1 and CYP2E1
- Age-dependent features of CYP3A, CYP2C, and CYP2E1 functioning at metabolic syndrome
- Ageing is associated with increased expression but decreased activity of CYP2E1 in male Wistar rats
- Age-related changes in the protein and mRNA levels of CYP2E1 and CYP3A isoforms as well as in their hepatic activities in Wistar rats. What role for oxidative stress?
- ALCOHOL AND CANCER SY05-1 CARCINOGENIC ETHENO DNA ADDUCTS GENERATED DURING INFLAMMATION AND CYP2E1 INDUCTION IN VARIOUS …
- Alcohol intake and folate antagonism via CYP2E1 and ALDH1: Effects on oral carcinogenesis
- Alcohol Suppresses Cardiovascular Diurnal Variations In Male Normotensive Rats: Role Of Reduced PER2 Expression And CYP2E1 Hyperactivity In The Heart
- Alcoholic liver disease: from CYP2E1 to CYP2A5
- Alcohol-Induced Increase in the Content of CYP2E1 in Human Liver Microsomes Causes a Multifold Activation of CYP3A4 and Attenuates its Cooperativity
- ALDH2 and CYP2E1 genotypes, urinary acetaldehyde excretion and the health consequences in moderate alcohol consumers
- All trans retinoic acid modulates TNF-α and CYP2E1 pathways and enhances regression of ethanol-induced fibrosis markers in hepatocytes and HSCs in abstaining …
- Allele and genotype frequencies of polymorphic cytochromes P450 (CYP2C9, CYP2C19, CYP2E1) and dihydropyrimidine dehydrogenase (DPYD) in the Egyptian …
- ALLELIC VARIANTS OF CYP2E1 GENE IN HEPATOCARCINOMA PATIENTS AND IN HEPATIC TUMOR CELL LINES
- Allylnitrile metabolism by CYP2E1 and other CYPs leads to distinct lethal and vestibulotoxic effects in the mouse
- Alteration in the expression of cytochrome P450s (CYP1A1, CYP2E1, and CYP3A11) in the liver of mouse induced by microcystin-LR
- Alterations in toxicokinetics of trichloroethylene (TCE) and trichloroacetic acid (TCA) due to cytochrome P450 2E1 (CYP2E1) induction
- Altered ethylbenzene-mediated hepatic CYP2E1 expression in growth hormone-deficient dwarf rats
- Amelioration of oxidative stress by dandelion extract through CYP2E1 suppression against acute liver injury induced by carbon tetrachloride in sprague‐dawley rats
- An estimate of polymorphism of ADH1B, ALDH2, and CYP2E1 alcohol biotransformation genes in Siberian indigenous and immigrant populations
- An improved in vitro method for screening toxin and medicine targeting CYP2E1
- An interaction between the cytochrome P450 probe substrates chlorzoxazone (CYP2E1) and midazolam (CYP3A)
- An investigation of CYP2E1 phenotype determination utilizing modeling and simulation studies
- An investigation of the induction of hepatic CYP2E1 by low doses of nicotine in the rat.
- An Rsa I Polymorphism in the CYP2E1 Gene Does Not Affect Lung Cancer Risk in a Japanese Population
- An Updated Meta-Analysis On CYP2E1 RsaI/PstI And DraI Polymorphisms And Risk Of Anti-Tuberculosis Induced Hepatotoxicity: Evidence From 26 Studies
- Analysis of CYP2E1 and GSTM1 polymorphisms for the determination of genetic susceptibility to Korean patients with colon cancer
- Analysis of CYP2E1 polymorphism for the determination of genetic susceptibility to gastric cancer in Koreans
- Analysis of CYP2E1, GSTM1 genetic polymorphisms in relation to human lung cancer and esophageal carcinoma
- Analysis of differential substrate selectivities of CYP2B6 and CYP2E1 by site-directed mutagenesis and molecular modeling
- Analysis of ethanol metabolic enzymes in primary human mammary epithelial cells and MCF‐10A cells: possible participation of CYP2E1 in ethanol‐induced oxidative …
- Analysis of human CYP2E1 mRNA in a HepG2 cell line by reverse transcription-polymerase chain reaction (RT-PCR)
- Analysis of point mutation in exon 2 of CYP2E1 gene in renal cell/urothelial cancer patients in comparison with control population.
- Analysis of protein and mRNA expressions of CYP1A1, CYP2E1, NQO1 and GST enzymes in liver, colon and prostate cancer cell lines to study drug and …
- and CYP2E1 and N‐terminal truncated CYP1A1 proteins in Saccharomyces cerevisiae − role of protein kinase A in the mitochondrial targeting of CYP2E1
- Antibiotic furazolidone induces CYP1A but not CYP2E1 subfamily in rat liver
- Antioxidant and pro-oxidant effects of a manganese porphyrin complex against CYP2E1-dependent toxicity
- Antioxidant and pro-oxidant mechanisms of (+) catechin in microsomal CYP2E1-dependent oxidative stress
- Antioxidant Peptides from Protein Hydrolysate of Microalgae Navicula incerta and their Protective Effects in Hepg2/CYP2E1 Cells Induced by Ethanol
- Antioxidant Properties of Proanthocyanidins Attenuate Carbon Tetrachloride (CCl4)–Induced Steatosis and Liver Injury in Rats via CYP2E1 Regulation
- Apigenin protects against alcohol-induced liver injury in mice by regulating hepatic CYP2E1-mediated oxidative stress and PPARα-mediated lipogenic gene …
- APOE and CYP2E1 polymorphisms, alcohol consumption, and Parkinson’s disease in a Japanese population
- Application of a map Bayesian method for CYP2E1 phenotyping
- Application of an updated physiologically based pharmacokinetic model for chloroform to evaluate CYP2E1-mediated renal toxicity in rats and mice
- Area Under the Plasma Concentration–Time Curve of Inorganic Fluoride Following Sevoflurane Anesthesia Correlates with CYP2E1 mRNA Level in …
- Aspartame administration and insulin treatment altered brain levels of CYP2E1 and CYP3A2 in streptozotocin-induced diabetic rats
- Assessing Specificity of Indazole Derivatives as Inhibitors to CYP2E1
- Assessment of frequencies of lifestyle factors and polymorphisms of drug-metabolizing enzymes (NAT2, CYP2E1) in human hepatocellular carcinoma (HCC) patients …
- Association analysis of alcohol metabolizing enzymes ADH1B, ADH7, CYP2E1 gene polymorphism with risk for coronary atherosclerosis
- Association analysis of SNPs in the porcine CYP2E1 gene with skatole, indole, and androstenone levels in backfat of a crossbred pig population
- Association between CYP2E1 and GOT2 gene polymorphisms and susceptibility and low-dose N,N-dimethylformamide occupational exposure-induced liver injury
- Association between CYP2E1 genetic polymorphisms and lung cancer risk: a meta-analysis
- Association between CYP2E1 genetic polymorphisms and urinary cancer risk: a meta-analysis
- Association between CYP2E1 polymorphisms and risk of differentiated thyroid carcinoma
- Association between CYP2E1 polymorphisms and risk of gastric cancer: An updated meta‑analysis of 32 case‑control studies
- Association between CYP2E1 polymorphisms and susceptibility to prostate cancer
- Association between genetic polymorphism of GSTM1, CYP2E1 and susceptibility to cervical cancer and its precancerous lesions in Uighur women in Xinjiang
- Association between genetic polymorphisms of CYP2E1 and lung cancer susceptibility: a case control study
- Association between genetic variants in CYP2E1 and CTRC genes and susceptibility to alcoholic pancreatitis: A systematic review and meta-analysis
- Association between polymorphism of GSTP1, GSTT1, GSTM1 and CYP2E1 genes and susceptibility to benzene-induced hematotoxicity
- Association between polymorphisms in the CYP1A1, CYP2E1 and GSTM1 genes, and smoking, alcohol and upper digestive tract carcinomas in a high …
- Association between the CYP2E1 polymorphisms and lung cancer risk: a meta-analysis
- Association between the TP53 and CYP2E1* 5B gene polymorphisms and non-small cell lung cancer
- CYP2E1_gene_polymorphism.13.aspx”>Association of combined CYP2E1 gene polymorphism with the risk for esophageal squamous cell carcinoma in Huai’an population, China
- CYP2E1_gene_polymorphisms_with_prostate_cancer_in_a_Lebanese_population/links/5635d13b08aebc003fff7840.pdf”>Association of CYP1A1 and CYP2E1 gene polymorphisms with prostate cancer in a Lebanese population
- Association of CYP2E1 and CYP1A1m2 (BsrD1) polymorphisms with cytogenetic biomarkers in petrol pump workers
- Association of CYP2E1 and NAT2 gene polymorphisms with chronic obstructive pulmonary disease
- Association of CYP2E1 gene polymorphism with predisposition to cancer development
- Association of CYP2E1 gene polymorphisms with bladder cancer risk: A systematic review and meta-analysis
- Association of CYP2E1 of PON2311 polymorphisms in neonates with preterm
- Association of CYP2E1, GST and mEH genetic polymorphisms with urinary acrylamide metabolites in workers exposed to acrylamide
- Association of CYP2E1, NQO1 and GST genetic polymorphisms with risk of acute lymphoblastic leukemia in turkish children
- Association of genetic polymorphisms in CYP2E1, MPO, NQO1, GSTM1, and GSTT1 genes with benzene poisoning.
- Association of genetic polymorphisms of CYP2E1, NAT2, GST and SLCO1B1 with the risk of anti-tuberculosis drug-induced liver injury: a systematic review and meta …
- Association of GSTM1, CYP1A1 and CYP2E1 genetic polymorphisms with susceptibility to lung adenocarcinoma: A case‐control study in Chinese population
- Association of GSTM1, GSTT1 and CYP2E1 gene polymorphisms with antituberculosis drug induced hepatotoxicity in North Indian population
- Association of GSTM1, GSTT1, GSTP1 and CYP2E1 single nucleotide polymorphisms with colorectal cancer in Iran
- Association of GSTM1, P1, T1 and CYP2E1 Single Nucleotide Polymorphisms with Colorectal Cancer in Iran: 391
- Association of mitochondrial deoxyribonucleic acid mutation with polymorphism in CYP2E1 gene in oral carcinogenesis
- Association of NAT2, GST and CYP2E1 polymorphisms and anti-tuberculosis drug-induced hepatotoxicity
- Association of radiation risk in the second and third generations with polymorphisms in the genes CYP1A1, CYP2E1, GSTP1 and changes in the thyroid
- Association of the blood biochemical index with CYP2E1 5’flanking region Rsa I/Pst I gene polymorphism and alcohol consumption habit in Southern Taiwan …
- Association of the CYP2E1, FMO3, NQO1, GST, NOS3 genetic polymorphisms with ischemic stroke risk in Turkish population
- Association Studies of Polymorphisms of CYP2E1 Gene in Alcoholics with Cirrhosis, Antisocial Personality, and Normal Controls
- Associations between CYP1A1 and CYP2E1 polymorphisms and susceptibility to esophageal cancer in Chaoshan and Taihang areas of China
- Associations between CYP2E1 promoter polymorphisms and plasma 1, 3-dimethyluric acid/theophylline ratio
- Associations between CYP2E1 promoter polymorphisms and plasma 1, 3-dimethyluric acid/theophylline ratios
- Associations of CYP1A1, GSTM1, and CYP2E1 polymorphisms with lung cancer suggest cell type specificities to tobacco carcinogens
- Associations of CYP2E1 rs2031920 and rs3813867 polymorphisms with colorectal cancer risk: a systemic review and meta-analysis
- Associations of Rsa I polymorphism at the 5’flanking region of CYP2E1 and PON2 148 polymorphism in neonates with preterm delivery
- Author Correction: Effect of BI-1 on insulin resistance through regulation of CYP2E1
- Author’s Reply to Reith:“Morbidly Obese Patients Exhibit Increased CYP2E1-Mediated Oxidation of Acetaminophen”
- Autophagy protects against CYP2E1/chronic ethanol-induced hepatotoxicity
- B107 TUBERCULOSIS: ISSUES DURING TREATMENT: An Updated Meta-Analysis On CYP2E1 Rsai/psti And Drai Polymorphisms And Risk Of Anti-Tuberculosis …
- Baicalin ameliorates liver injury induced by chronic plus binge ethanol feeding by modulating oxidative stress and inflammation via CYP2E1 and NRF2 in …
- Benzene-induced genotoxicity in mice in vivo detected by the alkaline comet assay: reduction by CYP2E1 inhibition
- bias and subsequent nonalcoholic steatohepatitis progression is attenuated by nitric oxide donor DETA NONOate via inhibition of CYP2E1-induced oxidative stress in …
- Bimodal targeting of microsomal CYP2E1 to mitochondria through activation of an N-terminal chimeric signal by cAMP-mediated phosphorylation
- Binge alcohol promotes acute liver injury through a CYP2E1‐HIF‐1α‐dependent apoptosis pathway in mice and humans (1010.1)
- Binge alcohol promotes hypoxic liver injury through a CYP2E1–HIF-1α-dependent apoptosis pathway in mice and humans
- Bioactivation of 1, 1-dichloroethylene by CYP2E1 and CYP2F2 in murine lung
- Bioactivation of 1, 1-dichloroethylene to its epoxide by CYP2E1 and CYP2F enzymes
- Bioinformatic Analysis of the Main Characteristics and Structure of the Gene Encoding CYP2E1 Protein.
- Bioinformatics of CYP2E1 CpG intron methylation sites and application to HAR1-RELN sequence analysis
- Biotransformation of caffeine, paraxanthine, theobromine and theophylline by cDNA-expressed human CYP1A2 and CYP2E1.
- Bortezomib alleviates drug-induced liver injury by regulating CYP2E1 gene transcription
- Brain CYP2E1 is induced by nicotine and ethanol in rat and is higher in smokers and alcoholics
- Breaking self-tolerance toward cytochrome P4502E1 (CYP2E1) in chronic hepatitis C: possible role for molecular mimicry
- Butadiene-induced mitochondrial dysfunction is correlated with mitochondrial CYP2E1 activity in Collaborative Cross mice
- by allyl sulfides and phenethyl isothiocyanate of methyl-n-pentylnitrosamine depentylation by rat esophageal microsomes, human and rat CYP2E1, and Rat CYP2A3
- Ca2+-dependent and independent mitochondrial damage in HepG2 cells that overexpress CYP2E1
- Camelus dromedarius Putative Cytochrome P450 Enzyme CYP2E1: Complete Coding Sequence and Phylogenetic Tree
- Caralluma umbellata Haw. protects liver against paracetamol toxicity and inhibits CYP2E1
- CARBON MONOXIDE PROTECTS MICROSOMES FROM ETHANOL-DERIVED OXIDATIVE STRESS MEDIATED BY CYP2E1
- Case Control Study of Genetic Polymorphism of Cytochrome P4502E1 5′(CYP2E1 5′) and Susceptibility of Occupational Manganism [J]
- Case-control study of the polymorphisms of CYP2E1-RsaⅠ and GSTT1 genes and susceptibility to pancreatic cancer
- CCl 4-induced hepatotoxicity: protective effect of rutin on p53, CYP2E1 and the antioxidative status in rat
- cDNA sequence, deduced amino acid sequence, predicted gene structure and chemical regulation of mouse CYP2E1
- Cervical cancer and CYP2E1 polymorphisms: implications for molecular epidemiology
- Changes in coumarin kinetics and subcellular localization of CYP2E1 contribute to bile duct damage and reduce hepatocellular damage after repeated administration …
- Changes of CYP2E1 activity in diabetic rat model
- Characterization of a dietary ethanol protocol for CYP2E1 induction in the CD-1 mouse without evident hepatic toxicity or genotoxicity
- Characterization of cytochrome P4502E1 turnover in transfected HepG2 cells expressing human CYP2E1
- Characterization of polymorphisms of genes ADH2, ADH3, ALDH2 and CYP2E1 and relationship to the alcoholism in a Colombian population
- Chemical characteristics for optimizing CYP2E1 inhibition
- CHIP−/−-Mouse Liver: Adiponectin-AMPK-FOXO-Activation Overrides CYP2E1-Elicited JNK1-Activation, Delaying Onset of NASH: Therapeutic Implications
- Chlormethiazole, an inhibitor of CYP2E1, prevented chemical carcinogen-initiated and alcohol-promoted hepatic carcinongenesis in rats.
- CYP2E1_Activity_in_Humans/links/54b536b40cf26833efd080d9.pdf”>Chlorzoxazone as a Single Sample Probe of Hepatic CYP2E1 Activity
- Chlorzoxazone as a single sample probe of hepatic CYP2E1 activity in humans
- Chlorzoxazone is metabolized by human CYP1A2 as well as by human CYP2E1
- Chlorzoxazone metabolism by winter flounder liver microsomes: evidence for existence of a CYP2E1-like isoform in teleosts
- Chlorzoxazone, a selective probe for phenotyping CYP2E1 in humans
- Chlorzoxazone: An in vitro and in vivo substrate probe for liver CYP2E1
- Chronic administration of caderofloxacin, a new fluoroquinolone, increases hepatic CYP2E1 expression and activity in rats
- Chronic alcohol intake-induced oxidative stress and apoptosis: role of CYP2E1 and calpain-1 in alcoholic cardiomyopathy
- Chronic ethanol and high glucose inducible CYP2E1 mediated oxidative stress leads to greater cellular injury in VL-17A cells: a potential mechanism for liver injury …
- Chronic ethanol feeding potentiates Fas Jo2-induced hepatotoxicity: Role of CYP2E1 and TNF-α and activation of JNK and P38 MAP kinase
- Cloning and bioinformatics revealed molecular characterisation of CYP2E1 gene from bactrian camel (Camelus bactrianus)
- Cloning and expression of rat CYP2E1 in Saccharomyces cerevisiae: Detection of genotoxicity of N‐alkylformamides
- Cloning and sequence analysis of human embryonic nasopharyngeal epithelial CYP2E1 cDNA
- Combined analysis of germline polymorphisms of p53, GSTM1, GSTT1, CYP1A1, and CYP2E1: relation to the incidence rate of cervical carcinoma
- Combined metadoxine and garlic oil treatment efficaciously abrogates alcoholic steatosis and CYP2E1 induction in rat liver with restoration of AMPK activity
- Comment on:“Morbidly Obese Patients Exhibit Increased CYP2E1-Mediated Oxidation of Acetaminophen”
- Comparative analysis of binding affinities between styrene and mammalian CYP2E1 by bioinformatics approaches
- Comparative metabolism and disposition of trichloroethylene in CYP2E1–/–and wild-type mice
- Comparing the protective effects of three sulfur compounds against acrylonitrile-induced acute toxicity in CYP2E1-induced rats
- Comparison of chlorzoxazone one-sample methods to estimate CYP2E1 activity in humans
- Comparison of cytochrome P4502E1 (CYP2E1) activity and hepatic and lymphocyte mRNA expression in patients with chronic hepatitis C
- Comparison of genetic polymorphisms of CYP2E1, ADH2, and ALDH2 genes involved in alcohol metabolism in Koreans and four other ethnic groups
- Comparison of germ cell mutagenicity in male CYP2E1-null and wild-type mice treated with acrylamide: evidence supporting a glycidamide-mediated effect
- Comparison of levels of cytochromes P‐450, CYP1A2, CYP2E1, and their related monooxygenase activities in human surgical liver samples
- COMPARISON OF POLYMORPHISM rs2070672 CYP2E1 GENE PROPORTION IN EARLY AND ADVANCED STAGE OF UNDIFFERENTIATED TYPE …
- CYP2E1-gene-in-various-clinical-stage-of-undifferentiated-type-nasopharyngeal-carcinoma/”>Comparison of Polymorphism rs3813865 Cytochrome P450 Family 2 Subfamily E Polypeptide 1 (CYP2E1) Gene in Various Clinical Stage of Undifferentiated …
- Comparison of the polymorphic regions of the cytochrome P450 CYP2E1 gene of humans and patas and cynomolgus monkeys
- Comparison of the susceptibility of wild-type and CYP2E1 knockout mice to the hepatotoxic and pneumotoxic effects of styrene and styrene oxide
- Compatible effects of euphorbia and glycyrrhiza on CYP2E1 expression and activity in rat liver
- Computational Docking Investigations of Oxidative Metabolism of 4-Nitroanisole with CYP2E1
- Computational Docking Simulations of Nitroanisole and Nitrophenol with CYP2E1
- Computational docking studies of nitroanisoles and nitrophenols with CYP2E1
- Concentration-dependent inhibitory effect of Baicalin on the plasma protein binding and metabolism of chlorzoxazone, a CYP2E1 probe substrate, in rats in …
- Conformational anti‐cytochrome P4502E1 (CYP2E1) auto‐antibodies contribute to necro‐inflammatory injury in chronic hepatitis C
- Constitutive and inducible expression of hepatic CYP2E1 in leptin-deficient ob/ob mice
- Construction and assessment of models of CYP2E1: predictions of metabolism from docking, molecular dynamics, and density functional theoretical calculations
- Construction and Identification of miRNA Expression Vector Targeting on Mouse CYP2E1
- Construction of a CYP2E1-template system for prediction of the metabolism on both site and preference order
- Construction of CRISPR/Cas9-mediated genomic deletion of the CYP2E1 gene in human HEK293FT cell line
- Construction of CYP2E1 recombinant adenovirus vector and its anti-tumor effects
- Contributing Roles of CYP2E1 and Other Cytochrome P450 Isoforms in Alcohol-Related Tissue Injury and Carcinogenesis
- Contribution of CYP2E1 and CYP3A to acetaminophen reactive metabolite formation
- Contribution of CYP2E1 polymorphism to aging in the mechanical workshop workers
- Contribution of CYP2E1 to N-methyl-2-pyrrolidone metabolism
- Contribution of the ALDH2 and CYP2E1 genes to flushing response and drinking patterns in Japanese healthy volunteers
- Contributions of caspase-8 and-9 to liver injury from CYP2E1-produced metabolites of halogenated hydrocarbons
- CONTROL OF BOAR TAINT BY USING GENETIC MARKERS: A SINGLE NUCLEOTIDE POLYMORPHISM IN THE CYP2E1 GENE PROMOTER AFFECTS …
- Cooperativity in CYP2E1 metabolism of acetaminophen and styrene mixtures
- Correction to The Action of Cytochrome b5 on CYP2E1 and CYP2C19 Activities Requires Anionic Residues D58 and D65
- Correction to: CYP2E1-mediated oxidative stress regulates HO-1 and GST expression in maneb-and paraquat-treated rat polymorphonuclear leukocytes
- Correlation analyses of ALDH2 and CYP2E1 genetic polymorphism with personality
- Correlation between genetic polymorphism in CYP2E1, GST and toxicity of dimethylformamide
- CORRELATION BETWEEN GENETIC POLYMORPHISM OF CYP2E1 AND SUSCEPTIBILITY OF ESOPHAGEAL CANCER IN GANSU PROVINCE
- Correlation between genetic polymorphisms of CYP2E1 DraⅠ and susceptibility of gastric cancer in Qinghai province
- Correlation between genetic polymorphisms of CYP2E1 DraⅠ and susceptibility of gastric cancer in Qinghai province [J]
- CORRELATION BETWEEN GENETIC POLYMORPHISMS OF CYP2E1 RSAⅠ AND SUSCEPTIBILITY OF GASTRIC CANCER IN QINGHAI PROVINCE [J]
- Correlation between spermatogenesis disorders and rat testes CYP2E1 mRNA contents under experimental alcoholism or type I diabetes
- Covalent immobilization of recombinant human cytochrome CYP2E1 and glucose-6-phosphate dehydrogenase in alumina membrane for drug screening applications
- Covalent modification and time-dependent inhibition of human CYP2E1 by the meta-isomer of acetaminophen
- Critical role of cytochrome P450 2E1 (CYP2E1) in the development of high fat-induced non-alcoholic steatohepatitis
- Crosstalk between CYP2E1 and CYP3A enzymes and its Possible Involvement in Alcohol‐Drug Interactions.
- Cryopreserved porcine hepatocytes: expression and induction of cytochrome P450, isoform CYP2E1
- Cutaneous CYP2E1 induction after topical treatment by dexamethasone, ethanol and salicylic acid in mouse.
