The biology of PGC-1α and its therapeutic potential PGC-1α: a key regulator of energy metabolism PGC-1α-mediated adaptations in skeletal muscle PGC-1α and PGC-1β regulate mitochondrial density in neurons Bioenergetic analysis of peroxisome proliferator-activated receptor γ coactivators 1α and 1β (PGC-1α and PGC-1β) in muscle cells Multiple environmental and genetic factors influence skeletal muscle PGC-1α and PGC-1β gene expression in twins … PGC-1α) coactivates the cardiac-enriched nuclear receptors estrogen-related receptor-α and-γ: identification of novel leucine-rich interaction motif within PGC … Role of PGC‐1α signaling in skeletal muscle health and disease Lipin 1 is an inducible amplifier of the hepatic PGC-1α/PPARα regulatory pathway PGC-1α: turbocharging mitochondria Impaired PGC-1α function in muscle in Huntington's disease PGC-1α, a new therapeutic target in Huntington's disease? PGC-1α in aging and anti-aging interventions PGC-1α regulation by exercise training and its influences on muscle function and insulin sensitivity Peroxisome proliferator-activated receptor-γ coactivator 1α (PGC-1α): transcriptional coactivator and metabolic regulator PGC-1α supports glutamine metabolism in breast cancer FGF15/19 regulates hepatic glucose metabolism by inhibiting the CREB-PGC-1α pathway Transcriptional coactivators PGC-1α and PGC-lβ control overlapping programs required for perinatal maturation of the heart Transcriptional control of mitochondrial biogenesis: the central role of PGC-1α … transcription of the peroxisome proliferator-activated receptor-γ co-activator-1α (PGC-1α) gene in skeletal muscle through the PGC-1α autoregulatory loop and … Activation of nuclear receptor coactivator PGC-1α by arginine methylation Regulation of peroxisome proliferator-activated receptor γ coactivator 1α (PGC-1α) and mitochondrial function by MEF2 and HDAC5 Nutrient control of glucose homeostasis through a complex of PGC-1α and SIRT1 PGC-1α, mitochondrial dysfunction, and Huntington's disease Metabolic adaptations through the PGC-1α and SIRT1 pathways A fundamental system of cellular energy homeostasis regulated by PGC-1α PGC-1α regulates the mitochondrial antioxidant defense system in vascular endothelial cells Sirtuin 3, a new target of PGC-1α, plays an important role in the suppression of ROS and mitochondrial biogenesis SUMOylation attenuates the function of PGC-1α A role for the transcriptional coactivator PGC-1α in muscle refueling Development of insulin resistance in mice lacking PGC-1α in adipose tissues The estrogen-related receptor α (ERRα) functions in PPARγ coactivator 1α (PGC-1α)-induced mitochondrial biogenesis Regulation of PGC-1α, a nodal regulator of mitochondrial biogenesis Insulin-regulated hepatic gluconeogenesis through FOXO1–PGC-1α interaction Regulation of PPARγ coactivator 1α (PGC-1α) signaling by an estrogen-related receptor α (ERRα) ligand PARIS (ZNF746) repression of PGC-1α contributes to neurodegeneration in Parkinson's disease Endothelial PGC-1α mediates vascular dysfunction in diabetes IRF4 is a key thermogenic transcriptional partner of PGC-1α PGC-1α regulates the neuromuscular junction program and ameliorates Duchenne muscular dystrophy Fibroblast growth factor 21 regulates energy metabolism by activating the AMPK–SIRT1–PGC-1α pathway PGC-1α expression decreases in the Alzheimer disease brain as a function of dementia The many roles of PGC-1α in muscle—recent developments The role of PGC-1α in the pathogenesis of neurodegenerative disorders The role of PGC-1α on mitochondrial function and apoptotic susceptibility in muscle Metformin induces PGC‐1α expression and selectively affects hepatic PGC‐1α functions PGC-1α is coupled to HIF-1α-dependent gene expression by increasing mitochondrial oxygen consumption in skeletal muscle cells Re-evaluating the FOXO1–PGC-1α connection PGC-1α promotes recovery after

Anti-ovarian cancer potential of phytocompound and extract from South African medicinal plants and their role in the development of chemotherapeutic agents Effect of a combination of extract from several plants on Cell‐mediated and humoral immunity of patients with advanced ovarian cancer Aqueous extract of herba Scutellaria barbatae, a Chinese herb used for ovarian cancer, induces apoptosis of ovarian cancer cell lines The inhibitory effect of ginger extract on ovarian cancer cell line; application of systems biology … , characterization, cytotoxicity, antioxidant, and anti-human ovarian cancer activities of Curcumae kwangsiensis leaf aqueous extract green-synthesized gold … Antitumor