INSULIN ANTILIPOLYTIC (PREVENTS FAT LOSS)
December 8, 2023DYSBIOSIS
December 8, 2023
- Genomic instability and cancer
- Genomic instability and colon cancer
- Apoptosis and genomic instability
- Genomic instability induced by ionizing radiation
- The connection between transcription and genomic instability
- The role of nuclear architecture in genomic instability and ageing
- Radiation-induced genomic instability
- Genomic instability—the engine of tumorigenesis?
- Genomic instability in laminopathy-based premature aging
- Chromosomal biomarkers of genomic instability relevant to cancer
- Genomic instability and radiation
- Patterns of genomic instability in gastric cancer: clinical implications and perspectives
- Characterization of sporadic colon cancer by patterns of genomic instability
- Genomic instability and tumor progression: mechanistic considerations
- Genomic instability in colorectal cancer: relationship to clinicopathological variables and family history
- Mechanisms of genomic instability in human cancer: insights from studies with human papillomavirus oncoproteins
- Radiation-induced genomic instability and its implications for radiation carcinogenesis
- Genomic instability in Ip and human malignancies
- Genomic instability in Gadd45a-deficient mice
- The role of DNA breaks in genomic instability and tumorigenesis
- Genomic instability and bystander effects: a historical perspective
- Activation of the DNA damage checkpoint and genomic instability in human precancerous lesions
- Heavy metals of relevance to human health induce genomic instability
- Radiation-induced genomic instability: radiation quality and dose response
- Radiation-induced genomic instability in haemopoietic cells
- Radiation-induced DNA damage and delayed induced genomic instability
- Segmental duplications: an’expanding’role in genomic instability and disease
- The onset and extent of genomic instability in sporadic colorectal tumor progression
- The presence of p53 mutations in human osteosarcomas correlates with high levels of genomic instability
- DNA damage tumor suppressor genes and genomic instability
- The impact of a negligent G2/M checkpoint on genomic instability and cancer induction
- Genomic instability and cancer
- Breast tumor copy number aberration phenotypes and genomic instability
- Genomic instability and aging-like phenotype in the absence of mammalian SIRT6
- MicroRNAs and genomic instability
- The role of genomic instability in human carcinogenesis.
- Genomic instability in mice lacking histone H2AX
- Genomic instability induced by high and low LET ionizing radiation
- A role for mitochondrial dysfunction in perpetuating radiation-induced genomic instability
- Progression to cancer in Barrett’s esophagus is associated with genomic instability.
- Genomic instability in repeated sequences is an early somatic event in colorectal tumorigenesis that persists after transformation
- Inactivation of the SR protein splicing factor ASF/SF2 results in genomic instability
- Transient excess of MYC activity can elicit genomic instability and tumorigenesis
- Hypoxia and defective apoptosis drive genomic instability and tumorigenesis
- Radiation-induced genomic instability
- Genomic instability in MycER-activated Rat1A-MycER cells
- Suppression of genomic instability by SLX5 and SLX8 in Saccharomyces cerevisiae
- Small polydispersed circular DNA (spcDNA) in human cells: association with genomic instability
- Increased ionizing radiation sensitivity and genomic instability in the absence of histone H2AX
- DNA helicases, genomic instability, and human genetic disease
- Genomic instability and cancer: networks involved in response to DNA damage
- Mitochondrial dysfunction leads to telomere attrition and genomic instability
- Genomic instability is an early event during the progression pathway of ulcerative-colitis-related neoplasia
- Radiation-induced genomic instability: a paradigm-breaking phenomenon and its relevance to environmentally induced cancer
- Human SHPRH suppresses genomic instability through proliferating cell nuclear antigen polyubiquitination
- Genomic instability and tolerance to alkylating agents.
- Derivation of Human Tumor Cells in Vitro without Widespread Genomic Instability
- Genomic instability and colorectal cancer
- Genomic instability and apoptosis are frequent in p53 deficient young mice
- Telomere dysfunction increases mutation rate and genomic instability
- Is there a common mechanism underlying genomic instability, bystander effects and other nontargeted effects of exposure to ionizing radiation?
- Lethal mutations and genomic instability
- Radiation-induced genomic instability and persisting oxidative stress in primary bone marrow cultures
- Radiation-induced genomic instability and bystander effects: inter-related nontargeted effects of exposure to ionizing radiation
- Chromosomal instability and its relationship to other end points of genomic instability
- Telomere dysfunction as a cause of genomic instability in Werner syndrome
- Evidence of Genomic Instability inCampylobacter jejuni Isolated from Poultry
- Centrosome replication, genomic instability and cancer
- mRNA processing and genomic instability
- Matrix metalloproteinase-induced genomic instability
- Genomic instability and enhanced radiosensitivity in Hsp70. 1-and Hsp70. 3-deficient mice
- The human Ha-ras oncogene induces genomic instability in murine fibroblasts within one cell cycle.
- Centrosome abnormalities, genomic instability and carcinogenic progression
- Inverted DNA repeats: a source of eukaryotic genomic instability
- Overexpression of Eg5 Causes Genomic Instability and Tumor Formation in Mice
- Oxidative DNA Damage Causes Mitochondrial Genomic Instability in Saccharomyces cerevisiae
- Epstein–Barr virus promotes genomic instability in Burkitt’s lymphoma
- Genomic instability and prognosis in breast carcinomas
- c-Myc, genomic instability and disease
- Genomic instability: first step to carcinogenesis.
- Radiation-induced genomic instability: delayed mutagenic and cytogenetic effects of X rays and alpha particles
- Destructive cycles: the role of genomic instability and adaptation in carcinogenesis
- Mitochondrial dysfunction, persistently elevated levels of reactive oxygen species and radiation-induced genomic instability: a review
- Rb inactivation promotes genomic instability by uncoupling cell cycle progression from mitotic control
- Genomic instability, centrosome amplification, cell cycle checkpoints and Gadd45a
- Non-targeted and Delayed Effects of Exposure to Ionizing Radiation: II. Radiation-Induced Genomic Instability and Bystander Effects In Vivo, Clastogenic Factors and …
- Genomic instability and the role of radiation quality
- Genomic instability and bystander effects induced by high-LET radiation
- Defective DNA repair and increased genomic instability in Artemis-deficient murine cells
- Role of genomic instability and p53 in AID-induced c-myc–Igh translocations
- Human papillomaviruses and centrosome duplication errors: modeling the origins of genomic instability
- Diet, lifestyle, and genomic instability in the North Carolina Colon Cancer Study
- Interrelationships amongst radiation-induced genomic instability, bystander effects, and the adaptive response
- Genomic instability in Schistosoma mansoni
- Initiation of apoptosis in cells exposed to medium from the progeny of irradiated cells: a possible mechanism for bystander-induced genomic instability?
- DNA breaks promote genomic instability by impeding proper chromosome segregation
- The genomic structure of the DMBT1 gene: evidence for a region with susceptibility to genomic instability
- Extracellular signaling through the microenvironment: a hypothesis relating carcinogenesis, bystander effects, and genomic instability
- Aneuploidy, the primary cause of the multilateral genomic instability of neoplastic and preneoplastic cells
- Deregulated G1-cyclin expression induces genomic instability by preventing efficient pre-RC formation
- Mutation of Succinate Dehydrogenase Subunit C Results in Increased O2·−, Oxidative Stress, and Genomic Instability
- Genomic instability in cancer
- DNA double-strand breaks, chromosomal rearrangements, and genomic instability
- The Mouse Genomic Instability Mutation chaos1 Is an Allele of Polq That Exhibits Genetic Interaction with Atm
- Reactive oxygen species, DNA damage, and error-prone repair: a model for genomic instability with progression in myeloid leukemia?
- The RAS oncogene induces genomic instability in thyroid PCCL3 cells via the MAPK pathway
- Genomic instability and catalase gene amplification induced by chronic exposure to oxidative stress
- Genomic instability in neoplasia
- Genomic instability and endoreduplication triggered by RAD17 deletion
- Genomic instability and the role of p53 mutations in cancer cells.
- The yeast CDK inhibitor Sic1 prevents genomic instability by promoting replication origin licensing in late G1
- Inactivation of mouse Hus1 results in genomic instability and impaired responses to genotoxic stress
- Genomic instability in cancer
- Genomic instability in the type II TGF-beta1 receptor gene in atherosclerotic and restenotic vascular cells.
- Bloom syndrome, genomic instability and cancer: the SOS-like hypothesis
- Radiation-induced genomic instability and bystander effects: related inflammatory-type responses to radiation-induced stress and injury? A review
- Targeted and nontargeted effects of low-dose ionizing radiation on delayed genomic instability in human cells
- Cell-adhesion-dependent influences on genomic instability and carcinogenesis
- c-Myc-induced genomic instability
- Genomic instability, DNA methylation, and natural selection in colorectal carcinogenesis
- Regulated genomic instability and neoplasia in the lymphoid lineage
- C-myc overexpression and p53 loss cooperate to promote genomic instability
- Improved grading of breast adenocarcinomas based on genomic instability
- BCR/ABL regulates response to DNA damage: the role in resistance to genotoxic treatment and in genomic instability
- RAD50 and NBS1 are breast cancer susceptibility genes associated with genomic instability
- Checkpoint adaptation precedes spontaneous and damage-induced genomic instability in yeast
- Attenuation of radiation-induced genomic instability by free radical scavengers and cellular proliferation
- The ever expanding role for c-Myc in promoting genomic instability
- The role of p53-mediated apoptosis as a crucial anti-tumor response to genomic instability: lessons from mouse models
- Genomic instability of microsatellite repeats and its association with the evolution of chronic myelogenous leukemia [see comments]
- Chromosome breaks and genomic instability
- UV-A induces persistent genomic instability in human keratinocytes through an oxidative stress mechanism
- Genomic instability of the host cell induced by the human papillomavirus replication machinery
- Combing the genome for genomic instability
- End resection initiates genomic instability in the absence of telomerase
- Genomic instability and its role in neoplasia
- Bystander effects in radiation-induced genomic instability
- Increased genomic instability is not a prerequisite for shortened lifespan in DNA repair deficient mice
- Anaphase-promoting complex-dependent proteolysis of cell cycle regulators and genomic instability of cancer cells
- Genomic instability: environmental invasion and the enemies within
- Mechanisms and implications of genomic instability and other delayed effects of ionizing radiation exposure
- Delayed expression of lethal mutations and genomic instability in the progeny of human epithelial cells that survived in a bystander‐killing environment
- 53BP1 and p53 synergize to suppress genomic instability and lymphomagenesis
- Role of telomeres and telomerase in genomic instability, senescence and cancer
- G-rich proto-oncogenes are targeted for genomic instability in B-cell lymphomas
- Spontaneous transformation of human adult nontumorigenic stem cells to cancer stem cells is driven by genomic instability in a human model of glioblastoma
- Outer breast quadrants demonstrate increased levels of genomic instability
- Genomic instability within centromeres of interspecific marsupial hybrids
- Rac1b and reactive oxygen species mediate MMP-3-induced EMT and genomic instability
- Radiation-induced genomic instability is associated with DNA methylation changes in cultured human keratinocytes
- Genomic instability in head and neck cancer patients
- Radiation-induced genomic instability: delayed cytogenetic aberrations and apoptosis in primary human bone marrow cells
- Fusion tyrosine kinases: a result and cause of genomic instability
- Centrosome abnormalities and genomic instability induced by human papillomavirus oncoproteins.
- The RNA binding protein RNPS1 alleviates ASF/SF2 depletion-induced genomic instability
- Multiple mechanisms account for genomic instability and molecular mutation in neoplastic transformation
- Genomic instability within tumor stroma and clinicopathological characteristics of sporadic primary invasive breast carcinoma
- Genomic instability in multiple myeloma: evidence for jumping segmental duplications of chromosome arm 1q
- Poly (ADP-ribose) polymerase gene expression status and genomic instability in human breast cancer.
- Genomic instability occurs in colorectal carcinomas but not in adenomas
- Colonic tumorigenesis in BubR1+/–ApcMin/+ compound mutant mice is linked to premature separation of sister chromatids and enhanced genomic instability
- Regulation of telomere length and suppression of genomic instability in human somatic cells by Ku86
- A role for genomic instability in cellular radioresistance?
- Transforming Growth Factor β1 Suppresses Genomic Instability Independent of a G1 Arrest, p53, and Rb
- Inducible genomic instability: Inducible genomic instability: New insights into the biological effects of ionizing radiation
- Telomere-driven genomic instability in cancer cells
- Long-term genomic instability in human lymphocytes induced by single-particle irradiation
- Cancer: cell structures, carcinogens and genomic instability
- Disruption of β-catenin pathway or genomic instability define two distinct categories of liver cancer in transgenic mice
- p16INK4a Prevents Centrosome Dysfunction and Genomic Instability in Primary Cells
- Disruption of murine Mus81 increases genomic instability and DNA damage sensitivity but does not promote tumorigenesis
- Regions of genomic instability on 22q11 and 11q23 as the etiology for the recurrent constitutional t (11; 22)
- … in mice conditionally mutant for Brca1 exhibit gross genomic instability and centrosome amplification yet display a recurring distribution of genomic imbalances that is …
- Genomic instability in haematopoietic cells of F1 generation mice of irradiated male parents
- Altered methionine metabolism and global DNA methylation in liver cancer: relationship with genomic instability and prognosis
- Genomic instability and tumor stem cells
- Overexpression of DNA polymerase β: a genomic instability enhancer process
- Endogenous expression of phosphorylated histone H2AX in tumors in relation to DNA double-strand breaks and genomic instability
- Genomic instability in histologically normal breast tissues: implications for carcinogenesis
- Genomic instability, aging, and cellular senescence
- Enhanced Genomic Instability and Defective Postreplication Repair in RAD18 Knockout Mouse Embryonic Stem Cells
- Genomic instability in Rhizobium phaseoli
- Second cancers after radiotherapy: any evidence for radiation-induced genomic instability?
- Large-scale genomic instability predicts long-term outcome for women with invasive stage I ovarian cancer
- Genomic instability in human osteoblast cells after exposure to depleted uranium: delayed lethality and micronuclei formation
- A stochastic carcinogenesis model incorporating genomic instability fitted to colon cancer data
- Poly (APD-ribosyl) ation, a DNA damage-driven protein modification and regulator of genomic instability
- Tumor-specific low molecular weight forms of cyclin E induce genomic instability and resistance to p21, p27, and antiestrogens in breast cancer
- Clonal chromosome aberrations and genomic instability in X-irradiated human T-lymphocyte cultures
- p53-mediated apoptosis and genomic instability diseases
- Genomic instability and recurrent breakpoints are main cytogenetic findings in Hodgkin’s disease
- Particulate debris from a titanium metal prosthesis induces genomic instability in primary human fibroblast cells
- Defective DNA repair and increased genomic instability in Cernunnos-XLF-deficient murine ES cells
- Deletion of mouse rad9 causes abnormal cellular responses to DNA damage, genomic instability, and embryonic lethality
- The DNA helicase activity of BLM is necessary for the correction of the genomic instability of bloom syndrome cells
- Plant genomic instability detected by microsatellite-primers
- Role of genomic instability in meningioma progression
- Clinical implications of radiation-induced genomic instability
- V (D) J-mediated translocations in lymphoid neoplasms: a functional assessment of genomic instability by cryptic sites
- Centrosome abnormalities and genomic instability by episomal expression of human papillomavirus type 16 in raft cultures of human keratinocytes
- Genomic instability in phenotypically normal regenerants of medicinal plant Codonopsis lanceolata Benth. et Hook. f., as revealed by ISSR and RAPD markers
- In Vivo Enhancement of Genomic Instability in Minisatellite Sequences of Mouse C3H/10T½ Cells Transformed in Vitro by X-Rays
- Mutations, expression and genomic instability of the H-ras proto-oncogene in squamous cell carcinomas of the head and neck
- Centrosomes, genomic instability, and cervical carcinogenesis
- Stochastic modelling of colon cancer: is there a role for genomic instability?
- Cdc42 GTPase-activating protein deficiency promotes genomic instability and premature aging-like phenotypes
- CpG methylation reduces genomic instability
- Detection of genomic instability in lung cancer tissues by random amplified polymorphic DNA analysis.
- DNA replication and genomic instability
- Increasing genomic instability during premalignant neoplastic progression revealed through high resolution array‐CGH
- Genomic instability in colorectal carcinomas: comparison of different evaluation methods and their biological significance
- Genomic instability in Down syndrome and Fanconi anemia assessed by micronucleus analysis and single-cell gel electrophoresis
- Zebrafish genomic instability mutants and cancer susceptibility
- Genomic instability and breast cancer
- Mutation at the polymerase active site of mouse DNA polymerase δ increases genomic instability and accelerates tumorigenesis
- … of the retinoblastoma tumor suppressor checkpoint during keratinocyte immortalization is not sufficient for induction of centrosome-mediated genomic instability
- The grapefruit flavanone naringin protects against the radiation-induced genomic instability in the mice bone marrow: a micronucleus study
- Haploinsufficiency of Anx7 tumor suppressor gene and consequent genomic instability promotes tumorigenesis in the Anx7 (+/-) mouse
- Genomic instability and increased expression of BUB1B and MAD2L1 genes in ductal breast carcinoma
- Fumarylacetoacetate, the metabolite accumulating in hereditary tyrosinemia, activates the ERK pathway and induces mitotic abnormalities and genomic instability
- Genomic instability: potential contributions to tumour and normal tissue response, and second tumours, after radiotherapy
- Quantitative evaluation of genomic instability as a possible predictor for development of hepatocellular carcinoma: comparison of loss of heterozygosity and replication …
- p53 Abnormalities and Genomic Instability in Primary Human Breast Carcinomas
- Genetic disorders associated with cancer predisposition and genomic instability
- The current clinical value of genomic instability
- Bystander effects in UV-induced genomic instability: antioxidants inhibit delayed mutagenesis induced by ultraviolet A and B radiation
- Reduced telomere DNA content is correlated with genomic instability and metastasis in invasive human breast carcinoma
- Could MYC induction of mitochondrial biogenesis be linked to ROS production and genomic instability?
- Genomic instability, endoreduplication, and diminished Ig class-switch recombination in B cells lacking Nbs1
- Genomic instability and metastatic progression
- Interlocus VJ recombination measures genomic instability in agriculture workers at risk for lymphoid malignancies.
- Thyroid carcinoma is characterized by genomic instability: evidence from p53 mutations
- Emerging roles of DNA tumor viruses in cell proliferation: new insights into genomic instability
- Human premature aging syndromes and genomic instability
- The loss of PIN1 deregulates cyclin E and sensitizes mouse embryo fibroblasts to genomic instability
- Genomic instability of microsatellite repeats in prostate cancer: relationship to clinicopathological variables
- Evolutionarily conserved low copy repeats (LCRs) in 22q11 mediate deletions, duplications, translocations, and genomic instability: an update and literature …
- A gain of function p53 mutant promotes both genomic instability and cell survival in a novel p53‐null mammary epithelial cell mode.
- Genomic instability: The cause and effect of BCR/ABL tyrosine kinase
- Telomeric repeats on small polydisperse circular DNA (spcDNA) and genomic instability
- RAPD‐based detection of genomic instability in soybean plants derived from somatic embryogenesis
- Radiation sensitivity and genomic instability in the hematopoietic system: Frequencies of micronucleated reticulocytes in whole‐body X‐irradiated BALB/c and C57BL …
- Viral carcinogenesis and genomic instability
- The absence of the yeast chromatin assembly factor Asf1 increases genomic instability and sister chromatid exchange
- Sparsely ionizing diagnostic and natural background radiations are likely preventing cancer and other genomic-instability-associated diseases
- Is exposure to environmental or industrial endocrine disrupting estrogen-like chemicals able to cause genomic instability?
- The human papillomavirus type 16 E6 and E7 oncoproteins cooperate to induce mitotic defects and genomic instability by uncoupling centrosome duplication from the …
- Genomic instability in chronic viral hepatitis and hepatocellular carcinoma
- Non-clonability correlates with genomic instability: a case study of a unique DNA region
- p53 protein accumulation and genomic instability in head and neck multistep tumorigenesis
- Mutation of the Drosophila homologue of the Myb protooncogene causes genomic instability
- Genomic instability due to V (D) J recombination-associated transposition
- Telomeric sequences, radiation sensitivity and genomic instability
- Genomic instability and tumor-specific alterations in oral squamous cell carcinomas assessed by inter-(simple sequence repeat) PCR
- Allelic loss and gain, but not genomic instability, as the major somatic mutation in primary hepatocellular carcinoma
- High-Resolution Analysis of Chromosomal Breakpoints and Genomic Instability Identifies PTPRD as a Candidate Tumor Suppressor Gene in Neuroblastoma
- A biological-based model that links genomic instability, bystander effects, and adaptive response
- Genomic instability in squamous cell carcinoma of the head and neck.
- Evidence for genomic instability in human colonic aberrant crypt foci.
- The death-inducing effect and genomic instability
- Genomic instability and AIDS
- High-risk but not low-risk HPV E2 proteins bind to the APC activators Cdh1 and Cdc20 and cause genomic instability
- Biomarker correlations of urinary 2, 4-D levels in foresters: genomic instability and endocrine disruption.
- Variability: the common factor linking low dose-induced genomic instability, adaptation and bystander effects
- IR-inducible clusterin gene expression: a protein with potential roles in ionizing radiation-induced adaptive responses, genomic instability, and bystander effects
- Genomic instability at exposure of low dose radiation with low LET. Mythical mechanism of unproved carcinogenic effects
- Deregulated CDC25A expression promotes mammary tumorigenesis with genomic instability
- Genomic instability in pituitary adenomas
- Increased incidence of CAD gene amplification in tumorigenic rat lines as an indicator of genomic instability of neoplastic cells
- Lens epithelial cells derived from αB‐crystallin knockout mice demonstrate hyperproliferation and genomic instability
- Cancer-specific genomic instability in bronchial lavage: a molecular tool for lung cancer detection
- Chromosomal biomarkers for detection of human papillomavirus associated genomic instability in epithelial cells of cervical cytology specimens
- Inhibition of BUB1 Results in Genomic Instability and Anchorage-independent Growth of Normal Human Fibroblasts
- Overexpression of the anaphase promoting complex/cyclosome inhibitor Emi1 leads to tetraploidy and genomic instability of p53-deficient cells
- A rapid method for detection of plant genomic instability using unanchored-microsatellite primers
- Bystander effects, adaptive response and genomic instability induced by prenatal irradiation
- Genomic instability in Chinese hamster cells after exposure to X rays or alpha particles of different mean linear energy transfer
- Sequential chromosome aberration analysis following radiotherapy—no evidence for enhanced genomic instability
- High frequency of genomic instability in Ewing family of tumors
- Genomic instability in non-neoplastic oral mucosa cells can predict risk during 4-nitroquinoline 1-oxide-induced rat tongue carcinogenesis
- Differences in genomic instability between intestinal-and diffuse-type gastric cancer
- Overexpression of the oncogenic kinase Pim-1 leads to genomic instability
- Genomic instability measurement in the diagnosis of thyroid neoplasms
- Genomic instability-based transgenic models of prostate cancer
- Increased cell proliferation is associated with genomic instability: elevated micronuclei frequencies in estradiol-treated human ovarian cancer cells
- Genomic instability of prawn white spot bacilliform virus (WSBV) and its association to virus virulence
- Increased tumor proliferation and genomic instability without decreased apoptosis in MMTV-ras mice deficient in p53
- Genomic instability in human lymphocytes irradiated with individual charged particles: Involvement of tumor necrosis factor α in irradiated cells but not bystander cells
- An anoxia inducible endonuclease and enhanced DNA breakage as contributors to genomic instability in cancer
- Chromosomal aberrations and genomic instability induced by topoisomerase-targeted antitumour drugs
- Transposon-induced hotspots for genomic instability
- Transgenerational transmission of radiation induced genomic instability
- Genomic instability: on the birth and death of cancer
- Assessment of genomic instability in breast cancer and uveal melanoma by random amplified polymorphic DNA analysis
- Loss of heterozygosity and genomic instability in synchronous endometrioid tumors of the ovary and endometrium
- Chromosome analysis in childhood cancer survivors and their offspring—no evidence for radiotherapy-induced persistent genomic instability
- Effects of hTERT on metal ion-induced genomic instability
- Correlation of levels and patterns of genomic instability with histological grading of DCIS
- High-Copy-Number Expression of Sub2p, a Member of the RNA Helicase Superfamily, Suppresses hpr1-Mediated Genomic Instability
- Intrachromosomal genomic instability in human sporadic colorectal cancer measured by genome-wide allelotyping and inter-(simple sequence repeat) PCR
- Genomic instability in sporadic colorectal cancer quantitated by inter‐simple sequence repeat PCR analysis
- Mutations of the transforming growth factor-β type II receptor gene and genomic instability in hereditary nonpolyposis colorectal cancer
- Control of Genomic Instability and Epithelial Tumor Development by the p53-Fbxw7/Cdc4 Pathway
- Hepatitis C virus core protein transforms murine fibroblasts by promoting genomic instability
- SMC3 knockdown triggers genomic instability and p53-dependent apoptosis in human and zebrafish cells
- Bystander-mediated genomic instability after high LET radiation in murine primary haemopoietic stem cells
- Induced genomic instability in irradiated germ cells and in the offspring; reconciling discrepancies among the human and animal studies
- Radiation-induced genomic instability in immortalized haemopoietic stem cells
- … lesion‐specific microsatellite alterations in premalignant and malignant neoplasia of uterine cervix: a local field effect of genomic instability and clonal evolution
- Genomic Instability of Microsatellite Repeats and Mutations of H-, K-, and N-ras, and p53 Genes in Renal Cell Carcinoma
- Genomic instability in ovarian cancer: a reassessment using an arbitrarily primed polymerase chain reaction.
- p53 tumor suppressor gene status and the degree of genomic instability in sporadic colorectal cancers
- Radiation‐induced genomic instability: A role for secreted soluble factors in communicating the radiation response to non‐irradiated cells
- Genomic instability in wheat induced by chromosome 6B (S) of Triticum speltoides.
- Analysis of genomic instability in Li-Fraumeni fibroblasts with germline p53 mutations
- Some aspects on radiation induced transmissible genomic instability
- Transgenerational transmission of radiation damage: genomic instability and congenital malformation
- Genomic instability in scleroderma
- Abnormal telomere metabolism in Fanconi’s anaemia correlates with genomic instability and the probability of developing severe aplastic anaemia
- Lethal and teratogenic effects in two successive generations of the HLG mouse strain after radiation exposure of zygotes—association with genomic instability?
- Precocious G1/S transitions and genomic instability: the origin connection
- Molecular cytogenetic analysis of genomic instability at the 1q12–22 chromosomal site in B‐cell non‐Hodgkin lymphoma
- Oxidative stress signalling: a potential mediator of tumour necrosis factor α-induced genomic instability in primary vascular endothelial cells
- Genomic instability in the offspring of irradiated parents: facts and interpretations
- Mutations in Drosophila myb lead to centrosome amplification and genomic instability
- Telomeric fusions in cultured human fibroblasts as a source of genomic instability
- Bystander effects, genomic instability, adaptive response, and cancer risk assessment for radiation and chemical exposures
- Induction of genomic instability in normal human bronchial epithelial cells by 238 Pu α-particles
- DNA mismatch repair proteins: potential guardians against genomic instability and tumorigenesis induced by ultraviolet photoproducts
- Genomic instability, bystander effects and radiation risks: implications for development of protection strategies for man and the environment.
- Aberrant expression of cell‐cycle regulator cyclin D1 in breast cancer is related to chromosomal genomic instability
- Mutant p53 and genomic instability in a transgenic mouse model of breast cancer
- Genomic instability in radiation-induced mouse lymphoma from p53 heterozygous mice
- Radiation-induced carcinogenesis: individual sensitivity and genomic instability
- Anoxia-inducible endonuclease activity as a potential basis of the genomic instability of cancer cells
- Replication errors in hematological neoplasias: genomic instability in progression of disease is different among different types of leukemia.
- G2 and spindle assembly checkpoint adaptation, and tetraploidy arrest:: Implications for intrinsic and chemically induced genomic instability
- Analysis of genomic instability using multiple assays in a patient with Rothmund–Thomson syndrome
- Delayed activation of DNA damage checkpoint and radiation-induced genomic instability
- c-MYC overexpression in Ba/F3 cells simultaneously elicits genomic instability and apoptosis
- Analysis of genomic instability in squamous cell carcinoma of the head and neck using the random amplified polymorphic DNA method
- Genomic Instability Induced by Mutations in Saccharomyces cerevisiae POL1
- Deregulated Expression of c-mos in Non-Small Cell Lung Carcinomas: Relationship with p53 Status, Genomic Instability, and Tumor Kinetics
- Unbalanced expression of licensing DNA replication factors occurs in a subset of mantle cell lymphomas with genomic instability
- Genomic instability and telomerase activity in human bronchial epithelial cells during immortalization by human papillomavirus-16 E6 and E7 genes
- Genomic instability in multistage carcinogenesis
- Bloom’s and Werner’s syndrome genes suppress hyperrecombination in yeast sgs1 mutant: Implication for genomic instability in human diseases
- Multiple pathways leading to genomic instability and tumorigenesis
- Manifestations and mechanisms of radiation-induced genomic instability in V-79 Chinese hamster cells
- Tumors of DNA mismatch repair-deficient hosts exhibit dramatic increases in genomic instability
- The ribonucleotide reductase R2 gene is a non-transcribed target of c-Myc-induced genomic instability
- APE1 overexpression in XRCC1-deficient cells complements the defective repair of oxidative single strand breaks but increases genomic instability
- Poly (ADP‐ribosyl) ation, genomic instability, and longevity
- Prognostic significance of cell cycle proteins and genomic instability in borderline, early and advanced stage ovarian carcinomas
- In memoriam Bernard Strehler—genomic instability in ageing: a persistent challenge
- Characterisation of breast fine-needle aspiration biopsies by centrosome aberrations and genomic instability
- A measure of genomic instability and its relevance to lymphomagenesis
- Genomic instability during Myc-induced lymphomagenesis in the bursa of Fabricius
- Aberrant activation of γ-catenin promotes genomic instability and oncogenic effects during tumor progression
- The role of genomic instability in the development of human cancer
- Induction of genomic instability in SV40 transformed human cells: sufficiency of the N-terminal 147 amino acids of large T antigen and role of pRB and p53.
- Impact of genomic imprinting on genomic instability and radiation-induced mutation
- Susceptibility to radiation-induced leukaemia/lymphoma is genetically separable from sensitivity to radiation-induced genomic instability
- Genomic Instability at the BUB1 Locus in Colorectal Cancer, but not in Non-Small Cell Lung Cancer1
- Genomic instability of the DYZ1 repeat in patients with Y chromosome anomalies and males exposed to natural background radiation
- Carcinogenic potential and genomic instability of beryllium sulphate in BALB/c-3T3 cells
- Alkaline single-cell gel electrophoresis (comet assay): a simple technique to show genomic instability in sporadic breast cancer
- Loss of Brca2 and p53 synergistically promotes genomic instability and deregulation of T-cell apoptosis
- First case of aplastic anemia in a Japanese child with a homozygous missense mutation in the NBS1 gene (I171V) associated with genomic instability
- Mitotic and post mitotic consequences of genomic instability induced by oncogenic Ha-Ras
- Constitutional genomic instability, chromosome aberrations in tumor cells and retinoblastoma
- Transgenerational genomic instability as revealed by a somatic mutation assay using the medaka fish
- p53 mutations, methylation and genomic instability in the progression of chronic myeloid leukaemia
- The genomic instability of yeast cdc6-1/cdc6-1 mutants involves chromosome structure and recombination
- Genomic instability of human mammary epithelial cells overexpressing a truncated form of EMSY
- Genomic instability in bone marrow failure syndromes
- Position effect variegation and genomic instability
- Radiation-induced genomic instability: manifestations and mechanisms
- Genomic instability due to germline p53 mutations drives preneoplastic progression toward cancer in human cells
- The contribution of epigenetic changes to abnormal centrosomes and genomic instability in breast cancer
- Persistent Genomic Instability in the Yeast Saccharomyces cerevisiae Induced by Ionizing Radiation and DNA-Damaging Agents
- DNA profiling analysis of 100 consecutive de novo acute myeloid leukemia cases reveals patterns of genomic instability that affect all cytogenetic risk groups
- Genomic instability and alterations in Apc, Mcc and Dcc in Hong Kong patients with colorectal carcinoma
- Ovarian cancer genomic instability correlates with p53 frameshift mutations
- Genomic instability and bystander effects: a paradigm shift in radiation biology?
- Genomic instability in rat: breakpoints induced by ionising radiation and interstitial telomeric-like sequences
- Spontaneous mutations in digestive tract of old mice show tissue-specific patterns of genomic instability
- Indirect mechanisms of genomic instability and the biological significance of mutations at tandem repeat loci
- Werner syndrome: molecular insights into the relationships between defective DNA metabolism, genomic instability, cancer and aging
- Deficiency of the Cockayne syndrome B (CSB) gene aggravates the genomic instability caused by endogenous oxidative DNA base damage in mice
- The RAG-1/2 endonuclease causes genomic instability and controls CNS complications of lymphoblastic leukemia in p53/Prkdc-deficient mice
- Evidence for a role of delayed death and genomic instability in radiation-induced neoplastic transformation of human hybrid cells
- The role of genomic instability in the pathogenesis of squamous cell carcinoma of the head and neck
- Fermentation of starch and protein in the colon: implications for genomic instability
- Genomic Instability in Gadd45a-/- Cells is Coupled with S-Phase Checkpoint Defects
- Regulation of the DNA replication fork: a way to fight genomic instability
- Genomic instability in radial growth phase melanoma cell lines after ultraviolet irradiation
- Genomic instability in mouse Burkitt lymphoma is dominated by illegitimate genetic recombinations, not point mutations
- Nucleophosmin suppresses oncogene-induced apoptosis and senescence and enhances oncogenic cooperation in cells with genomic instability
- c-Myc-associated genomic instability of the dihydrofolate reductase locus in vivo.