- Cyclosporine A protects against arachidonic acid toxicity in rat hepatocytes: role of CYP2E1 and mitochondria
- CYP17A1 and CYP2E1 variants associated with high altitude polycythemia in Tibetans at the Qinghai-Tibetan Plateau
- CYP1A1 and CYP2E1 genotypes and risk of esophageal squamous cell carcinoma in a high-incidence region, Kashmir
- CYP1A1 and CYP2E1 polymorphism frequencies in a large Brazilian population
- CYP1A1 CYP2E1 and GSTM1 polymorphisms are not associated with susceptibility to squamous‐cell carcinoma of the esophagus
- CYP1A1, CYP2D6, CYP2E1, NAT2, GSTM1 and GSTT1 polymorphisms or their combinations are associated with the increased risk of the laryngeal squamous cell …
- CYP1A1, CYP2E1 and EPHX1 polymorphisms in sporadic colorectal neoplasms
- CYP1A1, CYP2E1 and gastric cancer risk in a high-incidence Colombian population
- CYP1A1, CYP2E1 and GSTM1 genetic polymorphisms. The effect of single and combined genotypes on lung cancer susceptibility in Chilean people
- CYP1A1, CYP2E1, and GSTM1 gene polymorphisms and susceptibility to colorectal and gastric cancer among Lebanese
- CYP1A1, CYP2E1, GSTM1, GSTT1, EPHX1 exons 3 and 4, and NAT2 polymorphisms, smoking, consumption of alcohol and fruit and vegetables and risk of head …
- CYP1A1, CYP2E1, GSTM1, GSTT1, GSTP1, and TP53 polymorphisms: do they indicate susceptibility to chronic obstructive pulmonary disease and non-small-cell …
- CYP1A2* 1C, CYP2E1* 5B, and GSTM1 polymorphisms are predictors of risk and poor outcome in head and neck squamous cell carcinoma patients
- CYP1AI and CYP2E1 gene polymorphisms may increase susceptibility to Oral Submucous Fibrosis among betel quid chewers of Eastern India
- CYP2A6 and CYP2E1 polymorphisms in a Brazilian population living in Rio de Janeiro
- CYP2A6/2A7 and CYP2E1 expression in human oesophageal mucosa: regional and inter-individual variation in expression and relevance to nitrosamine metabolism
- CYP2E1
- CYP2E1 active site residues in substrate recognition sequence 5 identified by photoaffinity labeling and homology modeling
- CYP2E1 activity and children with obesity: possible confounding factors
- CYP2E1 activity before and after weight loss in morbidly obese subjects with nonalcoholic fatty liver disease
- CYP2E1 activity in cisplatin resistant cancer cells
- CYP2E1 activity in patients with alcoholic liver disease
- CYP2E1 activity on ARPE-19 cells: New approach to RPE ethanol metabolism
- CYP2E1 and ALDH2 Gene Polymorphisms in Squamous Cell Head and Neck
- CYP2E1 and ALDH2 gene polymorphisms in squamous cell head and neck cancer in the Turkish population
- CYP2E1 and ALDH2 genotypes and alcohol dependence in Japanese
- CYP2E1_and_catalase_influence_ethanol_sensitivity.7.aspx”>CYP2E1 and catalase influence ethanol sensitivity in the central nervous system
- CYP2E1 and clinical features in alcoholics
- CYP2E1 and CYP3A1/2 gene expression is not associated with the ursodeoxycholate effect on ethanol-induced lipoperoxidation
- CYP2E1 and CYP4A as microsomal catalysts of lipid peroxides in murine nonalcoholic steatohepatitis
- CYP2E1 and GSTM1 gene polymorphisms, environmental factors, and the susceptibility to lung cancer
- CYP2E1 and miRNA‐378a‐3p contribute to acetaminophen‐or tripterygium glycosides‐induced hepatotoxicity
- CYP2E1 and NQO1 genotypes and bladder cancer risk in a Lebanese population
- CYP2E1_and_nqo1_genotypes,_smoking_and_bladder.6.aspx”>CYP2E1 and NQO1 genotypes, smoking and bladder cancer
- CYP2E1 and oxidant stress in alcoholic and non-alcoholic fatty liver disease
- CYP2E1 and oxidative liver injury by alcohol
- CYP2E1 and Parkinson’s disease in a MPTP-induced C57BL/6 mouse model
- CYP2E1 and risk of chemically mediated cancers
- CYP2E1_and_XRCC1_Genetic_Polymorphisms_and_the.906.aspx”>CYP2E1 and XRCC1 Genetic Polymorphisms and the Risk of Liver Fibrosis in Workers Exposed to Vinyl Chloride Monomer
- CYP2E1 autoantibodies in liver diseases
- CYP2E1 changes the biological function of gastric cancer cells via the PI3K/Akt/mTOR signaling pathway
- CYP2E1 competes with CYP2B4 for limited NADPH‐Cytochrome P450 Reductase
- CYP2E1 degradation by in vitro reconstituted systems: role of the molecular chaperone hsp90
- CYP2E1 enhances ethanol-induced lipid accumulation but impairs autophaghy in HepG2 E47 cells
- CYP2E1 epigenetic regulation in chronic, low-level toluene exposure: Relationship with oxidative stress and smoking habit
- CYP2E1 expression in bone marrow and its intra-and interspecies variability: approaches for a more reliable extrapolation from one species to another in the risk …
- CYP2E1 expression in human lymphocytes from various ethnic populations
- CYP2E1 Expression in Liver of Type 2 Diabetic Rats [J]
- CYP2E1 G1532C, NQO1 Pro187Ser, and CYP1B1 Val432Leu polymorphisms are not associated with risk of squamous cell carcinoma of the head and neck
- CYP2E1 gene polymorphism and ovarian cancer risk in the Yakut population
- CYP2E1 GENE POLYMORPHISM AND SUSCEPTIBILITY OF HEPATOCELLULAR CARCINOMA IN QINGHAI TIBETAN POPULATION
- CYP2E1 gene polymorphisms related to the formation of coronary artery lesions in Kawasaki disease
- CYP2E1 Gene Promoter Polymorphism -1293G>C Increases the Risk of Essential Hypertension in Men with Alcohol Abuse
- CYP2E1 gene rs6413420 polymorphism was first found in the Bouyei ethnic group of China
- CYP2E1 Genetic Polymorphism relating to Styrene Metabolism of Korean Workers
- CYP2E1 genetic polymorphisms and risk of nasopharyngeal carcinoma in Taiwan
- CYP2E1 genotype and isoniazid-induced hepatotoxicity in patients treated for latent tuberculosis
- CYP2E1 genotype and transaminase level of tuberculosis patients receiving fixed dose combination of antituberculosis
- CYP2E1 genotypes and serum LAP in Japanese alcoholics
- CYP2E1 genotyping in renal cell/urothelial cancer patients in comparison with control populations.
- CYP2E1 hydroxylation of aniline involves negative cooperativity
- CYP2E1 immunoglobulin G4 subclass antibodies after desflurane anesthesia
- CYP2E1 impairs GLUT4 gene expression and function: NRF2 as a possible mediator
- CYP2E1 in the human retinal pigment epithelium: expression, activity, and induction by ethanol
- CYP2E1 induced by ethanol causes oxidative stress, proteasome inhibition and cytokeratin aggresome (Mallory body-like) formation
- CYP2E1 induction leads to oxidative stress and cytotoxicity in glutathione-depleted cerebellar granule neurons
- CYP2E1 inhibition enhances mallory body formation
- CYP2E1 is a central mediator for the synergistic effects of alcohol and free fatty acids on hepatocellular steatosis and inflammation
- CYP2E1 is not involved in early alcohol-induced liver injury
- CYP2E1 is preferentially expressed in Clara cells of murine lung: localization by in situ hybridization and immunohistochemical methods.
- CYP2E1 level in peripheral lymphocytes correlates with early pathogenesis of diabetic nephropathy.
- CYP2E1 level in rat liver injured by the interaction between carbon tetrachloride and chloroform
- CYP2E1 mediated ethanol metabolism in ARPE-19 cells.
- CYP2E1 mediated isoniazid-induced hepatotoxicity in rats
- CYP2E1 Mediates Ethanol-Induced DNA Damage And TNF Release In Bronchial Epithelial Cells
- CYP2E1 metabolism of styrene involves allostery
- CYP2E1 mRNA expression, genetic polymorphisms in peripheral blood lymphocytes and liver abnormalities in Chinese VCM-exposed workers
- CYP2E1 mutation associated with increased chlorzoxazone (CZ) metabolic ability
- CYP2E1 overexpression alters hepatocyte death from menadione and fatty acids by activation of ERK1/2 signaling
- CYP2E1 overexpression in HepG2 cells induces glutathione synthesis by transcriptional activation of γ-glutamylcysteine synthetase
- CYP2E1 overexpression inhibits microsomal Ca2+-ATPase activity in HepG2 cells
- CYP2E1 overexpression up-regulates both non-specific ô-aminolevulinate synthase and heme oxygenase-1 in the human hepatoma cell line HLE/2E1
- CYP2E1 overexpression up-regulates both non-specific δ-aminolevulinate synthase and heme oxygenase-1 in the human hepatoma cell line HLE/2E1
- CYP2E1 phenotype in Mexican workers occupationally exposed to low levels of toluene
- CYP2E1 polymorphism, acetylator profiles and drug-induced liver injury incidence of Indonesian tuberculosis patients
- CYP2E1 polymorphism, cigarette smoking, p53 expression, and survival in non-small cell lung cancer: a long term follow-up study
- CYP2E1 polymorphisms and colorectal cancer risk: a HuGE systematic review and meta-analysis
- CYP2E1 polymorphisms and gene–environment interactions in the risk of upper aerodigestive tract cancers among Indians
- CYP2E1 polymorphisms and nasopharyngeal carcinoma risk: a meta-analysis
- CYP2E1 potentiates binge alcohol-induced gut leakiness, steatohepatitis, and apoptosis
- CYP2E1 potentiates toxicity in obesity and after chronic ethanol treatment
- CYP2E1 potentiation of LPS and TNFα-induced hepatotoxicity by mechanisms involving enhanced oxidative and nitrosative stress, activation of MAP kinases …
- CYP2E1 PstI polymorphism increases cervical neoplasia risk: a meta-analysis
- CYP2E1 PstI/RsaI polymorphism and colorectal cancer risk: a meta-analysis
- CYP2E1 PstI/RsaI polymorphism and interaction with alcohol consumption in hepatocellular carcinoma susceptibility: evidence from 1,661 cases and 2,317 controls
- CYP2E1 recovery is associated with a pericentral fibrosis pattern after repeated CCl4 insults
- CYP2E1 regulation by benzene and other small organic chemicals in rat liver and peripheral lymphocytes
- CYP2E1 rs2031920, COMT rs4680 polymorphisms, cigarette smoking, alcohol use and lung cancer risk in a Japanese population
- CYP2E1 Rsa I polymorphism impacts on risk of colorectal cancer association with smoking and alcohol drinking
- CYP2E1 Rsa I/Pst I polymorphism and esophageal cancer risk: a meta-analysis based on 1,088 cases and 2,238 controls
- CYP2E1 Rsa I/Pst I polymorphism contributes to oral cancer susceptibility: a meta-analysis
- CYP2E1 Rsa I/Pst I polymorphism is associated with lung cancer risk among Asians
- CYP2E1 RsaⅠpolymorphism impacts on risk of colorectal cancer association with smoking and alcohol drinking
- CYP2E1 RsaI/PstI polymorphism and gastric cancer susceptibility: meta-analyses based on 24 case-control studies
- CYP2E1 Rsai/Psti polymorphisms contributed to oral cancer susceptibility: A meta-analysis
- CYP2E1 substrate inhibition mechanistic interpretation through an effector site for monocyclic compounds
- CYP2E1 substrate inhibition. MECHANISTIC INTERPRETATION THROUGH AN EFFECTOR SITE FOR MONOCYCLIC COMPOUNDS.
- CYP2E1 substrate inhibition..
- CYP2E1 T7632A and 9-bp insertion polymorphisms and colorectal cancer risk: a meta-analysis based on 4,592 cases and 5,918 controls
- CYP2E1 VNTR genotyping associated to anti–tuberculosis drug-induced hepatotoxicity
- CYP2E1 VNTR polymorphisms and hepatocarcinoma: a gender-specific correlation
- CYP2E1* 1D regulatory polymorphism: association with alcohol and nicotine dependence
- CYP2E1* 5B, CYP2E1* 6, CYP2E1* 7B, CYP2E1* 2, and CYP2E1* 3 allele frequencies in Iranian populations
- CYP2E1, GSTM1 and GSTT1 genetic polymorphisms and susceptibility to antituberculosis drug‐induced hepatotoxicity: a nested case–control study
- CYP2E1, oxidative stress and MAPK signaling pathways in alcohol-induced hepatotoxicity
- CYP2E1, oxidative stress, post-translational modifications and lipid metabolism
- CYP2E1: biochemistry, toxicology, regulation and function in ethanol-induced liver injury
- CYP2E1: from ash to nash
- CYP2E1: Mechanism of induction by isoniazid and role in acetaminophen oxidation.
- CYP2E1: the anesthesia enzyme
- CYP2E1-and TNFalpha/LPS-induced oxidative stress and MAPK signaling pathways in alcoholic liver disease
- CYP2E1–Biochemical and Toxicological Aspects and Role in Alcohol-Induced Liver Injury
- CYP2E1-catalyzed alcohol metabolism: Role of oxidant generation in interferon signaling, antigen presentation and autophagy
- CYP2E1-catalyzed oxidation contributes to the sperm toxicity of 1-bromopropane in mice
- CYP2E1-dependent and leptin-mediated hepatic CD57 expression on CD8+ T cells aid progression of environment-linked nonalcoholic steatohepatitis
- CYP2E1-dependent benzene toxicity: the role of extrahepatic benzene metabolism
- CYP2E1-dependent bioactivation of 1, 1-dichloroethylene in murine lung: formation of reactive intermediates and glutathione conjugates
- CYP2E1-dependent bioactivation of 1, 1-dichloroethylene to reactive intermediates in murine and human lung and liver microsomes.
- CYP2E1-DEPENDENT BIOACTIVATION OF 191
- CYP2E1-dependent elevation of serum cholesterol, triglycerides, and hepatic bile acids by isoniazid
- CYP2E1-dependent hepatotoxicity and oxidative damage after ethanol administration in human primary hepatocytes
- CYP2E1-dependent oxidative stress and toxicity: role in ethanol-induced liver injury
- CYP2E1-dependent toxicity and oxidative stress in HepG2 cells
- CYP2E1-dependent toxicity and up-regulation of antioxidant genes
- CYP2E1-mediated mechanism of anti-genotoxicity of the broccoli constituent sulforaphane
- CYP2E1-mediated modulation of valproic acid-induced hepatocytotoxicity
- CYP2E1‐mediated oxidative stress induces collagen type I expression in rat hepatic stellate cells
- CYP2E1-mediated oxidative stress regulates HO-1 and GST expression in maneb-and paraquat-treated rat polymorphonuclear leukocytes
- Cytochemical Localization of the Acetone-lnducible Cytochrome P-450 Isoform, CYP2E1 in Murine Colonic Epithelium
- Cytochrome b5 coexpression increases the CYP2E1-dependent mutagenicity of dialkylnitrosamines in methyltransferase-deficient strains of Salmonella typhimurium
- Cytochrome b5 reductase and cytochrome b5 support the CYP2E1-mediated activation of nitrosamines in a recombinant Ames test
- Cytochrome CYP2E1 is critical for joint effects of alcohol and lipids on hepatocellular steatosis and inflammation
- Cytochrome CYP2E1 phenotyping and genotyping in the evaluation of health risks from exposure to polluted environments
- Cytochrome P450 2E1 (CYP2E1) is essential for acrylonitrile metabolism to cyanide: comparative studies using CYP2E1-null and wild-type mice
- Cytochrome P450 2E1 (CYP2E1) is the principal enzyme responsible for urethane metabolism: comparative studies using CYP2E1-null and wild-type mice
- Cytochrome P450 2E1 (CYP2E1) regulates the response to oxidative stress and migration of breast cancer cells
- Cytochrome P450 2E1 (CYP2E1)-dependent production of a 37-kDa acetaldehyde–protein adduct in the rat liver
- Cytochrome P-450 CYP2E1 knockout mice are protected against high-fat diet-induced obesity and insulin resistance
- Cytochrome P450 CYP2E1, but not nicotinamide adenine dinucleotide phosphate oxidase, is required for ethanol‐induced oxidative DNA damage in rodent liver
- Cytochrome P450 Genes (CYP2E1 and CYP1A1) Variants and Susceptibility to Chronic Hepatitis B Virus Infection
- Cytochrome P450 Reductase-null Mice as an Animal Model to Study Electron Transfer Pathways in Cholesterol Synthesis and CYP2E1-mediated Drug Metabolism
- Cytochrome P4502E1 (CYP2E1) expression in peripheral blood lymphocytes: evaluation in hepatitis C and diabetes
- Cytochrome P4502E1 (CYP2E1) genetic polymorphism in a case-control study of gastric cancer and liver disease.
- Cytochrome P450IIE1 (CYP2E1) is induced by skatole and this induction is blocked by androstenone in isolated pig hepatocytes
- Cytochrome p-450-mediated differential oxidative modification of proteins: albumin, apolipoprotein E, and CYP2E1 as targets
- D2-receptor-linked signaling pathways regulate the expression of hepatic CYP2E1
- Decreased CYP2E1 mRNA expression in human leucocytes in patients with fibrotic and inflammatory lung diseases
- Decreased protein and mRNA expression of ER stress proteins GRP78 and GRP94 in HepG2 cells over-expressing CYP2E1
- dehydrogenase 2, cytochrome p450 2E1 for liver cancer risk in HCV antibody-positive japanese patients and the variations of CYP2E1 mRNA expression levels in the …
- Depletion of cytosolic or mitochondrial thioredoxin increases CYP2E1-induced oxidative stress via an ASK-1–JNK1 pathway in HepG2 cells
- Depression of glutathione content, elevation of CYP2E1-dependent activation, and the principal determinant of the fasting-mediated enhancement of 1, 3-dichloro-2 …
- Detection and characterization of novel polymorphisms in the CYP2E1 gene.
- Detection of autoantibodies against cytochrome P450 2E1 (CYP2E1) in patients with recurrent hepatitis C
- Detection of auto-antibodies against cytochrome P4502E1 (CYP2E1) in chronic hepatitis C
- Detection of CYP2E1, a genetic biomarker of susceptibility to benzene metabolism toxicity in immortal human lymphocytes derived from the Han Chinese population
- Determination of the activity of human hepatic cytochromes P450 CYP2C8/9, CYP2E1
- Development and properties of HepG2 cells that constitutively express CYP2E1
- Development of a non-high pressure liquid chromatography assay to determine [14C] chlorzoxazone 6-hydroxylase (CYP2E1) activity in human liver microsomes
- Development of an IgY antibody-based immunoassay for the screening of the CYP2E1 inhibitor/enhancer from herbal medicines
- Developmental Expression of CYP2E1 in the Human Liver: Hypermethylation Control of Gene Expression During the Neonatal Period
- Diallyl sulfide inhibition of CYP2E1 does not rescue diabetic rats from thioacetamide-induced mortality
- Diallylsulfide and allylmethylsulfide are uniquely effective among organosulfur compounds in inhibiting CYP2E1 protein in animal models
- Dichloroacetic acid treatment increases hepatic CYP2E1 in male and female rats
- Dietary aflatoxin B1 intake, genetic polymorphisms of CYP1A2, CYP2E1, EPHX1, GSTM1, and GSTT1, and gastric cancer risk in Korean
- Dietary lipids affect human ethanol-inducible CYP2E1 gene expression in vivo in mononuclear cells
- Dietary omega-3 polyunsaturated fatty acids alter fatty acid composition of lipids and CYP2E1 expression in rat liver tissue
- Differences in butadiene adduct formation between rats and mice not due to selective inhibition of CYP2E1 by butadiene metabolites
- Different CYP2E1 genotypes and alcoholic liver disease.
- Different regulation and expression of the human CYP2E1 gene due to the Rsal polymorphism in the 5′-flanking region
- Differential effects of CYP2E1 status on the metabolic activation of the colon carcinogens azoxymethane and methylazoxymethanol
- Differential effects of diabetes on CYP2E1 and CYP2B4 proteins and associated drug metabolizing enzyme activities in rabbit liver
- Differential effects of dietary fatty acids on the regulation of CYP2E1 and protein kinase C in human hepatoma HepG2 cells
- Differential expression of cytochrome P4502E1 (CYP2E1) in Morris hepatomas and livers of tumor bearing rats.
- Differential expression profile of cytochrome p450 2E1 (CYP2E1) related genes associated with carbon tetrachloride-induced hepatotoxicity
- Differential in vivo effects of α‐naphthoflavone and β‐naphthoflavone on CYP1A1 and CYP2E1 in rat liver, lung, heart, and kidney
- Differential induction of ethanol-metabolizing CYP2E1 and nicotine-metabolizing CYP2B1/2 in rat liver by chronic nicotine treatment and voluntary ethanol intake
- Differential metabolism of acrylonitrile to cyanide is responsible for the greater sensitivity of male vs female mice: role of CYP2E1 and epoxide hydrolases
- Differential Modulation of CYP2E1 Activity by cAMP-Dependent Protein Kinase upon Ser129Replacement
- Differential role of CYP2E1 binders and isoniazid on CYP2E1 protein modification in NADPH-dependent microsomal oxidative reactions: free radical scavenging …
- Differential role of CYP2E1-mediated metabolism in the lethal and vestibulotoxic effects of cis-crotononitrile in the mouse
- Diminished CYP2E1 expression and formation of 2-S-glutathionyl acetate, a glutathione conjugate derived from 1, 1-dichloroethylene epoxide, in murine lung tumors
- Direct sequencing and comprehensive screening of genetic polymorphisms on CYP2 family genes (CYP2A6, CYP2B6, CYP2C8, and CYP2E1) in five ethnic …
- Distribution and differential induction of CYP2E1 by ethanol and acetone in the mesocorticolimbic system of rat
- Distribution of ADH1B, ALDH2, CYP2E1∗ 6, and CYP2E1∗ 7B genotypes in Turkish population
- Distribution of cytochrome CYP2E1 in murine liver after ethanol and acetone administration
- DLPC attenuates alcohol-induced cytotoxicity in HepG2 cells expressing CYP2E1
- DNA damage and cytotoxicity in pancreatic β-cells expressing human CYP2E1
- DNA damage in peripheral blood lymphocytes and association with polymorphisms in the promoter region of the CYP2E1 gene in alcoholics from Central Brazil
- DNA repair XRCC1 Arg399Gln polymorphism alone, and in combination with CYP2E1 polymorphisms significantly contribute to the risk of development of childhood …
- Do Endogenous Volatile Organic Chemicals Measured in Breath Reflect and Maintain CYP2E1 Levelsin Vivo?
- Docosahexaenoic acid induces apoptosis in CYP2E1-containing HepG2 cells by activating the c-Jun N-terminal protein kinase related mitochondrial damage
- Does CYP2E1 play a major role in the aggravation of isoniazid toxicity by rifampicin in human hepatocytes?
- Does CYP2E1 RsaI/PstI polymorphism confer head and neck carcinoma susceptibility?: A meta-analysis based on 43 studies
- Downregulation of the CYP2E1 ameliorates oxidative stress and apoptosis
- Down-regulation of the expression of alcohol dehydrogenase 4 and CYP2E1 by the combination of α-endosulfan and dioxin in HepaRG human cells
- Drinking Water Chlorination By-Products and Intra-Uterine Growth Restriction: is there an effect modification of the CYP2E1 G1259C gene polymorphism?
- Duration of cytochrome P-450 2E1 (CYP2E1) inhibition and estimation of functional CYP2E1 enzyme half-life after single-dose disulfiram administration in humans
- e0048 CYP2E1 increases oxidative stress and induces apoptosis of cardio myocytes in transgenic mice
- Early Alcoholic Liver Injury: Formation of Protein Adducts with Acetaldehyde and Lipid Peroxidation Products, and Expression of CYP2E1 AND CYP3A
- Effect of {gamma}-irradiation and mitomycin C (MMC) on CYP2B1 and CYP2E1 activities in rat hepatic microsomes in vitro
- Effect of 1-aminobenzotriazole on the in vitro metabolism and single-dose pharmacokinetics of chlorzoxazone, a selective CYP2E1 substrate in Wistar rats
- effect of acidic polysaccharide from Schisandra chinensis on acute ethanol-induced liver injury through reducing CYP2E1-dependent oxidative stress
- Effect of ALDH2 and CYP2E1 Gene Polymorphisms on Drinking Behavior and Alcoholic Liver Disease in Japanese Male Workers
- Effect of ammonium pyrrolidine dithiocarbamate (PDTC) on NF-κB activation and CYP2E1 content of rats with immunological liver injury
- Effect of antifungal drugs on cytochrome P450 (CYP) 1A2, CYP2D6, and CYP2E1 activities in human liver microsomes
- Effect of BI-1 on insulin resistance through regulation of CYP2E1
- Effect of Capsosiphon fulvescens on ethanol-induced liver damage in HepG2 cells over expressing CYP2E1
- Effect of chronic disulfiram administration on the activities of CYP1A2, CYP2C19, CYP2D6, CYP2E1, and N‐acetyltransferase in healthy human subjects
- Effect of cigarette smoke on hepatic and pulmonary cytochromes P450 in mouse: evidence for CYP2E1 induction in lung
- Effect of CYP2E1 gene deletion in mice on expression of microsomal epoxide hydrolase in response to VCD exposure
- Effect of CYP2E1 genetic polymorphisms on susceptibility of aplastic anemia
- Effect of CYP2E1 induction by ethanol on the immunotoxicity and genotoxicity of extended low-level benzene exposure
- Effect of CYP2E1 polymorphism on DNA stability and lung cancer susceptibility
- Effect of CYP2E1 Ras I Genotypes on CYP2E1 Enzyme Activity and DNA Damage of Immortalized Human Lymphocytes Induced by Phenol
- Effect of different radix polygoni multiflori preparata on CYP2E1 mRNA expression in rat liver [J]
- Effect of disulfiram‐mediated CYP2E1 inhibition on the disposition of vesnarinone
- Effect of Er Chen Tang on CYP2E1 and Mitochondrial Energy Metabolism in Nonalcoholic Fatty Liver Disease
- Effect of ethanol on cytochrome P450 2E1 (CYP2E1), lipid peroxidation, and serum protein adduct formation in relation to liver pathology pathogenesis
- Effect of exposure to benzo [a] pyrene on SODs, CYP1A1/1A2-and CYP2E1 immunopositive proteins in the blood clam
- Effect of exposure to benzo [a] pyrene on SODs, CYP1A1/1A2-and CYP2E1 immunopositive proteins in the blood clam Scapharca inaequivalvis
- Effect of fasting and obesity in humans on the 6‐hydroxylation of chlorzoxazone: a putative probe of CYP2E1 activity
- Effect of flavonoids extract from apocynum venetum tea on CYP2E1 in mice.
- Effect of Ganzheng formula on CYP2E1, adiponectin and TNF-α in NAFLD rats
- Effect of Gegen Powder on CYP450 Content of Liver Microsomal and Activity of CYP2E1 in Mice Acute Alcohol-induced Liver Injury
- Effect of genetic polymorphisms of toxin metabolic enzyme CYP2E1 on metabolism of styrene
- Effect of high‐dose aspirin on CYP2E1 activity in healthy subjects measured using chlorzoxazone as a probe
- Effect of jujube on the expression of CYP2E1 and TNF-alpha in the hepatic tissue of mice with alcoholic liver disease
- Effect of Leflunomide on the content of cytochrome P450 enzyme and CYP2E1 mRNA expression of mice with acute chemical injury [J]
- Effect of methacrylonitrile on cytochrome P-450 2E1 (CYP2E1) expression in male F344 rats
- EFFECT OF NARINGIN ON THE ACTIVITY OF HUMAN LIVER MICROSOMES CYP2E1 USING PROBE DRUG METHOD
- Effect of neferine on CYP450 total enzyme and CYP3A1, CYP2D1, CYP2E1 mRNA in Rats
- Effect of oleanolic acid on CYP1A2, CYP2E1 and CYP3A4 activity in healthy subjects
- Effect of piperine on CYP2E1 enzyme activity of chlorzoxazone in healthy volunteers
- Effect of quercetin on CYP1A2, CYP2E1, CYP3A2 activities and its inhibitory mechanism studies in rat liver microsomes
- Effect of Salviae Miltiorrhizae Radix et Rhizoma and Carthami Flos before and after compatibility on activities of CYP1A2, CYP2E1, and CYP3A4 from rat liver …
- Effect of Sanchi on expression of hepatic CYP2E1 in liver tissues in rats with alcoholic liver disease [J]
- Effect of Seed Coat ofEuryale ferox Extract in Non-alcoholic Fatty Liver Disease Induced by High-fat Diet in Mice by Increasing IRs-1 and Inhibiting CYP2E1
- Effect of starvation and acetone on the enzyme systems of biotransformation and toxicity of xenobiotics–CYP2E1 substrates in rats
- Effect of status epilepticus and antiepileptic drugs on CYP2E1 brain expression
- Effect of Sulfamethoxazole, Glycyrrhiza Uralensis Fisc and Fisch Fructus Forsythiae on Cytochrome CYP2E1 in Paralichthys Olivaceus by Probe Drugs
- Effect of sulfur dioxide inhalation on CYP2B1/2 and CYP2E1 in rat liver and lung
- Effect of temperature on carp CYP2E1-like isoform activity.
- Effect of TFHL on expression of CYP2E1 in liver tissue of rats with NASH.