activities of Rauwolfia vomitoria extract and potentiation of carboplatin effects against ovarian cancer Effects of Agarum clathratum extract on cell death and calcium ion levels of ovarian cancer cell Huaier aqueous extract inhibits ovarian cancer cell motility via the AKT/GSK3β/β-catenin pathway Synergistic effects of green tea extract and paclitaxel in the induction of mitochondrial apoptosis in ovarian cancer cell lines Evaluation of characteristics of CD44+ CD117+ ovarian cancer stem cells in three dimensional basement membrane extract scaffold versus two dimensional … The fractionated Toona sinensis leaf extract induces apoptosis of human ovarian cancer cells and inhibits tumor growth in a murine xenograft model The induction of apoptosis in human melanoma, breast and ovarian cancer cell lines using an essential oil extract from the conifer Tetraclinis articulata. Emblica officinalis extract Induces Autophagy and Inhibits Human ovarian cancer Cell Proliferation, Angiogenesis, Growth of Mouse Xenograft Tumors The plant extract of Pao pereira potentiates carboplatin effects against ovarian cancer Anti-human ovarian cancer and cytotoxicity effects of nickel nanoparticles green-synthesized by Alhagi maurorum leaf aqueous extract Efficient biogenesis of Cu2O nanoparticles using extract of Camellia sinensis leaf: Evaluation of catalytic, cytotoxicity, antioxidant, and anti-human ovarian cancer … Characterizing the efficacy of fermented wheat germ extract against ovarian cancer and defining the genomic basis of its activity Anti-proliferative and anti-apoptotic effects of grape seed extract on chemo-resistant OVCAR-3 ovarian cancer cells Kaempferia parviflora extract inhibits TNF-α-induced release of MCP-1 in ovarian cancer cells through the suppression of NF-κB signaling Investigation of anti-human ovarian cancer effects of decorated Au nanoparticles on Thymbra spicata extract modified Fe3O4 nanoparticles Antiangiogenesis efficacy of ethanol extract from Amomum tsaoko in ovarian cancer through inducing ER stress to suppress p-STAT3/NF-kB/IL-6 and VEGF … Bitter Melon (Momordica charantia) extract Inhibits Tumorigenicity and Overcomes Cisplatin-Resistance in ovarian cancer Cells Through Targeting AMPK … … -mediated synthesis of CuO nanoparticles using aqueous leaf extract of Artemisia deserti and their anticancer effects on A2780-CP cisplatin-resistant ovarian cancer … Solanum incanum extract downregulates aldehyde dehydrogenase 1-mediated stemness and inhibits tumor formation in ovarian cancer cells … extract from Baiye No.1 Tea (Camellia sinensis) Flowers Induced S Phase Cell Cycle Arrest and Apoptosis via AKT-MDM2-p53 Signaling Pathway in ovarian cancer … Aqueous extract of Paris polyphylla (AEPP) Inhibits ovarian cancer via Suppression of Peroxisome Proliferator-Activated Receptor-Gamma Coactivator (PGC) … Overcoming cisplatin resistance by targeting the MTDH-PTEN interaction in ovarian cancer with sera derived from rats exposed to Guizhi Fuling wan extract

Anti-cancer effect of Annona Muricata Linn Leaves Crude extract (AMCE) on breast cancer cell line … ) extract Inhibits breast cancer Cell Proliferation by Modulating Cell Cycle Regulatory Genes and Promotes ApoptosisBitter Melon extract Inhibits breast cancer Cell … Anti-cancer properties of diethylether extract of wood from sukun (Artocarpus altilis) in human breast cancer (T47D) cells Effects of salvia officinalis extract on the breast cancer cell line Ganoderma lucidum extract induces cell cycle arrest and apoptosis in MCF‐7 human breast cancer cell Eugenia jambolana Lam. Berry extract Inhibits Growth and Induces Apoptosis of Human breast cancer but Not Non-Tumorigenic breast Cells Huaier aqueous extract inhibits proliferation of breast cancer cells by inducing apoptosis A phase I/II trial of a polysaccharide extract from Grifola frondosa (Maitake mushroom) in breast cancer patients: immunological effects Cytotoxic activity of Piper cubeba extract in breast cancer cell lines Anticancer activities of an anthocyanin-rich extract from black rice against breast cancer cells in vitro and in vivo Apoptosis and necrosis of human breast cancer cells by an aqueous extract of garden cress (Lepidium sativum) seeds Chemical composition of Solanum nigrum linn extract and induction of autophagy by leaf water extract and its major flavonoids in AU565 breast cancer cells Anticancer activity of litchi fruit pericarp extract against human breast cancer in vitro and in vivo Hydroxytyrosol rich extract from olive leaves modulates cell cycle progression in MCF-7 human