- Conversion of normal to malignant phenotype: telomere shortening, telomerase activation, and genomic instability during immortalization of human oral keratinocytes
- c-Myc dependent initiation of genomic instability during neoplastic transformation
- Molecular pathogenesis of thyroid cancer: the significance of oncogenes, tumor suppressor genes, and genomic instability
- Postreplicative joining of DNA double-strand breaks causes genomic instability in DNA-PKcs–deficient mouse embryonic fibroblasts
- The role of DNA repeats and associated secondary structures in genomic instability and neoplasia
- Role of transposable elements in age-related genomic instability
- Lymphocyte-specific genomic instability and risk of lymphoid malignancy
- Radiation-induced genomic instability in repair deficient mutants of Chinese hamster cells
- Constitutional Genomic Instability with Inversions, Duplications, and Amplifications in 9p23–24 in BRCA2 Mutation Carriers
- Mammalian DNA repair responses and genomic instability
- Induction of chromosome aberrations and delayed genomic instability by photochemical processes
- Genomic instability in oral squamous cell carcinoma: relationship to betel-quid chewing
- A comparison of folic acid deficiency-induced genomic instability in lymphocytes of breast cancer patients and normal non-cancer controls from a Chinese population …
- Genomic instability driven by the human T-cell leukemia virus type I (HTLV-I) oncoprotein, Tax
- Genomic instability and poor prognosis associated with abnormal TP53 in breast carcinomas. Molecular and immunohistochemical analysis
- Tracing radiation induced genomic instability in vivo in the haemopoietic cells from fetus to adult mouse
- Genomic instability in cancer development
- Bystander effect and genomic instability. Challenging the classic paradigm of radiobiology
- Protection against prenatal irradiation‐induced genomic instability and its consequences in adult mice by Ocimum flavonoids, orientin and vicenin
- Enhancement of genomic instability by 17βestradiol in minisatellite sequences of X-ray-transformed mouse 10T1/2 cells
- Genomic instability in picornaviruses
- Genomic instability and tumorigenic induction in immortalized human bronchial epithelial cells by heavy ions
- Genomic instability and cancer: scanning the Caenorhabditis elegans genome for tumor suppressors
- Absence of genomic instability in mice following prenatal low dose-rate γ-irradiation
- Genomic instability in hepatocellular carcinoma revealed by using the random amplified polymorphic DNA method
- Radiation induces genomic instability and mammary ductal dysplasia in Atm heterozygous mice
- Emerging roles of centrosomal amplification and genomic instability in cancer
- Bcr/Abl, leukemogenesis, and genomic instability: a complex partnership
- Regulation of genomic instability in preneoplastic cells.
- Gamma irradiation of Type B spermatogonia leads to heritable genomic instability in four generations of mice
- Genomic instability in both wild-type and telomerase null MEFs
- Low-level genomic instability is a feature of papillary thyroid carcinoma: an array comparative genomic hybridization study of laser capture microdissected papillary …
- Genomic instability induced by ionizing radiation
- Transmission of genomic instability from a single irradiated human chromosome to the progeny of unirradiated cells
- An evaluation of the role of LIG4 in genomic instability and adaptive mutagenesis in Candida albicans
- Sec13 induces genomic instability in U2OS cells
- c-Myc-mediated genomic instability proceeds via a megakaryocytic endomitosis pathway involving Gp1bα
- Correspondence re: D. Zimonjic et al., Derivation of Human Tumor Cells in Vitro without Widespread Genomic Instability. Cancer Res., 61: 8838–8844, 2001.
- In vitro analysis of genomic instability triggered by BRCA1 missense mutations
- Involvement of telomere dysfunction in the induction of genomic instability by radiation in scid mouse cells
- A mathematical model of radiation carcinogenesis with induction of genomic instability and cell death
- Genomic instability in cancer: biological and mathematical approaches
- Multiple manifestations of X‐ray–induced genomic instability in Chinese hamster ovary (CHO) cells
- Characterization of genomic instability in ulcerative colitis neoplasia leads to discovery of putative tumor suppressor regions
- Genomic instability in colorectal cancers in Turkey
- Coming of age:’dysgenetics’-a theory connecting induction of persistent delayed genomic instability with disturbed cellular ageing
- Bcl-2 over-expression promotes genomic instability by inhibiting apoptosis of cells exposed to hydrogen peroxide
- Cyclooxygenase-2 expression induces genomic instability in MCF10A breast epithelial cells
- Non-Targeted Radiation Effects in Radiotherapy &Roles of Radiation-Induced Genomic Instability and of the Bystander Effect in Cancer Cure by Radiotherapy
- The genomic instability associated with integrated simian virus 40 DNA is dependent on the origin of replication and early control region
- Genomic instability analysis of urine sediment versus tumor tissue in transitional cell carcinoma of the urinary bladder
- The breast cancer susceptibility allele CHEK2* 1100delC promotes genomic instability in a knock-in mouse model
- Spontaneous and radiation-induced genomic instability in human cell lines differing in cellular TP53 status
- N-MYC oncogene amplification: a consequence of genomic instability in human neuroblastoma
- Genomic instability in precancerous lesions before inactivation of tumor suppressors p53 and APC in patients
- Genomic instability and target gene mutations in colon cancers with different degrees of allelic shifts
- Genomic instability is associated with lack of telomerase activation in ovarian cancer
- Persistent oxidative stress and gene expression changes in radiation-induced genomic instability
- Radiation-induced genomic instability and bystander effects: implications for radiation protection
- Patterns of genotoxicity and contaminant exposure: Evidence of genomic instability in the marsh frogs (rana ridibunda) of sumgayit, azerbaijan
- Genomic instability in the bank vole: population-ecological aspects
- The problem of induced genomic instability in the child body cells under conditions of long-term effect of small radiation doses
- … hepatitis B virus genome binds to members of the HMG domain protein family and the Y box binding protein family; implication of these proteins in genomic instability
- Telomere Higher‐Order Structure and Genomic Instability
- Vincristine increases the genomic instability in irradiated cultured human peripheral blood lymphocytes
- A mutation in the centriole-associated protein centrin causes genomic instability via increased chromosome loss in Chlamydomonas reinhardtii
- Molecular prognosticators and genomic instability in papillary thyroid cancer
- Genomic instability and mobile genetic elements in regions surrounding two discoidin I genes of Dictyostelium discoideum
- Cis-acting transmission of genomic instability
- DNA repair genes and genomic instability in severe male factor infertility
- Association of p53 genomic instability with the glutathione S-transferase null genotype in gastric cancer in the Portuguese population.
- Fluorescence in situ hybridization analysis of hobo, mdg1 and Dm412 transposable elements reveals genomic instability following the Drosophila …
- Measurement of Genomic Instability in Preleukemic P190BCR/ABL Transgenic Mice Using Inter-Simple Sequence Repeat Polymerase Chain Reaction
- Uncoupling of genomic instability and tumorigenesis in a mouse model of Burkitt’s lymphoma expressing a conditional box II-deleted Myc protein
- Induction of Genomic Instability in TK6 Human Lymphoblasts Exposed to 137Cs γ Radiation: Comparison to the Induction by Exposure to Accelerated 56Fe Particles
- Genomic instability in basal cell carcinomas
- In utero exposure to diethylstilbestrol (DES) does not increase genomic instability in normal or neoplastic breast epithelium
- Retracted: Impact of genomic instability in risk assessment and chemoprevention of oral premalignancies
- Chromosome division figures reveal genomic instability in tumorigenesis of human colon mucosa
- New Research on Genomic Instability
- The medaka as a model for studying germ-cell mutagenesis and genomic instability
- Genomic instability and tissue expression of angiogenic growth factors in sporadic colorectal cancer
- aCGH local copy number aberrations associated with overall copy number genomic instability in colorectal cancer: coordinate involvement of the regions including …
- Rarity of genomic instability in pathogenesis of systemic anaplastic large cell lymphoma (ALCL) in immunocompetent patients
- Genomic instability and radiation mutagenesis
- Genomic instability in head and neck cancer
- ENU administration causes genomic instability along with single nucleotide polymorphisms in p53 during gliomagenesis: T11TS administration demonstrated in vivo …
- Molecular characterization of a cryptic wheat-Thinopyrum intermedium translocation line: evidence for genomic instability in nascent allopolyploid and …
- Widespread bimodal intrachromosomal genomic instability in sporadic breast cancers associated with 13q allelic imbalance
- Genomic instability in silica-and cadmium chloride-transformed BALB/c-3T3 and tumor cell lines by random amplified polymorphic DNA analysis
- Papillary thyroid cancer: High inter‐(simple sequence repeat) genomic instability in a typically indolent cancer
- Genomic instability, bystander effect, cytoplasmic irradiation and other phenomena that may achieve fame without fortune.
- Genomic instability after exposure to radiation at low doses (in the 10-kilometer zone of the accident at the Chernobyl Atomic Electric Power Station and under …
- Genomic instability of human aberrant crypt foci measured by inter-(simple sequence repeat) PCR and array-CGH
- Lethal sectoring, genomic instability, and delayed division delay in HeLa S3 cells surviving alpha-or X-irradiation
- Genomic instability involved in virus-related hepatocarcinogenesis
- p53 loss of function enhances genomic instability and accelerates clonal evolution of murine myeloid progenitors expressing the p (210) BCR-ABL tyrosine kinase
- Expression of Cyclins A, E and Topoisomerase II α correlates with centrosome amplification and genomic instability and influences the reliability of cytometric …
- Genetic rearrangements beget genomic instability
- Telomeres, genomic instability, DNA repair and Breast Cancer
- Architecture of Burkholderia cepacia complex σ70 gene family: evidence of alternative primary and clade-specific factors, and genomic instability
- Identification of additional complementation groups that regulate genomic instability
- Genomic instability on hMSH2, hMLH1, CD48 and IRF4 loci in pulmonary sarcoidosis
- Implications of delayed reproductive cell death (lethal mutations/genomic instability) for the interpretation of tissue responses
- Frequent HPRT mutations in paroxysmal nocturnal haemoglobinuria reflect T cell clonal expansion, not genomic instability
- Replication status as a possible marker for genomic instability in cells originating from genotypes with balanced rearrangements
- Design, spectrum measurements and simulations for a 238Pu α-particle irradiator for bystander effect and genomic instability experiments
- Characteristics of Genomic Instability in Clones of TK6 Human Lymphoblasts Surviving Exposure to 56Fe Ions
- Genomic instability associated with human LINE-1 retrotransposition
- Update of genetics in colorectal carcinomas: genomic instability and somatic evolution.
- Genomic instability in a PARP-1−/− cell line expressing PARP-1 DNA-binding domain
- Correlations of centrosome abnormality and genomic instability to tumor
- Mosaic eyes, genomic instability mutants, and cancer susceptibility
- Expression ofRap 1 suppresses genomic instability ofH-ras transformed mouse fibroblasts
- Genomic Instability: Signaling Pathways Orchestrating the Responsesto Ionizing Radiation and Cisplatin
- Progression elevated gene‐3, PEG‐3, induces genomic instability in rodent and human tumor cells
- Germline genomic instability in PCNA mutants of Drosophila: DNA fingerprinting and microsatellite analysis
- Genomic instability in invasive breast carcinoma measured by inter-Simple Sequence Repeat PCR
- Genomic instability of murine hepatocellular carcinomas with low and high metastatic capacities
- Lack of specificity of chromosome breaks resulting from radiation-induced genomic instability in Chinese hamster cells
- Genomic instability in drug-resistant human melanoma cell lines detected by Alu-I-arbitrary-primed PCR.
- DNA repair and genomic instability in tobacco induced malignancies of the lung and upper aerodigestive tract
- Determination of genomic damage in neuroblastic tumors by arbitrarily primed PCR: MYCN amplification as a marker for genomic instability in neuroblastomas
- Genomic instability in human lymphoid cells exposed to 1 GeV/amu Fe ions.
- Demonstration by DNA fingerprint analysis of genomic instability in mouse BALB 3T3 cells during cell transformation
- Genomic instability and the development of metastatic lymph node tumors
- Allelic losses at genomic instability-associated loci in villous adenomas and adjacent colorectal cancers
- SV40 recombinants carrying ad (CT· GA) 22 sequence show increased genomic instability
- Genomic Instability and Loh at 2 Polymorphic Sites in the H-Ras1 Gene
- Neoplastic progression in Barrett’s esophagus: Genomic instability, cell cycle abnormalities, and clonal evolution
- Genomic instability in B-cells and diversity of recombinations that activate c-myc
- MYC-Induced Cyclin D2 Genomic Instability in Murine B Cell Neoplasms
- Non-homologous recombination between Alu and LINE-1 repeats caused a 430-kb deletion in the dystrophin gene: a novel source of genomic instability
- Genomic instability and male infertility
- Genomic instability in the progression of sporadic nasopharyngeal carcinoma
- c-Myc deregulation promotes a complex network of genomic instability
- Induced germ line genomic instability at mini-and micro-satellites in animals
- The influence of DNA methylation on topoisomerase II activity and its possible link with genomic instability in different cell lines of the Syrian hamster
- Clastogenic Factors, Bystander Effects and Genomic Instability In Vivo
- Genomic instability associated with limb defects: case report and review of the literature.
- Genomic stability and instability: a working paradigm
- Genomic instability in uranium miners after high radiation exposures
- Rarity of microsatellite genomic instability in B‐cell non‐Hodgkin’s lymphomas in hepatitis C virus‐infected patients
- Induction of stem cell cycling in mice increases their sensitivity to a chemical leukaemogen: implications for inherited genomic instability and the bystander effect
- Genomic heterogeneity and instability in colorectal cancer: spectral karyotyping, glutathione transferase-Ml and ras
- US‐Japan Seminar on “Genomic Instability during Carcinogenesis and Tumor Progression”
- Genomic instability induced by AZT in cultured normal human mammary epithelial cells (NHMECs) generates aneuploidy
- Towards resolving conflicting reports of radiation-induced genomic instability in populations exposed to ionizing radiation: Implications for the hibakusha
- Genomic instability and breast cancer progression
- Cytogenetic signs of genomic instability in Alzheimer’s disease.
- Genomic instability, as measured by microsatellite alterations, is not associated with liver tumor development in the genetically susceptible B6C3F1 mouse
- Investigation of genomic instability in paediatric Barrett’s oesophagus using laser microdissection on paraffin-embedded endoscopic biopsies
- Is delayed genomic instability specifically induced by high-LET particles?
- Radiation-induced genomic instability in tandem repeat sequences is not predictive of unique sequence instability
- Genomic instability associated with myotonic dystrophy does not involve p53 expression and activity
- Radioadaptive response and genomic instability: a phenotypic dichotomy of genome–environment interaction
- Genomic mechanisms and measurement of structural and numerical instability in cancer cells
- The contribution of communication between irradiated cells and between bystander cells to clonogenic survival and genomic instability
- Decoupling of normal CD40/interleukin-4 immunoglobulin heavy chain switch signal leads to genomic instability in SGH-MM5 and RPMI 8226 multiple myeloma cell …
- 18 Niacin Status, Poly (ADP-ribose) Metabolism and Genomic Instability
- Non-homologous end-joining genes are not inactivated in human radiation-induced sarcomas with genomic instability
- Genomic instability, susceptibility genes, and carcinogenesis
- Genomic instability at the human CD5 gene promoter
- Estrogen Receptor-mediated Genomic Instability in the Syrian Hamster Kidney: A Critical Event in Hormonal Oncogenesis
- Possible mechanisms of ionizing radiation-induced genomic instability
- Genetic predisposition and genomic instability: Studies with mouse embryos
- Random Amplified DNA Disclosed Genomic Instability in Successive Cutting-Propagated Clones of Sweet Potato (Ipomoea Batatas (L) Lam.) with N-Fertilizer …
- Genomic instability and colorectal cancer
- Telomerase as a potential anticancer target: growth inhibition and genomic instability
- Genomic instability after low level irradiation in the zone of Chernobyl disaster and in laboratory conditions
- [22] Gene amplification as marker for studying genomic instability
- The absence of the facts connected with the genomic instability after the irradiation in low doses by radiation with low LET
- Crystalline nickel sulfide-induced genomic instability in transformed human broncho-epithelial cells
- Genomic instability of the APC gene found in glioblastoma
- Analysis of genomic instability by fluorescence DNA sequencer
- Models for stuyding genomic instability during aging
- Genomic Instability, DNA Alterations and Tumor Eosinophilic Expression in Head and Neck Squamous Cell Carcinoma
- In vitro analysis of cultured Barrett’s esophagus cells: insights into mechanisms of genomic instability and possible therapeutic strategies
- Conditional coalescent trees with two mutation rates and their application to genomic instability
- Radiation-induced genomic instability in haemopoietic cells
- The Role of Telomeres in Genomic Instability
- Mitotic instability associated with late genomic changes in bone and soft tissue tumours
- BCR/ABL Kinase Disrupts Formation of Mismatch Repair Complex To Induce Genomic Instability.
- Genomic Instability in Fanconi Anaemia and Nijmegen Breakage Syndrome
- Low dose studies with focused X-rays in cell and tissue models: mechanisms of bystander and genomic instability responses
- Age-induced genomic instability in budding yeast.
- Genomic instability analysis in hereditary cancer syndrome
- Indirect mechanisms of radiation induced genomic instability at repeat loci
- Genomic instability in human premature aging
- Plant genomic instability detected by microsatellite-primers
- Comparative genomic hybridisation divides retinoblastomas into a high and a low level chromosomal instability group
- Response to comment on” Chromosomal instability and tumors promoted by DNA hypomethylation” and” induction of tumors in mice by genomic hypomethylation”
- Telomere shortening and genomic instability: primary cells from patients with telomere repair complex mutations are susceptible to end-to-end chromosome fusion …
- The role of cyclin E in cell cycle regulation and genomic instability
- Analysis of genomic instability in bronchial cells from uranium miners
- Mutation of p53 gene and genomic instability in testicular tumors
- Genomic instability and radiation effects
- Genomic instability in the progression of chronic myelogenous leukemia to blast crisis by PCR-microsatellite instability assay (MIA)
- Genomic Instability in Sporadic Colorectal Cancer: A Destabilized Genome Producing Accelerated Cellular Evolution as the Fundamental Nature of Cancer
- Genomic instability following irradiation
- Molecular Characterization of a Prototype Family Harboring Two Genomic Instability Disorders: Ataxia Telangiectasia and Fanconi Anemia.
- Promoter Shuffling by Sequential Genomic Rearrangements in Follicular Lymphoma Reveals an Ongoing Genomic Instability at the BCL6 Locus.
- Telomere Dysfunction Increases Mutation Rate and Genomic Instability
- Detection of genomic instability in offspring of male mice chronically exposed to gamma-radiation by the” adaptive response” test
- Aberrant genes expression, genomic instability and increased cell proliferation of mouse testicular Leydig cells by sodium arsenite: a possible mechanism for arsenic …
- Development of genomic instability after irradiation
- Non B-DNA structures and genomic instability associated with myotonic dystrophy type 2 (CCTG)•(CAGG) repeats
- … of FLT3 induces increased ROS production, DNA damage and misrepair: implications for RAC1-STAT5 function in genomic instability in myeloid malignancies
- Genomic instability switch identified
- Internal Tandem Duplications of FLT3 Induces Increased ROS Production, DNA Damage and Misrepair: Implications for Genomic Instability and Disease Resistance …
- Genomic instability in interspecific cell hybrids III. Repression of Colcemid resistance in hybrids suggests preferential β-tubulin expression
- Mechanism of Genomic Instability and Its Clinical Applications.
- Radiation-induced genomic instability
- Prostate Cancer Models of Genomic Instability
- DNA damage and genomic instability
- Radiation induced genomic instability
- … Strand Annealing (SSA), the Rare and Extremely Unfaithful DNA Double-Strand Break Repair Pathway To Facilitate Genomic Instability in Hematologic Malignancies.
- Role of genomic instability in breast cancer
- Genomic Instability and DNA Repair
- Genomic instability cytogenetic indicators; Indicadores citogeneticos de inestabilidad genomica
- Radiation-induced Genomic Instability
- Genomic instability in nasopharyngeal carcinoma
- Alpha-particles radiation and genomic instability
- Evaluation of genomic instability and cancer prevention
- Genomic instability in colorectal carcinoma
- The Mouse Genomic Instability Mutation
- Origin of genomic instability induced by ionizing radiation
- Alpha-particles radiation and genomic instability
- Evaluation of adult papillary thyroid carcinomas by comparative genomic hybridization and microsatellite instability analysis
- Spontaneous genomic instability in humans
- Induced radiation genomic instability; Indutsirovannaya radiatsiej nestabil’nost’genoma
- Genomic instability. New insight into the health effects of radiation; Perimaen epaevakaisuus. Uusi naekoekulma saeteilyn terveysvaikutuksiin
- The role of radiation types and dose in induced genomic instability
- Induced radiation genomic instability
- Genomic instability in chronic myelogenous leukemia
- Genetic Predisposition to Genomic Instability in Cancer
- Autophagy and genomic instability
- Genomic instability links diet to cancer
- The interplay of genomic instability and transformation in carcinogenesis
- Evaluation of Genomic Instability in the Abnormal Prostate
- HRAD51 Involvement in Genomic Instability and Development of Breast Cancer
- Evaluation of Genomic Instability in the Abnormal Prostate
- Characterizing regions associated with genomic instability in colon cancer
- Genomic instability: Environmental invasion and the enemies within
- GENOMIC INSTABILITY IN SPORADIC COLORECTAL CANCER
- Measuring the amount of genomic instability during early development of Human tumors
- Genomic instability and neurodegenerative disease
- Genomic instability is not described by aneuploidy
- Genomic instability and mismatch repair mechanism
- Genetic Predisposition to Genomic Instability in Cancer (Volume 1)
- Genomic Instability and Yeast Aging
- The genomic instability induced by {sup 60} Co {gamma} ray radiation
- Patterns of genomic instability differentiate clinical outcomes in patients with invasive breast cancer
- Genomic Instability Induced by Low Dose Irradiation
- Induced gamete genomic instability on mini-and microsatellite sequences in animals
- Role of polymerase? in DNA metabolism and genomic instability
- Genomic instability in primary haemopoietic cells induced by ionizing radiation
- An analysis of genomic instability in osteosarcoma
- PTTG induces genomic instability in thyroid cells
- Genomic instability in sporadic colorectal cancer
- In situ quantification of genomic instability in breast cancer progression
- Genomic instability induced by variation in the DNA methylation pattern
- In situ quantification of genomic instability in breast cancer progression
- Genomic instability happens early in sporadic colorectal cancer
- Deregulation of cyclin E and genomic instability
- Investigation of microRNAs on genomic instability regions in breast cancer
- Tumor progression, metastatic potential and genomic instability
- The regulation of homologous recombination and its contribution to genomic instability
- Genomic instability after low level irradiation
- Differentiation and Genomic Instability in a Human Mammary Cell Model
- Delayed Genomic Instability in Bystander Cells
- The role of genomic instability and mutation hypersensitivity in tumor development
- TNF-{alpha}-induced genomic instability in primary vascular endothelial cells
- Mitochondrial dysfunction may perpetuate radiation induced genomic instability
- Mathematical Implication for Radiation Carcinogenesis based on Hypothesis of Induction of Genomic Instability
- Biochemistry of mismatch recognition and its relevance to genomic instability
- The Ha-ras oncogene: mechanisms of transformation and genomic instability
- Persistence of the genomic instability in the adult hemopoetic cells after fetal irradiation of mouse
- Radiation-induced genomic instability, and the cloning and functional analysis of its related gene
- Colon Cancer at Molecular Level: Genomic Instability in the Pathogenesis of Colorectal Cancer
- Ionizing radiation induced genomic instability and its relation to radiation carcinogenesis
- Study of genomic instability of CHL cells induced by different dose of gamma ray
- Radiation-induced genomic instability and delayed activation of p53
- Characterization of genomic instability in neoplastic progression of ulcerative colitis
- The Visualization, Quantification and Modeling of Genomic Instability in the Mouse and in Cultured Cells
- Genomic Instability in Transformed 16HBE Cells Induced by Nickel Acetate
- Genomic instability due to telomere insufficiencies
- HER2 gene amplification is a marker for global genomic instability
- Chromosome segregational defects: their origin, fate and contribution to genomic instability
- A positive selection assay for genomic instability
- Detection of genomic instability in normal human bronchial epithelial cells exposed to {sup 238} Pu
- Analysis of mouse models of genomic instability and cancer predisposition
- The problems of heritability of radiation-induced genomic instability; Problemy nasledovaniya radiatsionno-indutsirovannoj nestabil’nosti genoma
- Molecular mechanisms of radiation-induced genomic instability in human cells
- Mechanism of genomic instability in Prelamin A based premature ageing
- Genetics of osteosarcoma: a model of human cancer genomic instability
- Genomic instability—a story of repair, cancer and evolution with existential impact on the individual
- Inherited Disorders of Genomic Instability and Cancer Susceptibility
- Telomere dysfunction and mechanisms of genomic instability
- Prenatal irradiation induced genomic instability and its expression in adult mice
- Cytogenetic and molecular investigations of genomic instability related to human cellular aging
- The problems of heritability of radiation-induced genomic instability
- GENOMIC INSTABILITY CAUSED BY CHROMIUM AND VANADIUM IONS IN VITRO
- Genomic instability induced by {sup 60} Co {gamma} ray radiation in normal human liver cells
- The onset of genomic instability in sporadic colorectal polyps
- Telomerase activity in cells with arsenic-induced genomic instability
- Ionizing radiation induced genomic instability and bystander effects
- Induction of Genomic Instability In Vivo by Low Doses of 137Cs gamma rays
- Delayed manifestation of DNA damage and genomic instability caused by radiation-induced large deletion
- Genomic instability in a Bcr-abl leukemia mouse model
- Visualizing genomic instability: In situ detection and quantification of mutation in mice.
- Retrotransposable activation of Alu elements, genomic instability and carcinogenesis
- Genomic instability and the changes of K-ras and 15 gene in transformed 15HBE cells nickel sulfate.
- Correlation between radio-therapeutic efficacy and telomeric fusion-induced genomic instability
- Significance of genetic predisposition and genomic instability for individual sensitivity to radiation. Implications for radiation protection
- Genomic instability and accelerated cellular senescence inlaminopathy-based premature
- Genomic instability in non-functioning pituitary adenomas
- Radiation-induced genomic instability and bystander effects
- DNA repair and genomic instability in yeast aging
- Telomere dysfunction in cells with arsenic-induced genomic instability
- Genomic instability in F1 mice born to irradiated spermatozoa and p53 dependent genomic cross-talk
- The problem of induced genomic instability in the child organism under conditions of long-term effect of small radiation doses; Problema indutsirovannoj genomnoj …
- Long Interspersed Nuclear Element (LINE) Mediated Genomic Instability
- Radiation-Induced Genomic Instability in the Offspring of Irradiated Parents
- Loss of Nucleotide Excision Repair as a Source of Genomic Instability in Breast Cancer
- Expression of genomic instability in lymphocytes from children living under conditions of long term exposure to radioactive factors
- Genomic instability induced by 60Co γ ray radiation in normal human liver cells
- Genomic Instability and Epigenetic Alteration in Colorectal Carcinogenesis
- Zebrafish genomic instability mutants and cancer susceptibility, pp. 585–600
- Genomic instability induced by {sup 137} Cs {gamma}-ray irradiation in CHL surviving cells
- Constitutional genomic instability of 9p23-24 in BRCA2 mutation carriers
- Anatomy of a pericentric inversion and other instances of genomic instability
- Mechanisms of apoptosis modulation and their contribution to genomic instability in tumor cells
- Chromosomal aberrations and genomic instability after X-ray and {alpha} irradiation; Chromosomenaberrationen und genomische Instabilitaet nach Roentgen-und …
- THE PHENOMENON OF GENOMIC INSTABILITY IN THE CHILD’S BODY EXPOSED TO PROLONGED RADIATION AT SMALL DOSES AND HEALTH STATE
- Genetic predisposition and genomic instability in murine stem cells exposed to low LET radiation
- Multi-target model for carcinogenesis incorporating the genomic instability hypothesis
- Telomerase activity and genomic instability in colorectal cancers
- Genomic Instability at Premalignant and Early Stages of Breast Cancer Development.
- Crystalline nickel sulfide-induced genomic instability in transformed human broncho-epithelial cells
- The induction of genomic instability in related human lymphoblasts following exposure to Cs gamma radiation vs accelerated {sup 56} Fe Ions
- Genomic instability, deregulation of apoptosis and treatment responsiveness in sporadic colorectal cancer
- p53-mediated apoptosis and genomic instability syndromes
- Testing the Genomic Instability During the Haploid Life Cycle
- Testing the Genomic Instability During the Haploid Life Cycle
- Radiation-induced genomic instability driven by de novo chromosomal rearrangement hot spots
- Quantitative three-dimensional microscopy approaches with applications in breast cancer biology including measurement of genomic instability
- Radiation-induced genomic instability: Delayed mutagenic and cytogenetic effects
- Genomic instability in cancer: the role of the mitotic spindle checkpoint gene hBUB1
- A mathematical multistage model for radiation carcinogenesis accounting for induced genomic instability and cell death
- Genomic instability in an excision repair mutant of drosophila melanogaster
- Telomere mediated genomic instability correlates with the clinico-pathological parameters of breast cancer
- Genomic instability of intrachromosomal telomere repeat sequences
- Tailed’-nuclei as a possible express-indicator of radiation-induced genomic instability
- Genomic instability induced by 137Cs γ-ray irradiation in CHL surviving cells
- The role of free radicals and stress signalling in persistent genomic instability induced by long wavelength UV light
- Characterization of inter-(simple sequence repeat) genomic instability in sporadic colorectal cancer
- Elevated ROS production is closely associated with radiation-induced genomic instability in cultured human cells
- Genomic instability as assessed by micro satellite analysis in childhood rhabdomyosarcoma (RMS)
- Tumor Necrosis Factor-Mediated Inflammation Exacerbates Genomic Instability and Promotes Leukemia Development.
- Induction of genomic instability and mitotic dysregulation in immortalized nasopharyngeal epithelial cells
- Radiation-induced genomic instability triggered by telomere dysfunction
- Regions of genomic instability are potential resources for studies of miRNA function as well as the discovery of novel microRNAs
- Cellular protein (s) related to genomic instability in HBV-induced hepatocarcinogenesis.
- Genomic instability in children born from the Chernobyl accident victims
- Studies on ultraviolet radiation induced carcinogenesis and genomic instability using human epithelial cell lines
- Analysis of genomic instability by microsatellite analysis in childhood Burkitt’s and large cell diffuse lymphoma
- The role of cyclin D1 in cell cycle control, tumorigenesis, and genomic instability
- DNA Damage and Genomic Instability Induced by Inappropriate DNA Re-replication
- X-ray-induced genomic instability in Atm knock-out mouse cells
- Persistent genomic instability by arsenic exposure in V79 Chinese hamster cells
- Outer breast quadrants demonstrate increased patterns of DNA genomic instability
- Molecular Basis of Genomic Instability and Progression in Multiple Myeloma: Potential Role of Apurinic (Apyrimidinic) Endonuclease.
- Genomic instability in mammalian cell hybrids. IV. Is mutation frequency elevated in hybrid cells?
- Lethal Sectoring, Genomic Instability, and Delayed Division Delay in HeLa S3 Cells Surviving Alpha-or X-irradiation
- Intratumoral genetic heterogeneity in sporadic colorectal cancer and its association with underlying genomic instability
- Detection of high-level copy number changes in oral lesions suggests genomic instability at the premalignant stage
- Induction of Genomic Instability During Transformation of Human Cells with SV40 Large T Antigen
- Fetal irradiation induced genomic instability is expressed as chromosomal aneuploidy in adult mouse
- Telomere Structure and Function Provides Insights into the Generation of Genomic Instability and Carcinogenesis
- Transgenerational radiation genetics: a feasibility study for the use of the Japanese Medaka to investigate adaptive responses and genomic instability
- Genomic instability was frequently seen and was associated with Epstein-Barr Virus (EBV) gene expression in nasopharyngeal carcinoma (NPC)
- Stochastic models of the bystander effect and of transmissible genomic instability: implications for mechanisms and low dose risks
- Genomic instability in normal human fibroblasts for chronically low-dose radiation in heavy-ion radiation field
- Enhanced chemotherapeutic efficacy of paclitaxel by telomeric fusion-induced genomic instability
- Analysis of chemical species of long-lived radicals generated by ion beam radiation to mammalian cells and relationship with genomic instability
- Polymorphisms In BRCA2 And WRN, Genomic Instability And Benzene Hematotoxicity
- Detection of genomic instability in descendants of male mice exposed to chronic low-level gamma-radiation using the test’adaptive response’
- The influence of elevated endogenous free radical production on apoptosis and genomic instability in transgenic growth hormone mice
- Detection of genomic instability in {alpha}-irradiated and bystander human fibroblasts
- Symposium Address: Hormones, Centrosomes, and Genomic Instability in Mammary Carcinogenesis
- Ewing sarcomas-characterization by high resolution CGH array reveals distinct genomic instability patterns
- Segmental duplications promote genomic instability in human chromosome 15q11-q13
- Studies in mammalian ribosomal DNA: Functional genes and curious descendents of genomic instability.
- Symposia: DNA Damage Response and Genetic Instability; Genomic instability caused by the defect of chromosomal replication initiation replication
- … hybridization of osteosarcomas reveals genomic profiles indicative of breakage-fusion-bridge mechanisms and implicates RECQL4 as a marker for genomic instability …
- Lens epithelial cells derived from B-crystallin knockout mice demonstrate hyperproliferation and genomic instability
- Centrosome alterations and genomic instability during the development of Barrett’s esophagus and associated adenocarcinoma
- c-Myc-induced genomic instability: characterization of c-Myc-induced extrachromosomal elements
- Genomic Instability Induced by Two Chemical Carcinogens, Cadmium and Nickel and by Particulate Titanium Debris from an Implant
- Genomic instability induced by DNA ligase I overexpression in budding yeast
- Cancer: Cell Structures, Carcinogens and Genomic Instability/Ed. Leon P. Bignold.-Basel; Boston; Berlin: Birkhauser Verlag, 2006.-375 p.