- Effect of the CYP2E1 genotype on vinyl chloride monomer-induced liver fibrosis among polyvinyl chloride workers
- Effect of the South African traditional meat, biltong, on cancer-associated enzymes CYP2E1 and CYP1A2
- EFFECT OF TOTAL ALKALOIDES OF ACONITUM EXCELSUM REICHB ON CYP2E1 METABOLISM ACTIVITY IN MORPHINE DEPENDENT RATS [J]
- Effect of total alkaloids of Rubus alceaefolius poiron on gene expressions of CYP2E1 and CYP3A1 in rats with acute liver injury
- Effect of water miscible organic solvents on p-nitrophenol hydroxylase (CYP2E1) activity in rat liver microsomes
- Effect of XiaozhiHugan Capsule on Pathologic Changes and CYP2E1 Gene Expression of Rats with Non-alcoholic Fatty Liver [J]
- Effect of γ-irradiation and mitomycin C (MMC) on CYP2B1 and CYP2E1 activities in rat hepatic microsomes in vitro
- Effects of acrylamide on oxidant/antioxidant parameters and CYP2E1 expression in rat pancreatic endocrine cells
- Effects of acute renal failure induced by uranyl nitrate on the pharmacokinetics of intravenous theophylline in rats: the role of CYP2E1 induction in 1, 3‐dimethyluric …
- Effects of ALDH2, CYP1A1, and CYP2E1 genetic polymorphisms and smoking and drinking habits on toluene metabolism in humans
- Effects of aqueous extract of Polygoni Multiflori Radix and its main constituents on expression of mRNA of CYP1A2, CYP2C9, and CYP2E1 in human liver L02 cells
- Effects of benzene on liver, kidney and lung cyp1a, cyp2b4, CYP2E1 and cyp3a6 mrna, protein level, and drug metabolizing enzyme activities and toxicity in diabetic …
- Effects of blueberry on ultrastructural and expression of cytochrome CYP2E1 in rats with immune hepatic fibrosis
- Effects of chlorinated aliphatic hydrocarbons on the fidelity of cell division in human CYP2E1 expressing cells
- Effects of cytochrome P450 (CYP) 2A6 gene deletion and CYP2E1 genotypes on gastric adenocarcinoma
- Effects of Danshen and Its Active Components on Rat CYP2E1 Expression and Metabolism of Model CYP2E1 Probe Substrate
- Effects of diabetes on rabbit kidney and lung CYP2E1 and CYP2B4 expression and drug metabolism and potentiation of carcinogenic activity of N …
- Effects of dietary fat composition on activities of the microsomal ethanol oxidizing system and ethanol‐inducible cytochrome P450 (CYP2E1) in the liver of rats …
- Effects of Environmental Carcinogens and Genetic Polymorphisms of CYP2E1 and NAT2 on Gastric Carcinogenesis.
- Effects of environmental factors on extrahepatic CYP2E1 gene expression in mice
- Effects of ethanol on CYP2E1 levels and related oxidative stress using a standard balanced diet
- Effects of flavonoids in Lysimachia clethroides duby on the activities of cytochrome P450 CYP2E1 and CYP3A4 in rat liver microsomes
- Effects of Ganoderma lucidum polysaccharide on CYP2E1, CYP1A2 and CYP3A activities in BCG-immune hepatic injury in rats
- Effects of Ganzhengfufang on the PPARγ and CYP2E1 in the rat with nonalcoholic fatty liver disease
- Effects of genetic polymorphisms of CYP1A1, CYP2E1, GSTM1, and GSTT1 on the urinary levels of 1-hydroxypyrene and 2-naphthol in aircraft maintenance workers
- Effects of GSTM1 and CYP2E1 Genetic Polymorphism and Drinking on DNA Damage among Workers Exposed to Phenol and Acetone
- Effects of metadoxine on the expression of CYP2E1 in liver tissue of male rats with alcoholic fat liver [J]
- Effects of mitomycin (MMC) and {gamma}-ray irradiation on cytochrome p450 content and activities of CYP2B1 and CYP2E1 in rats
- Effects of mitomycin (MMC) and γ-ray irradiation on cytochome p450 content and activities of CYP2B1and CYP2E1 in rats [J]
- Effects of mitomycin (MMC) and γ-ray irradiation on cytochrome p450 content and activities of CYP2B1 and CYP2E1 in rats
- Effects of N-acetyltransferase 2 (NAT2), CYP2E1 and Glutathione-S-transferase (GST) genotypes on the serum concentrations of isoniazid and metabolites in …
- Effects of nonyphenol exposure during pregnant and lactation period on expressions of CYP2E1 mRNA and protein of hepatic tissues in offspring rats
- Effects of occupation, lifestyle and genetic polymorphisms of CYP1A1, CYP2E1, GSTM1 and GSTT1 on urinary 1-hydroxypyrene and 2-naphthol concentrations
- Effects of Purified Glycerol from Biodiesel on Cyp1a1 and CYP2E1 Expressions in CBA/CA Mice
- Effects of rifampin on CYP2E1-dependent hepatotoxicity of isoniazid in rats
- Effects of SNPs (CYP1B1* 2 G355T, CYP1B1* 3 C4326G, and CYP2E1* 5 G-1293C), smoking, and drinking on susceptibility to laryngeal cancer among Han …
- Effects of steady-state lasofoxifene on CYP2D6-and CYP2E1-mediated metabolism
- EFFECTS OF STRUCTURALLY AND FUNCTIONALLY DIVERSE GROUP OF PHYTOCHEMICALS ON ANILINE HYDROXYLATION (CYP2E1) OF CONTROL AND …
- Effects of SU-MIAN-XIN on CYP3A1 and CYP2E1 in Rat Primary Cultured Hepatocytes
- Effects of the activities and mRNA level of CYP2E1 in mouse liver microsomal by Folium Isatidis
- Effects of the ADH3, CYP2E1, and GSTP1 genetic polymorphisms on their expressions in Caucasian lung tissue
- Effects of the plant phenolic quercetin on protein and mRNA CYP1A1, CYP2E1, NQO1 and GST enzymes in colon cancer cell line SW620
- Effects of Trichloroethylene Toxicity on Normal Human Liver Cells and Hepatocytes With CYP2E1 Gene Overexpression
- Effects of Zhenyuan Capsule on Cytochrome P450 Enzymes CYP1A2, CYP3A4 and CYP2E1
- Ekspresija CYP2E1 u testisima štakora i alkoholom prouzrokovane promjene indeksa spermatogeneze i kolagena tipa I
- Elimination rate of 6-hydroxychlorzoxazone in urine as a non-invasive evaluation of cytochrome CYP2E1 activity. Lack of relationship to smoking
- Elucidation of CYP2E1 5′ regulatory RsaI/Pstl allelic variants and their role in risk for oral cancer
- End-product inhibition of skatole-metabolising enzymes CYP1A, CYP2A19 and CYP2E1 in porcine and piscine hepatic microsomes
- Environmental exposure to benzene: evaluation of urinary S-PMA and polymorphism (CYP2E1-1293G> C and NQO1 609C> T) in Campos Elíseos residents …
- ‐en‐Y gastric bypass surgery influenced pharmacokinetics of several drugs given as a cocktail with the highest impact observed for CYP1A2, CYP2C8 and CYP2E1 …
- Ephedra water decoction and cough tablets containing ephedra and liquorice induce CYP1A2 but not CYP2E1 hepatic enzymes in rats
- Epididymal CYP2E1 plays a critical role in acrylamide-induced DNA damage in spermatozoa and paternally mediated embryonic resorptions
- Epilobium hirsutum alters xenobiotic metabolizing CYP1A1, CYP2E1, NQO1 and GPx activities, mRNA and protein levels in rats
- Epoxide formation from diallyl sulfone is associated with CYP2E1 inactivation in murine and human lungs
- Establishment and toxicological application of a cell line expressing human CYP2E1
- Establishment of a p-nitrophenol oxidation-based assay for the analysis of CYP2E1 activity in intact hepatocytes in vitro
- Establishment of model with exogenous human CYP2E1 expression and inducement of substrates
- Estrogen-related receptor γ controls hepatic CB1 receptor-mediated CYP2E1 expression and oxidative liver injury by alcohol
- Ethanol and arachidonic acid produce toxicity in hepatocytes from pyrazole-treated rats with high levels of CYP2E1
- Ethanol enhanced the genotoxicity of acrylamide in human, metabolically competent HepG2 cells by CYP2E1 induction and glutathione depletion
- CYP2E1_by_protein_stabilization_Role_of_ubiquitin_conjugation_in_the_rapid_degradation_of_CYP2E1/links/58500e2508aed95c250b7b96.pdf”>Ethanol Induces CYP2E1 by Protein Stabilization
- Ethanol induces CYP2E1 by protein stabilization role of ubiquitin conjugation in the rapid degradation of CYP2E1
- Ethanol induction of CYP2A5: permissive role for CYP2E1
- Ethanol induction of CYP2A5: role of CYP2E1-ROS-Nrf2 pathway
- CYP2E1_and_catalase_influence_ethanol_sensitivity.4.aspx”>Ethanol intake and ethanol-induced locomotion and locomotor sensitization in CYP2E1 knockout mice
- Ethanol self-administration and nicotine treatment induce brain levels of CYP2B6 and CYP2E1 in African green monkeys
- Ethanol withdrawal induced CYP2E1 degradation in vivo, blocked by proteasomal inhibitor PS-341
- Ethanol-induced oxidative DNA damage and CYP2E1 expression in liver tissue of Aldh2 knockout mice
- Ethanol-induced oxidative stress is associated with EGF receptor phosphorylation in MCF-10A cells overexpressing CYP2E1
- Ethanol‐induced oxidative stress via the CYP2E1 pathway disrupts adiponectin secretion from adipocytes
- Ethanol-induction of cytochrome P450 2A5: permissive role for CYP2E1
- Ethanol‐mediated carcinogenesis in the human esophagus implicates CYP2E1 induction and the generation of carcinogenic DNA‐lesions
- Ethanol-mediated transplacental induction of CYP2E1 in fetal rat liver
- Ethanol‐related cytotoxicity catalyzed by CYP2E1‐dependent generation of reactive oxygen intermediates in transduced HepG2 cells
- Ethnic susceptibility to lung cancer: differences in CYP2E1, CYP1A1 and GSTM1 genetic polymorphisms between French Caucasian and Chilean populations
- CYP2E1_gene__polymorphism.2.aspx”>Ethnic variation in the CYP2E1 gene: polymorphism analysis of 695 African-Americans, European-Americans and Taiwanese
- Evaluation of activity of hepatic CYP2E1 following administration of Radix et Rhizoma Rhei by probe drug in rats [J]
- Evaluation of caffeine as a test drug for CYP1A2, NAT2 and CYP2E1 phenotyping in man by in vivo versus in vitro correlations
- Evaluation of influence of Andrographis paniculata on activities of CYP1A2, CYP3A4, CYP2E1 and CYP2C19 genotypes in chickens by multiple cytochrome P450 …
- Evidence for a tissue-specific induction of cutaneous CYP2E1 by dexamethasone
- Evidence for the Existence of Two Human CYP2E1 cDNAs Using Different Polyadenylation Signals
- Evidence of association of the CYP2E1 genetic polymorphism with micronuclei frequency in human peripheral blood
- Evolution of camel CYP2E1 and its associated power of binding toxic industrial chemicals and drugs
- Exacerbation of benzene pneumotoxicity in connexin 32 knockout mice: enhanced proliferation of CYP2E1-immunoreactive alveolar epithelial cells
- Examination of a CYP2E1 repeat polymorphism in a monkey model of alcohol abuse
- Experimental study on effect of Erchen decoction and Taohongsiwu decoction on CYP2E1 activities in non-alcoholic fatty liver rats
- Experimental study on the effects of combined administration of Shuanghuanglian powder for injection and levofloxacin hydrochloride injection on CYP2E1 in mice
- exposure to styrene: modulation of cytogenetic damage and levels of urinary metabolites of styrene by polymorphisms in genes CYP2E1, EPHX1, GSTM1, GSTT1 …
- Expression and activity of CYP2E1 in circulating lymphocytes are not altered in diabetic individuals
- Expression and regulation of cytochrome P450 CYP2E1 in the minipig
- Expression of CYP2E1 by human monocyte‐derived macrophages
- Expression of CYP2E1 during human fetal development: methylation of the CYP2E1 gene in human fetal and adult liver samples
- Expression of CYP2E1 gene in liver tissue in patients with hepatic cirrhosis and obstuctive jaundice
- Expression of CYP2E1 gene in paint workers occupationally exposed to organic solvents
- Expression of CYP2E1 in Human Lung and Kidney during Development and in Full‐Term Placenta: A Differential Methylation of the Gene is Involved in the …
- Expression of CYP2E1 in human nasopharynx and its metabolic effect in vitro
- Expression of CYP2E1 increases oxidative stress and induces apoptosis of cardiomyocytes in transgenic mice
- Expression of cytochrome P450 enzymes CYP1A1, CYP1B1, CYP2E1 and CYP4B1 in cultured transitional cells from specimens of the human urinary tract and from …
- Expression of human CYP2E1 in insect cells using bac-to-bac expression system
- Expression, catalytic activity, and inducibility of cytochrome P450 2E1 (CYP2E1) in the rat central nervous system
- Extrahepatic metabolism by CYP2E1 in PBPK modeling of lipophilic volatile organic chemicals: impacts on metabolic parameter estimation and prediction of dose …
- Fast CYP2E1 genotyping using automated fluorescent detection.
- Featured structure-activity relationships for some tri-and tetrachlorobiphenyls in human CYP2E1-activated mutagenicity—Impact of the extent of ortho-chlorination
- Ferric citrate CYP2E1-independently promotes alcohol-induced apoptosis in HepG2 cells via oxidative/nitrative stress which is attenuated by pretreatment with …
- final hydrogenated metabolites of curcumin, possess superior hepatic-protective effect against acetaminophen-induced liver injury: role of CYP2E1 and Keap1-Nrf2 …
- for the Expression of Recombinant Human Cytochrome P450s inEscherichia coliUsing Bacterial Signal Peptides: Expression of CYP3A4, CYP2A6, and CYP2E1
- Formation of multiple CYP2E1 complexes affects activity
- Frequencies of genotypes and alleles of the functional SNPs in CYP2C19 and CYP2E1 in mainland Chinese Kazakh, Uygur and Han populations
- Frequency distribution of high risk alleles of CYP2C19, CYP2E1, CYP3A4 genes in Haryana population
- Functional analyses of the pig CYP2E1 promoter and identification of the transcription factors required for CYP2E1 expression
- CYP2E1_methylation_in.1048.aspx”>Functional correlate of CYP2E1 methylation in chronic exposure to VOCs: promoter methylation vs. 5’UTR methylation
- Functional CYP2E1 is required for substantial in vivo formation of 2,5-hexanedione from n-hexane in the mouse
- Functional polymorphism in porcine CYP2E1 gene: Its association with skatole levels
- Functional polymorphism of CYP2E1 gene and alcohol use disorders in a Tibetan population.
- Gadolinium chloride blocks alcohol-dependent liver toxicity in rats treated chronically with intragastric alcohol despite the induction of CYP2E1
- Garlic oil alleviated ethanol-induced fat accumulation via modulation of SREBP-1, PPAR-α, and CYP2E1
- Gene copy number variation analysis reveals dosage-insensitive expression of CYP2E1
- Gene CYP2E1 expression in mouse liver cells exposed to low-dose radiation
- Gene Structure and Multiple Regulations of the Ethanol-Inducible Cytochrome P45O2E1 (CYP2E1) Subfamily
- Gene–environmental interactions between alcohol-drinking behavior and ALDH2 and CYP2E1 polymorphisms and their impact on micronuclei frequency in human …
- Genetic and dietary predictors of CYP2E1 activity: a phenotyping study in Hawaii Japanese using chlorzoxazone
- Genetic Interaction between NAT2, GSTM1, GSTT1, CYP2E1, and Environmental Factors Is Associated with Adverse Reactions to Anti-Tuberculosis Drugs
- Genetic polymorphism analysis of cytochrome P4502E1 (CYP2E1) in a Chinese Tibetan population
- Genetic polymorphism analysis of cytochrome P4502E1 (CYP2E1) in Chinese Han populations from four different geographic areas of Mainland China
- Genetic polymorphism in CYP2E1: Population distribution of CYP2E1 activity
- Genetic Polymorphism in Promoter Sequence of CYP2E1 Gene in Paint Manufacturing Workers Exposed to Volatile Organic Compounds
- Genetic polymorphism of CYP2D6, CYP2E1 and susceptibility to chronic occupational manganism poisoning [J]
- Genetic polymorphism of CYP2E1 and digestive tract alcohol damage among Polish individuals
- Genetic polymorphism of CYP2E1, ADH2, and ALDH2 in Mexican-Americans
- CYP2E1,_GSTT1_M1_and_NQO1.905.aspx”>Genetic Polymorphism of CYP2E1, GSTT1/M1 and NQO1 on Biomarker of Urinary Spma Among Benzene-Exposed Workers
- Genetic polymorphism of cytochrome P450 (CYP) 1A1, CYP1A2, and CYP2E1 genes modulate susceptibility to gastric cancer in patients with Helicobacter …
- Genetic polymorphism of GSTM1, CYP2E1 and CYP2D6 in Egyptian bladder cancer patients
- Genetic polymorphism of human CYP2E1: characterization of two variant alleles
- Genetic polymorphism of human CYP2E1: new allels detected in exons and exon-intron junctions
- Genetic polymorphism of the CYP1A1, CYP2E1, GSTM1 and GSTT1 genes and lung cancer susceptibility in a north Indian population
- Genetic polymorphism of the CYP2E1 gene and susceptibility to Parkinson’s disease in Taiwanese
- Genetic polymorphisms in CYP2E1: association with schizophrenia susceptibility and risperidone response in the Chinese Han population
- Genetic polymorphisms in cytochrome P450 (CYP) 1A1, CYP1A2, CYP2E1, glutathione S-transferase (GST) M1 and GSTT1 and susceptibility to prostate cancer in the …
- Genetic polymorphisms in GSTM1,-P1,-T1, and CYP2E1 and the risk of adult brain tumors
- Genetic Polymorphisms of ADH1C and CYP2E1 and Risk of Oral Squamous Cell Carcinoma
- Genetic polymorphisms of alcohol inducible CYP2E1 in Turkish population
- Genetic Polymorphisms of CYP1A1, CYP2E1, and GSTM1 Genes: Susceptibility to Colon Cancer
- Genetic polymorphisms of CYP1A1, CYP2E1, GSTM1, and GSTT1 associated with head and neck cancer
- Genetic polymorphisms of CYP2D6, CYP1A1 and CYP2E1 in the South-Amerindian population of Chile.
- Genetic polymorphisms of CYP2E1 and DNA repair genes HOGG1 and XRCC1: association with hepatitis B related advanced liver disease and cancer
- Genetic polymorphisms of CYP2E1 and GSTM1 and T1 on susceptibility to esophageal cancer in Huaian, China
- Genetic polymorphisms of CYP2E1 and GSTM1 loci and susceptibility to anti-tuberculosis drug-induced hepatotoxicity
- Genetic polymorphisms of CYP2E1 and risk of colorectal adenomas in the Self Defense Forces Health Study
- Genetic polymorphisms of CYP2E1 and risk of colorectal cancer: the Fukuoka Colorectal Cancer Study
- Genetic polymorphisms of CYP2E1, GST, and NAT2 enzymes are not associated with risk of breast cancer in a sample of Lebanese women
- Genetic polymorphisms of CYP2E1, GSTM1, and GSTT1; environmental factors and risk of oral cancer.
- Genetic polymorphisms of CYP2E1, GSTT1, GSTP1, GSTM1, ALDH2, and ODC and the risk of advanced precancerous gastric lesions in a Chinese population
- Genetic Polymorphisms of Genes Coding to Alcohol‐Metabolizing Enzymes in Western Mexicans: Association of CYP2E1*c2/CYP2E1*5B Allele with Cirrhosis and …
- Genetic polymorphisms of NAT2 and CYP2E1 associated with antituberculosis drug-induced hepatotoxicity in Korean patients with pulmonary tuberculosis
- Genetic Polymorphisms of NAT2, CYP2C9, CYP2C19, CYP2D6 and CYP2E1, and Antituberculosis Drugs Induced Maculopapular Eruption
- Genetic polymorphisms of NAT2, CYP2E1 and GST enzymes and the occurrence of antituberculosis drug-induced hepatitis in Brazilian TB patients
- Genetic Polymorphisms of SLCO1B1, CYP2E1 and UGT1A1 and Susceptibility to Anti-Tuberculosis Drug-Induced Hepatotoxicity: A Chinese Population-Based …
- Genetic regulation of liver microsomal CYP2E1 activity among strains of the viviparous fishes Poeciliopsis occidentalis and Poeciliopsis lucida
- Genetic Repeat Polymorphism in the Regulating Region of CYP2E1: Frequency and Relationship With Enzymatic Activity in Alcoholics
- Genetic Variability in CYP2E1 and Catalase Gene Among Currently and Formerly Alcohol-Dependent Male Subjects
- Genetic variants of ALDH2-rs671 and CYP2E1-rs2031920 contributed to risk of hepatocellular carcinoma susceptibility in a Chinese population
- Genetic variation in the temperature dependence of liver microsomal CYP2E1 activity, within and between species of the viviparous fish Poeciliopsis
- Genetic variations of NAT2 and CYP2E1 and isoniazid hepatotoxicity in a diverse population
- Genotoxicity of 1‐methylpyrene and 1‐hydroxymethylpyrene in chinese hamster V79‐derived cells expressing both human CYP2E1 and SULT1A1
- Genotype and allele frequencies of polymorphic CYP2E1 in the Turkish population
- Genotype and allele frequencies of polymorphic cytochromes P450 CYP1A2 and CYP2E1 in Mexicans
- Genotype and allelic frequencies of CYP2E1* 5B polymorphism in the southwest population of Iran
- Genotype and phenotype polymorphisms of NAT2 and CYP2E1 in the Han Chinese pediatric population
- Genotype Polymorphisms of NAT2 and CYP2E1 Genes Associated with Drug Induced Liver Injury (DILI) in Indonesian Tuberculosis Patients
- Global Analysis of Protein− Protein Interactions Reveals Multiple CYP2E1− Reductase Complexes
- Global patterns of variation in allele and haplotype frequencies and linkage disequilibrium across the CYP2E1 gene
- Glucose inhibition of the induction of CYP2E1 mRNA expression by ethanol in FGC-4 cells
- Glucoside exacerbates acetaminophen-induced hepatotoxicity by inducing hepatic expression of CYP2E1, CYP3A4 and CYP1A2
- Glutathione depletion in CYP2E1-expressing liver cells induces toxicity due to the activation of p38 mitogen-activated protein kinase and reduction of nuclear factor-κB …
- Glycyrrhetinic acid prevents acetaminophen-induced acute liver injury via the inhibition of CYP2E1 expression and HMGB1-TLR4 signal activation in mice
- Green tea polyphenol epigallocatechin-3-gallate protects HepG2 cells against CYP2E1-dependent toxicity
- Growth retardation of fetal rats exposed to nicotine in utero: Possible involvement of CYP1A1, CYP2E1, and P‐glycoprotein
- GSTT1 and CYP2E1 polymorphisms and trihalomethanes in drinking water: effect on childhood leukemia.
- GSTT1, GSTM1 and CYP2E1 genetic polymorphisms in gastric cancer and chronic gastritis in a Brazilian population
- GYKI-47261, a new AMPA [2-amino-3-(3-hydroxymethylisoxazole-4-yl) propionic acid] antagonist, is a CYP2E1 inducer
- Halothane inhalation inhibits the metabolism of chlorzoxazone, a substrate for CYP2E1, in rabbits
- HBx inhibits CYP2E1 gene expression via downregulating HNF4α in human hepatoma cells
- Helicobacter pylori infection, but not genetic polymorphism of CYP2E1, is highly prevalent in gastric cancer patients younger than 40 years
- Hepatic and pulmonary microsomal benzene metabolism in CYP2E1 knockout mice
- Hepatocyte CYP2E1 overexpression and steatohepatitis lead to impaired hepatic insulin signaling
- Hepatoprotective effect of 10% ethanolic extract from Curdrania tricuspidata leaves against ethanol-induced oxidative stress through suppression of CYP2E1
- Hepatoprotective Effect of Punica granatum Seed Oil Extract on Paracetamol Intoxication in Rat Via Inhibory Effect of CYP2E1
- Hepatotoxicity Mediated by Pyrazole (CYP2E1) Plus TNF-α Treatment Occurs in jnk2−/− but not in jnk1−/− Mice
- Heteromeric complex formation between CYP2E1 and CYP1A2: evidence for the involvement of electrostatic interactions
- High CYP2E1 activity aggravates hepatofibrosis by limiting macrophage polarization towards the M2 phenotype
- High CYP2E1 activity correlates with hepatofibrogenesis induced by nitrosamines
- High dose lycopene supplementation increases hepatic CYP2E1 protein and TNF‐α expression in alcohol fed rats
- High inducibility of mouse renal CYP2E1 gene by tobacco smoke and its possible effect on DNA single strand breaks
- Higher sensitivity of female cells to ethanol: methylation of DNA lowers CYP2E1, generating more ROS
- Histone acetylation and arachidonic acid cytotoxicity in HepG2 cells overexpressing CYP2E1
- Histone modification-mediated CYP2E1 gene expression and apoptosis of HepG2 cells
- Homology modelling of human CYP2E1 based on the CYP2C5 crystal structure: investigation of enzyme–substrate and enzyme–inhibitor interactions
- Hormone controlled phosphorylation and degradation of CYP2B1 and CYP2E1 in isolated rat hepatocytes
- How mutations affecting the ligand-receptor interactions: a combined MD and QM/MM calculation on CYP2E1 and its two mutants
- Human CYP2A6, CYP2B6, and CYP2E1 atropselectively metabolize polychlorinated biphenyls to hydroxylated metabolites
- Human CYP2E1 is regulated by miR-378
- Human CYP2E1 mediates the formation of glycidamide from acrylamide
- Human CYP2E1-activated mutagenicity of dioxin-like PCBs 105 and 118—Experimental data consistent with molecular docking results
- Human CYP2E1-dependent and human sulfotransferase 1A1-modulated induction of micronuclei by benzene and its hydroxylated metabolites in Chinese hamster …
- Human CYP2E1‐dependent mutagenicity of benzene and its hydroxylated metabolites in V79‐derived cells: Suppression and enhancement by ethanol pretreatment
- Human CYP2E1-dependent mutagenicity of mono-and dichlorobiphenyls in Chinese hamster (V79)-derived cells
- Human cytochrome P450 2E1 (CYP2E1): from genotype to phenotype.