breast cancer cells Isopropanolic black cohosh extract and recurrence-free survival after breast cancer The Anti-cancer Activities of Vernonia amygdalina extract in Human breast cancer Cell Lines Are Mediated through Caspase-Dependent and p53 … Fucoidan extract enhances the anti-cancer activity of chemotherapeutic agents in MDA-MB-231 and MCF-7 breast cancer cells Cytotoxic activity of physodic acid and acetone extract from Hypogymnia physodes against breast cancer cell lines Selective growth inhibition of human breast cancer cells by graviola fruit extract in vitro and in vivo involving downregulation of EGFR expression Antioxidant and apoptotic effects of an aqueous extract of Urtica dioica on the MCF-7 human breast cancer cell line Pomegranate fruit extract impairs invasion and motility in human breast cancer extract from Astragalus membranaceus inhibit breast cancer cells proliferation via PI3K/AKT/mTOR signaling pathway Bitter melon extract inhibits breast cancer growth in preclinical model by inducing autophagic cell death Benefit–risk profile of black cohosh (isopropanolic Cimicifuga racemosa extract) with and without St John's wort in breast cancer patients Antiproliferatory effects of crab shell extract on breast cancer cell line (MCF7) Anti-tumor potential of ethanol extract of Curcuma phaeocaulis Valeton against breast cancer cells Curcumin- and natural extract-loaded nanofibres for potential treatment of lung and breast cancer: in vitro efficacy evaluation … effects of Mangifera indica L. kernel extract on human breast cancer (MCF-7 and MDA-MB-231 cell lines) and bioactive constituents in the crude extract Cytotoxic activity of biosynthesized gold nanoparticles with an extract of the red seaweed Corallina officinalis on the MCF-7 human breast cancer cell line Anticancer and Anti-Inflammatory Properties of Ganoderma lucidum extract Effects on Melanoma and Triple-Negative breast cancer

Anti-inflammatory effects of the Nigella sativa seed extract, thymoquinone, in pancreatic cancer cells Viscum album [L.] extract therapy in patients with locally advanced or metastatic pancreatic cancer: a randomised clinical trial on overall survival Moringa Oleifera aqueous leaf extract down-regulates nuclear factor-kappaB and increases cytotoxic effect of chemotherapy in pancreatic cancer cells Anticancer effect of ginger extract against pancreatic cancer cells mainly through reactive oxygen species-mediated autotic cell death Ginkgo biloba extract kaempferol inhibits cell proliferation and induces apoptosis in pancreatic cancer cells The effect of asparagus extract on pancreatic cancer: an intriguing surprise Holy Basil leaf extract decreases tumorigenicity and metastasis of aggressive human pancreatic cancer cells in vitro and in vivo: potential role in therapy … and chemical characterization of a novel anti-human pancreatic cancer supplement by silver nanoparticles containing Zingiber officinale leaf aqueous extract PBI-05204, a supercritical CO2 extract of Nerium oleander, inhibits growth of human pancreatic cancer via targeting the PI3K/mTOR pathway Selective induction of apoptosis and autophagy through treatment with dandelion root extract in human pancreatic cancer cells Treatment of pancreatic insufficiency using pancreatic extract in patients with advanced pancreatic cancer: a pilot study (PICNIC) Impact of curcumin, raspberry extract, and neem leaf extract on rel protein-regulated cell death/radiosensitization in pancreatic cancer cells Inhibition of pancreatic cancer and potentiation of gemcitabine effects by the extract of Pao Pereira Pomegranate extract induces cell cycle arrest and alters cellular phenotype of human pancreatic cancer cells Antitumor Activities of Rauwolfia vomitoria extract and Potentiation of Gemcitabine Effects Against pancreatic cancer pancreatic enzyme extract improves survival in murine pancreatic cancer Hot water extract of Agaricus blazei Murrill specifically inhibits growth and induces apoptosis in human pancreatic cancer cells Yarrow supercritical extract exerts antitumoral properties by targeting lipid metabolism in pancreatic cancer Inhibition of pancreatic cancer stem cells by Rauwolfia vomitoria extract Anticancer activity of a lectin-rich mistletoe extract injected intratumorally into human pancreatic cancer xenografts Autophagy is involved in Ficus carica fruit extract-induced anti-tumor effects on pancreatic cancer Huaier extract restrains pancreatic cancer by suppressing Wnt/β-catenin pathway Feasibility evaluation of emodin (rhubarb extract) as an inhibitor of