- FANCG knockout CHO cells display sensitivity to diverse DNA damaging agents and possible genomic instability
- DNA Damage Response and Genetic Instability; A Novel Function for HSF1-Induced Mitotic Exit Failure and Genomic Instability through Direct Interaction between …
- Lethal Sectoring, genomic instability and cell cycle variation of HeLa S3 cells survived after alpha-and X-ray irradiation
- High-LET-Induced Long Lived Radicals (LLR) May Initiate Genomic Instability (TGI): Effects of Certain Antioxidants
- The Adaptive Response in p53 Cancer Prone Mice: Loss of heterozygosity and Genomic Instability
- c-Myc dependent genomic instability of the ribonucleotide reductase R2 gene
- 7.340 Avoiding Genomic Instability: DNA Replication, the Cell Cycle, and Cancer, Fall 2006
- Increased DNA Damage and Error-Prone Repair in MPD/MDS Mice with Disease Progression: Key Indicators for Increased Genomic Instability.
- Genomic instability induced by mutations in Saccharomyces cerevisiae DNA polymerase alpha
- Development of An Assay System to Detect Genomic Instability in Human Cells Bearing Partially Duplicated HPRT Gene
- NORMAL HUMAN MAMMARY EPITHELIAL CELLS SPONTANEOSLY EMERGE FROM SENESCENCE AND ACQUIRE GENOMIC INSTABILITY
- Homologous recombination in mammalian somatic cells: DNA repair, genomic instability and cancer
- Multiple Myeloma (MM) Is Characterized by Genomic Instability Regardless of Ploidy Categories and Degree of Karyotypic Complexity Is an Important Prognostic …
- The expression of γ‐glutamyltransferase in cancer cells is a factor in genomic instability, progression and drug resistance
- Molecular Basis of Genomic Instability in Breast Cancer: Regulation of the Centrosome Duplication Cycle
- The Adaptive Response in p53 Cancer Prone Mice: Loss of heterozygosity and Genomic Instability
- The Roles of Chromosome Breaks and Telomere Dynamics in the Genomic Instability Associated With Human Breast Cancer.
- Molecular epidemiological studies on the significance of oncogenes, tumor suppressor genes, and genomic instability in colorectal carcinomas among Hong Kong …
- … : DNA Damage Response and Genetic Instability; AIMP3 Haploinsufficiency inhibit p53 activation by oncogene including Ras and c-myc, result to Genomic instability
- Genomic instability, cancer predisposition and premature aging in a mouse model of Rothmund-Thomson Syndrome
- Genomic instability induced by γ-ray irradiation analyzed by cytokinesis-block MN assay in CHL cell line
- Genomic instability in a knock-in mouse model of the breast cancer susceptibility allele CHEK2*1100delC
- Investigations into genomic instability of endogenous and transfected hprt genes in mouse and human tumour cells.
- Transforming Growth Factor β1 Suppresses Genomic Instability Independent of a G1 Arrest, p53, and Rb (Cancer Research (1996) 56 (16)(3645-3650))
- Genomic instability by mutant p53 leading to allelic loss and translocation via illegitimate recombination
- X-irradiation to Spermatozoa Executes Delayed Apoptosis, Genomic Instability and Altered Development at Peri-Implantation Stage Mouse Embryos
- X-irradiation to Spermatozoa Executes Delayed Apoptosis, Genomic Instability and Altered Development at Peri-Implantation Stage Mouse Embryos
- Stochastic carcinogenesis model allowing for genomic instability fitted to SEER colon cancer data, and comparisons with patterns of risk in Japanese A-bomb survivor …
- Genomic instability in mutation induction on normal human fibroblasts irradiated with chronic low-dose radiations in heavy-ion radiation field
- ROS, DNA damage and error-prone repair: A model for genomic instability in mice with myeloid leukaemia disease progression
- Genomic Instability in Multiple Myeloma: Inducible Transfectants Provide a Model To Define the Role of RHAMM and Centrosome/Mitotic Spindle Stability in …
- RET oncogene amplification in thyroid cancer: Correlations with radiation-associated, high-grade malignancy, and genomic instability
- DNA Damage Response and Genetic Instability; AIMP3 Haploinsufficiency inhibit p53 activation by oncogene including Ras and c-myc, result to Genomic instability
- … of residents of high background radiation area (HBTA) in the southern China occur as well as radiation-induced genomic instability by telomere dysfunction
- Mitochondrial dysfunction leads to telomere shortening, apoptosis and genomic instability: Toward a unified theory of reproductive aging
- Genomic instability and tumor progression: a cytochemical, molecular biological and cytogenetic study of human tissue from uterine cervix, colon, breast and …
- Investigation of genomic instability by analysis of AP-PCR DNA fingerprints in the offspring of male mice exposed to chronic low doses of gamma-radiation; …
- Free communications: Association of p53 genomic instability with glutathione S-transferase: null: genotype in gastric cancer in the Portuguese population
- Correspondence re: G. Anderson et al., Intrachromosomal Genomic Instability in Human Sporadic Colorectal Cancer Measured by Genome-Wide Allelotyping and Inter-(Simple …
- The Role of hCDC 4 as a Tumor Suppressor Gene in Genomic Instability Underlying Prostate Cancer
- Protein tyrosine phosphatase inhibitor-induced AKT activation overrides cell cycle checkpoints, potentially leading to genomic instability
- P226: Cyclooxygenase-2 expression induces genomic instability in MCF10A breast epithelial cells
- Analysis chemical species of long-lived radicals generated by ion beam radiation to mammalian cells and relationship with mutation and genomic instability
- Investigating the Role of Nuclear Clusterin (nCLU) in Lethality and Genomic Instability in Paclitaxel (taxol)-treated Human Breast Cancer Cells
- A model of genomic instability: Diploid and tetraploid p53 knock-out mouse skin keratinocytes, growth in soft agar and in mouse xenografts.
- Transgenerational radiation genetics: The use of the Japanese Medaka (Oryzias latipes) to investigate adaptive response and genomic instability
- … parameters in aberrant crypt foci evaluation in colon carcinogenesis (glutathione S-transferases, B-RAF mutation, genomic instability, single nucleotide polymorphism …
- GENOMIC INSTABILITY AND TRANSCRIPTIONAL MODULATION ASSOCIATED WITH A TRANSFECTED TK GENE INSERTED INTO MOUSE SATELLITE DATA …
- Genomic Instability Study on the Japanese Familial Ovarian Cancer without Germline Mutation of BRCA1 or BRCA2 by Loss of Heterozygosity Analysis
- Superoxide Dismutase 2 Deficient Mice: The Role of Increased Reactive Oxygen Species in Genomic Instability
- Kaposi (KS) pathogenesis: cell origin, HHV-8 permissiveness, proliferation, genomic instability
- … RNA polymerase I-targeted ribozyme in prostate cancer gene therapy, and, The development and analysis of genomic instability-based transgenic models of …
- 774: COX2 Expression is Frequent in Advanced Urinary Bladder Cancer with Features of Genomic Instability
- Decoupling of Normal CD40/Interleukin-4 Immunoglobulin Heavy Chain Switch Signal Leads to Genomic Instability in RPMI 8226 and SGH-MM5 Multiple Myeloma …
- … growth factor (EGF) on invasive and metastatic potential of rat regressor tumor cell ER-1 Part 3: Oxidative stress and the induction of genomic instability by long-term …
- … mutagens, and are involved in genomic instability. It has been shown that damage of DNA and its precursors causes genomic instability. We have recently studied …
- Genomic stability and instability in different neuroepithelial tumors. A role for chromosome structure?
- 4-nitroquinoline-1-oxide induced Ha-ras point mutations are associated with loss of heterozygosity, gene amplification and genomic instability
- Genomic heterogeneity and instability of the AZF locus on the human Y chromosome
- … genomic hybridization and single-nucleotide polymorphism-loss of heterozygosity analysis reveals complex changes and multiple forms of chromosomal instability in …
- Frequent genomic alterations in epithelium measured by microsatellite instability following allogeneic hematopoietic cell transplantation in humans
- Large genomic duplicons map to sites of instability in the Prader-Willi/Angelman syndrome chromosome region (15q11–q13)
- … translocations are accompanied by chromosomal instability:: analysis of seven human colon cancer cell lines by comparative genomic hybridization and spectral …
- Short Telomeres Are Associated with Genetic Instability and the Occurrence of High Risk Genomic Aberrations in Chronic Lymphocytic Leukemia.
- Comparative genomic hybridization and chromosomal instability in solid tumours
- Chromosomal Instability and Genomic Amplification in Bone and Soft Tissue Tumours
- Pathophysiology of plaque instability: insights at the genomic level
- Unfavorable prognostic factors associated with high frequency of microsatellite instability and comparative genomic hybridization analysis in endometrial cancer
- Comment on” Chromosomal instability and tumors promoted by DNA hypomethylation” and” Induction of tumors in mice by genomic hypomethylation”
- Lerner’s theory on the genetic relationship between heterozygosity, genomic co-adaptation, and developmental instability revisited
- Genetic instability of adult T-cell leukemia/lymphoma by comparative genomic hybridization analysis
- Transgenic mice carrying large human genomic sequences with expanded CTG repeat mimic closely the DM CTG repeat intergenerational and somatic instability
- Genomic context drives SCA7 CAG repeat instability, while expressed SCA7 cDNAs are intergenerationally and somatically stable in transgenic mice
- Principal components analysis exposes a genomic basis for microsatellite instability status
- Increased Genome Instability in Escherichia coli lon Mutants: Relation to Emergence of Multiple-Antibiotic-Resistant (Mar) Mutants Caused by Insertion Sequence …
- Comparative Genomic Hybridization Detects Secondary Chromosomal Deletions in Escherichia coli K-12 MG1655 Mutants and Highlights Instability in the flhDC …
- Developmental instability of the Drosophila wing as an index of genomic perturbation and altered cell proliferation
- Carcinogenesis, genetic instability and genomic entropy: Insight derived from malignant brain tumor age specific mortality rate dynamics
- beta-Catenine as a genomic target of high-grade microsatellite instability in colorectal cancer
- Model-based clustering of genomic aberrations: Generalizing the instability selection network model
- Primary carcinoma of the fallopian tube: comparative genomic hybridization reveals high genetic instability and a specific, recurring pattern of chromosomal …
- Replication in mammalian cells recapitulates the locus-specific differences in somatic instability of genomic GAA triplet-repeats
- Karyotype, chromosome instability and other genomic alterations in epithelial cancers. Do they correlate?
- Stimulation of genetic instability and associated large genomic rearrangements in Streptomyces ambofaciens by three fluoroquinolones
- Extremely large chromosomal deletions are intimately involved in genetic instability and genomic rearrangements inStreptomyces glaucescens
- Genomic locus-specific differences in GAA triplet-repeat instability
- Analysis of microsatellite instability and X-inactivation in ovarian borderline tumors lacking numerical abnormalities by comparative genomic hybridization
- … instability and associated genome plasticity in Streptomyces ambofaciens: pulsed-field gel electrophoresis evidence for large DNA alterations in a limited genomic …
- Microsatellite instability and large, genomic alterations of DNA mismatch repair genes in the etiology of HNPCC and sporadic tumors
- Genomic instability—an evolving hallmark of cancer
- Genomic instability in cancer
- Genomic instability and cancer: lessons learned from human papillomaviruses
- Genomic instability and cancer: an introduction
- Genomic instability and cancer
- The patterns and dynamics of genomic instability in metastatic pancreatic cancer
- Genomic instability in induced stem cells
- Loss of A-type lamins and genomic instability
- Genomic instability in breast cancer: pathogenesis and clinical implications
- Genomic instability and the selection of treatments for cancer
- Mitotic catastrophe: a mechanism for avoiding genomic instability
- Hypomethylation of retrotransposable elements correlates with genomic instability in non‐small cell lung cancer
- The consequences of structural genomic alterations in humans: genomic disorders, genomic instability and cancer
- Transcription-replication encounters, consequences and genomic instability
- Mechanisms of cadmium induced genomic instability
- Mechanism of genomic instability in cells infected with the high-risk human papillomaviruses
- Nucleotide deficiency promotes genomic instability in early stages of cancer development
- Aneuploidy drives genomic instability in yeast
- c-MYC-induced genomic instability
- Genomic instability in iPS: time for a break
- Links between mutant p53 and genomic instability
- Mechanisms of programmed DNA lesions and genomic instability in the immune system
- Genomic instability and colon carcinogenesis: from the perspective of genes
- Spatial and temporal diversity in genomic instability processes defines lung cancer evolution
- Human embryonic stem cells reveal recurrent genomic instability at 20q11. 21
- Targeted and nontargeted effects of ionizing radiation that impact genomic instability
- Strong association between cancer and genomic instability
- The RAG2 C terminus suppresses genomic instability and lymphomagenesis
- Histone deacetylase inhibitors and genomic instability
- Genomic instability in pluripotent stem cells: implications for clinical applications
- MicroRNAs, genomic instability and cancer
- DNA structure-induced genomic instability in vivo
- Genomic instability and carcinogenesis: an update
- Escherichia coli induces DNA damage in vivo and triggers genomic instability in mammalian cells
- c-Myc: linking transformation and genomic instability
- Genomic instability in human cancer: Molecular insights and opportunities for therapeutic attack and prevention through diet and nutrition
- Flavonoids and genomic instability induced by ionizing radiation
- Role of genomic instability in arsenic-induced carcinogenicity. A review
- The gene expression signature of genomic instability in breast cancer is an independent predictor of clinical outcome
- How do cytokines trigger genomic instability?
- Terahertz radiation increases genomic instability in human lymphocytes
- Topoisomerase I suppresses genomic instability by preventing interference between replication and transcription
- Do bacterial genotoxins contribute to chronic inflammation, genomic instability and tumor progression?
- SPOP mutation leads to genomic instability in prostate cancer
- Effects of acute versus chronic hypoxia on DNA damage responses and genomic instability
- Polyubiquitination of proliferating cell nuclear antigen by HLTF and SHPRH prevents genomic instability from stalled replication forks
- High variability of genomic instability and gene expression profiling in different HeLa clones
- A selective requirement for 53BP1 in the biological response to genomic instability induced by Brca1 deficiency
- Prognostic impact of genomic instability in colorectal cancer
- Assessment of genomic instability in normal and diabetic rats treated with metformin
- Radiation-induced genomic instability: are epigenetic mechanisms the missing link?
- Genome-wide analysis of HPV integration in human cancers reveals recurrent, focal genomic instability
- Inactivation of murine Usp1 results in genomic instability and a Fanconi anemia phenotype
- TAp73 knockout shows genomic instability with infertility and tumor suppressor functions
- Genomic instability and myelodysplasia with monosomy 7 consequent to EVI1 activation after gene therapy for chronic granulomatous disease
- Limited mitochondrial permeabilization causes DNA damage and genomic instability in the absence of cell death
- Potential for genomic instability associated with retrotranspositionally-incompetent L1 loci
- Loss of RB1 induces non-proliferative retinoma: increasing genomic instability correlates with progression to retinoblastoma
- RECQL4 in genomic instability and aging
- R-loop-mediated genomic instability is caused by impairment of replication fork progression
- Alternative pathways of non-homologous end joining (NHEJ) in genomic instability and cancer
- Ploidy and Large-Scale Genomic Instability Consistently Identify Basal-like Breast Carcinomas with BRCA1/2 Inactivation
- Loss of Rb proteins causes genomic instability in the absence of mitogenic signaling
- Epigenetics and cancer without genomic instability
- Noncanonical mismatch repair as a source of genomic instability in human cells
- Complementary functions of ATM and H2AX in development and suppression of genomic instability
- Ribosomal proteins as unrevealed caretakers for cellular stress and genomic instability
- Smad4 loss in mice causes spontaneous head and neck cancer with increased genomic instability and inflammation
- Stem-like cancer cells are inducible by increasing genomic instability in cancer cells
- High-risk prostate cancer: a disease of genomic instability
- Profiles of genomic instability in high-grade serous ovarian cancer predict treatment outcome
- Crossing the LINE toward genomic instability: LINE-1 retrotransposition in cancer
- Med12 gain-of-function mutation causes leiomyomas and genomic instability
- Loss of the epigenetic tumor suppressor SNF5 leads to cancer without genomic instability
- Potential mechanisms of endogenous retroviral-mediated genomic instability in human cancer
- A 12-gene genomic instability signature predicts clinical outcomes in multiple cancer types
- Mutations in SPRTN cause early onset hepatocellular carcinoma, genomic instability and progeroid features
- Nucleosome loss leads to global transcriptional up-regulation and genomic instability during yeast aging
- Radiation-induced genomic instability
- Mitochondrial complex II dysfunction can contribute significantly to genomic instability after exposure to ionizing radiation
- γH2AX as a marker of DNA double strand breaks and genomic instability in human population studies
- Genomic instability may originate from imatinib-refractory chronic myeloid leukemia stem cells
- Genomic instability in multiple myeloma: mechanisms and therapeutic implications
- Induction of senescence with doxorubicin leads to increased genomic instability of HCT116 cells
- Genome-wide hypomethylation in head and neck cancer is more pronounced in HPV-negative tumors and is associated with genomic instability
- Plasmodium infection promotes genomic instability and AID-dependent B cell lymphoma
- Papillomavirus DNA replication—from initiation to genomic instability
- PTEN C-terminal deletion causes genomic instability and tumor development
- Mitotic spindle destabilization and genomic instability in Shwachman-Diamond syndrome
- SIRT6 recruits SNF2H to DNA break sites, preventing genomic instability through chromatin remodeling
- Dysfunctional homologous recombination mediates genomic instability and progression in myeloma
- MicroRNAs in mutagenesis, genomic instability, and DNA repair
- Hydrophobic bile acids, genomic instability, Darwinian selection, and colon carcinogenesis
- Genomic instability in myeloid malignancies: increased reactive oxygen species (ROS), DNA double strand breaks (DSBs) and error-prone repair
- Variant base excision repair proteins: contributors to genomic instability
- β-Catenin induces T-cell transformation by promoting genomic instability
- Ionizing radiation-induced oxidative stress, epigenetic changes and genomic instability: the pivotal role of mitochondria
- Cognitive impairment, genomic instability and trace elements
- Basal-like Breast cancer DNA copy number losses identify genes involved in genomic instability, response to therapy, and patient survival
- BRCA1 deficiency exacerbates estrogen-induced DNA damage and genomic instability
- Human embryonic stem cells and genomic instability
- Exposure to anticancer drugs can result in transgenerational genomic instability in mice
- Genomic instability in the PARK2 locus is associated with Parkinson’s disease
- Kinase-dead ATM protein causes genomic instability and early embryonic lethality in mice
- Concise review: Genomic instability in human stem cells: current status and future challenges
- Mutation of a single allele of the cancer susceptibility gene BRCA1 leads to genomic instability in human breast epithelial cells
- Short loop length and high thermal stability determine genomic instability induced by G‐quadruplex‐forming minisatellites
- … associated fibroblasts drives tumor-stroma co-evolution: A new paradigm for understanding tumor metabolism, the field effect and genomic instability in cancer cells
- Spartan deficiency causes genomic instability and progeroid phenotypes
- Cancer models, genomic instability and somatic cellular Darwinian evolution
- Convergent transcription at intragenic super-enhancers targets AID-initiated genomic instability
- Combining ATR suppression with oncogenic Ras synergistically increases genomic instability, causing synthetic lethality or tumorigenesis in a dosage-dependent …
- Regulation of Myc by miR-34c: A mechanism to prevent genomic instability?
- A Pan‐European Study of the C9orf72 Repeat Associated with FTLD: Geographic Prevalence, Genomic Instability, and Intermediate Repeats
- Overexpression of RAD51 suppresses recombination defects: a possible mechanism to reverse genomic instability
- How cancer cells hijack DNA double-strand break repair pathways to gain genomic instability
- Raf kinase inhibitor protein: mechanism of loss of expression and association with genomic instability
- Hypoxia causes downregulation of mismatch repair system and genomic instability in stem cells
- The yeast Pif1 helicase prevents genomic instability caused by G-quadruplex-forming CEB1 sequences in vivo
- A Polymerase Theta-dependent repair pathway suppresses extensive genomic instability at endogenous G4 DNA sites
- Genomic instability in breast and ovarian cancers: translation into clinical predictive biomarkers
- WEE1 inhibition and genomic instability in cancer
- PARI overexpression promotes genomic instability and pancreatic tumorigenesis
- Epstein–Barr Virus DNase (BGLF5) induces genomic instability in human epithelial cells
- NADPH oxidase inhibition attenuates total body irradiation-induced haematopoietic genomic instability
- Cell cycle checkpoint defects contribute to genomic instability in PTEN deficient cells independent of DNA DSB repair
- Genomic instability, defective spermatogenesis, immunodeficiency, and cancer in a mouse model of the RIDDLE syndrome
- Genomic instability en route to and from cancer stem cells
- Genomic instability: Crossing pathways at the origin of structural and numerical chromosome changes
- Interference between DNA replication and transcription as a cause of genomic instability
- Antimicrobial-induced DNA damage and genomic instability in microbial pathogens
- Genomic instability of gold nanoparticle treated human lung fibroblast cells
- Evolution of genomic instability in diethylnitrosamine‐induced hepatocarcinogenesis in mice
- Upregulation of FOXM1 induces genomic instability in human epidermal keratinocytes
- Telomere length, telomeric proteins and genomic instability during the multistep carcinogenic process
- The Epstein–Barr virus nuclear antigen-1 promotes genomic instability via induction of reactive oxygen species
- Dysregulation of DNA polymerase κ recruitment to replication forks results in genomic instability
- Inflammation‐mediated genomic instability: roles of activation‐induced cytidine deaminase in carcinogenesis
- Haploinsufficiency for BRCA1 leads to cell-type-specific genomic instability and premature senescence
- Genomic instability induced by human papillomavirus oncogenes
- High genomic instability predicts survival in metastatic high-risk neuroblastoma
- Three Epstein–Barr virus latency proteins independently promote genomic instability by inducing DNA damage, inhibiting DNA repair and inactivating cell cycle …
- Rac2-MRC-cIII–generated ROS cause genomic instability in chronic myeloid leukemia stem cells and primitive progenitors
- Six1 overexpression in mammary cells induces genomic instability and is sufficient for malignant transformation
- Gastric cancers of Western European and African patients show different patterns of genomic instability
- Oral ingestion of silver nanoparticles induces genomic instability and DNA damage in multiple tissues
- Amplification of HER2 is a marker for global genomic instability
- Chromosome-breakage genomic instability and chromothripsis in breast cancer
- Bacterial composition of the human upper gastrointestinal tract microbiome is dynamic and associated with genomic instability in a Barrett’s esophagus cohort
- Genomic instability and cancer: lessons from analysis of Bloom’s syndrome
- Ultradeep sequencing of a human ultraconserved region reveals somatic and constitutional genomic instability
- DNA replication timing, genome stability and cancer: late and/or delayed DNA replication timing is associated with increased genomic instability
- Genomic instability of human embryonic stem cell lines using different passaging culture methods
- Molecular mechanisms of low dose ionizing radiation-induced hormesis, adaptive responses, radioresistance, bystander effects, and genomic instability
- Cells expressing FLT3/ITD mutations exhibit elevated repair errors generated through alternative NHEJ pathways: implications for genomic instability and therapy
- Genomic instability and DNA damage responses in progeria arising from defective maturation of prelamin A
- DHX9 helicase is involved in preventing genomic instability induced by alternatively structured DNA in human cells
- Limiting replication stress during somatic cell reprogramming reduces genomic instability in induced pluripotent stem cells
- Whole-exome sequencing of human pancreatic cancers and characterization of genomic instability caused by MLH1 haploinsufficiency and complete deficiency
- One-hit wonders of genomic instability
- Genomic instability and radiation risk in molecular pathways to colon cancer
- The evolution of genomic instability in the obligate endosymbionts of whiteflies
- Induction of genomic instability, oxidative processes, and mitochondrial activity by 50 Hz magnetic fields in human SH-SY5Y neuroblastoma cells
- Fingerprinting genomic instability in oral submucous fibrosis
- Genomic instability in chronic renal failure patients
- Epstein-Barr virus BALF3 mediates genomic instability and progressive malignancy in nasopharyngeal carcinoma
- Cyclin E2 induces genomic instability by mechanisms distinct from cyclin E1
- BCR/ABL stimulates WRN to promote survival and genomic instability
- Analysis of genomic instability in the offspring of fathers exposed to low doses of ionizing radiation
- Chronic exposure to the cytolethal distending toxins of G ram‐negative bacteria promotes genomic instability and altered DNA damage response
- Histone demethylase JARID1C inactivation triggers genomic instability in sporadic renal cancer
- Solitary fibrous tumors: loss of chimeric protein expression and genomic instability mark dedifferentiation
- A germline polymorphism of DNA polymerase beta induces genomic instability and cellular transformation
- Accumulation of abasic sites induces genomic instability in normal human gastric epithelial cells during Helicobacter pylori infection
- Genomic instability of osteosarcoma cell lines in culture: impact on the prediction of metastasis relevant genes
- Oncogenic YAP promotes radioresistance and genomic instability in medulloblastoma through IGF2-mediated Akt activation
- Grape seed polyphenols and curcumin reduce genomic instability events in a transgenic mouse model for Alzheimer’s disease
- Regional genomic instability predisposes to complex dystrophin gene rearrangements
- EBV and genomic instability—a new look at the role of the virus in the pathogenesis of Burkitt’s lymphoma
- Regulation of DNA polymerase POLD4 influences genomic instability in lung cancer
- A stochastic carcinogenesis model incorporating multiple types of genomic instability fitted to colon cancer data
- Copy number losses define subgroups of dedifferentiated liposarcoma with poor prognosis and genomic instability
- Histone methyltransferase EZH2 induces Akt-dependent genomic instability and BRCA1 inhibition in breast cancer
- Mammalian BTBD12 (SLX4) protects against genomic instability during mammalian spermatogenesis
- Genomic instability in cultured stem cells: associated risks and underlying mechanisms
- KIAA1018/FAN1 nuclease protects cells against genomic instability induced by interstrand cross-linking agents
- IMP2/p62 induces genomic instability and an aggressive hepatocellular carcinoma phenotype
- Transcription and replication: breaking the rules of the road causes genomic instability
- Replication independent DNA double-strand break retention may prevent genomic instability
- Genomic instability in chronic myeloid leukemia: targets for therapy?
- Telomere Loss Provokes Multiple Pathways to Apoptosis and Produces Genomic Instability in Drosophila melanogaster
- Genomic instability and p53 alterations in patients with malignant glioma
- Genomic instability caused by hepatitis B virus: into the hepatoma inferno
- Nuclear remodeling as a mechanism for genomic instability in cancer
- DNA end resection by CtIP and exonuclease 1 prevents genomic instability
- Preventing AID, a physiological mutator, from deleterious activation: regulation of the genomic instability that is associated with antibody diversity
- BCR-ABL1–positive microvesicles transform normal hematopoietic transplants through genomic instability: Implications for donor cell leukemia
- Characterization of a novel mechanism of genomic instability involving the SEI1/SET/NM23H1 pathway in esophageal cancers
- Heavy ions, radioprotectors and genomic instability: implications for human space exploration
- Lung adenocarcinoma of never smokers and smokers harbor differential regions of genetic alteration and exhibit different levels of genomic instability
- Cyclooxygenase-2 induces genomic instability, BCL2 expression, doxorubicin resistance, and altered cancer-initiating cell phenotype in MCF7 breast cancer cells
- SEPT9_i1 and genomic instability: mechanistic insights and relevance to tumorigenesis
- Telomere‐mediated genomic instability and the clinico‐pathological parameters in breast cancer
- Genomic instability induced by mutant succinate dehydrogenase subunit D (SDHD) is mediated by O2-• and H2O2
- Mdmx promotes genomic instability independent of p53 and Mdm2
- HPV16 E6 and E7 proteins induce a chronic oxidative stress response via NOX2 that causes genomic instability and increased susceptibility to DNA damage in head …
- Coupling of V (D) J recombination to the cell cycle suppresses genomic instability and lymphoid tumorigenesis
- Paternal exposure to ethylnitrosourea results in transgenerational genomic instability in mice
- iPSC lines that do not silence the expression of the ectopic reprogramming factors may display enhanced propensity to genomic instability
- Large scale genomic instability as an additive prognostic marker in early prostate cancer
- Cadmium induced cell apoptosis, DNA damage, decreased DNA repair capacity, and genomic instability during malignant transformation of human bronchial …
- Mutational inactivation of TGFBR2 in microsatellite unstable colon cancer arises from the cooperation of genomic instability and the clonal outgrowth of transforming …
- A cancer-associated DNA polymerase δ variant modeled in yeast causes a catastrophic increase in genomic instability
- Longevity mutation in SCH9 prevents recombination errors and premature genomic instability in a Werner/Bloom model system
- Germ-line variant of human NTH1 DNA glycosylase induces genomic instability and cellular transformation
- Recurrent genomic instability of chromosome 1q in neural derivatives of human embryonic stem cells
- Radiation-generated short DNA fragments may perturb non-homologous end-joining and induce genomic instability
- Genomic instability in blood cells is able to predict the oral cancer risk: an experimental study in rats
- Genomic Instability of the Sex-Determining Locus in Atlantic Salmon (Salmo salar)
- Human DNA damage response and repair deficiency syndromes: linking genomic instability and cell cycle checkpoint proficiency
- Significance of genomic instability in breast cancer in atomic bomb survivors: analysis of microarray-comparative genomic hybridization
- Transgenerational genomic instability in children of irradiated parents as a result of the Chernobyl Nuclear Accident
- A genomic instability score in discriminating nonequivalent outcomes of BRCA1/2 mutations and in predicting outcomes of ovarian cancer treated with …
- Contrast enhancement in 1p/19q-codeleted anaplastic oligodendrogliomas is associated with 9p loss, genomic instability, and angiogenic gene expression
- Ribosomal protein S27-like is a physiological regulator of p53 that suppresses genomic instability and tumorigenesis
- Primary Microcephaly, Impaired DNA Replication, and Genomic Instability Caused by Compound Heterozygous ATR Mutations
- Ectopic expression of cancer/testis antigen SSX2 induces DNA damage and promotes genomic instability
- Genomic instability induced by 50 Hz magnetic fields is a dynamically evolving process not blocked by antioxidant treatment
- The moyamoya disease susceptibility variant RNF213 R4810K (rs112735431) induces genomic instability by mitotic abnormality
- Genomic instability of micronucleated cells revealed by single‐cell comparative genomic hybridization
- Transposable Elements as Stress Adaptive Capacitors Induce Genomic Instability in Fungal Pathogen Magnaporthe oryzae
- Beta human papillomavirus E6 expression inhibits stabilization of p53 and increases tolerance of genomic instability
- Abatement by naringin of lomefloxacin-induced genomic instability in mice
- Global and MGMT promoter hypomethylation independently associated with genomic instability of lymphocytes in subjects exposed to high-dose polycyclic aromatic …
- Polyploidy‐associated genomic instability in Arabidopsis thaliana
- Genomic instability in patients with type 2 diabetes mellitus on hemodialysis
- The tammar wallaby major histocompatibility complex shows evidence of past genomic instability
- Mitochondria regulate DNA damage and genomic instability induced by high LET radiation
- Long duration exposure to cadmium leads to increased cell survival, decreased DNA repair capacity, and genomic instability in mouse testicular Leydig cells
- Hexavalent chromium exposure, genomic instability and lung cancer
- Implications of genomic instability in the diagnosis and treatment of breast cancer
- Activating WASP mutations associated with X-linked neutropenia result in enhanced actin polymerization, altered cytoskeletal responses, and genomic instability in …
- Genomic instability, mutations and expression analysis of the tumour suppressor genes p14ARF, p15INK4b, p16INK4a and p53 in actinic keratosis
- Colon cancer-associated DNA polymerase β variant induces genomic instability and cellular transformation
- Array CGH and gene-expression profiling reveals distinct genomic instability patterns associated with DNA repair and cell-cycle checkpoint pathways in Ewing’s …
- … as neoadjuvant therapy for triple-negative and BRCA1/2 mutation–associated breast cancer with assessment of a tumor-based measure of genomic instability …
- Loss of polycystin-1 causes centrosome amplification and genomic instability
- Impairment of the telomere/telomerase system and genomic instability are associated with keratinocyte immortalization induced by the skin human papillomavirus type …
- … defence genes in myelofibrosis and related neoplasms. Potential implications of downregulation of Nrf2 for genomic instability and disease progression
- Progressive Genomic Instability in the FVB/KrasLA2 Mouse Model of Lung Cancer
- A study of genomic instability in early preneoplastic colonic lesions
- UV-C–Irradiated Arabidopsis and Tobacco Emit Volatiles That Trigger Genomic Instability in Neighboring Plants
- DNA-RNA hybrids contribute to the replication dependent genomic instability induced by Omcg1 deficiency
- Organelle DNA rearrangement mapping reveals U-turn-like inversions as a major source of genomic instability in Arabidopsis and humans
- Somatic complex I disruptive mitochondrial DNA mutations are modifiers of tumorigenesis that correlate with low genomic instability in pituitary adenomas
- Oxidative stress preferentially induces a subtype of micronuclei and mediates the genomic instability caused by p53 dysfunction
- Breast cancer risk and possible mechanisms of radiation-induced genomic instability in the Swedish hemangioma cohort after reanalyzed dosimetry
- Non-targeted and Delayed Effects of Exposure to Ionizing Radiation: I. Radiation-Induced Genomic Instability and Bystander Effects In Vitro
- Role of DNA damage and epigenetic DNA methylation changes in radiation-induced genomic instability and bystander effects in germline in vivo
- Mps1 as a link between centrosomes and genomic instability
- Impact of Pseudomonas aeruginosa Genomic Instability on the Application of Typing Methods for Chronic Cystic Fibrosis Infections
- Sonic Hedgehog signaling impairs ionizing radiation–induced checkpoint activation and induces genomic instability
- Emerging evidence for the role of genomic instability in male factor infertility
- Reducing MCM levels in human primary T cells during the G0→ G1 transition causes genomic instability during the first cell cycle
- GLI2 induces genomic instability in human keratinocytes by inhibiting apoptosis
- T-cell-specific deletion of Mof blocks their differentiation and results in genomic instability in mice
- Genomic instability in chronic airway inflammatory diseases
- Mutual regulation between DNA-PKcs and Snail1 leads to increased genomic instability and aggressive tumor characteristics
- p53-Driven apoptosis limits centrosome amplification and genomic instability downstream of NPM1 phosphorylation
- Opposite roles for p38MAPK-driven responses and reactive oxygen species in the persistence and resolution of radiation-induced genomic instability
- Development of cancer-initiating cells and immortalized cells with genomic instability
- Genomic instability resulting from Blm deficiency compromises development, maintenance, and function of the B cell lineage
- Loss of caspase-2 augments lymphomagenesis and enhances genomic instability in Atm-deficient mice
- High-level HOOK3 expression is an independent predictor of poor prognosis associated with genomic instability in prostate Cancer
- Genomic instability in newborn with short telomeres
- Genomic instability causes HGF gene activation in colon cancer cells, promoting their resistance to necroptosis
- Genomic instability and vascular aging: A focus on nucleotide excision repair
- Genomic instability and oncogene amplifications in colorectal adenomas predict recurrence and synchronous carcinoma
- What mechanisms/processes underlie radiation-induced genomic instability?