- Human hepatic CYP2E1 expression during development
- Human hepatocytes are protected from ethanol-induced cytotoxicity by DADS via CYP2E1 inhibition
- Human placental lactogen induces CYP2E1 expression via PI 3-kinase pathway in female human hepatocytes
- Human variability for metabolic pathways with limited data (CYP2A6, CYP2C9, CYP2E1, ADH, esterases, glycine and sulphate conjugation)
- Hypomethylation and hypoexpression of human CYP2E1 gene in lung tumors
- Identification and characterization of a mitochondrial targeting signal in rat cytochrome P450 2E1 (CYP2E1)
- Identification and functional analysis of a novel human CYP2E1 far upstream enhancer
- Identification of 2-piperidone as a biomarker of CYP2E1 activity through metabolomic phenotyping
- Identification of a 16-nucleotide sequence that mediates post-transcriptional regulation of rat CYP2E1 by insulin
- Identification of a critical CYP2E1 epitope in patients with drug-induced liver injury from anesthetics (93.16)
- Identification of CYP2E1 in marmoset monkey
- Identification of CYP2E1-dependent genes involved in carbon tetrachloride-induced hepatotoxicity
- Identification of cytochrome CYP2E1 as critical mediator of alcohol effects on steatotic hepatocytes
- Identification of cytochrome CYP2E1 as critical mediator of synergistic effects of alcohol and cellular lipid accumulation in hepatocytes in vitro
- Identification of deletions and duplications in the CYP2E1 gene in a population in Goiânia–GO by MLPA.
- Identification of inhibitory component in cinnamon—o-methoxycinnamaldehyde inhibits cyp1a2 and CYP2E1—
- Identification of Novel CYP2E1 Inhibitor to Investigate Cellular and Exosomal CYP2E1-Mediated Toxicity
- Identification of novel toxicity-associated metabolites by metabolomics and mass isotopomer analysis of acetaminophen metabolism in wild-type and CYP2E1-null …
- Identification of sequences responsible for intracellular targeting and membrane binding of rat CYP2E1 in yeast
- IL-4 promotes experimental drug-induced hepatitis by reducing immune responses to haptenated proteins and inhibiting regulatory responses to native CYP2E1 …
- IL-4-mediated transcriptional regulation of human CYP2E1 by two independent signaling pathways
- Immunohistochemical demonstration of the expression of CYP2E1 in human breast tumour and non-tumour tissues
- Immunohistochemical Detection of CYP2E1 and 2-S-Glutathionyl Acetate in Murine Lung Tumors: Diminished Formation of Reactive Intermediates of 1,1 …
- Immunohistochemical study of CYP2E1 in hepatocellular carcinoma carcinogenesis: examination with newly prepared anti-human CYP2E1 antibody
- Immunological detection of CYP2E1 in fresh rat lymphocytes and its pretranslational induction by fasting
- Impact of CYP2E1 genotype in renal cell and urothelial cancer patients
- Impact of CYP2E1 polymorphisms on the risk of esophageal cancer
- Impact of CYP2E1, GSTA1 and GSTP1 gene variants on serum alpha glutathione S-transferase level in patients undergoing anaesthesia
- Impairment of Akt activity by CYP2E1 mediated oxidative stress is involved in chronic ethanol-induced fatty liver
- Implication of xenobiotic metabolizing enzyme gene (CYP2E1, CYP2C19, CYP2D6, mEH and NAT2) polymorphisms in breast carcinoma
- in rats induced by aqueous extract of Polygoni Multiflori Radix, root of Polygonum multiflorum related to the activity inhibition of CYP1A2 or CYP2E1
- in urea in conjunction with L-arginine metabolism in the liver leads to induction of cytochrome P450 2E1 (CYP2E1): The role of urea in CYP2E1 induction by acute …
- In vitro evaluation of structural analogs of diallyl sulfide as novel CYP2E1 inhibitors for their protective effect against xenobiotic-induced toxicity and HIV …
- In vitro inhibition of human CYP2E1 and CYP3A by quercetin and myricetin in hepatic microsomes is not gender dependent
- In vitro metabolism of styrene to styrene oxide in liver and lung of CYP2E1 knockout mice
- In vivo and in vitro characterization of chlorzoxazone metabolism and hepatic CYP2E1 levels in African Green monkeys: induction by chronic nicotine treatment
- In vivo and in vitro characterization of CYP2E1 activity in Japanese and Caucasians.
- In vivo CYP2E1 phenotyping as a new potential biomarker of occupational and experimental exposure to benzene
- Inactivation of cytochrome P-450 (CYP2E1) and carboxylesterase (hydrolase A) enzymes by vinyl carbamate in murine pulmonary microsomes
- Inactivation of hepatic CYP2E1 by an epoxide of diallyl sulfone
- Inactivation of stress protein p8 increases murine carbon tetrachloride hepatotoxicity via preserved CYP2E1 activity
- Increase expression of CYP2E1 mRNA after methamphetamine administration in rats
- Increased bioaccumulation of urethane in CYP2E1-/-versus CYP2E1+/+ mice
- Increased Expression of CYP2E1 gene in gastric cancer may be a molecular marker for mazandaran province population
- Increased hepatocyte CYP2E1 expression in a rat nutritional model of hepatic steatosis with inflammation
- Increased prooxidant production and enhanced susceptibility to glutathione depletion in HepG2 cells co‐expressing HCV core protein and CYP2E1
- Increased toxicity by transforming growth factor-beta 1 in liver cells overexpressing CYP2E1
- Independent and combined effects of ethanol self-administration and nicotine treatment on hepatic CYP2E1 in African green monkeys
- Individual variability of CYP2E1 xenobiotic oxidation in human liver
- Induction and recovery time course of rat brain CYP2E1 after nicotine treatment
- Induction and regulation of CYP2E1 in murine liver after acute and chronic acetone administration.
- Induction of brain CYP2E1 by chronic ethanol treatment and related oxidative stress in hippocampus, cerebellum, and brainstem
- Induction of brain CYP2E1 changes the effects of ethanol on dopamine release in nucleus accumbens shell
- Induction of catalase, alpha, and microsomal glutathione S‐transferase in CYP2E1 overexpressing HepG2 cells and protection against short‐term oxidative stress
- Induction of CYP1A1 and CYP2E1 in rat liver by histamine: binding and kinetic studies
- Induction of CYP2B and CYP2E1 in precision-cut rat liver slices cultured in defined medium
- Induction of CYP2E1 activity in Ctenopharyngodon idellus hepatocyte
- Induction of CYP2E1 activity in liver transplant patients as measured by chlorzoxazone 6‐hydroxylation
- Induction of CYP2E1 in liver, kidney, brain and intestine during chronic ethanol administration and withdrawal: evidence that CYP2E1 possesses a rapid phase half …
- Induction of CYP2E1 in non-alcoholic fatty liver diseases
- Induction of CYP2E1 in testes of isoniazid-treated rats as possible cause of testicular disorders
- Induction of DNA strand breaks and oxidative stress in HeLa cells by ethanol is dependent on CYP2E1 expression
- Induction of hepatic CYP2E1 by a subtoxic dose of acetaminophen in rats: increase in dichloromethane metabolism and carboxyhemoglobin elevation
- Induction of nicotine-metabolizing CYP2B1 by ethanol and ethanol-metabolizing CYP2E1 by nicotine: summary and implications
- Induction of rat hepatic CYP2E1 expression by arecoline in vivo
- Induction of SIRT1 by melatonin improves alcohol‐mediated oxidative liver injury by disrupting the CRBN‐YY1‐CYP2E1 signaling pathway
- Influence of Acarbose, Metformin and Pioglitazone on TNF-αand CYP2E1 in Liver Tissue of NAFLD Rat
- Influence of CYP1A1, CYP2E1, GSTM3 and NAT2 genetic polymorphisms in oral cancer susceptibility: results from a case-control study in Rio de Janeiro
- INFLUENCE OF GENETIC ADMIXTURE ON POLYMORPHISMS OF ALCOHOL-METABOLIZING ENZYMES: ANALYSES OF MUTATIONS ON THE CYP2E1, ADH2, ADH3 AND …
- Influence of genetic admixture on polymorphisms of drug‐metabolizing enzymes: Analyses of mutations on NAT2 and CYP2E1 genes in a mixed Hispanic …
- Influence of GSTs, CYP2E1 and mEH polymorphisms on 1, 3-butadiene-induced micronucleus frequency in Chinese workers
- Influence of GSTT1, mEH, CYP2E1 and RAD51 polymorphisms on diepoxybutane-induced SCE frequency in cultured human lymphocytes
- Influence of NQO1, ALDH2, and CYP2E1 genetic polymorphisms, smoking, and alcohol drinking on the risk of lung cancer in Koreans
- Influence of selected inhibitors on the metabolism of the styrene metabolite 4-vinylphenol in wild-type and CYP2E1 knockout mice
- Inhibition of autophagy promotes CYP2E1-dependent toxicity in HepG2 cells via elevated oxidative stress, mitochondria dysfunction and activation of p38 and …
- Inhibition of chlorzoxazone metabolism, a clinical probe for CYP2E1, by a single ingestion of watercress
- Inhibition of chlorzoxazone metabolism, a clinical probe for CYP2E1, by a single-dose watercress ingestion; comparison with one week isoniazid treatment
- Inhibition of CYP2E1 activity does not abolish pulsatile urine alcohol concentrations during chronic alcohol infusions
- Inhibition of CYP2E1 and activation of Nrf2 signaling pathways by a fraction from Entada africana alleviate carbon tetrachloride-induced hepatotoxicity
- Inhibition of CYP2E1 attenuates chronic alcohol intake-induced myocardial contractile dysfunction and apoptosis
- Inhibition of CYP2E1 attenuates myocardial dysfunction in a murine model of insulin resistance through NLRP3-mediated regulation of mitophagy
- Inhibition of CYP2E1 by chlormethiazole as measured by chlorzoxazone pharmacokinetics in patients with alcoholism and in healthy volunteers
- Inhibition of CYP2E1 catalytic activity in vitro by S-adenosyl-L-methionine
- CYP2E1-expression-by-androstenone-relation-to-boar-taint”>Inhibition of CYP2E1 expression by androstenone: Relation to boar taint
- Inhibition of CYP2E1 leads to decreased advanced glycated end product formation in high glucose treated ADH and CYP2E1 over-expressing VL-17A cells
- Inhibition of CYP2E1 leads to decreased malondialdehyde–acetaldehyde adduct formation in VL-17A cells under chronic alcohol exposure
- Inhibition of CYP2E1 Reverses CD4+ T-Cell Alterations in Trichloroethylene-Treated MRL+/+ Mice
- Inhibition of CYP2E1 with natural agents may be a feasible strategy for minimizing the hepatotoxicity of ethanol
- Inhibition of CYP2E1 With Propylene Glycol Does Not Protect Against Hepatocellular Injury in Human Acetaminophen Daily‐Dosing Model
- Inhibition of CYP3A, CYP1A and CYP2E1 activities by resveratrol and other non volatile red wine components
- Inhibition of cytochrome P450 enzymes participating in p-nitrophenol hydroxylation by drugs known as CYP2E1 inhibitors
- Inhibition of Ethanol-induced CYP2E1 by Curcuma longa L. Extract
- Inhibition of rat hepatic CYP2E1 by quinacrine: molecular modeling investigation and effects on 4-(methyl nitrosamino)-1-(3-pyridyl)-1-butanone (NNK)-induced …
- Inhibition of Urethane-Induced Carcinogenicity in CYP2E1−/− in Comparison to CYP2E1+/+ Mice
- Inhibition of Urethane-Induced Carcinogenicity in CYP2E1-/-Vs. CYP2E1+/+ Mice
- Inhibition of urethane-induced genotoxicity and cell proliferation in CYP2E1-null mice
- Inhibitory effects of cytochrome P450 enzymes CYP1A2, CYP2A6, CYP2E1 and CYP3A4 by extracts and alkaloids of Gelsemium elegans roots
- Inhibitory potency of 4-carbon alkanes and alkenes toward CYP2E1 activity
- Insertion polymorphism of CYP2E1 and urinary N -methylformamide after N,N - dimethylformamide exposure in Japanese workers
- Insertion Polymorphism of the CYP2E1 Gene in Patients with Infiltrative Pulmonary Tuberculosis from Bashkortostan
- Insertional polymorphism of the CYP2E1 gene in infiltrative pulmonary tuberculosis in populations of Bashkortostan Republic
- Insights into insulin-mediated regulation of CYP2E1: miR 132/212 targeting of CYP2E1 and role of PI3-K, Akt, mTOR signaling in regulating miR132/212 and miR 122 …
- Insights into insulin-mediated regulation of CYP2E1: miR-132/-212 targeting of CYP2E1 and role of phosphatidylinositol 3-kinase, Akt (protein kinase B), mammalian …
- Insulin effects on CYP2E1, 2B, 3A, and 4A expression in primary cultured rat hepatocytes
- Insulin signaling in the transcriptional and posttranscriptional regulation of CYP2E1 expression
- Interaction between genetic polymorphisms of CYP2E1 & NAT1 and smoking in lung cancer development (Preliminary report)
- Interaction between Polymorphisms in CYP2E1 Rsa Ⅰ Genotypes and Lifestyle with Risk of Stomach Cancer
- Interaction of polymorphisms of CYP2E1 and environmental risk factors in gastric cancer
- Interactions between CYP2E1 and CYP2B4: effects on affinity for NADPH-cytochrome P450 reductase and substrate metabolism
- Interactions between CYP2E1, GSTZ1 and GSTT1 polymorphisms and exposure to drinking water trihalomethanes and their association with semen quality
- Interindividual variability of chlorzoxazone 6‐hydroxylation in men and women and its relationship to CYP2E1 genetic polymorphisms
- Interleukin-6 mediated upregulation of CYP1B1 and CYP2E1 in colorectal cancer involves DNA methylation, miR27b and STAT3
- Intestinal CYP2E1: A mediator of alcohol-induced gut leakiness
- Investigation of bioactivation and toxicity of styrene in CYP2E1 transgenic cells
- Investigation of indazole unbinding pathways in CYP2E1 by molecular dynamics simulations
- Investigation of the inhibition of eight major human cytochrome P450 isozymes by a probe substrate cocktail in vitro with emphasis on CYP2E1
- Investigation of xenobiotics metabolism, genotoxicity, and carcinogenicity using CYP2E1-/-mice
- In-Vitro CYP3A4, CYP2E1 and UGT Activity in Human Liver Microsomes by Strobilanthes crispus Leaf Extracts
- Involvement of CYP2E1 and carboxylesterase enzymes in vinyl carbamate metabolism in human lung microsomes
- Involvement of CYP2E1 as a low-affinity enzyme in phenacetin O-deethylation in human liver microsomes
- Involvement of CYP2E1 in the course of brain edema induced by subacute poisoning with 1, 2-Dichloroethane in mice
- Involvement of hepatic stellate cell cytoglobin in acute hepatocyte damage through the regulation of CYP2E1-mediated xenobiotic metabolism
- Iron and CYP2E1-dependent oxidative stress and toxicity
- Isolation of the mouse cytochrome P450J (CYP2E1) cDNA and its reciprocal testosterone regulation in kidney and liver
- Isozyme-selective metabolism of ethyl carbamate by cytochrome P450 (CYP2E1) and carboxylesterase (hydrolase A) enzymes in murine liver microsomes
- Kaempferol’s protective effect on ethanol-induced mouse primary hepatocytes injury involved in the synchronous inhibition of SP1, Hsp70 and CYP2E1
- Kinetic characterization of CYP2E1 inhibition in vivo and in vitro by the chloroethylenes
- Kinetic characterizations of diallyl sulfide analogs for their novel role as CYP2E1 enzyme inhibitors
- Kupffer cell inactivation alleviates ethanol-induced steatosis and CYP2E1 induction but not inflammatory responses in rat liver
- Lack of association of CYP2E1 and CYP1A1 polymorphisms with osteoporosis in postmenauposal women
- Lack of common mutation in the alfa-subunit of the mitochondrial trifunctional protein and the polymorphism of CYP2E1 in three Japanese women with acute fatty liver …
- Lack of correlation between lymphocytic mrna expression and activity of CYP3A4 and CYP2E1 In‐vivo in alcoholics and non‐alcoholics
- Lack of cytochrome P450 2E1 (CYP2E1) induction in the rat liver by starvation without coprophagy
- Lipid peroxidation, CYP2E1 and arachidonic acid metabolism in alcoholic liver disease in rats
- Lipopolysaccharide induces CYP2E1 in astrocytes through MAP kinase kinase-3 and C/EBPβ and-δ
- Lipopolysaccharide-induced liver injury in rats treated with the CYP2E1 inducer pyrazole
- Liver cancer-related gene CYP2E1 expression in HBV transgenic mice with acute liver injury
- Liver nuclear and microsomal CYP2E1-mediated metabolism of xenobiotics in rats chronically drinking an alcohol-containing liquid diet
- Losartan effects on liver cytochromes CYP3A, CYP2C and CYP2E1 functioning at metabolic syndrome in young and adult rats
- Loss of CYP2E1 and CYP1A2 activity as a function of acetaminophen dose: relation to toxicity
- Low doses of curcumin protect alcohol-induced liver damage by modulation of the alcohol metabolic pathway, CYP2E1 and AMPK
- Low doses of nicotine and ethanol induce CYP2E1 and chlorzoxazone metabolism in rat liver
- Low-dose diethyldithiocarbamate attenuates the hepatotoxicity of 1, 3-dichloro-2-propanol and selectively inhibits CYP2E1 activity in the rat
- Lung cancer risk in relation to the CYP2E1 Rsa I genetic polymorphism among African-Americans and Caucasians in Los Angeles County.
- Lycopene attenuates alcoholic apoptosis in HepG2 cells expressing CYP2E1
- Lycopene attenuates arachidonic acid toxicity in HepG2 cells overexpressing CYP2E1
- Lymphocyte cytochrome P450-CYP2E1 expression in human IDDM subjects
- M1 Polarization bias and subsequent NASH progression is attenuated by nitric oxide donor DETA NONOate via inhibition of CYP2E1 induced oxidative stress in …
- Major tanshinones of Danshen (Salvia miltiorrhiza) exhibit different modes of inhibition on human CYP1A2, CYP2C9, CYP2E1 and CYP3A4 activities in vitro
- Malotilate, a hepatoprotectant, suppresses CYP2E1 expression in rats
- Mammalian CYP2E1 gene triggered changes of relative ions fluxes, CaM content and genes expression profiles in Petunia hybrida cells to enhance resistance to …
- Mammalian cytochrome CYP2E1 triggered differential gene regulation in response to trichloroethylene (TCE) in a transgenic poplar
- Mannan‐binding lectin attenuates acetaminophen‐induced hepatotoxicity by regulating CYP2E1 expression via ROS‐dependent JNK/SP1 pathway
- Maternal protein restriction during lactation modulated the expression and activity of rat offspring hepatic CYP1A1, CYP1A2, CYP2B1, CYP2B2, and CYP2E1 …
- MATERNAL SMOKING, POLYMORPHISMS IN CYP1A1, CYP2E1, EPHX1, NAT2, NQO1, AND CHILDHOOD ACUTE LEUKEMIA
- Mechanism and clinical significance of HBx-mediated inhibition of CYP2E1 expression in the human HepG2 hepatoma cell line
- mechanism of Wu-Zi-Yan-Zong-Wan, a traditional Chinese herbal formula, against alcohol-induced oxidative damage in CYP2E1 cDNA-transfected HepG2 (E47) …
- Mechanism-based inactivation of human CYP2E1 by diethyldithocarbamate
- Mechanisms of down-regulation of CYP2E1 expression by inflammatory cytokines in rat hepatoma cells
- Meta-analysis of CYP2E1 polymorphisms in liver carcinogenesis
- Meta-analysis on the relationship between CYP2E1 genetic polymorphism and susceptibility to hepatocellular carcinoma in Chinese
- Metabolic activation by human arylacetamide deacetylase, CYP2E1, and CYP1A2 causes phenacetin-induced methemoglobinemia
- Metabolic activation of dacarbazine by human cytochromes P450: the role of CYP1A1, CYP1A2, and CYP2E1
- Metabolic activation of N-alkylnitrosamines in genetically engineered Salmonella typhimurium expressing CYP2E1 or CYP2A6 together with human NADPH …
- Metabolic activation of o-phenylphenol to a major cytotoxic metabolite, phenylhydroquinone: role of human CYP1A2 and rat CYP2C11/CYP2E1
- Metabolic activities of cytochrome P-450 CYP2E1 and cytochrome P-450 CYP3A in hepatic alcohol-injuried rats [J]
- Metabolic oxidation and toxification of N-methylformamide catalyzed by the cytochrome P450 isoenzyme CYP2E1.
- Metabolism and toxicity of the styrene metabolite 4-vinylphenol in CYP2E1 knockout mice
- Metabolism of benzene in human liver microsomes: individual variations in relation to CYP2E1 expression
- Metabolism of dapsone to its hydroxylamine by CYP2E1 in vitro and in vivo
- Metabolism of ethyl carbamate by pulmonary cytochrome P450 and carboxylesterase isozymes: involvement of CYP2E1 and hydrolase A
- Metallothionein 2A induction by zinc protects HEPG2 cells against CYP2E1-dependent toxicity
- Method for in vivo and in vitro Evaluation of CYP2E1 Activities
- Methodology to assay CYP2E1 mixed function oxidase catalytic activity and its induction
- MicroRNA regulation of CYP 1A2, CYP3A4 and CYP2E1 expression in acetaminophen toxicity
- MicroRNA‐122 protects mice and human hepatocytes from acetaminophen toxicity by regulating CYP1A2 and CYP2E1 expression
- Microsomal ethanol oxidizing system: transcriptional and posttranscriptional regulation of cytochrome P450, CYP2E1.
- Mitochondrial CYP2E1 is sufficient to mediate oxidative stress and cytotoxicity induced by ethanol and acetaminophen
- Mitochondrial dysfunction by γ-irradiation accompanies the induction of cytochrome P450 2E1 (CYP2E1) in rat liver
- Modeling interchild differences in pharmacokinetics on the basis of subject-specific data on physiology and hepatic CYP2E1 levels: a case study with toluene
- Modification effects of GSTM1, GSTT1 and CYP2E1 polymorphisms on associations between raw salted food and incomplete intestinal metaplasia in a high‐risk …
- Modification of CYP2E1 and CYP3A4 activities in haemoglobin E-beta thalassemia patients
- Modulation of CYP2E1 metabolic activity in a cohort of confirmed caffeine ingesting pregnant women with preterm offspring
- Modulation of ethanol-mediated CYP2E1 induction by clofibrate and L-carnitine in rat liver
- Modulation of mouse P450 isoforms CYP1A2, CYP2B10, CYP2E1, and CYP3A by the environmental chemicals mirex, 2, 2-bis (p-chlorophenyl)-1, 1-dichloroethylene …
- Modulation of mRNA expression and activities of xenobiotic metabolizing enzymes, CYP1A1, CYP1A2, CYP2E1, GPx and GSTP1 by the Salicornia freitagii extract in …
- Molecular cloning and sequence analysis of hamster CYP2E1
- Molecular dynamics simulations of CYP2E1
- Molecular mechanism of trichloroethylene-induced hepatotoxicity mediated by CYP2E1
- Molecular modelling of CYP2E1 enzymes from rat, mouse and man: an explanation for species differences in butadiene metabolism and potential carcinogenicity, and …
- Molecular modelling of human CYP2E1 by homology with the CYP102 haemoprotein domain: investigation of the interactions of substrates and inhibitors within the …
- Morbidly obese patients exhibit increased CYP2E1-mediated oxidation of acetaminophen
- mRNA Expression of CYP2E1, CYP2A19, CYP1A2, HSD3B, SULT1A1 and SULT2A1 genes in surgically castrated, immunologically castrated, entire male and female …
- Multifold Activation of CYP3A4 Caused by Alcohol-Induced Increase in the Content of CYP2E1 in Human Liver Microsomes
- Mutagenic Activity of N‐Nitrosodiethylamine in Cell Lines Expressing Human CYP2E1—Adequacy of Dimethylsulfoxide as Solvent
- NADPH: CYTOCHROME P450 REDUCTASES OF VARIOUS SPECIES CAN BE USED IN SYSTEMS RECONSTITUTING DRUG-METABOLIZING CYP2E1 …
- NADPH-dependent microsomal electron transfer increases degradation of CYP2E1 by the proteasome complex: role of reactive oxygen species
- Nanoformulated SOD1 ameliorates the combined NASH and alcohol-associated liver disease partly via regulating CYP2E1 expression in adipose tissue and liver
- NAT2 and CYP2E1 polymorphisms and susceptibility to first-line anti-tuberculosis drug-induced hepatitis
- NAT2, CYP2C9, CYP2C19, and CYP2E1 genetic polymorphisms in anti-TB drug-induced maculopapular eruption
- NF-κB-mediated regulation of rat CYP2E1 by two independent signaling pathways
- N-Hydroxylation of 4-Aminobiphenyl by CYP2E1 Produces Oxidative Stress in a Mouse Model of Chemically Induced Liver Cancer
- Nicotinamide N-oxidation by CYP2E1 in human liver microsomes
- Nitric oxide donors prevent while the nitric oxide synthase inhibitor L-NAME increases arachidonic acid plus CYP2E1-dependent toxicity
- No association between polymorphisms in CYP2E1, GSTM1, NAT1, NAT2 and the risk of gastric adenocarcinoma in the European prospective investigation into …
- No association of CYP2E1 genetic polymorphisms with alcohol dependence in Han Taiwanese population
- No linkage of the cytochrome P-450IIE1 (CYP2E1) C1/C2 polymorphism to schizophrenia
- No significant expression of CYP2E1 in rat liver stellate cells
- Non-additive effects of changing the cytochrome P450 ensemble: incorporation of CYP2E1 into human liver microsomes and its impact on CYP1A2
- Noninvolvement of CYP2E1 in the (ω-1)-hydroxylation of fatty acids in rat kidney microsomes
- Non-positive autoimmune responses against CYP2E1 in refrigeration mechanics exposed to halogenated hydrocarbons
- Note of clarification of data on the association between CYP2E1 RsaI polymorphism and lung cancer risk
- Novel CYP2E1 haplotype identified in a South African cohort
- NQO1, MPO, CYP2E1, GSTT1 and GSTM1 polymorphisms and biological effects of benzene exposure—a literature review
- Nrf2 and antioxidant defense against CYP2E1 toxicity
- Nrf2 is increased by CYP2E1 in rodent liver and HepG2 cells and protects against oxidative stress caused by CYP2E1
- Obesity‐induced CYP2E1 activity in children
- Obesity-induced increase of CYP2E1 activity and its effect on disposition kinetics of chlorzoxazone in Zucker rats
- of human prenatal biosynthesis of all-trans-retinoic acid by ethanol, ethanol metabolites, and products of lipid peroxidation reactions: a possible role for CYP2E1
- of liver microsomal 7-ethoxycoumarin O-deethylation and chlorzoxazone 6-hydroxylation activities in Japanese and Caucasian subjects genotyped for CYP2E1 …
- of the accumulation of acetaldehyde from ethanol in human prenatal cephalic tissues: evaluation of the relative contributions of CYP2E1, alcohol dehydrogenase, and …
- OF THE PLANT PHENOLIC QUERCETIN ON PROTEIN AND mRNA EXPRESSIONS OF XENOBIOTIC METABOLIZING CYP1A1, CYP2E1, NQO1 AND GST …
- of twelve chlorinated aliphatic hydrocarbons upon the cell cycle of Chinese hamster cell lines: V79d-MZ and genetically engineered cell lines expressing CYP2E1
- Ontogeny of hepatic CYP1A2 and CYP2E1 expression in rat
- Ontogeny of rat CYP2E1 and CYP1A2: a characterization and a pharmacokinetic model
- Opposite action of S-adenosyl methionine and its metabolites on CYP2E1-mediated toxicity in pyrazole-induced rat hepatocytes and HepG2 E47 cells
- Opposite effects of isoniazid and fasting on the expression of CYP2E1 protein and mRNA in house musk shrew (Suncus murinus)
- Oral clefts, maternal exposure to solvents and CYP2E1 polymorphism
- overexpression of catalase in the cytosolic or mitochondrial compartment protects against toxicity caused by glutathione depletion in HepG2 cells expressing CYP2E1
- Overexpression of CYP2E1 enhances sensitivity of hepG2 cells to fas-mediated cytotoxicity
- Overexpression of CYP2E1 in mitochondria sensitizes HepG2 cells to the toxicity caused by depletion of glutathione
- Overexpression of CYP2E1 induces HepG2 cells death by the AMP kinase activator 5′-aminoimidazole-4-carboxamide-1-β-d-ribofuranoside (AICAR)
- Over-expression of CYP2E1 mRNA and protein: implications of xenobiotic induced damage in patients with de novo acute myeloid leukemia with inv (16)(p13. 1q22); …
- Oxidative stress caused by a SOD1 deficiency ameliorates thioacetamide-triggered cell death via CYP2E1 inhibition but stimulates liver steatosis
- Oxidative stress mediated toxicity exerted by ethanol-inducible CYP2E1
- Oxidative stress potentiated by diallylsulfide, a selective CYP2E1 inhibitor, in isoniazid toxic effect on rat primary hepatocytes
- Oxidative stress, toxicology, and pharmacology of CYP2E1
- p53 mutation spectrum in relation to GSTM1, CYP1A1 and CYP2E1 in surgically treated patients with non-small cell lung cancer.