pancreatic cancer cell proliferation in vitro Molecular mechanisms by which a Fucus vesiculosus extract mediates cell cycle inhibition and cell death in pancreatic cancer cells extract of the medicinal plant Pao Pereira inhibits pancreatic cancer stem-like cell in vitro and in vivo Anti-pancreatic cancer effects of a polar extract from the edible sea cucumber, Cucumaria frondosa Green synthesis of reduced graphene oxide (RGO) using the plant extract of Salvia spinosa and evaluation of photothermal effect on pancreatic cancer cells Total flavonoid aglycones extract in Radix Scutellariae induces cross-regulation between autophagy and apoptosis in pancreatic cancer cells Anti-tumor effect of the extract from qingyihuaji formula on pancreatic cancer by down-regulating Notch-4 and Jagged-1 Effect of Angelica gigas Nakai Ethanol extract and Decursin on Human pancreatic cancer Cells Sedum sarmentosum Bunge extract induces apoptosis and inhibits proliferation in pancreatic cancer cells via the hedgehog signaling pathway Cyathus striatus extract Induces Apoptosis in Human pancreatic

Phase I study of green tea extract in patients with advanced lung cancer Anticancer activity and mechanism of Scutellaria barbata extract on human lung cancer cell line A549 Identification of anti-lung cancer extract from Chlorella vulgaris CC by antioxidant property using supercritical carbon dioxide extraction Cytotoxicity of Nigella sativa seed oil and extract against human lung cancer cell line MediMLP: using Grad-CAM to extract crucial variables for lung cancer postoperative complication prediction Impact of complementary mistletoe extract treatment on quality of life in breast, ovarian and non-small cell lung cancer patients a prospective randomized controlled … Antitumor effects of Laminaria extract fucoxanthin on lung cancer Effects of allyl sulfur compounds and garlic extract on the expression of Bcl-2, Bax, and p53 in non small cell lung cancer cell lines Apoptotic effect of citrus fruit extract nobiletin on lung cancer cell line A549 in vitro and in vivo extract from the Leaves of Toona sinensis Roemor Exerts Potent Antiproliferative Effect on Human lung cancer Cells Erianin, a novel dibenzyl compound in Dendrobium extract, inhibits lung cancer cell growth and migration via calcium/calmodulin-dependent ferroptosis Evaluations of thyme extract effects in human normal bronchial and tracheal epithelial cell lines and in human lung cancer cell line … extract of Scutellaria baicalensis and the active compounds induce cell cycle arrest and apoptosis including upregulation of p53 and Bax in human lung cancer cells Marsdenia tenacissima extract restored gefitinib sensitivity in resistant non-small cell lung cancer cells Biogenic synthesis of AgNPs using Artemisia oliveriana extract and their biological activities for an effective treatment of lung cancer Willow bark extract (BNO1455) and its fractions suppress growth and induce apoptosis in human colon and lung cancer cells Rosemary extract reduces Akt/mTOR/p70S6K activation and inhibits proliferation and survival of A549 human lung cancer cells The inhibitory effect of Curcuma longa extract on telomerase activity in A549 lung cancer cell line Foeniculum vulgare seed extract induces apoptosis in lung cancer cells partly through the down-regulation of Bcl-2 Anticancer effect of the water extract of a commercial Spirulina (Arthrospira platensis) product on the human lung cancer A549 cell line Supercritical carbon dioxide extract of Physalis peruviana induced cell cycle arrest and apoptosis in human lung cancer H661 cells Mountain ginseng extract exhibits anti-lung cancer activity by inhibiting the nuclear translocation of NF-κB Biomimetic synthesis of silver nanoparticles using Matricaria chamomilla extract and their potential anticancer activity against human lung cancer cells Crocus sativus L.(saffron) stigma aqueous extract induces apoptosis in alveolar human lung cancer cells through caspase-dependent pathways activation A Pilot Study of a Grape Seed Procyanidin extract for lung cancer ChemopreventionGrape Seed extract for lung cancer Chemoprevention Green-synthesis-derived CdS quantum dots using tea leaf extract: antimicrobial, bioimaging, and therapeutic applications in lung cancer cells Regulatory roles of OASL in lung cancer cell sensitivity to Actinidia chinensis Planch root extract (acRoots) Evaluation of Anti-cancer Activity of Saraca asoca Flower extract against lung cancer Cell Line White tea extract induces apoptosis in non–small cell lung cancer cells: the role of peroxisome