- The propensity for tumorigenesis in human induced pluripotent stem cells is related with genomic instability
- Genomic instability in a healthy elderly population: a pilot study of possible cytogenetic markers related to ageing
- Genomic instability and telomere fusion of canine osteosarcoma cells
- Mutations in XRCC4 cause primary microcephaly, short stature and increased genomic instability
- Correlation of MLH1 and MGMTexpression and promoter methylation with genomic instability in patients with thyroid carcinoma
- Dendritic cell–mediated activation-induced cytidine deaminase (AID)–dependent induction of genomic instability in human myeloma
- Long‐lasting genomic instability following arsenite exposure in mammalian cells: The role of reactive oxygen species
- Determination of genomic instability and DNA methylation effects of Cr on maize (Zea mays L.) using RAPD and CRED-RA analysis
- HDAC1 overexpression independently predicts biochemical recurrence and is associated with rapid tumor cell proliferation and genomic instability in prostate cancer
- Downregulation of CRNN gene and genomic instability at 1q21.3 in oral squamous cell carcinoma
- Does interference between replication and transcription contribute to genomic instability in cancer cells?
- BCR-ABL1 kinase inhibits uracil DNA glycosylase UNG2 to enhance oxidative DNA damage and stimulate genomic instability
- MicroRNA-22 suppresses DNA repair and promotes genomic instability through targeting of MDC1
- Persistent genomic instability in peripheral blood lymphocytes from Hodgkin lymphoma survivors
- Genomic instability after targeted irradiation of human lymphocytes: evidence for inter-individual differences under bystander conditions
- Genomic instability induced by α-pinene in Chinese hamster cell line
- Lamin A Δexon9 mutation leads to telomere and chromatin defects but not genomic instability
- Influence of the antifolate drug Methotrexate on the development of murine neural tube defects and genomic instability
- Genomic Instability Is Associated with Natural Life Span Variation in Saccharomyces cerevisiae
- RECQL5 suppresses oncogenic JAK2-induced replication stress and genomic instability
- Genomic instability and cellular stress in organ biopsies and peripheral blood lymphocytes from patients with colorectal cancer and predisposing pathologies
- JAK2 and genomic instability in the myeloproliferative neoplasms: a case of the chicken or the egg?
- DNA damage in cells exhibiting radiation-induced genomic instability
- Genomic instability in giant cell tumor of bone. A study of 52 cases using DNA ploidy, relocalization FISH, and array‐CGH analysis
- Mcph1/Brit1 deficiency promotes genomic instability and tumor formation in a mouse model
- Role of microRNAs and DNA methyltransferases in transmitting induced genomic instability between cell generations
- Ataxia-telangiectasia mutated (ATM) deficiency decreases reprogramming efficiency and leads to genomic instability in iPS cells
- Cytokinesis-block micronucleus assay adapted for analyzing genomic instability of human mesenchymal stem cells
- Genomic and epigenetic instability in colorectal cancer pathogenesis
- Early telomere shortening and genomic instability in tubo-ovarian preneoplastic lesions
- 56Fe particle exposure results in a long-lasting increase in a cellular index of genomic instability and transiently suppresses adult hippocampal neurogenesis in vivo
- Warburg effect and translocation-induced genomic instability: two yeast models for cancer cells
- Targeting homologous recombination and telomerase in Barrett’s adenocarcinoma: impact on telomere maintenance, genomic instability and tumor growth
- Genomic instability, driver genes and cell selection: Projections from cancer to stem cells
- Metabolic and environmental conditions determine nuclear genomic instability in budding yeast lacking mitochondrial DNA
- Induction of genomic instability in cultured human colon epithelial cells following exposure to isocyanates
- FAVL elevation in human tumors disrupts Fanconi anemia pathway signaling and promotes genomic instability and tumor growth
- Association of genomic instability, and the methylation status of imprinted genes and mismatch-repair genes, with neural tube defects
- CD24−/low stem-like breast cancer marker defines the radiation-resistant cells involved in memorization and transmission of radiation-induced genomic instability
- Mechanotransduction, metastasis and genomic instability
- Dioxin induces genomic instability in mouse embryonic fibroblasts
- Aberrant methylation and associated transcriptional mobilization of Alu elements contributes to genomic instability in hypoxia
- Radiation and chemotherapy bystander effects induce early genomic instability events: telomere shortening and bridge formation coupled with mitochondrial …
- Centromere Replication Timing Determines Different Forms of Genomic Instability in Saccharomyces cerevisiae Checkpoint Mutants During Replication Stress
- RAS promotes tumorigenesis through genomic instability induced by imbalanced expression of Aurora‐A and BRCA2 in midbody during cytokinesis
- Spatiotemporal regulation of DNA replication in the human genome and its association with genomic instability and disease
- Rsf-1, a chromatin remodeling protein, induces DNA damage and promotes genomic instability
- A novel function for HSF1-induced mitotic exit failure and genomic instability through direct interaction between HSF1 and Cdc20
- PCR-free method detects high frequency of genomic instability in prostate cancer
- Genomic instability and proliferative activity as risk factors for distant metastases in breast cancer
- A genetic variant of Aurora kinase A promotes genomic instability leading to highly malignant skin tumors
- The role of activation-induced deaminase in antibody diversification and genomic instability
- No Evidence for the in vivo Induction of Genomic Instability by Low Doses of 137Cs Gamma Rays in Bone Marrow Cells of BALB/cJ and C57BL/6J Mice
- Lack of Evidence for Genomic Instability in Autistic Children as Measured by the Cytokinesis‐Block Micronucleus Cytome Assay
- Chking and executing cell division to prevent genomic instability
- Inflammatory response to isocyanates and onset of genomic instability in cultured human lung fibroblasts
- Apc and p53 interaction in DNA damage and genomic instability in hepatocytes
- Intrastrand triplex DNA repeats in bacteria: a source of genomic instability
- Breast cancer risk among Swedish hemangioma patients and possible consequences of radiation-induced genomic instability
- Unlocking the steric gate of DNA polymerase η leads to increased genomic instability in Saccharomyces cerevisiae
- CDK4 deficiency promotes genomic instability and enhances Myc-driven lymphomagenesis
- Sociology in an age of genomic instability: Copy number variation, somatic mosaicism, and the fallen genome
- WR-1065, the active metabolite of amifostine, mitigates radiation-induced delayed genomic instability
- Correlation of levels and patterns of genomic instability with histological grading of invasive breast tumors
- Possible expressions of radiation-induced genomic instability, bystander effects or low-dose hypersensitivity in cancer epidemiology
- The problem of genomic instability of cultivated human stem cells
- Genomic instability after allogeneic hematopoietic cell transplantation is frequent in oral mucosa, particularly in patients with a history of chronic graft-versus-host …
- Rad51C is essential for embryonic development and haploinsufficiency causes increased DNA damage sensitivity and genomic instability
- Translational compensation of genomic instability in neuroblastoma
- Cytoplasmic accumulation of sequestosome 1 (p62) is a predictor of biochemical recurrence, rapid tumor cell proliferation, and genomic instability in prostate cancer
- Novel deletions causing pseudoxanthoma elasticum underscore the genomic instability of the ABCC6 region
- High-throughput SNP/CGH approaches for the analysis of genomic instability in colorectal cancer
- Topographical analysis of telomere length and correlation with genomic instability in whole mount prostatectomies
- Genomic instability and tumor‐specific DNA alterations in oral leukoplakias
- Molecular characterization of isocyanate-induced male germ-line genomic instability
- Epstein–Barr virus latent membrane protein 1 increases genomic instability through Egr-1-mediated up-regulation of activation-induced cytidine deaminase in B-cell …
- Rb1 Haploinsufficiency Promotes Telomere Attrition and Radiation-Induced Genomic Instability
- Foci formation of P53‐binding protein 1 in thyroid tumors: activation of genomic instability during thyroid carcinogenesis
- Genomic instability influences the transcriptome and proteome in endometrial cancer subtypes
- An improved method for genome wide DNA methylation profiling correlated to transcription and genomic instability in two breast cancer cell lines
- Learning networks from high dimensional binary data: An application to genomic instability data
- Pharmacotherapeutic implications of the association between genomic instability at chromosome 15q13. 3 and autism spectrum disorders
- Growth factor dependent regulation of centrosome function and genomic instability by HuR
- Genomic instability in the epidermis induced by atomic bomb (A‐bomb) radiation: A long‐lasting health effect in A‐bomb survivors
- Molecular subtypes in stage II-III colon cancer defined by genomic instability: early recurrence-risk associated with a high copy-number variation and loss of …
- WEE1 murine deficiency induces hyper-activation of APC/C and results in genomic instability and carcinogenesis
- Myc oncogene-induced genomic instability: DNA palindromes in bursal lymphomagenesis
- Genomic instability: a stronger prognostic marker than proliferation for early stage luminal breast carcinomas
- Thyrotropin Signaling Confers More Aggressive Features with Higher Genomic Instability on BRAFV600E-Induced Thyroid Tumors in a Mouse Model
- p38 MAPK stress signalling in replicative senescence in fibroblasts from progeroid and genomic instability syndromes
- Loss of CHFR in human mammary epithelial cells causes genomic instability by disrupting the mitotic spindle assembly checkpoint
- Genomic instability: The driving force behind refractory/relapsing Hodgkin’s lymphoma
- Genomic instability in human lymphocytes from male users of crack cocaine
- Sarcoid-derived fibroblasts: links between genomic instability, energy metabolism and senescence
- Estrogens and genomic instability in human breast cancer cells—involvement of Src/Raf/Erk signaling in micronucleus formation by estrogenic chemicals
- Hydrogen peroxide induced genomic instability in nucleotide excision repair-deficient lymphoblastoid cells
- Role of pro-inflammatory cytokines in radiation-induced genomic instability in human bronchial epithelial cells
- Lack of genomic instability in bone marrow cells of SCID mice exposed whole-body to low-dose radiation
- Genomic instability and mouse microRNAs
- Radio-protective effect of cinnamic acid, a phenolic phytochemical, on genomic instability induced by X-rays in human blood lymphocytes in vitro
- Genomic instability in patients with autosomal-dominant polycystic kidney disease
- Genomic instability at both the base pair level and the chromosomal level is detectable in earliest PanIN lesions in tissues of chronic pancreatitis
- Effects of hTERT on genomic instability caused by either metal or radiation or combined exposure
- Genomic instability demonstrates similarity between DCIS and invasive carcinomas
- Acquired genomic aberrations associated with methotrexate resistance vary with background genomic instability
- A polyglutamine expansion disease protein sequesters PTIP to attenuate DNA repair and increase genomic instability
- Malignant fibrous histiocytoma two years after autologous stem cell transplant for Hodgkin lymphoma: evidence for genomic instability
- Genomic instability in sunflower interspecific hybrids
- BLM protein mitigates formaldehyde-induced genomic instability
- … , but not purines, determine recombination activating gene (RAG)-induced breaks on heteroduplex DNA structures: implications for genomic instability
- Genomic Instability in Mice Is Greater in Fanconi Anemia Caused by Deficiency of Fancd2 than Fancg
- A germline polymorphism of thymine DNA glycosylase induces genomic instability and cellular transformation
- Identification of a predominant co-regulation among kinetochore genes, prospective regulatory elements, and association with genomic instability
- Tracking genomic instability within irradiated and bystander populations
- Alteration of p53‐binding protein 1 expression during skin carcinogenesis: association with genomic instability
- Estimating genomic instability mediated by Alu retroelements in breast cancer
- … bile acid-induced micronuclei formation, mitotic perturbations, and decreases in spindle checkpoint proteins: relevance to genomic instability in colon carcinogenesis
- Intrachromosomal changes and genomic instability in site-specific microbeam-irradiated and bystander human-hamster hybrid cells
- Learning oncogenic pathways from binary genomic instability data
- Assessment of mutational load in biopsy tissue provides additional information about genomic instability to histological classifications of Barrett’s esophagus
- Synergistic interaction of Rnf8 and p53 in the protection against genomic instability and tumorigenesis
- DNA hypomethylation and oxidative stress-mediated increase in genomic instability in equine sarcoid-derived fibroblasts
- An array CGH based genomic instability index (G2I) is predictive of clinical outcome in breast cancer and reveals a subset of tumors without lymph node …
- Mobilization of LINE-1 in irradiated mammary gland tissue may potentially contribute to low dose radiation-induced genomic instability
- R/G-band boundaries: genomic instability and human disease
- Genomic instability in the breast microenvironment? A critical evaluation of the evidence
- The effect of growth architecture on the induction and decay of bleomycin and X-ray-induced bystander response and genomic instability in lung adenocarcinoma …
- MRE11 and H2AX biomarkers in the response to low-dose exposure: balance between individual susceptibility to radiosensitivity and to genomic instability
- Studying age-dependent genomic instability using the S. cerevisiae chronological lifespan model
- Genomic instability of surgical sample and cancer-initiating cell lines from human glioblastoma
- ATM deficiency augments constitutively nuclear cyclin D1-driven genomic instability and lymphomagenesis
- Effects of As2O3 on DNA methylation, genomic instability, and LTR retrotransposon polymorphism in Zea mays
- CCAAT/enhancer-binding protein δ mediates tumor necrosis factor α-induced Aurora kinase C transcription and promotes genomic instability
- Loss of LIN9, a member of the DREAM complex, cooperates with SV40 large T antigen to induce genomic instability and anchorage-independent growth
- Folate deficiency is not associated with increased mitochondrial genomic instability: results from dietary intake and lymphocytic mtDNA 4977-bp deletion in healthy …
- Protein profiling of genomic instability in endometrial cancer
- The neuro-glial-vascular interrelations in genomic instability symptoms
- Inactivation of chk2 and mus81 leads to impaired lymphocytes development, reduced genomic instability, and suppression of cancer
- Quantitative proteomic analysis of mitochondrial proteins reveals prosurvival mechanisms in the perpetuation of radiation-induced genomic instability
- Biomarkers of genotoxicity and genomic instability in a non-human primate, Cebus libidinosus (Cebidae, Platyrrhini), exposed to nitroimidazole derivatives
- A quantitative analysis of genomic instability in lymphoid and plasma cell neoplasms based on the PIG-A gene
- Increased frequency of micronuclei in lymphocytes of infertile males after exposure to gamma irradiation: a possible sign of genomic instability
- Variability in estrogen-metabolizing genes and their association with genomic instability in untreated breast cancer patients and healthy women
- Double‐strand break repair‐adox: restoration of suppressed double‐strand break repair during mitosis induces genomic instability
- Genomic instability and copy-number heterogeneity of chromosome 19q, including the kallikrein locus, in ovarian carcinomas
- Appearance of epithelial and stromal genomic instability in background colorectal mucosa of sporadic colorectal cancer patients: relation to age and gender
- Loss of the Thioredoxin Reductase Trr1 Suppresses the Genomic Instability of Peroxiredoxin tsa1 Mutants
- Evolutionary comparison of the mechanism of DNA cleavage with respect to immune diversity and genomic instability
- Genomic instability in patients with non-small cell lung cancer assessed by the arbitrarily primed polymerase chain reaction
- Gene signatures of genomic instability as prognostic tools for breast cancer
- Colorectal carcinomas from Middle East. Molecular and tissue microarray analysis of genomic instability pathways.
- Genomic instability in the brain: etiology, pathogenesis and new biological markers of psychiatric disorders
- ICAD deficiency in human colon cancer and predisposition to colon tumorigenesis: linkage to apoptosis resistance and genomic instability
- Genomic Instability of I Elements of Drosophila melanogaster in Absence of Dysgenic Crosses
- Significance of p53‐binding protein 1 nuclear foci in uterine cervical lesions: endogenous DNA double strand breaks and genomic instability during carcinogenesis
- Prognostic significance of cell cycle-and invasion-related molecular markers and genomic instability in primary carcinoma of the vagina
- Loss of the Histone Pre-mRNA Processing Factor Stem-Loop Binding Protein in Drosophila Causes Genomic Instability and Impaired Cellular Proliferation
- Regeneration in sugarcane via somatic embryogenesis and genomic instability in regenerated plants
- Functional significance of Aurora kinase A in centrosome amplification and genomic instability
- Deregulated expression of DNA polymerase β is involved in the progression of genomic instability
- Telomere alterations and genomic instability in long-term cultures of normal human fibroblasts irradiated with X rays and protons
- Nitric oxide coordinates development of genomic instability in realization of combined effect with ionizing radiation
- Loss of anchorage in checkpoint-deficient cells increases genomic instability and promotes oncogenic transformation
- Telomere-centromere-driven genomic instability contributes to karyotype evolution in a mouse model of melanoma
- Large‐scale genomic instability in colon adenocarcinomas and correlation with patient outcome
- LINE-1 activity as molecular basis for genomic instability associated with light exposure at night
- Breast cancer risk after radiation treatment at infancy: potential consequences of radiation-induced genomic instability
- RAPD-based detection of genomic instability in cucumber plants derived from somatic embryogenesis
- Repetitive sequences, genomic instability, and Barrett’s esophageal adenocarcinoma
- Genomic instability in human actinic keratosis and squamous cell carcinoma
- Telomere attrition and genomic instability in xeroderma pigmentosum type‐b deficient fibroblasts under oxidative stress
- Niacin status and genomic instability in bone marrow cells; mechanisms favoring the progression of leukemogenesis
- An update on the mechanisms and pathophysiological consequences of genomic instability with a focus on ionizing radiation
- Genomic instability and histone H3 phosphorylation induction by the Ras‐mitogen activated protein kinase pathway in pancreatic cancer cells
- Genomic instability in context of the chromosomal theory
- Developmental defects and genomic instability after x-irradiation of wild-type and genetically modified mouse pre-implantation and early post-implantation embryos
- Linking PTEN with genomic instability and DNA repair
- Genomic Instability in Regions Adjacent to a Highly Conserved pch Prophage in Escherichia coli O157:H7 Generates Diversity in Expression Patterns of the LEE …
- Widespread Genomic Instability Mediated by a Pathway Involving Glycoprotein Ibα and Aurora B Kinase
- Increased genomic instability and altered chromosomal protein phosphorylation timing in HRAS‐transformed mouse fibroblasts
- Reducing genomic instability in iPSCs
- Genomic instability induced by ionizing radiation in human hepatocytes
- Mitochondrial Genomic Instability in Colorectal Cancer: No Correlation to Nuclear Microsatellite Instability and Allelic Deletion of hMSH2, hMLH1, and p53 Genes …
- Chlorpyrifos Induces MLL Translocations Through Caspase 3-Dependent Genomic Instability and Topoisomerase II Inhibition in Human Fetal Liver Hematopoietic …
- Chk2 protects against radiation-induced genomic instability
- RAD51 can inhibit PDGF-B–induced gliomagenesis and genomic instability
- Progressive genomic instability in the Nup98-HoxD13 model of MDS correlates with loss of the PIG-A gene product
- Genomic Instability and Cancer Metastasis: Mechanisms, Emerging Themes, and Novel Therapeutic Strategies
- Effect of Cu supplementation on genomic instability in chemically-induced mammary carcinogenesis in the rat
- Transformation, genomic instability and senescence mediated by platelet/megakaryocyte glycoprotein Ibα
- Continuous in vitro exposure to low-dose genistein induces genomic instability in breast epithelial cells
- Ionizing radiation-induced genomic instability in CHO cells is followed by selection of radioresistant cell clones
- Hyperdiploidy tetraploidization and genomic instability in breast cancer–a case report study
- Genomic instability in complicated and uncomplicated Egyptian schistosomiasis haematobium patients
- Induction of genomic instability after an acute whole-body exposure of mice to 56Fe ions
- The role of the chlamydial effector CPAF in the induction of genomic instability
- Long-term persistence of X-ray-induced genomic instability in quiescent normal human diploid cells
- Transposable elements occur more frequently in autism-risk genes: Implications for the role of genomic instability in autism
- Comparison of Proliferation and Genomic Instability Responses to WRN Silencing in Hematopoietic HL60 and TK6 Cells
- Geosmin induces genomic instability in the mammalian cell microplate-based comet assay
- Enhanced micronucleus formation in the descendants of γ-ray-irradiated tobacco cells: Evidence for radiation-induced genomic instability in plant cells
- Secondary radiation-induced bone tumours demonstrate a high degree of genomic instability predictive of a poor prognosis
- Subtle genomic alterations and genomic instability revealed in diploid cancer cell lines
- Transgenerational transmission of radiation-induced genomic instability and predisposition to carcinogenesis
- Dysfunctional telomeres promote genomic instability and metastasis in the absence of telomerase activity in oncogene induced mammary cancer
- Genomic instability and DNA ploidy are linked to DNA copy number aberrations of 8p23 and 22q11. 23 in gastric cancers
- Individual susceptibility to radiosensitivity and to genomic instability: its impact on low-dose phenomena
- Nitric Oxide: Genomic Instability And Synthetic Lethality
- Genomic instability in patients with Barrett’s esophagus
- … time-dependent changes of micronucleus frequency and gene expression in the progeny of irradiated cells: Two components in radiation-induced genomic instability …
- Role of Ku80-dependent end-joining in delayed genomic instability in mammalian cells surviving ionizing radiation
- Hormone escape is associated with genomic instability in a human prostate cancer model
- Epigenetic gene silencing is a novel mechanism involved in delayed manifestation of radiation-induced genomic instability in mammalian cells
- Genomic instability in liver cells caused by an LPS-induced bystander-like effect
- Genomic instability at the 13q31 locus and somatic mtDNA mutation in the D-loop site correlate with tumor aggressiveness in sporadic Brazilian breast cancer …
- Transgenerational developmental effects and genomic instability after x-irradiation of preimplantation embryos: Studies on two mouse strains
- Cancer models, ionizing radiation, and genomic instability: a review
- Hepatocyte nuclear factor 1β induced by chemical stress accelerates cell proliferation and increases genomic instability in mouse liver
- Genetic alterations, genomic instability and cancer in celiac disease
- ATM in prevention of genomic instability
- Tracking profiles of genomic instability in spontaneous transformation and tumorigenesis
- Genomic instability in chidren born after the Chernobyl nuclear accident (in vivo and in vitro studies)
- Aberrant Non-Homologous End Joining in Multiple Myeloma: A Role in Genomic Instability and As Potential Prognostic Marker.
- The low-dose phenomenon: How bystander effects, genomic instability, and adaptive responses could transform cancer-risk models
- Genomic instability in blood cells from murine model of mucopolysaccharidosis type I
- Akt promotes tumorigenesis in part through modulating genomic instability via phosphorylating XLF
- Renal genomic instability induced by aspartame and the possible influence of the flaxseed oil and coenzyme Q10 in male rats
- No evidence for transgenerational genomic instability in the F1 or F2 descendants of Muta™ Mouse males exposed to N-ethyl-N-nitrosourea
- … -Induced Complex Chromosome Exchanges Transmitted through Extra-Thymic Lymphopoiesis In Vitro Show Evidence of Emerging Genomic Instability
- The R280H X-ray cross-complementing 1 germline variant induces genomic instability and cellular transformation
- Effect of silver nanoparticle and glycyrrhizic acid (SN-GLY) complex on repair of whole body radiation-induced cellular DNA damage and genomic instability in mice
- Genomic Instability or One-Gene Theory for Tumor Progression: A Breast Cancer Study
- R-loops and genomic instability in Bre1 (RNF20/40)-deficient cells
- Increased genomic instability in somatic cells of the progeny of female mice exposed to acute X-radiation in the preconceptional period
- Genomic instability and repair mediated by common repeated sequences
- Analysis of genomic instability in adult-onset celiac disease patients by microsatellite instability and loss of heterozygosis
- CMTX1 patients’ cells present genomic instability corrected by CamKII inhibitors
- Genomic instability in chidren born after the Chernobyl Nuclear Accident (in vivo and in vitro studies)
- No influence of serotonin levels in foetal bovine sera on radiation-induced bystander effects and genomic instability
- CpG site-specific RASSF1a hypermethylation is associated with occupational PAH exposure and genomic instability
- Malaria-induced B cell genomic instability
- The Transient Inactivation of the Master Cell Cycle Phosphatase Cdc14 Causes Genomic Instability in Diploid Cells of Saccharomyces cerevisiae
- Multifunctionality of MDM2 protein and its role in genomic instability of cancer cells
- Cellular exposure to muscle relaxants and propofol could lead to genomic instability in vitro
- Role of alteration/deficiency in activation (ADA) complex in cell cycle, genomic instability and cancer
- Genomic instability in quartz dust exposed rat lungs: Is inflammation responsible?
- PI3Kdelta inhibitors increase genomic instability by upregulating aid expression
- Genomic instability measured by inter-(simple sequence repeat) PCR and high-resolution microsatellite instability are prognostic of colorectal carcinoma survival after …
- Hyperproliferation in nasal polyposis tissues is not associated with somatic genomic instability.
- A role for reactive oxygen species in the resolution of persistent genomic instability after exposure to radiation
- Rac2-mitochondrial respiratory chain complex III-generated ROS cause genomic instability in chronic myeloid leukemia stem cells and primitive progenitors
- Radiation-induced genomic instability and radiation sensitivity
- Epigenetic inactivation of the RB1 gene as a factor of genomic instability: A possible contribution to etiology of chromosomal mosaicism during human embryo …
- INMAP Overexpression Inhibits Cell Proliferation, Induces Genomic Instability and Functions through p53/p21 Pathways
- Early telomere shortening and genomic instability in tubo-ovarian preneoplastic lesions—response
- The generation, detection, and prevention of genomic instability during cancer progression and metastasis
- Glutathione S-transferase gene polymorphisms in celiac disease and their correlation with genomic instability phenotype
- Restoration of proliferation ability with increased genomic instability from Rad2p-induced mitotic catastrophe in Saccharomyces cerevisiae
- A novel diagnostic method targeting genomic instability in intracystic tumors of the breast
- Genomic instability in the offspring of irradiated parents
- Mechanisms generating free radicals in CML stem/progenitor cell populations causing DNA damage and genomic instability
- Detection of genomic instability in hypospadias patients by random amplified polymorphic DNApolymerase chain reaction (RAPD-PCR) method
- Effect of genomic instability and mutations on the signaling pathways in colon cancer cells
- Increased genomic instability may contribute to the development of kinase domain mutations in chronic myeloid leukemia
- Nuclear and mitochondrial genome defects in Autism: Genomic instability and impact of epigenetic and environmental factors
- Nuclear DNA-content in mesenchymal lesions in dogs: its value as marker of malignancy and extent of genomic instability
- Genomic instability and immortality in cancer
- Confounding by repetitive elements and CpG islands does not explain the association between hypomethylation and genomic instability
- Genomic instability in ulcerative colitis: a prerequisite for cancer in the inflammatory colon?
- RNF8-independent Lys63 poly-ubiquitylation prevents genomic instability in response to replication-associated DNA damage
- NUAK1 links genomic instability and senescence
- Genomic instability in obesity-associated colon cancer
- Genomic instability originates from leukemia stem cells in a mouse model of CML-CP
- … into account the emotional tension of adults and children in the evaluation of the influence of environmental factors on genomic instability and sensitivity: results and …
- Molecular studies on Aβ (42) induced genomic instability in aged rabbit brain
- Genomic instability in fanconi anemia results from a combination of chromosome mis-segregation in mitosis and unresolved interphase DNA damage
- … (PTP) inhibition enhances chromosomal stability after genotoxic stress: Decreased chromosomal instability (CIN) at the expense of enhanced genomic instability (GIN …
- Detection of genomic instability in oral squamous cell carcinoma using random amplified polymorphic DNA based on polymerase chain reaction method (RAPD …
- … Macroglobulinemia Shows Highly Variable Subclonal Distribution, and Multiple Mutations within Individual Patients Indicative of Targeted Genomic Instability
- Abstract NG01: SPOP mutation is associated with genomic instability in prostate cancer
- Analysis of genomic instability in patients with breast cancer
- MYC overexpression combined with Pten loss generates genomic instability and rapid metastasis in a new mouse model of lethal prostate adenocarcinoma.
- Comprehensive characterization of genomic instability in pluripotent stem cells and their derived neuroprogenitor cell lines
- Nuclease activity is associated with genomic instability as well as survival in myeloma; underlying mechanisms and significance
- The Role of Stem Cell Genomic Instability in Aging
- Involvement of Non-Homologous End-Joining in Radiation-Induced Genomic Instability
- Genomic instability in oral cancer: An update and review
- The effect of treatment of chrysotile with chloride iron (III) on the effect of genomic instability in cultured human lymphocytes
- Spontaneous DNA Damage and Aberrant Epigenome In Multiple Myeloma Constitute The Path To Disease Genomic Instability
- Mitotic spindle dysfunction promotes genomic instability in marrow failure
- MicroRNA-19b enhances heavy ion induced genomic instability by down-regulation of BTG1
- New facts in favor of the absence of genomic instability induced by low doses of low LET radiation and conclusions about the threshold effect reported in the …
- Genomic instability in pre-neoplastic colonic lesions
- Problems with genomic instability in cells of young children associate with problems of their family and teacher
- Genomic instability and rapid clinical course in adult T-cell lymphoma/leukemia patient
- Targeting aberrant non-homologous end joining in multiple myeloma: Role of the classical and alternative pathways in genomic instability
- Comments on Rithidech, KN; et al. Lack of Genomic Instability in Bone Marrow Cells of SCID Mice Exposed Whole-Body to Low-Dose Radiation. Int. J. Environ. Res …
- … 04-03: Deconvoluting immune cell populations using ‘in silico flow cytometry’with CIBERSORT: Association with neoadjuvant therapy response and genomic instability …
- Genomic instability establishes dependencies on acquired gene regulatory networks: A novel role of p62 in myeloid malignancies with del (5q)
- Unraveling genomic instability in multiple myeloma-Mechanisms, biological and clinical implications
- Transgene Expression Facilitated by the v-src Splice Acceptor Can Impair Replication Kinetics and Lead to Genomic Instability of Rous Sarcoma Virus-Based Vectors
- Genomic Instability in Colorectal Cancer; from Bench to Bed.
- Cell genomic instability in pathological conditions of infectious genesis
- Investigating the role of cyelin D1 in the promotion of genomic Instability and breast cancer
- CEP55 is a determinant of genomic instability in aneuploid breast cancer cells and facilitates anti-mitotic drugs resistance by interacting directly with HSF1
- Analysis of genomic instability in primary spermatocytes of interspecific hybrids of the red fox (Vulpes vulpes) and the Arctic fox (Alopex lagopus)
- Targeting Rac2-Mitochondrial Respiratory Chain Complex III Signaling to Prevent Genomic Instability in Leukemia Stem and Progenitor Cells
- Genomic instability: Ada3 and HPV E6-acetyltransferase connections?
- OC-123 Obesity drives radioresistance and enhances genomic instability in oesophageal adenocarcinoma
- XRCC1 deficiency influences the cytotoxicity and the genomic instability induced by Me-lex, a specific inducer of N3-methyladenine
- BCR-ABL1 kinase inhibits DNA glycosylases to enhance oxidative DNA damage and stimulate genomic instability
- The role of telomere dysfunction in driving genomic instability
- Gene Mutation as Biomarker of Radiation Induced Cell Injury and Genomic Instability
- Abstract PR-10: PARP inhibition induces genomic instability in normal human cells.
- Intraclonal recovery of ‘slow clones’—a manifestation of genomic instability: Are mitochondria the key to an explanation?
- DNA and chromosomal damage as a hallmark of the induced genomic instability in barley
- Epigenetic changes suggest genomic instability in IPF patient samples compared to controls
- Transgenerational genomic instability in children of liquidators of the accident at the ChNPP (cytogenetic and immunogenetic characteristics)
- 142 SOMATIC AND GENOMIC INSTABILITY OF ANDROGEN RECEPTOR IN AFRICAN AMERICANS WITH PROSTATE CANCER
- Study of Genomic Instability of Arabidopsis Thaliana Induced by Low energy ion Radiation
- Genomic instability induced by low-dose ionizing radiation and tumor necrosis factor-alpha
- Analysis of Genomic Instability and Tumor-Specific Genetic Alterations by Arbitrarily Primed PCR
- Signs of late radiation-induced genomic instability in persons chronically exposed to radiation.
- The tumor suppressor APC/CCdh1 and its role in replication stress and the origin of genomic instability
- Assessment of genomic instability in blood and tissues from prostate cancer patients by random amplified polymorphic DNA analysis
- Dysregulation of SHFM1, a novel target for prevention of genomic instability in myeloma, is associated with epigenetic changes at specific CpG Sites
- Mathematical modelling of the radiation-induced bystander effect and transmissible genomic instability applied to cancer
- The magic trick of hepatocytes: uncoupling genomic instability from cancer
- A computational homology analysis of CGH data finds recurrent genomic instability in older breast cancer patients
- 41. Cyclooxygenase-2 Induces Genomic Instability, BCL2 Expression, Doxorubicin Resistance, and Altered Cancer Initiating Cell Phenotype in MCF7 Breast Cancer …
- Non Homologous end joining, a marker of genomic instability is elevated in multiple myeloma: a new prognostic factor
- Investigation of Genomic Instability in Patients with Sjögren’s Syndrome by Using Sister Chromatid Exchange Analysis.
- Induction of genomic instability after an acute whole-body exposure of mice to 56Fe ions
- Hematopoietic Cells Undergo Homotypic Cell Fusion: A Novel Platform to Study Genomic Instability and Leukemogenesis.