- Panax vietnamensis protects mice against carbon tetrachloride-induced hepatotoxicity without any modification of CYP2E1 gene expression
- patients treated for TB in Xinjiang Uyghur autonomous region, China, and its association with hepatic enzyme polymorphisms nat2, CYP2E1, gstm1 and gstt1
- Persimmon vinegar and its fractions protect against alcohol-induced hepatic injury in rats through the suppression of CYP2E1 expression
- Pharmacokinetic consequences of induction of CYP2E1 by ligand stabilization
- Pharmacokinetics of chlorzoxazone in rats with diabetes: induction of CYP2E1 on 6-hydroxychlorzoxazone formation
- Pharmacokinetics of drug interactions due to ligand stabilization of CYP2E1.
- Pharmacokinetics of theophylline in diabetes mellitus rats: induction of CYP1A2 and CYP2E1 on 1, 3-dimethyluric acid formation
- Pharmacological blockage of CYP2E1 and alcohol-mediated liver cancer: is the time ready?
- Phenobarbital induces monkey brain CYP2E1 protein but not hepatic CYP2E1, in vitro or in vivo chlorzoxazone metabolism
- Phenotype distribution and gender-related differences of CYP2E1 activity in a Chinese population
- Phorbol ester induces CYP2E1 in astrocytes, through a protein kinase C‐and tyrosine kinase‐dependent mechanism
- Phosphorylation of cytochrome P4502E1 (CYP2E1) by calmodulin dependent protein kinase protein kinase C and cAMP dependent protein kinase
- Phyllanthus urinaria extract attenuates acetaminophen induced hepatotoxicity: involvement of cytochrome P450 CYP2E1
- PI3K inhibitors reverse the suppressive actions of insulin on CYP2E1 expression by activating stress-response pathways in primary rat hepatocytes
- Placental DNA methylation levels at CYP2E1 and IRS2 are associated with child outcome in a prospective autism study
- Plasma exosomes exacerbate alcohol-and acetaminophen-induced toxicity via CYP2E1 pathway
- Polimorfismos en los genes de la enzima alcohol deshidrogenasa (ADH1) y la citocromo P450 2E1 (CYP2E1) en pacientes con cirrosis y carcinoma …
- Polimorfismos nos genes NAT2, CYP2E1, GSTT1, GSTM1 e ABCB11 e hepatotoxicidade induzida pela isoniazida
- Polydatin protects rat liver against ethanol-induced injury: involvement of CYP2E1/ROS/Nrf2 and TLR4/NF-B p65 pathway
- Polymorphism in CYP1A1 and CYP2E1 genes and susceptibility to leukoplakia in Indian tobacco users
- Polymorphism in cytochrome P450 CYP2D6, CYP1A1, CYP2E1 and glutathione S-transferase, GSTM1, GSTM3, GSTT1 and susceptibility to tobacco-related cancers …
- Polymorphism of CYP2E1 gene and the risk of lung cancer among African-Americans and Caucasians in Los Angeles County (California).
- Polymorphism of metabolizing genes and lung cancer histology: prevalence of CYP2E1 in adenocarcinoma
- Polymorphism of the 5′‐Flanking Region of the CYP2E1 Gene: An Association Study With Alcoholism
- Polymorphisms in CYP2E1, GSTM1 and GSTT1 and anti-tuberculosis drug-induced hepatotoxicity
- Polymorphisms in detoxification genes CYP1A1, CYP2E1, GSTT1 and GSTM1 in gastric cancer susceptibility
- Polymorphisms in glutathione S‐transferases GSTM1, GSTT1 and GSTP1 and cytochromes P450 CYP2E1 and CYP1A1 and susceptibility to cirrhosis or …
- Polymorphisms in GSTM1, CYP1A1, CYP2E1, and CYP2D6 are Associated with Susceptibility and Chemotherapy Response in Non-small-cell Lung Cancer …
- Polymorphisms in GSTT1, GSTZ1, and CYP2E1, Disinfection By-products, and Risk of Bladder Cancer in Spain
- Polymorphisms in NEIL-2, APE-1, CYP2E1 and mdm2 genes are independent predictors of gastric cancer Risk in a Northern Jiangsu Population (China)
- Polymorphisms in the CYP2E1 and GSTM1 genes as possible protection factors for leprosy patients
- Polymorphisms of ADH2, ALDH2 and CYP2E1 in huichol and Mestizo subjects from western México in comparison with other populations of the world
- Polymorphisms of Alcohol Metabolizing Enzymes in Indigenous Mexican Population: Unusual High Frequency of CYP2E1*c2 Allele
- Polymorphisms of CYP1a1, CYP2E1, GSTM1, GSTT1, and TP53 genes in Amerindians
- Polymorphisms of CYP2E1 rs2031920 is not Associated with Risk of Nasopharyngeal Carcinoma in Minangkabau Ethnic Group
- Polymorphisms of drug-metabolizing enzyme CYP2E1 in Chinese Uygur population
- Polymorphisms of GSTP1 and GSTT1 , but not of CYP2A6 , CYP2E1 or GSTM1 , modify the …
- Polymorphisms of NAT2, CYP2E1, GST, and HLA Related to Drug‑Induced Liver Injury in Indonesian Tuberculosis Patients
- Polymorphisms of the CYP1A1 and CYP2E1 genes in head and neck squamous cell carcinoma risk
- Polymorphisms of the CYP1A1, CYP2E1 and XRCC1 genes and cancer risk in a Southern Italian population: a case–control study
- Polymorphisms of the Cytochrome P450 (CYP1A1, CYP2E1) and Microsomal Epoxide Hydrolase (mEPHX) Genes in Cystic Fibrosis and Chronic Respiratory …
- Porcine CYP2A19, CYP2E1 and CYP1A2 forms are responsible for skatole biotransformation in the reconstituted system
- Possible impact of human CYP2E1 polymorphisms on the metabolism of acrylonitrile
- Post-transcriptional regulation of rat CYP2E1 expression: role of CYP2E1 mRNA untranslated regions in control of translational efficiency and message stability
- Potent mutagenicity of some non-planar tri-and tetrachlorinated biphenyls in mammalian cells, human CYP2E1 being a major activating enzyme
- Potentiation of thioacetamide liver injury in diabetic rats is due to induced CYP2E1
- Povezanost polimorfizama gena TP53 i CYP2E1* 5B s nemikrocelularnim karcinomom pluća
- Prediction of The Needs for Benzene Detox with Foods Intake Containing CYP2E1 Enzyme, Sulfation, and Glutathione at Gas Stations Pancoranmas Depok …
- Preliminary effects of alcohol and Curcuma longa upon CYP2E1 and hematotoxicity in benzene-induced mice
- Prenatal antidepressant exposure associated with CYP2E1 DNA methylation change in neonates
- Pretreatment with turmeric modulates the inhibitory influence of cisplatin and paclitaxel on CYP2E1 and CYP3A1/2 in isolated rat hepatic microsomes
- Progress of research on characteristics of cytochrome P-450 CYP2E1 in protein structure and regulation mechanisms
- Promoter function and the role of cytokines in the transcriptional regulation of rabbit CYP2E1 and CYP2E2
- Proteasome inhibition potentiates CYP2E1‐mediated toxicity in HepG2 cells
- Protection against acetaminophen toxicity in CYP1A2 and CYP2E1 double-null mice
- Protective Effect of Curcumin on Acrylamide-Induced Hepatic and Renal Impairment in Rats: Involvement of CYP2E1
- Protective effect of Ornithogalum saundersiae Ait (Liliaceae) against acetaminophen-induced acute liver injury via CYP2E1 and HIF-1α
- Protective Effects of CYP2E1 Inhibitors on Metabolic Syndrome-induced Liver Injury in Guinea Pigs
- Protective effects of diallyl disulfide against acetaminophen-induced nephrotoxicity: a possible role of CYP2E1 and NF-κB
- Protective effects of emodin and chrysophanol isolated from marine fungus Aspergillus sp. on ethanol-induced toxicity in HepG2/CYP2E1 cells
- Protective effects of goldenseal (Hydrastis canadensis L.) on acetaminophen-induced hepatotoxicity through inhibition of CYP2E1 in rats
- Protective effects of loquat (Eriobotrya japonica) leaves against ethanol-induced toxicity in HepG2 cells transfected with CYP2E1
- Protective effects of protein hydrolysate from marine microalgae Navicula incerta on ethanol-induced toxicity in HepG2/CYP2E1 cells
- Protein kinase C signaling as a survival pathway against CYP2E1-derived oxidative stress and toxicity in HepG2 cells
- Proteomics of oxidative stress using inducible CYP2E1 expressing HEPG2 cells and 3T3-L1 adipocytes as model systems
- psychosocial deprivation in early childhood is associated with increased DNA methylation across a region spanning the transcription start site of CYP2E1
- Pulmonary bioactivation of 1, 1-dichloroethylene is associated with CYP2E1 levels in A/J, CD-1, and C57BL/6 mice
- Pulmonary bioactivation of trichloroethylene to chloral hydrate: relative contributions of CYP2E1, CYP2F, and CYP2B1
- Pulmonary CYP2E1 bioactivates 1, 1-dichloroethylene in male and female mice.
- Pulsatile blood alcohol and CYP2E1 induction during chronic alcohol infusions in rats
- Pyrazole induced oxidative liver injury independent of CYP2E1/2A5 induction due to Nrf2 deficiency
- Quantification of CYP2E1 in rat liver by UPLC-MS/MS-based targeted proteomics assay: a novel approach for enzyme activity assessment
- Quantification of Metabolic Reaction Products Catalysed by CYP2E1 Enzyme Activity: Inhibitory Effect of Cytochrome P450 Enzyme CYP2E1 by Salicylic Acid in Rat …
- Quercetin prevents type 1 diabetic liver damage through inhibition of CYP2E1
- Quercetin suppressed CYP2E1-dependent ethanol hepatotoxicity via depleting heme pool and releasing CO
- Radix Rehmanniae, the components of an anti-diabetic foot ulcer herbal formula, on metabolism of model CYP1A2, CYP2C9, CYP2D6, CYP2E1 and CYP3A4 probe …
- Rapid changes in cytochrome P4502E1 (CYP2E1) activity and other P450 isozymes following ethanol withdrawal in rats
- Rat hepatic CYP2E1 is induced by very low nicotine doses: an investigation of induction, time course, dose response, and mechanism
- Rdh13 deficiency weakens carbon tetrachloride-induced liver injury by regulating Spot14 and CYP2E1 expression levels
- Red meat intake, CYP2E1 and PPARγ polymorphisms, and colorectal cancer risk
- Red meat intake, CYP2E1 genetic polymorphisms, and colorectal cancer risk
- Reduced systemic toxicity and preserved vestibular toxicity following co-treatment with nitriles and CYP2E1 inhibitors: a mouse model for hair cell loss
- Reduction of benzene metabolism and toxicity in mice that lack CYP2E1 expression
- Regional and cellular distribution of CYP2E1 in monkey brain and its induction by chronic nicotine
- Regulation of CYP2E1 by ethanol and palmitic acid and CYP4A11 by clofibrate in primary cultures of human hepatocytes
- Regulation of the effects of CYP2E1-induced oxidative stress by JNK signaling
- Regulation of X-Ray Irradiation on the Activity and Expression Levels of CYP1A2 and CYP2E1 in Rats
- Relation of GSTP1 and CYP2E1 polymorphisms with susceptibility to acute leukemia
- Relationship among Qi-deficiency constitution and CYP2E1 gene polymorphisms and anti-tuberculosis drug-induced hepatitis
- Relationship between alcoholism and CYP2E1 C/D polymorphism
- Relationship between alcoholism and CYP2E1 genotypes
- Relationship between CYP2E1 polymorphism and increase of ALT activity during therapy of patients with pulmonary tuberculosis
- Relationship between CYP2E1, GSTT1 genetic polymorphisms and susceptibility to gastric cancer
- Relationship between cytochrome P450 catalytic cycling and stability: fast degradation of ethanol-inducible cytochrome P450 2E1 (CYP2E1) in hepatoma cells is …
- Relationship between gene polymorphism of CYP2E1, CYP1A1, IL-4 and medicamentosa-like dermatitis induced by trichloroethylene
- Relationship between genetic polymorphism of CYP2E1 and ALDH2, and possible susceptibility to alcoholism
- Relationship between genetic polymorphisms of drug-metabolizing enzymes (CYP1A1, CYP1B1, CYP2E1, GSTM1, GSTT1, and NAT2) and p53 gene point mutations …
- Relationship between genetic polymorphisms of drug-metabolizing enzymes (CYP1A1, CYP2E1, GSTM1, and NAT2), drinking habits, histological subtypes, and p53 …
- Relationship between genetic polymorphisms of metabolizing enzymes CYP2E1, GSTM1 and Kazakh’s esophageal squamous cell cancer in Xinjiang
- Relationship between genetic polymorphisms of metabolizing enzymes CYP2E1, GSTM1 and Kazakh’s esophageal squamous cell cancer in Xinjiang, China
- Relationship between mRNA levels quantified by reverse transcription-competitive PCR and metabolic activity of CYP3A4 and CYP2E1 in human liver
- CYP2E1.8.aspx”>Relationship in healthy subjects between CYP2E1 genetic polymorphisms and the 6-hydroxyIation of chlorzoxazone: a putative measure of CYP2E1 activity
- Relationship of ALDH2 rs671 and CYP2E1 rs2031920 with hepatocellular carcinoma susceptibility in East Asians: a meta-analysis
- Relationship of anti-tuberculosis drug-induced liver injury and genetic polymorphisms in CYP2E1 and GST
- Relationship of CYP2E1 RsaⅠ genetic polymorphism and smoking, alcohol drinking habit with risk of rectal cancer
- Relationship of NAT2, CYP2E1 and GSTM1/GSTT1 polymorphisms with mild elevation of liver enzymes in Brazilian individuals under anti-tuberculosis drug …
- RELATIONSHIPS BETWEEN GENETIC POLYMORPHISMS IN CYP2D6 AND CYP2E1 GENES AND LIVER MICROSOMAL DRUG OXIDATION ACTIVITIES
- Relative contributions of CYP1A2 and CYP2E1 to the bioactivation and clearance of 4-aminobiphenyl in adult mice
- Relative roles of CYP2E1 and CYP1A2 in mouse uroporphyria caused by acetone
- Relevance of CYP2E1 to non-alcoholic fatty liver disease
- Removal of glutathione produces apoptosis and necrosis in HepG2 cells overexpressing CYP2E1
- Renal and hepatic accumulation of cadmium and lead in the expression of CYP4F2 and CYP2E1
- Requirement Prediction for Toluene Detox with Foods Intake Rich in CYP2E1 Enzyme and Glycine to Prevent Nerve and Kidney Damage at Shoe Home …
- Research on Association of Genetic Polymorphism of CYP1A1 and CYP2E1, with Susceptibility to Gastric Cancer
- Research on the progress of alcoholic liver disease pathogenesis related to CYP2E1
- Research on the relationship between ALDH2 and CYP2E1 gene polymorphism and alcoholic liver disease in Han people
- Research on the relationship between polymorphism of CYP2E1 and dermatitis medicamentosa-like of trichloroethylene [J]
- Resistance to carbon tetrachloride-induced hepatotoxicity in mice which lack CYP2E1 expression
- Response: Similar effect of quercetin on CYP2E1 and CYP2C9 activities in humans?
- RESULTS OF INTENSIVE PHASE TRETAMENT OF TUBERCULOSIS TREATMENT ACCORDING TO CYP2E1 GENOTYPE
- Resveratrol downregulates CYP2E1 and attenuates chemically induced hepatocarcinogenesis in SD rats
- Resveratrol pretreatment affects CYP2E1 activity of chlorzoxazone in healthy human volunteers
- Rifampicin suppresses hepatic CYP2E1 expression and minimizes DNA injury caused by carbon tetrachloride in perivenular hepatocytes of mice
- Risk assessment: toxicity from chemical exposure resulting from enhanced expression of CYP2E1
- Role and importance of polymorphisms with respect to DNA methylation for the expression of CYP2E1 enzyme
- Role for intestinal CYP2E1 in alcohol-induced circadian gene-mediated intestinal hyperpermeability
- Role of alcohol and genetic polymorphisms of CYP2E1 and ALDH2 in breast cancer development
- Role of brain acetaldehyde in drinking preference: genetic modification of alcohol oxidizing enzymes catalase and CYP2E1 in C57BL/6 mice and their …
- Role of calcium and calcium-activated proteases in CYP2E1-dependent toxicity in HEPG2 cells
- Role of CYP1A2 and CYP2E1 in the pentoxifylline ciprofloxacin drug interaction
- Role of CYP2D6, CYP1A1, CYP2E1, GSTT1, and GSTM1 genes in the susceptibility to acute leukemias
- Role of CYP2E1 (PstI/RsaI) gene polymorphisms on the tacrolimus drug toxicity of kidney transplantations among South Indians
- Role of CYP2E1 activity in endoplasmic reticulum ubiquitination, proteasome association, and the unfolded protein response
- Role of CYP2E1 and NQO1 polymorphisms in oxidative stress derived cancer in Thais with and without dyslipidemia
- Role of CYP2E1 and saturation kinetics in the bioactivation of thioacetamide: Effects of diet restriction and phenobarbital
- Role of CYP2E1 gene polymorphisms association with hepatitis risk in Northeast India
- Role of CYP2E1 Immunoglobulin G4
- Role of CYP2E1 immunoglobulin G4 subclass antibodies and complement in pathogenesis of idiosyncratic drug-induced hepatitis
- Role of CYP2E1 in deramciclane metabolism
- Role of CYP2E1 in diethylnitrosamine-induced hepatocarcinogenesis in vivo
- Role of CYP2E1 in ethanol-induced oxidant stress, fatty liver and hepatotoxicity
- Role of CYP2E1 in Impaired Nitric Oxide Synthase (NOS)‐Dependent Cerebral Vasodilation During Chronic Alcohol Consumption
- Role of CYP2E1 in ketone-stimulated insulin release in pancreatic B-cells
- Role of CYP2E1 in Mitochondrial Dysfunction and Hepatic Injury by Alcohol and Non-Alcoholic Substances
- Role of CYP2E1 in mitochondrial dysfunction and hepatic tissue injury in alcoholic and non-alcoholic diseases
- Role of CYP2E1 in the Epoxidation of Acrylamide to Glycidamide and Formation of DNA and Hemoglobin Adducts
- Role of CYP2E1 in the hepatotoxicity of acetaminophen
- Role of CYP2E1 in the mouse model of MPTP toxicity
- Role of CYP2E1 in the pathogenesis of alcoholic liver disease
- Role of CYP2E1 in the pathogenesis of alcoholic liver disease: modifications by cAMP and ubiquitin-proteasome pathway
- Role of CYP2E1 in thioacetamide-induced mouse hepatotoxicity
- Role of CYP2E1 polymorphisms in breast cancer: a systematic review and meta-analysis
- Role of CYP2E1-mediated metabolism in the acute and vestibular toxicities of nineteen nitriles in the mouse
- Role of CYP3A and CYP2E1 in alcohol-mediated increases in acetaminophen hepatotoxicity: comparison of wild-type and CYP2E1 (–/–) mice
- Role of cytochromes P450 in chemical toxicity and oxidative stress: studies with CYP2E1
- Role of exposure/recovery schedule in micronuclei induction by several promutagens in V79-derived cells expressing human CYP2E1 and SULT1A1
- Role of intracellular calcium and phospholipase A2 in arachidonic acid-induced toxicity in liver cells overexpressing CYP2E1
- Role of mouse CYP2E1 in the O-hydroxylation of p-nitrophenol: comparison of activities in hepatic microsomes from CYP2E1 (-/-) and wild-type mice
- Role of nitric oxide and nuclear factor-κB in the CYP2E1 potentiation of tumor necrosis factor α hepatotoxicity in mice
- Role of NQO1, MPO and CYP2E1 genetic polymorphisms in the susceptibility to childhood acute lymphoblastic leukemia
- Role of P38 MAP kinase in CYP2E1 dependent arachidonic acid toxicity
- Role of p38 MAPK in CYP2E1-dependent arachidonic acid toxicity
- Role of phosphatidylinositol 3-kinase/AKT as a survival pathway against CYP2E1-dependent toxicity
- Role of phospholipase A2 activation and calcium in CYP2E1-dependent toxicity in HepG2 cells
- CYP2E1_and_cyp2d6_genes_in.5.aspx”>Role of polymorphic CYP2E1 and CYP2D6 genes in NNK-induced chromosome aberrations in cultured human lymphocytes
- Role of polymorphic variants of cytochrome P450 genes (CYP1A1, CYP2E1) and microsomal epoxide hydrolase (mEPHX) in pathogenesis of cystic fibrosis and …
- Role of the Genetic Polymorphisms in the 5′‐Flanking Region for Transcriptional Regulation of the Human CYP2E1 Gene
- Role of the Liver-Enriched Transcription Factor HNF-1α in Expression of the CYP2E1 Gene
- Role of the proteasome complex in degradation of human CYP2E1 in transfected HepG2 cells
- Roles of CYP1A1 and CYP2E1 Gene Polymorphisms in Oral Submucous Fibrosis
- Roles of CYP2E1 in 1, 2‐dichloroethane‐induced liver damage in mice
- Roles of CYP2E1 in liver damage induced by 1, 2-dichloroethane
- Romidepsin (FK228) in a Mouse Model of Lipopolysaccharide-Induced Acute Kidney Injury is Associated with Down-Regulation of the CYP2E1 Gene
- RORα switches transcriptional mode of ERRγ that results in transcriptional repression of CYP2E1 under ethanol-exposure
- RsaI but not DraI polymorphism in CYP2E1 gene increases the risk of gastrointestinal cancer in Malaysians: a case–control study
- Ruthenium red protects HepG2 cells overexpressing CYP2E1 against acetaminophen cytotoxicity
- S29. 1 CORRELATION BETWEEN SPERMATOGENESIS DISORDERS AND CYP2E1 MRNA EXPRESSION IN RATS TESTES FOLLOWING CHRONIC …
- S-adenosyl methionine protects ob/ob mice from CYP2E1-mediated liver injury
- S-adenosyl-L-methionine attenuates hepatotoxicity induced by agonistic Jo2 Fas antibody following CYP2E1 induction in mice
- Safrole-DNA adducts in human peripheral blood—an association with areca quid chewing and CYP2E1 polymorphisms
- Salidroside protects mice against CCl4-induced acute liver injury via down-regulating CYP2E1 expression and inhibiting NLRP3 inflammasome activation
- Salvia fruticosa Modulates mRNA Expressions and Activity Levels of Xenobiotic Metabolizing CYP1A2, CYP2E1, NQO1, GPx, and GST Enzymes in Human …
- Scrophularia ningpoensis, Asparagus cochinchinensis and Ophiopogon japonicas on contents of CYP450 and activities of CYP3A, CYP2E1 and CYP1A2 in rat
- Selective time-and NADPH-dependent inhibition of human CYP2E1 by clomethiazole
- Serum autoantibodies against cytochrome P450 2E1 (CYP2E1) predict severity of liver graft hepatitis C recurrence
- Serum autoantibodies against cytochrome P450 2E1 (CYP2E1) predict severity of necroinflammation of recurrent hepatitis C
- Serum deprivation-induced HepG2 cell death is potentiated by CYP2E1
- Sex steroid hormones regulate constitutive expression of CYP2E1 in female mouse liver
- Shanxi aged vinegar prevents alcoholic liver injury by inhibiting CYP2E1 and NADPH oxidase activities
- Short-term treatment with alcohols causes hepatic steatosis and enhances acetaminophen hepatotoxicity in CYP2E1 (-/-) mice
- Significance of genetic polymorphisms at multiple loci of CYP2E1 in the risk of development of childhood acute lymphoblastic leukemia
- Significant genotype difference in the CYP2E1 PstI polymorphism of indigenous groups in Sabah, Malaysia with Asian and non-Asian populations
- Silver Nanoparticle-Doped Poly (8-Anilino-1-Naphthalene Sulphonic Acid)/CYP2E1 Nanobiosensor for Isoniazid-A First Line Anti-Tuberculosis Drug
- Similar effect of quercetin on CYP2E1 and CYP2C9 activities in humans?
