… . Initial studies were promising (Miserendino et al 1990). Infusion of APV prior to learning blocked fear conditioning, but infusion proior to testing had no […]

insulin & aging Reduced Circulating Insulin Enhances Insulin Sensitivity and Extends Lifespan The causal relationships between insulin levels, insulin resistance, and longevity are not fully elucidated. […]

mTor‐dependent stimulation of the association of eIF4G and eIF3 by insulin insulin signalling to mTor mediated by the Akt/PKB substrate PRAS40 The role of mammalian target […]

Monocyte chemoattractant protein-1 and macrophage inflammatory protein-2 are involved in both excitotoxin-induced neurodegeneration and regeneration excitotoxin-induced neuronal degeneration and seizure are mediated by tissue plasminogen activator […]

brain polyamine levels are altered in Alzheimer’s disease polyamine transport, accumulation, and release in brain The polyamine transporter Slc18b1(VPAT) is important for both short and long […]

skin aging skin aging skin aging Fifty years of skin aging Molecular mechanisms of skin aging: state of the art Retinoids in the treatment of skin […]

Evaluation of Anti-wrinkle effects of a novel cosmetic containing niacinamide Anti-wrinkle and anti-Inflammatory effects of active garlic components and the inhibition of MMPs via NF-κB signaling […]

anti-aging effect of astragalosides and its mechanism of action. aging: The Reality: “anti-aging” Is an Oxymoron The war on “anti-aging medicine” Role of antioxidants in the […]

The biology of Mitochondrial Uncoupling proteins The Mitochondrial Uncoupling-protein homologues Mitochondrial Uncoupling proteins—what is their physiological role? Superoxide activates Mitochondrial Uncoupling proteins The Mitochondrial Uncoupling proteins […]