- Telomere-mediated genomic instability in cells from ataxia telangiectasia patients
- Of Mice and Men: the Nonrandom Genomic Instability in HepatocarcinogenesisΔσ
- Genomic instability associated to impairment of Fe-S clusters synthesis in Saccharomyces cerevisiae yeast cells
- 11q21. 1‐11q23. 3 Is a site of intrinsic genomic instability triggered by irradiation
- New insights in the development of biological chimeras: Genomic instability and epithelial chimerism after hematopoietic stem cell transplantation
- Genomic instability and activation of the DNA damage response pathway is an independent predictor of poor prognosis, is associated with MYC expression …
- Colorectal cancers in patients with the (9A/6A) polymorphism of TGFBR1 exhibit lesser inter-(simple sequence repeat) PCR genomic instability and present clinically …
- Initiation of Genomic Instability, Cellular Senescence, and Organismal Aging by Dysfunctional Telomeres
- ATR checkpoint kinase suppression in combination with oncogenic Ras expression synergistically increases genomic instability and potentiates tumorigenesis in mice
- Methylation status of endogenous DNA double strand breaks: possible connection between genomic hypomethylation and instability
- Oxidative stress induces DNA strand breaks may lead to genomic instability in ovarian tumorigenesis
- Bridging genomic instability disorders
- Immunomodulation and Genomic Instability
- Retraction: Cadmium induced cell apoptosis, DNA damage, decreased DNA repair capacity, and genomic instability during malignant transformation of human …
- ROS-Induced DNA Damage Causing Genomic Instability in CML Stem and/or Progenitor Cells and in Quiescent and/or Proliferating Cells: Role of Mitochondrial …
- Genomic instability in atherosclerosis
- Physiological responses to genomic instability
- Analysis of Genomic Instability in Colorectal Carcinoma
- Genomic instability and carcinogenesis
- Genomic Instability and Breast Cancer
- Abstract LB-103: Circulating chromatin is a novel DNA damaging agent that induces genomic instability and malignant transformation
- 3D nuclear organization and genomic instability in cancer
- Carcinogenesis and Genomic Instability I
- Genomic Instability and the Mechanical Microenvironment
- Genomic Instability, Inflammation, and Cancer
- Final Technical Report-Mechanisms and pathways controlling genomic instability
- Impact of genomic instability in colorectal cancers
- Nucleotide shortage and genomic instability
- Role of genomic instability within the context of chromosomal rerrangements
- Radiation-induced retroelement-mediated genomic instability
- Genomic instability in South African breast cancer patients
- Mechanisms and role of genomic instability in radiation-induced carcinogenesis
- Causation of cancer by ionizing radiation and genomic instability
- Mechanisms of c-Myc dependent genomic instability
- Genomic Instability, Inflammation, and Cancer
- Mechanisms of Low Dose Radio-Suppression of Genomic Instability
- Genomic Instability in Acute Transformation of Chronic Myelogenous Leukemia
- Characterization of genomic instability in Saccharomyces cerevisiae and engaging teaching strategies described in two curricula
- Role of genomic instability in gastric carcinogenesis
- The patterns and dynamics of genomic instability in metastatic pancreatic cancer
- The role of genomic instability for estimating the formation of radiodeterminated pathology in children living in radiocontaminated regions; Rol’genomnoj nestabil’nosti …
- Timing and importance of genomic instability in colorectal tumourigenesis, and association with clinico-pathological features
- Genomic instability in mice long term after radiation exposure at low dozes
- Laboratory of Genomic Instability Control and Mitochondria Dynamics
- Stem Cell Survival in the Face of Genomic Instability
- Genomic Instability-Indicated Mechanisms of Early Carcinogenesis Following Hepatocarcinogen Treatment
- Cancer genesis models with radiation-induced genomic instability: application to two epide, miological cohortes; Krebsentstehungsmodelle mit strahleninduzierter …
- Genomic instability of breast stroma
- Genomic Instability Resulting from Blm
- Microenvironment-Induced Genomic Instability in Multiple Myeloma
- Bcr. Abl induced genomic instability & progression of disease in CML
- GENOMIC INSTABILITY IN POST-MORTEM AUTISTIC BRAINS AND CORRELATION WITH GENE EXPRESSION LEVELS
- Exposure to microgravity environment may induce genomic instability
- Connections between Genomic Instability and Cancer Stem Cells
- THE ROLE OF OXIDATIVE STRESS AND MITOCHONDRIAL DEFECTS IN GENOMIC INSTABILITY
- Analysis of Heterochromatin-Associated Genomic Instability
- Radiation-induced genomic instability and LINE-1 hypomethylation in radiographers
- CML-CP Mouse Model of Genomic Instability.
- Evaluation of genomic instability as an early event in the progression of breast cancer
- HBx targets centrosomal protein TAX1BP2 to promote genomic instability
- Evaluation of Genomic Instability in the Abnormal Prostate PRINCIPAL INVESTIGATOR
- Genomic instability of human pluripotent cells
- Genomic Instability, DNA Repair Pathways and Cancer
- Genomic instability within the short arm of chromosome 1 in colorectal cancer
- Genomic instability in hepatitis B virus-induced hepatoma and its clinical implication
- The Role of Telomere Dysfunction in Driving Genomic Instability
- Causes and Consequences of Genomic Instability in Prostatic Carcinogenesis
- Genomic instability induced by heat-inactivated bacteria: Implication to tumorigenesis
- Genomic instability in non-targeted bystander mammalian cells
- TGF-β enforces genomic instability in liver cancers
- Transcription and replication: breaking the rules of the road causes genomic instability
- Genomic instability may be a signal of human embryonic stem cell differentiation
- The structure of conformational junctions in DNA and genomic instability
- Altered helical structures: Repair and induction of genomic instability
- Inflammation and genomic instability in murine hematopoietic system
- Epstein-Barr virus and genomic instability-a new look at the mechanisms of viral oncogenesis
- Role of Backup NHEJ Repair in Creating Genomic Instability in CML. Addendum
- Epigenetic Alterations in Radiation-Induced Genomic Instability
- Investigation of Genomic Instability in Clonal Descendants after X-ray Irradiation S. Zahnreich1, M. Durante1, 3, C. Fournier1, L. Melnikova2, E. Nasonova2, S …
- GENOMIC INSTABILITY IN PERIPHERAL BLOOD LYMPHOCYTES OF CANCER PRONE SYNDROMES
- Association of key antioxidants and their gene variants with prostate tumor genomic instability
- Radiation-induced Genomic Instability and Cellular Communication: Mechanistic Investigations
- Impact of chromosomal translocation and genomic instability on personalized medicine
- Genome-wide hypomethylation in HNSCC is more pronounced in HPV-negative tumors and is associated with genomic instability
- The Adaptive Response, Genetic Haplo-Insufficiency and Genomic Instability
- Role of thymidylate synthase in genomic instability and tumorigenesis.
- Evolutionary Comparison of the Mechanism of DNA Cleavage with Respect to Immune Diversity and Genomic Instability
- Genomic instability at late time after chronic radiation exposure
- Genomic study of familial breast cancer-genomic instability, classification and predisposition
- DNA Repair Deficient Cell Lines—Tools to Study Genomic Instability
- The regional genomic instability induced by 60Co γ-rays in B16 cells transfected by GFP
- Study on the relationship between DNA-PKcs and genomic instability and hyper-radiosensitivity
- The Role of Backup NHEJ Repair in Creating Genomic Instability in CML
- Defining risk factors for genomic instability in B cells: Novel insights from NGS-based technologies
- Genomic instability promoted by expression of human transposase-derived gene
- The common fragile site genes CNTLN and LINGO2 are associated with increased genomic instability in different tumors
- The role of SEPT9_v1 in breast cancer: Insights into the development of pro-oncogenic phenotypes and genomic instability
- Perturbation of Genomic Instability by Wortmannin in Myeloma.
- β-Catenin induces T-cell transformation by promoting genomic instability (HEM4P. 237)
- Reciprocal Regulation between DNA-PKcs and Snail1 Conferring Genomic Instability
- MITOTIC ANALYSIS AS A MEASURE OF GENOMIC INSTABILITY DURING THE PROPAGATION OF HUMAN PLURIPOTENT STEM CELLS
- Exploring the role of genomic instability in cancer and neurodegenerative disease through mouse models
- The Role of Lysosomes in Radiation Induced Genomic Instability
- Molecular Mechanisms Underlying Genomic Instability in Brca-Deficient Cells
- From DNA to Protein: a study of genomic instability candidate genes during zebrafish development
- DNA: RNA hybrid genome-wide profiling and links to genomic instability
- Somatic Variation and Genomic Instability Generated by Retrotransposons
- 80P Expression of Hormad1, A Cancer/Testis Antigen, In Triple-Negative Breast Cancers with High Genomic Instability
- Telomere-Mediated Genomic Instability and the Clinico-Pathological Parameters in Breast Cancer
- Genomic instability in induced stem cells and regulation of P14ARF expression
- Hypoxia causes down-regulation of Mismatch Repair System and genomic instability in Stem Cells
- The X chromosome: does it have a role in Bloom syndrome, a genomic instability disorder?
- Phenotypes of genomic instability in peripheral blood lymphocytes of greenhouse workers with exposure to pesticides.
- Loss of the Thioredoxin Reductase Trr1 Suppresses the Genomic Instability
- Mitochondrial Respiratory Chain Complex III Causes Genomic Instability In CML-CP.
- Loss of the RB tumor suppressor contributes to genomic instability
- Persistent dysregulation of DNA methylation in cells with arsenic-induced genomic instability
- The characterization of genomic instability in Schizosaccharomyces pombe cdc24 mutants
- e MMSET oncogene promotes telomere-induced genomic instability
- Vegetarians exhibit a low level of genomic instability
- Increased chemosensitivity of paclitaxel by telomeric fusion-induced genomic instability
- The effect of genomic instability on responsiveness to angiotensin II type 1 receptor stimulation and blockade
- Genomic instability in EBV-transformed lymphoblastoid cell lines
- Adaptive response and genomic instability: allosteric response of genome to negative impact
- Genomic instability of the breast tumor microenvironment: Stromal alterations or technological artifact
- Do Deregulated Cas Proteins Induce Genomic Instability in Early-Stage Ovarian Cancer
- Topographical analysis of telomere length and correlation with genomic instability in whole mount prostatectomies
- Lack of CK1δ increases DNA damage and genomic instability due to defects in DNA repair and mitotic checkpoints
- Interrelation of effects of genomic instability and restructuring of DNA methylation under chronic γ-irradiation
- Validation of expression of HORMAD1 protein, a cancer/testis antigen, in triple-negative breast cancers with high genomic instability
- Lack of checkpoint control in human pluripotent stem cells: a cause for genomic instability?
- A time course study of genomic instability in breast cancer patients receiving neoadjuvant therapy with or without bevacizumab
- Genomic instability and telomere characteristics as predictive biomarkers of therapeutic response in triple-negative breast cancer
- Colorectal carcinomas from Middle East. Molecular and tissue microarray analysis of genomic instability pathways
- Pim2 cooperates with PML-RARα to induce acute myeloid leukemia by enhancing genomic instability
- The oncogene Mdmx promotes genomic instability independent of p53.
- Chromatin dynamics and genomic instability during replicative aging
- Inflammatory mediator-induced bystander effects and genomic instability: role of tissue-specificity
- Genomic instability in freshly Epstein-Barr Virus (EBV)-infected B cells
- Cytosines, but not purines, determine RAG induced breaks on heteroduplex DNA structures: implications for genomic instability
- Genomic instability of the histone repeats in the Drosophila virilis group
- Ribonucleotide reductase promotes genomic instability and tumor heterogeneity via increasing dUTP misincorporation into DNA
- Genomic Instability Is Frequent in Oral and Rare in Nasal Mucosal Cells of Allogeneic HCT Recipients.
- Genomic instability in human breast epithelial cells induced by malathion and estrogen
- MECHANISMS OF V (D) J RECOMBINASE MEDIATED GENOMIC INSTABILITY AND LYMPHOMAGENESIS
- Male-specific cancers in Iceland: Family history, genomic instability and genetic predisposition
- Dysfunctional homologous recombination mediates genomic instability and progression in myeloma
- Overexpression of the DNA repair regulator PARI in pancreatic cancers promotes genomic instability and tumorigenesis.
- Genomic Instability from Loss of XPG, a BRCA1/2 Partner: Role in Ovarian Cancer?
- T315I Mutation INCREASES the GENOMIC Instability and the Mutator Phenotype IN BCR-ABL-Expressing LEUKEMIC CELLS.
- Genomic Instability in Common Fragile Sites (CFSs) Is Associated With Less Favorable Outcome in Patients With Intermediate-Risk Prostate Cancer (IR-CaP)
- Genomic Instability After Allogeneic HCT: Frequent in Oral and Rare in Nasal Mucosal Cells
- Telomere resolution and genomic instability in mouse embryonic stem cells
- Comparison of mortality and incidence cancer risk and models of genomic instability: the Techa River cohort
- Genomic Instability in CML-CP originates From the Most Primitive Imatinib-Refractory Leukemia Stem Cells
- Expression of a mutant succinate dehydrogenase subunit D and its role in superoxide production and genomic instability
- Research Upregulation of FOXM1 induces genomic instability in human epidermal keratinocytes
- The comparison of genomic instability between epidermal growth factor receptor (EGFR) mutation status of lung adenocarcinoma
- Increased Oxidative Stress and Genomic Instability in Peripheral Blood and Bone Marrow of Individuals with Fanconi Anemia
- Role of latent EBV genes in the induction of genomic instability in Burkitt s lymphoma
- The Bloom’s complex mousetrap: genomic instability often underlies cancer. Analyses of proteins implicated in a cancer-predisposing condition called Bloom’s …
- Genomic and epigenomic instability, fragile sites, schizophrenia and autism
- Dietary Restriction Improves Vasodilator Dysfunction Caused by Accelerated Vascular Aging Due to Genomic Instability
- Vitamin D has protective effects against cyclophosphamide-induced genomic instability in CHL cells in vitro and in mice in vivo
- The enhanced genomic instability was induced by alpha particle and low-energy ion irradiation in somatic cells of Arabidopsis thaliana
- Age Related Expression of hMLH1 but Not hMSH2 in Human Hematopoietic Stem Cells Predicts Genomic Instability.
- γH2AX as a marker of genomic instability predicts cisplatin sensitivity in triple negative breast cancer cells
- Replication stress and DNA damage promote genomic instability in near-tetraploid colorectal cancer cells
- Abstract# 1286: Genomic instability phenotype induced by loss of FancJ helicase function
- Overexpression of EVI1 Causes Genomic Instability and Cell Cycle Arrest in Hematopoietic Cells.
- Dietary restriction improves vasomotor changes caused by accelerated vascular aging due to genomic instability
- GRAPE SEED EXTRACT POLYPHENOLS AND CURCUMIN REDUCE GENOMIC INSTABILITY EVENTS IN A TRANSGENIC MOUSE MODEL FOR ALZHEIMER’S …
- Cytoskeletal defects lead to cytokinesis failure and genomic instability in cancer cells
- Radio-protective effect of cinnamic acid, a phenolic phytochemical, on genomic instability induced by X-rays in human blood lymphocytes in vitro
- Gastric cancer associated variant of DNA polymerase Beta (Leu22Pro) induce genomic instability and cellular transformation
- Role of gene tp53 in mechanism of transgenerational genomic instability under chronic exposure to radiation in small doses
- Induction of activation-induced cytidine deaminase (AID) by dendritic cells leads to genomic instability in human myeloma
- Response to Baverstock, K. Comments on Rithidech, KN; et al. Lack of Genomic Instability in Bone Marrow Cells of SCID Mice Exposed Whole-Body to Low-Dose …
- Mechanism Of RAG Action As A Structure-Specific Nuclease: Implications In Genomic Instability In Lymphoid Cells
- Telomerase-Mediated Repair of Induced DNA Breaks Leads to Increased Genomic Instability in Multiple Myeloma Cells: Possible Mechanism and …
- Deregulated EVI1 Expression Leads to Genomic Instability and G1 Cell Cycle Arrest
- ICAD deficiency in human colon cancer and predisposition to colon tumorigenesis in mice: Linkage to resistance to apoptosis and susceptibility to genomic instability
- Abstract# 4337: PCR-free approach detects high rate of genomic instability in prostate cancer
- Role of VHL in DNA double-strand break repair and genomic instability in renal cell carcinoma
- Escherichia coli induces DNA double strand breaks in gut cells and triggers genomic instability
- The Role of Lipoproteins/cholesterol in Genomic Instability and Chromosome Mis-segregation in Alzheimer’s and Cardiovascular Disease
- Genomic Instability after allogeneic HCT is frequent in oral and rare in nasal mucosal cells: effect of chronic GvHD?
- The Role of DNA Methylation Changes in Radiation-Induced Transgenerational Genomic Instability and Bystander Effects in cranial irradiated Mice
- Radiation-induced genomic instability in directly irradiated versus bystander Cho-K1 cells
- Identification of a predominant pattern of co-regulation among kinetochore genes; prospective regulatory elements, and association with genomic instability
- Abstract P5-02-03: Large-scale genomic instability consistently identifies BRCA1/2 inactivation in breast cancers
- The consequences of head-on replication-transcription conflicts on replication restart and genomic instability in Bacillus subtilis
- Prostate cancer health disparity in African American and Caucasian American men characterized through the landscape of genomic instability
- A next-generation sequencing approach reveals U-turn-like inversions as a major source of genomic instability in organelles of Arabidopsis and humans
- P1. 15 Phosphorylated HSP90A as a Biomarker for Genomic Instability and DNA Repair Inhibition
- Aberrant regulation of the DNA replication licensing system and genomic instability in penile squamous cell carcinoma
- The tumor suppressor gene Rb1 controls telomeric length and genomic instability that predisposes to osteosarcoma development in irradiated mice
- A cancer-associated DNA polymerase δ variant modeled in yeast causes a catastrophic increase in genomic instability
- Abstract# 1885: Genomic instability is not required for the acute transforming phenotype of c-Myc
- … Leukemia Stem Cells (LSCs) and Leukemia Progenitor Cells (LPCs) Display Overlapping and Unique Mechanisms of Genomic Instability: The Role of PI3k …
- 796 CORTISOL SERUM LEVELS ARE INCREASED AND INDUCE GENOMIC INSTABILITY IN ADVANCED PROSTATE CANCER
- Abstract IA18: Tumor suppressor gene silencing by somatic mutations and promoter methylation leads to genomic instability in head and neck squamous cell …
- Bystander effect and genomic instability in human cells and their progeny after irradiation with X rays, protons or carbon ions: role of gap junction communication
- Thymocyte selection-associated HMG box protein (TOX) induces genomic instability in T-cell acute lymphoblastic leukemia
- … Deacetylase Inhibitors Promote Abnormal Binding of DNA Repair Proteins to DNA Double Strand Breaks: Consequences for DNA Repair and Genomic Instability?.
- Genomic instability at the 13q31 locus and somatic mtDNA mutation in the D-loop site correlate with tumor aggressiveness in sporadic Brazilian breast cancer cases
- … at relapse in acute myeloid leukemia (AML) with FLT3 internal tandem duplication (ITD) and normal karyotype at diagnosis: Evidence for genomic instability?
- MP66-01 SPOP MUTATION LEADS TO GENOMIC INSTABILITY IN PROSTATE CANCER
- Abstract P3-04-04: Amplification and overexpression of TLK2 promote genomic instability in invasive breast cancer
- Wee1 deficiency in the mammary gland results in genomic instability and tumorigenesis by affecting cell cycle coordination and mitotic spindle morphogenesis
- RKIP-1 and the Cell Cycle: Novel Insight Into Genomic Instability
- Thymocyte Selection-Associated High-Mobility Group Box Protein (TOX) Induces Genomic Instability in T-Cell Acute Lymphoblastic Leukemia
- GENOMIC INSTABILITY AFTER ALLOGENEIC HEMATOPOIETIC CELL TRANSPLANTATION IS FREQUENT IN ORAL MUCOSA, PARTICULARLY IN PATIENTS …
- Abstract A2-13: Targeting genomic instability to identify molecular drivers of poor prognosis in cancer.
- Yeast Assay Highlights the Intrinsic Genomic Instability of Human PML Intron 6 over Intron 3 and the Role of Replication Fork Proteins
- Role Of Sirtuin-6 In Maintenance Of Genomic Instability In Multiple Myeloma Cells
- MTHFR Functional Polymorphism C677T and Genomic Instability in the Etiology of Idiopathic Autism in Simplex Families
- Microdeletions at Apparently Balanced Translocation Breakpoints Are Biomarkers for Heightened Genomic Instability in Patients with Non-MLL Acute Myeloid …
- Abstract P5-10-01: Clinical relevance of TP53 mutations and genomic instability in node positive breast cancer
- MTHFR Functional Polymorphism C677T and Genomic Instability in the Etiology of Idiopathic Autism in Simplex Families. Revision
- … FLT3/ITD Mutations Exhibit Elevated Repair Errors Generated through Alternative DNA Double Strand Break Repair Pathways: Implications for Genomic Instability.
- Abstract P4-14-01: A time course study of genomic instability in breast cancer patients receiving neoadjuvant therapy with or without bevacizumab
- Abstract# 2084: Smad4 deletion leads to spontaneous head and neck cancer formation associated with genomic instability
- Apurinic/Apyrimidinic Endonuclease 1 Induced Genomic Instability Causes T-Cell Acute Lymphoblastic Leukemia in Zebrafish
- Abstract# 3485: Correlations between telomere dysfunction and genomic instability in prostatic carcinogenesis
- … Defence Genes in Myelofibrosis and Related Neoplasms. Potential Implications of Downregulation of Nrf2 for Genomic Instability and Disease Progression
- Abstract B1-62: Bumphunting analysis identifies PAX5 promoter methylation and p53 somatic mutations in genomic instability pathways linked to very poor survival in …
- Instability of succinate dehydrogenase in SDHD polymorphism connects reactive oxygen species production to nuclear and mitochondrial genomic mutations in yeast
- Estrogens and genomic instability in human cancer cells-involvement of Src/Raf/Erk signaling in micronucleus formation by estrogenic chemicals
- Deletion of the Chromatin Remodeling Factor Brg1 Leads to Genomic Instability During Development, and Confers Sensitivity to Adult-onset Doxorubicin …
- Abstract# 788: Long-term exposure to Nano-TiO2 promotes genomic instability and cell transformation in mammalian cells
- Abstract# 1653: Expression of putative intestinal stem cell marker GPR49 and genomic instability in Barrett# 8217; s esophagus and associated adenocarcinoma
- P2-06-01: Genomic Instability in Breast Cancers from Atomic Bomb Survivors: An Analysis of Microarray-Comparative Genomic Hybridization with Old Archival Tissues …
- … : Nuclear architecture in human thyroid carcinoma revealed by three-dimensional (3D) telomere imaging: New insight into genomic instability and potential diagnostic …
- S. 85. Chronic GVHD Appears to Cause Genomic Instability in Oral Mucosal Cells After Allogeneic Hematopoeitic Cell Transplantation (HCT)
- … of chromosomal region 20q11. 21 provides a selective advantage in human ES cells-effects on growth, differentiation and further genomic instability
- Regulation of the Insulin-like Growth Factor 1-Secretory Clusterin Expression Axis in Genomic Instability and Cell Stress
- … bearing FLT3/ITD mutations exhibit elevated repair errors generated through alternative DNA double strand break repair pathways: implications for genomic instability …
- Inhibition of IGF-1 suppress genomic instability and epithelial lineage aberrations in the mammary gland of BRCA1 deficient mice
- Role of Nuclear Heme Oxygenase 1 (HO-1) in Bortezomib Induced Cell Death and Genomic Instability of Multiple Myeloma (MM) Cells
- … : Chapter 32. Developmental Disabilities, Autism, and Schizophrenia at a Single Locus: Complex Gene Regulation and Genomic Instability of 15q11–q13 …
- Abstract P2-04-05: Prolonged targeted overexpression of Aurora-A in mammary epithelium promotes mammary adenocarcinoma with genomic instability
- Genomic signatures of chromosomal instability and osteosarcoma progression detected by high resolution array CGH and interphase FISH
- Reducing MCM levels in human primary T cells during the [G. sub. 0][right arrow][G. sub. 1] transition causes genomic instability during the first cell cycle
- … assembly checkpoint adaptation, and tetraploidy arrest:: Implications for intrinsic and chemically induced genomic instability. Mutation Research/Fundamental …
- Radiation-induced hyperproliferation of intestinal crypts results in elevated genome instability with inactive p53-related genomic surveillance
- Association of survival and disease progression with chromosomal instability: a genomic exploration of colorectal cancer
- Identification of protein signatures of genomic stability/instability in epithelial cancers
- Genomic and epigenetic instability in colorectal cancer
- Amplicon, genomic background and genome instability in heterogeneous MYCN amplified neuroblastoma
- Dynamic instability of genomic methylation patterns in pluripotent stem cells
- Dynamic instability of the major urinary protein gene family revealed by genomic and phenotypic comparisons between C57 and 129 strain mice
- Genomic and epigenetic instability in chordoma: current insights
- Genomic view of factors leading to plaque instability
- Microsatellite instability in pediatric high grade glioma is associated with genomic profile and differential target gene inactivation
- Instability at the FRA8I common fragile site disrupts the genomic integrity of the KIAA0146, CEBPD and PRKDC genes in colorectal cancer
- Imidazopurinones are markers of physiological genomic damage linked to DNA instability and glyoxalase 1-associated tumour multidrug resistance
- A robust genomic signature for the detection of colorectal cancer patients with microsatellite instability phenotype and high mutation frequency
- Reversion of a fungal genetic code alteration links proteome instability with genomic and phenotypic diversification
- Low-frequency microsatellite instability in genomic di-nucleotide sequences correlates with lymphatic invasion and poor prognosis in gastric cancer
- Microsatellite Instability in Pediatric High Grade Glioma Is Associated with Genomic
- Genomic and Epigenetic Instability in Colorectal Cancer
- Genomic landscape of the Alzheimer’s disease brain: chromosome instability-aneuploidy, but not tetraploidy-mediates neurodegeneration
- Molecular pathogenesis of MDS: genomic and epigenetic instability
- Focal 9p instability in hematologic neoplasias revealed by comparative genomic hybridization and single‐nucleotide polymorphism microarray analyses
- Microsatellite Instability (MSI) as Genomic Marker in Endometrial Cancer: Toward Scientific Evidences
- Comprehensive genomic analysis provides further evidence that iron overload can induce genetic instability in myelodysplastic syndromes
- Microsatellite instability in pediatric high grade glioma is associated with genomic profile and differential target gene inactivation
- Development and validation of a genomic signature to identify colorectal cancer patients with microsatellite instability.
- Evolutionary hypothesis of telomere length in primary breast cancer and brain tumour patients: a tracer for genomic—tumour heterogeneity and instability
- Mathematical Modeling of a Metabolic Network to Study the Impact of Food Contaminants on Genomic Methylation and DNA Instability
- Genomic organization, rapid evolution and meiotic instability of nucleotide-binding-site-encoding genes in a new fruit crop,“chestnut rose”
- Genomic profiling of chromosomal instability in renal carcinoma primary cultures and cell lines by SNP array technology
- Compromised DNA Damage Repair Promotes Genetic Instability of the Genomic Magnetosome Island in Magnetospirillum magneticum AMB-1
- Genomic instability of iPSCs: challenges towards their clinical applications
- Nuclear genomic instability and aging
- Genomic instability in cancer: teetering on the limit of tolerance
- Mechanisms of genomic instability in breast cancer
- Endogenous DNA damage as a source of genomic instability in cancer
- Patterns of genomic instability in breast cancer
- Genomic instability of iPSCs and challenges in their clinical applications
- The presence of extra chromosomes leads to genomic instability
- Role of genomic instability in human carcinogenesis
- Sex differences in aging: genomic instability
- Genomic instability in the naturally and prematurely aged myocardium
- MYO10 drives genomic instability and inflammation in cancer
- Tumor hypoxia drives genomic instability
- ZSCAN10 expression corrects the genomic instability of iPSCs from aged donors
- DNA hypomethylation contributes to genomic instability and intestinal cancer initiation
- Genomic instability and metabolism in cancer
- Toward understanding genomic instability, mitochondrial dysfunction and aging
- Mitochondrial control of genomic instability in cancer
- Frequently mutated genes/pathways and genomic instability as prevention targets in liver cancer
- Complex DNA damage: a route to radiation-induced genomic instability and carcinogenesis
- Metformin: Prevention of genomic instability and cancer: A review
- miRNA dysregulation is an emerging modulator of genomic instability
- Chronic p53-independent p21 expression causes genomic instability by deregulating replication licensing
- Transcription dynamics prevent RNA-mediated genomic instability through SRPK2-dependent DDX23 phosphorylation
- Cyclin E deregulation and genomic instability
- High speed of fork progression induces DNA replication stress and genomic instability
- Mechanistic insights into KDM4A driven genomic instability
- Genomic instability and cancer risk associated with erroneous DNA repair
- Cribriform and intraductal prostate cancer are associated with increased genomic instability and distinct genomic alterations
- Global DNA hypomethylation in epithelial ovarian cancer: passive demethylation and association with genomic instability
- Genomic instability is induced by persistent proliferation of cells undergoing epithelial-to-mesenchymal transition
- The role of tumor microenvironment in genomic instability of malignant tumors
- Distinct DNA repair pathways cause genomic instability at alternative DNA structures
- Homing in on genomic instability as a therapeutic target in cancer
- Air pollution and genomic instability: The role of particulate matter in lung carcinogenesis
- Pan-Cancer Analysis of BRCA1 and BRCA2 Genomic Alterations and Their Association With Genomic Instability as Measured by Genome-Wide Loss of …
- Telomeres and genomic instability during early development
- Necessities in the processing of DNA double strand breaks and their effects on genomic instability and cancer
- Tools used to assay genomic instability in cancers and cancer meiomitosis
- Pan-cancer inference of intra-tumor heterogeneity reveals associations with different forms of genomic instability
- Genomic instability and cancer: lessons from Drosophila
- Transient genomic instability drives tumorigenesis through accelerated clonal evolution
- Female-biased embryonic death from inflammation induced by genomic instability
- Choices have consequences: the nexus between DNA repair pathways and genomic instability in cancer
- Cancer testis antigens and genomic instability: More than immunology
- Multiple molecular targets associated with genomic instability in lung cancer
- Fanconi anemia and the underlying causes of genomic instability
- cGAS suppresses genomic instability as a decelerator of replication forks
- The genomic health of human pluripotent stem cells: genomic instability and the consequences on nuclear organization
- Bad neighbours: hypoxia and genomic instability in prostate cancer
- Genomic instability in pancreatic adenocarcinoma: a new step towards precision medicine and novel therapeutic approaches
- Neutrophil-induced genomic instability impedes resolution of inflammation and wound healing
- Telomeres, reproductive aging, and genomic instability during early development
- Inflammation-associated genomic instability in cancer
- Bursting the bubble–nuclear envelope rupture as a path to genomic instability?