- Similarity Check: Genotype Polymorphisms Of Nat2 And CYP2E1 Genes Associated With Drug Induced Liver Injury (Dili) In Indonesian Tuberculosis Patients
- Simultaneous phenotyping of CYP2E1 and CYP3A using oral chlorzoxazone and midazolam microdoses
- Single-nucleotide polymorphisms in cytochrome P450 2E1 (CYP2E1) 3′-untranslated region affect the regulation of CYP2E1 by miR-570
- Sodium salicylate increases CYP2E1 levels and enhances arachidonic acid toxicity in HepG2 cells and cultured rat hepatocytes
- Spectrophotometric Analysis of Human CYP2E1-Catalyzed p-Nitrophenol Hydroxylation
- Spin trapping agents (Tempol and POBN) protect HepG2 cells overexpressing CYP2E1 against arachidonic acid toxicity
- St. John’s wort extract induces CYP3A and CYP2E1 in the Swiss Webster mouse
- Stable expression of human CYP2E1 in Chinese hamster cells: high sensitivity to N, N-dimethylnitrosamine in cytotoxicity testing
- Striking LD50 variation associated with fluctuations of CYP2E1-positive cells in hepatic lobule during chronic CCl4 exposure in mice
- Structure of pyrazole derivatives impact their affinity, stoichiometry, and cooperative interactions for CYP2E1 complexes
- Structure-functional characterization of cytochrome P4502E1 (CYP2E1)
- Structure-toxicity relationship study of para-halogenated styrene analogues in CYP2E1 transgenic cells
- CYP2E1.7.aspx”>Studies on interindividual variations of CYP2E1 using chlorzoxazone as an in vivo probe
- Studies on Pharmacokinetic Interaction Among CYP1A2, CYP2E1 and CYP3A4 Probes in Rats [J]
- Study of CYP2E1 gene RsaI/PstI polymorphisms in patients with gastric cancer in north of Iran
- Study of genetic polymorphisms of CYP2E1 and GSTM1
- Study of polymorphisms in the CYP2E1 gene in patients with alcoholic pancreatitis
- Study of the fragmentation mechanism of protonated 6-hydroxychlorzoxazone: application in simultaneous analysis of CYP2E1 activity with major human cytochrome …
- STUDY ON AA METABOLISM IN RAT LIVER AND THE EXPRESSION OF CYP2E1
- Study on Chinese medicine constitution and its relation with CYP2E1 gene polymorphisms of anti‐tuberculosis drug‐induced hepatitis
- Study on inhibitory effect of water extract of Polygonum multiflorum on CYP1A2 and CYP2E1 enzymatic activities and mRNA expressions in rat liver
- Study on the association between CYP2E1 enzymes and susceptibility of alcoholic liver disease
- Study on the association between genetic polymorphism of CYP2E1, GSTM1 and susceptibility of lung cancer
- Study the effect of Baijie Capsule on cytochrome P450 isozymes CYP2C19, CYP2E1 by cocktail probe drugs
- Study the effect of cytochrome p450 isozymes cyp1A2, cyp3A4, CYP2E1 following administration of Zhenqi Fuzheng Capsules by cocktail probe drugs [J]
- Subcellular localization of rat CYP2E1 impacts metabolic efficiency toward common substrates
- Sulforaphane induces Nrf2 and protects against CYP2E1-dependent binge alcohol-induced liver steatosis
- Suppression of cytochrome P450 2E1 promoter activity by interferon-γ and loss of response due to the-71G> T nucleotide polymorphism of the CYP2E1* 7B allele
- Sus scrofa mRNA for cytochrome p450 2E1 (CYP2E1 gene)
- Sus scrofa partial CYP2E1 gene for cytochrome p450 2E1, exon 9 and partial CDS
- Susceptibility to the acute toxicity of acrylonitrile in streptozotocin-induced diabetic rats: protective effect of phenethyl isothiocyanate, a phytochemical CYP2E1 …
- Synergistic association of PTGS2 and CYP2E1 genetic polymorphisms with lung cancer risk in northeastern Chinese
- Synergistic toxic interactions between CYP2E1, LPS/TNFα, and JNK/p38 MAP kinase and their implications in alcohol-induced liver injury
- Synergistic toxicity of iron and arachidonic acid in HepG2 cells overexpressing CYP2E1
- Synonymous mutation rs2515641 affects CYP2E1 mRNA and protein expression and susceptibility to drug-induced liver injury
- Tandem Repeat Polymorphism of the CYP2E1 Gene: An Association Study With Esophageal Cancer and Lung Cancer
- Targeted CYP2E1 quantification and its correlation to currently acceptable clinical biochemical indices
- Targeted delivery of CYP2E1 recombinant adenovirus to malignant melanoma by bone marrow-derived mesenchymal stem cells as vehicles
- Taurine protects acetaminophen-induced oxidative damage in mice kidney through APAP urinary excretion and CYP2E1 inactivation
- Tetra primer ARMS PCR optimization to detect single nucleotide polymorphisms of the CYP2E1 gene
- The Action of Cytochrome b5 on CYP2E1 and CYP2C19 Activities Requires Anionic Residues D58 and D65
- The activity, protein, and mRNA expression of CYP2E1 and CYP3A1 in rats after exposure to acute and chronic high altitude hypoxia
- The ADH3* 2 and CYP2E1 c2 alleles increase the risk of alcoholism in Mexican American men
- The alcohol-inducible form of cytochrome P450 (CYP2E1): role in toxicology and regulation of expression
- The association between CYP2E1 polymorphisms and hepatotoxicity due to anti-tuberculosis drugs: a meta-analysis
- The Association of CYP2E1 Polymorphism and Environmental Factor in Nasopharyngeal Carcinoma Patients
- The Changes in the Analgesic Effect of Probe Drug Chlorzoxazone Metabolized by CYP2E1 on Alcoholic Liver Injury in Rats
- The CYP2E1 inhibitor DDC up-regulates MMP-1 expression in hepatic stellate cells via an ERK1/2-and Akt-dependent mechanism
- The CYP2E1-humanized transgenic mouse: role of CYP2E1 in acetaminophen hepatotoxicity
- The cytochrome P-450 isoenzyme CYP2E1 in the biological processing of industrial chemicals: consequences for occupational and environmental medicine
- The difference of metabolism activity of CYP2E1 between in immune liver damage rats and in alcohol-mediated hepatic injury rats
- The effect of changes in CYP2E1 activity in the liver on toxicity and carcinogenicity of diethylnitrosamine in mice
- The effect of CYP2E1-dependent oxidant stress on activity of proteasomes in HepG2 cells
- The effect of endotoxin on hepatocyte nuclear factor 1 nuclear protein binding: potential implications on CYP2E1 expression in the rat
- The effect of ethanol and nitric oxide on the N-nitrosodimethylamine formation in HepG2 cells overexpressing CYP2E1
- THE EFFECT OF ETHANOL ON COUMARIN METABOLISM AND CYTOTOXICITY IN TRANSFECTED CULTURES OF HEPG2 CELLS WITH CYP2E1 EXPRESSION.
- The effect of ethanol-induced CYP2E1 on proteasome activity: the role of 4-hydroxynonenal
- The Effect of Huangqi on CYP2E1 Activity of Diabetic Rats
- The effect of isoniazid containing regimen on CYP2E1 during antituberculosis therapy.
- The effect of isoniazid on CYP2E1-and CYP4A-mediated hydroxylation of arachidonic acid in the rat liver and kidney
- The effect of lycopene on the total cytochrome P450, CYP1A2 and CYP2E1
- The effect of organic solvents and CYP1A1, CYP2E1, GSTM1 polymorphisms on the development of acute lymphoblastic leukemia in Quebec children
- The effect of quercetin on the pharmacokinetics of chlorzoxazone, a CYP2E1 substrate, in healthy subjects
- The effect of SNPs in the promoter on expression of CYP2E1 gene and boar taint
- The effects of alcohol and diallyl sulphide on CYP2E1 activity in humans: a phenotyping study using chlorzoxazone
- The effects of bovine serum albumin on kinetic characterization of human liver microsomal CYP2C19 and CYP2E1 activities
- The Effects of CYP2E1 on Hepatic Gene Expression in 129/Sv-CYP2E1^ tm1Gonz/J and 129S1/SvImJ Mice Exposed to Hydrazine
- The effects of non-esterified fatty acids and β-hydroxybutyrate on the hepatic CYP2E1 in cows with clinical ketosis
- The Effects of Poly IC and Human Interferon ɑ on Rat Hepatic Cyp4a1 and CYP2E1.
- The effects of the ALDH2* 1/2, CYP2E1 c1/c2 and C/D genotypes on blood ethanol elimination and the human serotonin receptor (HTR2) gene Msp1 polymorphism in …
- THE EFFECTS OF THE ALDH2*1/2, CYP2E1 C1/C2 AND C/D GENOTYPES ON BLOOD ETHANOL ELIMINATION
- The effects of toluene on the total CYP450 content and on levels of CYP2E1 and 2B6 Isoforms in the rat liver
- The essential role of CYP2E1 in metabolism and hepatotoxicity of N,N-dimethylformamide using a novel CYP2E1 knockout mouse model and a population study
- The ethanol elimination pharmacokinetics–the effects of genotypes of ALDH2 and CYP2E1 on the ethanol metabolism
- The FANCG Fanconi anemia protein interacts with CYP2E1: possible role in protection against oxidative DNA damage
- The genetic profiles of CYP1A1, CYP1A2 and CYP2E1 enzymes as susceptibility factor in xenobiotic toxicity in Turkish population
- The genetic regulation of liver microsomal CYP2E1 activity among strains of the viviparous fish Poeciliopsis
- The genotype of CYP2E1 and liver-derived serum enzymes
- The GST T1 and CYP2E1 genotypes are possible factors causing vinyl chloride induced abnormal liver function
- The human CYP2E1 gene and lung cancer: DraI and RsaI restriction fragment length polymorphisms in a Finish study population
- The impact of CYP1A2 and CYP2E1 genes polymorphism on theophylline response
- The impact of CYP2E1 genetic variability on risk assessment of VOC mixtures
- The impact of CYP2E1 on the development of alcoholic liver disease as studied in a transgenic mouse model
- The impact of psychogenic stressors on oxidative stress markers and patterns of CYP2E1 expression in mice liver
- The importance of CYP2E1 in the pathogenesis of alcoholic liver disease and drug toxicity and the role of the proteasome
- The inactivation of human CYP2E1 by phenethyl isothiocyanate, a naturally occurring chemopreventive agent, and its oxidative bioactivation
- The induction of the human hepatic CYP2E1 gene by interleukin 4 is transcriptional and regulated by protein kinase C
- The influence of genetic polymorphism of CYP2E1 on the development of alcohol liver cirrhosis
- The influence of Jiuganning decoction on the content of CYP2E1 and cytokine IL-6, TNF in rats models of alcoholic hepatic injury
- The Inhibitory Effect of the Derris scandens Extract on Cytochrome P450 2E1 (CYP2E1)-associated Aniline-4-Hydroxylase in vitro
- The LRP6 functional mutation rs2302685 contributes to individual susceptibility to alcoholic liver injury related to the Wnt/β-catenin-TCF1-CYP2E1 signaling pathway
- The Meta Isomer of Acetaminophen Is A Time Dependent Inhibitor of Human CYP2E1
- The mode of cisplatin-induced cell death in CYP2E1-overexpressing HepG2 cells: modulation by ERK, ROS, glutathione, and thioredoxin
- The modeling of interactions of the CYP2E1 isoform of human cytochrome P450 with substrates
- The modifying effect of CYP2E1, GST, and mEH genotypes on the formation of hemoglobin adducts of acrylamide and glycidamide in workers exposed to acrylamide
- The molecular mechanism regulating 24‐hour rhythm of CYP2E1 expression in the mouse liver
- The NH2-terminal region of rabbit CYP2E1 is not essential for interaction with NADPH-cytochrome P450 reductase
- The Physiological Mechanism of Improved Formaldehyde Resistance in Petunia hybrida Harboring a Mammalian CYP2E1 Gene
- The Physiological Mechanism of Petunia hybrida Harboring Mammalian CYP2E1 Gene Improving Resistance to Formaldehyde
- The pig CYP2E1 promoter is activated by COUP-TF1 and HNF-1 and is inhibited by androstenone
- The polymorphism of CYP2E1 Rsa I/Pst I gene and susceptibility to respiratory system cancer: a systematic review and meta-analysis of 34 studies
- The polymorphism rs2480258 within CYP2E1 is associated with different rates of acrylamide metabolism in vivo in humans
- The possible mechanisms of CYP2E1 interactions with HSP90 and the influence of ethanol on them
- The regulation of CYP2E1 gene expression and its role in breast cancer
- CYP2E1-genotype-and-ab”>The relationship between the GST T1, GST M1, CYP2E1 genotype and abnormal liver function in PVC workers
- The research on the relationship between CD44, CYP2E1 genetic polymorphisms and esophageal cancer
- The role of CYP2A and CYP2E1 in the metabolism of 3-methylindole in primary cultured porcine hepatocytes
- The role of CYP2A6 and CYP2E1 in the metabolism of 3-methylindole in porcine hepatocytes.
- The role of CYP2E1 and 2B1 in metabolic activation of benzene derivatives
- The role of CYP2E1 and CYP4A in the development of non-alcoholic steatohepatitis
- The Role of CYP2E1 IgG4 Subclass Autoantibodies in the Development of Anesthetic Sensitization
- The role of CYP2E1 in alcohol metabolism and sensitivity in the central nervous system
- The Role of CYP2E1 in the Drug Metabolism or Bioactivation in the Brain
- The role of CYP2E1 in the protection of garlic oil’s from n-hexane-induced neurotoxicity
- THE ROLE OF CYP2E1 POLYMORPHISM IN THE ACTIVATION OF PROCARCINOGEN METABOLISM OF NASOPHARYNGEAL CARCINOMA
- The role of inflammatory and oxidative stress, CYP2E1 and bile acid disturbance in rat liver injury induced by isoniazid and lipopolysaccharide co-treatment
- The role of phosphatidylinositol 3-kinase, Src kinase, and protein kinase A signaling pathways in insulin and glucagon regulation of CYP2E1 expression
- The RsaI polymorphism of CYP2E1 and susceptibility to alcoholic liver disease in Caucasians: effect on age of presentation and dependence on alcohol …
- The WNT/β-catenin pathway is a transcriptional regulator of CYP2E1, CYP1A2, and aryl hydrocarbon receptor gene expression in primary human hepatocytes
- Theoretical study of the mechanism of acetaldehyde hydroxylation by compound I of CYP2E1
- Therapeutic hypothermia-induced pharmacokinetic alterations on CYP2E1 chlorzoxazone-mediated metabolism in a cardiac arrest rat model
- Therapeutic potential of CYP2E1 inhibitor combined N-acetyl-cysteine in acute acrylonitrile intoxication in rats
- Tightly regulated and inducible expression of rabbit CYP2E1 using a tetracycline-controlled expression system
- Tissue-specific expression and methylation of the human CYP2E1 gene
- Toward a systems approach to cytochrome P450 ensemble: interactions of CYP2E1 with other P450 species and their impact on CYP1A2
- Trade herbal products and induction of CYP2C19 and CYP2E1 in cultured human hepatocytes
- Transcription factor Nrf2 protects HepG2 cells against CYP2E1 plus arachidonic acid-dependent toxicity
- Transcriptional activity of the tandem repeat polymorphism in the 5′‐flanking region of the human CYP2E1 gene
- CYP2E1&ots=AGYoKkGapZ&sig=lKqFX7Bx9cBbiySnxK-Kg_pu_Gk”>Transcriptional and posttranscriptional regulation of CYP2E1, an N-nitrosodimethylamine demethylase
- Transcriptional control of CYP2E1 in the perivenous liver region and during starvation
- Transcriptional control of the rat hepatic CYP2E1 gene.
- Transfected HepG2 cells for evaluation of catechin effects on alcohol-induced CYP2E1 cytotoxicity
- Transgenic alfalfa plants co-expressing glutathione S-transferase (GST) and human CYP2E1 show enhanced resistance to mixed contaminates of heavy metals and …
- Transgenic plant regeneration of tobacco (Nicotiana tabacum) haboring mammalian CYP2E1 gene
- Transgenic plants of Petunia hybrida harboring the CYP2E1 gene efficiently remove benzene and toluene pollutants and improve resistance to formaldehyde
- Translational activation of ethanol-inducible cytochrome P450 (CYP2E1) by isoniazid
- Trifluoroacetylated adducts in spermatozoa, testes, liver and plasma and CYP2E1 induction in rats after subchronic inhalatory exposure to halothane
- Trimethadione metabolism by human liver cytochrome P450: evidence for the involvement of CYP2E1
- Trimethadione N-demethylation by rat liver CYP2E1 in vitro.
- TRPV4 activation of endothelial nitric oxide synthase resists nonalcoholic fatty liver disease by blocking CYP2E1-mediated redox toxicity
- TRPV4 attenuates M1 polarization and subsequent NASH progression by stalling CYP2E1-mediated redox toxicity via eNOS.
- TRPV4 Modulates CYP2E1 Function in Nonalcoholic Steatohepatitis Progression
- Ultrasensitive quantification of the CYP2E1 probe chlorzoxazone and its main metabolite 6-hydroxychlorzoxazone in human plasma using ultra performance liquid …
- Undernutrition during hyperoxic exposure induces CYP2E1 in rat liver
- Unraveling CYP2E1 haplotypes in alcoholics from Central Brazil: A comparative study with 1000 genomes population
- UPREGULATING OF CYP2E1 IN ETHANOL-FED MICE WITH TRANSGENIC OVEREXPRESSION OF CTRP3
- Upregulation of CYP2E1 and cyp3a activities in histamine-deficient histidine decarboxylase gene targeted mice
- Upregulation of CYP2E1 expression causes oxidative damage induced by 2-chloroethanol in primary cultured rat astrocytes
- Urinary Biomarker of Prenatal Exposure to Disinfection Byproducts, Maternal Genetic Polymorphisms in CYP2E1 and GSTZ1, and Birth Outcomes
- Urinary excretion of 6‐hydroxychlorzoxazone as an index of CYP2E1 activity
- Use of CYP2E1‐transfected human liver cell lines in elucidating the actions of ethanol
- Use of Cytochrome P450 2E1 (CYP2E1) Knockout Transgenic Mouse Model to Study the Role of CYP2E1 in Carbon Tetrachloride-and Alcohol-mediated …
- Use of molecular simulation for mapping conformational CYP2E1 epitopes
- Use of the CYP2E1 genotype and phenotype for the biological monitoring of occupational exposure to styrene
- Validation of 4-nitrophenol as an in vitro substrate probe for human liver CYP2E1 using cDNA expression and microsomal kinetic techniques
- Validation of the (ω-l)-hydroxylation of lauric acid as an in vitro substrate probe for human liver CYP2E1
- Value of polymorphisms and DNA methylation for the expression of CYP2E1 enzyme: implications in pharmacogenomics
- Variable Number of Tandem Repeats (VNTR) gene polymorphism of CYP2E1 in patients with pancreatic adenocarcinoma
- Variation in induction of human placental CYP2E1: possible role in susceptibility to fetal alcohol syndrome?
- Variations in expression of CYP2E1 and COUP-TF1 proteins between Large White and Duroc cross-breeds
- Voglibose potentiates the hepatotoxicity of carbon tetrachloride and acetaminophen by inducing CYP2E1 in rats
- Watercress has no importance for the elimination of ethanol by CYP2E1 inhibition
- XRCC1 and CYP2E1 polymorphisms as susceptibility factors of plasma mutant p53 protein and anti-p53 antibody expression in vinyl chloride monomer-exposed …
- XRCC1, CYP2E1 and ALDH2 genetic polymorphisms and sister chromatid exchange frequency alterations amongst vinyl chloride monomer-exposed polyvinyl …
- Zebrafish have an ethanol-inducible hepatic 4-nitrophenol hydroxylase that is not CYP2E1-like
- ZSCAN25 and CYP2E1 polymorphisms is risk factors for ischemic stroke in a Chinese Han population: a case control study
- π–π Stacking mediated drug–drug interactions in human CYP2E1
- Identification of cytochrome CYP2E1 as critical mediator of synergistic effects of alcohol and cellular lipid accumulation in hepatocytes in vitro
- Danshen (Salvia miltiorrhiza) water extract inhibits paracetamol-induced toxicity in primary rat hepatocytes via reducing CYP2E1 activity and oxidative stress
- Cytochrome P-450 CYP2E1 knockout mice are protected against high-fat diet-induced obesity and insulin resistance
- … patients treated for TB in Xinjiang Uyghur autonomous region, China, and its association with hepatic enzyme polymorphisms nat2, CYP2E1, gstm1 and gstt1
- In vitro inhibition of human CYP2E1 and CYP3A by quercetin and myricetin in hepatic microsomes is not gender dependent
- Cytochrome P450 2E1 (CYP2E1) positively regulates lipid catabolism and induces browning in 3T3-L1 white adipocytes
- Selective time-and NADPH-dependent inhibition of human CYP2E1 by clomethiazole
- Expression and activities of hepatic cytochrome P450 (CYP1A, CYP2A and CYP2E1) in entire and castrated male pigs
- Quercetin suppressed CYP2E1-dependent ethanol hepatotoxicity via depleting heme pool and releasing CO
- CYP2E1-dependent and leptin-mediated hepatic CD57 expression on CD8+ T cells aid progression of environment-linked nonalcoholic steatohepatitis
- Effects of unprocessed versus vinegar-processed Schisandra chinensis on the activity and mRNA expression of CYP1A2, CYP2E1 and CYP3A4 enzymes in rats
- … in rats induced by aqueous extract of Polygoni Multiflori Radix, root of Polygonum multiflorum related to the activity inhibition of CYP1A2 or CYP2E1
- Association between the CYP2E1 polymorphisms and lung cancer risk: a meta-analysis
- Additive effects of mitochondrion-targeted cytochrome CYP2E1 and alcohol toxicity on cytochrome c oxidase function and stability of respirosome complexes
- Polymorphisms in GSTM1, CYP1A1, CYP2E1, and CYP2D6 are associated with susceptibility and chemotherapy response in non-small-cell lung cancer patients
- Role of CYP2E1 polymorphisms in breast cancer: a systematic review and meta-analysis
- TRPV4 activation of endothelial nitric oxide synthase resists nonalcoholic fatty liver disease by blocking CYP2E1-mediated redox toxicity
- Tetra primer ARMS PCR optimization to detect single nucleotide polymorphisms of the CYP2E1 gene
- The inactivation of human CYP2E1 by phenethyl isothiocyanate, a naturally occurring chemopreventive agent, and its oxidative bioactivation
- Genetic variants of ALDH2-rs671 and CYP2E1-rs2031920 contributed to risk of hepatocellular carcinoma susceptibility in a Chinese population
- Genetic polymorphisms of CYP2E1 and DNA repair genes HOGG1 and XRCC1: association with hepatitis B related advanced liver disease and cancer
- Cytochrome P450 CYP2E1 suppression ameliorates cerebral ischemia reperfusion injury
- Association of genetic polymorphisms of CYP2E1, NAT2, GST and SLCO1B1 with the risk of anti-tuberculosis drug-induced liver injury: a systematic review …
- Genetic polymorphisms of CYP2E1 and GSTM1 loci and susceptibility to anti-tuberculosis drug-induced hepatotoxicity
- Nicotinamide N-oxidation by CYP2E1 in human liver microsomes
- CYP1A1 and CYP2E1 genotypes and risk of esophageal squamous cell carcinoma in a high-incidence region, Kashmir
- Potent mutagenicity of some non-planar tri-and tetrachlorinated biphenyls in mammalian cells, human CYP2E1 being a major activating enzyme
- Chronic acrylamide exposure in male mice results in elevated DNA damage in the germline and heritable induction of CYP2E1 in the testes
- Shanxi aged vinegar prevents alcoholic liver injury by inhibiting CYP2E1 and NADPH oxidase activities
- Inhibition of CYP2E1 leads to decreased advanced glycated end product formation in high glucose treated ADH and CYP2E1 over-expressing VL-17A cells
- The possible mechanisms of CYP2E1 interactions with HSP90 and the influence of ethanol on them
- Genetic polymorphisms of CYP2E1, GST, and NAT2 enzymes are not associated with risk of breast cancer in a sample of Lebanese women
- Urinary biomarker of prenatal exposure to disinfection byproducts, maternal genetic polymorphisms in CYP2E1 and GSTZ1, and birth outcomes
- CYP2E1 phenotype in Mexican workers occupationally exposed to low levels of toluene
- Effects of alcohol-induced increase in CYP2E1 content in human liver microsomes on the activity and cooperativity of CYP3A4
- Genetic polymorphism of cytochrome P450 (CYP) 1A1, CYP1A2, and CYP2E1 genes modulate susceptibility to gastric cancer in patients with Helicobacter …
- Cooperative effects for CYP2E1 differ between styrene and its metabolites
- Polymorphisms of the CYP1A1 and CYP2E1 genes in head and neck squamous cell carcinoma risk
- Effectiveness of antioxidant treatments on cytochrome P450 2E1 (CYP2E1) activity after alcohol exposure in humans and in vitro models: A systematic review
- Alteration in the expression of cytochrome P450s (CYP1A1, CYP2E1, and CYP3A11) in the liver of mouse induced by microcystin-LR
- Exploration of inhibition potential of isoniazid and its metabolites towards CYP2E1 in human liver microsomes through LC-MS/MS analysis
- Application of an updated physiologically based pharmacokinetic model for chloroform to evaluate CYP2E1-mediated renal toxicity in rats and mice
- Genetic polymorphisms of drug‐metabolizing phase I enzymes CYP2E1, CYP2A6 and CYP3A5 in South Indian population
- HBx inhibits CYP2E1 gene expression via downregulating HNF4α in human hepatoma cells
- Associations between CYP1A1 and CYP2E1 polymorphisms and susceptibility to esophageal cancer in Chaoshan and Taihang areas of China
- Featured structure-activity relationships for some tri-and tetrachlorobiphenyls in human CYP2E1-activated mutagenicity—impact of the extent of ortho-chlorination
- Polymorphisms of NAT2, CYP2E1, GST, and HLA related to drug-induced liver injury in indonesian tuberculosis patients
- CHIP−/−-mouse liver: adiponectin-AMPK-FOXO-activation overrides CYP2E1-elicited JNK1-activation, delaying onset of NASH: therapeutic implications
- Protective effect of curcumin on acrylamide-induced hepatic and renal impairment in rats: Involvement of CYP2E1
- Associations of CYP2E1 rs2031920 and rs3813867 polymorphisms with colorectal cancer risk: a systemic review and meta-analysis
- Altered vulnerability to asthma at various levels of ambient Benzo [a] Pyrene by CTLA4, STAT4 and CYP2E1 polymorphisms
- CYP2E1 Rsa I/Pst I polymorphism contributes to oral cancer susceptibility: a meta-analysis
- Genetic polymorphisms of SLCO1B1, CYP2E1 and UGT1A1 and susceptibility to anti-tuberculosis drug-induced hepatotoxicity: a Chinese population-based …
- CYP2E1 and NQO1 genotypes and bladder cancer risk in a Lebanese population
- Triptolide regulates oxidative stress and inflammation leading to hepatotoxicity via inducing CYP2E1
- Resveratrol downregulates CYP2E1 and attenuates chemically induced hepatocarcinogenesis in SD rats
- Development of an IgY antibody-based immunoassay for the screening of the CYP2E1 inhibitor/enhancer from herbal medicines
- Inhibition of CYP2E1 leads to decreased malondialdehyde–acetaldehyde adduct formation in VL-17A cells under chronic alcohol exposure
- Association between polymorphism of GSTP1, GSTT1, GSTM1 and CYP2E1 genes and susceptibility to benzene-induced hematotoxicity
- … bias and subsequent nonalcoholic steatohepatitis progression is attenuated by nitric oxide donor DETA NONOate via inhibition of CYP2E1-induced oxidative stress in …
- Human placental lactogen induces CYP2E1 expression via PI 3-kinase pathway in female human hepatocytes
- Regulation of X-Ray Irradiation on the Activity and Expression Levels of CYP1A2 and CYP2E1 in Rats
- Nanoformulated SOD1 ameliorates the combined NASH and alcohol-associated liver disease partly via regulating CYP2E1 expression in adipose tissue and liver
- The essential role of CYP2E1 in metabolism and hepatotoxicity of N, N-dimethylformamide using a novel CYP2E1 knockout mouse model and a population study
- Genotoxicity of 1‐methylpyrene and 1‐hydroxymethylpyrene in chinese hamster V79‐derived cells expressing both human CYP2E1 and SULT1A1
- Simultaneous phenotyping of CYP2E1 and CYP3A using oral chlorzoxazone and midazolam microdoses
