The Warburg effect: 80 years on The Warburg effect: how does it benefit cancer cells? The Warburg effect in 2012 We need to talk about the […]

Reversal of obesity by targeted ablation of adipose tissue Reversal of Obesity- and Diet-Induced Insulin Resistance with Salicylates or Targeted Disruption of Ikkβ Reversal of obesity-related […]

Immunoregulatory functions of mTOR inhibition Dissecting the role of mTOR: lessons from mTOR inhibitors Updates of mTOR inhibitors mTOR inhibitors: an overview The pharmacology of mTOR […]

Molecular mechanism of nrf2 activation by oxidative stress The pathways and molecular mechanisms regulating Nrf2 activation in response to chemical stress Natural Nrf2 activators in diabetes […]

AMPK activation: a therapeutic target for type 2 diabetes? AMPK activators–potential therapeutics for metabolic and other diseases AMPK activation, a preventive therapeutic target in the transition […]

SIRT1 suppresses activator protein-1 transcriptional activity and cyclooxygenase-2 expression in macrophages Sirt 1 activator inhibits the AGE-induced apoptosis and p53 acetylation in human vascular endothelial cells […]

GSK3 inhibitors: development and therapeutic potential The conundrum of GSK3 inhibitors: is it the dawn of a new beginning? Discovery and development of GSK3 inhibitors for […]

Possible anti-obesity therapeutics from nature–A review Anti-obesity drugs: past, present and future Anti-obesity drugs: a review about their effects and safety Anti-obesity action of oolong tea […]

The lipase inhibitor tetrahydrolipstatin binds covalently to the putative active site serine of pancreatic lipase A new pancreatic lipase inhibitor isolated from the roots of Actinidia […]