- A prostate cancer “nimbosus”: genomic instability and SChLAP1 dysregulation underpin aggression of intraductal and cribriform subpathologies
- Replication licensing aberrations, replication stress, and genomic instability
- Genomic instability signals offer diagnostic possibility in early cancer detection
- Combined MYC Activation and Pten Loss Are Sufficient to Create Genomic Instability and Lethal Metastatic Prostate Cancer
- Degradation of 5hmC-marked stalled replication forks by APE1 causes genomic instability
- Characterization of systemic genomic instability in budding yeast
- Catastrophic endgames: emerging mechanisms of telomere-driven genomic instability
- Exploiting MYC-induced PARPness to target genomic instability in multiple myeloma
- Sperm DNA damage causes genomic instability in early embryonic development
- DNA double-strand-break repair in higher eukaryotes and its role in genomic instability and cancer: Cell cycle and proliferation-dependent regulation
- Anaphase: a fortune-teller of genomic instability
- Perturbations in the replication program contribute to genomic instability in cancer
- Occupational exposure to anesthetics leads to genomic instability, cytotoxicity and proliferative changes
- Dysregulated APOBEC3G causes DNA damage and promotes genomic instability in multiple myeloma
- WWOX, the FRA16D gene: A target of and a contributor to genomic instability
- Genomic instability in mutant p53 cancer cells upon entotic engulfment
- p53 coordinates base excision repair to prevent genomic instability
- Genomic instability in human pluripotent stem cells arises from replicative stress and chromosome condensation defects
- Genomic instability in fungal plant pathogens
- Genomic instability in cancer: Molecular mechanisms and therapeutic potentials
- The dual roles of MYC in genomic instability and cancer chemoresistance
- Cyclin E/CDK2: DNA replication, replication stress and genomic instability
- R-loop proximity proteomics identifies a role of DDX41 in transcription-associated genomic instability
- Genomic instability in multiple myeloma
- R-loop-dependent replication and genomic instability in bacteria
- Whole chromosome loss and genomic instability in mouse embryos after CRISPR-Cas9 genome editing
- Genome-wide map of R-loop-induced damage reveals how a subset of R-loops contributes to genomic instability
- Single-cell circulating tumor cell analysis reveals genomic instability as a distinctive feature of aggressive prostate cancer
- Synergistic therapy of a naturally inspired Glycopolymer‐based biomimetic nanomedicine harnessing tumor genomic instability
- Identification of the prognostic significance of somatic mutation-derived LncRNA signatures of genomic instability in lung adenocarcinoma
- Global analysis of genomic instability caused by DNA replication stress in Saccharomyces cerevisiae
- G-quadruplex DNA drives genomic instability and represents a targetable molecular abnormality in ATRX-deficient malignant glioma
- Role of genomic instability in immunotherapy with checkpoint inhibitors
- G2/M-phase checkpoint adaptation and micronuclei formation as mechanisms that contribute to genomic instability in human cells
- CtIP-mediated fork protection synergizes with BRCA1 to suppress genomic instability upon DNA replication stress
- The replication stress response on a narrow path between genomic instability and inflammation
- Pharmacological effects and toxicogenetic impacts of omeprazole: genomic instability and cancer
- PARP inhibitors in clinical use induce genomic instability in normal human cells
- A study of meiomitosis and novel pathways of genomic instability in cutaneous T-cell lymphomas (CTCL)
- Genomic instability in circulating tumor cells
- Chromatin-associated MRN complex protects highly transcribing genes from genomic instability
- Oxidation of phosphorothioate DNA modifications leads to lethal genomic instability
- More than causing (epi) genomic instability: emerging physiological implications of transposable element modulation
- Genomic instability in adult men involved in processing electronic waste in Northern China
- Elevated glucose increases genomic instability by inhibiting nucleotide excision repair
- Mechanisms of oncogene-induced genomic instability
- Fluid shear stress impacts ovarian cancer cell viability, subcellular organization, and promotes genomic instability
- Chronic inflammation-associated genomic instability paves the way for human esophageal carcinogenesis
- Inherited mitochondrial genomic instability and chemical exposures
- Impaired DNA double-strand break repair contributes to the age-associated rise of genomic instability in humans
- Genomic instability and DNA damage repair pathways induced by human papillomaviruses
- Genomic instability and DNA replication defects in progeroid syndromes
- Mutational signatures reveal the role of RAD52 in p53-independent p21-driven genomic instability
- QNBC is associated with high genomic instability characterized by copy number alterations and miRNA deregulation
- Periodontitis: genomic instability implications and associated risk factors
- KHDC3L mutation causes recurrent pregnancy loss by inducing genomic instability of human early embryonic cells
- Loss of p53-mediated cell-cycle arrest, senescence and apoptosis promotes genomic instability and premature aging
- Temporal DNA-PK activation drives genomic instability and therapy resistance in glioma stem cells
- Elevated retrotransposon activity and genomic instability in primed pluripotent stem cells
- TOX regulates growth, DNA repair, and genomic instability in T-cell acute lymphoblastic leukemia
- Genomic instability and carcinogenesis of heavy charged particles radiation: Clinical and environmental implications
- The role of APC/CCdh1 in replication stress and origin of genomic instability
- ATM deficiency generating genomic instability sensitizes pancreatic ductal adenocarcinoma cells to therapy-induced DNA damage
- Predicting human genes susceptible to genomic instability associated with Alu/Alu-mediated rearrangements
- Induction of DNA damage and erroneous repair can explain genomic instability caused by endosulfan
- Ovarian Cancers Harboring Inactivating Mutations in CDK12 Display a Distinct Genomic Instability Pattern Characterized by Large Tandem Duplications
- MSL pushes genomic instability over the edge
- TGFβ promotes genomic instability after loss of RUNX3
- Association of genomic instability with HbA1c levels and medication in diabetic patients
- BRCA2 antagonizes classical and alternative nonhomologous end-joining to prevent gross genomic instability
- Elevated signature of a gene module coexpressed with CDC20 marks genomic instability in glioma
- Ectopic expression of testis germ cell proteins in cancer and its potential role in genomic instability
- Development and interpretation of a genomic instability derived lncRNAs based risk signature as a predictor of prognosis for clear cell renal cell carcinoma …
- Multiple signaling kinases target Mrc1 to prevent genomic instability triggered by transcription-replication conflicts
- Long noncoding RNA: A resident staff of genomic instability regulation in tumorigenesis
- ATM-deficiency increases genomic instability and metastatic potential in a mouse model of pancreatic cancer
- Obesity, oxidative DNA damage and vitamin D as predictors of genomic instability in children and adolescents
- Integrated analysis of the genomic instability of PTEN in clinically insignificant and significant prostate cancer
- Radiation-induced genomic instability, epigenetic mechanisms and the mitochondria: a dysfunctional ménage a trois?
- Transcribing malignancy: transcription-associated genomic instability in cancer
- Genomic instability of circulating tumor DNA as a prognostic marker for pancreatic cancer survival: a prospective cohort study
- Causes and consequences of genomic instability in laminopathies: Replication stress and interferon response
- Genomic instability of mutation-derived gene prognostic signatures for hepatocellular carcinoma
- Genomic instability as a main driving factor of unsuccessful ageing: potential for translating the use of micronuclei into clinical practice
- Geminin ablation in vivo enhances tumorigenesis through increased genomic instability
- Cytoplasmic accumulation of ELAVL1 is an independent predictor of biochemical recurrence associated with genomic instability in prostate cancer
- … for ionizing radiation and breast cancer involve direct and indirect DNA damage, oxidative stress, inflammation, genomic instability, and interaction with …
- Staining against phospho-H2AX (γ-H2AX) as a marker for DNA damage and genomic instability in cancer tissues and cells
- Clonal chromosomal and genomic instability during human multipotent mesenchymal stromal cells long-term culture
- Genomic instability in people living with HIV
- Independent mechanisms lead to genomic instability in Hodgkin lymphoma: Microsatellite or chromosomal instability
- ATM pathway activation limits R-loop-associated genomic instability in Werner syndrome cells
- Associations between circulating carotenoids, genomic instability and the risk of high‐grade prostate cancer
- Science in focus: genomic instability and its implications for clinical cancer care
- Genomic instability and innate immune responses to self-DNA in progeria
- Genomic instability promoted by overexpression of mismatch repair factors in yeast: a model for understanding cancer progression
- Germline risk contribution to genomic instability in multiple myeloma
- CTCF prevents genomic instability by promoting homologous recombination-directed DNA double-strand break repair
- Genomic instability associated with p53 knockdown in the generation of Huntington’s disease human induced pluripotent stem cells
- Chronic polycyclic aromatic hydrocarbon exposure causes DNA damage and genomic instability in lung epithelial cells
- A Case Study of Genomic Instability in an Industrial Strain of Saccharomyces cerevisiae
- Cadmium-induced genomic instability in Arabidopsis: Molecular toxicological biomarkers for early diagnosis of cadmium stress
- Dysregulation of DNA methylation induced by past arsenic treatment causes persistent genomic instability in mammalian cells
- Premature mitotic entry induced by ATR inhibition potentiates olaparib inhibition‐mediated genomic instability, inflammatory signaling, and cytotoxicity in BRCA2 …
- Replication stress, genomic instability, and replication timing: A complex relationship
- Mitochondrial reactive oxygen species-mediated genomic instability in low-dose irradiated human cells through nuclear retention of cyclin D1
- Prediction of bladder cancer outcome by identifying and validating a mutation-derived genomic instability-associated long noncoding RNA (lncRNA) signature
- Carbon content in airway macrophages and genomic instability in Chinese carbon black packers
- hnRNP H/F drive RNA G-quadruplex-mediated translation linked to genomic instability and therapy resistance in glioblastoma
- The EZH2–PHACTR2–AS1–ribosome axis induces genomic instability and promotes growth and metastasis in breast cancer
- Phosphatidylinositol 3-kinase δ blockade increases genomic instability in B cells
- The H3. 3K27M oncohistone affects replication stress outcome and provokes genomic instability in pediatric glioma
- R-loops cause genomic instability in T helper lymphocytes from patients with Wiskott-Aldrich syndrome
- Tumors overexpressing RNF168 show altered DNA repair and responses to genotoxic treatments, genomic instability and resistance to proteotoxic stress
- SPOP promotes transcriptional expression of DNA repair and replication factors to prevent replication stress and genomic instability
- Parental gamma irradiation induces reprotoxic effects accompanied by genomic instability in zebrafish (Danio rerio) embryos
- SETD2 Haploinsufficiency for Microtubule Methylation Is an Early Driver of Genomic Instability in Renal Cell Carcinoma
- TP53 mutation-mediated genomic instability induces the evolution of chemoresistance and recurrence in epithelial ovarian cancer
- Estimation of genomic instability and mutation induction by graphene oxide nanoparticles in mice liver and brain tissues
- Induction of genomic instability and activation of autophagy in artificial human aneuploid cells
- Overexpression of the base excision repair NTHL1 glycosylase causes genomic instability and early cellular hallmarks of cancer
- Understanding how genetic mutations collaborate with genomic instability in cancer
- Locked in a vicious cycle: the connection between genomic instability and a loss of protein homeostasis
- Genomic instability during reprogramming by nuclear transfer is DNA replication dependent
- Genomic instability-associated lncRNA signature predicts prognosis and distinct immune landscape in gastric cancer
- Lingering questions about enhancer RNA and enhancer transcription-coupled genomic instability
- Genomic instability in fragile sites—still adding the pieces
- Genomic instability-derived plasma extracellular vesicle-microRNA signature as a minimally invasive predictor of risk and unfavorable prognosis in breast …
- Maf1‐dependent transcriptional regulation of tRNAs prevents genomic instability and is associated with extended lifespan
- A fast and reliable method for monitoring genomic instability in the model organism Caenorhabditis elegans
- Cep55 overexpression promotes genomic instability and tumorigenesis in mice
- Bioinformatic identification of genomic instability-associated lncRNAs signatures for improving the clinical outcome of cervical cancer by a prognostic model
- Prostate cancer-associated SPOP mutations lead to genomic instability through disruption of the SPOP–HIPK2 axis
- Environmental exposure to mineral coal and by-products: influence on human health and genomic instability
- Loss of G9a preserves mutation patterns but increases chromatin accessibility, genomic instability and aggressiveness in skin tumours
- Genomic instability and cellular senescence: Lessons from the budding yeast
- Drug targeting of genomic instability in multiple myeloma
- CRL4ADTL degrades DNA-PKcs to modulate NHEJ repair and induce genomic instability and subsequent malignant transformation
- Regional signals in the planarian body guide stem cell fate in the presence of genomic instability
- Genomic instability in chronic obstructive pulmonary disease and lung cancer: A systematic review and meta-analysis of studies using the micronucleus assay
- The NEIL1 G83D germline DNA glycosylase variant induces genomic instability and cellular transformation
- Frequency of the TP53 R337H variant in sporadic breast cancer and its impact on genomic instability
- Crucial role of the C-terminal domain of Hfq protein in genomic instability
- PLOD3 is associated with immune cell infiltration and genomic instability in colon adenocarcinoma
- Genomic instability at the locus of sterol C24-methyltransferase promotes amphotericin B resistance in Leishmania parasites
- Assessment of genomic instability in medical workers exposed to chronic low-dose X-Rays in Northern China
- Genomic instability signature of palindromic non-coding somatic mutations in bladder cancer
- 53BP1 loss rescues embryonic lethality but not genomic instability of BRCA1 total knockout mice
- Loss of the transforming growth factor‐β effector β2‐Spectrin promotes genomic instability
- Mycobacterium tuberculosis EsxO (Rv2346c) promotes bacillary survival by inducing oxidative stress mediated genomic instability in macrophages
- Catalytically inactive Cas9 impairs DNA replication fork progression to induce focal genomic instability
- Translesion synthesis or repair by specialized dna polymerases limits excessive genomic instability upon replication stress
- Uranium induces genomic instability and slows cell cycle progression in human lymphocytes in acute toxicity study
- Polycomb repressor complex 2 in genomic instability and cancer
- … TPX2 suppresses the tumorigenesis of hepatocellular carcinoma cells resulting in arrested mitotic phase progression and increased genomic instability
- Double strand breaks (DSBs) as indicators of genomic instability in PATRR-mediated translocations
- Hydrogen peroxide, a potent inducer of global genomic instability
- Increased levels of genomic instability and mutations in homologous recombination genes in locally advanced rectal carcinomas
- Histone H3G34R mutation causes replication stress, homologous recombination defects and genomic instability in S. pombe
- Survival outcomes are associated with genomic instability in luminal breast cancers
- FBXO31 protects against genomic instability by capping FOXM1 levels at the G2/M transition
- Comprehensive analyses identify APOBEC3A as a genomic instability-associated immune prognostic biomarker in ovarian cancer
- Dystrophin deficiency leads to genomic instability in human pluripotent stem cells via NO synthase-induced oxidative stress
- … -AS1 promotes paclitaxel resistance in triple negative breast cancer by regulation of miR-26a-5p/MTDH pathway-mediated autophagy and genomic instability
- Using telomeric chromosomal aberrations to evaluate clastogen-induced genomic instability in mammalian cells
- Sunitinib induces genomic instability of renal carcinoma cells through affecting the interaction of LC3-II and PARP-1
- Pyruvate kinase M2 phosphorylates H2AX and promotes genomic instability in human tumor cells
- Separase prevents genomic instability by controlling replication fork speed
- A signature of genomic instability resulting from deficient replication licensing
- Prognostic immunity and therapeutic sensitivity analyses based on differential genomic instability-associated lncRNAs in left-and right-sided colon …
- … of arsenic induced toxicity based on arsenic accumulation, translocation and its implications on physio-chemical changes and genomic instability in indica rice (Oryza …
- Constitutive aneuploidy and genomic instability in the single‐celled eukaryote Giardia intestinalis
- Amplification of TLK2 Induces Genomic Instability via Impairing the G2–M Checkpoint
- Cancer and Genomic Instability
- Chromatin remodeller SMARCA4 recruits topoisomerase 1 and suppresses transcription-associated genomic instability
- Expression of genomic instability-related molecules: cyclin F, RRM2 and SPDL1 and their prognostic significance in pancreatic adenocarcinoma
- Genomic instability induced in distant progeny of bystander cells depends on the connexins expressed in the irradiated cells
- Genomic instability and proliferation/survival pathways in RB1-deficient malignancies
- Genomic instability in lower-grade glioma: Prediction of prognosis based on lncRNA and immune infiltration
- Checkpoint defects elicit a WRNIP1-mediated response to counteract R-loop-associated genomic instability
- TCR clonality and genomic instability signatures as prognostic biomarkers in high grade serous ovarian cancer
- … tumours of the uterus and ovaries with Mullerian and germ cell or trophoblastic components have a somatic origin and are characterised by genomic instability
- The frequencies of micronuclei, nucleoplasmic bridges and nuclear buds as biomarkers of genomic instability in patients with urothelial cell carcinoma
- … -and-see treatment strategy could be considered for lung adenocarcinoma with special pleural dissemination lesions, and low genomic instability correlates with better …
- Modeling genomic instability and selection pressure in a mouse model of melanoma
- Epstein–Barr virus BRLF1 induces genomic instability and progressive malignancy in nasopharyngeal carcinoma cells
- Progressing from recurring tissue injury to genomic instability: a new mechanism of neutrophil pathogenesis
- Genomic instability and cytotoxicity in buccal mucosal cells of workers in banana farming evaluated by micronucleus test
- Genomic instability is a principle pathologic feature of FLT3 ITD kinase activity in acute myeloid leukemia leading to clonal evolution and disease progression
- Toxicogenetic study of Persea americana fruit pulp oil and its effect on genomic instability
- 271 Comparison of genomic instability test scores used for predicting PARP activity in ovarian cancer
- Infection with genotoxin‐producing Salmonella enterica synergises with loss of the tumour suppressor APC in promoting genomic instability via the PI3K pathway in …
- Heme oxygenase-1 nuclear translocation regulates bortezomib-induced cytotoxicity and mediates genomic instability in myeloma cells
- ER stress and genomic instability induced by gamma radiation in mice primary cultured glial cells
- 53 BP 1 ablation rescues genomic instability in mice expressing ‘RING‐less’ BRCA 1
- … the diversity of mating mechanisms in Saccharomyces cerevisiae x Saccharomyces kudriavzevii hybrids, and the genomic instability that promotes phenotypic …
- Genomic instability in exfoliated buccal cells among cement warehouse workers
- Estimation of genomic instability and DNA methylation due to aluminum (Al) stress in wheat (Triticum aestivum L.) using iPBS and CRED-iPBS analyses
- Genomic instability is an early event in aluminium-induced tumorigenesis
- Kynurenine signaling increases DNA polymerase kappa expression and promotes genomic instability in glioblastoma cells
- Transcriptome analysis of pterygium and pinguecula reveals evidence of genomic instability associated with chronic inflammation
- Alternative non-homologous end joining repair: A master regulator of genomic instability in cancer
- Loss of p27kip1 increases genomic instability and induces radio-resistance in luminal breast cancer cells
- YM155 and BIRC5 downregulation induce genomic instability via autophagy-mediated ROS production and inhibition in DNA repair
- cAMP-mediated regulation of melanocyte genomic instability: A melanoma-preventive strategy
- Frailty syndrome and genomic instability in older adults: suitability of the cytome micronucleus assay as a diagnostic tool
- Nitric oxide alleviates the effects of copper-induced DNA methylation, genomic instability, LTR retrotransposon polymorphism and enzyme activity in lettuce
- Transient endoreplication down-regulates the kinesin-14 HSET and contributes to genomic instability
- Genomic instability in an interspecific hybrid of the genus Saccharomyces: A matter of adaptability
- FANCD2 limits acetaldehyde‐induced genomic instability during DNA replication in esophageal keratinocytes
- Tying up loose ends: telomeres, genomic instability and lamins
- miR-155 overexpression promotes genomic instability by reducing high-fidelity polymerase delta expression and activating error-prone DSB repair
- Mycobacterium tuberculosis promotes genomic instability in macrophages
- A Novel Model Based on Genomic Instability-Associated Long Non-Coding RNAs for Predicting Prognosis and Response to Immunotherapy in Patients With …
- Identification of a somatic mutation-derived long non-coding RNA signatures of genomic instability in renal cell carcinoma
- Genomic Instability-Related LncRNA Signature Predicts the Prognosis and Highlights LINC01614 Is a Tumor Microenvironment-Related Oncogenic lncRNA …
- The miR-205-5p/BRCA1/RAD17 axis promotes genomic instability in head and neck squamous cell carcinomas
- Genomic instability and clonal evolution in chronic lymphocytic leukemia: clinical relevance
- DMBA promotes ErbB2‑mediated carcinogenesis via ErbB2 and estrogen receptor pathway activation and genomic instability
- Overall tumor genomic instability: an important predictor of recurrence-free survival in patients with localized clear cell renal cell carcinoma
- Short tandem repeats, segmental duplications, gene deletion, and genomic instability in a rapidly diversified immune gene family
- LINE‐ and Alu‐containing genomic instability hotspot at 16q24.1 associated with recurrent and nonrecurrent CNV deletions causative for ACDMPV
- Protective role of humic acids against picloram-induced genomic instability and DNA methylation in Phaseolus vulgaris
- Role of the antioxidant defence system and telomerase in arsenic-induced genomic instability
- LINE‐1 hypomethylation is associated with radiation‐induced genomic instability in industrial radiographers
- Peripheral blood lymphocytes as in vitro model to evaluate genomic instability caused by low dose radiation
- Dietary riboflavin deficiency induces genomic instability of esophageal squamous cells that is associated with gut microbiota dysbiosis in rats
- Deletion of Topoisomerase 1 in excitatory neurons causes genomic instability and early onset neurodegeneration
- Rint1 inactivation triggers genomic instability, ER stress and autophagy inhibition in the brain
- Genomic instability and replicative stress in multiple myeloma: the final curtain?
- Affected chromosome homeostasis and genomic instability of clonal yeast cultures
- Increasing genomic instability during cancer therapy in a patient with Li-Fraumeni syndrome
- Tumor evolution and therapeutic choice seen through a prism of circulating tumor cell genomic instability
- “Doubled-haploid” allohexaploid Brassica lines lose fertility and viability and accumulate genetic variation due to genomic instability
- Global analysis of furfural-induced genomic instability using a yeast model
- Ruthenium (II) complexes with N, O-chelating proline and threonine ligands cause selective cytotoxicity by the induction of genomic instability, cell cycle arrest and …
- DNA mismatch repair deficiency promotes genomic instability in a subset of papillary thyroid cancers
- Interleukin 6–dependent genomic instability heralds accelerated carcinogenesis following liver regeneration on a background of chronic hepatitis
- Mitotic errors promote genomic instability and leukemia in a novel mouse model of Fanconi anemia
- Rif1 and Exo1 regulate the genomic instability following telomere losses
- FANCJ compensates for RAP80 deficiency and suppresses genomic instability induced by interstrand cross-links
- Phyllanthus emblica Fruit Extract Activates Spindle Assembly Checkpoint, Prevents Mitotic Aberrations and Genomic Instability in Human Colon Epithelial NCM460 …
- Joint single cell DNA-Seq and RNA-Seq of cancer reveals subclonal signatures of genomic instability and gene expression
- Integrin-linked-kinase overexpression is implicated in mechanisms of genomic instability in human colorectal cancer
- Elucidating the genetic architecture underlying IGF1 levels and its impact on genomic instability and cancer risk
- Hepatitis C virus-cross-reactive TCR gene-modified T cells: a model for immunotherapy against diseases with genomic instability
- The use of murine models for studying mechanistic insights of genomic instability in multiple myeloma
- miR-18a reactivates the Epstein-Barr virus through defective DNA damage response and promotes genomic instability in EBV-associated lymphomas
- Electromagnetic fields, genomic instability and cancer: a systems biological view
- Smoking index, lifestyle factors, and genomic instability assessed by single-cell gel electrophoresis: a cross-sectional study in subjects from Yucatan, Mexico
- … of chemo-immune resistance by a TDO2-targeted Pt (IV) prodrug via attenuating endogenous Kyn-AhR-AQP4 metabolic circuity and TLS-promoted genomic instability
- Prevention of mitochondrial genomic instability in yeast by the mitochondrial recombinase Mhr1
- Chronic exposure to lead and cadmium pollution results in genomic instability in a model biomonitor species (Apodemus flavicollis Melchior, 1834)
- Investigation of belinostat-induced genomic instability by molecular cytogenetic analysis and pathway-focused gene expression profiling
- HIV Nef enhances the expression of oncogenic c-MYC and activation-induced cytidine deaminase in Burkitt lymphoma cells, promoting genomic instability
- Aberrant levels of SUV39H1 and SUV39H2 methyltransferase are associated with genomic instability in chronic lymphocytic leukemia
- Aberrant (pro) renin receptor expression induces genomic instability in pancreatic ductal adenocarcinoma through upregulation of SMARCA5/SNF2H
- Assessment of genomic instability and proliferation index in cultured lymphocytes of patients with Down syndrome, congenital anomalies and aplastic anaemia
- Anti-hyperlipidemic effects of Campomanesia xanthocarpa aqueous extract and its modulation on oxidative stress and genomic instability in Wistar rats
- … ‐Diamond syndrome with clonal interstitial deletion of the long arm of chromosome 20 in bone marrow: haematological features, prognosis and genomic instability
- MYBL2-driven transcriptional programs link replication stress and error-prone DNA repair with genomic instability in lung adenocarcinoma
- Identification of Mutator-Derived Alternative Splicing Signatures of Genomic Instability for Improving the Clinical Outcome of Cholangiocarcinoma
- Higher incidence of B cell malignancies in primary immunodeficiencies: a combination of intrinsic genomic instability and exocytosis defects at the …
- Mdm2 overexpression and p73 loss exacerbate genomic instability and dampen apoptosis, resulting in B-cell lymphoma
- Aberrant MCM10 SUMOylation induces genomic instability mediated by a genetic variant associated with survival of esophageal squamous cell carcinoma
- Mathematical modelling the pathway of genomic instability in lung cancer
- Humic acids protective activity against manganese induced LTR (long terminal repeat) retrotransposon polymorphism and genomic instability effects in Zea …
- Ddx19 links mRNA nuclear export with progression of transcription and replication and suppresses genomic instability upon DNA damage in proliferating cells
- Aberrant kynurenine signaling modulates DNA replication stress factors and promotes genomic instability in gliomas
- Thermodynamic energetics underlying genomic instability and whole-genome doubling in cancer
- IRX5 prompts genomic instability in colorectal cancer cells
- A novel ATM‐dependent checkpoint defect distinct from loss of function mutation promotes genomic instability in melanoma
- Induction of genomic instability in a primary human fibroblast cell line following low-dose alpha-particle exposure and the potential role of exosomes
- Primary and secondary bystander effect and genomic instability in cells exposed to high and low linear energy transfer radiations
- Spatial UBE2N protein expression indicates genomic instability in colorectal cancers
- Increased genomic instability following treatment with direct acting anti-hepatitis C virus drugs
- Persistent increased frequency of genomic instability in women diagnosed with breast cancer: before, during, and after treatments
- Telomere elongation through hTERT immortalization leads to chromosome repositioning in control cells and genomic instability in Hutchinson‐Gilford progeria …
- Systematic Analysis of the Stress-Induced Genomic Instability of Type Three Secretion System in Aeromonas salmonicida subsp. salmonicida
- A hypothesis to explain how the DNA of elderly people is prone to damage: genome-wide hypomethylation drives genomic instability in the elderly by …
- Cancer‐associated mutations in the condensin II subunit CAPH2 cause genomic instability through telomere dysfunction and anaphase chromosome bridges
- Extract of bulbus Fritillaria cirrhosa perturbs spindle assembly checkpoint, induces mitotic aberrations and genomic instability in human colon epithelial cell line
- Sister chromatid exchange and genomic instability in soft tissue sarcomas: Potential implications for response to DNA-damaging treatments
- Programmed genomic instability regulates neural transdifferentiation of human brain microvascular pericytes
- Genomic instability during aging of postmitotic mammalian cells
- Cancer and genomic instability
- Absence of cyclin-dependent kinase inhibitor p27 or p18 increases efficiency of iPSC generation without induction of iPSC genomic instability
- Hsp90 induces increased genomic instability toward DNA-damaging agents by tuning down RAD53 transcription
- Loss of dystroglycan drives cellular senescence via defective mitosis-mediated genomic instability
- Aggressive morphologic variants of mantle cell lymphoma characterized with high genomic instability showing frequent chromothripsis, CDKN2A/B loss, and TP53 …
- Genomic instability and aging: causes and consequences
- Lack of casein kinase 1 delta promotes genomic instability-the accumulation of dna damage and down-regulation of checkpoint kinase 1
- Genomic Instability in Stem Cells: The Basic Issues
- Estimation of low-dose radiation-responsive proteins in the absence of genomic instability in normal human fibroblast cells
- Genetic profile of GNAQ-mutated blue melanocytic neoplasms reveals mutations in genes linked to genomic instability and the PI3K pathway
- Age dependence of radiation-induced genomic instability in mouse hematopoietic stem cells
- Histone demethylase JARID1C inactivation triggers genomic instability in sporadic renal cancer
- Functional deficiency of DNA repair gene EXO5 results in androgen-induced genomic instability and prostate tumorigenesis
- Early, on-treatment levels and dynamic changes of genomic instability in circulating tumor DNA predict response to treatment and outcome in metastatic breast cancer …
- … a comprehensive view of 8-oxo-7, 8-dihydro-2′-deoxyguanosine: Highlighting the intertwined roles of DNA damage and epigenetics in genomic instability
- A genomic instability-derived risk index predicts clinical outcome and immunotherapy response for clear cell renal cell carcinoma
- Mechanisms of glycosylase induced genomic instability
- A bacterial genotoxin causes virus reactivation and genomic instability in Epstein–Barr virus infected epithelial cells pointing to a role of co‐infection in viral …
- Chromosomal Abnormalities: A Hallmark Manifestation of Genomic Instability
- Functional Inactivation of Drosophila GCK Orthologs Causes Genomic Instability and Oxidative Stress in a Fly Model of MODY-2
- Estimation of genomic instability and mitochondrial DNA damage induction by acute oral administration of calcium hydroxide normal-and nano-particles in mice
- Genomic instability in the brain: chromosomal mosaicism in schizophrenia
- MicroRNA-34a promotes genomic instability by a broad suppression of genome maintenance mechanisms downstream of the oncogene KSHV-vGPCR
- Genomic instability profiles at the single cell level in mouse colorectal cancers of defined genotypes
- Reduction in replication‐independent endogenous DNA double‐strand breaks promotes genomic instability during chronological aging in yeast
- The presence of genomic instability in cerebrospinal fluid in patients with meningeal metastasis
- Helicase-like transcription factor is a RUNX1 target whose downregulation promotes genomic instability and correlates with complex cytogenetic features in …
- Lack of superoxide dismutase in a rad51 mutant exacerbates genomic instability and oxidative stress-mediated cytotoxicity in Saccharomyces cerevisiae
- 3D Telomere Structure Analysis to Detect Genomic Instability and Cytogenetic Evolution in Myelodysplastic Syndromes
- PIGN gene expression aberration is associated with genomic instability and leukemic progression in acute myeloid leukemia with myelodysplastic features
- SEI1 induces genomic instability by inhibiting DNA damage response in ovarian cancer
- … and acute myeloid leukemia intermediated by “occult” myelodysplastic neoplasm: two cases of adult patients with evidence of genomic instability and clonal selection …
- Endoscopic ablation is a cost-effective cancer preventative therapy in patients with Barrett’s esophagus who have elevated genomic instability
- Assessment of genotoxicity and genomic instability in rat primary astrocytes exposed to 872 MHz radiofrequency radiation and chemicals
- RNF8 dysregulation and down-regulation during HTLV-1 infection promote genomic instability in adult T-cell leukemia
- Dynamics of replication proteins during lagging strand synthesis: a crossroads for genomic instability and cancer
- Inefficient differentiation response to cell cycle stress leads to genomic instability and malignant progression of squamous carcinoma cells
- Genomic instability and shared mechanisms for gene diversification in two distant immune gene families: the plant NBS-LRR genes and the Echinoid 185/333 genes
- Comet and cytogenetic tests as tools for evaluating genomic instability in seeds of Oryza sativa L. and Phaseolus vulgaris L. from gene banks
- Detection of impaired DNA replication and repair in micronuclei as indicators of genomic instability and chromothripsis
- Genomic instability in multiple myeloma: A “non-coding rna” perspective
- Clinical outcomes associated with pathogenic genomic instability mutations in prostate cancer: a retrospective analysis of US pharmacy and medical claims data
- Characterization of a clival chordoma xenograft model reveals tumor genomic instability
- Identification of mutator-derived lncRNA signatures of genomic instability for promoting the clinical outcome in hepatocellular carcinoma
- MCM4 is a novel biomarker associated with genomic instability, BRCAness phenotype, and therapeutic potentials in soft-tissue sarcoma
- Breast cancer and paradigm of genomic instability
- Predisposed genomic instability in pre-treatment bone marrow evolves to therapy-related myeloid neoplasms in malignant lymphoma
- Low E2F2 activity is associated with high genomic instability and PARPi resistance
- Chromatin and genomic instability in cancer
- A 17-marker panel for global genomic instability in breast cancer
- IL-17-mediated inflammation promotes cigarette smoke-induced genomic instability
- TDP2 suppresses genomic instability induced by androgens in the epithelial cells of prostate glands
- Genomic instability and aging: Causes and consequences
- Heat shock drives genomic instability and phenotypic variations in yeast
- Replication stress and FOXM1 drive radiation induced genomic instability and cell transformation
- Abnormal RNA splicing and genomic instability after induction of DNMT3A mutations by CRISPR/Cas9 gene editing
- Structural maturation of HIV-1 reverse transcriptase—a metamorphic solution to genomic instability
- Patterns of genomic instability in interspecific yeast hybrids with diverse ancestries
- Genomic instability in a chronic lymphocytic leukemia patient with mono-allelic deletion of the DLEU and RB1 genes
- Inactivation of parkin by promoter methylation correlated with lymph node metastasis and genomic instability in nasopharyngeal carcinoma
- MED28 over-expression shortens the cell cycle and induces genomic instability
- Genomic instability and DNA repair in cancer
- The role of oncogenic tyrosine kinase NPM-ALK in genomic instability
- Review of how genetic research on segmental progeroid syndromes has documented genomic instability as a hallmark of aging but let us now Pursue Antigeroid …
- Genomic instability in Buccal mucosal cells of children living in abnormal conditions from Santos-Sao Vicente Estuary
- A somatic mutation-derived LncRNA signature of genomic instability predicts prognosis for patients with liver cancer
- … (PTC) Harboring the AGK-BRAF and RET/PTC3 Fusion in a Mutually Exclusive Pattern Reveals Distinct Levels of Genomic Instability and Nuclear Organization
- DNA damage and genomic instability among workers formerly and currently exposed to asbestos
- A novel diagnostic method for thyroid follicular tumors based on immunofluorescence analysis of p53-binding protein 1 expression: Detection of genomic instability
- Genomic instability related to zinc deficiency and excess in an in vitro model: is the upper estimate of the physiological requirements recommended for children safe?
- Effect of diets, familial history, and alternative therapies on genomic instability of breast cancer patients
- p53-TP53-induced glycolysis regulator mediated glycolytic suppression attenuates DNA damage and genomic instability in fanconi anemia hematopoietic stem cells
- Expression pattern of p53-binding protein 1 as a new molecular indicator of genomic instability in bladder urothelial carcinoma
- Genomic Instability Promotes the Progression of Clear Cell Renal Cell Carcinoma Through Influencing the Immune Microenvironment
- 4-Hydroxy estrogen metabolite, causing genomic instability by attenuating the function of spindle-assembly checkpoint, can serve as a biomarker for breast …
- R-loops cause genomic instability in Wiskott-Aldrich syndrome Thelper lymphocytes
- Usnic acid attenuates genomic instability in Chinese hamster ovary (CHO) cells as well as chemical-induced preneoplastic lesions in rat colon
- The role of telomerase in radiation-induced genomic instability
- Calculated identification of mutator-derived lncRNA signatures of genomic instability to predict the clinical outcome of muscle-invasive bladder cancer
- 428 Genomic instability metric concordance between oncoscan™, cytosnp and an fda-approved HRD test
- Pim kinase inhibitor co-treatment decreases alternative non-homologous end-joining DNA repair and genomic instability induced by topoisomerase 2 …
- Association between p53-binding protein 1 expression and genomic instability in oncocytic follicular adenoma of the thyroid
- Radiation‐induced genomic instability in breast carcinomas of the Swedish hemangioma cohort
- Genomic instability in peripheral blood and buccal mucosal cells of marijuana smokers: The impact of tobacco smoke
- Genomic instability of pluripotent stem cells: origin and consequences
- Genetic predisposition to mosaic Y chromosome loss in blood is associated with genomic instability in other tissues and susceptibility to non-haematological cancers
- Study the impact of astaxanthin on developing of genomic instability in human peripheral blood lymphocytes irradiated in vitro on G2 phase of cell cycle.