- Genetic Polymorphisms in CYP2E1: Association with Schizophrenia Susceptibility and Risperidone Response in the Chinese Han Population
- Human CYP2E1-activated mutagenicity of dioxin-like PCBs 105 and 118—Experimental data consistent with molecular docking results
- CYP2E1-mediated oxidative stress regulates HO-1 and GST expression in maneb-and paraquat-treated rat polymorphonuclear leukocytes
- Aidi injection altered the activity of CYP2D4, CYP1A2, CYP2C19, CYP3A2, CYP2E1 and CYP2C11 in normal and diethylnitrosamine-induced hepatocellular …
- Investigation of the inhibition of eight major human cytochrome P450 isozymes by a probe substrate cocktail in vitro with emphasis on CYP2E1
- Synergistic toxic interactions between CYP2E1, LPS/TNFα, and JNK/p38 MAP kinase and their implications in alcohol-induced liver injury
- Inhibitory effects of cytochrome P450 enzymes CYP1A2, CYP2A6, CYP2E1 and CYP3A4 by extracts and alkaloids of Gelsemium elegans roots
- Concentration-dependent inhibitory effect of baicalin on the plasma protein binding and metabolism of chlorzoxazone, a CYP2E1 probe substrate, in rats in …
- The activity, protein, and mRNA expression of CYP2E1 and CYP3A1 in rats after exposure to acute and chronic high altitude hypoxia
- Synergistic association of PTGS2 and CYP2E1 genetic polymorphisms with lung cancer risk in northeastern Chinese
- Structural basis for cooperative binding of azoles to CYP2E1 as interpreted through guided molecular dynamics simulations
- CYP2E1 plays a suppressive role in hepatocellular carcinoma by regulating Wnt/Dvl2/β-catenin signaling
- Genetic interaction between NAT2, GSTM1, GSTT1, CYP2E1, and environmental factors is associated with adverse reactions to anti-tuberculosis drugs
- Polymorphisms of drug-metabolizing enzyme CYP2E1 in Chinese Uygur population
- Organosulfur compounds in fermented garlic extracts and the effects on alcohol induced cytotoxicity in CYP2E1-transfected HepG2 cells
- TA allele of rs2070673 in the CYP2E1 gene is associated with lobular inflammation and nonalcoholic steatohepatitis in patients with biopsy‐proven nonalcoholic fatty …
- Metallothionein protects against isoniazid-induced liver injury through the inhibition of CYP2E1-dependent oxidative and nitrosative impairment in mice
- The impact of psychogenic stressors on oxidative stress markers and patterns of CYP2E1 expression in mice liver
- A single nucleotide polymorphism in the CYP2E1 gene promoter affects skatole content in backfat of boars of two commercial Duroc-sired crossbred populations
- Salvia fruticosa Modulates mRNA Expressions and Activity Levels of Xenobiotic Metabolizing CYP1A2, CYP2E1, NQO1, GPx, and GST Enzymes in Human …
- Ethanol self-administration and nicotine treatment induce brain levels of CYP2B6 and CYP2E1 in African green monkeys
- Inhibition of CYP2E1 attenuates myocardial dysfunction in a murine model of insulin resistance through NLRP3-mediated regulation of mitophagy
- CYP2E1 RsaI/PstI polymorphism and gastric cancer susceptibility: meta-analyses based on 24 case-control studies
- CYP2E1-catalyzed alcohol metabolism: Role of oxidant generation in interferon signaling, antigen presentation and autophagy
- Role of exposure/recovery schedule in micronuclei induction by several promutagens in V79-derived cells expressing human CYP2E1 and SULT1A1
- Protective effect of Schisandra chinensis total lignans on acute alcoholic-induced liver injury related to inhibiting CYP2E1 activation and activating the Nrf2/ARE …
- Effect of Acrylamide Treatment on CYP2E1 Expression and Redox Status in Rat Hepatocytes
- Association between CYP2E1 polymorphisms and risk of differentiated thyroid carcinoma
- … Radix Rehmanniae, the components of an anti-diabetic foot ulcer herbal formula, on metabolism of model CYP1A2, CYP2C9, CYP2D6, CYP2E1 and CYP3A4 probe …
- Association of CYP2E1, STK15 and XRCC1 polymorphisms with risk of breast cancer in Malaysian women
- Alcohol suppresses cardiovascular diurnal variations in male normotensive rats: Role of reduced PER2 expression and CYP2E1 hyperactivity in the heart
- Reduced systemic toxicity and preserved vestibular toxicity following co-treatment with nitriles and CYP2E1 inhibitors: a mouse model for hair cell loss
- CYP2E1 impairs GLUT4 gene expression and function: NRF2 as a possible mediator
- Cooperativity in CYP2E1 metabolism of acetaminophen and styrene mixtures
- Relationship of NAT2, CYP2E1 and GSTM1/GSTT1 polymorphisms with mild elevation of liver enzymes in Brazilian individuals under anti-tuberculosis drug …
- CYP1A1, CYP2E1 and EPHX1 polymorphisms in sporadic colorectal neoplasms
- The impact of CYP1A2 and CYP2E1 genes polymorphism on theophylline response
- Gene copy number variation analysis reveals dosage-insensitive expression of CYP2E1
- The modifying effect of CYP2E1, GST, and mEH genotypes on the formation of hemoglobin adducts of acrylamide and glycidamide in workers exposed to acrylamide
- Adverse outcome pathway on CYP2E1 activation leading to liver cancer
- Increased DNA damage is not associated to polymorphisms in OGGI DNA repair gene, CYP2E1 detoxification gene, and biochemical and hematological findings in …
- CYP2E1 and miRNA‐378a‐3p contribute to acetaminophen‐or tripterygium glycosides‐induced hepatotoxicity
- Dietary aflatoxin B1 intake, genetic polymorphisms of CYP1A2, CYP2E1, EPHX1, GSTM1, and GSTT1, and gastric cancer risk in Korean
- Structure of pyrazole derivatives impact their affinity, stoichiometry, and cooperative interactions for CYP2E1 complexes
- Allyl methyl trisulfide protected against acetaminophen (paracetamol)-induced hepatotoxicity by suppressing CYP2E1 and activating Nrf2 in mouse liver
- Glabridin attenuates paracetamol-induced liver injury in mice via CYP2E1-mediated inhibition of oxidative stress
- A regulatory variant in CYP2E1 affects the risk of lung squamous cell carcinoma
- Insulin resistance enhances binge ethanol-induced liver injury through promoting oxidative stress and up-regulation CYP2E1
- Association between CYP2E1 polymorphisms and risk of gastric cancer: An updated meta‑analysis of 32 case‑control studies
- CYP2E1 gene polymorphisms related to the formation of coronary artery lesions in Kawasaki disease
- Insights into insulin-mediated regulation of CYP2E1: miR-132/-212 targeting of CYP2E1 and role of phosphatidylinositol 3-kinase, Akt (protein kinase B), mammalian …
- CYP1AI and CYP2E1 gene polymorphisms may increase susceptibility to Oral Submucous Fibrosis among betel quid chewers of Eastern India
- Extract of Jasminum grandiflorum L. alleviates CCl4-induced liver injury by decreasing inflammation, oxidative stress and hepatic CYP2E1 expression in mice
- Effect of CYP2E1 gene polymorphisms on lamb odor and flavor in Indonesian sheep
- Coordinate regulation of CYP2E1 by β-catenin-and hepatocyte nuclear factor 1α-dependent signaling
- Bortezomib alleviates drug-induced liver injury by regulating CYP2E1 gene transcription
- Association between polymorphisms in the CYP1A1, CYP2E1 and GSTM1 genes, and smoking, alcohol and upper digestive tract carcinomas in a high …
- Intracellular ethanol‐mediated oxidation and apoptosis in HepG2/CYP2E1 cells impaired by two active peptides from seahorse (Hippocampus kuda bleeler) protein …
- The genetic profiles of CYP1A1, CYP1A2 and CYP2E1 enzymes as susceptibility factor in xenobiotic toxicity in Turkish population
- CYP2E1 PstI/RsaI polymorphism and interaction with alcohol consumption in hepatocellular carcinoma susceptibility: evidence from 1,661 cases and 2,317 controls
- A novel role of CYP2E1 in human megakaryocyte development
- Inhibition of CYP2E1 and activation of Nrf2 signaling pathways by a fraction from Entada africana alleviate carbon tetrachloride-induced hepatotoxicity
- Metabolic activation by human arylacetamide deacetylase, CYP2E1, and CYP1A2 causes phenacetin-induced methemoglobinemia
- The LRP6 functional mutation rs2302685 contributes to individual susceptibility to alcoholic liver injury related to the Wnt/β-catenin-TCF1-CYP2E1 signaling pathway
- Hepatoprotective Effect of Loquat Leaf Flavonoids in PM2.5-Induced Non-Alcoholic Fatty Liver Disease via Regulation of IRs-1/Akt and CYP2E1/JNK Pathways
- … ‐en‐Y gastric bypass surgery influenced pharmacokinetics of several drugs given as a cocktail with the highest impact observed for CYP1A2, CYP2C8 and CYP2E1 …
- Alcohol intake and folate antagonism via CYP2E1 and ALDH1: Effects on oral carcinogenesis
- High CYP2E1 activity aggravates hepatofibrosis by limiting macrophage polarization towards the M2 phenotype
- … of interactions of cathinone with human recombinant cytochrome P450 CYP (1A2), CYP2A6, CYP2B6, CYP2C8, CYP2C19, CYP2E1, CYP2J2, and CYP3A5
- Upregulation of CYP2E1 expression causes oxidative damage induced by 2-chloroethanol in primary cultured rat astrocytes
- Relationships among N, N-dimethylformamide exposure, CYP2E1 and TM6SF2 genes, and non-alcoholic fatty liver disease
- Epididymal CYP2E1 plays a critical role in acrylamide-induced DNA damage in spermatozoa and paternally mediated embryonic resorptions
- CYP2E1, oxidative stress and MAPK signaling pathways in alcohol-induced hepatotoxicity
- Romidepsin (FK228) in a mouse model of lipopolysaccharide-induced acute kidney injury is associated with down-regulation of the CYP2E1 gene
- Effects of insulin treatment on hepatic CYP1A1 and CYP2E1 activities and lipid peroxidation levels in streptozotocin-induced diabetic rats
- The CYP2E1 inhibitor DDC up-regulates MMP-1 expression in hepatic stellate cells via an ERK1/2-and Akt-dependent mechanism
- CYP17A1 and CYP2E1 variants associated with high altitude polycythemia in Tibetans at the Qinghai-Tibetan Plateau
- Interleukin-6 mediated upregulation of CYP1B1 and CYP2E1 in colorectal cancer involves DNA methylation, miR27b and STAT3
- … of 95% khat ethanol extract (KEE) on human recombinant cytochrome P450 (CYP) 1A2, CYP2A6, CYP2B6, CYP2C8, CYP2C19, CYP2E1, CYP2J2 and CYP3A5
- Genetic polymorphism of the drug-metabolizing enzyme Cytochrome P4502E1 (CYP2E1) in a healthy Saudi population
- Oxidative stress caused by a SOD1 deficiency ameliorates thioacetamide-triggered cell death via CYP2E1 inhibition but stimulates liver steatosis
- Synonymous mutation rs2515641 affects CYP2E1 mRNA and protein expression and susceptibility to drug-induced liver injury
- Increased Expression of CYP2E1 gene in gastric cancer may be a molecular marker for mazandaran province population
- Relative contributions of CYP1A2 and CYP2E1 to the bioactivation and clearance of 4-aminobiphenyl in adult mice
- CYP2E1, oxidative stress, post-translational modifications and lipid metabolism
- CYP2E1 RsaI and 96-bp insertion genetic polymorphisms associated with risk for colorectal cancer
- … stem cells rescue rat hippocampal cells from aluminum oxide nanoparticle-induced apoptosis via regulation of P53, Aβ, SOX2, OCT4, and CYP2E1
- High-Risk HPV with Multiple Infections Promotes CYP2E1, Lipoperoxidation and Pro-Inflammatory Cytokines in Semen of Asymptomatic Infertile Men
- Covalent modification and time-dependent inhibition of human CYP2E1 by the meta-isomer of acetaminophen
- Impact of CYP2E1, GSTA1 and GSTP1 gene variants on serum alpha glutathione S-transferase level in patients undergoing anaesthesia
- Effects of Flavonoids in Lysimachia clethroides Duby on the Activities of Cytochrome P450 CYP2E1 and CYP3A4 in Rat Liver Microsomes
- Involvement of CYP2E1 in the course of brain edema induced by subacute poisoning with 1, 2-Dichloroethane in mice
- Garlic oil alleviated ethanol-induced fat accumulation via modulation of SREBP-1, PPAR-α, and CYP2E1
- DNA damage in peripheral blood lymphocytes and association with polymorphisms in the promoter region of the CYP2E1 gene in alcoholics from Central Brazil
- CYP2E1 RsaI/PstI polymorphism and liver cancer risk among east Asians: a HuGE review and meta-analysis
- Inhibition of CYP2E1 With Propylene Glycol Does Not Protect Against Hepatocellular Injury in Human Acetaminophen Daily‐Dosing Model
- Ferric citrate CYP2E1-independently promotes alcohol-induced apoptosis in HepG2 cells via oxidative/nitrative stress which is attenuated by pretreatment with …
- Functional PstI/RsaI polymorphisms in the CYP2E1 gene among south Indian populations
- Interactions between CYP2E1 and CYP2B4: effects on affinity for NADPH-cytochrome P450 reductase and substrate metabolism
- … quantification of metabolic reaction products catalysed by CYP2E1 enzyme activity: inhibitory effect of cytochrome P450 enzyme CYP2E1 by salicylic acid in rat liver …
- Genetic variation of ABCB1 (rs1128503, rs1045642) and CYP2E1 rs3813867 with the duration of tuberculosis therapy: a pilot study among tuberculosis …
- Lrp6 Genotype affects Individual Susceptibility to Nonalcoholic Fatty Liver Disease and Silibinin Therapeutic Response via Wnt/β-catenin-CYP2E1 Signaling
- RORα switches transcriptional mode of ERRγ that results in transcriptional repression of CYP2E1 under ethanol-exposure
- The polymorphism rs2480258 within CYP2E1 is associated with different rates of acrylamide metabolism in vivo in humans
- Quercetin prevents type 1 diabetic liver damage through inhibition of CYP2E1
- Protective effect of Ornithogalum saundersiae Ait (Liliaceae) against acetaminophen-induced acute liver injury via CYP2E1 and HIF-1α
- Involvement of hepatic stellate cell cytoglobin in acute hepatocyte damage through the regulation of CYP2E1-mediated xenobiotic metabolism
- RsaI but not DraI polymorphism in CYP2E1 gene increases the risk of gastrointestinal cancer in Malaysians: a case–control study
- Interactions between CYP2E1, GSTZ1 and GSTT1 polymorphisms and exposure to drinking water trihalomethanes and their association with semen quality
- Epilobium hirsutum alters xenobiotic metabolizing CYP1A1, CYP2E1, NQO1 and GPx activities, mRNA and protein levels in rats
- Association of GSTM1, GSTT1, GSTP1 and CYP2E1 single nucleotide polymorphisms with colorectal cancer in Iran
- Human CYP2E1-dependent mutagenicity of mono-and dichlorobiphenyls in Chinese hamster (V79)-derived cells
- The Inhibition Effect of the Seaweed Polyphenol, 7-Phloro-Eckol from Ecklonia Cava on Alcohol-Induced Oxidative Stress in HepG2/CYP2E1 Cells
- CYP2E1 testis expression and alcohol-mediated changes of rat spermatogenesis indices and type I collagen
- π–π Stacking mediated drug–drug interactions in human CYP2E1
- Modulation of mRNA expression and activities of xenobiotic metabolizing enzymes, CYP1A1, CYP1A2, CYP2E1, GPx and GSTP1 by the Salicornia freitagii extract in …
- Pretreatment with turmeric modulates the inhibitory influence of cisplatin and paclitaxel on CYP2E1 and CYP3A1/2 in isolated rat hepatic microsomes
- Characterization of polymorphisms of genes ADH2, ADH3, ALDH2 and CYP2E1 and relationship to the alcoholism in a Colombian population
- Correlation between spermatogenesis disorders and rat testes CYP2E1 mRNA contents under experimental alcoholism or type I diabetes
- Chronic administration of caderofloxacin, a new fluoroquinolone, increases hepatic CYP2E1 expression and activity in rats
- CYP2E1 polymorphism, acetylator profiles and drug-induced liver injury incidence of Indonesian tuberculosis patients
- Aspartame administration and insulin treatment altered brain levels of CYP2E1 and CYP3A2 in streptozotocin-induced diabetic rats
- Increased oxidative stress and toxicity in ADH and CYP2E1 overexpressing human hepatoma VL-17A cells exposed to high glucose
- Targeted delivery of CYP2E1 recombinant adenovirus to malignant melanoma by bone marrow-derived mesenchymal stem cells as vehicles
- Effects of ethanol on CYP2E1 levels and related oxidative stress using a standard balanced diet
- Genotype-Environment Interaction Analysis of NQO1, CYP2E1, and NAT2 Polymorphisms and the Risk of Childhood Acute Lymphoblastic Leukemia: A …
- Polymorphisms in CYP2E1, GSTM1 and GSTT1 and anti-tuberculosis drug-induced hepatotoxicity
- Effect of eurycomanone on cytochrome P450 isoforms CYP1A2, CYP2A6, CYP2C8, CYP2C9, CYP2C19, CYP2E1 and CYP3A4 in vitro
- CYP2E1 genetic polymorphism with dietary, tobacco, alcohol habits, H. pylori infection status and susceptibility to stomach cancer in Mizoram, India
- Caralluma umbellata Haw. protects liver against paracetamol toxicity and inhibits CYP2E1
- CYP2E1 rs2031920, COMT rs4680 polymorphisms, cigarette smoking, alcohol use and lung cancer risk in a Japanese population
- Genetic variations in the drug metabolizing enzyme, CYP2E1, among various ethnic populations of Pakistan
- Persimmon vinegar and its fractions protect against alcohol-induced hepatic injury in rats through the suppression of CYP2E1 expression
- … experimental and theoretical study of ROS scavenging by organosulfur compounds from garlic: In silico analysis of metabolic pathways and interactions on CYP2E1
- Cytochrome P450 genes (CYP2E1 and CYP1A1) variants and susceptibility to chronic hepatitis B virus infection
- Does CYP2E1 RsaI/PstI polymorphism confer head and neck carcinoma susceptibility?: A meta-analysis based on 43 studies
- … -2-O-β-D-glucoside exacerbates acetaminophen-induced hepatotoxicity by inducing hepatic expression of CYP2E1, CYP3A4 and CYP1A2
- Association of mitochondrial deoxyribonucleic acid mutation with polymorphism in CYP2E1 gene in oral carcinogenesis
- Liver cancer-related gene CYP2E1 expression in HBV transgenic mice with acute liver injury
- Evolution of camel CYP2E1 and its associated power of binding toxic industrial chemicals and drugs
- Mannan‐binding lectin attenuates acetaminophen‐induced hepatotoxicity by regulating CYP2E1 expression via ROS‐dependent JNK/SP1 pathway
- Frequency distribution of high risk alleles of CYP2C19, CYP2E1, CYP3A4 genes in Haryana population
- CYP2E1 T7632A and 9-bp insertion polymorphisms and colorectal cancer risk: a meta-analysis based on 4,592 cases and 5,918 controls
- Comparing the protective effects of three sulfur compounds against acrylonitrile-induced acute toxicity in CYP2E1-induced rats
- CYP2C8 and CYP2E1 genetic variants increase risk of tuberculosis in northwest Chinese Han population
- Polymorphisms in the CYP2E1 and GSTM1 Genes as Possible Protection Factors for Leprosy Patients
- Mutagenic Activity of N‐Nitrosodiethylamine in Cell Lines Expressing Human CYP2E1—Adequacy of Dimethylsulfoxide as Solvent
- Identification of 2-piperidone as a biomarker of CYP2E1 activity through metabolomic phenotyping
- A Systematically Combined Genotype and Functional Combination Analysis of CYP2E1, CYP2D6, CYP2C9, CYP2C19 in Different Geographic Areas of …
- Association between genetic variants in CYP2E1 and CTRC genes and susceptibility to alcoholic pancreatitis: A systematic review and meta-analysis
- Direct sequencing and comprehensive screening of genetic polymorphisms on CYP2 family genes (CYP2A6, CYP2B6, CYP2C8, and CYP2E1) in five ethnic …
- Changes in coumarin kinetics and subcellular localization of CYP2E1 contribute to bile duct damage and reduce hepatocellular damage after repeated administration …
- Ultrasensitive quantification of the CYP2E1 probe chlorzoxazone and its main metabolite 6-hydroxychlorzoxazone in human plasma using ultra performance liquid …
- Human CYP2E1-dependent and human sulfotransferase 1A1-modulated induction of micronuclei by benzene and its hydroxylated metabolites in Chinese hamster …
- Age-dependent features of CYP3A, CYP2C, and CYP2E1 functioning at metabolic syndrome
- Association of CYP2E1 and NAT2 polymorphisms with lung cancer susceptibility among Mongolian and Han populations in the Inner Mongolian region
- Kinetic characterizations of diallyl sulfide analogs for their novel role as CYP2E1 enzyme inhibitors
- In vitro evaluation of structural analogs of diallyl sulfide as novel CYP2E1 inhibitors for their protective effect against xenobiotic-induced toxicity and HIV …
- N-Hydroxylation of 4-Aminobiphenyl by CYP2E1 Produces Oxidative Stress in a Mouse Model of Chemically Induced Liver Cancer
- Investigation of CYP2E1 and Caspase-3 Gene Expressions in COVID-19 patients
- How mutations affecting the ligand-receptor interactions: a combined MD and QM/MM calculation on CYP2E1 and its two mutants
- Over-expression of CYP2E1 mRNA and protein: implications of xenobiotic induced damage in patients with de novo acute myeloid leukemia with inv (16)(p13. 1q22); …
- CYP2E1 and GSTM1 gene polymorphisms, environmental factors, and the susceptibility to lung cancer
- Susceptibility to the acute toxicity of acrylonitrile in streptozotocin-induced diabetic rats: protective effect of phenethyl isothiocyanate, a phytochemical CYP2E1 …
- Rdh13 deficiency weakens carbon tetrachloride-induced liver injury by regulating Spot14 and CYP2E1 expression levels
- 4-Fluoromethamphetamine (4-FMA) induces in vitro hepatotoxicity mediated by CYP2E1, CYP2D6, and CYP3A4 metabolism
- In-Vitro CYP3A4, CYP2E1 and UGT activity in human liver microsomes by Strobilanthes crispus leaf extracts
- Red meat intake, CYP2E1 and PPARγ polymorphisms, and colorectal cancer risk
- The effects of non-esterified fatty acids and β-hydroxybutyrate on the hepatic CYP2E1 in cows with clinical ketosis
- Association of GSTM1, GSTT1 and CYP2E1 gene polymorphisms with antituberculosis drug induced hepatotoxicity in North Indian population
- Contributions of caspase-8 and-9 to liver injury from CYP2E1-produced metabolites of halogenated hydrocarbons
- Histone acetylation and arachidonic acid cytotoxicity in HepG2 cells overexpressing CYP2E1
- Crosstalk between CYP2E1 and PPARα substrates and agonists modulate adipose browning and obesity
- CYP2E1 inhibition and NF_κB Signaling Pathway are Involved in the Protective Molecular Effect of Origanum floribundum against Acetaminophen-induced …
- The polymorphism of CYP2E1 Rsa I/Pst I gene and susceptibility to respiratory system cancer: a systematic review and meta-analysis of 34 studies
- Association analysis of SNPs in the porcine CYP2E1 gene with skatole, indole, and androstenone levels in backfat of a crossbred pig population
- Fermented Curcuma longa L. Prevents Alcoholic Fatty Liver Disease in Mice by Regulating CYP2E1, SREBP-1c, and PPAR-α
- Structure-toxicity relationship study of para-halogenated styrene analogues in CYP2E1 transgenic cells
- 1, 3-Butadiene-induced mitochondrial dysfunction is correlated with mitochondrial CYP2E1 activity in Collaborative Cross mice
- CYP2E1 gene rs6413420 polymorphism was first found in the Bouyei ethnic group of China
- Chemical characteristics for optimizing CYP2E1 inhibition
- Hepatoprotective effect of 10% ethanolic extract from Curdrania tricuspidata leaves against ethanol-induced oxidative stress through suppression of CYP2E1
- Association between CYP2E1 and GOT2 gene polymorphisms and susceptibility and low-dose N, N-dimethylformamide occupational exposure-induced liver injury
- A New CYP2E1 Inhibitor, 12-Imidazolyl-1-dodecanol, Represents a Potential Treatment for Hepatocellular Carcinoma
- Novel CYP2E1 haplotype identified in a South African cohort
- Adrenergic blocker terazosin potentially suppresses acetaminophen induced-acute liver injury in animal models via CYP2E1 gene
- Human CYP2E1‐dependent mutagenicity of benzene and its hydroxylated metabolites in V79‐derived cells: Suppression and enhancement by ethanol pretreatment
- Vitamin E in vivo studies on the activity of antioxidant enzymes and CYP2E1 expression in high PUFA-treated brains
- Identification of cytochrome CYP2E1 as critical mediator of alcohol effects on steatotic hepatocytes
- A study on the optimization of CYP2E1 enzyme activity in C57Bl/6 mouse brain and liver
- Chemoprotective Effect of Daphnetin Against Benzene-induced Leukemia via Alteration of CYP2E1
- Contribution of CYP2E1 polymorphism to aging in the mechanical workshop workers
- Ethanol-induced oxidative stress modifies inflammation and angiogenesis biomarkers in retinal pigment epithelial cells (ARPE-19): role of CYP2E1 and its inhibition …
- The Action of Cytochrome b5 on CYP2E1 and CYP2C19 Activities Requires Anionic Residues D58 and D65
- … effect of seed coat ofEuryale ferox extract in non-alcoholic fatty liver disease induced by high-fat diet in mice by increasing IRs-1 and inhibiting CYP2E1
- Kaempferol’s protective effect on ethanol-induced mouse primary hepatocytes injury involved in the synchronous inhibition of SP1, Hsp70 and CYP2E1
- Targeted CYP2E1 quantification and its correlation to currently acceptable clinical biochemical indices
- Research on the progress of alcoholic liver disease pathogenesis related to CYP2E1
- Effect of jujube on the expression of CYP2E1 and TNF-alpha in the hepatic tissue of mice with alcoholic liver disease
- Establishment of a p-nitrophenol oxidation-based assay for the analysis of CYP2E1 activity in intact hepatocytes in vitro
- No association of CYP2E1 genetic polymorphisms with alcohol dependence in Han Taiwanese population
- Roles of CYP1A1 and CYP2E1 gene polymorphisms in Oral submucous fibrosis
- Significant genotype difference in the CYP2E1 PstI polymorphism of indigenous groups in Sabah, Malaysia with Asian and non-Asian populations
- Camelus dromedarius putative cytochrome P450 enzyme CYP2E1: complete coding sequence and phylogenetic tree
- Alteration of CYP2E1, DBN1, DNMT1, miRNA-335, miRNA-21, c-Fos and Cox-2 gene expression in prefrontal cortex of rats’ offspring submitted to prenatal ethanol …
- Effect of water miscible organic solvents on p-nitrophenol hydroxylase (CYP2E1) activity in rat liver microsomes
- Updated meta-analysis of the association between CYP2E1 RsaI/PstI polymorphisms and lung cancer risk in Chinese population
- Transgenic plant regeneration of tobacco (Nicotiana tabacum) haboring mammalian CYP2E1 gene
- Relationship of ALDH2 rs671 and CYP2E1 rs2031920 with hepatocellular carcinoma susceptibility in East Asians: a meta-analysis
- Effect of BI-1 on insulin resistance through regulation of CYP2E1
- Propolis alleviates 4‐aminobiphenyl‐induced oxidative DNA damage by inhibition of CYP2E1 expression in human liver cells
- Protective effects of garlic oil against 1, 3-dichloro-2-propanol-induced hepatotoxicity: Role of CYP2E1 and MAPKs
- Pyridoxine deficiency modulates benzene inhalation-induced hematotoxicity associated with hepatic CYP2E1 activity in B6C3F1 mice
- Polymorphisms in alcohol dehydrogenase (ADH1) and cytochrome p450 2E1 (CYP2E1) genes in patients with cirrhosis and/or hepatocellular carcinoma
- CYP2E1: the anesthesia enzyme
- Meta-analysis of CYP2E1 polymorphisms in liver carcinogenesis
- Pharmacological blockage of CYP2E1 and alcohol-mediated liver cancer: is the time ready?
- CYP2E1 RsaI/PstI polymorphisms contributed to oral cancer susceptibility: a meta-analysis
- Note of clarification of data on the association between CYP2E1 RsaI polymorphism and lung cancer risk
- Environmental exposure to benzene: evaluation of urinary S-PMA and polymorphism (CYP2E1-1293G> C and NQO1 609C> T) in Campos Elíseos residents …
- Dietary omega-3 polyunsaturated fatty acids alter fatty acid composition of lipids and CYP2E1 expression in rat liver tissue
- CYP2E1 and ALDH2 gene polymorphisms in squamous cell head and neck Cancer in the Turkish population
- Plasma cholinesterase activity is influenced by interactive effect between omethoate exposure and CYP2E1 polymorphisms
- Study on inhibitory effect of water extract of Polygonum multiflorum on CYP1A2 and CYP2E1 enzymatic activities and mRNA expressions in rat liver
- Effects of aqueous extract of Polygoni Multiflori Radix and its main constituents on expression of mRNA of CYP1A2, CYP2C9, and CYP2E1 in human liver L02 cells
- Association between CYP2E1 genetic polymorphisms and urinary cancer risk: a meta-analysis
- mRNA Expression of CYP2E1, CYP2A19, CYP1A2, HSD3B, SULT1A1 and SULT2A1 genes in surgically castrated, immunologically castrated, entire male and female …
- Investigation of cytochrome p450 CYP1A2, CYP2D6, CYP2E1 and CYP3A4 gene expres-sions and polymorphisms in alcohol with-drawal
- 2‐mercaptobenzothiazole generates γ‐H2AX via CYP2E1‐dependent production of reactive oxygen species in urothelial cells
- CYP2E1-and TNFalpha/LPS-induced oxidative stress and MAPK signaling pathways in alcoholic liver disease
- Study of CYP2E1 gene RsaI/PstI polymorphisms in patients with gastric cancer in north of Iran
- Inhibitory potency of 4-carbon alkanes and alkenes toward CYP2E1 activity
- Quantification of CYP2E1 in rat liver by UPLC-MS/MS-based targeted proteomics assay: a novel approach for enzyme activity assessment
- Mechanism and clinical significance of HBx-mediated inhibition of CYP2E1 expression in the human HepG2 hepatoma cell line
- Differences in butadiene adduct formation between rats and mice not due to selective inhibition of CYP2E1 by butadiene metabolites
- Down-regulation of the expression of alcohol dehydrogenase 4 and CYP2E1 by the combination of α-endosulfan and dioxin in HepaRG human cells
- Allelic and genotypic frequencies of NAT2, CYP2E1, and AADAC genes in a cohort of Peruvian tuberculosis patients
- Induction of rat hepatic CYP2E1 expression by arecoline in vivo
- Ethanol-induced CYP2E1 Expression is Reduced by Lauric Acid via PI3K Pathway in HepG2 Cells
- The physiological mechanism of improved formaldehyde resistance in Petunia hybrida harboring a mammalian CYP2E1 gene
- Obesity‐induced CYP2E1 activity in children
- CYP2E1, GSTM1, and GSTT1 genetic polymorphisms and their associations with susceptibility to antituberculosis drug-induced liver injury in Thai …
- Mammalian CYP2E1 gene triggered changes of relative ions fluxes, CaM content and genes expression profiles in Petunia hybrida cells to enhance resistance to …
- Losartan effects on liver cytochromes CYP3A, CYP2C and CYP2E1 functioning at metabolic syndrome in young and adult rats
- All trans retinoic acid modulates TNF-α and CYP2E1 pathways and enhances regression of ethanol-induced fibrosis markers in hepatocytes and HSCs in abstaining …
- CYP2E1 and Parkinson’s disease in a MPTP-induced C57BL/6 mouse model
- End-product inhibition of skatole-metabolising enzymes CYP1A, CYP2A19 and CYP2E1 in porcine and piscine hepatic microsomes
- ZSCAN25 and CYP2E1 polymorphisms is risk factors for ischemic stroke in a Chinese Han population: a case control study
- CYP2E1 activity and children with obesity: possible confounding factors
- Effects of SNPs (CYP1B1* 2 G355T, CYP1B1* 3 C4326G, and CYP2E1* 5 G-1293C), smoking, and drinking on susceptibility to laryngeal cancer among Han …
- Exogenous toluene gas removal improvement in recombinant rabbit cytochrome P450 2E1 (CYP2E1)-transgenic Ardisia pusilla DC
- CYP2E1 polymorphisms and colorectal cancer
- Cytochrome P450 CYP2E1 Suppression Ameliorates Cerebral Ischemia Reperfusion Injury. Antioxidants 2021, 10, 52
- Association of CYP2E1 and CYP1A1m2 (BsrD1) polymorphisms with cytogenetic biomarkers in petrol pump workers
- Ephedra water decoction and cough tablets containing ephedra and liquorice induce CYP1A2 but not CYP2E1 hepatic enzymes in rats
- Association of CYP1A1 and CYP2E1 gene polymorphisms with prostate cancer in a Lebanese population
- Anti-tuberculosis drug-induced liver injury correlated with the methylation in the promoter regions of CYP2E1 and GSTM1
- Unraveling CYP2E1 haplotypes in alcoholics from Central Brazil: a comparative study with 1000 genomes population
- The effects of bovine serum albumin on kinetic characterization of human liver microsomal CYP2C19 and CYP2E1 activities
- The effect of changes in CYP2E1 activity in the liver on toxicity and carcinogenicity of diethylnitrosamine in mice
- Association of radiation risk in the second and third generations with polymorphisms in the genes CYP1A1, CYP2E1, GSTP1 and changes in the thyroid
- Correction to: CYP2E1-mediated oxidative stress regulates HO-1 and GST expression in maneb-and paraquat-treated rat polymorphonuclear leukocytes
- Modulation of CYP2E1 metabolic activity in a cohort of confirmed caffeine ingesting pregnant women with preterm offspring
- M1 Polarization bias and subsequent NASH progression is attenuated by nitric oxide donor DETA NONOate via inhibition of CYP2E1 induced oxidative stress in …
- Effect of Dietary Supplementation with Dried Tuber of Jerusalem Artichoke on Skatole Level in Backfat and CYP2E1 mRNA Expression in Liver of Boars
- Roles of CYP2E1 in liver damage induced by 1, 2-dichloroethane
- An improved in vitro method for screening toxin and medicine targeting CYP2E1
- … : Nanoformulated SOD1 ameliorates the combined NASH and alcohol-associated liver disease partly via regulating CYP2E1 expression in adipose tissue and …
- The Association of CYP2E1 Polymorphism and Environmental Factor in Nasopharyngeal Carcinoma Patients
- Similar effect of quercetin on CYP2E1 and CYP2C9 activities in humans?
- Effect of Er Chen Tang on CYP2E1 and mitochondrial energy metabolism in nonalcoholic fatty liver disease
- Requirement prediction for toluene detox with foods intake rich in CYP2E1 enzyme and glycine to prevent nerve and kidney damage at shoe home industry …
- Association of CYP1A1 and CYP2E1 gene polymorphism with risk of arsenism caused by coal-burning
- Insights into insulin-mediated regulation of CYP2E1: miR 132/212 targeting of CYP2E1 and role of PI3-K, Akt, mTOR signaling in regulating miR132/212 and miR 122 …
- Polymorphisms of CYP2E1 rs2031920 is not Associated with Risk of Nasopharyngeal Carcinoma in Minangkabau Ethnic Group
- Silver Nanoparticle-Doped Poly (8-Anilino-1-Naphthalene Sulphonic Acid)/CYP2E1 Nanobiosensor for Isoniazid-A First Line Anti-Tuberculosis Drug
- Correlation between genetic polymorphisms of CYP2E1 DraⅠ and susceptibility of gastric cancer in Qinghai province
- Genotype and phenotype polymorphisms of NAT2 and CYP2E1 in the Han Chinese pediatric population
- Identification of Novel CYP2E1 Inhibitor to Investigate Cellular and Exosomal CYP2E1-Mediated Toxicity
- Lack of association of CYP2E1 and CYP1A1 polymorphisms with osteoporosis in postmenauposal women
- TRPV4 attenuates M1 polarization and subsequent NASH progression by stalling CYP2E1-mediated redox toxicity via eNOS.
- Comment on:“Morbidly Obese Patients Exhibit Increased CYP2E1-Mediated Oxidation of Acetaminophen”
- Zebrafish have an ethanol-inducible hepatic 4-nitrophenol hydroxylase that is not CYP2E1-like
- Association between the TP53 and CYP2E1* 5B gene polymorphisms and non-small cell lung cancer
- THE ROLE OF CYP2E1 POLYMORPHISM IN THE ACTIVATION OF PROCARCINOGEN METABOLISM OF NASOPHARYNGEAL CARCINOMA
- CYP2E1 immunoglobulin G4 subclass antibodies after desflurane anesthesia
- Effect of Capsosiphon fulvescens on ethanol-induced liver damage in HepG2 cells over expressing CYP2E1
- Effect of Salviae Miltiorrhizae Radix et Rhizoma and Carthami Flos before and after compatibility on activities of CYP1A2, CYP2E1, and CYP3A4 from rat liver …
- Chemoprotective Effect of Daphnetin against Benzene Induced Leukemia Cancer via Alteration of CYP2E1
- Modulatory effects of persimmon vinegar and its fractions on hepatic immune response and CYP2E1 activation in chronically alcohol drinking rats (649.4)
- Ekspresija CYP2E1 u testisima štakora i alkoholom prouzrokovane promjene indeksa spermatogeneze i kolagena tipa I
- Alcohol-Induced Increase in the Content of CYP2E1 in Human Liver Microsomes Causes a Multifold Activation of CYP3A4 and Attenuates its Cooperativity
- CYP2E1 Associated Dysregulation of Nucleotide Excision Repair (NER) Process In Hepatocellular Carcinoma
- Heliotropium undulatum attenuates hydrazine induced hepatotoxicity: involvement of cytochrome P450 CYP2E1 and oxidative stress
- Maternal protein restriction during lactation modulated the expression and activity of rat offspring hepatic CYP1A1, CYP1A2, CYP2B1, CYP2B2, and CYP2E1 …
- In Silico Approach for Hepatoprotective Activity of Piper crocatum Leaf Towards CYP2E1 Protein:(TJPS-2020-0154. R2)
- Chronic ethanol and high glucose inducible CYP2E1 mediated oxidative stress leads to greater cellular injury in VL-17A cells: a potential mechanism for liver injury …
- Extracts of Poria cocos polysaccharides improves alcoholic liver disease in mice via CYP2E1 and NF-κB inflammatory pathways
- Liver Tissue-specific Genes IGFALS, CYP3A4, SLC22A1 and CYP2E1 May be Associated with Poor Prognosis of Liver Cancer
- CYP2E1-DEPENDENT VARIATIONS IN HEPATOCYTES DAMAGE DURING TREATMENT OF TUBERCULOSIS
- Higher CYP2E1 activity is a risk factor for hepatocarcinogenesis
- Expression of CYP2E1 in different brain regions during the formation of toxic cerebral edema induced by 1, 2-DCE in mice and its effect on cerebral edema formation
- Cloning and bioinformatics revealed molecular characterisation of CYP2E1 gene from bactrian camel (Camelus bactrianus)
- Hepatotoxicity Risk Profile of Indonesian Due to Polymorphism of NAT2 and CYP2E1 in Isoniazid Metabolism
- The Polymorphism and Expression of CYP2E1 Gene and Its Relation to Carcass and Meat Quality of Indonesian Lamb
- The regulation of CYP2E1 gene expression and its role in breast cancer
- Effect of grapefruit juice on CYP2E1 gene expression in obese and control rats
- CYP2E1 mediated ethanol metabolism in ARPE-19 cells.
- Correction: Drug targeting CYP2E1 for the treatment of early-stage alcoholic steatohepatitis
- Non-additive effects of changing the cytochrome P450 ensemble: incorporation of CYP2E1 into human liver microsomes and its impact on CYP1A2
- The correlation between CYP2E1 and CYP1A1 genotypes with the susceptibility of HBV infection in northern Guangzhou people
- COMPARISON OF POLYMORPHISM rs2070672 CYP2E1 GENE PROPORTION IN EARLY AND ADVANCED STAGE OF UNDIFFERENTIATED TYPE …
- Crosstalk between CYP2E1 and CYP3A enzymes and its Possible Involvement in Alcohol-Drug Interactions.
- MicroRNA‐122 protects mice and human hepatocytes from acetaminophen toxicity by regulating CYP1A2 and CYP2E1 expression
- Evaluation of smoke burning AnbarNesara on changes of the gene expression of P53 and CYP2E1 in human liver cancer cells
- Profile of retinal pigment epithelium response to ethanol: Role of CYP2E1
- CYP2E1 activity on ARPE-19 cells: New approach to RPE ethanol metabolism
- Povezanost polimorfizama gena TP53 i CYP2E1* 5B s nemikrocelularnim karcinomom pluća
- Relationship between CYP2E1 genetic polymorphism and susceptibility of gastric cancer in Hakkaness
- Bioinformatic Analysis of the Main Characteristics and Structure of the Gene Encoding CYP2E1 Protein.
- Response: Similar effect of quercetin on CYP2E1 and CYP2C9 activities in humans?
- … Protects Hepato-Renal Tissues Against Antituberculosis Drugs Induced Toxic Manifestations by Modulating IL-6, IGF-1, CYP2E1, Biochemical and Ultra …
- Expression of CYP2E1 gene in paint workers occupationally exposed to organic solvents
- Results of intensive phase tretament of tuberculosis treatment according to CYP2E1 genotype
- Association of CYP2E1 Gene Polymorphisms with the Risk of Schizophrenia in the Bangladeshi Population
- Expression of CYP2E1 gene in paint workers occupationally exposed to organic solvents
- Enhanced Hepatotoxicity of Extract of Polygoni Multiflori Radix after Inhibition of CYP2E1 and Screening of Toxic Constituents
- Functional correlate of CYP2E1 methylation in chronic exposure to VOCs: promoter methylation vs. 5’UTR methylation
- CYP2E1 recovery is associated with a pericentral fibrosis pattern after repeated CCl4 insults
- Polymorphisms of CYP2E1 rs2031920 is not Associated with Risk of Nasopharyngeal Carcinoma in Minangkabau Ethnic Group. Open Access Maced J Med Sci …
- CYP2E1 activity in cisplatin resistant cancer cells
- Effect of temperature on carp CYP2E1-like isoform activity.
- The Meta Isomer of Acetaminophen Is A Time Dependent Inhibitor of Human CYP2E1
- CYP2E1 substrate inhibition. MECHANISTIC INTERPRETATION THROUGH AN EFFECTOR SITE FOR MONOCYCLIC COMPOUNDS.
- The Oxidative Effect Of Nlrp3 And CYP2E1 In Development Of Renal Failure Associated With Hypertension And Diabetes Mellitus Diseases
- UPREGULATING OF CYP2E1 IN ETHANOL-FED MICE WITH TRANSGENIC OVEREXPRESSION OF CTRP3
- Distribution of single nucleotide polymorphisms of CYP2E1 gene in Congjiang Xiang-pigs.
- Genetic Polymorphism in Promoter Sequence of CYP2E1 Gene in Paint Manufacturing Workers Exposed to Volatile Organic Compounds
- Computational Docking Simulations of Nitroanisole and Nitrophenol with CYP2E1
- TRPV4 Modulates CYP2E1 Function in Nonalcoholic Steatohepatitis Progression
- Genotype and allelic frequencies of CYP2E1* 5B polymorphism in the southwest population of Iran
- Effects of trichloroethylene toxicity on normal human liver cells and hepatocytes with CYP2E1 gene overexpression
- Assessing specificity of indazole derivatives as inhibitors to CYP2E1
- Effects of three kinds of tea beverages on intestinal first-pass effect and liver Cyp3a, CYP2E1 activities in mice
- Nicotinamide N-Oxidation by CYP2E1 in Human Liver Microsomes
- Association of genetic polymorphisms of CYP2E1 and MPO genes with acute leukemia risk: a meta-analysis.
- Effect of Jiangzhiligan Granules on CYP2E1 Gene and Protein Expression of Rat Model with Non-alcoholic Fatty Liver Disease
- Identification of deletions and duplications in the CYP2E1 gene in a population in Goiânia–GO by MLPA.
- Effects of Mailuoning injection on rat activities of CYP1A2, CYP2E1 and CYP3A4 using a three-drug Cocktail approach
- Requirement Prediction for Toluene Detox with Foods Intake Rich in CYP2E1 Enzyme and Glycine to Prevent Nerve and Kidney Damage at Shoe Home …
- CYP2E1 Epigenetic Regulation In Workers Exposed To Low-Level Voc Mixture: Relationship With Nitrosative Stress And Inflammation
- The Inhibitory Effect of the Derris scandens Extract on Cytochrome P450 2E1 (CYP2E1)-associated Aniline-4-Hydroxylase in vitro
- Association of CYP2E1 and CYP1A1m2 (BsrD1) polymorphisms with cytogenetic biomarkers in petrol pump workers
- The Physiological Mechanism of Petunia hybrida Harboring Mammalian CYP2E1 Gene Improving Resistance to Formaldehyde
- Non‐Additive Effects of Changing the Composition of the Cytochrome P450 Ensemble in Human Liver Microsomes: the Focus on CYP2E1 and Alcohol‐Drug …
- Higher chlorzoxazone clearance in obese children compared with none-obese peers, an open-label explorative pharmacokinetic study of CYP2E1 activity
- Cytochrome CYP2E1 is critical for joint effects of alcohol and lipids on hepatocellular steatosis and inflammation
- CYP2E1 and NQO1 genotypes and bladder cancer risk in a Lebanese population
- A study on the effects of Lauric acid on ROS formation and CYP2E1 mRNA expression in alcohol-induced HEPG2 cells
- Research on Association of Genetic Polymorphism of CYP1A1 and CYP2E1, with Susceptibility to Gastric Cancer
- CYP2E1 VNTR genotyping associated to anti–tuberculosis drug-induced hepatotoxicity
- Study on CYP2E1 gene polymorphism and the relationship between methylation level of its promoter region and liver injury induced by anti-tuberculosis drugs in …
- Relative contribution of hepatic CYP3A and CYP2E1 to oxidative stress upon CHIP E3 ligase knockdown
- Effect of Neiyixiao on Hepatic CYP1A2, CYP2E1, CYP3A4 in Rats with Endometriosis
- Bioinformatics of CYP2E1 CpG intron methylation sites and application to HAR1-RELN sequence analysis
- Effect of flavonoids extract from apocynum venetum tea on CYP2E1 in mice.
- CYP2E1 is a central mediator for the synergistic effects of alcohol and free fatty acids on hepatocellular steatosis and inflammation
- Acetaminophen and Isoniazid treatment leads to oxidative stress and cytotoxicity in cerebellar granule neurons possibly by CYP2E1 activation
- Drinking Water Chlorination By-Products and Intra-Uterine Growth Restriction: is there an effect modification of the CYP2E1 G1259C gene polymorphism?
- CYP2E1 PstI polymorphism increases cervical neoplasia risk: a meta-analysis
- Study the Correlation of GSTM1 and CYP2E1 Gene Polymorphism and Genetic Susceptibility to Non-small Cell Lung Cancer in Shenzhen Area
- CONTROL OF BOAR TAINT BY USING GENETIC MARKERS: A SINGLE NUCLEOTIDE POLYMORPHISM IN THE CYP2E1 GENE PROMOTER AFFECTS …
- Binge alcohol promotes acute liver injury through a CYP2E1‐HIF‐1α‐dependent apoptosis pathway in mice and humans (1010.1)
- Effects of cefetamet hydrochloride injection on activity of CYP1A2, CYP3A4 and CYP2E1 in liver microsomes of rats
- Evaluation of genotoxicity of environmental contaminants, production of bio-sensor cell lines and measurment of CYP2E1 enzymatic activity
- B107 TUBERCULOSIS: ISSUES DURING TREATMENT: An Updated Meta-Analysis On CYP2E1 Rsai/psti And Drai Polymorphisms And Risk Of Anti-Tuberculosis …
- An Updated Meta-Analysis On CYP2E1 RsaI/PstI And DraI Polymorphisms And Risk Of Anti-Tuberculosis Induced Hepatotoxicity: Evidence From 26 Studies
- Analysis of Protein and mRNA Expressions of CYP1A1 and CYP2E1 Enzymes In Liver, Colon And Prostate Cancer Cell Lines to Study Drug and Carcinogen …
- Correction: Investigation of Indazole Unbinding Pathways in CYP2E1 by Molecular Dynamics Simulations
- Polimorfismos nos genes NAT2, CYP2E1, GSTT1, GSTM1 e ABCB11 e hepatotoxicidade induzida pela isoniazida
- GENOTYPE POLYMORPHISMS OF NAT2 AND CYP2E1 GENES ASSOCIATED WITH DRUG INDUCED LIVER INJURY (DILI) IN INDONESIAN …
- Effects of nonyphenol exposure during pregnant and lactation period on expressions of CYP2E1 mRNA and protein of hepatic tissues in offspring rats.
- Modulatory effects of persimmon vinegar and its fractions on alcohol-induced inflammatory stress and CYP2E1 expressions in the liver of Wistar rats
- CYP2E1 rs2031920, COMT rs4680 Polymorphisms, Cigarette Smoking, Alcohol Use and Lung Cancer Risk in a Japanese Population
- The role of brain acetaldehyde in drinking preference: Genetic modification of alcohol oxidizing enzymes catalase and CYP2E1 in C57BL/6 mice and their …
- The effect of organic solvents and CYP1A1, CYP2E1, GSTM1 polymorphisms on the development of acute lymphoblastic leukemia in Quebec children
- Nonclassical ROR Alpha Pathway Switches Transcriptional Mode of ERR Gamma that Results in Repression of Alcohol-induced CYP2E1 Expression
- Effects of the plant phenolic quercetin on protein and mRNA CYP1A1, CYP2E1, NQO1 and GST enzymes in colon cancer cell line SW620
- Analysis of protein and mRNA expressions of CYP1A1, CYP2E1, NQO1 and GST enzymes in liver, colon and prostate cancer cell lines to study drug and carcinogen …
- Analysis of ethanol metabolic enzymes in primary human mammary epithelial cells and MCF‐10A cells: possible participation of CYP2E1 in ethanol‐induced oxidative …
- Hepatoprotective Activity of Eugenol, Hesperidin and Lepidium Sativum Alkaloids in Rats with Liver Injury through Attenuating CYP2E1/Nuclear Factor Kappa-B and …
- S29. 1 CORRELATION BETWEEN SPERMATOGENESIS DISORDERS AND CYP2E1 MRNA EXPRESSION IN RATS TESTES FOLLOWING CHRONIC …
- ISALPDC-03: CYP2E1 Regulation of Ethanol-Induced Intestinal miRNAs in Liver Injury
- Comparison of Polymorphism rs3813865 Cytochrome P450 Family 2 Subfamily E Polypeptide 1 (CYP2E1) Gene in Various Clinical Stage of Undifferentiated …
- 0466 The effect of SNPs in the promoter on expression of CYP2E1 gene and boar taint
- Author’s Reply to Reith:“Morbidly Obese Patients Exhibit Increased CYP2E1-Mediated Oxidation of Acetaminophen”
- Regulation of il-1 and TNF-α on metabolic enzyme CYP2E1 in immunological liver injury in rats
- … ALCOHOL AND CANCER SY05-1 CARCINOGENIC ETHENO DNA ADDUCTS GENERATED DURING INFLAMMATION AND CYP2E1 INDUCTION IN VARIOUS …
- Author Correction: Effect of BI-1 on insulin resistance through regulation of CYP2E1
- Correction to The Action of Cytochrome b5 on CYP2E1 and CYP2C19 Activities Requires Anionic Residues D58 and D65