- Pomegranate intake protects against genomic instability induced by medical X-rays in vivo in mice
- Genomic Instability Decreases in HIV Patient by Complementary Therapy with Rosmarinus officinalis Extracts
- The effect of pioglitazone on genomic instability in induced diabetic rats
- Titanium dioxide nanofibers induce angiogenic markers and genomic instability in lung cells leading to a highly dedifferentiated and fibrotic tumor formation in a …
- SATB1, genomic instability and Gleason grading constitute a novel risk score for prostate cancer
- Gnal haploinsufficiency causes genomic instability and increased sensitivity to haloperidol
- Genomic Instability and Cyto-Genotoxic Damage in Animal Species
- Correction: Dietary riboflavin deficiency induces genomic instability of esophageal squamous cells that is associated with gut microbiota dysbiosis in rats
- Elevated somatic mutation and evidence of genomic instability in veterans with Gulf War illness
- Low-dose chemotherapeutic drugs induce reactive oxygen species and initiate apoptosis-mediated genomic instability
- Genomic instability in buccal mucosal cells of municipal street sweepers as evaluated by micronucleus test
- Genomic instability and the spectrum of response to low radiation doses
- Noncanonical mismatch repair as a source of genomic instability in human cells
- Genomic Instability in Cancer II: 4N-Skewed (90) Reductive Division via Fragile Sites to Fitness Increase for Solid and Hematological Cancer Beginnings
- Particulate Matter Exposure: Genomic Instability, Disease, and Cancer Risk
- Cell plasticity and genomic instability in cancer evolution
- Possible radioprotective effect of folic acid supplementation on low dose ionizing radiation-induced genomic instability in vitro
- Deeper insight in metastatic cancer progression; epithelial-to-mesenchymal transition and genomic instability: Implications on treatment resistance
- Nuclear and cytoplasmatic abnormalities as a tools for evaluating genomic instability
- Protective effect of β-D-glucan and glutamine on the genomic instability induced by Cytarabine/Ara-C in BALB/c mice
- The Promotion of Genomic Instability in Human Fibroblasts by Adenovirus 12 Early Region 1B 55K Protein in the Absence of Viral Infection
- Importance of analyzing the genomic instability in stem cell-based therapies
- Mechanistic insights of radiation-induced endothelial senescence impelling glioblastoma genomic instability at relapse
- Genomic Instability in cancer I: DNA-Repair triggering primitive hereditary 4n-Skewed, amitotic division-system, the culprit in EMT/MET/Metaplasia cancer …
- RNA processing: a new player of genomic instability in multiple myeloma
- Wwox Deletion in Mouse B Cells Leads to Genomic Instability, Neoplastic Transformation, and Monoclonal Gammopathies
- Aberrant DNA Polymerase Beta Enhances H. pylori Infection Induced Genomic Instability and Gastric Carcinogenesis in Mice
- … virus type-1 tax oncoprotein dissociates NF-κB p65RelA-Stathmin complexes and causes catastrophic mitotic spindle damage and genomic instability
- Proteomic and Interactome Approaches Reveal PAK4, PHB-2, and 14-3-3η as Targets of Overactivated Cdc42 in Cellular Responses to Genomic Instability
- Effects of two organomodified clays intended to food contact materials on the genomic instability and gene expression of hepatoma cells
- Abstract PO010: The inhibition of IWS1 phosphorylation promotes genomic instability, the cGAS/STING pathway activation and PD-L1 levels, through the U2AF2 …
- The molecular crosstalk: oxidative stress, genomic instability and neurodegenerative disorders
- Genomic instability and mitochondrial homeostasis in cancer: does chromatin have a say?
- 1p36 is a chromosomal site of genomic instability in cervical intraepithelial neoplasia
- CTC phenotype classifier to identify mCRPC patients (pts) with high genomic instability CTCs and to predict failure of androgen ecreptor signaling (AR Tx) and taxane …
- Early hereditary diffuse gastric cancer (eHDGC) is characterized by subtle genomic instability and active DNA damage response
- Genomic instability: The pivotal role of mutant p53 in human cancers
- Genomic instability in kidney cancer: etiologies and treatment opportunities
- Genomic instability and cancer metastasis
- Genomic instability of TnSMU2 contributes to Streptococcus mutans biofilm development and competence in a cidB mutant
- MiRome architecture and genomic instability
- The role of telomere dysfunction in genomic instability and age-related diseases
- Protracted p53-independent stimulation of p21WAF1/Cip1 fuels genomic instability by deregulating the replication licensing machinery
- Assessment of induced genomic instability in rat primary astrocytes exposed to intermediate frequency magnetic fields
- Radiation and chemical induced genomic instability as a driver for environmental evolution
- Binding of FANCD2 to SRSF1 Splicing Factor Prevents Genomic Instability through R Loop Regulation
- TCDD-induced mitochondrial superoxide production does not lead to mitochondrial degeneration or genomic instability in human SH-SY5Y neuroblastoma cells
- Electromagnetic Fields, Genomic Instability and Cancer: A Systems Biological View
- Epigenetic error and large-scale genomic instability in cancer
- Nuclear polymorphism induced genomic instability in cluster bean [Cyamopsis tetragonoloba (L.) Taub.](Fabaceae)
- Impact of Topoisomerases Complex Deregulation on Head and Neck Carcinoma Genomic Instability
- Author Correction: hnRNP H/F drive RNA G-quadruplex-mediated translation linked to genomic instability and therapy resistance in glioblastoma
- Traditional Indian sports–A case-control study on Kho Kho players investigating genomic instability and oxidative stress as a function of metabolic genotypes
- Female-biased embryonic death from genomic instability-induced inflammation
- Genomic Instability during Early Differentiation of Embryonic Stem Cells
- Stathmin/Op18 depletion induces genomic instability and leads to premature senescence in human normal fibroblasts
- Genomic instability and circulating tumor cells in prostate cancer
- Mitotic systemic genomic instability in yeast
- Genomic instability and genetic heterogeneity in neuroblastoma
- Association between Glycated Hemoglobin A1c Levels with Genomic Instability in Type 2 Diabetes Mellitus Patients.
- Flap endonuclease 1 mutations A159V and E160D cause genomic instability by slowing reaction on double-flap substrates
- Association between genomic instability and evolutionary chromosomal rearrangements in Neotropical Primates
- Perspectives on the role of bystander effect and genomic instability on therapy-induced secondary malignancy
- Suppression of genomic instability by replicative senescence and crisis
- Genomic instability and DNA damage repair in clear cell renal cell carcinoma.
- Genomic instability is an early event driving chromatin reorganization and escape from oncogene-induced senescence
- Distinct genomic instability landscape of lung adenocarcinoma associated with treatment and metastasis.
- Genomic instability in Larynx cancer
- … (PTC) harboring the AGK-BRAF and RET/PTC3 fusion in a mutually exclusive pattern reveals distinct levels of genomic instability and nuclear organization …
- Disabling the Fanconi Anemia Pathway in Stem Cells Leads to Radioresistance and Genomic Instability
- Author Correction: ZSCAN10 expression corrects the genomic instability of iPSCs from aged donors
- Investigation of the Genes sll1354, sll1165, and sll1520 in Genomic Instability in Cyanobacterium Synechocystis sp. PCC 6803
- Genomic instability in peripheral blood lymphocytes of patients diagnosed with high-grade squamous intraepithelial lesions: CIN 2 versus CIN 3
- Geminiviral βC1 orchestrates organellar genomic instability to augment viral infection by hijacking host RecA
- 1141P Prediction of cancer genomic instability using MALDI-imaging
- Genomic Instability and the Oncohistone H3K27M Drive Gliomagenesis in a Murine Model
- Genomic Instability and TP53 Genomic Alterations Associate With Poor Antiproliferative Response and Intrinsic Resistance to Aromatase Inhibitor Treatment
- RAD51 inhibitor reverses etoposide-induced genomic toxicity and instability in esophageal adenocarcinoma cells
- Polyphenol rich fruit attenuates genomic instability, modulates inflammation and cell cycle progression of offspring from fatty acid intake maternal
- G-quadruplex DNA drives genomic instability and represents a targetable molecular abnormality in ATRX-deficient malignant glioma
- Establishment of HindIIIG-1 Cell Line, Obtained after Irradiation of HindIIIG Cells Resistant to Apoptosis, Characterizes by Genomic Instability, Altered DNA Repair …
- An investigation of genomic instability and its impact on cancer development and heterogeneity
- Identification of candidate regulators of genomic instability in human lung adenocarcinoma through a new cross-species in silico analysis
- Developmental disabilities, autism, and schizophrenia at a single locus: complex gene regulation and genomic instability of 15q11-q13 cause a range of …
- Genomic Instability and Invasion in Breast Cancer
- … p53 predisposes head and neck keratinocytes and squamous cell carcinoma cells to replicative stress and genomic instability through minichromosome maintenance …
- Pan-cancer analysis of clonal evolution reveals the costs and adaptive benefits of genomic instability
- A genomic instability-based model for Barrett’s oesophagus progression
- p53-TIGAR axis-mediated glycolytic suppression attenuates DNA damage and genomic instability in Fanconi anemia hematopoietic stem cells
- Understanding How Genetic Mutations Collaborate with Genomic Instability in Cancer. Cells 2021, 10, 342
- … defence mechanisms. Potential implications of IFN-alfa induced changes in TP53, NRF2 and CXCR4 for genomic instability and CD34+ mobilisation
- 79 Extensively validated HLA LOH algorithm demonstrates an association between HLA LOH and genomic instability
- Identification of Genomic Instability Related Lncrna Signature Associated with Immune Microenvironment in Pancreatic Cancer
- 814 SMAD4 AS A POTENTIAL GATEKEEPER FOR GENOMIC INSTABILITY AND MTOR-MEDIATED TUMORIGENESIS IN ESOPHAGEAL ADENOCARCINOMA
- Combining methylation markers, genomic instability, and next generation sequencing as a panel for endometrial cancer detection via intravaginal tampon collection
- Group benefits from genomic instability
- Molecular cytogenetic characterization of HPV types 16 and 18 cervical cancers: Acquired genomic instability by E6 and E7 oncoproteins
- Loss of TRIM33 in Multiple Myeloma correlates with increased genomic instability
- Children’s, Adult’s and Family’s Emotional Stress in Context of Genomic Instability
- Cell rounding causes genomic instability by dissociation of single-stranded DNA-binding proteins
- Charting the landscape of genomic instability in acute myeloid leukemia: Interaction between G-quadruplexes and heme oxygenase-1 in leukemia
- Study of telomere dysfunction in TP53 mutant LoVo cell lines as a model for genomic instability
- How would preclinical Alzheimer’s disease (AD pathology) occur? An insight from a genomic instability mouse model
- Bone Marrow Microenvironment Induces Genomic Instability and Enables Clonal Evolution in Multiple Myeloma
- P4570 Reproductive health risks and y chromosome genomic instability in male staff working in cardiac catheterization laboratory with chronic low-dose x-ray …
- Genomic instability in an interspecific hybrid of the genus Saccharomyces: a matter of adaptability
- … of physico-chemical parameters of non-contact (electrochemical) activated drinking water is associated with induction of genomic instability of cultivated human blood …
- Genomic Instability Induced by High Energy Charged Particles
- Dysregulated Aid/Apobec family proteins promote genomic instability in multiple myeloma
- Despite of DNA repair ability the Fanconi anemia mutant protein FANCGR22P destabilizes mitochondria and leads to genomic instability via FANCJ helicase
- Immune Microenvironment Contributes to Dysregulation of Aid/Apobec Expression and Genomic Instability in Multiple Myeloma
- … an in vitro fluidics approach to model the evolution of metastatic breast cancer reveals shear stress as a possible driver of genomic instability and somatic mutation
- FOXM1 Expression and Contribution to Genomic Instability and Chemoresistance in High-Grade Serous Ovarian Cancer
- Genomic Instability Profiles at the Single Cell Level in Mouse Colorectal Cancers of Defined Genotypes. Cancers 2021, 13, 1267
- Genomic instability associated with formation of RNA: DNA hybrids and molecular mechanisms of its suppression
- IL-17-Mediated Inflammation Promotes Cigarette Smoke-Induced Genomic Instability
- Temporal Dynamics of Genomic Alterations in a BRCA1 Germline–Mutated Pancreatic Cancer With Low Genomic Instability Burden but Exceptional …
- Transgenerational genomic instability in the first generation offspring of mice exposed to low-intensity red and near-infrared irradiation in vivo
- Group benefits from genomic instability: A tale of antibiotic warriors in Streptomyces
- Abstract P4-01-03: Computer vision and machine learning allows for the prediction of genomic instability using circulating tumor cell morphology in triple negative …
- The Impact of Genomic Instability on Germline Development and Mutation Accumulation in Mice
- Genomic instability and its detection technologies for clinical application in cancer patients
- Genomic Instability and Shared Mechanisms for Gene Diversification in Two Distant Immune Gene Families: The Plant NBS-LRR Genes and the
- Tumor Evolution and Therapeutic Choice Seen through a Prism of Circulating Tumor Cell Genomic Instability. Cells 2021, 10, 337
- DNA Repair, Genomic Instability and Cancer
- Telomere-related genomic instability in papillary thyroid cancers: a preliminary study
- Long noncoding RNAs generated from the BRCA1 pseudogene regulate genomic instability and homologous recombination repair
- EXTH-34. G-QUADRUPLEX DNA DRIVES GENOMIC INSTABILITY AND REPRESENTS A TARGETABLE MOLECULAR ABNORMALITY IN ATRX-DEFICIENT …
- Mechanical Regulation of Autophagy, Chemoresistance and Genomic Instability in Breast Cancer
- P-057: A helicase “ASCC3” is coupled to FEN1-mediated genomic instability and cancer cell proliferation
- TDP1 deficiency and genomic instability in non-replicating cells
- Genomic instability of lymphocytes in patients with lung cancer with combined ischemic heart disease
- Inhibition of Kynurenine Signaling Decreases Glioblastoma Multiforme Genomic Instability and Sensitizes Cells to Chemotherapeutic Treatment
- Occupational exposure to pesticides in tobacco fields: the integrated evaluation of nutritional intake and susceptibility on genomic and epigenetic instability
- Characterizing the role of POLQ variants in genomic instability and cancer
- Mitigation of Iron Irradiation-Induced Genotoxicity and Genomic Instability by Postexposure Dietary Restriction in Mice
- EPCO-36. GENOMIC INSTABILITY AND TRANSCRIPTOMIC SIGNATURES UNDERLYING EPIGENETIC MENINGIOMA SUBGROUPS REVEALS MECHANISMS OF …
- Differential Genomic Instability-Associated LncRNAs Predict Differences of Clinical Outcome and Immunity in Left-And Right-Sided Colon Adenocarcinoma
- P08. 18 Replication stress as a driver of genomic instability in malignant gliomas
- APOBEC3B promotes genomic instability in myeloma cells
- Genomic Instability: DNA Repair and Cancer
- New connection between transcriptional regulation and genomic instability
- A role for ARHGAP35 in regulating genomic instability in NSCLC
- Comparative genomic analysis of Mycobacterium tuberculosis reveals evolution and genomic instability within Uganda I sub-lineage
- ABL1 Kinase Plays an Important Role in Spontaneous and Melphalan-Induced Genomic Instability in Multiple Myeloma: Potential Therapeutic Application
- Genomic instability as a link between cancer and aging
- CML-182: SETD2 Loss of Function Induces Genomic Instability in CML and May Contribute to Disease Progression to Blast Crisis
- Catalytically inactive Cas9 impairs DNA replication fork progression to induce focal genomic instability
- Letter to Editor Re: Fang et al entitled “Assessment of Genomic Instability in Medical Workers Exposed to Chronic Low-Dose X-Rays in Northern China”
- Genomic Instability at Single Cell Resolution
- Topoisomerase 1 dependent R-loop deficiency as a mechanism underlying oncogene-induced replication stress and genomic instability
- Lysosomal degradation ensures accurate chromosomal segregation to prevent genomic instability
- Loss of nuclear envelope phosphatase CTDNEP1 drives aggressive medulloblastoma by triggering MYC amplification and genomic instability
- Checkpoint defects require WRNIP1 to counteract R-loop-associated genomic instability
- Mechanical Regulation of Genomic Instability in Cancer
- Understanding genomic instability induced by telomere shortering
- A special issue on the DNA damage response and genomic instability
- Nuclear Envelope Rupture And Genomic Instability In Cancer
- Base Excision Repair and Homologous Recombination Pathway Intermediates Drive Genomic Instability and Evolution in Myeloma
- Fusion of immortalized myoblasts induces genomic instability that drives tumour development and progression
- Investigating genomic instability features in hereditary cancers
- Spontaneous and induced chromosomal aberrations in peripheral blood of women with endometriosis: evidence of genomic instability.
- CHROMOSOMAL ASSOCIATIONS AND GENOMIC INSTABILITY IN IDIOPATHIC RECURRENT PREGNANCY LOSS (RPL), A PILOT SCALE STUDY
- Evolution of genomic instability in metastatic cancer.
- Spontaneous and induced chromosomal aberrations in peripheral blood of women with endometriosis: evidence of genomic instability
- Metabolic Regulation of DNA Repair–Mechanistic Links between Hyperglycemia and Genomic Instability
- FGF2 causes genomic instability
- Studies on genomic instability induced by radiation and chemicals
- Individual features of radiation-induced genomic instability in patients with glioblastoma
- EVALUATING THE LEVELS OF GENOMIC INSTABILITY IN ORAL CAVITY INJURIES: EXPRESSION OF SMYD2, SMYD3, AND EZH2 GENES
- Microsatellite instability (MSI) and homologous recombination deficiency (HRD) are mutually exclusive mechanisms of genomic instability
- Exploiting genomic instability as an Achilles’ heel in cancer
- Children’s Genomic Instability in Association with Balance of the Autonomous Nerve System Departments
- Investigation of genomic instability in cholesteatoma of patients
- Effects of genomic instability in populations of Drosophilae melanogaster from regions of Ukraine with different radiation impact factors
- Genomic instability in type 2 diabetes mellitus patients from Yucatan, Mexico
- Low ribosomal RNA genes copy number provoke genomic instability and chromosomal segment duplication events that modify global gene expression and plant …
- Correlative and functional analysis of genomic instability and immune response in colorectal and endometrial cancer
- Early on-treatment genomic instability level in cell free DNA as a predictive and prognostic marker in metastatic breast cancer patients
- Genomic instability in Hodgkin lymphoma: the past, the present and future
- A dual role of genomic instability on radiosensitivity in cancer cells
- Abstract A39: Molecular characterization of ETMRs reveals role for R-loop mediated genomic instability and new treatment options
- Role of PMNs in inhibition of DNA repair and induction of genomic instability
- Cancer‐associated variants of POLQ induce genomic instability
- Regulation of V (D) J Recombination: Mechanisms that Govern Locus Accessibility and Mitigate Against Genomic Instability
- Genomic instability associated to cell cycle deregulation
- DNA Replication Termination and Genomic Instability
- Exploiting genomic instability in Acute Myeloid Leukemia: when TP53 fails.
- Evaluation of genomic instability using microsatellite instability, ploidy status, and p53 expression in archival paraffin embedded tissue from primary ovarian cancer …
- The Role of the RNA-binding Protein ZFP36L1 in Suppression of Replication Stress-induced Genomic Instability
- Variants of Mre11 induce genomic instability
- Erratum: Cuceu, C., et al. Independent Mechanisms Lead to Genomic Instability in Hodgkin Lymphoma: Microsatellite or Chromosomal Instability. Cancers 2018, 10 …
- Comprehensive genomic instability characteristics analysis in Chinese patients with osteosarcoma
- Whole genome sequencing of ovarian granulosa cell tumours show heterogeneity, genomic instability and tumour evolution
- Recombine and Associate to Prevent Genomic Instability and Premature Aging
- Genomic instability and early-onset colorectal cancer: a new form of classifying the disease?
- Comparison of genomic instability (GI) scores for predicting PARP activity in ovarian cancer
- Genomic Instability in Colorectal Adenomas with and without Recurrence
- Genomic scar score: a robust model to predict recombination repair deficient based on genomic instability
- Proliferation during epithelial-to-mesenchymal transition induces genomic instability
- Disrupted Control of Origin Activation Promotes Genomic Instability Upon Loss of the Pole4 and Trp53 Tumour Suppressors
- PIGN gene expression aberration is associated with genomic instability and leukemic progression in acute myeloid leukemia with myelodysplastic features
- Confined Cancer Cell Migration and Its Impact on DNA Damage and Genomic Instability
- ABL kinase inhibitor increases cytotoxicity of chemotherapeutic agents while reducing/inhibiting genomic instability in multiple myeloma
- Unraveling the Interplay of XRN2 and PARP1 in Suppressing R-Loop-Generated Genomic Instability
- The genomic instability in clean-up workers of Chornobyl NPP with COPD
- Targeting genomic instability using a genomic and proteomic approach to identify molecular drivers of poor prognosis in cancer
- Understanding the Mechanisms Driving Genomic Instability in Adult T-Cell Leukemia/Lymphoma
- Antioxidant Enzyme Levels as Surrogate Markers for Genomic Instability in Leukemia Patients
- Prediction of genomic instability in triple-negative breast cancer patients utilizing a CTC phenotype classifier
- Abstract PO-032: Mechanistic studies of hypoxia as a driver of genomic instability in prostate cancer
- The role of pttg and pbf in genomic instability and DNA repair in thyroid cancer
- Molecular causes and mechanisms of genomic instability in G1-deregulated cell cycle
- Local Endothelial and Smooth Muscle Genomic Instability Reproduce Specific Features of Cardiovascular Aging
- From DNA Damage to Mutations: A Thorough Characterization of Somatic Genomic Instability in the Human Body
- Mutational profile and genomic instability according to response to therapy in rectal carcinomas
- The use of whole genome copy number variation (CNV) to measure genomic instability in mCRPC CTCs.
- Analysis of the Relationship between Genomic Instability, Heterozygosity Levels and Phenotype in Saccharomyces cerevisiae
- Mechanisms That Promote Adhesion Defects and Genomic Instability to Produce Invasive Prostate Cancer
- Smoke-Induced Genomic Instability in the Airway Epithelium: Role of IL-17-Mediated Inflammation
- Genomic instability is associated with increased immune infiltration and PDL1 expression in epithelial ovarian cancer
- Loss of NKX6. 3 During Gastric Carcinogenesis Enhances Genomic Instability and Promote Tumor Development
- Genomic Instability Features Predict the Chemotherapy Response and Distinct Immune Landscape in Gastric Cancer-A lncRNA-and UBQLN4-based Study
- Impact of Weight Loss Strategies and Dietary Antioxidants on Obesity Induced Genomic Instability
- A human bronchial epithelial cell model demonstrates a role for glutamine regulation in genomic instability and oncogenic transformation
- Genomic instability and genetic heterogeneity in neuroblastoma tumours
- Deletion of putative xenobiotic response elements (XREs) in hpol κ alters the replication stress response and overall genomic instability in glioblastoma cells
- MicroRNA-20a-mediated loss of autophagy contributes to breast tumorigenesis by promoting genomic damage and instability
- Dicamba causes genomic instability in Phaseolus vulgaris seedlings
- Genomic instability changes of circulating tumor DNA reflect the responses to chemotherapy or targeted therapy in advanced gastric cancer
- Abstract PO-001: xCT expression alters the epigenome and induces genomic instability
- Abstract P2-04-01: Cyclin dependent kinase 7 (CDK7) inhibition promotes genomic instability and mitotic catastrophe in triple negative breast cancer
- Gnal haploinsufficiency causes genomic instability and increased sensitivity to haloperidol
- Genomic instability reflected by elevated Alu retroelement copy-number among workers exposed to diesel engine exhaust
- Re: Choices have consequences: the nexus between DNA repair pathways and genomic instability in cancer
- Genomic Instability in Severe Congenital Neutropenia, a Leukemia Predisposition Syndrome
- ABL Tyrosine Kinase Plays an Important Role in Mechanisms Involved in Genomic Instability in Multiple Myeloma
- EXTH-03. COMBINED TOP1 AND PARP INHIBITION ENFORCES GENOMIC INSTABILITY AND CELL DEATH IN PTEN-DEFICIENT GLIOBLASTOMA
- Genetically Engineering a Viral Sensor to Identify Environmental and Genetic Factors that Converge to Elicit Neuronal Genomic Instability in Parkinsonism
- Understanding genetic and epigenetic mechanisms of genomic instability, phenotypic diversity and resistance in cancer
- Role of PKCepsilon in cell division and differentiation: implication for genomic instability and autoimmunity
- RPA exhaustion as a major cause of genomic instability in polymerase eta-deficient cells
- A New Paradigm for Radiation-Induced Persistent Cellular Stress and Genomic Instability in Lung Carcinogenesis
- A Neil1 DNA glycosylase germline variant induces genomic instability and cellular transformation
- Targeting Homologous Recombination Increases Cytotoxicity While Reducing Genomic Instability Induced By Melphalan in Myeloma
- UNDERSTANDING THE MECHANISM OF GENOMIC INSTABILITY DURING REPLICATIVE AGING IN BUDDING YEAST
- Programmed Genomic Instability Regulates Neural Transdifferentiation of Human Microvascular Pericytes
- Alterations in peroxisomal function induced by genomic instability and their relevance for aging
- Characterization of Acetaldehyde-Induced Genomic Instability During DNA Replication in Esophageal Keratinocytes
- Abstract B58: Modeling oncogenic events in breast cancer precursor cells to study cancer evolution and genomic instability
- Contributions of Proofreading Deficiencies in DNA Polymerase ε to Genomic Instability
- Role of SFPQ function in RNA: DNA hybrids related genomic instability in telomeres
- Spaceflight mutagenesis of purple-leaf rice was the manifestation of genomic instability induced by the activation of transposon mPing
- Methods to Monitor DNA Repair Defects and Genomic Instability in the Context of a Disrupted Nuclear Lamina
- How germ line epigenetic regulators contribute to gene expression during genomic instability
- Genomic instability as a marker of poor prognosis in advanced prostate cancer: Subclonal insights from whole-genome sequencing of single circulating tumor cells
- A Study of Genomic Instability in Chronic Lymphocytic Leukaemia (CLL)
- Influence of aerosols of the Aral Sea on reproductive function and genomic instability
- Targeting genomic instability in embryonal tumors with multilayered rosettes (ETMR)
- Elucidating novel pathways of genomic instability in cutaneous T-cell lymphomas Matthew Tsang, MS, University of Ottawa; Jennifer Gantchev, MS, McGill University; …
- Integrated exome-and single cell RNA-sequencing reveals a clone’s genomic instability and multifaceted fitness
- Assessment of genomic instability in Chinese Hamster ovary (CHO) cells
- Abstract B37: PARP inhibitor olaparib induces genomic instability in normal mammalian cells
- Abstract LB-289: Genomic instability and the development of high-grade gliomas
- Abstract IA06: Molecular mechanisms of lung cancer development: Between metabolic reprogramming and genomic instability in the field of cancerization
- SMAD4 as a potential gatekeeper for genomic instability and mTOR-mediated tumorigenesis in esophageal adenocarcinoma
- The role of retrotransposition and exosomal DNA in radiation-induced genomic instability
- Physiological And Exogenous Means of Regulating DNA Damage Response: Insights into Mechanisms of DNA Repair And Genomic Instability
- Neutrophil‐induced genomic instability impedes resolution of inflammation and wound healing
- TREX1-induced chromosome fragmentation at the interface of innate immunity and genomic instability
- Chromosomal radiosensitivity and genomic instability of Fanconi anaemia patients in South Africa
- MALDI-imaging: Identification of protein signatures of genomic instability in colorectal cancers
- A More Mature Immunophenotypic Make-up of Multiple Myeloma Clone (s) at Diagnosis Correlates With a Higher Genomic Instability
- Binding of FANCD2 to SRSF1 splicing factor prevents genomic instability through R-loop regulation
- Dietary riboflavin deficiency induces genomic instability of esophageal squamous cells that is associated with gut microbiota dysbiosis in rats [Erratum: Dec. 17, 2020 …
- … Tumors of the Uterus and Ovaries With Mullerian and Germ Cell or Trophoblastic Components Have a Somatic Origin and Are Characterized by Genomic Instability
- Abstract B27: The use of mouse models for understanding the in vivo impact of cancer-relevant genetic defects on genomic instability induced by human LINE-1 …
- O35. Chromosomal radiosensitivity and genomic instability of Fanconi Anaemia patients in South Africa
- Telomeres and Genomic Instability from Precancerous Lesions to Advanced Cancer–Understanding Through Ovarian Cancer
- Abstract LB-236: Increasing global DNA hypomethylation and genomic instability in colorectal cancer development
- Imaging features of genomic instability in circulating tumor cells (CTCs) from metastatic triple-negative breast cancer (metTNBC) patients (pts) who received PIKTOR.
- Genomic instability in BRCA1-deficient cells is a result of the anti-recombinogenic activity of BLM helicase
- Expression of endothelial progenitor cells and vascular endothelial growth factor according to genomic instability in colorectal liver metastases
- Deciphering the role of the protein phosphatase EYA4 in preventing genomic instability and breast cancer development
- Genomic Instability and Gene Dosage Obscures Clues to Virulence Mechanisms of F. tularensis species
- Genomic Instability and Aneuploidy of Hepatocellular Carcinomas (HCC) in Patients with Metabolic Risk Factors
- Role of Shelterin Complex and Alternative Telomere Lengthening in Genomic Instability and Disease Progression in Chronic Myeloid Leukemia
- Abstract SY37-01: Genomic instability and hypoxia as co-drivers of prostate cancer aggression
- Characterization of BRCA1-induced genomic instability and identification of a novel PARP1 interactor
- miR-181a is a key driver of genomic instability and ovarian cancer tumorigenesis through the regulation of RB1
- Transient Nuclear Envelope Rupture during Cell Migration: A Cause of Genomic Instability and a Novel Opportunity for Therapeutic Intervention
- Genomic instability changes acquired by HPV16 E6/E7 targeting multipolar mitoses aneuploidy: Cellular sequelae
- Fifteen years’ experience treating cells with inorganic arsenic, a molecule able to induce genetic/genomic instability and epigenetic changes even after its removal
- Expression of Genes Associated with Telomere Homeostasis in TP53 Mutant LoVo Cell Lines as a Model for Genomic Instability
- Multiple mechanisms can lead to genomic instability in Hodgkin lymphoma cell lines: Microsatellite or chromoso-mal instability related to telomere end fusion or …
- The role of genomic instability and expression of the p53 protein gene network in the processes of oncogenesis in first-and second-generation children living …
- Genomic Instability and a Preferential Involvement of Ras Pathway in the Myelodysplastic Syndromes Evolution to Secondary Acute Myeloid Leukemia
- The scent of genome complexity: exploring genomic instability in mouse Olfactory Epithelium
- Induction of bystander effects and genomic instability in mammalian cells exposed to X-radiation and 241Am alpha particle radiation
- HDAC3 overexpression is an independent predictor of poor prognosis and is associated with genomic instability in prostate cancer.
- ATRX Protects Cells Against Replication-Induced Genomic Instability
- … : Hypomethylation of Repetitive Elements in Precancerous Tissues Precedes Targeted Chromosome Instability in Primary Tumors and Widespread Genomic Instability …
- TransposablE ElEmEnTs occur morE frEquEnTly In auTIsm-rIsk gEnEs: ImplIcaTIons for ThE rolE of gEnomIc InsTabIlITy In auTIsm
- Signatures of genomic instability and DNA repair defects as determinants for tumour clonal dynamics and sensitivity to G-quadruplex stabilizers
- YM155 and BIRC5 downregulation induce genomic instability via autophagy-mediated ROS production and inhibition in DNA repair
- Correction to: miR-18a reactivates the Epstein-Barr virus through defective DNA damage response and promotes genomic instability in EBV-associated lymphomas
- Retrotransposon activation and genomic instability participate to Huntington Disease pathogenesis in a Drosophila melanogaster model
- Break-induced replication repair pathway promotes mutagenesis and genomic instability in Saccharomyces cerevisiae
- Investigating Nucleotide Deficiency-Based Genomic Instability and CRISPR/Cas9-mediated Genomic Addition for the Therapeutic Applications of Human …
- SMC5 CONDITIONAL DEPLETION IN MURINE CEREBRAL CORTEX LEADS TO MICROCEPHALY AND GENOMIC INSTABILITY
- Functional characterization of the nuclear prolyl isomerase FKBP25: A multifunctional suppressor of genomic instability
- S895 POT1 MUTATIONS DRIVE GENOMIC INSTABILITY AND CONFER SYNTHETIC LETHALITY WITH G-QUADRUPLEX STABILIZING AGENTS IN CHRONIC …
- Abstract P4-07-06: Cyclin dependent kinase 7 (CDK7) inhibition with THZ1 induces mitotic failure and increases genomic instability in triple negative breast cancer
- Genomic instability (GI) score post-neoadjuvant chemotherapy (NACT) to predict overall survival (OS) in high grade ovarian cancer (HGSOC).
- Aberrant Activation of the Kynurenine Pathway in Gliomas Increases Polymerase Kappa Expression and Promotes Genomic Instability and Chemoresistance
- Abstract ES6-3: Systems approaches to attacking cancer vulnerabilities defined by metabolic, de-differentiation and genomic instability states
- Thymocyte selection-associated HMG box protein (TOX) induces genomic instability in T-cell acute lymphoblastic leukemia
- The E2F1 corepressor BIN1 is a novel tumor suppressor RB1-binding cofactor for cell-cycle arrest and genomic instability
- Abstract PD5-05: Genomic instability and poor antiproliferative response to aromatase inhibitor treatment: A POETIC study
- A balance of genomic instability, tumor-immune contexture and TGF-β signaling contributing to exclusion of T cells governs response to PD-L1 checkpoint blockade
- Po-212 CEP55 over-expression causes genomic instability to initiate spontaneous tumour formation in vivo
- Telomeres-Genome-wide identification of factors controlling the telomere damage response and telomere-driven genomic instability-ERC
- Abstract AP12: FOXM1 INDUCES DNA REPLICATION STRESS AND PROMOTES GENOMIC INSTABILITY DOWNSTREAM OF CYCLIN E1 IN HIGH-GRADE …
- … CHARACTERIZATION OF A NOVEL HUMAN CLIVAL CHORDOMA XENOGRAFT MODEL DEMONSTRATES INHERENT TUMOR GENOMIC INSTABILITY
- B30 MOLECULAR AND IMMUNOLOGICAL ASPECTS OF LUNG CANCER: Il-17-Mediated Inflammation Promotes Cigarette Smoke-Induced Genomic Instability
- … of melanin to dissociate the water molecule like chlorophyll in plants: Implications in the assessment and understanding of genomic instability and Warburg effect in …
- … in Base Composition Pattern but Diverse in Sequence—A Combination Ensuring Similar Function but Avoiding Repetitive‐Regions‐Related Genomic Instability
- CBMT-17. DEFECTIVE QKI-DEPENDENT LIPID METABOLISM INDUCES GENOMIC INSTABILITY AND SENSITIZES GLIOBLASTOMA TO IMMUNOTHERAPY
- A Symbiotic Microbe’s Life: Finding the Host with the Most Leads to Genomic Instability, Deletions
- CADD-27. G-QUADRUPLEX DNA DRIVES GENOMIC INSTABILITY AND REPRESENTS A TARGETABLE MOLECULAR ABNORMALITY IN ATRX-DEFICIENT …
- … Treatment with Pim Kinase Inhibitor Downregulates Alternative Non-Homologous End-Joining Repair and Decreases Genomic Instability in FLT3-ITD Cells …
- DNA Repair Deficiency, Genomic Instability and Immune Profiling in a Phase 1 Study of Locally Advanced Pancreatic Cancer Patients Treated with Veliparib …
- Phenotypic circulating tumor cell (CTC) classifier of genomic instability (GI) associates with improved overall survival (OS) for metastatic castration-resistant prostate …
- RDNA-16. THE ROLE OF RAD52 IN GENOMIC INSTABILITY AND THERAPEUTIC RESISTANCE OF MALIGNANT GLIOMAS
- PO-227 The effect of chronic mild hypoxia on genomic instability in HER2-overexpression breast cancer cell line SK-BR-3
- P12-Cell-cycle perturbation, atypical mitosis and micronuclei in Caco-2 cells as indicator of radiation-induced genomic instability
- Lack of Casein Kinase 1 Delta Promotes Genomic Instability-The Accumulation of DNA Damage and Down-Regulation of Checkpoint Kinase 1
- LSC-2017-IL-17-mediated inflammation promotes cigarette smoke-induced genomic instability
- The Role of 14-3-3 Gamma in Promoting Genomic Instability
- Vitamin D3 as adjuvant in the treatment of type 2 diabetes mellitus: modulation of genomic and biochemical instability
- Genomic inversions and GOLGA core duplicons underlie disease instability at the 15q25 locus
- … single cell-derived colorectal cancer cell lines is dominated by the continued selection of tumor-specific genomic imbalances, despite random chromosomal instability
- Genomic clustering of fitness‐affecting mutations favors the evolution of chromosomal instability
- Evaluation of oxidative DNA damage, genome instability and accelerated genomic ageing in childhood obesity
- Comprehensive genomic profiling of colorectal cancers with and without microsatellite instability (MSI) and elevated microsatellite alterations at selected …
- Insights into the genomic plasticity of Pseudomonas putida KF715, a strain with unique biphenyl‐utilizing activity and genome instability properties
- Recurring genomic structural variation leads to clonal instability and loss of productivity
- Analysis of genome instability using genomic and bioinformatic approaches
- Genomic landscape of copy number variation and copy neutral loss of heterozygosity events in equine sarcoids reveals increased instability of the sarcoid genome
- Fusion kinases identified by genomic analyses of sporadic microsatellite instability–high colorectal cancers
- Proteomic and genomic signatures of repeat instability in cancer and adjacent normal tissues
- Genomic and transcriptomic characterization of heterogeneous immune subgroups of microsatellite instability-high colorectal cancers
- Genomic and immunological features of microsatellite instability in colon cancer
- The genomic basis of mood instability: identification of 46 loci in 363,705 UK Biobank participants, genetic correlation with psychiatric disorders, and association with …
- Isolation by instability: Historical climate change shapes population structure and genomic divergence of treefrogs in the Neotropical Cerrado savanna
- Genomic Alterations of NTRK, POLE, ERBB2, and Microsatellite Instability Status in Chinese Patients with Colorectal Cancer
- Genomic Profiling for KRAS, NRAS, BRAF, Microsatellite Instability, and Mismatch Repair Deficiency Among Patients With Metastatic Colon Cancer
- Single cell multi-omics analysis of chromothriptic medulloblastoma highlights genomic and transcriptomic consequences of genome instability
- LaCl3 induces genomic DNA instability and increases DNA methylation levels in wheat roots
- Evaluation of microsatellite instability (MSI) status in 11,573 diverse solid tumors using comprehensive genomic profiling (CGP).
- Integrated analysis of genomic and epigenomic instability for CHO cell line engineering
- Evaluation of microsatellite instability (MSI) status in gastrointestinal (GI) tumor samples tested with comprehensive genomic profiling (CGP).
- Prevalence of microsatellite instability and association with pembrolizumab (P) usage in a real-world clinico-genomic database.
- Genomic profiling and mutation burden of Chinese prostate patients with microsatellite instability.
- Genomic alterations, mutation burden, and microsatellite instability status of Chinese intrahepatic cholangiocarcinoma
- Genomic signatures of past and present chromosomal instability in the evolution of Barrett’s esophagus to esophageal adenocarcinoma
- The genomic basis of mood instability: identification of 46 loci in 363,705 UK Biobank participants, genetic correlation with psychiatric disorders, and association with …
- … of ovarian cancer patients for immunotherapy by concurrent assessment of tumor mutation burden (TMB), microsatellite instability (MSI) status, and targetable genomic …
- Correction: The genomic basis of mood instability: identification of 46 loci in 363,705 UK Biobank participants, genetic correlation with psychiatric disorders, and …
- The clonal composition of colorectal cancer cell lines is defined by the maintenance of specific genomic imbalances, not by ongoing chromosomal instability
- Genomic and Immunologic Markers of Intrinsic Resistance to Pembrolizumab Monotherapy in Microsatellite Instability-High Gastric Cancer: Observations from …
- Correction: The genomic basis of mood instability: identification of 46 loci in 363,705 UK Biobank participants, genetic correlation with psychiatric disorders, and …
- 1479P Clinicopathological and genomic characteristics of DNA Mismatch Repair-Deficient (dMMR) and microsatellite instability-high (MSI-H) resected gastric …
- AB095. P069. Identification of therapeutic genomic alterations by investigating cancer-related genes and microsatellite instability: road to precision medicine for …
- Genomic insult oriented mitochondrial instability and proliferative hindrance in the bone marrow of aplastic mice including stem/progenitor population
- ARID1A genomic alterations driving microsatellite instability through somatic MLH1 methylation with response to immunotherapy in metastatic lung …
- Blood-based genomic profiling of cell-free DNA (cfDNA) to identify microsatellite instability (MSI-H), tumor mutational burden (TMB) and Wnt/B-Catenin pathway …
- … triage in endometrial adenocarcinoma (EA) by concurrent assessment of tumor mutation burden (TMB), microsatellite instability (MSI) status, and targetable genomic …
- Circulating tumor (ct) DNA-based comprehensive genomic profiling to identify microsatellite instability (MSI) and defective DNA damage repair (DDR) in prostate …
- P60. 07 Comprehensive Genomic Profiling of Microsatellite Instability-High Lung Cancer in China
- Abstract PS5-04: Therapeutic considerations in microsatellite instability high (MSI-H) breast cancers (BC) identified by comprehensive genomic profiling (CGP)
- … MMR) protein expression and somatic mutations (muts), microsatellite instability (MSI) and tumor mutational burden (TMB) in MSI-H and MMR-mutated tumor genomic …
- … (MMR) genes and associations with microsatellite instability (MSI), tumor mutational burden (TMB) and SM in other DNA repair pathways in 24,223 tumor genomic …
- Genomic instability, inflammatory signaling and response to cancer immunotherapy
- The molecular link between obesity and genomic instability in cancer development
- Processing DNA lesions during mitosis to prevent genomic instability
- Genomic instability in early systemic sclerosis
- Genomic instability drives tumorigenesis and metastasis and its implications for cancer therapy
- Apigenin in cancer therapy: Prevention of genomic instability and anticancer mechanisms
- Blocking genomic instability prevents acquired resistance to MAPK inhibitor therapy in melanoma
- USP1-trapping lesions as a source of DNA replication stress and genomic instability
- Comprehensive analyses identify RIPOR2 as a genomic instability-associated immune prognostic biomarker in cervical cancer
- Genomic Instability Evolutionary Footprints on Human Health: Driving Forces or Side Effects?
- Systems modelling predicts chronic inflammation and genomic instability prevent effective mitochondrial regulation during biological ageing
- Genomic Scar Score: A robust model predicting homologous recombination deficiency based on genomic instability
- Immune pathway upregulation and lower genomic instability distinguish EBV-positive nodal T/NK-cell lymphoma from ENKTL and PTCL-NOS
- The Role of DNA Repair in Genomic Instability of Multiple Myeloma
- Metabolic regulation by p53 prevents R-loop-associated genomic instability
- Loss of phosphatase CTDNEP1 potentiates aggressive medulloblastoma by triggering MYC amplification and genomic instability
- The Effect of Mammalian Sex Hormones on Polymorphism and Genomic Instability in the Common Bean (Phaseolus vulgaris L.)
- Molecular chaperones in DNA repair mechanisms: Role in genomic instability and proteostasis in cancer
- TYMS promotes genomic instability and tumor progression in Ink4a/Arf null background
- Genomic Instability and Protumoral Inflammation Are Associated with Primary Resistance to Anti–PD-1+ Antiangiogenesis in Malignant Pleural Mesothelioma
- Cytogenetics in fanconi anemia: The importance of follow-up and the search for new biomarkers of genomic instability
- Low-molecular-weight cyclin E deregulates DNA replication and damage repair to promote genomic instability in breast cancer
- Identification of LncRNA prognostic signature associated with genomic instability in pancreatic adenocarcinoma
- A genomic instability-related lncRNA model for predicting prognosis and immune checkpoint inhibitor efficacy in breast cancer
- Nasopharyngeal Carcinoma Progression: Accumulating Genomic Instability and Persistent Epstein–Barr Virus Infection
- The Role of Iron in DNA and Genomic Instability in Cancer, a Target for Iron Chelators That Can Induce ROS
- Genomic instability genes in lung and colon adenocarcinoma indicate organ specificity of transcriptomic impact on Copy Number Alterations
- APOBEC3 mutational signatures are associated with extensive and diverse genomic instability across multiple tumour types
- Theranostic Interpolation of Genomic Instability in Breast Cancer
- Obesity-related genomic instability and altered xenobiotic metabolism: possible consequences for cancer risk and chemotherapy
- LncRNAs-associated to genomic instability: A barrier to cancer therapy effectiveness
- The signature based on seven genomic instability-related genes could predict the prognosis of acute myeloid leukemia patients
- A novel genomic instability-derived lncRNA signature to predict prognosis and immune characteristics of pancreatic ductal adenocarcinoma
- Aberrant APOBEC3C expression induces characteristic genomic instability in pancreatic ductal adenocarcinoma
- Epstein–Barr virus is an agent of genomic instability
- Tumour break load is a biologically relevant feature of genomic instability with prognostic value in colorectal cancer
- R-loop-associated genomic instability and implication of WRN and WRNIP1
- Fanconi anemia and dyskeratosis congenita/telomere biology disorders: Two inherited bone marrow failure syndromes with genomic instability
- Mutagenic effects of sodium azide on in vitro mutagenesis, polymorphism and genomic instability in wheat (Triticum aestivum L.)
- Genomic instability is defined by specific tumor microenvironment in ovarian cancer: a subgroup analysis of AGO OVAR 12 trial
- Cancer metabolism challenges genomic instability and clonal evolution as therapeutic targets
- Global genomic instability caused by reduced expression of DNA polymerase ε in yeast
- Effects of mammalian sex hormones on regeneration capacity, retrotransposon polymorphism and genomic instability in wheat (Triticum aestivum L.)
- Heavy metal ions exchange driven protein phosphorylation cascade functions in genomic instability in spermatocytes and male infertility
- KMT2C-deficient tumors have elevated APOBEC mutagenesis and genomic instability in multiple cancers
- Identification of a genomic instability-related long noncoding RNA prognostic model in colorectal cancer based on bioinformatic analysis
- Characterization of a pathway of genomic instability induced by R-loops and its regulation by topoisomerases in E. coli
- Multi-omics analysis based on genomic instability for prognostic prediction in lower-grade glioma
- Standardization of Cell Culture Conditions and Routine Genomic Screening under a Quality Management System Leads to Reduced Genomic Instability in …
- … microenvironment and cancer therapy for head and neck squamous cell carcinoma through identification of a genomic instability-related lncRNA prognostic …
- Identification and validation of a novel genomic instability-associated long non-coding RNA prognostic signature in head and neck squamous cell carcinoma
- Genomic instability caused by Arp2/3 complex inactivation results in micronucleus biogenesis and cellular senescence
- Effects of Zinc, Copper and Iron Oxide Nanoparticles on Induced DNA Methylation, Genomic Instability and LTR Retrotransposon Polymorphism in Wheat (Triticum …
- Tcf-1 promotes genomic instability and T cell transformation in response to aberrant β-catenin activation
- Genomic instability in individuals with sex determination defects and germ cell cancer
- Begomoviral βC1 orchestrates organellar genomic instability to augment viral infection
- Chemical characterization of Brazilian savannah Byrsonima species (muricis) and their impact on genomic instability and chemopreventive effects
- A Genomic Instability–Associated Prognostic Signature for Glioblastoma Patients
- Cerebrospinal Fluid Cell-Free DNA-Based Detection of High Level of Genomic Instability Is Associated With Poor Prognosis in NSCLC Patients With …
- Somatic mutations in DCC are associated with genomic instability and favourable outcomes in melanoma patients treated with immune checkpoint inhibitors
- The pediatric leukemia oncoprotein NUP98-KDM5A induces genomic instability that may facilitate malignant transformation
- Metabolic clogging of mannose triggers dNTP loss and genomic instability in human cancer cells
- Modeling Global Genomic Instability in Chronic Myeloid Leukemia (CML) Using Patient-Derived Induced Pluripotent Stem Cells (iPSCs)
- Genomic instability evaluation by BMCyt and telomere length in Brazilian family farmers exposed to pesticides
- Can spike fragments of SARS-CoV-2 induce genomic instability and DNA damage in the guppy, Poecilia reticulate? An unexpected effect of the COVID-19 pandemic
- Evaluation of ethyl methanesulfonate-induced in vitro mutagenesis, polymorphism and genomic instability in wheat (Triticum aestivum L.)
- Chronic hypoxia is associated with transcriptomic reprogramming and increased genomic instability in cancer cells
- Identification of a Gene-Expression-Based Surrogate of Genomic Instability during Oral Carcinogenesis
- Genomic Instability in Somatic Hybridization between Poncirus and Citrus Species Aiming to Create New Rootstocks
- Cleavage-defective topoisomerase I mutants sharply increase G-quadruplex-associated genomic instability
- Genomic instability-related twelve-microRNA signatures for predicting the prognosis of gastric cancer
- Extract of Murraya koenigii selectively causes genomic instability by altering redox-status via targeting PI3K/AKT/Nrf2/caspase-3 signaling pathway in human non …
- Markers associated with genomic instability, immunogenicity and immune therapy responsiveness in Metaplastic carcinoma of the breast: Expression of …
- GIP: an open-source computational pipeline for mapping genomic instability from protists to cancer cells
- A somatic mutation-derived LncRNA signatures of genomic instability predicts the prognosis and tumor microenvironment immune characters in hepatocellular …
- Genomic instability as a major mechanism for acquired resistance to EGFR tyrosine kinase inhibitors in cancer
- Neutrophils and micronuclei: An emerging link between genomic instability and cancer-driven inflammation
- Development and validation of a genomic instability-related lncRNA prognostic model for hepatocellular carcinoma
- Ectopically Expressed Meiosis-Specific Cancer Testis Antigen HORMAD1 Promotes Genomic Instability in Squamous Cell Carcinomas
- Induction of ROS mediated genomic instability, apoptosis and G0/G1 cell cycle arrest by erbium oxide nanoparticles in human hepatic Hep-G2 cancer cells
- 210O Mutational signature analysis reveals patterns of genomic instability linked to resistance to endocrine therapy (ET)+/-CDK 4/6 inhibition (CDK4/6i) in estrogen …
- A Genomic Instability-Related Long Noncoding RNA Signature for Predicting Hepatocellular Carcinoma Prognosis
- The Influence of PARP, ATR, CHK1 Inhibitors on Premature Mitotic Entry and Genomic Instability in High-Grade Serous BRCAMUT and BRCAWT Ovarian …
- p53 reactivating small molecule PRIMA‑1MET/APR‑246 regulates genomic instability in MDA‑MB‑231 cells
- Human myeloid progenitor glucocorticoid receptor activation causes genomic instability, type 1 IFN‐response pathway activation and senescence in differentiated …
- Circumventing drug resistance through a CK2-targeted combination via attenuating endogenous AhR-TLS-promoted genomic instability in human colorectal cancer …
- p53-NEIL1 co-abnormalities induce genomic instability and promote synthetic lethality with Chk1 inhibition in multiple myeloma having concomitant 17p13 (del) and …
- Identification of genomic instability related lncRNA signature with prognostic value and its role in cancer immunotherapy in pancreatic cancer
- Prognostic Value of Genomic Instability of m6A-Related lncRNAs in Lung Adenocarcinoma
- Concordance between single-nucleotide polymorphism–based genomic instability assays and a next-generation sequencing–based homologous …
- Homologous Recombination Deficiency Score Determined by Genomic Instability in a Romanian Cohort
- Long non‑coding RNAs interact with RNA‑binding proteins to regulate genomic instability in cancer cells
- WiFi Related Radiofrequency Electromagnetic Fields Promote Transposable Element Dysregulation and Genomic Instability in Drosophila melanogaster
- Diagnostic and prognostic value of genomic instability-derived long non-coding RNA signature of endometrial cancer
- … instability-related prognostic risk score (MSI-pRS) defines a subset of lung squamous cell carcinoma (LUSC) patients with genomic instability and poor clinical …
- High Dietary Folic Acid Intake Is Associated with Genomic Instability in Peripheral Lymphocytes of Healthy Adults
- A Novel Subgroup of UCHL1-Related Cancers Is Associated with Genomic Instability and Sensitivity to DNA-Damaging Treatment
- Development of a genomic instability-derived lncRNAs-based risk signature as a predictor of prognosis for endometrial cancer
- Loss of CBX2 causes genomic instability and Wnt activation in high grade serous ovarian carcinoma cells
- Genomic Instability and Neurodegeneration
- Targeting IKKε in Androgen-Independent Prostate Cancer Causes Phenotypic Senescence and Genomic Instability
- Macrophage infiltration correlates with genomic instability in classic Hodgkin lymphoma
- Foreword Special Issue Genomic Instability in Tumor Evolution and Therapy Response
- Establishing a prognostic model based on three genomic instability-related LncRNAs for clear cell renal cell cancer
- Genomic instability and eye diseases
- Aflatoxin B1 Exacerbates Genomic Instability and Apoptosis in the BTBR Autism Mouse Model via Dysregulating DNA Repair Pathway
- Association of Genomic Instability Score, Tumor Mutational Burden, and Tumor-Infiltrating Lymphocytes as Biomarkers in Uterine Serous Carcinoma
- Cell-type-specific nuclear morphology predicts genomic instability and prognosis in multiple cancer types
- Telomere attrition and genomic instability in unexplained recurrent pregnancy loss in humans: A preliminary study
- Complete genome of the toxic mold Aspergillus pseudotamarii isolate NRRL 25517 reveals genomic instability of the aflatoxin biosynthesis cluster
- Macrophage Infiltration Correlates with Genomic Instability in Classic Hodgkin Lymphoma. Biomedicines 2022, 10, 579
- The mutation in splicing factor genes correlates with unfavorable prognosis, genomic instability, anti-tumor immunosuppression and increased …
- Genomic Instability in Cerebrospinal Fluid Cell-Free DNA Predicts Poor Prognosis in Solid Tumor Patients with Meningeal Metastasis
- Relationship of radiation-induced genomic instability and antioxidant production in the chamomile plant
- Modification Patterns of DNA Methylation-Related lncRNAs Regulating Genomic Instability for Improving the Clinical Outcomes and Tumour Microenvironment …
- Loss of p53 tumor suppression function drives invasion and genomic instability in models of murine pancreatic cancer
- The oncogenic fusion protein TAZ-CAMTA1 promotes genomic instability and senescence through hypertranscription
- Effects of genomic instability in populations of Drosophila melanogaster from regions of Ukraine with different impact of radiation factors
- Estrogen induces genomic instability in high-risk HPV-infected cervix and promotes the carcinogenesis of cervical adenocarcinoma
- Genomic instability in long-term culture of human adipose-derived mesenchymal stromal cells
- Artemisia vulgaris L., Artemisia alba Turra and their constituents reduce mitomycin C-induced genomic instability in human peripheral blood lymphocytes in vitro
- Genomic instability in patients with sex determination defects and germ cell cancer
- Incorporating RNA-based risk scores for genomic instability to predict breast cancer recurrence and immunogenicity in a diverse population
- Effects of Glycoalkaloids from Solanum lycocarpum on Genomic Instability
- Genomic instability and aging
- Oxidative Damage Induced Telomere Mediated Genomic Instability in Cells from Ataxia Telangiectasia Patients
- Use of liquid-based cytology samples reveals genomic instability and cell death in patients undergoing orthodontic treatment
- Bursts of genomic instability potentiate phenotypic and genomic diversification in Saccharomyces cerevisiae
- 2022-RA-935-ESGO Development of an academic genomic instability score for ovarian cancers
- WRNIP1 prevents transcription-associated genomic instability
- Construction of a novel LncRNA signature related to genomic instability to predict the prognosis and immune activity of patients with hepatocellular carcinoma
- Interaction Among Noncoding RNAs, DNA Damage Reactions, and Genomic Instability in the Hypoxic Tumor: Is it Therapeutically Exploitable Practice?
- Genomic instability, origin and evolution of cancer, and personalized immunotherapy
- Exosome-like vesicles released from ob/ob mouse adipose tissue enhance cell survival of cells with radiation-induced genomic instability
- SPRTN and TDP1/TDP2 Independently Suppress 5-Aza-2′-deoxycytidine-Induced Genomic Instability in Human TK6 Cell Line
- Genomic instability induced by radiation-mimicking chemicals is not associated with persistent mitochondrial degeneration
- Retraction: Genomic Instability in Liver Cells Caused by an LPS-Induced Bystander-Like Effect
- KMT2C deficiency promotes APOBEC mutagenesis and genomic instability in multiple cancers
- … radiation on large Japanese field mice in Fukushima reduced colony forming potential in hematopoietic progenitor cells without inducing genomic instability
- Over-Activation of Minichromosome Maintenance Protein 10 Promotes Genomic Instability in Early Stages of Breast Cancer
- Mutator-Derived lncRNA Landscape: A Novel Insight Into the Genomic Instability of Prostate Cancer
- Effects of curcumin and soy isoflavones on genomic instability of human colon cells NCM460 and SW620
- Identification of the prognostic signature based on genomic instability-related alternative splicing in colorectal cancer and its regulatory network
- Recombinant cell-detecting RaDR-GFP in mice reveals an association between genomic instability and radiation-induced-thymic lymphoma
- NF-κB-Induced R-Loops and Genomic Instability in HTLV-1-Infected and Adult T-Cell Leukemia Cells
- Chronic oxidative stress leads to genomic instability in the pathogenesis of fanconi anemia
- Development of genomic instability-associated long non-coding RNA signature: A prognostic risk model of clear cell renal cell carcinoma
- GCMS analysis of sadagura (smokeless tobacco), its enhanced genomic instability causing potential due to arsenic co-exposure, and vitamin-C supplementation as a …
- Genomic instability detected from the saliva of Head and Neck Squamous Cell Carcinoma patients: Association with clinical implications
- WRNIP1 PREVENTS G4/R-LOOP-ASSOCIATED GENOMIC INSTABILITY
- Combination of CDK12 inhibition and olaparib enhances genomic instability in cancer models
- TP53-dependent genomic instability
- The dark side of PLK1: Implications for cancer and genomic instability
- Topoisomerase 1-dependent R-loop deficiency drives accelerated replication and genomic instability
- Deciphering How Genomic Instability in Hematopoietic Cells Drives Tumorigenesis
- Demonstration That Loss of TET2 Impairs DNA Mismatch Repair Resulting in Clonally Restricted Genomic Instability
- TP53 Mutation Status Defines a Distinct Clinicopathological Entity of Therapy-Related Myeloid Neoplasm, Characterized By Genomic Instability and Extremely Poor …
- Genomic Instability Is a Mechanism for Diminished Male Fertility Following Chronic Dichlorvos Exposure
- PRAME induces genomic instability in uveal melanoma
- Expression of the cGAS-STING pathway is associated with high levels of genomic instability and immune cell infiltration in breast cancer
- Navigating the genomic instability mine field of osteosarcoma to better understand implications of non-coding RNAs
- Glucocorticoid receptor activation during human microglial differentiation leads to genomic instability and senescence
- ABL1 Kinase plays an important role in spontaneous and chemotherapy-induced genomic instability in multiple myeloma
- 119. Concordance of integrated analysis approaches to measure HRD genomic instability
- EP299/# 232 Genomic instability as a determinant of immune escape in ovarian cancer
- Genomic Instability in Carcinogenesis: The Role of Oxidative Stress
- Genomic instability and the link to infertility: A focus on microsatellites and genomic instability syndromes
- The Role of Meiomitosis and HORMAD1 in the Modulation of Genomic Instability and Transformation of Cutaneous Malignancies
- Long noncoding RNA signatures involved in the genomic instability of papillary thyroid carcinoma
- A genomic instability-associated lncRNA signature for predicting prognosis and biomarkers in lung adenocarcinoma
- Characterizing the role of DDX41 in opposing transcription-associated genomic instability
- Chromosomal instability as a source of genomic plasticity
- Mining high dimensional transcriptomic data to unravel the causes and consequences of genomic instability in cancers
- Analysis of the global gene expression profiles in genomic instability-induced cervical cancer cells
- Assessing patterns of genomic instability in recurrent osteosarcoma
- Can Spike Fragments of Sars-Cov-2 Induce Genomic Instability and DNA Damage in the Guppy, Poecilia Reticulate? An Additional Concern Study of Covid-19
- Metabolic clogging of mannose triggers genomic instability via dNTP loss in human cancer cells
- EP101/# 503 Relevance of genomic instability score, tumor mutational burden, and tumor infiltrating lymphocytes as biomarkers in uterine serous carcinoma
- Construction and validation of somatic mutation-derived LncRNA signatures of genomic instability to predict prognosis of hepatocellular carcinoma
- ATR-I774Yfs* 5 promotes genomic instability through micronuclei formation
- MEDB-42. GERMLINE ELP1 DEFICIENCY PROMOTES GENOMIC INSTABILITY AND SURVIVAL OF GRANULE NEURON PROGENITORS PRIMED FOR SHH …
- Dynamics of genomic instability of circulating tumor DNA in pancreatic cancer patients
- ATR-I774Yfs* 5 promotes genomic instability through micronuclei formation
- Flap Structure-Specific Endonuclease 1 Coordinates with a Helicase (ASCC3) to Drive Genomic Instability, Proliferation and Poor Clinical Outcome in Myeloma
- Analysis of BRCA2 Copy Number Loss and Genomic Instability in Circulating Tumor Cells from Patients with Metastatic Castration-resistant Prostate Cancer
- S152: SETD2/H3K36ME3 DEFICIENCY SUSTAINS GENOMIC INSTABILITY AND ENHANCES CLONOGENIC POTENTIAL OF CHRONIC MYELOID LEUKEMIA (CML …
- Defining the mechanisms contributing to genomic instability following RB loss
- Molecular Dysregulation Fuels Genomic Instability & Leukemogenesis
- Association of genomic instability of CDH1 gene with clinicopathological characteristics of gastric cancer
- Evaluation of the genotoxicity and genomic instability in patients with HBV, HCV and HCC using micronucleus and comet assay
- Gonadal Dysgenesis As A Marker Of Genomic Instability In Populations Of Drosophila Melanogaster From Different Of Radiation Factor Impact Regions Of Ukraine
- Elucidating genomic instability and its outcomes as cancer origin
- Mesothelioma Mouse Models with Mixed Genomic States of Chromosome and Microsatellite Instability
- Induction of ROS mediated genomic instability, apoptosis andG0/G1 cell cycle arrest by erbium oxide nanoparticles in human hepatic Hep‑G2 cancer cells
- Driver Gene Networks of Genomic Instability in Prostate Cancer Progression
- Exonuclease 1 Drives Growth and Genomic Instability in Multiple Myeloma through Interaction with CAD, a Key Protein Involved in De Novo Pyrimidine Biosynthesis
- … A057: Therapeutic efficacy of selective CDK7 inhibition in pancreatic cancer mediated by induction of R-loop formation, DNA replication stress and genomic instability
- A 4-lethal gene prognostic signature correlates with genomic instability and immunotherapy biomarker in stomach adenocarcinoma
- P02 ARGININE DEPRIVATION INDUCES ACQUISITION OF A SENESCENT PHENOTYPE AND FAVORS GENOMIC INSTABILITY IN MULTIPLE MYELOMA …
- Investigating the association between Lamin B1 and genomic instability in B cells
- Biomonitoring and predictive modelling of genomic instability in childhood obesity
- Comet assay as a bioindicator of genomic instability in hemodialysis diabetic patients
- Water Contamination by Delorazepam Induces Epigenetic Defects and Genomic Instability in the Embryos of the Clawed Frog Xenopus Laevis
- Newborn ribosomal DNA content as a potential early marker of genomic instability and longevity in association with prenatal air pollution exposure
- Genomic instability in blood cells from bovine with spontaneous tumours: an OneHealth perspective
- Genomic instability is enriched in localized prostate cancers from men of African ancestry.
- Determination of genomic instability caused by ionizing radiation in mammography
- Editor’s Note: Characterization of a Novel Mechanism of Genomic Instability Involving the SEI1/SET/NM23H1 Pathway in Esophageal Cancers
- The Adenylate-Uridylate-Rich element RNA binding protein ZFP36L1 suppresses replication stress-induced genomic instability
- Associations between genomic instability score (GIS), molecular characterization, and clinical outcomes in high grade serous ovarian cancers (HGSOC).
- Targeted protein degradation for disruption of key proteins that overcome genomic instability in cancers: Wee1 and KIFC1
- Integrative genomic analysis reveals hypermethylation triggered GPER1 loss is associated with genomic instability of endometrial cancer
- Targeting genomic instability in extrapulmonary small cell neuroendocrine cancers: A phase II study with ATR inhibitor berzosertib and topotecan.
- Dataset of Topoisomerase 1 dependent R-loop deficiency drives accelerated replication and genomic instability
- … PHOSPHATASE CTDNEP1 MUTATIONS POTENTIATE AGGRESSIVE MEDULLOBLASTOMA BY TRIGGERING MYC ACTIVATION AND GENOMIC INSTABILITY
- Correction to: Genomic instability induced by radiation-mimicking chemicals is not associated with persistent mitochondrial degeneration
- Tumor break load is a biologically relevant characteristic of genomic instability with prognostic value for patients with localized colorectal cancer
- Can Spike Fragments of Sars-Cov-2 Induce Genomic Instability and DNA Damage in the Guppy, Poecilia Reticulate? An Additional Concern Study of Covid-19
- Genomic Instability Involved During the Early Carcinogenesis of 4NQO-Induced Esophageal Squamous Cell Carcinoma in Mice
- Correction: The EZH2-PHACTR2-AS1-Ribosome Axis Induces Genomic Instability and Promotes Growth and Metastasis in Breast Cancer
- Exposure to butyrate metabolite mediates genomic instability in oropharyngeal keratinocytes
- The unusual duplication of a 69.9-kb long chromosomal segment produces two copies of an inverted repeat and generates genomic instability in a laboratory …
- Kub5‐Hera Deficiency Promotes R‐Loop‐Induced Genomic Instability and Carcinogenesis Following Whole‐Body Exposure to Ionizing Radiation
- Augmenting genomic instability in HPV head and neck cancer tumors through combination bromodomain and extra-terminal (BET) proteins inhibition and radiation …
- Abstract P5-13-09: Identifying homologous recombination deficiency in breast cancer: Genomic instability score thresholds differ in breast cancer subtypes
- Abstract P3-09-13: Androgen receptor loss is associated with genomic instability characterized by copy number alterations and mirna deregulation in triple-negative …
- Topoisomerase 1 suppresses replication stress and genomic instability by preventing interference between replication and transcription.
- Recurrent inversion polymorphisms in humans associate with genetic instability and genomic disorders
- Genomic landscape of microsatellite instability in Chinese tumors: a comparison of Chinese and TCGA cohorts
- Genomic and Immune Features in an Intrahepatic Cholangiocarcinoma Patient with Microsatellite Instability-High Suffered Rapid Acquired Resistance to PD-1 …
- Mechanisms of chromosomal instability (CIN) tolerance in aggressive tumors: surviving the genomic chaos
- Matched Paired Primary and Recurrent Meningiomas Points to Cell-Death Program Contributions to Genomic and Epigenomic Instability along Tumor Progression
- Ribodysgenesis: sudden genome instability in the yeast Saccharomyces cerevisiae arising from RNase H2 cleavage at genomic-embedded ribonucleotides
- Large-scale cancer genomic analysis reveals significant disparities between microsatellite instability and tumor mutational burden
- Genomic and Transcriptomic Analysis of Microsatellite Instability-High Colorectal Cancer Patients with Targetable Alterations Identifies Clinical Implications for …
- Genomic characterization and translational immunotherapy of microsatellite instability-high (MSI-H) in cholangiocarcinoma.
- Assessment of tumor mutation burden and microsatellite instability by single-cell circulating tumor cell genomic profiling
- Genomic landscapes to characterize mismatch-repair deficiency (dMMR)/microsatellite instability-high (MSI-H) gastrointestinal (GI) cancers stratified by tumor mutation …
- Comparative analysis of microsatellite instability-high (MSI-H) BRAF V600E-mutated versus MSI-H BRAF wild type colorectal cancers (CRC), including tumor …
- … mutation on immunologic characteristics of the tumor microenvironment (TME) and associated genomic alterations in patients with microsatellite instability-high (MSI-H …
